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Nathan P. Staff, M.D., Ph.D.

  1. Neurologist
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Publications

  1. Wannarong T, Skolka MP, Rattanathamsakul N, Swart G, Dyck JB, Berini SE, Dubey D, Shouman K, Pinto MV, Mauermann ML, Windebank AJ, Staff NP, Klein CJ. CIDP Treatment Outcomes Correlation With First Nerve Conduction Changes: Ascertainment of Initial and Long-Term Responders. J Peripher Nerv Syst. 2025 Jun; 30 (2):e70017
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  2. Wilbanks B, Rolli J, Pearson K, Hrstka SCL, Hrstka RF, Warrington AE, Staff NP, Maher LJ 3rd. Selection of DNA Aptamers That Promote Neurite Outgrowth in Human iPSC-Derived Sensory Neuron Organoid Cultures. ACS Chem Neurosci. 2025 Apr 2; 16 (7):1258-1263 Epub 2025 Mar 17
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  3. Andrews J, Paganoni S, Macklin EA, Chibnik LB, Quintana M, Saville BR, Detry MA, Vestrucci M, Marion J, McGlothlin A, Young E, Chase M, Pothier L, Harkey B, Yu H, Sherman A, Shefner J, Hall M, Kittle G, Connolly MR, Berry JD, D'Agostino D, Tustison E, Giacomelli E, Scirocco E, Alameda G, Locatelli E, Ho D, Quick A, Heitzman D, Ajroud-Driss S, Appel SH, Shroff S, Katz J, Felice K, Maragakis NJ, Simmons Z, Goutman SA, Olney N, Miller T, Fernandes JA, Ilieva H, Jawdat O, Weiss MD, Foster L, Vu T, Ladha S, Owegi MA, Newman DS, Arcila-Londono X, Jackson CE, Swenson A, Heiman-Patterson T, Caress J, Fee D, Peltier A, Lewis R, Rosenfeld J, Walk D, Johnson K, Elliott M, Kasarskis EJ, Rutkove S, McIlduff CE, Bedlack R, Elman L, Goyal NA, Rezania K, Twydell P, Benatar M, Glass J, Cohen JA, Jones V, Zilliox L, Wymer JP, Beydoun SR, Shah J, Pattee GL, Martinez-Thompson J, Nayar S, Granit V, Donohue M, Grossman K, Campbell DJ, Qureshi IA, Cudkowicz ME, Babu S, Writing Committee for the HEALEY ALS Platform Trial. Verdiperstat in Amyotrophic Lateral Sclerosis: Results From the Randomized HEALEY ALS Platform Trial. JAMA Neurol. 2025 Apr; 82 (4):333-343 Epub 2025 Feb 17
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  4. Paramasivan NK, Sarker P, Zekeridou A, Staff NP, Klein CJ, McKeon A, Pittock SJ, Dubey D. Upper motor neuron-predominant motor neuron disease: a novel immunotherapy-responsive association of GAD65 autoimmunity. J Neurol. 2025 Feb 25; 272 (3):230
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  5. Berry JD, Maragakis NJ, Macklin EA, Chibnik LB, Quintana M, Saville BR, Detry MA, Vestrucci M, Marion J, McGlothlin A, Stommel EW, Chase M, Pothier L, Harkey BA, Yu H, Sherman A, Shefner J, Hall M, Kittle G, Babu S, Andrews J, D'Agostino D, Tustison E, Scirocco E, Giacomelli E, Alameda G, Locatelli E, Ho D, Quick A, Ajroud-Driss S, Katz J, Heitzman D, Appel SH, Shroff S, Felice KJ, Simmons Z, Miller T, Olney N, Weiss MD, Goutman SA, Fernandes JA Jr, Jawdat O, Owegi MA, Foster L, Vu T, Ilieva H, Newman DS, Arcila-Londono X, Jackson C, Ladha S, Heiman-Patterson T, Caress J, Swenson A, Peltier A, Lewis R, Fee D, Elliott M, Bedlack R, Kasarskis EJ, Elman L, Rosenfeld J, Walk D, McIlduff CE, Twydell P, Young E, Johnson K, Rezania K, Goyal NA, Cohen JA, Benatar M, Jones V, Glass J, Shah J, Beydoun SR, Wymer JP, Zilliox L, Nayar S, Pattee GL, Martinez-Thompson J, Rynders A, Evan J, Evan J, Hartford A, Sepassi M, Ho KS, Glanzman R, Greenberg B, Hotchkin MT, Paganoni S, Cudkowicz ME, Writing Committee for the HEALEY ALS Platform Trial//HEALEY ALS Platform Trial Study Group. CNM-Au8 in Amyotrophic Lateral Sclerosis: The HEALEY ALS Platform Trial. JAMA 2025 Feb 17; 333 (13):1138-49 [Epub ahead of print]
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  6. Shefner JM, Oskarsson B, Macklin EA, Chibnik LB, Quintana M, Saville BR, Detry MA, Vestrucci M, Marion J, McGlothlin A, Heiman-Patterson T, Chase M, Pothier L, Harkey BA, Yu H, Sherman AV, Hall M, Kittle G, Berry JD, Babu S, Andrews J, D'Agostino D, Tustison E, Scirocco E, Giacomelli E, Alameda G, Locatelli E, Ho D, Quick A, Ajroud-Driss S, Katz J, Heitzman D, Appel SH, Shroff S, Felice K, Maragakis NJ, Simmons Z, Miller TM, Olney N, Weiss MD, Goutman SA, Fernandes JA, Jawdat O, Owegi MA, Foster LA, Vu T, Ilieva H, Newman DS, Arcila-Londono X, Jackson CE, Ladha S, Caress JB, Swenson A, Peltier A, Lewis RA, Fee D, Elliott M, Bedlack R, Kasarskis EJ, Elman L, Rosenfeld J, Walk D, McIlduff C, Twydell P, Young E, Johnson K, Rezania K, Goyal NA, Cohen JA, Benatar M, Jones V, Shah J, Beydoun SR, Wymer JP, Zilliox L, Nayar S, Pattee GL, Martinez-Thompson J, Leitner ML, Chen K, Goldberg YP, Cohen Y, Geva M, Hayden MR, Paganoni S, Cudkowicz ME, Writing Committee for the HEALEY ALS Platform Trial//HEALEY ALS Platform Trial Study Group. Pridopidine in Amyotrophic Lateral Sclerosis: The HEALEY ALS Platform Trial. JAMA 2025 Feb 17; 333 (13):1128-37 [Epub ahead of print]
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  7. Paganoni S, Fournier CN, Macklin EA, Chibnik LB, Quintana M, Saville BR, Detry MA, Vestrucci M, Marion J, McGlothlin A, Ajroud-Driss S, Chase M, Pothier L, Harkey BA, Yu H, Sherman AV, Shefner JM, Hall M, Kittle G, Berry JD, Babu S, Andrews J, Dagostino D, Tustison E, Giacomelli E, Scirocco E, Alameda G, Locatelli E, Ho D, Quick A, Katz J, Heitzman D, Appel SH, Shroff S, Felice K, Maragakis NJ, Simmons Z, Miller TM, Olney N, Weiss MD, Goutman SA, Fernandes JA, Jawdat O, Owegi MA, Foster LA, Vu T, Ilieva H, Newman DS, Arcila-Londono X, Jackson CE, Ladha S, Heiman-Patterson T, Caress JB, Swenson A, Peltier A, Lewis R, Fee D, Elliott M, Bedlack R, Kasarskis EJ, Elman L, Rosenfeld J, Walk D, McIlduff C, Twydell P, Young E, Johnson K, Rezania K, Goyal NA, Cohen JA, Benatar M, Jones V, Glass J, Shah J, Beydoun SR, Wymer JP, Zilliox L, Nayar S, Pattee GL, Martinez-Thompson J, Harvey B, Patel S, Mahoney P, Duda PW, Cudkowicz ME, HEALEY ALS Platform Trial Study Group. Efficacy and Safety of Zilucoplan in Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial. JAMA Netw Open. 2025 Feb 3; 8 (2):e2459058 Epub 2025 Feb 03
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  8. Martinez-Thompson JM, Mazurek KA, Parra Cantu C, Naddaf E, Gogineni V, Botha H, Jones DT, Laughlin RS, Barnard L, Staff NP. Artificial intelligence models using F-wave responses predict amyotrophic lateral sclerosis. Brain. 2025 Jan 16 [Epub ahead of print]
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  9. Li Z, Weller CA, Shah S, Johnson NL, Hao Y, Jarreau PB, Roberts J, Guha D, Bereda C, Klaisner S, Machado P, Zanovello M, Prudencio M, Oskarsson B, Staff NP, Dickson DW, Fratta P, Petrucelli L, Narayan P, Cookson MR, Ward ME, Singleton AB, Nalls MA, Qi YA. ProtPipe: A Multifunctional Data Analysis Pipeline for Proteomics and Peptidomics. Genomics Proteomics Bioinformatics. 2025 Jan 15; 22 (6)
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  10. Rolli J, Pearson K, Wilbanks B, Hrstka SCL, Minotti AP, Studer L, Warrington AE, Staff NP, Maher LJ 3rd. DNA aptamers that modulate biological activity of model neurons. Mol Ther Nucleic Acids. 2024 Dec 10; 35 (4):102392 Epub 2024 Nov 16
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  11. Paganoni S, Harkey B, Giacomelli E, Cudkowicz M, HEALEY ALS Platform Trial Study Group. Lessons from the HEALEY adaptive platform trial in amyotrophic lateral sclerosis. Nat Aging. 2024 Nov; 4 (11):1512-1515
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  12. Rashed HR, Staff NP, Milone M, Mauermann ML, Berini S, Cheshire WP, Coon EA, Fealey RD, Sorenson E, Cutsforth-Gregory J, Benarroch EE, Sandroni P, Low PA, Singer W, Shouman K. Autonomic impairment in primary lateral sclerosis. Clin Auton Res. 2024 Aug; 34 (4):421-425 Epub 2024 June 12
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  13. Kherbek H, Itoh CY, Daley C, Eggers SD, Hinson S, Sarker P, Staff NP, Pittock SJ, Dubey D. Clinical and serological insights into paraneoplastic brachial amyotrophic diplegia. J Neurol. 2024 Jul; 271 (7):4620-4627 Epub 2024 May 22
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  14. Lindborg SR, Goyal NA, Katz J, Burford M, Li J, Kaspi H, Abramov N, Boulanger B, Berry JD, Nicholson K, Mozaffar T, Miller R, Jenkins L, Baloh RH, Lewis R, Staff NP, Owegi MA, Dagher B, Blondheim-Shraga NR, Gothelf Y, Levy YS, Kern R, Aricha R, Windebank AJ, Bowser R, Brown RH Jr, Cudkowicz ME. Debamestrocel multimodal effects on biomarker pathways in amyotrophic lateral sclerosis are linked to clinical outcomes. Muscle Nerve. 2024 Jun; 69 (6):719-729 Epub 2024 Apr 09
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  15. Parra-Cantu C, Martinez-Thompson JM, Linch FB, Welch TL, Chou CZ, Pattinson AK, Staff NP, Neisen M. Radiologically Inserted Gastrostomy Tube Placement Guided by the Assessment and Primary Palliative Care Provided by an Amyotrophic Lateral Sclerosis Multidisciplinary Clinic: A Single-Arm Retrospective Clinical Study. Am J Hosp Palliat Care. 2024 May; 41 (5):516-526 Epub 2023 June 02
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  16. Alberti P, Argyriou AA, Bruna J, Damaj MI, Faithfull S, Harding A, Hoke A, Knoerl R, Kolb N, Li T, Park SB, Staff NP, Tamburin S, Thomas S, Smith EL. Correction to: Considerations for establishing and maintaining international research collaboration: the example of chemotherapy‑induced peripheral neurotoxicity (CIPN)-a white paper. Support Care Cancer. 2024 Feb 21; 32 (3):175
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  17. Seddighi S, Qi YA, Brown AL, Wilkins OG, Bereda C, Belair C, Zhang YJ, Prudencio M, Keuss MJ, Khandeshi A, Pickles S, Kargbo-Hill SE, Hawrot J, Ramos DM, Yuan H, Roberts J, Sacramento EK, Shah SI, Nalls MA, Colon-Mercado JM, Reyes JF, Ryan VH, Nelson MP, Cook CN, Li Z, Screven L, Kwan JY, Mehta PR, Zanovello M, Hallegger M, Shantaraman A, Ping L, Koike Y, Oskarsson B, Staff NP, Duong DM, Ahmed A, Secrier M, Ule J, Jacobson S, Reich DS, Rohrer JD, Malaspina A, Dickson DW, Glass JD, Ori A, Seyfried NT, Maragkakis M, Petrucelli L, Fratta P, Ward ME. Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD. Sci Transl Med. 2024 Feb 14; 16 (734):eadg7162
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  18. Alberti P, Argyriou AA, Bruna J, Damaj MI, Faithfull S, Harding A, Hoke A, Knoerl R, Kolb N, Li T, Park SB, Staff NP, Tamburin S, Thomas S, Smith EL. Considerations for establishing and maintaining international research collaboration: the example of chemotherapy-induced peripheral neurotoxicity (CIPN)-a white paper. Support Care Cancer. 2024 Jan 20; 32 (2):117
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  19. Santilli AR, Martinez-Thompson JM, Speelziek SJA, Staff NP, Laughlin RS. Femoral neuropathy: A clinical and electrodiagnostic review. Muscle Nerve. 2024 Jan; 69 (1):64-71 Epub 2023 Nov 08
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  20. Cook SL, Stout C, Kirkeby L, Vidal-Folch N, Oglesbee D, Hasadsri L, Selcen D, Milone M, Anderson D, Staff NP. SMN1 c.5C>G (p.Ala2Gly) missense variant, a challenging molecular SMA diagnosis associated with mild disease, preserves SMN nuclear gems in patient-specific fibroblasts. Front Genet. 2024; 15:1406819. Epub 2024 Jul 30.
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  21. Rashed HR, Niu Z, Dyck PJ, Dyck PJB, Mauermann ML, Berini SE, Dubey D, Mills JR, Staff NP, Wu Y, Spinner RJ, Dasari S, Klein CJ. Nerve transcriptomes in autoimmune and genetic demyelinating neuropathies: Pathogenic pathway assessment of nerve demyelination. J Neuroimmunol. 2023 Nov 15; 384:578220 Epub 2023 Oct 13
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  22. Skolka M, Shelly S, Pinto MV, Dubey D, Oishi T, Uhm JH, Santilli A, Staff NP, Spinner RJ, Dyck PJB, Robertson CE, Klein CJ. Clinical, Neurophysiologic, and Pathologic Features in Patients With Early-Onset Postradiation Neuropathy. Neurology. 2023 Oct 3; 101 (14):e1455-e1460 Epub 2023 July 03
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  23. Staff NP, Hrstka SC, Dasari S, Capobianco E, Rieger S. Skin Extracellular Matrix Breakdown Following Paclitaxel Therapy in Patients with Chemotherapy-Induced Peripheral Neuropathy. Cancers (Basel). 2023 Aug 21; 15 (16)
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  24. Huber RG, Pandey S, Chhangani D, Rincon-Limas DE, Staff NP, Yeo CJJ. Identification of potential pathways and biomarkers linked to progression in ALS. Ann Clin Transl Neurol. 2023 Feb; 10 (2):150-165 Epub 2022 Dec 19
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  25. Wilkins JM, Gakh O, Guo Y, Popescu B, Staff NP, Lucchinetti CF. Biomolecular alterations detected in multiple sclerosis skin fibroblasts using Fourier transform infrared spectroscopy. Front Cell Neurosci. 2023; 17:1223912 Epub 2023 Sept 04
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  26. Nair MA, Niu Z, Madigan NN, Shin AY, Brault JS, Staff NP, Klein CJ. Clinical trials in Charcot-Marie-Tooth disorders: a retrospective and preclinical assessment. Front Neurol. 2023; 14:1251885 Epub 2023 Sept 22
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  27. Beecher G, Howe BM, Shelly S, Staff NP, Mauermann ML, Taylor BV, Spinner RJ, Tracy JA, Dyck PJB, Klein CJ. Plexus MRI helps distinguish the immune-mediated neuropathies MADSAM and MMN. J Neuroimmunol. 2022 Oct 15; 371:577953 Epub 2022 Aug 18
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  28. Miller TM, Cudkowicz ME, Genge A, Shaw PJ, Sobue G, Bucelli RC, Chiò A, Van Damme P, Ludolph AC, Glass JD, Andrews JA, Babu S, Benatar M, McDermott CJ, Cochrane T, Chary S, Chew S, Zhu H, Wu F, Nestorov I, Graham D, Sun P, McNeill M, Fanning L, Ferguson TA, Fradette S, VALOR and OLE Working Group. Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS. N Engl J Med. 2022 Sep 22; 387(12):1099-1110.
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  29. Sista SRS, Shelly S, Oskarsson B, Rubin DI, Martinez-Thompson JM, Parra-Cantu C, Staff NP, Laughlin RS. Clinical and electrophysiological findings in C9ORF72 ALS. Muscle Nerve. 2022 Sep; 66(3):270-275. Epub 2022 Jul 11.
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  30. Kelly CR, Parra-Cantu C, Thapa P, Boynton B, Selim BJ, Sorenson EJ, Martinez-Thompson JM, Mandrekar J, Staff NP. Comparative Performance of Different Respiratory Test Parameters for Detection of Early Respiratory Insufficiency in Patients With ALS. Neurology. 2022 Aug 16; 99 (7):e743-e750 Epub 2022 May 18
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  31. Peters J, Staff NP. Update on Toxic Neuropathies. Curr Treat Options Neurol. 2022 May; 24 (5):203-216 Epub 2022 Apr 06
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  32. Cudkowicz ME, Lindborg SR, Goyal NA, Miller RG, Burford MJ, Berry JD, Nicholson KA, Mozaffar T, Katz JS, Jenkins LJ, Baloh RH, Lewis RA, Staff NP, Owegi MA, Berry DA, Gothelf Y, Levy YS, Aricha R, Kern RZ, Windebank AJ, Brown RH Jr. A randomized placebo-controlled phase 3 study of mesenchymal stem cells induced to secrete high levels of neurotrophic factors in amyotrophic lateral sclerosis. Muscle Nerve. 2022 Mar; 65 (3):291-302 Epub 2022 Jan 05
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  33. Groen CM, Podratz JL, Pathoulas J, Staff N, Windebank AJ. Genetic Reduction of Mitochondria Complex I Subunits is Protective against Cisplatin-Induced Neurotoxicity in Drosophila. J Neurosci. 2022 Feb 02; 42(5):922-937. Epub 2021 Dec 10.
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  34. Forkner KA, Wissman AW, Jimison RC, Nelson KB, Wuertz RE, Silvano CJ, Barreto EF, Eckel Passow JE, Enders FT, Staff NP. Lessons Learned from Clinical and Translational Science Faculty and Student Survey as COVID-19 Pandemic Continues to Shift Education Online. J Med Educ Curric Dev. 2022 Jan-Dec; 9:23821205211073253 Epub 2022 Jan 11
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  35. Schalk G, Worrell S, Mivalt F, Belsten A, Kim I, Morris JM, Hermes D, Klassen BT, Staff NP, Messina S, Kaufmann T, Rickert J, Brunner P, Worrell GA, Miller KJ. Toward a fully implantable ecosystem for adaptive neuromodulation in humans: Preliminary experience with the CorTec BrainInterchange device in a canine model. Front Neurosci. 2022; 16:932782 Epub 2022 Dec 19
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  36. Oskarsson B, Maragakis N, Bedlack RS, Goyal N, Meyer JA, Genge A, Bodkin C, Maiser S, Staff N, Zinman L, Olney N, Turnbull J, Brooks BR, Klonowski E, Makhay M, Yasui S, Matsuda K. MN-166 (ibudilast) in amyotrophic lateral sclerosis in a Phase IIb/III study: COMBAT-ALS study design. Neurodegener Dis Manag. 2021 Dec; 11 (6):431-443 Epub 2021 Nov 24
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  37. Smith C, Crowley A, Munsie M, Behfar A, DeMartino ES, Staff NP, Shapiro SA, Master Z. Academic Physician Specialists' Approaches to Counseling Patients Interested in Unproven Stem Cell and Regenerative Therapies-A Qualitative Analysis. Mayo Clin Proc. 2021 Dec; 96 (12):3086-3096 Epub 2021 Aug 26
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  38. Johnson SA, Shouman K, Shelly S, Sandroni P, Berini SE, Dyck PJB, Hoffman EM, Mandrekar J, Niu Z, Lamb CJ, Low PA, Singer W, Mauermann ML, Mills J, Dubey D, Staff NP, Klein CJ. Small Fiber Neuropathy Incidence, Prevalence, Longitudinal Impairments, and Disability. Neurology. 2021 Nov 30; 97 (22):e2236-e2247 Epub 2021 Oct 27
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  39. Albany C, Dockter T, Wolfe E, Le-Rademacher J, Wagner-Johnston N, Einhorn L, Lafky JM, Smith E, Pachman D, Staff N, Ma C, Loprinzi CL, Costello BA. Correction to: Cisplatin-associated neuropathy characteristics compared with those associated with other neurotoxic chemotherapy agents (Alliance A151724). Support Care Cancer. 2021 Nov; 29 (11):7129-7130
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  40. Cudkowicz M, Genge A, Maragakis N, Petri S, van den Berg L, Aho VV, Sarapohja T, Kuoppamaki M, Garratt C, Al-Chalabi A, REFALS investigators. Safety and efficacy of oral levosimendan in people with amyotrophic lateral sclerosis (the REFALS study): a randomised, double-blind, placebo-controlled phase 3 trial. Lancet Neurol 2021 Oct; 20 (10):821-831
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  41. Smith C, Crowley A, Munsie M, DeMartino ES, Staff NP, Shapiro S, Master Z. Academic physician specialists' views toward the unproven stem cell intervention industry: areas of common ground and divergence. Cytotherapy. 2021 Apr; 23 (4):348-356 Epub 2021 Feb 06
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  42. Krull AA, Setter DO, Gendron TF, Hrstka SCL, Polzin MJ, Hart J, Dudakovic A, Madigan NN, Dietz AB, Windebank AJ, van Wijnen AJ, Staff NP. Alterations of mesenchymal stromal cells in cerebrospinal fluid: insights from transcriptomics and an ALS clinical trial. Stem Cell Res Ther. 2021 Mar 18; 12 (1):187
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  43. Albany C, Dockter T, Wolfe E, Le-Rademacher J, Wagner-Johnston N, Einhorn L, Lafky JM, Smith E, Pachman D, Staff N, Ma C, Loprinzi CL, Costello BA. Cisplatin-associated neuropathy characteristics compared with those associated with other neurotoxic chemotherapy agents (Alliance A151724). Support Care Cancer. 2021 Feb; 29 (2):833-840 Epub 2020 June 04
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  44. Madhavan AA, Carr CM, Alkhateeb H, Staff NP, Naddaf E. Nelarabine-Induced Myelotoxicity. Neurology. 2021 Jan 26; 96 (4):175-176 Epub 2020 Dec 11
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  45. Hrstka SCL, Ankam S, Agac B, Klein JP, Moore RA, Narapureddy B, Schneider I, Hrstka RF, Dasari S, Staff NP. Proteomic analysis of human iPSC-derived sensory neurons implicates cell stress and microtubule dynamics dysfunction in bortezomib-induced peripheral neurotoxicity. Exp Neurol. 2021 Jan; 335:113520 Epub 2020 Oct 29
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  46. Paganoni S, De Marchi F, Chan J, Thrower SK, Staff NP, Datta N, Kisanuki YY, Drory V, Fournier C, Pioro EP, Goutman SA, Atassi N, Jeon M, Caldwell S, Mcdonough T, Gentile C, Liu J, Turner M, Denny C, Felice K, Green M, Scarberry S, Abu-Saleh S, Nefussy B, Hastings D, Kim S, Swihart B, Arcila-Londono X, Newman DS, Silverman M, Genge A, Salmon K, Elman L, Mccluskey L, Almasy K, Gotkine M, Goslin K, Cummings A, Edwards EK, Rivner M, Bouchard K, Quarles B, Kwan J, Jaffa M, Baloh R, Allred P, Walk D, Maiser S, Manousakis G, Ferment V, Fernandes JAM Jr, Thaisetthawatkul P, Heimes D, Phillips M, Sams L, Kahler M, Corcoran A, Larriviere DG, Chotto S, Juba G, NEALS PLS Registry Study Group. The NEALS primary lateral sclerosis registry. Amyotroph Lateral Scler Frontotemporal Degener. 2020 Nov; 21 (sup1):74-81 Epub 2020 Sept 11
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  47. Prudencio M, Garcia-Moreno H, Jansen-West KR, Al-Shaikh RH, Gendron TF, Heckman MG, Spiegel MR, Carlomagno Y, Daughrity LM, Song Y, Dunmore JA, Byron N, Oskarsson B, Nicholson KA, Staff NP, Gorcenco S, Puschmann A, Lemos J, Januário C, LeDoux MS, Friedman JH, Polke J, Labrum R, Shakkottai V, McLoughlin HS, Paulson HL, Konno T, Onodera O, Ikeuchi T, Tada M, Kakita A, Fryer JD, Karremo C, Gomes I, Caviness JN, Pittelkow MR, Aasly J, Pfeiffer RF, Veerappan V, Eggenberger ER, Freeman WD, Huang JF, Uitti RJ, Wierenga KJ, Marin Collazo IV, Tipton PW, van Gerpen JA, van Blitterswijk M, Bu G, Wszolek ZK, Giunti P, Petrucelli L. Toward allele-specific targeting therapy and pharmacodynamic marker for spinocerebellar ataxia type 3. Sci Transl Med. 2020 Oct 21; 12(566).
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  48. Staff NP. Peripheral Neuropathies Due to Vitamin and Mineral Deficiencies, Toxins, and Medications. Continuum (Minneap Minn). 2020 Oct; 26 (5):1280-1298
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  49. Goyal NA, Berry JD, Windebank A, Staff NP, Maragakis NJ, van den Berg LH, Genge A, Miller R, Baloh RH, Kern R, Gothelf Y, Lebovits C, Cudkowicz M. Addressing heterogeneity in amyotrophic lateral sclerosis CLINICAL TRIALS. Muscle Nerve. 2020 Aug; 62 (2):156-166 Epub 2020 Jan 22
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  50. Wilkins JM, Gakh O, Kabiraj P, McCarthy CB, Tobin WO, Howe CL, Staff NP, Lucchinetti CF. Signatures of cell stress and altered bioenergetics in skin fibroblasts from patients with multiple sclerosis Aging (Albany NY). 2020; 12(14):15134-15156.
  51. Miller KJ, Hermes D, Staff NP. The current state of electrocorticography-based brain-computer interfaces. Neurosurg Focus. 2020 Jul; 49 (1):E2
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  52. Lehmann HC, Staff NP, Hoke A. Modeling chemotherapy induced peripheral neuropathy (CIPN) in vitro: Prospects and limitations. Exp Neurol. 2020 Apr; 326:113140 Epub 2019 Dec 05
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  53. Laughlin RS, Johnson RL, Burkle CM, Staff NP. Postsurgical Neuropathy: A Descriptive Review. Mayo Clin Proc. 2020 Feb; 95 (2):355-369
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  54. Staff NP, Fehrenbacher JC, Caillaud M, Damaj MI, Segal RA, Rieger S. Pathogenesis of paclitaxel-induced peripheral neuropathy: A current review of in vitro and in vivo findings using rodent and human model systems. Exp Neurol. 2020 Feb; 324:113121 Epub 2019 Nov 21
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  55. Oishi T, Kogelschatz CJ, Young NP, Hoffmann EM, Staff NP, Visscher SL, Borah BJ, Krauss WE, Arumaithurai K, Shelly S, Ansell SM, Klein CJ. Expanded neuromuscular morbidity in Hodgkin lymphoma after radiotherapy. Brain Commun. 2020; 2 (1):fcaa050 Epub 2020 Apr 25
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  56. Loprinzi CL, Hershman DL, Staff N. Neuronal Protection for Chemotherapy Neuropathy Prevention? J Natl Cancer Inst 2020 Jan 1; 112 (1):3-4
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  57. Klein JP, Sun Z, Staff NP. Association between ALS and retroviruses: evidence from bioinformatics analysis. BMC Bioinformatics. 2019 Dec 20; 20 (Suppl 24):680
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  58. Berry JD, Cudkowicz ME, Windebank AJ, Staff NP, Owegi M, Nicholson K, McKenna-Yasek D, Levy YS, Abramov N, Kaspi H, Mehra M, Aricha R, Gothelf Y, Brown RH. NurOwn, phase 2, randomized, clinical trial in patients with ALS: Safety, clinical, and biomarker results. Neurology. 2019 Dec 10; 93 (24):e2294-e2305 Epub 2019 Nov 18
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  59. Chan A, Hertz DL, Morales M, Adams EJ, Gordon S, Tan CJ, Staff NP, Kamath J, Oh J, Shinde S, Pon D, Dixit N, D'Olimpio J, Dumitrescu C, Gobbo M, Kober K, Mayo S, Pang L, Subbiah I, Beutler AS, Peters KB, Loprinzi C, Lustberg MB. Biological predictors of chemotherapy-induced peripheral neuropathy (CIPN): MASCC neurological complications working group overview. Support Care Cancer. 2019 Oct; 27 (10):3729-3737 Epub 2019 July 30
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  60. Mohassel P, Liewluck T, Hu Y, Ezzo D, Ogata T, Saade D, Neuhaus S, Bolduc V, Zou Y, Donkervoort S, Medne L, Sumner CJ, Dyck PJB, Wierenga KJ, Tennekoon G, Finkel RS, Chen J, Winder TL, Staff NP, Foley AR, Koch M, Bonnemann CG. Dominant collagen XII mutations cause a distal myopathy. Ann Clin Transl Neurol. 2019 Oct; 6 (10):1980-1988 Epub 2019 Sept 11
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  61. Cavaletti G, Alberti P, Argyriou AA, Lustberg M, Staff NP, Tamburin S, Toxic Neuropathy Consortium of the Peripheral Nerve Society. Chemotherapy-induced peripheral neurotoxicity: A multifaceted, still unsolved issue. J Peripher Nerv Syst. 2019 Oct; 24 Suppl 2:S6-S12
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  62. Islam B, Lustberg M, Staff NP, Kolb N, Alberti P, Argyriou AA. Vinca alkaloids, thalidomide and eribulin-induced peripheral neurotoxicity: From pathogenesis to treatment. J Peripher Nerv Syst. 2019 Oct; 24 Suppl 2:S63-S73
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  63. Staff NP, Cavaletti G, Islam B, Lustberg M, Psimaras D, Tamburin S. Platinum-induced peripheral neurotoxicity: From pathogenesis to treatment. J Peripher Nerv Syst. 2019 Oct; 24 Suppl 2:S26-S39
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  64. Ankam S, Rovini A, Baheti S, Hrstka R, Wu Y, Schmidt K, Wang H, Madigan N, Koenig LS, Stelzig K, Resch Z, Klein CJ, Sun Z, Staff NP. DNA methylation patterns in human iPSC-derived sensory neuronal differentiation. Epigenetics. 2019 Sep; 14 (9):927-937 Epub 2019 June 06
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  65. Staff NP, Dyck PJB. On the Association Between Fluoroquinolones and Neuropathy. JAMA Neurol 2019 Jul 1; 76 (7):753-754
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  66. Speelziek SJA, Staff NP, Johnson RL, Sierra RJ, Laughlin RS. Clinical spectrum of neuropathy after primary total knee arthroplasty: A series of 54 cases. Muscle Nerve. 2019 Jun; 59 (6):679-682 Epub 2019 Apr 04
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  67. Staff NP, Jones DT, Singer W. Mesenchymal Stromal Cell Therapies for Neurodegenerative Diseases. Mayo Clin Proc. 2019 May; 94 (5):892-905
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  68. van den Berg LH, Sorenson E, Gronseth G, Macklin EA, Andrews J, Baloh RH, Benatar M, Berry JD, Chio A, Corcia P, Genge A, Gubitz AK, Lomen-Hoerth C, McDermott CJ, Pioro EP, Rosenfeld J, Silani V, Turner MR, Weber M, Brooks BR, Miller RG, Mitsumoto H, Airlie House ALS Clinical Trials Guidelines Group. Revised Airlie House consensus guidelines for design and implementation of ALS clinical trials. Neurology 2019 Apr 2; 92 (14):e1610-e1623 Epub 2019 Mar 08
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  69. Pinto MV, Spinner RJ, Staff NP. A treatable hypertrophic neuropathy. Pract Neurol. 2019 Feb; 19 (1):80-82 Epub 2018 Nov 17
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  70. Greenberg-Worisek AJ, Campbell KA, Klee EW, Staff NP, Schimmenti LA, Weavers KM, Ekker SC, Windebank AJ. Case-Based Learning in Translational Biomedical Research Education: Providing Realistic and Adaptive Skills for Early-Career Scientists. Acad Med. 2019 Feb; 94 (2):213-216
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  71. Oskarsson B, Gendron TF, Staff NP. Amyotrophic Lateral Sclerosis: An Update for 2018. Mayo Clin Proc. 2018 Nov; 93 (11):1617-1628 Epub 2018 July 04
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  72. Shah A, Hoffman EM, Mauermann ML, Loprinzi CL, Windebank AJ, Klein CJ, Staff NP. Incidence and disease burden of chemotherapy-induced peripheral neuropathy in a population-based cohort. J Neurol Neurosurg Psychiatry. 2018 Jun; 89 (6):636-641 Epub 2018 Feb 08
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  73. Davies JL, Engelstad JK Sr, E Gove L, Linbo LK, Carter RE, Lynch C, Staff NP, Klein CJ, Dyck PJB, Herrmann DN, Dyck PJ. Somatotopic heat pain thresholds and intraepidermal nerve fibers in health. Muscle Nerve. 2018 Mar 15 [Epub ahead of print]
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  74. Pachman DR, Dockter T, Zekan PJ, Fruth B, Ruddy KJ, Ta LE, Lafky JM, Dentchev T, Le-Lindqwister NA, Sikov WM, Staff N, Beutler AS, Loprinzi CL. A pilot study of minocycline for the prevention of paclitaxel-associated neuropathy: ACCRU study RU221408I. Support Care Cancer. 2017 Nov; 25 (11):3407-3416 Epub 2017 May 27
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  75. Madigan NN, Staff NP, Windebank AJ, Benarroch EE. Genome editing technologies and their potential to treat neurologic disease. Neurology. 2017 Oct 17; 89 (16):1739-1748 Epub 2017 Sept 20
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  76. Kao JC, Liao B, Markovic SN, Klein CJ, Naddaf E, Staff NP, Liewluck T, Hammack JE, Sandroni P, Finnes H, Mauermann ML. Neurological Complications Associated With Anti-Programmed Death 1 (PD-1) Antibodies. JAMA Neurol. 2017 Oct 1; 74 (10):1216-1222
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  77. Alhammad RM, Dronca RS, Kottschade LA, Turner HJ, Staff NP, Mauermann ML, Tracy JA, Klein CJ. Brachial Plexus Neuritis Associated With Anti-Programmed Cell Death-1 Antibodies: Report of 2 Cases. Mayo Clin Proc Innov Qual Outcomes. 2017 Sep; 1 (2):192-197 Epub 2017 Sept 01
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  78. Hoffman EM, Watson JC, St Sauver J, Staff NP, Klein CJ. Association of Long-term Opioid Therapy With Functional Status, Adverse Outcomes, and Mortality Among Patients With Polyneuropathy. JAMA Neurol. 2017 Jul 1; 74 (7):773-779
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  79. Staff NP, Grisold A, Grisold W, Windebank AJ. Chemotherapy-induced peripheral neuropathy: A current review. Ann Neurol. 2017 Jun; 81 (6):772-781 Epub 2017 June 05
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  80. Leon-Ferre R, Ruddy KJ, Staff NP, Loprinzi CL. Fit for Chemo: Nerves May Thank You. J Natl Cancer Inst 2017 Feb; 109 (2) Epub 2016 Oct 28
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  81. Gustafson MP, Staff NP, Bornschlegl S, Butler GW, Maas ML, Kazamel M, Zubair A, Gastineau DA, Windebank AJ, Dietz AB. Comprehensive immune profiling reveals substantial immune system alterations in a subset of patients with amyotrophic lateral sclerosis. PLoS One. 2017; 12(7):e0182002. Epub 2017 Jul 25.
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  82. Pachman DR, Qin R, Seisler D, Smith EM, Kaggal S, Novotny P, Ruddy KJ, Lafky JM, Ta LE, Beutler AS, Wagner-Johnston ND, Staff NP, Grothey A, Dougherty PM, Cavaletti G, Loprinzi CL. Comparison of oxaliplatin and paclitaxel-induced neuropathy (Alliance A151505). Support Care Cancer. 2016 Dec; 24 (12):5059-5068 Epub 2016 Aug 18
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  83. Staff NP, Madigan NN, Morris J, Jentoft M, Sorenson EJ, Butler G, Gastineau D, Dietz A, Windebank AJ. Safety of intrathecal autologous adipose-derived mesenchymal stromal cells in patients with ALS. Neurology. 2016 Nov 22; 87 (21):2230-2234 Epub 2016 Oct 26
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  84. Staff NP. Variability in Amyotrophic Lateral Sclerosis. JAMA Neurol 2016 Jul 1; 73 (7):781-2
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  85. Liewluck T, Milone M, Tian X, Engel AG, Staff NP, Wong LJ. Adult-onset respiratory insufficiency, scoliosis, and distal joint hyperlaxity in patients with multiminicore disease due to novel Megf10 mutations. Muscle Nerve. 2016 Jun; 53 (6):984-8 Epub 2016 Apr 25
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  86. Staff NP, Appel SH. The immune system continues to knock at the ALS door. Neuromuscul Disord 2016 Jun; 26 (6):335-6 Epub 2016 Apr 19
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  87. Podratz JL, Kulkarni A, Pleticha J, Kanwar R, Beutler AS, Staff NP, Windebank AJ. Neurotoxicity to DRG neurons varies between rodent strains treated with cisplatin and bortezomib. J Neurol Sci. 2016 Mar 15; 362:131-5. Epub 2015 Dec 28.
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  88. Pachman DR, Qin R, Seisler DK, Smith EM, Beutler AS, Ta LE, Lafky JM, Wagner-Johnston ND, Ruddy KJ, Dakhil S, Staff NP, Grothey A, Loprinzi CL. Clinical Course of Oxaliplatin-Induced Neuropathy: Results From the Randomized Phase III Trial N08CB (Alliance). J Clin Oncol. 2015 Oct 20; 33 (30):3416-22 Epub 2015 Aug 17
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  89. Staff NP, Amrami KK, Howe BM. Magnetic resonance imaging abnormalities of peripheral nerve and muscle are common in amyotrophic lateral sclerosis and share features with multifocal motor neuropathy. Muscle Nerve. 2015 Jul; 52 (1):137-9 Epub 2015 May 28
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  90. Johnson RL, Warner ME, Staff NP, Warner MA. Neuropathies after surgery: Anatomical considerations of pathologic mechanisms. Clin Anat. 2015 Jul; 28 (5):678-82 Epub 2015 May 14
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  91. Piccione EA, Sletten DM, Staff NP, Low PA. Autonomic system and amyotrophic lateral sclerosis. Muscle Nerve. 2015 May; 51(5):676-9. Epub 2015 Mar 31.
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  92. Chen BK, Staff NP, Knight AM, Nesbitt JJ, Butler GW, Padley DJ, Parisi JE, Dietz AB, Windebank AJ. A safety study on intrathecal delivery of autologous mesenchymal stromal cells in rabbits directly supporting Phase I human trials. Transfusion. 2015 May; 55(5):1013-20. Epub 2014 Nov 21.
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  93. Hoffman EM, Staff NP, Robb JM, St Sauver JL, Dyck PJ, Klein CJ. Impairments and comorbidities of polyneuropathy revealed by population-based analyses. Neurology. 2015 Apr 21; 84 (16):1644-51 Epub 2015 Apr 01
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  94. Johnson C, Pankratz VS, Velazquez AI, Aakre JA, Loprinzi CL, Staff NP, Windebank AJ, Yang P. Candidate pathway-based genetic association study of platinum and platinum-taxane related toxicity in a cohort of primary lung cancer patients. J Neurol Sci. 2015 Feb 15; 349 (1-2):124-8 Epub 2015 Jan 05
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  95. Staff NP, Windebank AJ. Peripheral neuropathy due to vitamin deficiency, toxins, and medications. Continuum. 2014 Oct; 20(5):1293-306.
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  96. Staff NP, Runge BK, Windebank AJ. Breaking down translation barriers: investigator's perspective. Sci Transl Med. 2014 Sep 3; 6 (252):252cm7
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  97. Berini SE, Spinner RJ, Jentoft ME, Engelstad JK, Staff NP, Suanprasert N, Dyck PJ, Klein CJ. Chronic meralgia paresthetica and neurectomy: a clinical pathologic study. Neurology. 2014 Apr 29; 82 (17):1551-5 Epub 2014 Mar 28
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  98. Laughlin RS, Dyck PJ, Watson JC, Spinner RJ, Amrami KK, Sierra RJ, Trousdale RT, Staff NP. Ipsilateral inflammatory neuropathy after hip surgery. Mayo Clin Proc. 2014 Apr; 89(4):454-61. Epub 2014 Jan 04.
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  99. Staff NP, Dyck PJ, Dyck PJ, Warner MA. Postsurgical inflammatory neuropathy should be considered in the differential diagnosis of diaphragm paralysis after surgery. Anesthesiology 2014 Apr; 120 (4):1057
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  100. Staff NP, Podratz JL, Grassner L, Bader M, Paz J, Knight AM, Loprinzi CL, Trushina E, Windebank AJ. Bortezomib alters microtubule polymerization and axonal transport in rat dorsal root ganglion neurons. Neurotoxicology. 2013 Dec; 39:124-31. Epub 2013 Sep 12.
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  101. Herrmann DN, Staff NP, Dyck PJ, Dyck PJ. Assessing decreased sensation and increased sensory phenomena in diabetic polyneuropathies. Diabetes. 2013 Nov; 62 (11):3677-86
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  102. Podratz JL, Staff NP, Boesche JB, Giorno NJ, Hainy ME, Herring SA, Klennert MT, Milaster C, Nowakowski SE, Krug RG 2nd, Peng Y, Windebank AJ. An automated climbing apparatus to measure chemotherapy-induced neurotoxicity in Drosophila melanogaster. Fly (Austin). 2013 Jul-Sep; 7(3):187-92. Epub 2013 May 21.
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  103. Mauermann ML, Blumenreich MS, Dispenzieri A, Staff NP. A case of peripheral nerve microvasculitis associated with multiple myeloma and bortezomib treatment. Muscle Nerve. 2012 Dec; 46(6):970-7.
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  104. Massie R, Mauermann ML, Staff NP, Amrami KK, Mandrekar JN, Dyck PJ, Klein CJ, Dyck PJ, Dyck PJ. Diabetic cervical radiculoplexus neuropathy: a distinct syndrome expanding the spectrum of diabetic radiculoplexus neuropathies. Brain. 2012 Oct; 135 (Pt 10):3074-88
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  105. Huang JF, Aksamit AJ, Staff NP. MRI and PET imaging discordance in neurosarcoidosis. Neurology. 2012 Sep 4; 79(10):1070.
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  106. Podratz JL, Staff NP, Froemel D, Wallner A, Wabnig F, Bieber AJ, Tang A, Windebank AJ. Drosophila melanogaster: a new model to study cisplatin-induced neurotoxicity. Neurobiol Dis. 2011 Aug; 43(2):330-7. Epub 2011 Apr 15.
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  107. Staff NP, Benarroch EE, Klein CJ. Neuronal intracellular transport and neurodegenerative disease. Neurology. 2011 Mar 15; 76 (11):1015-20
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  108. Podratz JL, Knight AM, Ta LE, Staff NP, Gass JM, Genelin K, Schlattau A, Lathroum L, Windebank AJ. Cisplatin induced mitochondrial DNA damage in dorsal root ganglion neurons. Neurobiol Dis. 2011 Mar; 41(3):661-8. Epub 2010 Dec 08.
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  109. Staff NP, Engelstad J, Klein CJ, Amrami KK, Spinner RJ, Dyck PJ, Warner MA, Warner ME, Dyck PJ, Dyck PJ. Post-surgical inflammatory neuropathy. Brain. 2010 Oct; 133 (10):2866-80 Epub 2010 Sept 15
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  110. Staff NP, Figueroa JJ, Parisi JE, Klein CJ. Hypertrophic nerves producing myelopathy in fulminant CIDP. Neurology. 2010 Aug 24; 75 (8):750
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  111. Staff NP, Bosch EP, Engelstad J, Moynihan TJ, Spinner RJ, Dyck PJ, Dyck PJ. Metastatic lobular breast adenocarcinoma presenting as cauda equina syndrome. J Peripher Nerv Syst 2010 Mar; 15 (1):75-8
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  112. Staff NP, Lucchinetti CF, Keegan BM. Multiple sclerosis with predominant, severe cognitive impairment. Arch Neurol. 2009 Sep; 66 (9):1139-43
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  113. Miller RF, Staff NP, Velte TJ. Form and function of ON-OFF amacrine cells in the amphibian retina. J Neurophysiol. 2006 May; 95(5):3171-90. Epub 2006 Feb 15.
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  114. Cooper DC, Moore SJ, Staff NP, Spruston N. Psychostimulant-induced plasticity of intrinsic neuronal excitability in ventral subiculum. J Neurosci. 2003 Oct 29; 23(30):9937-46.
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  115. Staff NP, Spruston N. Intracellular correlate of EPSP-spike potentiation in CA1 pyramidal neurons is controlled by GABAergic modulation. Hippocampus. 2003; 13(7):801-5.
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  116. Golding NL, Staff NP, Spruston N. Dendritic spikes as a mechanism for cooperative long-term potentiation. Nature. 2002 Jul 18; 418(6895):326-31.
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  117. Miller RF, Fagerson MH, Staff NP, Wolfe R, Doerr T, Gottesman J, Sikora MA, Schuneman R. Structure and functional connections of presynaptic terminals in the vertebrate retina revealed by activity-dependent dyes and confocal microscopy. J Comp Neurol. 2001 Aug 20; 437(2):129-55.
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  118. Jung HY, Staff NP, Spruston N. Action potential bursting in subicular pyramidal neurons is driven by a calcium tail current. J Neurosci. 2001 May 15; 21(10):3312-21.
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  119. Staff NP, Jung HY, Thiagarajan T, Yao M, Spruston N. Resting and active properties of pyramidal neurons in subiculum and CA1 of rat hippocampus. J Neurophysiol. 2000 Nov; 84(5):2398-408.
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