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Richard A. Oeckler, M.D., Ph.D.

  1. Critical Care Specialist
  2. Pulmonologist
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Publications

  1. Zhong Q, Chaudhary CW, Stellpflug CL, Wolf CS, Diedrich DA, Lehnertz A, Meyer TJ, Oeckler RA, De Moraes AG. High-Flow Nasal Cannula on the General Ward for Patients With COVID-19 Enhances ICU and Rapid Response Team Resource Allocation. Respir Care. 2022 Jul 19 Epub 2022 July 19
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  2. Koubek R, Brady A, Gopalratnam K, Oeckler R, Kennedy CC, Kelm D. Virtual Procedural Supervision During the COVID-19 Pandemic: A Novel Pilot for Supervising Invasive Bedside Procedures in the ICU. Mayo Clin Proc Innov Qual Outcomes. 2021 Dec; 5 (6):992-996 Epub 2021 Sept 21
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  3. Sarge T, Baedorf-Kassis E, Banner-Goodspeed V, Novack V, Loring SH, Gong MN, Cook D, Talmor D, Beitler JR, EPVent-2 Study Group. Effect of Esophageal Pressure-guided Positive End-Expiratory Pressure on Survival from Acute Respiratory Distress Syndrome: A Risk-based and Mechanistic Reanalysis of the EPVent-2 Trial. Am J Respir Crit Care Med. 2021 Nov 15; 204 (10):1153-1163
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  4. Johnstone J, Meade M, Lauzier F, Marshall J, Duan E, Dionne J, Arabi YM, Heels-Ansdell D, Thabane L, Lamarche D, Surette M, Zytaruk N, Mehta S, Dodek P, McIntyre L, English S, Rochwerg B, Karachi T, Henderson W, Wood G, Ovakim D, Herridge M, Granton J, Wilcox ME, Goffi A, Stelfox HT, Niven D, Muscedere J, Lamontagne F, D'Aragon F, St-Arnaud C, Ball I, Nagpal D, Girard M, Aslanian P, Charbonney E, Williamson D, Sligl W, Friedrich J, Adhikari NK, Marquis F, Archambault P, Khwaja K, Kristof A, Kutsogiannis J, Zarychanski R, Paunovic B, Reeve B, Lellouche F, Hosek P, Tsang J, Binnie A, Trop S, Loubani O, Hall R, Cirone R, Reynolds S, Lysecki P, Golan E, Cartin-Ceba R, Taylor R, Cook D, Prevention of Severe Pneumonia and Endotracheal Colonization Trial (PROSPECT) Investigators and the Canadian Critical Care Trials Group. Effect of Probiotics on Incident Ventilator-Associated Pneumonia in Critically Ill Patients: A Randomized Clinical Trial. JAMA. 2021 Sep 21; 326 (11):1024-1033
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  5. Zhou Y, Holets SR, Li M, Cortes-Puentes GA, Meyer TJ, Hanson AC, Schulte PJ, Oeckler RA. Etiology, incidence, and outcomes of patient-ventilator asynchrony in critically-ill patients undergoing invasive mechanical ventilation. Sci Rep. 2021 Jun 11; 11 (1):12390 Epub 2021 June 11
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  6. Zhou Y, Holets SR, Li M, Meyer TJ, Rangel Latuche LJ, Oeckler RA, Bohman JK. The Impact of a Standardized Refractory Hypoxemia Protocol on Outcome of Subjects Receiving Venovenous Extracorporeal Membrane Oxygenation. Respir Care. 2021 May; 66 (5):837-844 Epub 2021 Mar 02
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  7. O'Horo JC, Cerhan JR, Cahn EJ, Bauer PR, Temesgen Z, Ebbert J, Abril A, Abu Saleh OM, Assi M, Berbari EF, Bierle DM, Bosch W, Burger CD, Cano Cevallos EJ, Clements CM, Carmona Porquera EM, Castillo Almeida NE, Challener DW, Chesdachai S, Comba IY, Corsini Campioli CG, Crane SJ, Dababneh AS, Enzler MJ, Fadel HJ, Ganesh R, De Moraes AG, Go JR, Gordon JE, Gurram PR, Guru PK, Halverson EL, Harrison MF, Heaton HA, Hurt R, Kasten MJ, Lee AS, Levy ER, Libertin CR, Mallea JM, Marshall WF 3rd, Matcha G, Meehan AM, Franco PM, Morice WG 2nd, O'Brien JJ, Oeckler R, Ommen S, Oravec CP, Orenstein R, Ough NJ, Palraj R, Patel BM, Pureza VS, Pickering B, Phelan DM, Razonable RR, Rizza S, Sampathkumar P, Sanghavi DK, Sen A, Siegel JL, Singbartl K, Shah AS, Shweta F, Speicher LL, Suh G, Tabaja H Jr, Tande A, Ting HH, Tontz RC 3rd, Vaillant JJ, Vergidis P, Warsame MY, Yetmar ZA, Zomok CCD, Williams AW, Badley AD. Outcomes of COVID-19 With the Mayo Clinic Model of Care and Research. Mayo Clin Proc. 2021 Mar; 96 (3):601-618 Epub 2020 Dec 26
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  8. Bai C, Chotirmall SH, Rello J, Alba GA, Ginns LC, Krishnan JA, Rogers R, Bendstrup E, Burgel PR, Chalmers JD, Chua A, Crothers KA, Duggal A, Kim YW, Laffey JG, Luna CM, Niederman MS, Raghu G, Ramirez JA, Riera J, Roca O, Tamae-Kakazu M, Torres A, Watkins RR, Barrecheguren M, Belliato M, Chami HA, Chen R, Cortes-Puentes GA, Delacruz C, Hayes MM, Heunks LMA, Holets SR, Hough CL, Jagpal S, Jeon K, Johkoh T, Lee MM, Liebler J, McElvaney GN, Moskowitz A, Oeckler RA, Ojanguren I, O'Regan A, Pletz MW, Rhee CK, Schultz MJ, Storti E, Strange C, Thomson CC, Torriani FJ, Wang X, Wuyts W, Xu T, Yang D, Zhang Z, Wilson KC. Updated guidance on the management of COVID-19: from an American Thoracic Society/European Respiratory Society coordinated International Task Force (29 July 2020). Eur Respir Rev. 2020 Sep 30; 29 (157) Epub 2020 Oct 05
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  9. Clements CM, Oeckler RA, Heaton HA, Diedrich DA, Brown DR, Sampathkumar P. Creating Successful Emergency Department and Intensive Care Unit Team Dynamics. Mayo Clin Proc. 2020 Sep; 95 (9S):S35-S37 Epub 2020 July 30
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  10. Gallo de Moraes A, Holets SR, Tescher AN, Elmer J, Arteaga GM, Schears G, Patch RK, Bohman JK, Oeckler RA. The Clinical Effect of an Early, Protocolized Approach to Mechanical Ventilation for Severe and Refractory Hypoxemia. Respir Care. 2020 Apr; 65 (4):413-419 Epub 2020 Jan 28
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  11. Smischney NJ, Nicholson WT, Brown DR, Gallo De Moraes A, Hoskote SS, Pickering B, Oeckler RA, Iyer VN, Gajic O, Schroeder DR, Bauer PR. Ketamine/propofol admixture vs etomidate for intubation in the critically ill: KEEP PACE Randomized clinical trial. J Trauma Acute Care Surg. 2019 Oct; 87 (4):883-891
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  12. Cortes-Puentes GA, Westerly B, Schiavo D, Wang S, Stroetz R, Walters B, Hubmayr RD, Oeckler RA. Hypercapnia Alters Alveolar Epithelial Repair by a pH-Dependent and Adenylate Cyclase-Mediated Mechanism. Sci Rep. 2019 Jan 23; 9 (1):349
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  13. Gallo De Moraes A, Oeckler RA. Should PEEP be titrated based on esophageal pressures? Chest Physician. 2019; 14(10):55-61. Epub 1900 Jan 01.
  14. Cortes-Puentes GA, Oeckler RA, Marini JJ. Physiology-guided management of hemodynamics in acute respiratory distress syndrome. Ann Transl Med. 2018 Sep; 6 (18):353
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  15. Cortes-Puentes GA, Gard KE, Adams AB, Dries DJ, Quintel M, Oeckler RA, Gattinoni L, Marini JJ. Positional effects on the distributions of ventilation and end-expiratory gas volume in the asymmetric chest-a quantitative lung computed tomographic analysis. Intensive Care Med Exp. 2018 Apr 10; 6 (1):9
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  16. Gallo de Moraes A, O'Horo JC, Sevilla-Berrios RA, Iacovella G, Lenhertz A, Schmidt J, Elmer J, Oeckler R, Caples S, Jensen JB. Expanding the Presence of Primary Services at Rapid Response Team Activations: A Quality Improvement Project. Qual Manag Health Care. 2018 Jan/Mar; 27 (1):50-55
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  17. Wang F, Knutson K, Alcaino C, Linden DR, Gibbons SJ, Kashyap P, Grover M, Oeckler R, Gottlieb PA, Li HJ, Leiter AB, Farrugia G, Beyder A. Mechanosensitive ion channel Piezo2 is important for enterochromaffin cell response to mechanical forces. J Physiol. 2017 Jan 1; 595 (1):79-91 Epub 2016 Aug 13
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  18. Alhurani RE, Oeckler RA, Franco PM, Jenkins SM, Gajic O, Pannu SR. Refractory Hypoxemia and Use of Rescue Strategies. A U.S. National Survey of Adult Intensivists. Ann Am Thorac Soc. 2016 Jul; 13 (7):1105-14
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  19. Nagre N, Wang S, Kellett T, Kanagasabai R, Deng J, Nishi M, Shilo K, Oeckler RA, Yalowich JC, Takeshima H, Christman J, Hubmayr RD, Zhao X. TRIM72 modulates caveolar endocytosis in repair of lung cells. Am J Physiol Lung Cell Mol Physiol. 2016 Mar 1; 310 (5):L452-64 Epub 2015 Dec 04
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  20. Ice CJ, Personett HA, Frazee EN, Dierkhising RA, Kashyap R, Oeckler RA. Risk Factors for Dexmedetomidine-Associated Hemodynamic Instability in Noncardiac Intensive Care Unit Patients. Anesth Analg. 2016 Feb; 122: (2)462-9.
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  21. Ramar K, De Moraes AG, Selim B, Holets S, Oeckler R. Effectiveness of hands-on tutoring and guided self-directed learning versus self-directed learning alone to educate critical care fellows on mechanical ventilation - a pilot project. Med Educ Online. 2016; 21:32727 Epub 2016 Sept 29
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  22. Hubmayr RD, Oeckler RA. The hidden consequences of ventilator management decisions. Respir Care. 2014 Aug; 59(8):1302-5.
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  23. Kotsenas AL, Campeau NG, Oeckler RA, Kuzo RS. Evaluation of suspected aspirated beverage can pull tab: radiographs may not be enough. Case Rep Radiol. 2014; 2014:196960 Epub 2014 Dec 14
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  24. Oeckler RA, Hubmayr RD. Alveolar cell wounding by deforming stress in the lung. Current Respiratory Medicine Reviews. 2012; 8(2):108-15.
  25. Qian Q, Thanarajasingam U, Oeckler RA, Sawyer MD, Sethi S, Edwards WD. Expanded spectrum of antineutrophil cytoplasmic antibody-negative vasculitis involving vessels from capillaries to medium-sized arteries. Arthritis Care Res (Hoboken). 2011 Nov; 63(11):1634-8.
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  26. Mattingley JS, Holets SR, Oeckler RA, Stroetz RW, Buck CF, Hubmayr RD. Sizing the lung of mechanically ventilated patients. Crit Care. 2011; 15 (1):R60 Epub 2011 Feb 14
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  27. Oeckler RA, Lee WY, Park MG, Kofler O, Rasmussen DL, Lee HB, Belete H, Walters BJ, Stroetz RW, Hubmayr RD. Determinants of plasma membrane wounding by deforming stress. Am J Physiol Lung Cell Mol Physiol. 2010 Dec; 299 (6):L826-33 Epub 2010 Oct 01
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  28. Oeckler RA, Hubmayr RD. Cell wounding and repair in ventilator injured lungs. Respir Physiol Neurobiol. 2008 Nov 30; 163 (1-3):44-53 Epub 2008 June 28
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  29. Oeckler RA, Hubmayr RD. Alveolar Microstrain and the Dark Side of the Lung. Crit Care. 2008; 11(6):177.
  30. Oeckler RA, Hubmayr RD. Ventilator-associated lung injury: a search for better therapeutic targets. Eur Respir J. 2007 Dec; 30(6):1216-26.
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  31. Mingone CJ, Gupte SA, Ali N, Oeckler RA, Wolin MS. Thiol oxidation inhibits nitric oxide-mediated pulmonary artery relaxation and guanylate cyclase stimulation. Am J Physiol Lung Cell Mol Physiol. 2006 Mar; 290(3):L549-57. Epub 2005 Nov 04.
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  32. Oeckler RA, Arcuino E, Ahmad M, Olson SC, Wolin MS. Cytosolic NADH redox and thiol oxidation regulate pulmonary arterial force through ERK MAP kinase. Am J Physiol Lung Cell Mol Physiol. 2005 Jun; 288(6):L1017-25. Epub 2005 Jan 21
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  33. Olson S, Oeckler R, Li X, Du L, Traganos F, Zhao X, Burke-Wolin T. Angiotensin II stimulates nitric oxide production in pulmonary artery endothelium via the type 2 receptor. Am J Physiol Lung Cell Mol Physiol. 2004 Sep; 287(3):L559-68. Epub 2004 May 21
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  34. Oeckler RA, Kaminski PM, Wolin MS. Stretch enhances contraction of bovine coronary arteries via an NAD(P)H oxidase-mediated activation of the extracellular signal-regulated kinase mitogen-activated protein kinase cascade. Circ Res. 2003 Jan 10; 92(1):23-31.
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  35. Wolin MS, Oeckler RA, Iesaki T, Gupte SA. Oxidant and Redox Signaling Mechanisms in Vascular Responses to Oxygen, Stretch and NO. Japanese Circulation Society. 2003; 67(1):145.
  36. Wolin MS, Gupte SA, Oeckler RA. Superoxide in the vascular system. J Vasc Res. 2002 May-Jun; 39(3):191-207.
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  37. Oeckler RA, Wolin MS. Stretch-enhanced contractile function requires NADH oxidase activation and oxidant-mediated signaling through src and EGFR receptor. AHA 2002 State of the Art; Featured Research Session. Circulation. 2002; 106(19):861.
  38. Oeckler RA, Wolin MS. New concepts in vascular nitric oxide signaling. Curr Atheroscler Rep. 2000 Sep; 2(5):437-44.
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  39. Paul MD, Oeckler RA, Falkenstein R. One year follow-up of no-stitch cataract wound healing using vitamin supplementation J of Cataract Refract Surg. 1994; 4:48-50.
PST-20226519