Publications Print Macinnis RJ, Jenkins MA, Milne RL, John EM, Daly MB, Andrulis IL, Colonna SV, Phillips KA, Le Marchand L, Newcomb PA, Phipps A, Schmit S, Macrae F, Buchanan D, Gallinger S, Pai RK, Samadder NJ, Giles GG, Southey MC, Hopper JL, Terry MB, Kconfab Investigators. Menopausal hormone therapy: assessing associations with breast and colorectal cancers by familial risk. JNCI Cancer Spectr. 2024 Dec 3 Epub 2024 Dec 03 View PubMed Hazelwood E, Lopez Manzano C, Vincent EE, Albanes D, Bishop DT, Le Marchand L, Ulrich CM, Peters U, Murphy G, Samadder NJ, Anderson L, Gunter MJ, Murphy N, Van Guelpen B, Papadimitriou N. Plasma Ghrelin and Risks of Sex-Specific, Site-Specific, and Early-Onset Colorectal Cancer: A Mendelian Randomization Analysis. Cancer Epidemiol Biomarkers Prev. 2024 Dec 2; 33 (12):1727-1732 View PubMed Hodan R, Gupta S, Weiss JM, Axell L, Burke CA, Chen LM, Chung DC, Clayback KM, Felder S, Foda Z, Giardiello FM, Grady W, Gustafson S, Hagemann A, Hall MJ, Hampel H, Idos G, Joseph N, Kassem N, Katona B, Kelly K, Kieber-Emmons A, Kupfer S, Lang K, Llor X, Markowitz AJ, Prats MM, Niell-Swiller M, Outlaw D, Pirzadeh-Miller S, Samadder NJ, Shibata D, Stanich PP, Swanson BJ, Szymaniak BM, Welborn J, Wiesner GL, Yurgelun MB, Dwyer M, Darlow S, Diwan Z. Genetic/Familial High-Risk Assessment: Colorectal, Endometrial, and Gastric, Version 3.2024, NCCN Clinical Practice Guidelines In Oncology. J Natl Compr Canc Netw. 2024 Dec; 22 (10):695-711 View PubMed Lo CH, Zhao L, Steele EM, Pan CW, Lee JK, Zhang X, Singh H, Samadder NJ. Association of Ultra-processed Food and Unprocessed or Minimally Processed Food Consumption With Bowel Habits Among U.S. Adults. Clin Gastroenterol Hepatol. 2024 Nov; 22 (11):2309-2318.e5 Epub 2024 May 15 View PubMed Choudry MM, Durant AM, Edmonds VS, Warren CJ, Kunze KL, Golafshar MA, Nielsen SM, Esplin ED, Andrews JR, Samadder NJ, Tyson MD. Germline Pathogenic Variants Identified in Patients With Genitourinary Malignancies Undergoing Universal Testing: A Multisite Single-Institution Prospective Study. J Urol. 2024 Oct; 212 (4):590-599 Epub 2024 June 11 View PubMed Siddiqui W, Pacyna JE, Phelan SM, Jones JC, Samadder NJ, Sharp RR. Factors Impacting Intent to Share Multigenic Cancer Testing Results in a Community Hospital Setting. J Pers Med. 2024 Sep 17; 14 (9) Epub 2024 Sept 17 View PubMed Samadder NJ, Gay E, Lindpere V, Bublitz ML, Bandel LA, Armasu SM, Vierkant RA, Ferber MJ, Klee EW, Larson NB, Kruisselbrink TM, Egan JB, Kemppainen JL, Bidwell JS, Anderson JL, McAllister TM, Walker TS, Kunze KL, Golafshar MA, Klint MA, Presutti RJ, Bobo WV, Sekulic A, Summer-Bolster JM, Willman CL, Lazaridis KN. Exome Sequencing Identifies Carriers of the Autosomal Dominant Cancer Predisposition Disorders Beyond Current Practice Guideline Recommendations. JCO Precis Oncol. 2024 Jul; 8:e2400106 View PubMed Khadarian K, Pai R, Samadder NJ. Cronkhite-Canada Syndrome: A Rare Cause of Gastrointestinal Polyposis With Response to Emerging Therapy. ACG Case Rep J. 2024 Apr; 11 (4):e01331 Epub 2024 Apr 05 View PubMed Cornish N, Haycock P, Brenner H, Figueiredo JC, Galesloot TE, Grant RC, Johansson M, Mariosa D, McKay J, Pai R, Pellatt AJ, Samadder NJ, Shi J, Thibord F, Tregouet DA, Voegele C, Thirlwell C, Mumford A, Langdon R, InterLymph Consortium, INVENT-MVP Consortium. Causal relationships between risk of venous thromboembolism and 18 cancers: a bidirectional Mendelian randomization analysis. Int J Epidemiol. 2024 Feb 1; 53 (1) View PubMed Lo CH, Tun KM, Pan CW, Lee JK, Singh H, Samadder NJ. Association Between Social Vulnerability and Gastrointestinal Cancer Mortality in the United States Counties. Gastro Hep Adv. 2024; 3 (6):821-829 Epub 2024 June 07 View PubMed Brake DA, Idler BM, Kunze KL, Golafshar MA, Heald B, Young S, Klint M, Barrus K, Esplin ED, Nussbaum RL, Samadder NJ, Hinni ML, Chang BA. Germline Genetic Testing in Unselected Squamous and Non-Squamous Head and Neck Cancers. Laryngoscope. 2023 Dec; 133 (12):3378-3388 Epub 2023 May 03 View PubMed Bramblet RM, Bakkum-Gamez JN, Slettedahl SW, Foote PH, Taylor WR, Berger CK, Gysbers BJ, Arndt J, Chen L, Doering KA, Burger KN, Mahoney DW, Sherman ME, Kisiel JB, Samadder NJ. Methylated DNA Markers for Sporadic Colorectal and Endometrial Cancer Are Strongly Associated with Lynch Syndrome Cancers. Cancer Prev Res (Phila). 2023 Nov 01; 16(11):611-620. View PubMed Nimptsch K, Aleksandrova K, Pham TT, Papadimitriou N, Janke J, Christakoudi S, Heath A, Olsen A, Tjonneland A, Schulze MB, Katzke V, Kaaks R, van Guelpen B, Harbs J, Palli D, Macciotta A, Pasanisi F, Yohar SMC, Guevara M, Amiano P, Grioni S, Jakszyn PG, Figueiredo JC, Samadder NJ, Li CI, Moreno V, Potter JD, Schoen RE, Um CY, Weiderpass E, Jenab M, Gunter MJ, Pischon T. Prospective and Mendelian randomization analyses on the association of circulating fatty acid binding protein 4 (FABP-4) and risk of colorectal cancer. BMC Med. 2023 Oct 13; 21 (1):391 View PubMed Eslinger C, Walden D, Barry T, Shah S, Samadder NJ, Bekaii-Saab TS. Rechallenge With Switching Immune Checkpoint Inhibitors Following Autoimmune Myocarditis in a Patient With Lynch Syndrome. J Natl Compr Canc Netw. 2023 Sep; 21 (9):894-899 View PubMed Jones JC, Golafshar MA, Coston TW, Rao R, Wysokinska E, Johnson E, Esplin ED, Nussbaum RL, Heald B, Klint M, Barrus K, Uson PL Jr, Nguyen CC, Colon-Otero G, Bekaii-Saab TS, Dronca R, Kunze KL, Samadder NJ. Universal Genetic Testing vs. Guideline-Directed Testing for Hereditary Cancer Syndromes Among Traditionally Underrepresented Patients in a Community Oncology Program. Cureus. 2023 Apr; 15 (4):e37428 Epub 2023 Apr 11 View PubMed Samadder NJ, Foster N, McMurray RP, Burke CA, Stoffel E, Kanth P, Das R, Cruz-Correa M, Vilar E, Mankaney G, Buttar N, Thirumurthi S, Turgeon DK, Sossenheimer M, Westover M, Richmond E, Umar A, Della'Zanna G, Rodriguez LM, Szabo E, Zahrieh D, Limburg PJ. Phase II trial of weekly erlotinib dosing to reduce duodenal polyp burden associated with familial adenomatous polyposis. Gut. 2023 Feb; 72 (2):256-263 Epub 2022 May 30 View PubMed Pai RK, Banerjee I, Shivji S, Jain S, Hartman D, Buchanan DD, Jenkins MA, Schaeffer DF, Rosty C, Como J, Phipps AI, Newcomb PA, Burnett-Hartman AN, Le Marchand L, Samadder NJ, Patel B, Swallow C, Lindor NM, Gallinger SJ, Grant RC, Westerling-Bui T, Conner J, Cyr DP, Kirsch R, Pai RK. Quantitative Pathologic Analysis of Digitized Images of Colorectal Carcinoma Improves Prediction of Recurrence-Free Survival. Gastroenterology. 2022 Dec; 163 (6):1531-1546.e8 Epub 2022 Aug 17 View PubMed Uson PLS Jr, Kunze KL, Golafshar MA, Botrus G, Riegert-Johnson D, Boardman L, Borad MJ, Ahn D, Sonbol MB, Kahn A, Klint M, Esplin ED, Nussbaum RL, Stewart AK, Bekaii-Saab T, Samadder NJ. Germline Cancer Testing in Unselected Patients with Gastric and Esophageal Cancers: A Multi-center Prospective Study. Dig Dis Sci. 2022 Nov; 67 (11):5107-5115 Epub 2022 Feb 05 View PubMed Moller P, Seppala T, Dowty JG, Haupt S, Dominguez-Valentin M, Sunde L, Bernstein I, Engel C, Aretz S, Nielsen M, Capella G, Evans DG, Burn J, Holinski-Feder E, Bertario L, Bonanni B, Lindblom A, Levi Z, Macrae F, Winship I, Plazzer JP, Sijmons R, Laghi L, Valle AD, Heinimann K, Half E, Lopez-Koestner F, Alvarez-Valenzuela K, Scott RJ, Katz L, Laish I, Vainer E, Vaccaro CA, Carraro DM, Gluck N, Abu-Freha N, Stakelum A, Kennelly R, Winter D, Rossi BM, Greenblatt M, Bohorquez M, Sheth H, Tibiletti MG, Lino-Silva LS, Horisberger K, Portenkirchner C, Nascimento I, Rossi NT, da Silva LA, Thomas H, Zarand A, Mecklin JP, Pylvanainen K, Renkonen-Sinisalo L, Lepisto A, Peltomaki P, Therkildsen C, Lindberg LJ, Thorlacius-Ussing O, von Knebel Doeberitz M, Loeffler M, Rahner N, Steinke-Lange V, Schmiegel W, Vangala D, Perne C, Huneburg R, de Vargas AF, Latchford A, Gerdes AM, Backman AS, Guillen-Ponce C, Snyder C, Lautrup CK, Amor D, Palmero E, Stoffel E, Duijkers F, Hall MJ, Hampel H, Williams H, Okkels H, Lubinski J, Reece J, Ngeow J, Guillem JG, Arnold J, Wadt K, Monahan K, Senter L, Rasmussen LJ, van Hest LP, Ricciardiello L, Kohonen-Corish MRJ, Ligtenberg MJL, Southey M, Aronson M, Zahary MN, Samadder NJ, Poplawski N, Hoogerbrugge N, Morrison PJ, James P, Lee G, Chen-Shtoyerman R, Ankathil R, Pai R, Ward R, Parry S, Debniak T, John T, van Overeem Hansen T, Caldes T, Yamaguchi T, Barca-Tierno V, Garre P, Cavestro GM, Weitz J, Redler S, Buttner R, Heuveline V, Hopper JL, Win AK, Lindor N, Gallinger S, Le Marchand L, Newcomb PA, Figueiredo J, Buchanan DD, Thibodeau SN, Ten Broeke SW, Hovig E, Nakken S, Pineda M, Duenas N, Brunet J, Green K, Lalloo F, Newton K, Crosbie EJ, Mints M, Tjandra D, Neffa F, Esperon P, Kariv R, Rosner G, Pavicic WH, Kalfayan P, Torrezan GT, Bassaneze T, Martin C, Moslein G, Ahadova A, Kloor M, Sampson JR, Jenkins MA, European Hereditary Tumour Group (EHTG) and the International Mismatch Repair Consortium (IMRC). Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium. Hered Cancer Clin Pract. 2022 Oct 1; 20 (1):36 Epub 2022 Oct 01 View PubMed Esplin ED, Nielsen SM, Bristow SL, Garber JE, Hampel H, Rana HQ, Samadder NJ, Shore ND, Nussbaum RL. Universal Germline Genetic Testing for Hereditary Cancer Syndromes in Patients With Solid Tumor Cancer. JCO Precis Oncol. 2022 Sep; 6:e2100516 View PubMed Balaguer F, Stoffel EM, Burke CA, Dekker E, Samadder NJ, Van Cutsem E, Lynch PM, Wise PE, Huneburg R, Lim RM, Boytim ML, Du W, Bruckheimer EM, Cohen A, Church J, FAP-310 Investigators. Combination of Sulindac and Eflornithine Delays the Need for Lower Gastrointestinal Surgery in Patients With Familial Adenomatous Polyposis: Post Hoc Analysis of a Randomized Clinical Trial. Dis Colon Rectum. 2022 Apr 1; 65 (4):536-545 View PubMed Uson Junior PL, Kunze KL, Golafshar MA, Riegert-Johnson D, Boardman L, Borad MJ, Ahn D, Sonbol MB, Faigel DO, Fukami N, Pannala R, Barrus K, Mountjoy L, Esplin ED, Nussbaum RL, Stewart AK, Bekaii-Saab T, Samadder NJ. Germline Cancer Susceptibility Gene Testing in Unselected Patients with Hepatobiliary Cancers: A Multi-Center Prospective Study. Cancer Prev Res (Phila). 2022 Feb; 15 (2):121-128 Epub 2021 Nov 15 View PubMed Hansen TM, Nugent Z, Bernstein CN, Samadder NJ, Murthy SK, Singh H. Characteristics of colorectal cancer and use of colonoscopy before colorectal cancer diagnosis among individuals with inflammatory bowel disease: A population-based study. PLoS One. 2022; 17 (8):e0272158 Epub 2022 Aug 01 View PubMed Kang JH, Evans N, Singh S, Samadder NJ, Lee JK. Systematic review with meta-analysis: the prevalence of post-colonoscopy colorectal cancers using the World Endoscopy Organization nomenclature. Aliment Pharmacol Ther. 2021 Nov; 54 (10):1232-1242 Epub 2021 Sept 29 View PubMed Golafshar MA, Petersen M, Vargas CE, Samadder NJ, Kunze KL, McCormick N, Watkin SA, Maleyeva D, Cheng TW, Vargas M, DeWees TA. Utilizing open-source platforms to build and deploy interactive patient-reported quality of life tracking tools for monitoring protocol adherence. Qual Life Res. 2021 Nov; 30 (11):3189-3197 Epub 2020 Sept 09 View PubMed Weiss JM, Gupta S, Burke CA, Axell L, Chen LM, Chung DC, Clayback KM, Dallas S, Felder S, Gbolahan O, Giardiello FM, Grady W, Hall MJ, Hampel H, Hodan R, Idos G, Kanth P, Katona B, Lamps L, Llor X, Lynch PM, Markowitz AJ, Pirzadeh-Miller S, Samadder NJ, Shibata D, Swanson BJ, Szymaniak BM, Wiesner GL, Wolf A, Yurgelun MB, Zakhour M, Darlow SD, Dwyer MA, Campbell M. NCCN Guidelines(R) Insights: Genetic/Familial High-Risk Assessment: Colorectal, Version 1.2021. J Natl Compr Canc Netw. 2021 Oct 15; 19 (10):1122-1132 View PubMed Uson PLS Jr, Samadder NJ, Riegert-Johnson D, Boardman L, Borad MJ, Ahn D, Sonbol MB, Faigel DO, Fukami N, Pannala R, Kunze K, Golafshar M, Klint M, Esplin ED, Nussbaum RL, Stewart AK, Bekaii-Saab T. Clinical Impact of Pathogenic Germline Variants in Pancreatic Cancer: Results From a Multicenter, Prospective, Universal Genetic Testing Study. Clin Transl Gastroenterol. 2021 Oct 8; 12 (10):e00414 Epub 2021 Oct 08 View PubMed Stuttgen Finn K, Pacyna JE, Tsou C, Samadder NJ, Sharp RR. Factors that Influence Intent to Share Genetic Information Related to Cancer Risk with Family Members. J Health Commun. 2021 Aug 03; 26(8):545-552. Epub 2021 Sep 02. View PubMed Esplin ED, Samadder NJ. Universal Genetic Testing to Identify Pathogenic Germline Variants in Patients With Cancer-Reply. JAMA Oncol 2021 Jul 1; 7 (7):1071-1072 View PubMed Reyes-Uribe L, Wu W, Gelincik O, Bommi PV, Francisco-Cruz A, Solis LM, Lynch PM, Lim R, Stoffel EM, Kanth P, Samadder NJ, Mork ME, Taggart MW, Milne GL, Marnett LJ, Vornik L, Liu DD, Revuelta M, Chang K, You YN, Kopelovich L, Wistuba II, Lee JJ, Sei S, Shoemaker RH, Szabo E, Richmond E, Umar A, Perloff M, Brown PH, Lipkin SM, Vilar E. Naproxen chemoprevention promotes immune activation in Lynch syndrome colorectal mucosa. Gut. 2021 Mar; 70 (3):555-566 Epub 2020 July 08 View PubMed Samadder NJ, Riegert-Johnson D, Boardman L, Rhodes D, Wick M, Okuno S, Kunze KL, Golafshar M, Uson PLS Jr, Mountjoy L, Ertz-Archambault N, Patel N, Rodriguez EA, Lizaola-Mayo B, Lehrer M, Thorpe CS, Yu NY, Esplin ED, Nussbaum RL, Sharp RR, Azevedo C, Klint M, Hager M, Macklin-Mantia S, Bryce AH, Bekaii-Saab TS, Sekulic A, Stewart AK. Comparison of Universal Genetic Testing vs Guideline-Directed Targeted Testing for Patients With Hereditary Cancer Syndrome. JAMA Oncol. 2021 Feb 1; 7 (2):230-237 View PubMed Mezina A, Philips N, Bogus Z, Erez N, Xiao R, Fan R, Olthoff KM, Reddy KR, Samadder NJ, Nielsen SM, Hatchell KE, Esplin ED, Rustgi AK, Katona BW, Hoteit MA, Nathanson KL, Wangensteen KJ. Multigene Panel Testing in Individuals With Hepatocellular Carcinoma Identifies Pathogenic Germline Variants. JCO Precis Oncol. 2021; 5 Epub 2021 June 10 View PubMed Boardman LA, Vilar E, You YN, Samadder J. AGA Clinical Practice Update on Young Adult-Onset Colorectal Cancer Diagnosis and Management: Expert Review. Clin Gastroenterol Hepatol. 2020 Oct; 18 (11):2415-2424 Epub 2020 June 07 View PubMed Burke CA, Dekker E, Lynch P, Samadder NJ, Balaguer F, Huneburg R, Burn J, Castells A, Gallinger S, Lim R, Stoffel EM, Gupta S, Henderson A, Kallenberg FG, Kanth P, Roos VH, Ginsberg GG, Sinicrope FA, Strassburg CP, Van Cutsem E, Church J, Lalloo F, Willingham FF, Wise PE, Grady WM, Ford M, Weiss JM, Gryfe R, Rustgi AK, Syngal S, Cohen A. Eflornithine plus Sulindac for Prevention of Progression in Familial Adenomatous Polyposis. N Engl J Med. 2020 Sep 10; 383 (11):1028-1039 View PubMed Macklin-Mantia SK, Hines SL, Chaichana KL, Donaldson AM, Ko SL, Zhai Q, Samadder NJ, Riegert-Johnson DL. Case report expanding the germline AXIN2- related phenotype to include olfactory neuroblastoma and gastric adenoma. BMC Med Genet. 2020 Aug 17; 21 (1):161 View PubMed Samadder NJ, Smith KR, Wong J, Burt RW, Curtin K. Colorectal cancer in the setting of pregnancy and familial risk. Int J Colorectal Dis. 2020 Aug; 35 (8):1559-1566 Epub 2020 May 09 View PubMed Kolb JM, Ahnen DJ, Samadder NJ. Evidenced-Based Screening Strategies for a Positive Family History. Gastrointest Endosc Clin N Am. 2020 Jul; 30 (3):597-609 Epub 2020 Apr 14 View PubMed Bajaj JS, Brenner DM, Cai Q, Cash BD, Crowell M, DiBaise J, Gallegos-Orozco JF, Gardner TB, Gyawali CP, Ha C, Holtmann G, Jamil LH, Kaplan GG, Karsan HA, Kinoshita Y, Lebwohl B, Leontiadis GI, Lichtenstein GR, Longstreth GF, Muthusamy VR, Oxentenko AS, Pimentel M, Pisegna JR, Rubenstein JH, Russo MW, Saini SD, Samadder NJ, Shaukat A, Simren M, Stevens T, Valdovinos M, Vargas H, Spiegel B, Lacy BE. Major Trends in Gastroenterology and Hepatology Between 2010 and 2019: An Overview of Advances From the Past Decade Selected by the Editorial Board of The American Journal of Gastroenterology. Am J Gastroenterol. 2020 Jul; 115 (7):1007-1018 View PubMed Bajaj JS, Brenner DM, Cai Q, Cash BD, Crowell M, DiBaise J, Gallegos-Orozco JF, Gardner TB, Gyawali CP, Ha C, Holtmann G, Jamil LH, Kaplan GG, Karsan HA, Kinoshita Y, Lebwohl B, Leontiadis GI, Lichtenstein GR, Longstreth GF, Muthusamy VR, Oxentenko AS, Pimentel M, Pisegna JR, Rubenstein JH, Russo MW, Saini SD, Samadder NJ, Shaukat A, Simren M, Stevens T, Valdovinos M, Vargas H, Spiegel B, Lacy BE. Major Trends in Gastroenterology and Hepatology Between 2010 and 2019: An Overview of Advances From the Past Decade Selected by the Editorial Board of The American Journal of Gastroenterology. Am J Gastroenterol. 2020 Jun 23 Epub 2020 June 23 View PubMed Yang J, Gurudu SR, Koptiuch C, Agrawal D, Buxbaum JL, Abbas Fehmi SM, Fishman DS, Khashab MA, Jamil LH, Jue TL, Law JK, Lee JK, Naveed M, Qumseya BJ, Sawhney MS, Thosani N, Wani SB, Samadder NJ. American Society for Gastrointestinal Endoscopy guideline on the role of endoscopy in familial adenomatous polyposis syndromes. Gastrointest Endosc. 2020 May; 91 (5):963-982.e2 Epub 2020 Mar 10 View PubMed Decker KM, Lambert P, Nugent Z, Biswanger N, Samadder J, Singh H. Time Trends in the Diagnosis of Colorectal Cancer With Obstruction, Perforation, and Emergency Admission After the Introduction of Population-Based Organized Screening. JAMA Netw Open. 2020 May 1; 3 (5):e205741 Epub 2020 May 01 View PubMed Jackson N, Lidner T, Samadder NJ. Metastatic Lung Cancer Presenting With Jejunal Intussusception And Gastrointestinal Bleeding. Clin Gastroenterol Hepatol. 2020 Mar; 18 (3):e35 Epub 2018 Nov 28 View PubMed Hawkins ML, Blackburn BE, Rowe K, Snyder J, Deshmukh VG, Newman M, Fraser A, Smith K, Herget K, Ganz PA, Samadder NJ, Hashibe M. Endocrine and Metabolic Diseases Among Colorectal Cancer Survivors in a Population-Based Cohort. J Natl Cancer Inst. 2020 Jan 1; 112 (1):78-86 View PubMed Kastrinos F, Samadder NJ, Burt RW. Use of Family History and Genetic Testing to Determine Risk of Colorectal Cancer. Gastroenterology. 2020 Jan; 158 (2):389-403 Epub 2019 Nov 21 View PubMed Samadder NJ, Neklason D, Snow A, Samowitz W, Cessna MH, Rowe K, Sandhu I, Boucher K, Pappas L, Smith KR, Wong J, Curtin K, Provenzale D, Burt RW. Clinical and Molecular Features of Post-Colonoscopy Colorectal Cancers. Clin Gastroenterol Hepatol. 2019 Dec; 17 (13):2731-2739.e2 Epub 2019 Mar 29 View PubMed Kohli DR, Smith KR, Wong J, Yu Z, Boucher K, Faigel DO, Pannala R, Burt RW, Curtin K, Samadder NJ. Familial pancreatic cancer risk: a population-based study in Utah. J Gastroenterol. 2019 Dec; 54 (12):1106-1112 Epub 2019 June 25 View PubMed Jain A, Shafer L, Rothenmund H, Kim CA, Samadder J, Gupta S, Singh H. Suboptimal Adherence in Clinical Practice to Guidelines Recommendation to Screen for Lynch Syndrome. Dig Dis Sci. 2019 Dec; 64 (12):3489-3501 Epub 2019 June 11 View PubMed Kidambi TD, Kohli DR, Samadder NJ, Singh A. Hereditary Polyposis Syndromes. Curr Treat Options Gastroenterol. 2019 Dec; 17 (4):650-665 View PubMed Wilkinson AN, Lieberman D, Leontiadis GI, Tse F, Barkun AN, Abou-Setta A, Marshall JK, Samadder J, Singh H, Telford JJ, Tinmouth J, Leddin D. Colorectal cancer screening for patients with a family history of colorectal cancer or adenomas. Can Fam Physician. 2019 Nov; 65 (11):784-789 View PubMed Samadder NJ, Valentine JF, Guthery S, Singh H, Bernstein CN, Leighton JA, Wan Y, Wong J, Boucher K, Pappas L, Rowe K, Burt RW, Curtin K, Smith KR. Family History Associates With Increased Risk of Colorectal Cancer in Patients With Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol. 2019 Aug; 17 (9):1807-1813.e1 Epub 2018 Sept 26 View PubMed Samadder NJ, Giridhar KV, Baffy N, Riegert-Johnson D, Couch FJ. Hereditary Cancer Syndromes-A Primer on Diagnosis and Management: Part 1: Breast-Ovarian Cancer Syndromes. Mayo Clin Proc. 2019 Jun; 94 (6):1084-1098 View PubMed Samadder NJ, Baffy N, Giridhar KV, Couch FJ, Riegert-Johnson D. Hereditary Cancer Syndromes-A Primer on Diagnosis and Management, Part 2: Gastrointestinal Cancer Syndromes. Mayo Clin Proc. 2019 Jun; 94 (6):1099-1116 View PubMed Lloyd S, Baraghoshi D, Tao R, Garrido-Laguna I, Gilcrease GW 3rd, Whisenant J, Weis JR, Scaife C, Pickron TB, Huang LC, Monroe MM, Abdelaziz S, Fraser AM, Smith KR, Deshmukh V, Newman M, Rowe KG, Snyder J, Samadder NJ, Hashibe M. Mental Health Disorders are More Common in Colorectal Cancer Survivors and Associated With Decreased Overall Survival. Am J Clin Oncol. 2019 Apr; 42(4):355-362. View PubMed Leddin D, Lieberman DA, Tse F, Barkun AN, Abou-Setta AM, Marshall JK, Samadder NJ, Singh H, Telford JJ, Tinmouth J, Wilkinson AN, Leontiadis GI. Clinical Practice Guideline on Screening for Colorectal Cancer in Individuals With a Family History of Nonhereditary Colorectal Cancer or Adenoma: The Canadian Association of Gastroenterology Banff Consensus. Gastroenterology. 2018 Nov; 155 (5):1325-1347.e3 Epub 2018 Aug 16 View PubMed Sample DC, Samadder NJ, Pappas LM, Boucher KM, Samowitz WS, Berry T, Westover M, Nathan D, Kanth P, Byrne KR, Burt RW, Neklason DW. Variables affecting penetrance of gastric and duodenal phenotype in familial adenomatous polyposis patients. BMC Gastroenterol. 2018 Jul 16; 18 (1):115 Epub 2018 July 16 View PubMed Samadder NJ, Wong J, Curtin K. Misclassification of Upper Tract Urothelial Carcinoma in Patients With Lynch Syndrome-Reply. JAMA Oncol 2018 Jul 1; 4 (7):1010 View PubMed Samadder NJ, Kuwada SK, Boucher KM, Byrne K, Kanth P, Samowitz W, Jones D, Tavtigian SV, Westover M, Berry T, Jasperson K, Pappas L, Smith L, Sample D, Burt RW, Neklason DW. Association of Sulindac and Erlotinib vs Placebo With Colorectal Neoplasia in Familial Adenomatous Polyposis: Secondary Analysis of a Randomized Clinical Trial. JAMA Oncol. 2018 May 1; 4 (5):671-677 View PubMed Delker DA, Wood AC, Snow AK, Samadder NJ, Samowitz WS, Affolter KE, Boucher KM, Pappas LM, Stijleman IJ, Kanth P, Byrne KR, Burt RW, Bernard PS, Neklason DW. Chemoprevention with Cyclooxygenase and Epidermal Growth Factor Receptor Inhibitors in Familial Adenomatous Polyposis Patients: mRNA Signatures of Duodenal Neoplasia. Cancer Prev Res (Phila). 2018 Jan; 11 (1):4-15 Epub 2017 Nov 06 View PubMed Gupta S, Provenzale D, Regenbogen SE, Hampel H, Slavin TP Jr, Hall MJ, Llor X, Chung DC, Ahnen DJ, Bray T, Cooper G, Early DS, Ford JM, Giardiello FM, Grady W, Halverson AL, Hamilton SR, Klapman JB, Larson DW, Lazenby AJ, Lynch PM, Markowitz AJ, Mayer RJ, Ness RM, Samadder NJ, Shike M, Sugandha S, Weiss JM, Dwyer MA, Ogba N. NCCN Guidelines Insights: Genetic/Familial High-Risk Assessment: Colorectal, Version 3.2017. J Natl Compr Canc Netw. 2017 Dec; 15 (12):1465-1475 View PubMed Samadder NJ, Valentine JF, Affolter K. A Rare Cause of Diarrhea and Polyposis. Gastroenterology. 2017 Dec; 153 (6):1490-1491 Epub 2017 Sept 01 View PubMed Samadder NJ, Smith KR, Wong J, Thomas A, Hanson H, Boucher K, Kopituch C, Cannon-Albright LA, Burt RW, Curtin K. Cancer Risk in Families Fulfilling the Amsterdam Criteria for Lynch Syndrome. JAMA Oncol. 2017 Dec 1; 3 (12):1697-1701 View PubMed Samadder NJ, Burt RW, Toydemir RM. Developmental Delay and Colon Polyposis. Gastroenterology. 2017 Oct; 153 (4):908-909 Epub 2017 Sept 04 View PubMed Kanth P, Grimmett J, Champine M, Burt R, Samadder NJ. Hereditary Colorectal Polyposis and Cancer Syndromes: A Primer on Diagnosis and Management. Am J Gastroenterol. 2017 Oct; 112 (10):1509-1525 Epub 2017 Aug 08 View PubMed Samadder NJ, Pappas L, Boucherr KM, Smith KR, Hanson H, Fraser A, Wan Y, Burt RW, Curtin K. Long-Term Colorectal Cancer Incidence After Negative Colonoscopy in the State of Utah: The Effect of Family History. Am J Gastroenterol. 2017 Sep; 112 (9):1439-1447 Epub 2017 July 11 View PubMed Shaco-Levy R, Jasperson KW, Martin K, Samadder NJ, Burt RW, Ying J, Bronner MP. Gastrointestinal Polyposis in Cowden Syndrome. J Clin Gastroenterol. 2017 Aug; 51 (7):e60-e67 View PubMed Nagelhout E, Comarell K, Samadder NJ, Wu YP. Barriers to Colorectal Cancer Screening in a Racially Diverse Population Served by a Safety-Net Clinic. J Community Health. 2017 Aug; 42 (4):791-796 View PubMed Warner EL, Bodson J, Mooney R, Lai D, Samadder NJ, Kepka D. Latinas' Colorectal Cancer Screening Knowledge, Barriers to Receipt, and Feasibility of Home-Based Fecal Immunochemical Testing. J Immigr Minor Health. 2017 Jun 23; View PubMed Rengifo-Cam W, Shepherd HM, Jasperson KW, Samadder NJ, Samowitz W, Tripp SR, Schiffman JD, Kohlmann W. Colon Pathology Characteristics in Li-Fraumeni Syndrome. Clin Gastroenterol Hepatol. 2017 Jun 15; View PubMed Affolter K, Gligorich K, Samadder NJ, Samowitz WS, Curtin K. Feasibility of Large-Scale Identification of Sessile Serrated Polyp Patients Using Electronic Records: A Utah Study. Dig Dis Sci. 2017 Jun; 62 (6):1455-1463 Epub 2017 Mar 17 View PubMed Fowler B, Samadder NJ, Kepka D, Ding Q, Pappas L, Kirchhoff AC. Improvements in Colorectal Cancer Incidence Not Experienced by Nonmetropolitan Women: A Population-Based Study From Utah. J Rural Health. 2017 Apr 20; View PubMed Patel J, Madan A, Gammon A, Sossenheimer M, Samadder NJ. Rare hereditary cause of chronic pancreatitis in a young male: SPINK1 mutation. Pan Afr Med J. 2017; 28:110 Epub 2017 Oct 04 View PubMed Rengifo-Cam W, Jasperson K, Garrido-Laguna I, Colman H, Scaife C, Samowitz W, Samadder NJ. A 30-Year-Old Man with Three Primary Malignancies: A Case of Constitutional Mismatch Repair Deficiency. ACG Case Rep J. 2017; 4:e34. View PubMed Samadder NJ, Smith KR, Wong J, Hanson H, Boucher K, Burt RW, Charlton M, Byrne KR, Gallegos-Orozco JF, Koptiuch C, Curtin K. Familial Risk of Biliary Tract Cancers: A Population-Based Study in Utah. Dig Dis Sci. 2016 Dec; 61 (12):3627-3632 Epub 2016 Sept 21 View PubMed Madhoun MF, Cote GA, Ahlawat SK, Ahmad NA, Buscaglia JM, Calderwood AH, Crockett S, Early DS, Gleeson FC, Gurudu SR, Imperiale TF, Liu JJ, Mosler P, Pannala R, Pfau PR, Romagnuolo J, Samadder J, Sethi A, Shergill AK, Shin EJ, Willingham F, Dominitz JA, ASGE Research Committee. Impact and outcomes of research sponsored by the American Society for Gastrointestinal Endoscopy. Gastrointest Endosc. 2016 Sep; 84 (3):385-391.e2 Epub 2016 June 24 View PubMed Lowery JT, Ahnen DJ, Schroy PC 3rd, Hampel H, Baxter N, Boland CR, Burt RW, Butterly L, Doerr M, Doroshenk M, Feero WG, Henrikson N, Ladabaum U, Lieberman D, McFarland EG, Peterson SK, Raymond M, Samadder NJ, Syngal S, Weber TK, Zauber AG, Smith R. Understanding the contribution of family history to colorectal cancer risk and its clinical implications: A state-of-the-science review. Cancer. 2016 Sep 01; 122 (17):2633-45 Epub 2016 June 03 View PubMed Burke CA, Dekker E, Samadder NJ, Stoffel E, Cohen A. Efficacy and safety of eflornithine (CPP-1X)/sulindac combination therapy versus each as monotherapy in patients with familial adenomatous polyposis (FAP): design and rationale of a randomized, double-blind, Phase III trial. BMC Gastroenterol. 2016 Aug 02; 16 (1):87 View PubMed Provenzale D, Gupta S, Ahnen DJ, Bray T, Cannon JA, Cooper G, David DS, Early DS, Erwin D, Ford JM, Giardiello FM, Grady W, Halverson AL, Hamilton SR, Hampel H, Ismail MK, Klapman JB, Larson DW, Lazenby AJ, Lynch PM, Mayer RJ, Ness RM, Regenbogen SE, Samadder NJ, Shike M, Steinbach G, Weinberg D, Dwyer M, Darlow S. Genetic/Familial High-Risk Assessment: Colorectal Version 1.2016, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2016 Aug; 14 (8):1010-30 View PubMed Samadder NJ, Neklason DW, Boucher KM, Byrne KR, Kanth P, Samowitz W, Jones D, Tavtigian SV, Done MW, Berry T, Jasperson K, Pappas L, Smith L, Sample D, Davis R, Topham MK, Lynch P, Strait E, McKinnon W, Burt RW, Kuwada SK. Effect of Sulindac and Erlotinib vs Placebo on Duodenal Neoplasia in Familial Adenomatous Polyposis: A Randomized Clinical Trial. JAMA. 2016 Mar 22-29; 315 (12):1266-75 View PubMed Shaco-Levy R, Jasperson KW, Martin K, Samadder NJ, Burt RW, Ying J, Bronner MP. Morphologic characterization of hamartomatous gastrointestinal polyps in Cowden syndrome, Peutz-Jeghers syndrome, and juvenile polyposis syndrome. Hum Pathol. 2016 Mar; 49:39-48. View PubMed Samadder NJ, Smith KR, Hanson H, Pimentel R, Wong J, Boucher K, Akerley W, Gilcrease G, Ulrich CM, Burt RW, Curtin K. Familial Risk in Patients With Carcinoma of Unknown Primary. JAMA Oncol. 2016 Mar; 2 (3):340-6 View PubMed Samadder NJ, Curtin K, Pappas L, Boucher K, Mineau GP, Smith K, Fraser A, Wan Y, Provenzale D, Kinney AY, Ulrich C, Burt RW. Risk of Incident Colorectal Cancer and Death After Colonoscopy: A Population-based Study in Utah. Clin Gastroenterol Hepatol. 2016 Feb; 14 (2):279-86.e1-2 Epub 2015 Sept 04 View PubMed Samadder NJ, Smith KR, Hanson H, Pimentel R, Wong J, Boucher K, Ahnen D, Singh H, Ulrich CM, Burt RW, Curtin K. Increased Risk of Colorectal Cancer Among Family Members of All Ages, Regardless of Age of Index Case at Diagnosis. Clin Gastroenterol Hepatol. 2015 Dec; 13 (13):2305-11.e1-2 Epub 2015 July 16 View PubMed Tillmans LS, Vierkant RA, Wang AH, Samadder NJ, Lynch CF, Anderson KE, French AJ, Haile RW, Harnack LJ, Potter JD, Slager SL, Smyrk TC, Thibodeau SN, Cerhan JR, Limburg PJ. Associations between Environmental Exposures and Incident Colorectal Cancer by ESR2 Protein Expression Level in a Population-Based Cohort of Older Women. Cancer Epidemiol Biomarkers Prev. 2015 Apr; 24 (4):713-9 Epub 2015 Feb 03 View PubMed Singh H, Bernstein CN, Samadder JN, Ahmed R. Screening rates for colorectal cancer in Canada: a cross-sectional study. CMAJ Open. 2015 Apr-Jun; 3 (2):E149-57 Epub 2015 Apr 02 View PubMed Samadder NJ, Jasperson K, Burt RW. Hereditary and common familial colorectal cancer: evidence for colorectal screening. Dig Dis Sci. 2015 Mar; 60 (3):734-47 Epub 2014 Dec 12 View PubMed Samadder NJ, Smith KR, Mineau GP, Pimentel R, Wong J, Boucher K, Pappas L, Singh H, Ahnen D, Burt RW, Curtin K. Familial colorectal cancer risk by subsite of primary cancer: a population-based study in Utah. Aliment Pharmacol Ther. 2015 Mar; 41 (6):573-80 Epub 2015 Jan 21 View PubMed Samadder NJ, Curtin K, Wong J, Tuohy TM, Mineau GP, Smith KR, Pimentel R, Pappas L, Boucher K, Garrido-Laguna I, Provenzale D, Burt RW. Epidemiology and familial risk of synchronous and metachronous colorectal cancer: a population-based study in Utah. Clin Gastroenterol Hepatol. 2014 Dec; 12 (12):2078-84.e1-2 Epub 2014 Apr 24 View PubMed Samadder NJ, Curtin K, Tuohy TM, Rowe KG, Mineau GP, Smith KR, Pimentel R, Wong J, Boucher K, Burt RW. Increased risk of colorectal neoplasia among family members of patients with colorectal cancer: a population-based study in Utah. Gastroenterology. 2014 Oct; 147 (4):814-821.e5; quiz e15-6 Epub 2014 July 17 View PubMed Singh S, Singh PP, Murad MH, Singh H, Samadder NJ. Prevalence, risk factors, and outcomes of interval colorectal cancers: a systematic review and meta-analysis. Am J Gastroenterol. 2014 Sep; 109 (9):1375-89 Epub 2014 June 24 View PubMed Samadder NJ, Curtin K, Tuohy TM, Pappas L, Boucher K, Provenzale D, Rowe KG, Mineau GP, Smith K, Pimentel R, Kirchhoff AC, Burt RW. Characteristics of missed or interval colorectal cancer and patient survival: a population-based study. Gastroenterology. 2014 Apr; 146 (4):950-60 Epub 2014 Jan 11 View PubMed Jensen JD, King AJ, Carcioppolo N, Krakow M, Samadder NJ, Morgan S. Comparing tailored and narrative worksite interventions at increasing colonoscopy adherence in adults 50-75: a randomized controlled trial. Soc Sci Med. 2014 Mar; 104:31-40. View PubMed Tuohy TM, Rowe KG, Mineau GP, Pimentel R, Burt RW, Samadder NJ. Risk of colorectal cancer and adenomas in the families of patients with adenomas: a population-based study in Utah. Cancer. 2014 Jan 01; 120 (1):35-42 Epub 2013 Oct 21 View PubMed Jasperson KW, Kanth P, Kirchhoff AC, Huismann D, Gammon A, Kohlmann W, Burt RW, Samadder NJ. Serrated polyposis: colonic phenotype, extracolonic features, and familial risk in a large cohort. Dis Colon Rectum. 2013 Nov; 56 (11):1211-6 View PubMed Johnson JB, Affolter KE, Samadder NJ. A rare cause of hematochezia: colon mucormycosis. Clin Gastroenterol Hepatol. 2013 Aug; 11 (8):A22 Epub 2012 Aug 28 View PubMed Samadder NJ, Vierkant RA, Tillmans LS, Wang AH, Weisenberger DJ, Laird PW, Lynch CF, Anderson KE, French AJ, Haile RW, Potter JD, Slager SL, Smyrk TC, Thibodeau SN, Cerhan JR, Limburg PJ. Associations between colorectal cancer molecular markers and pathways with clinicopathologic features in older women. Gastroenterology. 2013 Aug; 145 (2):348-56.e1-2 Epub 2013 May 07 View PubMed Anderson AE, Henry KA, Samadder NJ, Merrill RM, Kinney AY. Rural vs urban residence affects risk-appropriate colorectal cancer screening. Clin Gastroenterol Hepatol. 2013 May; 11 (5):526-33 Epub 2012 Dec 04 View PubMed Samadder NJ, Gornick M, Everett J, Greenson JK, Gruber SB. Inflammatory bowel disease and familial adenomatous polyposis. J Crohns Colitis. 2013 Apr; 7 (3):e103-7 Epub 2012 July 17 View PubMed Johnson JB, Marsden L, Samadder NJ. A rare cause of diarrhea: pancreatic VIPoma. Endoscopy. 2013; 45 Suppl 2 UCTN:E311-2. View PubMed Doycheva I, Tanner S, Zhou D, Samadder NJ. A rare cause of gastric malignancy: Burkitt's lymphoma. Endoscopy. 2013; 45 Suppl 2 UCTN:E432-3. View PubMed Samadder NJ, Bonin EA, Buttar NS, Baron TH, Gostout CJ, Topazian MD, Song LM. Placement of a covered stent for palliation of a cavitated colon cancer by using a novel over-the-scope technique (with video). Gastrointest Endosc. 2012 Dec; 76 (6):1275-7 Epub 2012 Mar 07 View PubMed Samadder NJ, Jasperson K, Burt RW. A pain in the neck and colon polyps. Gastroenterology. 2012 May; 142 (5):1073, 1259 Epub 2012 Mar 19 View PubMed Samadder NJ, Vierkant RA, Tillmans LS, Wang AH, Lynch CF, Anderson KE, French AJ, Haile RW, Harnack LJ, Potter JD, Slager SL, Smyrk TC, Thibodeau SN, Cerhan JR, Limburg PJ. Cigarette smoking and colorectal cancer risk by KRAS mutation status among older women. Am J Gastroenterol. 2012 May; 107 (5):782-9 Epub 2012 Feb 21 View PubMed Gupta A, Samadder J, Elliott E, Sethi S, Schoenfeld P. Prevalence of adenomas and advanced adenomas in patients in the 40- to 49-year age group undergoing screening colonoscopy because of a family history of adenoma/polyp in a first-degree relative. Gastrointest Endosc. 2012 Apr; 75 (4):705-11 View PubMed Samadder NJ, Fang J, Adler DG, Sklow B. Fistulization of self-expanding metal stent from right colon into duodenum. Endoscopy. 2012; 44 Suppl 2 UCTN:E233. View PubMed Gupta AK, Samadder J, Elliott E, Sethi S, Schoenfeld P. Prevalence of any size adenomas and advanced adenomas in 40- to 49-year-old individuals undergoing screening colonoscopy because of a family history of colorectal carcinoma in a first-degree relative. Gastrointest Endosc. 2011 Jul; 74 (1):110-8 Epub 2011 Apr 23 View PubMed Samadder NJ, Mukherjee B, Huang SC, Ahn J, Rennert HS, Greenson JK, Rennert G, Gruber SB. Risk of colorectal cancer in self-reported inflammatory bowel disease and modification of risk by statin and NSAID use. Cancer. 2011 Apr 15; 117 (8):1640-8 Epub 2010 Nov 08 View PubMed PST-20415666 Home Publications