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Shane A. Shapiro, M.D.

  1. Sports Medicine Specialist
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Publications

  1. Pincelli TP, Zawawi S, Shapiro SA, Heckman MG, Hochwald AP, Arthurs J, Tolaymat L, Bruce A. Evaluation of Platelet-rich Plasma and Microneedling for Facial Skin Rejuvenation. Plast Reconstr Surg Glob Open. 2024 May; 12 (5):e5829 Epub 2024 May 20
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  2. Hurley ET, Sherman SL, Stokes DJ, Rodeo SA, Shapiro SA, Mautner K, Buford DA, Dragoo JL, Mandelbaum BR, Zaslav KR, Cole BJ, Frank RM, Members of the Biologics Association. Experts Achieve Consensus on a Majority of Statements Regarding Platelet-Rich Plasma Treatments for Treatment of Musculoskeletal Pathology. Arthroscopy. 2024 Feb; 40 (2):470-477.e1 Epub 2023 Aug 23
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  3. Vomer RP 2nd, Montero DP, Shapiro S, York E, Memon S, Fungwe C, Pujalte GGA. From Dugout to the Mound: A Tale of Platelet-Rich Performance. Cureus. 2023 Dec; 15 (12):e50600 Epub 2023 Dec 15
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  4. Hassoun S, Arthurs J, Shapiro S, Heckman M. A Modified Study Design for Blinded Randomized Controlled Trial in Orthobiologic Therapy Journal of Orthopedics and Orthopedic Surgery. Nov 2023; 4(3).
  5. Pincelli T, Zawawi S, Shapiro S, Heckman MG, Hochwald AP, Desmond C, Arthurs J, Tolaymat L, Forte A, Bruce A. A Pilot, Randomized, Single-Blind, Controlled Study Evaluating the Use of Platelet Rich Plasma (PRP) for Hand Skin Rejuvenation. Plast Reconstr Surg. 2023 Oct 30 [Epub ahead of print]
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  6. Kawam O, Zhu X, Eton DT, Martin-Lillie C, Finney Rutten LJ, Shapiro S, Tilburt JC, Master Z. Designing persuasive health education for patients seeking unproven stem cell interventions. Stem Cell Reports. 2023 Aug 8; 18 (8):1549-1554
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  7. Pujalte G, Hudspeth LJ, Troyer WD, Shapiro SA. Ultrasound-guided injection of the long head of the biceps tendon sheath with concomitant subacromial bursa injection through the same needlestick. Clin Anat. 2023 Apr; 36 (3):400-405 Epub 2022 Oct 17
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  8. Arthurs JR, Nordan LM, Hultgren BH, Heckman MG, Martinez D, Master Z, Shapiro SA. Author Correction: Patients seeking stem cell therapies-a prospective qualitative analysis from a Regenerative Medicine Consult Service. NPJ Regen Med. 2023 Feb 2; 8 (1):5 Epub 2023 Feb 02
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  9. Shapiro SA, Master Z, Arthurs JR, Mautner K. Tiered approach to considering orthobiologics for patients with musculoskeletal conditions. Br J Sports Med. 2023 Feb; 57 (3):179-180 Epub 2023 Jan 17
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  10. Walker SA, Davidovich I, Yang Y, Lai A, Goncalves JP, Deliwala V, Busatto S, Shapiro S, Koifman N, Salomon C, Talmon Y, Wolfram J. Sucrose-based cryoprotective storage of extracellular vesicles. Extracell Vesicle. 2022 Dec; 1 Epub 2022 Nov 21
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  11. Schoch BS, Werner BC, Shapiro SA, Camp CL, Chalmers PN, Cancienne JM. Effect of Bone Marrow Aspirate Concentrate and Platelet-Rich Plasma Augmentation on the Rate of Revision Rotator Cuff Repair. Orthop J Sports Med. 2022 Nov; 10 (11):23259671221127004 Epub 2022 Nov 03
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  12. Murray IR, Chahla J, Wordie SJ, Shapiro SA, Piuzzi NS, Frank RM, Halbrecht J, Okada K, Nakamura N, Mandelbaum B, Dragoo JL, Borg-Stein J, Anz A, Gobbi A, Gomoll AH, Cole BJ, Lattermann C, Chu C, Grande DA, Saris DBF, Flanigan D, Kon E, Muschler GF, Malanga GA, Dummer G, Farr J, Tokish JM, Spindler KP, Horsch K, Zaslav K, McIntyre LF, Sgaglione NA, Sherman SL, Rodeo S, Awan TM, Vangsness CT, Biologics Association. Regulatory and Ethical Aspects of Orthobiologic Therapies. Orthop J Sports Med. 2022 Nov; 10 (11):23259671221101626 Epub 2022 Nov 30
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  13. Shapiro SA, Arthurs JR. Ultrasound-guided needle placement for bone marrow aspiration of the anterior iliac crest Journal of Cartilage and Joint Preservation. 2022.
  14. Arthurs JR, Nordan LM, Hultgren BH, Heckman MG, Martinez D, Master Z, Shapiro SA. Patients seeking stem cell therapies-a prospective qualitative analysis from a Regenerative Medicine Consult Service. NPJ Regen Med. 2022 Mar 25; 7 (1):20
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  15. Shapiro SA, Finnoff JT, Awan TM, Borg-Stein JP, Harmon KG, Herman DC, Malanga G, Master Z, Mautner K. Highlights from the American Medical Society for Sports Medicine position statement on responsible use of regenerative medicine and orthobiologics in sports medicine. British Journal of Sports Medicine. 2022.
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  16. Arthurs JR, Martin Lillie CM, Master Z, Shapiro SA. The Direct to Consumer Stem Cell Market and the Role of Primary Care Providers in Correcting Misinformation. J Prim Care Community Health. 2022 Jan-Dec; 13:21501319221121460
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  17. Arthurs JR, Master Z, Shapiro SA. Opinion: Patient reported motivations for seeking stem cell therapy and considerations for counseling. J Orthop Orthop Surg. 2022; 3 (3):1-3 Epub 2022 Sept 15
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  18. Wang X, Pham A, Kang L, Walker SA, Davidovich I, Iannotta D, TerKonda SP, Shapiro S, Talmon Y, Pham S, Wolfram J. Effects of Adipose-Derived Biogenic Nanoparticle-Associated microRNA-451a on Toll-like Receptor 4-Induced Cytokines. Pharmaceutics. 2021 Dec 22; 14 (1)
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  19. Smith C, Crowley A, Munsie M, Behfar A, DeMartino ES, Staff NP, Shapiro SA, Master Z. Academic Physician Specialists' Approaches to Counseling Patients Interested in Unproven Stem Cell and Regenerative Therapies-A Qualitative Analysis. Mayo Clin Proc. 2021 Dec; 96 (12):3086-3096 Epub 2021 Aug 26
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  20. Finnoff JT, Awan TM, Borg-Stein J, Harmon KG, Herman DC, Malanga GA, Master Z, Mautner KR, Shapiro SA. American Medical Society for Sports Medicine Position Statement: Principles for the Responsible Use of Regenerative Medicine in Sports Medicine. Clin J Sport Med. 2021 Nov 1; 31 (6):530-541
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  21. Eliasberg CD, Nemirov DA, Mandelbaum BR, Pearle AD, Tokish JM, Baria MR, Millett PJ, Shapiro SA, Rodeo SA. Complications Following Biologic Therapeutic Injections: A Multicenter Case Series. Arthroscopy. 2021 Aug; 37 (8):2600-2605 Epub 2021 Apr 17
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  22. D'Souza RS, Li L, Leng S, Hunt C, Law L, Muir C, Eldrige J, Bydon M, Chi M, Shapiro S, Mauck WD, Qu W. A three-dimensional computed tomography study to determine the ideal method for fluoroscopically-guided bone marrow aspiration from the iliac crest. Bosn J Basic Med Sci. 2021 Jun 1; 21 (3):370-377 Epub 2021 June 01
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  23. Centeno CJ, Jerome MA, Pastoriza SM, Shapiro S, Mautner K, Malanga GA, DePalma MJ, Mason RA, Stemper I, Dodson E. Use of Bone Marrow Concentrate to Treat Pain and Musculoskeletal Disorders: An Academic Delphi Investigation. Pain Physician. 2021 May; 24 (3):263-273
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  24. Smith C, Crowley A, Munsie M, DeMartino ES, Staff NP, Shapiro S, Master Z. Academic physician specialists' views toward the unproven stem cell intervention industry: areas of common ground and divergence. Cytotherapy. 2021 Apr; 23 (4):348-356 Epub 2021 Feb 06
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  25. Sisti A, Huayllani MT, Restrepo DJ, Boczar D, Manrique OJ, Broer PN, Shapiro SA, Forte AJ. Oil injection for cosmetic enhancement of the upper extremities: a case report and review of literature. Acta Biomed. 2020 Sep 7; 91 (3):e2020082 Epub 2020 Sept 07
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  26. Bruce AJ, Pincelli TP, Heckman MG, Desmond CM, Arthurs JR, Diehl NN, Douglass EJ, Bruce CJ, Shapiro SA. A Randomized, Controlled Pilot Trial Comparing Platelet-Rich Plasma to Topical Minoxidil Foam for Treatment of Androgenic Alopecia in Women. Dermatol Surg. 2020 Jun; 46 (6):826-832
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  27. Manchikanti L, Centeno CJ, Atluri S, Albers SL, Shapiro S, Malanga GA, Abd-Elsayed A, Jerome M, Hirsch JA, Kaye AD, Aydin SM, Beall D, Buford D, Borg-Stein J, Buenaventura RM, Cabaret JA, Calodney AK, Candido KD, Cartier C, Latchaw R, Diwan S, Dodson E, Fausel Z, Fredericson M, Gharibo CG, Gupta M, Kaye AM, Knezevic NN, Kosanovic R, Lucas M, Manchikanti MV, Mason RA, Mautner K, Murala S, Navani A, Pampati V, Pastoriza S, Pasupuleti R, Philip C, Sanapati MR, Sand T, Shah RV, Soin A, Stemper I, Wargo BW, Hernigou P. Bone Marrow Concentrate (BMC) Therapy in Musculoskeletal Disorders: Evidence-Based Policy Position Statement of American Society of Interventional Pain Physicians (ASIPP). Pain Physician. 2020 Mar; 23 (2):E85-E131
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  28. Smith C, Martin-Lillie C, Higano JD, Turner L, Phu S, Arthurs J, Nelson TJ, Shapiro S, Master Z. Challenging misinformation and engaging patients: characterizing a regenerative medicine consult service. Regen Med. 2020 Mar; 15 (3):1427-1440 Epub 2020 Apr 22
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  29. Tian M, Ticer T, Wang Q, Walker S, Pham A, Suh A, Busatto S, Davidovich I, Al-Kharboosh R, Lewis-Tuffin L, Ji B, Quinones-Hinojosa A, Talmon Y, Shapiro S, Rückert F, Wolfram J. Adipose-Derived Biogenic Nanoparticles for Suppression of Inflammation. Small. 2020 Mar; 16(10):e1904064. Epub 2020 Feb 18.
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  30. Rossi LA, Piuzzi NS, Shapiro SA. Glenohumeral Osteoarthritis: The Role for Orthobiologic Therapies: Platelet-Rich Plasma and Cell Therapies. JBJS Rev. 2020 Feb; 8 (2):e0075
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  31. Taliaferro J, Shapiro SA, Montero DP, Shi GG, Wilke BK. Cash-Based Stem-Cell Clinics: The Modern Day Snake Oil Salesman? A Report of Two Cases of Patients Harmed by Intra-articular Stem Cell Injections. JBJS Case Connect. 2019 Dec; 9 (4):e0363
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  32. Shapiro SA, Arthurs JR, Heckman MG, Bestic JM, Kazmerchak SE, Diehl NN, Zubair AC, O'Connor MI. Quantitative T2 MRI Mapping and 12-Month Follow-up in a Randomized, Blinded, Placebo Controlled Trial of Bone Marrow Aspiration and Concentration for Osteoarthritis of the Knees. Cartilage. 2019 Oct; 10 (4):432-443 Epub 2018 Aug 30
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  33. Shapiro SA, Arthurs JR, Heckman MG, Bestic JM, Diehl NN, Zubair AC, O'Connor MI. Response to Letter to the Editor. Cartilage. 2019 Oct; 10 (4):506-507 Epub 2019 July 11
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  34. Suh A, Pham A, Cress MJ, Pincelli T, TerKonda SP, Bruce AJ, Zubair AC, Wolfram J, Shapiro SA. Adipose-derived cellular and cell-derived regenerative therapies in dermatology and aesthetic rejuvenation. Ageing Res Rev. 2019 Sep; 54:100933. Epub 2019 Jun 24.
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  35. Busatto S, Pham A, Suh A, Shapiro S, Wolfram J. Organotropic drug delivery: Synthetic nanoparticles and extracellular vesicles. Biomed Microdevices. 2019 Apr 15; 21(2):46.
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  36. Shapiro SA, Smith CG, Arthurs JR, Master Z. Preparing regenerative therapies for clinical application: proposals for responsible translation. Regen Med. 2019 Feb; 14 (2):77-84 Epub 2019 Jan 17
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  37. Busatto S, Vilanilam G, Ticer T, Lin WL, Dickson DW, Shapiro S, Bergese P, Wolfram J. Tangential Flow Filtration for Highly Efficient Concentration of Extracellular Vesicles from Large Volumes of Fluid. Cells. 2018 Dec 16; 7 (12)
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  38. Arthurs JR, Desmond CM, TerKonda SP, Shapiro SA. Micro-fragmented adipose tissue for treatment of knee osteoarthritis with Baker's cyst: a case study. BMJ Case Rep. 2018 Jun 4; 2018 Epub 2018 June 04
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  39. Shapiro SA, Arthurs JR. Bone marrow aspiration for regenerative orthopedic intervention: technique with ultrasound guidance for needle placement. Regen Med. 2017 Dec; 12 (8):917-928 Epub 2017 Sept 11
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  40. Shapiro SA, Kazmerchak SE, Heckman MG, Zubair AC, O'Connor MI. A Prospective, Single-Blind, Placebo-Controlled Trial of Bone Marrow Aspirate Concentrate for Knee Osteoarthritis. Am J Sports Med. 2017 Jan; 45 (1):82-90 Epub 2016 Sept 30
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  41. Shapiro SA, Hernandez LO, Montero DP. Snapping Pes Anserinus and the Diagnostic Utility of Dynamic Ultrasound. J Clin Imaging Sci. 2017; 7:39 Epub 2017 Oct 17
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  42. Shapiro SA, Alkhamisi A, Pujalte GG. Sonographic Appearance of the Median Nerve Following Revision Carpal Tunnel Surgery. J Clin Imaging Sci. 2016; 6:11 Epub 2016 Mar 30
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  43. Maynard JR, Taylor WC III, McNeil RB, Shapiro SA, Mohseni MM, Vadeboncoeur TF, Silvers SM, Sumrall SV, Perez EA, Diehl NN. Impact of race pace on development of hyponatremia in full- and half-marathoners. S Afr J Med. 2012; 24(2):36-42.
  44. Vadeboncoeur TF, Silvers SM, Taylor WC, Shapiro SA, Roth JA, Diehl N, Mahoney SM, Mohseni MM. Impact of a high body mass index on lower extremity injury in marathon/half-marathon participants. J Phys Act Health. 2012 Jan; 9 (1):96-103
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  45. Mohseni M, Silvers S, McNeil R, Diehl N, Vadeboncoeur T, Taylor W, Shapiro S, Roth J, Mahoney S. Prevalence of hyponatremia, renal dysfunction, and other electrolyte abnormalities among runners before and after completing a marathon or half marathon. Sports Health. 2011 Mar; 3 (2):145-51
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  46. DeOrio JK, Shapiro SA, McNeil RB, Stansel J. Validity of the posterior tibial edema sign in posterior tibial tendon dysfunction. Foot Ankle Int. 2011 Feb; 32(2):189-92.
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  47. Leaseburg JT, DeOrio JK, Shapiro SA. Radiographic correlation of hallux MP fusion position and plate angle. Foot Ankle Int. 2009 Sep; 30: (9)873-6.
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  48. Deorio JK, Leaseburg JT, Shapiro SA. Subtalar distraction arthrodesis through a posterior approach. Foot Ankle Int. 2008 Dec; 29(12):1189-94.
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  49. Kennelly KD, Shapiro SA, Kumar N, Klein CJ, Rubin DI. Spontaneous tibialis anterior tendon rupture: a rare cause of foot drop. Neurology. 2007 May 29; 68(22):1949-51.
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  50. Zapala DA, Shapiro SA, Lundy LB, Leming DT. Simultaneous acute superior nerve neurolabyrinthitis and benign paroxysmal positional vertigo. J Am Acad Audiol. 2006 Jul-Aug; 17 (7):481-6; quiz 531-2
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  51. Shapiro S. Workers' compensation claims related to musculoskeletal injuries Northeast Florida Medicine. 2006; 57(3):41-46.
  52. Shapiro SA, Ejaz AA, Osborne MD, Taylor WC. Moderate exercise-induced hyponatremia. Clin J Sport Med. 2006 Jan; 16 (1):72-3
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  53. Taylor WC, Bourdon J, Zawatsky P, Mills W, Czerkawski J, Lucie S, Kleiner D, Shapiro S, Addeo R. Guidelines for the management of concussion in high school athletes-Jacksonville sports medicine program. Northeast Florida Medicine. 2005 Fall; 44-8.
  54. Watanabe RM, Ghosh S, Langefeld CD, Valle TT, Hauser ER, Magnuson VL, Mohlke KL, Silander K, Ally DS, Chines P, Blaschak-Harvan J, Douglas JA, Duren WL, Epstein MP, Fingerlin TE, Kaleta HS, Lange EM, Li C, McEachin RC, Stringham HM, Trager E, White PP, Balow Jr J, Birznieks G, Chang J, Eldridge W, Erdos MR, Karanjawala ZE, Knapp JI, Kudelko K, Martin C, Morales-Mena A, Musick A, Musick T, Pfahl C, Porter R, Rayman JB, Rha D, Segal L, Shapiro S, et al. The Finland-United States investigation of non-insulin-dependent diabetes mellitus genetics (FUSION) study. II. An autosomal genome scan for diabetes-related quantitative-trait loci. A Multicenter Study. Am J Hum Genet. 2000 Nov; 67(5):1186-200.
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  55. Ghosh S, Watanabe RM, Valle TT, Hauser ER, Magnuson VL, Langefeld CD, Ally DS, Mohlke KL, Silander K, Kohtamaki K, Chines P, Balow Jr J, Birznieks G, Chang J, Eldridge W, Erdos MR, Karanjawala ZE, Knapp JI, Kudelko K, Martin C, Morales-Mena A, Musick A, Musick T, Pfahl C, Porter R, Rayman JB, Rha D, Segal L, Shapiro S, et al. The Finland-United States investigation of non-insulin-dependent diabetes mellitus genetics (FUSION) study. I. An autosomal genome scan for genes that predispose to type 2 diabetes. A Multicenter Study. Am J Hum Genet. 2000; 67(5):1174-85.
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  56. Shapiro S, Stansberry KB, Hill MA, Meyer MD, McNitt PM, Bhatt BA, Vinik AI. Normal blood flow response and vasomotion in the diabetic Charcot foot. J Diabetes Complications. 1999; 12(3):147-53.
  57. Ghosh S, Watanabe RM, Hauser ER, Valle T, Magnuson VL, Erdos MR, Langefeld CD, Balow J Jr, Ally DS, Kohtamaki K, Chines P, Birznieks G, Kaleta HS, Musick A, Te C, Tannenbaum J, Eldridge W, Shapiro S, Martin C, Witt A, So A, Chang J, Shurtleff B, Porter R, Collins FS, Boehnke M, et al. Type 2 diabetes: evidence for linkage on chromosome 20 in716 Finnish affected sib pairs. Proc Natl Acad Sci U S A. 1999; 96(5):2198-203.
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  58. Ghosh S, Hauser ER, Magnuson VL, Valle T, Ally DS, Karanjawala ZE, Rayman JB, Knapp JI, Musick A, Tannenbaum J, Te C, Eldridge W, Shapiro S, Musick T, Martin C, So A, Witt A, Harvan JB, Watanabe RM, Hagopian W, Eriksson J, Nylund SJ, Kohtamaki K, Tuomilehto-Wolf E, Collins FS, Boehnke M, et al. A large sample of Finnish diabetic sib-pairs reveals no evidence for a non-insulin-dependent diabetes mellitus susceptibility locus at 2qter. J Clin Invest. 1998; 102(4):704-9.
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  59. Ghosh S, Karanjawala ZE, Hauser ER, Ally D, Knapp JI, Rayman JB, Musick A, Tannenbaum J, Te C, Shapiro S, Eldridge W, Musick T, Martin C, Smith JR, Carpten JD, Brownstein MJ, Powell JI, Whiten R, Chines P, Nylund SJ, Magnuson VL, Boehnke M, Collins FS. Methods for precise sizing, automated binning of alleles, and reduction of error rates in large-scale genotyping using fluorescently labeled dinucleotide markers. FUSION (Finland-US Investigation of NIDDM Genetics) Study Group. Genome Res. 1997; 7(2):165-78.
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  60. Stansberry KB, Hill MA, Shapiro S, McNitt PM, Bhatt BA, Vinik AI. Impairment of peripheral blood flow responses in diabetes resembles an enhanced aging effect. Diabetes Care. 1997; 20(11):1711-6.
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  61. Stansberry KB, Shapiro S, Hill MA, McNitt PM, Meyer MD, Vinik AI. Impaired peripheral vasomotion in diabetes. Diabetes Care. 1996; 19(7):715-21.
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PST-20223899