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Aysegul Ozerdem, M.D., Ph.D.

  1. Psychiatrist
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Publications

  1. Singh B, Kung S, Poppe KA, Brown SL, Erickson C, Hale AM, Johnson BL, Jones KL, Pazdernik VK, Schak KM, Betcher HK, Moore KM, Ozerdem A, Veldic M, Frye MA, Bobo WV. Partial wake therapy and luminotherapy as an adjunct to usual care in hospitalized patients with depression - a pilot study. Psychiatry Res 2024 Jul; 337:115921 Epub 2024 Apr 25
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  2. Arat Celik HE, Yilmaz S, Aksahin IC, Kok Kendirlioglu B, Corekli E, Dal Bekar NE, Celik OF, Yorguner N, Targitay Ozturk B, Islekel H, Ozerdem A, Akan P, Ceylan D, Tuna G. Oxidatively-induced DNA base damage and base excision repair abnormalities in siblings of individuals with bipolar disorder DNA damage and repair in bipolar disorder. Transl Psychiatry. 2024 May 24; 14 (1):207
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  3. Ercis M, Ozerdem A, Veldic M, Singh B, Coombes BJ, Biernacka JM, Lazaridis KN, Frye MA. Measuring the exposome in bipolar disorder. Bipolar Disord. 2024 May 1 Epub 2024 May 01
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  4. Ercis M, Sanchez-Ruiz JA, Webb LM, Solares-Bravo M, Betcher HK, Moore KM, Frye MA, Veldic M, Ozerdem A. Sex differences in effectiveness and adverse effects of mood stabilizers and antipsychotics: A systematic review. J Affect Disord. 2024 May 1; 352:171-192 Epub 2024 Feb 15
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  5. Sanchez-Ruiz JA, Coombes BJ, Pazdernik VM, Melhuish Beaupre LM, Jenkins GD, Pendegraft RS, Batzler A, Ozerdem A, McElroy SL, Gardea-Resendez MA, Cuellar-Barboza AB, Prieto ML, Frye MA, Biernacka JM. Clinical and genetic contributions to medical comorbidity in bipolar disorder: a study using electronic health records-linked biobank data. Mol Psychiatry. 2024 Mar 28 [Epub ahead of print]
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  6. Nunez NA, Coombes BJ, Beaupre LM, Ozerdem A, Resendez MG, Romo-Nava F, Bond DJ, Veldic M, Singh B, Moore KM, Betcher HK, Kung S, Prieto ML, Fuentes M, Ercis M, Miola A, Sanchez Ruiz JA, Jenkins G, Batzler A, Leung JG, Cuellar-Barboza A, Tye SJ, McElroy SL, Biernacka JM, Frye MA. Pharmacogenomic overlap between antidepressant treatment response in major depression & antidepressant associated treatment emergent mania in bipolar disorder. Transl Psychiatry. 2024 Feb 13; 14 (1):93
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  7. Miola A, Gardea-Resendez M, Ortiz-Orendain J, Nunez NA, Ercis M, Coombes BJ, Salgado MF, Gruhlke PM, Michel I, Bostwick JM, McKean AJ, Ozerdem A, Frye MA. Factors associated with suicide attempts in the antecedent illness trajectory of bipolar disorder and schizophrenia. Int J Bipolar Disord. 2023 Dec 8; 11 (1):38 Epub 2023 Dec 08
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  8. Ortiz-Orendain J, Gardea-Resendez M, Castiello-de Obeso S, Golebiowski R, Coombes B, Gruhlke PM, Michel I, Bostwick JM, Morgan RJ, Ozerdem A, Frye MA, McKean AJ. Antecedents to first episode psychosis and mania: Comparing the initial prodromes of schizophrenia and bipolar disorder in a retrospective population cohort. J Affect Disord. 2023 Nov 1; 340:25-32 Epub 2023 July 27
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  9. Sanchez-Ruiz JA, Leibman NI, Larson NB, Jenkins GD, Ahmed AT, Nunez NA, Biernacka JM, Winham SJ, Weinshilboum RM, Wang L, Frye MA, Ozerdem A. Age-Dependent Sex Differences in the Prevalence of Selective Serotonin Reuptake Inhibitor Treatment: A Retrospective Cohort Analysis. J Womens Health (Larchmt). 2023 Nov; 32 (11):1229-1240 Epub 2023 Oct 19
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  10. Nunez NA, Coombes BJ, Melhuish Beaupre L, Romo-Nava F, Gardea-Resendez M, Ozerdem A, Veldic M, Singh B, Sanchez Ruiz JA, Cuellar-Barboza A, Leung JG, Prieto ML, McElroy SL, Biernacka JM, Frye MA. Antidepressant-Associated Treatment Emergent Mania: A Meta-Analysis to Guide Risk Modeling Pharmacogenomic Targets of Potential Clinical Value. J Clin Psychopharmacol. 2023 Aug 16; 43 (5):428-33 [Epub ahead of print]
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  11. Miola A, Fountoulakis KN, Baldessarini RJ, Veldic M, Solmi M, Rasgon N, Ozerdem A, Perugi G, Frye MA, Preti A. Prevalence and outcomes of rapid cycling bipolar disorder: Mixed method systematic meta-review. J Psychiatr Res. 2023 Aug; 164:404-415 Epub 2023 June 25
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  12. Romo-Nava F, Blom T, Cuellar-Barboza AB, Barrera FJ, Miola A, Mori NN, Prieto ML, Veldic M, Singh B, Gardea-Resendez M, Nunez NA, Ozerdem A, Biernacka JM, Frye MA, McElroy SL. Clinical characterization of patients with bipolar disorder and a history of asthma: An exploratory study. J Psychiatr Res. 2023 Aug; 164:8-14 Epub 2023 June 03
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  13. Miola A, Alvarez-Villalobos NA, Ruiz-Hernandez FG, De Filippis E, Veldic M, Prieto ML, Singh B, Sanchez Ruiz JA, Nunez NA, Resendez MG, Romo-Nava F, McElroy SL, Ozerdem A, Biernacka JM, Frye MA, Cuellar-Barboza AB. Insulin resistance in bipolar disorder: A systematic review of illness course and clinical correlates. J Affect Disord. 2023 Aug 1; 334:1-11 Epub 2023 Apr 21
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  14. Kumar R, LeMahieu AM, Stan MN, Seshadri A, Ozerdem A, Pazdernik VK, Haynes TL, Daugherty DH 3rd, Sundaresh V, Veldic M, Croarkin PE, Frye MA, Singh B. The Association Between Thyroid Stimulating Hormone and Depression: A Historical Cohort Study. Mayo Clin Proc. 2023 Jul; 98 (7):1009-1020
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  15. Zugman A, Alliende LM, Medel V, Bethlehem RAI, Seidlitz J, Ringlein G, Arango C, Arnatkeviciute A, Asmal L, Bellgrove M, Benegal V, Bernardo M, Billeke P, Bosch-Bayard J, Bressan R, Busatto GF, Castro MN, Chaim-Avancini T, Compte A, Costanzi M, Czepielewski L, Dazzan P, de la Fuente-Sandoval C, Di Forti M, Diaz-Caneja CM, Maria Diaz-Zuluaga A, Du Plessis S, Duran FLS, Fittipaldi S, Fornito A, Freimer NB, Gadelha A, Gama CS, Garani R, Garcia-Rizo C, Gonzalez Campo C, Gonzalez-Valderrama A, Guinjoan S, Holla B, Ibanez A, Ivanovic D, Jackowski A, Leon-Ortiz P, Lochner C, Lopez-Jaramillo C, Luckhoff H, Massuda R, McGuire P, Miyata J, Mizrahi R, Murray R, Ozerdem A, Pan PM, Parellada M, Phahladira L, Ramirez-Mahaluf JP, Reckziegel R, Reis Marques T, Reyes-Madrigal F, Roos A, Rosa P, Salum G, Scheffler F, Schumann G, Serpa M, Stein DJ, Tepper A, Tiego J, Ueno T, Undurraga J, Undurraga EA, Valdes-Sosa P, Valli I, Villarreal M, Winton-Brown TT, Yalin N, Zamorano F, Zanetti MV, Winkler AM, Pine DS, Evans-Lacko S, Crossley NA, cVEDA. Country-level gender inequality is associated with structural differences in the brains of women and men. Proc Natl Acad Sci U S A. 2023 May 16; 120 (20):e2218782120 Epub 2023 May 08
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  16. Sanchez Ruiz JA, Coombes BJ, Pendegraft RS, Ozerdem A, McElroy SL, Cuellar-Barboza AB, Prieto ML, Frye MA, Winham SJ, Biernacka JM. Pharmacotherapy exposure as a marker of disease complexity in bipolar disorder: Associations with clinical & genetic risk factors. Psychiatry Res. 2023 May; 323:115174 Epub 2023 Mar 21
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  17. Ercis M, Ozerdem A, Singh B. When and How to Use Lithium Augmentation for Treating Major Depressive Disorder. J Clin Psychiatry. 2023 Mar 08; 84(2).
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  18. Gardea-Resendez M, Coombes BJ, Veldic M, Tye SJ, Romo-Nava F, Ozerdem A, Prieto ML, Cuellar-Barboza A, Nunez NA, Singh B, Pendegraft RS, Miola A, McElroy SL, Biernacka JM, Morava E, Kozicz T, Frye MA. Antidepressants that increase mitochondrial energetics may elevate risk of treatment-emergent mania. Mol Psychiatry. 2023 Mar; 28 (3):1020-1026 Epub 2022 Dec 13
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  19. Bora E, Verim B, Akgul O, Ildiz A, Ceylan D, Alptekin K, Ozerdem A, Akdede BB. Clinical and developmental characteristics of cognitive subgroups in a transdiagnostic sample of schizophrenia spectrum disorders and bipolar disorder. Eur Neuropsychopharmacol. 2023 Mar; 68:47-56 Epub 2023 Jan 12
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  20. Pahwa M, Kucuker MU, Ho MC, Puspitasari A, Moore KM, Betcher HK, Frye MA, Singh B, Ozerdem A, Veldic M. Cardiometabolic and endocrine comorbidities in women with bipolar disorder: A systematic review. J Affect Disord. 2023 Feb 15; 323:841-859 Epub 2022 Dec 17
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  21. Joseph B, Nunez NA, Pazdernik V, Kumar R, Pahwa M, Ercis M, Ozerdem A, Cuellar-Barboza AB, Romo-Nava F, McElroy SL, Coombes BJ, Biernacka JM, Stan MN, Frye MA, Singh B. Long-Term Lithium Therapy and Thyroid Disorders in Bipolar Disorder: A Historical Cohort Study. Brain Sci. 2023 Jan 12; 13(1).
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  22. Kumar R, Joseph B, Pazdernik VM, Geske J, Nuñez NA, Pahwa M, Kashani KB, Veldic M, Betcher HK, Moore KM, Croarkin PE, Ozerdem A, Cuellar-Barboza AB, McElroy SL, Biernacka JM, Frye MA, Singh B. Real-World Clinical Practice Among Patients With Bipolar Disorder and Chronic Kidney Disease on Long-term Lithium Therapy. J Clin Psychopharmacol. 2023 Jan-Feb 01; 43(1):6-11.
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  23. Ortiz-Orendain J, Gardea-Resendez M, Castiello-de Obeso S, Golebiowski R, Coombes B, Gruhlke PM, Michel I, Bostwick JM, Morgan RJ, Ozerdem A, Frye MA, McKean AJ. Antecedents to first episode psychosis and mania: comparing the initial prodromes of schizophrenia and bipolar disorder in a retrospective population cohort. Journal of Affective Disorders. 2023; 340:25-32
  24. Celik HEA, Kucukgoncu S, Erdogan A, Ozerdem A. Response Inhibition and Interference Control in Adult Attention Deficit Hyperactivity Disorder. Noro Psikiyatr Ars. 2023; 60 (1):3-8 Epub 2023 Feb 26
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  25. Hantsoo L, Jagodnik KM, Novick AM, Baweja R, di Scalea TL, Ozerdem A, McGlade EC, Simeonova DI, Dekel S, Kornfield SL, Nazareth M, Weiss SJ. The role of the hypothalamic-pituitary-adrenal axis in depression across the female reproductive lifecycle: current knowledge and future directions. Front Endocrinol (Lausanne). 2023; 14:1295261 Epub 2023 Dec 12
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  26. Gardea-Resendez M, Ortiz-Orendain J, Miola A, Fuentes Salgado M, Ercis M, Coombes BJ, Gruhlke PM, Bostwick JM, Michel I, Vande Voort JL, Ozerdem A, McKean A, Frye MA, Taylor-Desir M. Racial differences in pathways to care preceding first episode mania or psychosis: a historical cohort prodromal study. Front Psychiatry. 2023; 14:1241071 Epub 2023 Sept 04
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  27. Weiss SJ, Simeonova DI, Koleva H, Muzik M, Clark KD, Ozerdem A, Cooper B, Ammerman RT. Potential paths to suicidal ideation and suicide attempts among high-risk women. J Psychiatr Res. 2022 Nov; 155:493-500 Epub 2022 Sept 22
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  28. Gardea-Resendez M, Winham SJ, Romo-Nava F, Cuellar-Barboza A, Clark MM, Andreazza AC, Cabello-Arreola A, Veldic M, Bond DJ, Singh B, Prieto ML, Nunez NA, Betcher H, Moore KM, Blom T, Colby C, Pendegraft RS, Kelpin SS, Ozerdem A, Miola A, De Filippis E, Biernacka JM, McElroy SL, Frye MA. Quantification of diet quality utilizing the rapid eating assessment for participants-shortened version in bipolar disorder: Implications for prospective depression and cardiometabolic studies. J Affect Disord. 2022 Aug 1; 310:150-155 Epub 2022 May 08
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  29. Kucuker MU, Ozerdem A, Ceylan D, Cabello-Arreola A, Ho AMC, Joseph B, Webb LM, Croarkin PE, Frye MA, Veldic M. The role of base excision repair in major depressive disorder and bipolar disorder. J Affect Disord. 2022 Jun 1; 306:288-300 Epub 2022 Mar 16
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  30. Gardea-Resendez M, Taylor-Desir MJ, Romo-Nava F, Bond D, Vallender EJ, Cuellar-Barboza AB, Prieto ML, Nunez N, Veldic M, Ozerdem A, Singh B, Markota M, Colby CL, Coombes BJ, Biernacka JM, McElroy SL, Frye MA. Clinical Phenotype of Tardive Dyskinesia in Bipolar Disorder. J Clin Psychopharmacol. 2022 Feb 25 [Epub ahead of print]
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  31. de Zwarte SMC, Brouwer RM, Agartz I, Alda M, Alonso-Lana S, Bearden CE, Bertolino A, Bonvino A, Bramon E, Buimer EEL, Cahn W, Canales-Rodriguez EJ, Cannon DM, Cannon TD, Caseras X, Castro-Fornieles J, Chen Q, Chung Y, De la Serna E, Del Mar Bonnin C, Demro C, Di Giorgio A, Doucet GE, Eker MC, Erk S, Fatjo-Vilas M, Fears SC, Foley SF, Frangou S, Fullerton JM, Glahn DC, Goghari VM, Goikolea JM, Goldman AL, Gonul AS, Gruber O, Hajek T, Hawkins EL, Heinz A, Hidiroglu Ongun C, Hillegers MHJ, Houenou J, Hulshoff Pol HE, Hultman CM, Ingvar M, Johansson V, Jonsson EG, Kane F, Kempton MJ, Koenis MMG, Kopecek M, Kramer B, Lawrie SM, Lenroot RK, Marcelis M, Mattay VS, McDonald C, Meyer-Lindenberg A, Michielse S, Mitchell PB, Moreno D, Murray RM, Mwangi B, Nabulsi L, Newport J, Olman CA, van Os J, Overs BJ, Ozerdem A, Pergola G, Picchioni MM, Piguet C, Pomarol-Clotet E, Radua J, Ramsay IS, Richter A, Roberts G, Salvador R, Saricicek Aydogan A, Sarro S, Schofield PR, Simsek EM, Simsek F, Soares JC, Sponheim SR, Sugranyes G, Toulopoulou T, Tronchin G, Vieta E, Walter H, Weinberger DR, Whalley HC, Wu MJ, Yalin N, Andreassen OA, Ching CRK, Thomopoulos SI, van Erp TGM, Jahanshad N, Thompson PM, Kahn RS, van Haren NEM. Intelligence, educational attainment, and brain structure in those at familial high-risk for schizophrenia or bipolar disorder. Hum Brain Mapp. 2022 Jan; 43 (1):414-430 Epub 2020 Oct 07
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  32. Celik HEA, Ceylan D, Bagci B, Akdede BB, Alptekin K, Ozerdem A. Quality of Life of Individuals with Bipolar Disorder and Schizophrenia. Noro Psikiyatr Ars. 2022; 59 (4):309-314 Epub 2022 Nov 10
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  33. Nunez NA, Coombes BJ, Romo-Nava F, Bond DJ, Vande Voort J, Croarkin PE, Leibman N, Gardea Resendez M, Veldic M, Betcher H, Singh B, Colby C, Cuellar-Barboza A, Prieto M, Moore KM, Ozerdem A, McElroy SL, Frye MA, Biernacka JM. Clinical and Genetic Correlates of Bipolar Disorder With Childhood-Onset Attention Deficit Disorder. Front Psychiatry. 2022; 13:884217 Epub 2022 Apr 14
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  34. Romo-Nava F, Blom T, Cuellar-Barboza AB, Awosika OO, Martens BE, Mori NN, Colby CL, Prieto ML, Veldic M, Singh B, Gardea-Resendez M, Nunez NA, Ozerdem A, Biernacka JM, Frye MA, McElroy SL. Revisiting the bipolar disorder with migraine phenotype: Clinical features and comorbidity. J Affect Disord. 2021 Dec 1; 295:156-162 Epub 2021 Aug 23
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  35. Pahwa M, Joseph B, Nunez NA, Jenkins GD, Colby CL, Kashani KB, Marin Veldic Veldic, Marin Veldic Veldic, Moore KM, Betcher HK, Ozerdem A, Cuellar-Barboza AB, McElroy SL, Biernacka JM, Frye MA, Singh B. Long-term lithium therapy and risk of chronic kidney disease in bipolar disorder: A historical cohort study. Bipolar Disord. 2021 Nov; 23 (7):715-723 Epub 2021 Mar 11
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  36. Nunez NA, Sola C, Kung S, Singh B, Ozerdem A, Veldic M, Croarkin PE, Moore KM, Betcher HK, Vande JL, Geske JR, Biernacka JM, Rummans TA, Bahn RS, Frye MA. Deiodinase variation and liothyronine treatment interaction to accelerate ECT response in major depression: Pilot data and implications for thyroid pharmacogenomic testing in mood disorders Personalized Medicine in Psychiatry. 2021; 29-30.
  37. Baykara B, Koc D, Resmi H, Akan P, Tunca Z, Ozerdem A, Ceylan D, Yalcin NG, Binici NC, Guney SA, Mesman E, Hillegers MHJ, Emiroglu NI. Brain-derived neurotrophic factor in bipolar disorder: Associations with age at onset and illness duration. Prog Neuropsychopharmacol Biol Psychiatry. 2021 Jun 8; 108:110075 Epub 2020 Aug 13
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  38. Hu Y, Kung S, Ozerdem A, Vande Voort JL, Singh B, McDonald WM, Riva-Posse P, Frye MA. Hypomania associated with high dose ketamine treatment. Bipolar Disord. 2021 Jun; 23 (4):426-428 Epub 2021 Feb 24
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  39. Celik HEA, Ceylan D, Ongun CH, Erdogan A, Tan D, Gumuskesen P, Bagci B, Ozerdem A. Neurocognitive Functions in Bipolar Disorder in Relation to Comorbid ADHD. Noro Psikiyatr Ars. 2021 Jun; 58 (2):87-93 Epub 2021 Jan 23
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  40. Bora E, Can G, Zorlu N, Ulas G, Inal N, Ozerdem A. Structural dysconnectivity in offspring of individuals with bipolar disorder: The effect of co-existing clinical-high-risk for bipolar disorder. J Affect Disord. 2021 Feb 15; 281:109-116 Epub 2020 Dec 01
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  41. Ceylan D, Akdede BB, Bora E, Aktener AY, Hidiroglu Ongun C, Tunca Z, Alptekin K, Ozerdem A. Neurocognitive functioning during symptomatic states and remission in bipolar disorder and schizophrenia: A comparative study. Psychiatry Res. 2020 Oct; 292:113292 Epub 2020 July 15
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  42. Rurup L, Mathes B, Schmiedt-Fehr C, Wienke AS, Ozerdem A, Brand A, Basar-Eroglu C. Altered gamma and theta oscillations during multistable perception in schizophrenia. Int J Psychophysiol. 2020 Sep; 155:127-139 Epub 2020 June 09
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  43. Ho AM, Cabello-Arreola A, Markota M, Heppelmann CJ, Charlesworth MC, Ozerdem A, Mahajan G, Rajkowska G, Stockmeier CA, Frye MA, Choi DS, Veldic M. Label-free proteomics differences in the dorsolateral prefrontal cortex between bipolar disorder patients with and without psychosis. J Affect Disord. 2020 Jun 1; 270:165-173 Epub 2020 Apr 08
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  44. Ceylan D, Yilmaz S, Tuna G, Kant M, Er A, Ildiz A, Verim B, Akis M, Akan P, Islekel H, Veldic M, Frye M, Ozerdem A. Alterations in levels of 8-Oxo-2'-deoxyguanosine and 8-Oxoguanine DNA glycosylase 1 during a current episode and after remission in unipolar and bipolar depression. Psychoneuroendocrinology. 2020 Apr; 114:104600 Epub 2020 Feb 07
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  45. Cabello-Arreola A, Ho AM, Ozerdem A, Cuellar-Barboza AB, Kucuker MU, Heppelmann CJ, Charlesworth MC, Ceylan D, Stockmeier CA, Rajkowska G, Frye MA, Choi DS, Veldic M. Differential Dorsolateral Prefrontal Cortex Proteomic Profiles of Suicide Victims with Mood Disorders. Genes (Basel). 2020 Feb 27; 11 (3)
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  46. Ceylan D, Tufekci KU, Keskinoglu P, Genc S, Ozerdem A. Circulating exosomal microRNAs in bipolar disorder. J Affect Disord. 2020 Feb 1; 262:99-107 Epub 2019 Nov 01
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  47. Yildiz A, Alkin T, Özerdem A, Sagduyu K, Demopulos CM. Neuroleptic malignant sydrome: a case that may shed new light into the etiology and treatment. Aust N Z J Psychiatry. 2003; 37(4):493-494.
  48. Can G, Bora E, Ildiz A, Ulas G, Ongun CH, Sprooten E, Frangou S, Inal NE, Ozerdem A. Neurocognition in young offspring of individuals with bipolar disorder: The role of co-existing familial and clinical high-risk for bipolar disorder. Psychiatry Res. 2019 Nov; 281:112565 Epub 2019 Sept 22
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  49. de Zwarte SMC, Brouwer RM, Agartz I, Alda M, Aleman A, Alpert KI, Bearden CE, Bertolino A, Bois C, Bonvino A, Bramon E, Buimer EEL, Cahn W, Cannon DM, Cannon TD, Caseras X, Castro-Fornieles J, Chen Q, Chung Y, De la Serna E, Di Giorgio A, Doucet GE, Eker MC, Erk S, Fears SC, Foley SF, Frangou S, Frankland A, Fullerton JM, Glahn DC, Goghari VM, Goldman AL, Gonul AS, Gruber O, de Haan L, Hajek T, Hawkins EL, Heinz A, Hillegers MHJ, Hulshoff Pol HE, Hultman CM, Ingvar M, Johansson V, Jonsson EG, Kane F, Kempton MJ, Koenis MMG, Kopecek M, Krabbendam L, Kramer B, Lawrie SM, Lenroot RK, Marcelis M, Marsman JC, Mattay VS, McDonald C, Meyer-Lindenberg A, Michielse S, Mitchell PB, Moreno D, Murray RM, Mwangi B, Najt P, Neilson E, Newport J, van Os J, Overs B, Ozerdem A, Picchioni MM, Richter A, Roberts G, Aydogan AS, Schofield PR, Simsek F, Soares JC, Sugranyes G, Toulopoulou T, Tronchin G, Walter H, Wang L, Weinberger DR, Whalley HC, Yalin N, Andreassen OA, Ching CRK, van Erp TGM, Turner JA, Jahanshad N, Thompson PM, Kahn RS, van Haren NEM. The Association Between Familial Risk and Brain Abnormalities Is Disease Specific: An ENIGMA-Relatives Study of Schizophrenia and Bipolar Disorder. Biol Psychiatry. 2019 Oct 1; 86 (7):545-556 Epub 2019 June 13
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  50. Bora E, Can G, Ildiz A, Ulas G, Ongun CH, Inal NE, Ozerdem A. Neurocognitive heterogeneity in young offspring of patients with bipolar disorder: The effect of putative clinical stages. J Affect Disord. 2019 Oct 1; 257:130-135 Epub 2019 July 05
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  51. Bora E, McIntyre RS, Özerdem A. Neurocognitive and neuroimaging correlates of obesity and components of metabolic syndrome in bipolar disorder: a systematic review. Psychol Med. 2019 Apr; 49(5):738-749.
  52. Yalin N, Saricicek A, Hidiroglu C, Zugman A, Direk N, Ada E, Cavusoglu B, Er A, Isik G, Ceylan D, Tunca Z, Kempton MJ, Özerdem A. Cortical thickness and surface area as an endophenotype in bipolar disorder type I patients and their first-degree relatives. Neuroimage Clin. 2019 Jan 29.
  53. Ceylan D, Akan P, Doyuran K, Can G, Ersen A, Misir E, Özerdem A. Increased serum levels of NMDA receptor antibodies in female patients with bipolar disorder. Turkish J Clinical Psychiatry. 2019; 22.
  54. Bora E, Akgül Ö, Ceylan D, Özerdem A. Neurological soft signs in bipolar disorder in comparison to healthy controls and schizophrenia: A meta-analysis. Eur Neuropsychopharmacol. 2018 Nov; 28(11):1185-1193.
  55. Ceylan D, Scola G, Tunca Z, Isaacs-Trepanier C, Can G, Andreazza AC, Young LT, Özerdem A. DNA redox modulations and global DNA methylation in bipolar disorder: Effects of sex, smoking and illness state. Psychiatry Res. 2018 Mar; 261:589-596.
  56. Onat M, Inal Emiroglu N, Baykara B, Özerdem A, Özyurt G, Öztürk Y, Sahin Ü, Ildiz A, Kaptancik Bilgiç B, Hidiroglu Ongun C, Pekcanlar Akay A. Executive functions and impulsivity in suicide attempter adolescents with major depressive disorder Psychiatry and Clinical Pscyhopharmacology. 2018.
  57. Ceylan D, Tuna G, Kirkali G, Tunca Z, Can G, Arat HE, Kant M, Dizdaroglu M, Özerdem A. Oxidatively-induced DNA damage and base excision repair in euthymic patients with bipolar disorder. DNA Repair (Amst). 2018; 65:64-72.
  58. Özerdem A, Ceylan D, Targitay B. The relationship between Lithium and cancer proliferation: A case-based review of the literature. Curr Drug Metab. 2018; 19(8):653-662.
  59. Bora E, Özerdem A. Meta-analysis of longitudinal studies of cognition in bipolar disorder: comparison with healthy controls and schizophrenia. Psychol Med. 2017 Dec; 47(16):2753-2766.
  60. Ince SÇ, Günüsen NP, Özerdem A, Özisik S. Diabetes Self-Care Views of Individuals With Severe Mental Illness and Comorbid Type 2 Diabetes and of Those Only With Type 2 Diabetes. Arch Psychiatr Nurs. 2017 Aug; 31(4):386-393.
  61. Bora E, Özerdem A. A meta-analysis of neurocognition in youth with familial high risk for bipolar disorder. Eur Psychiatry. 2017 Jul; 44:17-23. Epub 2021 Jul 01.
  62. Bora E, Özerdem A. Social cognition in first-degree relatives of patients with bipolar disorder: A meta-analysis. Eur Neuropsychopharmacol. 2017 Apr; 27(4):293-300.
  63. Safari R, Tunca Z, Özerdem A, Ceylan D, Yalçin Y, Sakizli M. Glial cell-derived neurotrophic factor gene polymorpisms affect severity and functionality of bipolar disorder. J Integr Neurosci. 2017; 16(4):471-481.
  64. Bora E, Hidiroglu C, Özerdem A, Kaçar ÖF, Sarisoy G, Civil Arslan F, Aydemir Ö, Cubukcuoglu Tas Z, Vahip S, Atalay A, Atasoy N, Atesci F, Tümkaya S. Executive dysfunction and cognitive subgroups in a large sample of euthymic patients with bipolar disorder. Eur Neuropsychopharmacol. 2016 Aug; 26(8):1338-1347.
  65. Safari R, Salimi R, Tunca Z, Ceylan D, Sakizli M. Mutation/SNP analysis in EF-hand calcium binding domain of mitochondrial Ca[Formula: see text] uptake 1 gene in bipolar disorder patients. J Integr Neurosci. 2016 Jun; 15 (2):163-73 Epub 2016 June 13
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  66. Basar E, Schmiedt-Fehr C, Mathes B, Femir B, Emek-Savas DD, Tülay E, Tan D, Düzgün A, Güntekin B, Özerdem A, Yener G, Basar-Eroglu C. What does the broken brain say to the neuroscientist? Oscillations and connectivity in schizophrenia, Alzheimer's disease, and bipolar disorder. Int J Psychophysiol. 2016 May; 103:135-148.
  67. Sariçiçek A, Zorlu N, Yalin N, Hidiroglu C, Çavusoglu B, Ceylan D, Ada E, Tunca Z, Özerdem A. Abnormal white matter integrity as a structural endophenotype for bipolar disorder. Psychol Med. 2016 May; 46:1547-1558.
  68. Tan D, Özerdem A, Güntekin B, Atagün MI, Tülay E, Karadag F, Basar E. Increased Beta Frequency (15-30 Hz) Oscillatory Responses in Euthymic Bipolar Patients Under Lithium Monotherapy. Clin EEG Neurosci. 2016 Apr; 47(2):87-95.
  69. Özerdem A, Ceylan D, Can G. Neurobiology of Risk for Bipolar Disorder. Curr Treat Options Psychiatry. 2016; 3(4):315-329.
  70. Sagir B, Binbay T, Ceylan D, Yalin N, Özerdem A, Alptekin K. Cavum Vergae and Schizophrenia: Brain Imaging Findings and Treatment Outcome of a Case with 25 Years of Untreated Psychosis. Turk Psikiyatri Derg. 2015 Winter; 26(4):295-298.
  71. Hidiroglu C, Torres IJ, Er A, Isik G, Yalin N, Yatham LN, Ceylan D, Özerdem A. Response inhibition and interference control in patients with bipolar I disorder and first-degree relatives. Bipolar Disord. 2015 Nov; 17(7):781-794. Epub 2012 Nov 01.
  72. Sariçiçek A, Yalin N, Hidiroglu C, Çavusoglu B, Tas C, Ceylan D, Zorlu N, Ada E, Tunca Z, Özerdem A. Neuroanatomical correlates of genetic risk for bipolar disorder: A voxel- based morphometry study in bipolar type I patients and healthy first degree relatives. J Affect Disord. 2015 Nov; 1(186):110-118.
  73. Tunca Z, Bayin M, Alkn T, Özerdem A, Resmi H, Akan P. A Preliminary Observation of Increased Glial Cell Line-Derived Neurotrophic Factor in Manic Switch due to electrocon- vulsive Treatment in Depressive Patients. J ECT. 2015 Sep; 31(3):167-172.
  74. Alural B, Özerdem A, Allmer J, Genc K, Genc S. Lithium protects against paraquat neu- rotoxicity by NRF2 activation and miR-34a inhibition in SH-SY5Y cells. Front Cell Neurosci. 2015 May; 28(9):209.
  75. Özyurt G, Öztura I, Alkin T, Özerdem A. Anxiety disorder due to epilepsy: a case report. Turk Psikiyatri Derg. 2015 Spring; 26(1):71-75.
  76. Prieto ML, Youngstrom EA, Ozerdem A, Altinbas K, Quiroz D, Aydemir O, Yalin N, Geske JR, Feeder SE, Angst J, Frye MA. Different patterns of manic/hypomanic symptoms in depression: A pilot modification of the hypomania checklist-32 to assess mixed depression. J Affect Disord. 2015 Feb 1; 172:355-60 Epub 2014 Oct 13
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  77. Tunca Z, Kivircik Akdede B, Özerdem A, Alkin T, Polat S, Ceylan D, Bayin M, Cengizçetin Kocuk N, Simsek S, Resmi H, Akan P. Diverse glial cell line-derived neurotrophic factor (GDNF) support between mania and schizophrenia: A comparative study in four major psychiatric disorders. Eur Psychiatry. 2015 Feb; 30(2):198-204.
  78. Özerdem A. Revisiting allostatis and allostatic load in bipolar disorder (invited article). Düsünen Adam The Journal of Psychiatry and Neurological Sciences. 2015; 28(3):183-188.
  79. Safari R, Tunca Z, Özerdem A, Ceylan D, Yazicioglu CE, Sakizli M. New alterations at potentially regulated regions of the Glial Derived Neurotrophic Factor gene in bipolar disorder. J Affect Disord. 2014 Oct; 164:244-250.
  80. Tunca Z, Özerdem A, Ceylan D, Yalçin Y, Can G, Resmi H, Akan P, Ergör G, Aydemir O, Cengisiz C, Kerim D. Alterations in BDNF (brain derived neurotrophic factor) and GDNF (glial cell line-derived neurotrophic factor) serum levels in bipolar disorder: The role of lithium. J Affect Disord. 2014 Sep; 166:196-200.
  81. Özerdem A, Rasgon N. Women with bipolar disorder: a lifetime challenge from diagnosis to treatment. Bipolar Disord. 2014; 16(1):1-4.
  82. Özerdem A, Tunca Z, Çimrin D, Hidiroglu C, Ergör G. Female vulnerability for thyroid function abnormality in bipolar disorder: role of lithium treatment. Bipolar Disord.. 2014 Feb; 16(1):72-82.
  83. Özerdem A. The Shark of Psychiatry (invited article). Archives of Neuropsychiatry. 2014; 51:187-188.
  84. Altinbas K, Ozerdem A, Prieto ML, Fuentes ME, Yalin N, Ersoy Z, Aydemir O, Quiroz D, Oztekin S, Geske JR, Feeder SE, Angst J, Frye MA. A multinational study to pilot the modified Hypomania Checklist (mHCL) in the assessment of mixed depression. J Affect Disord. 2014 Jan; 152-154:478-82 Epub 2013 Aug 23
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  86. Atagün MI, Güntekin B, Ozerdem A, Tülay E, Basar E. Decrease of theta response in euthymic bipolar patients during an oddball paradigm. Cogn Neurodyn. 2013 Jun; 7(3):213-223. Epub 2017 Jun 01.
  87. Hidiroglu C, Demirci Ö, Tunca Z, Gürz NS, Lombardo L, Glahn DC, Özerdem A. Can risk-taking be an endophenotype for bipolar disorder? A study on patients with bipolar disorder type I and their first-degree relatives. J Int Neuropsychol Soc. 2013 Apr; 19(4):474-482.
  88. Özerdem A, Güntekin B, Atagün MI, Basar E. Brain oscillations in bipolar disorder in search of new biomarkers. Application of Brain Oscillations in Neuropsychiatric Diseases (Supplements to Clinical Neurophysiology. 2013; 62:207-221.
  89. Basar E, Basar-Eroglu C, Özerdem A, Rossini PM, Yener GG. Application of brain os- cillations to neuropsychiatric diseases: a new land? Preface. Suppl Clin Neurophysiol. 2013; 62.
  90. Basar E, Guntekin B, Atagun I, Turp B, Tulay E, Özerdem A. Brain’s alpha activity is highly reduced in euthymic bipolar disorder patients. Cogn. Neurodyn. 2012; 6(1):11-20.
  91. Frye MA, Ha K, Kanba S, Kato T, McElroy SL, Ozerdem A, Vazquez G, Vieta E. International consensus group on depression prevention in bipolar disorder. J Clin Psychiatry 2011 Oct; 72 (10):1295-310
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  92. Özerdem A, Güntekin B, Atagün I, Turp B, Basar E. Reduced long distance gamma (28- 48 Hz) coherence in euthymic patients with bipolar disorder. J Affect Disord. 2011 Aug; 132(3):325-332.
  93. Dumlu K, Orhon Z, Özerdem A, Tural U, Ulas H, Tunca Z. Treatment-induced manic switch in the course of unipolar depression can predict bipolarity: cluster analysis based evidence. J Affect Disord. 2011; 134(1-3):91-101.
  94. Özerdem A, Güntekin B, Saatçi E, Tunca Z, Basar E. Disturbance in long distance gamma coherence in bipolar disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2010 Aug 16; 34(6):861-865.
  95. Cakir S, Özerdem A. Iki Uçlu Bozuklukta Psikoterapötik ve Psikososyal Sagaltimlar: Sistematik Bir Gözden Geçirme. Turk Psikiyatri Derg. 2010; 21(2):143-154.
  96. Yatham LN, Torres IJ, Malhi GS, Frangou S, Glahn DC, Bearden CE, Burdick KE, Martínez-Arán A, Dittmann S, Goldberg JF, Özerdem A, Aydemir O, Chengappa KN. The International Society for Bipolar Disorders-Battery for Assessment of Neurocognition (ISBD- BANC). Bipolar Disord. 2010 Jun ; 12(4):351-363.
  97. Serim B, Ulas H, Özerdem A, Alkin T. Electroconvulsive therapy in an adolescent pregnant patient. Prog Neuropsychopharmacol Biol Psychiatry. 2010 Apr 16; 34(3):546-547.
  98. Özerdem A, Oguz M, Miklowitz DJ, Cimilli C. Family focused treatment for patients with bipolar disorder in Turkey: a case series. Fam Process. Sept 2009; 48(3):417-428.
  99. Özerdem A, S Kocaaslan, Tunca Z, Basar E. Event related oscillations in euthymic patients with bipolar disorder. Neuroscience Letters. 2008 Oct 17; 444(1):5-10.
  100. Emiroglu N, Özerdem A, Miklowitz DJ, Baykara A, Akay A. Co-occurence of blepharospasm, tourettism and obsessive-compulsive symptoms during lamotrigine treatment. World Psychiatry. 2008; 7(2):110-112.
  101. Emiroglu N, Özerdem A, Miklowitz DJ, Baykara A, Akay A. Mood and disruptive behavior disorders and symptoms in the offspring of patients with bipolar I disorder. World Psychiatry. 2008; 7(2):110-112.
  102. Tunca Z, Resmi H, Ozkara HA, Ciliv G, Celtikci B, Alptekin K, Özerdem A, Akdede BK, Baykara B, Birsoy B, Ergor G. Increased hexosaminidase activity in antipsychotic-induced extrapyramidal side effects: Possible association with higher occurrence in bipolar disorder patients. Prog Neuropsychopharmacol Biol Psychiatry. 2008; 1(32):1214-1220.
  103. Özerdem A, Güntekin B, Tunca Z, Basar E. Brain oscillatory responses in patients with bipolar disorder manic episode before and after valproate treatment. Brain Res.. 2008; 1235:98-108.
  104. Alkin T, Onur E, Özerdem A. Co-occurence of blepharospasm, tourettism and obsessive-compulsive symptoms during lamotrigine treatment. Prog Neuropsychopharmacol Biol Psychiatry. 2007; 15;31(6):1339-1340.
  105. Akvardar Y, Akdede BB, Özerdem A, Eser E, Topkaya S, Alptekin K.. Assessment of quality of life with the WHOQOL-BREF in a group of Turkish psychiatric patients compared with diabetic and healthy subjects. Psychiatry Clin Neurosci. 2006; 60(6):693-699.
  106. Çelik L, Kaynak T, Özerdem A, Kocak N, Kaynak S. Disappointment of patients on antidepressant therapy after excimer laser treatment. J Cataract Refract Surg. 2006; 32(10):1775-1776.
  107. Arkar H, Sorias O, Tunca Z, Safak C, Alkin T, Akdede BB, Sahin S, Akvardar Y, Sari Ö, Özerdem A, Cimilli C. Factorial structure, validity and reliability of the Turkish temperament and character inventory. Turkish Journal of Psychiatry. 2005; 16(3):190-204.
  108. Kaya N, Resmi H, Özerdem A, Güner G, Tunca Z. Increased inositol monophosphates activity by lithium treatment in bipolar patients. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 2004; 28:521-527.
  109. Özerdem A, Schimidt ME, Manji HK, Risinger RC, Potter WZ. Chronic Lithium administration enhances noradrenergic responses to intravenous administration of the alpha-2 antagonist idazoxan in healthy volunteers. J of Clin Psychopharamacol. 2004; 24(2):150-154.
  110. Monkul S, Özerdem A. Structural magnetic resonance imaging (MRI) studies in bipolar disorder. Türkish Journal of Psychiatry. 2003; 14(3):225-232.
  111. Özerdem A, Fidaner H, Tunca Z, Coskun L, Erbay Dündar P. Telephone consultation of psychiatric cases at primary care: a pilot study. New Symposium. 2002; 40(2):57-59.
  112. Özerdem A, Tunca Z, Kaya N. The relatively good prognosis of bipolar disorders in a Turkish bipolar clinic. J Affect Disord. 2001; 64:27-34.
  113. Yildiz A, Özerdem A. Psychotic mania: clinical aspects and course (review). Türkish Journal of Psychiatry. 2000; 11(3):228-236.
  114. Tunca Z, Ergene Ü, Fidaner H, Cimilli C, Özerdem A, Alkin T, Ünal Aslan B. Reevalution of serum cortisol in conversion disorder with seizure (pseudoseizure). Psychosomatics. 2000; 41(2):152-153.
  115. Tunca Z, Fidaner H, Cimilli C, Kaya N, Biber B, Yesil S, Özerdem A. Is conversion disorder biologically related with depression? A DST study. Biological Psychiatry. 1996; 39(1):216-219.
  116. Özerdem A, Özkiziltan S, Alptekin K, Alkin T, Tunca Z. A life-time follow-up Schedule for bipolar affective disorder and its use in a case. Turkish Journal of Psychiatry. 1996; 7(2).
  117. Tunca Z, Fidaner H, Cimilli C, Kaya N, Biber B, Yesil S, Özerdem A. Dexamethasone suppression test in conversion disorder. Turkish Journal of Psychiatry. 1995; 6(1):30-35.
  118. Alkin T, Özerdem A, Baklan B, Öztürk V. Diazepam induced amnesia: A case report. Clinical Psychopharmacology Bulletin. 1992; 2(3):58-60.
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