Publications Print Herchko SM, Rutenberg MS, Beltran CJ, Yaddanapudi S. Technical note: A comparison of in-house 3D-printed and commercially available patient-specific skin collimators for use with electron beam therapy. J Appl Clin Med Phys. 2024 May; 25 (5):e14366 Epub 2024 Apr 26 View PubMed O'Dell WG, Siva Kumar S, Klassen CL, Rutenberg MS, Mailhot Vega RB, Mendenhall NP, Okunieff PG, Bradley JA. Measuring early changes in heart function due to radiation treatment in breast cancer patients. Am Heart J Plus. 2024 Feb; 38:100349 Epub 2023 Nov 24 View PubMed Bush A, Herchko S, Chellini A, Orande C, Harrell A, Wear M, Rutenberg M, Attia A, Trifiletti D, Peterson J, May B, Vallow L, Hoppe B. Prompt Pain Relief From Bone Metastases: The Virtual Simulation Program. Adv Radiat Oncol. 2024 Feb; 9 (2):101361 Epub 2023 Aug 25 View PubMed Holtzman AL, Seidensaal K, Iannalfi A, Kim KH, Koto M, Yang WC, Shiau CY, Mahajan A, Ahmed SK, Trifiletti DM, Peterson JL, Koffler DM, Vallow LA, Hoppe BS, Rutenberg MS. Carbon Ion Radiotherapy: An Evidence-Based Review and Summary Recommendations of Clinical Outcomes for Skull-Base Chordomas and Chondrosarcomas. Cancers (Basel). 2023 Oct 17; 15 (20) View PubMed Elhariri A, Alhaj A, Ahn D, Sonbol MB, Bekaii-Saab T, Wu C, Rutenberg MS, Stauffer J, Starr J, Majeed U, Jones J, Borad M, Babiker H. Targeting KRAS in pancreatic adenocarcinoma: Progress in demystifying the holy grail. World J Clin Oncol. 2023 Aug 24; 14 (8):285-296 View PubMed Rutenberg MS, Beltran C. Future Perspective: Carbon Ion Radiotherapy for Head and Neck and Skull Base Malignancies. Oral Maxillofac Surg Clin North Am. 2023 Aug; 35 (3):485-492 Epub 2023 Apr 26 View PubMed Rutenberg MS, Hoppe BS, Starr JS, Awad Z, Thomas M, Morris CG, Johnson P, Henderson RH, Jones JC, Gharia B, Bowers S, Wolfsen HC, Krishnan S, Ko SJ, Babiker HM, Nichols RC Jr. Proton Therapy With Concurrent Chemotherapy for Thoracic Esophageal Cancer: Toxicity, Disease Control, and Survival Outcomes. Int J Part Ther. 2023 Winter; 9 (3):18-29 Epub 2022 Dec 19 View PubMed Holtzman AL, Rutenberg MS, De Leo AN, Rao D, Patel J, Morris CG, Indelicato DJ, Mendenhall WM. The incidence of brainstem toxicity following high-dose conformal proton therapy for adult skull-base malignancies. Acta Oncol. 2022 Aug; 61(8):1026-1031. Epub 2022 Jul 27. View PubMed Holtzman AL, Bates JE, Morris CG, Rutenberg MS, Indelicato DJ, Tavanaiepour D, Mendenhall WM. Impact of Type of Treatment Center and Access to Care on Mortality and Survival for Skull Base Chordoma and Chondrosarcoma. J Neurol Surg B Skull Base. 2022 Jun; 83(3):328-338. Epub 2021 Mar 09. View PubMed Rapp Cooper, Rutenberg Michael, Morris CG, Nichols Romaine. Dose Escalated Proton Radiotherapy with Elective Nodal Irradiation and Concomitant Chemotherapy for Unresectable, Borderline Resectable, or Medically Inoperable Pancreatic Cancer: A Phase II Trial. Journal of Gastointestinal Oncology. 2022. View PubMed Rutenberg MS, Holtzman AL, Indelicato DJ, Huh S, Rao D, Fiester PJ, Morris CG, Tavanaiepour D, Amdur RJ. Disease Control after Radiotherapy for Adult Craniopharyngioma: Clinical Outcomes from a Large Single-Institution Series. J Neurooncol. 2022 May; 157(3):425-433. Epub 2022 Mar 12. View PubMed Padgett M, Kharod SM, Mercado CE, Morris CG, Rutenberg MS, Nichols Jr RC. Patterns-of-care disparities among uninsured versus insured patients with anorectal carcinoma referred for radiotherapy at an Urban Safety-Net Hospital Journal of Gastrointestinal Oncology. 2022. View PubMed Lara-Velazquez M, Mehkri Y, Panther E, Hernandez J, Rao D, Fiester P, Makary R, Rutenberg M, Tavanaiepour D, Rahmathulla G. Current Advances in the Management of Adult Craniopharyngiomas. Curr Oncol. 2022 Mar 04; 29(3):1645-1671. View PubMed Looi WS, Bradley JA, Liang X, Shaw CM, Leyngold M, Mailhot Vega RB, Brooks ED, Rutenberg MS, Spiguel LR, Giap F, Mendenhall NP. Hyperfractionated-Accelerated Reirradiation with Proton Therapy for Radiation-Associated Breast Angiosarcoma. Int J Part Ther. 2022 Spring; 8 (4):55-67 Epub 2022 Jan 18 View PubMed Bolling JP, Dagan R, Rutenberg M, Mamalui-Hunter M, Buskirk SJ, Heckman MG, Hochwald AP, Slopsema R. Treatment of Uveal Melanoma With Radioactive Iodine 125 Implant Compared With Proton Beam Radiotherapy. Mayo Clin Proc Innov Qual Outcomes. 2022 Feb; 6 (1):27-36 Epub 2021 Dec 22 View PubMed Liu IC, Holtzman AL, Rotondo RL, Indelicato DJ, Gururangan S, Cavaliere R, Carter B, Morris CG, Tavanaiepour D, Rutenberg MS. Proton therapy for adult medulloblastoma: Acute toxicity and disease control outcomes. J Neurooncol. 2021 Jul; 153(3):467-476. Epub 2021 Jun 08. View PubMed Holtzman AL, Rotondo RL, Rutenberg MS, Indelicato DJ, De Leo A, Rao D, Patel J, Morris CG, Mendenhall WM. Clinical Outcomes Following Dose-Escalated Proton Therapy for Skull-Base Chordoma. Int J Part Ther. 2021 Summer; 8(1):179-188. Epub 2021 Jun 25. View PubMed De Leo AN, Holtzman AL, Ho MW, Morris CG, Rutenberg MS, Rotondo RL, Bates JE, Indelicato DJ, Rao D, Asa Hasan M, Mendenhall WM. Vision loss following high-dose proton-based radiotherapy for skull-base chordoma and chondrosarcoma. Radiother Oncol. 2021 May; 158:125-130. Epub 2021 Feb 19. View PubMed Lee NCJ, Eskander A, Miccio JA, Park HS, Shah C, Rutenberg M, Hosni A, Husain ZA. Evaluation of head and neck soft tissue sarcoma 8th edition pathologic staging system and proposal of a novel stage grouping system. Oral Oncol. 2021 Mar; 114:105137 Epub 2021 Jan 08 View PubMed Soule E, Baig S, Fiester P, Holtzman A, Rutenberg M, Tavanaiepour D, Rao D. Current Management and Image Review of Skull Base Chordoma: What the Radiologist Needs to Know. J Clin Imaging Sci. 2021; 11:46. Epub 2021 Aug 30. View PubMed Rutenberg MS, Rotondo RL, Rao D, Holtzman AL, Indelicato DJ, Huh S, Morris CG, Mendenhall WM. Clinical outcomes following proton therapy for adult craniopharyngioma: a single-institution cohort study. J Neurooncol. 2020 Apr; 147(2):387-395. Epub 2020 Feb 21. View PubMed Liang X, Bradley JA, Mailhot Vega RB, Rutenberg M, Zheng D, Getman N, Norton KW, Mendenhall N, Li Z. Using Robust Optimization for Skin Flashing in Intensity Modulated Radiation Therapy for Breast Cancer Treatment: A Feasibility Study. Pract Radiat Oncol. 2020 Jan - Feb; 10 (1):59-69 Epub 2019 Oct 15 View PubMed Bekelman JE, Lu H, Pugh S, Baker K, Berg CD, Berrington de Gonzalez A, Braunstein LZ, Bosch W, Chauhan C, Ellenberg S, Fang LC, Freedman GM, Hahn EA, Haffty BG, Khan AJ, Jimenez RB, Kesslering C, Ky B, Lee C, Lu HM, Mishra MV, Mullins CD, Mutter RW, Nagda S, Pankuch M, Powell SN, Prior FW, Schupak K, Taghian AG, Wilkinson JB, MacDonald SM, Cahlon O, RadComp (Radiotherapy Comparative Effectiveness Consortium). Pragmatic randomised clinical trial of proton versus photon therapy for patients with non-metastatic breast cancer: the Radiotherapy Comparative Effectiveness (RadComp) Consortium trial protocol. BMJ Open. 2019 Oct 15; 9 (10):e025556 View PubMed Rao D, Fiester P, Patel J, Rutenberg M, Holtzman A, Dagan R, Rotondo RL, Sandhu SJS. Multidisciplinary Imaging Review Conference Improves Neuro-oncology Radiation Treatment Planning and Follow-up. Cureus. 2019 Oct 10; 11(10):e5882. View PubMed Badiyan SN, Rutenberg MS, Hoppe BS, Mohindra P, Larson G, Hartsell WF, Tsai H, Zeng J, Rengan R, Glass E, Katz S, Vargas C, Feigenberg SJ, Simone CB 2nd. Clinical Outcomes of Patients With Recurrent Lung Cancer Reirradiated With Proton Therapy on the Proton Collaborative Group and University of Florida Proton Therapy Institute Prospective Registry Studies. Pract Radiat Oncol. 2019 Jul - Aug; 9 (4):280-288 Epub 2019 Feb 23 View PubMed Holtzman AL, Rotondo RL, Rutenberg MS, Indelicato DJ, Mercado CE, Rao D, Tavanaiepour D, Morris CG, Louis D, Flampouri S, Mendenhall WM. Proton therapy for skull-base chondrosarcoma, a single-institution outcomes study. J Neurooncol. 2019 May; 142(3):557-563. Epub 2019 Mar 02. View PubMed Liang X, Bradley JA, Zheng D, Rutenberg M, Mailhot Vega R, Mendenhall N, Li Z. The impact of dose algorithms on tumor control probability in intensity-modulated proton therapy for breast cancer. Phys Med. 2019 May; 61:52-57 Epub 2019 May 03 View PubMed Mercado CE, Holtzman AL, Rotondo R, Rutenberg MS, Mendenhall WM. Proton therapy for skull base tumors: A review of clinical outcomes for chordomas and chondrosarcomas. Head Neck. 2019 Feb; 41 (2):536-541 Epub 2018 Dec 07 View PubMed Slopsema RL, Mamalui M, Bolling J, Flampouri S, Yeung D, Li Z, Rutenberg MS, Dagan R. Can CT imaging improve targeting accuracy in clip-based proton therapy of ocular melanoma? Phys Med Biol. 2019 Jan 24; 64(3):035010. View PubMed Liang X, Li Z, Zheng D, Bradley JA, Rutenberg M, Mendenhall N. A comprehensive dosimetric study of Monte Carlo and pencil-beam algorithms on intensity-modulated proton therapy for breast cancer. J Appl Clin Med Phys. 2019 Jan; 20 (1):128-136 Epub 2018 Nov 28 View PubMed Mokhtech M, Morris CG, Indelicato DJ, Rutenberg MS, Amdur RJ. Patterns of Failure in Patients With Adult Medulloblastoma Presenting Without Extraneural Metastasis. Am J Clin Oncol. 2018 Oct; 41 (10):1015-1018 View PubMed Chuong M, Badiyan SN, Yam M, Li Z, Langen K, Regine W, Morris C, Snider J 3rd, Mehta M, Huh S, Rutenberg M, Nichols RC. Pencil beam scanning versus passively scattered proton therapy for unresectable pancreatic cancer. J Gastrointest Oncol. 2018 Aug; 9 (4):687-693 View PubMed Liang X, Bradley JA, Zheng D, Rutenberg M, Yeung D, Mendenhall N, Li Z. Prognostic factors of radiation dermatitis following passive-scattering proton therapy for breast cancer. Radiat Oncol. 2018 Apr 19; 13(1):72. View PubMed Bates JE, Morris CG, Iovino NM, Rutenberg M, Zlotecki RA, Gibbs CP, Scarborough M, Indelicato DJ. Radiation Therapy for Aggressive Fibromatosis: The Association Between Local Control and Age. Int J Radiat Oncol Biol Phys. 2018 Mar 15; 100 (4):997-1003 Epub 2017 Dec 21 View PubMed Zhu S, Rotondo R, Mendenhall WM, Dagan R, Lewis D, Huh S, Knox G, Tavaniepour D, Sandhu S, Rutenberg MS. Long-Term Outcomes of Fractionated Stereotactic Proton Therapy for Vestibular Schwannoma: A Case Series. Int J Part Ther. 2018 Spring; 4 (4):37-46 Epub 2018 July 26 View PubMed Hitchcock KE, Nichols RC, Morris CG, Bose D, Hughes SJ, Stauffer JA, Celinski SA, Johnson EA, Zaiden RA, Mendenhall NP, Rutenberg MS. Feasibility of pancreatectomy following high-dose proton therapy for unresectable pancreatic cancer. World J Gastrointest Surg. 2017 Apr 27; 9 (4):103-108 View PubMed Bradley JA, Ho MW, Li Z, Liang X, Rutenberg M, Dagan R, Mendenhall NP. A Technical Guide for Passive Scattering Proton Radiation Therapy for Breast Cancer. Int J Part Ther. 2017 Spring; 3 (4):473-484 Epub 2017 July 11 View PubMed Rutenberg MS, Meister M, Amin PP, Hussain A, Naslund MJ, Kwok Y. Salvage external beam radiotherapy for locally recurrent prostate cancer after definitive brachytherapy. Brachytherapy. 2016 Nov - Dec; 15 (6):722-729 Epub 2016 Sept 28 View PubMed Dagan R, Bryant CM, Bradley JA, Indelicato DJ, Rutenberg M, Rotondo R, Morris CG, Mendenhall WM. A Prospective Evaluation of Acute Toxicity from Proton Therapy for Targets of the Parotid Region. Int J Part Ther. 2016 Fall; 3 (2):285-290 Epub 2016 Dec 30 View PubMed Bradley JA, Dagan R, Ho MW, Rutenberg M, Morris CG, Li Z, Mendenhall NP. Initial Report of a Prospective Dosimetric and Clinical Feasibility Trial Demonstrates the Potential of Protons to Increase the Therapeutic Ratio in Breast Cancer Compared With Photons. Int J Radiat Oncol Biol Phys. 2016 May 1; 95 (1):411-421 Epub 2015 Sept 25 View PubMed Rutenberg M, Kirwan J, Morris CG, Werning JW, Mendenhall WM. Radiation therapy for sinonasal inverted papilloma. Pract Radiat Oncol. 2013 Oct-Dec; 3 (4):275-81 Epub 2012 Sept 07 View PubMed Fang R, Chen F, Dong Z, Hu D, Barbera AJ, Clark EA, Fang J, Yang Y, Mei P, Rutenberg M, Li Z, Zhang Y, Xu Y, Yang H, Wang P, Simon MD, Zhou Q, Li J, Marynick MP, Li X, Lu H, Kaiser UB, Kingston RE, Xu Y, Shi YG. LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation. Mol Cell. 2013 Feb 7; 49 (3):558-70 Epub 2012 Dec 20 View PubMed Rutenberg MS, Indelicato DJ, Knapik JA, Lagmay JP, Morris C, Zlotecki RA, Scarborough MT, Gibbs CP, Marcus RB. External-beam radiotherapy for pediatric and young adult desmoid tumors. Pediatr Blood Cancer. 2011 Sep; 57 (3):435-42 Epub 2010 Dec 15 View PubMed Fang R, Barbera AJ, Xu Y, Rutenberg M, Leonor T, Bi Q, Lan F, Mei P, Yuan GC, Lian C, Peng J, Cheng D, Sui G, Kaiser UB, Shi Y, Shi YG. Human LSD2/KDM1b/AOF1 regulates gene transcription by modulating intragenic H3K4me2 methylation. Mol Cell. 2010 Jul 30; 39 (2):222-33 View PubMed Tahiliani M, Mei P, Fang R, Leonor T, Rutenberg M, Shimizu F, Li J, Rao A, Shi Y. The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation. Nature. 2007 May 31; 447 (7144):601-5 Epub 2007 Apr 29 View PubMed Fuehrlein BS, Rutenberg MS, Silver JN, Warren MW, Theriaque DW, Duncan GE, Stacpoole PW, Brantly ML. Differential metabolic effects of saturated versus polyunsaturated fats in ketogenic diets. J Clin Endocrinol Metab. 2004 Apr; 89 (4):1641-5 View PubMed PST-20534592 Home Publications