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Jack C. O'Horo, M.D., M.P.H.

  1. Critical Care Specialist
  2. Infectious Disease Specialist
  3. Internist
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Publications

  1. Comba IY, O'Horo JC, Gordon JE, Falck-Ytter Y, Moore MM, Morgan RL, Mustafa RA, Bhimraj A. Beyond Words: Enhancing Clinical Guideline Comprehension With Icons. Open Forum Infect Dis. 2024 Nov; 11 (11):ofae637 Epub 2024 Oct 23
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  2. Yu KC, O'Horo JC, Ai C, Jung M, Bastow S. Clinical characteristics associated with hospital-onset bacteremia and fungemia among cancer and transplant patients. Infect Control Hosp Epidemiol. 2024 Oct 23; 1-8 [Epub ahead of print]
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  3. O'Horo JC, Challener DW, Kudrna C, Buckmeier JR, Peters SG, Kor DJ, Matson MW, Badley AD, Burger CD, Chaudhry R. Leveraging real-time patient data during the COVID-19 pandemic. Infect Control Hosp Epidemiol. 2024 Oct 8; 1-2 Epub 2024 Oct 08
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  4. O'Horo JC. Holding Our Breath-Looking for Treatments for Mild to Moderate COVID-19. JAMA Netw Open. 2024 Oct 1; 7 (10):e2439283 Epub 2024 Oct 01
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  5. Tekin A, Joghataee M, Rovati L, Truong H, Castillo-Zambrano C, Kushagra K, Nikravangolsefid N, Ozkan M, Gupta A, Herasevich V, Domecq J, O'Horo J, Gajic O. Development and validation of a preliminary multivariable diagnostic model for identifying unusual infections in hospitalized patients. Biomol Biomed. 2024 Sep 6; 24 (5):1387-1399 Epub 2024 Sept 06
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  6. Ghosh P, Niesen MJM, Pawlowski C, Bandi H, Yoo U, Lenehan PJ, Kumar-M P, Nadig M, Ross J, Ardhanari S, O'Horo JC, Venkatakrishnan AJ, Rosen CJ, Telenti A, Hurt RT, Soundararajan V. Case-control study on post-COVID-19 conditions reveals severe acute infection and chronic pulmonary disease as potential risk factors. iScience. 2024 Aug 16; 27 (8):110406 Epub 2024 June 28
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  7. Bhimraj A, Morgan RL, Shumaker AH, Baden LR, Cheng VC, Edwards KM, Gallagher JC, Gandhi RT, Muller WJ, Nakamura MM, O'Horo JC, Shafer RW, Shoham S, Murad MH, Mustafa RA, Sultan S, Falck-Ytter Y. Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients With COVID-19 (September 2022). Clin Infect Dis. 2024 Jun 27; 78 (7):e250-e349
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  8. Comba IY, Go JR, Vaillant J, O'Horo JC, Stevens RW, Palraj R, Abu Saleh O. Sequential Time to Positivity as a Prognostic Indicator in Staphylococcus aureus Bacteremia. Open Forum Infect Dis. 2024 Apr; 11 (4):ofae173 Epub 2024 Mar 21
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  9. Howick JF 5th, Saric P, Elwazir M, Newman DB, Pellikka PA, Howick AS, O'Horo JC, Cooper LT Jr, Deshmukh AJ, Ganesh R, Hurt R, Gersh B, Bois JP. A Pragmatic Study of Cardiovascular Disease During Long-Term COVID-19. Am J Med. 2024 Mar 26. [Epub ahead of print]
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  10. Hernandez SE, Solomon D, Moon J, Parmasad V, Wiegmann D, Bennett NT, Ferren RS, Fitzsimmons AJ, Lepak AJ, O'Horo JC, Pop-Vicas AE, Schulz LT, Safdar N. Understanding clinical implementation coordinators' experiences in deploying evidence-based interventions. Am J Health Syst Pharm. 2024 Feb 8; 81 (4):120-128
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  11. Bhimraj A, Morgan RL, Shumaker AH, Lavergne V, Baden L, Cheng VCC, Edwards KM, Gandhi R, Muller WJ, O'Horo JC, Shoham S, Murad MH, Mustafa RA, Sultan S, Falck-Ytter Y. Infectious Diseases Society of America guidelines on the treatment and management of patients with Covid-19 (April 2020). Clinical Infectious Diseases. 2024; 78 (7):e83-e102
  12. Bell CF, Gibbons DC, Drysdale M, Birch HJ, Lloyd EJ, Patel V, Carpenter C, Carlson K, Calay ES, Puranik A, Wagner TE, O'Horo JC, Razonable RR. Real-world effectiveness of sotrovimab in preventing hospitalization and mortality in high-risk patients with COVID-19 in the United States: A cohort study from the Mayo Clinic electronic health records. PLoS One. 2024; 19 (7):e0304822 Epub 2024 July 16
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  13. Scotch M, Lauer K, Wieben ED, Cherukuri Y, Cunningham JM, Klee EW, Harrington JJ, Lau JS, McDonough SJ, Mutawe M, O'Horo JC, Rentmeester CE, Schlicher NR, White VT, Schneider SK, Vedell PT, Wang X, Yao JD, Pritt BS, Norgan AP. Genomic epidemiology reveals the dominance of Hennepin County in the transmission of SARS-CoV-2 in Minnesota from 2020 to 2022. mSphere. 2023 Dec 20; 8 (6):e0023223 Epub 2023 Oct 26
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  14. Kasten MJ, Lahr BD, Parisapogu A, Yetmar ZA, O'Horo JC, Orenstein R, Moreno Franco P, Razonable RR, Vergidis P, Shah AS, Enzler MJ, Inwards DJ, Bauer PR. COVID-19 outcome is not affected by anti-CD20 or high-titer convalescent plasma in immunosuppressed patients. Sci Rep. 2023 Dec 1; 13 (1):21249 Epub 2023 Dec 01
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  15. Ambrose N, Amin A, Anderson B, Bertagnolli M, Campion F, Chow D, Danan R, D'Arinzo L, Drews A, Erlandson K, Fitzgerald K, Gaspar F, Gong C, Hanna G, Hawley H, Jones S, Lopansri B, Mullen T, Musser J, O'Horo J, Piantadosi S, Pritt B, Razonable R, Rele S, Roberts S, Sandmeyer S, Stein D, Te J, Vahidy F, Webb B, Welch N, Wood A, Yttri J. The Influence of Social Determinants on Receiving Outpatient Treatment with Monoclonal Antibodies, Disease Risk, and Effectiveness for COVID-19. J Gen Intern Med. 2023 Dec; 38 (16):3472-3481 Epub 2023 Sept 15
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  16. Haddad SF, Lahr BD, Patarroyo SS, Chesdachai S, Kies KD, O'Horo JC, DeSimone DC, Sendi P, Baddour LM. Bloodstream Infection Due to Coagulase-Negative Staphylococci: Impact of Species on Prevalence of Infective Endocarditis. Antibiotics (Basel). 2023 Sep 18; 12 (9) Epub 2023 Sept 18
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  17. Tekin A, Truong HH, Rovati L, Lal A, Gerberi DJ, Gajic O, O'Horo JC. The Diagnostic Accuracy of Metagenomic Next-Generation Sequencing in Diagnosing Pneumocystis Pneumonia: A Systemic Review and Meta-analysis. Open Forum Infect Dis. 2023 Sep; 10(9):ofad442. Epub 2023 Aug 18.
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  18. Mendoza MA, Ranganath N, Garcia BB, Stevens RW, Lahr B, O'Horo J, Stulak J, Shah A. Left Ventricular Assist Device: Review of Antimicrobial Prophylaxis Strategies and Incidence of Infections at a Tertiary Care Center 12-Year Experience. Open Forum Infect Dis. 2023 Sep; 10 (9):ofad465 Epub 2023 Sept 08
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  19. Challener DW, Gao X, Tehranian S, Kashani KB, O'Horo JC. Body temperature and infection in critically ill patients on continuous kidney replacement therapy. BMC Nephrol. 2023 Jun 7; 24 (1):161 Epub 2023 June 07
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  20. Maredia H, Sartori-Valinotti JC, Ranganath N, Tosh PK, O'Horo JC, Shah AS. Supportive Care Management Recommendations for Mucocutaneous Manifestations of Monkeypox Infection. Mayo Clin Proc. 2023 Jun; 98 (6):828-832 Epub 2023 Apr 29
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  21. Smith BB, Bosch W, O'Horo JC, Girardo ME, Bolton PB, Murray AW, Hirte IL, Singbartl K, Martin DP. Surgical site infections during the COVID-19 era: A retrospective, multicenter analysis. Am J Infect Control. 2023 Jun; 51 (6):607-611 Epub 2022 Sept 23
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  22. Ambrose N, Amin A, Anderson B, Barrera-Oro J, Bertagnolli M, Campion F, Chow D, Danan R, D'Arinzo L, Drews A, Erlandson K, Fitzgerald K, Garcia M, Gaspar FW, Gong C, Hanna G, Jones S, Lopansri B, Musser J, O'Horo J, Piantadosi S, Pritt B, Razonable RR, Roberts S, Sandmeyer S, Stein D, Vahidy F, Webb B, Yttri J. Neutralizing Monoclonal Antibody Use and COVID-19 Infection Outcomes. JAMA Netw Open. 2023 Apr 3; 6 (4):e239694 Epub 2023 Apr 03
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  23. Matson RP, Niesen MJM, Levy ER, Opp DN, Lenehan PJ, Donadio G, O'Horo JC, Venkatakrishnan AJ, Badley AD, Soundararajan V. Paediatric safety assessment of BNT162b2 vaccination in a multistate hospital-based electronic health record system in the USA: a retrospective analysis. Lancet Digit Health. 2023 Apr; 5 (4):e206-e216
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  24. Lal A, Rayes H, O'Horo JC, Singh TD, Gajic O, Kashyap R. Septic shock definitions and associated outcomes in blood culture positive critically ill patients. Ann Transl Med. 2023 Mar 15; 11 (5):192 Epub 2023 Feb 24
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  25. Dyrbye LN, Gordon J, O'Horo J, Belford SM, Wright M, Satele DV, West CP. Relationships Between EHR-Based Audit Log Data and Physician Burnout and Clinical Practice Process Measures. Mayo Clin Proc. 2023 Mar; 98 (3):398-409
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  26. Ranganath N, O'Horo JC, Challener DW, Tulledge-Scheitel SM, Pike ML, O'Brien M, Razonable RR, Shah A. Rebound Phenomenon After Nirmatrelvir/Ritonavir Treatment of Coronavirus Disease 2019 (COVID-19) in High-Risk Persons. Clin Infect Dis. 2023 Feb 8; 76 (3):e537-e539
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  27. Tekin A, Pinevich Y, Herasevich V, Pickering BW, Vergidis P, Gajic O, O'Horo JC. Diagnostic delay in pulmonary blastomycosis: a case series reflecting a referral center experience. Infection. 2023 Feb; 51 (1):193-201 Epub 2022 July 01
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  28. Urtecho M, Torres Roldan VD, Nayfeh T, Espinoza Suarez NR, Ranganath N, Sampathkumar P, Chopra V, Safdar N, Prokop LJ, O'Horo JC. Comparing Complication Rates of Midline Catheter vs Peripherally Inserted Central Catheter. A Systematic Review and Meta-analysis. Open Forum Infect Dis. 2023 Feb; 10 (2):ofad024 Epub 2023 Jan 18
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  29. Venkatakrishnan AJ, Anand P, Lenehan PJ, Ghosh P, Suratekar R, Silvert E, Pawlowski C, Siroha A, Chowdhury DR, O'Horo JC, Yao JD, Pritt BS, Norgan AP, Hurt RT, Badley AD, Halamka J, Soundararajan V. Expanding repertoire of SARS-CoV-2 deletion mutations contributes to evolution of highly transmissible variants. Sci Rep. 2023 Jan 5; 13 (1):257 Epub 2023 Jan 05
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  30. Challener D, O'Horo J, Tande AJ. Infectious disease physician characteristics and prescription of meropenem in the hospital. Antimicrob Steward Healthc Epidemiol. 2023; 3 (1):e126 Epub 2023 July 17
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  31. Razonable RR, O'Horo JC, Hanson SN, Arndt RF, Speicher LL, Seville TA, Hall ST, Pike ML, Heyliger A, Larsen JJ, Ganesh R, Tulledge-Scheitel SM. Comparable Outcomes for Bebtelovimab and Ritonavir-Boosted Nirmatrelvir Treatment in High-Risk Patients With Coronavirus Disease-2019 During Severe Acute Respiratory Syndrome Coronavirus 2 BA.2 Omicron Epoch. J Infect Dis. 2022 Nov 11; 226 (10):1683-1687
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  32. Esquer Garrigos Z, Wingler MJB, Svoronos PA, Vijayvargiya P, Goodman-Meza D, O'Horo JC, Navalkele BD, Cretella D, Frame IJ, Parham J, Lucar J. Increased rates of blood culture contamination during the coronavirus disease 2019 pandemic. Infect Control Hosp Epidemiol. 2022 Nov; 43 (11):1719-1721 Epub 2021 June 24
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  33. Yetmar ZA, O'Horo JC, Seville MT, Speicher LL, Ganesh R, Razonable RR. Outcomes of Solid Organ Transplant Recipients Treated With Antispike Monoclonal Antibodies for Coronavirus Disease 2019 Across Variant Epochs: Impact of Comorbidities and Vaccination. Transplantation 2022 Nov 1; 106 (11):e507-e509 Epub 2022 Aug 15
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  34. Pritt BS, Mathison BA, Bradbury RS, Liewluck T, Nicolau S, O'Horo JC, Grunst D, Pinto MV, Swanson AA, Virk A. Imported Haycocknema perplexum Infection, United States(1). Emerg Infect Dis. 2022 Nov; 28 (11):2281-2284
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  35. Vergidis P, Levy ER, Ristagno EH, Iyer VN, O'Horo JC, Joshi AY. COVID-19 in patients with B cell immune deficiency. J Immunol Methods. 2022 Nov; 510:113351 Epub 2022 Sept 07
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  36. Challener D, Frank R, Kashani K, O'Horo J. Body temperature trends of critically Ill patients on continuous renal replacement therapy: A single-center retrospective study. Am J Med Sci. 2022 Oct; 364 (4):404-408 Epub 2022 Apr 20
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  37. Razonable RR, Tulledge-Scheitel SM, Hanson SN, Arndt RF, Speicher LL, Seville TA, Larsen JJ, Ganesh R, O'Horo JC. Real-world Clinical Outcomes of Bebtelovimab and Sotrovimab Treatment of High-risk Persons With Coronavirus Disease 2019 During the Omicron Epoch. Open Forum Infect Dis. 2022 Oct; 9 (10):ofac411 Epub 2022 Oct 06
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  38. Corsini Campioli C, O'Horo JC, Lahr BD, Wilson WR, DeSimone DC, Baddour LM, Van Gompel JJ, Sohail MR. Predictors of Treatment Failure in Patients With Pyogenic Brain Abscess. World Neurosurg X. 2022 Oct; 16:100134 Epub 2022 Aug 08
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  39. Byeon SK, Madugundu AK, Garapati K, Ramarajan MG, Saraswat M, Kumar-M P, Hughes T, Shah R, Patnaik MM, Chia N, Ashrafzadeh-Kian S, Yao JD, Pritt BS, Cattaneo R, Salama ME, Zenka RM, Kipp BR, Grebe SKG, Singh RJ, Sadighi Akha AA, Algeciras-Schimnich A, Dasari S, Olson JE, Walsh JR, Venkatakrishnan AJ, Jenkinson G, O'Horo JC, Badley AD, Pandey A. Development of a multiomics model for identification of predictive biomarkers for COVID-19 severity: a retrospective cohort study. Lancet Digit Health. 2022 Sep; 4 (9):e632-e645 Epub 2022 July 11
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  40. Razonable RR, O'Horo JC, Challener DW, Arndt L, Arndt RF, Clune CG, Culbertson TL, Hall ST, Heyliger A, Jackson TA, Kennedy BD, Larsen J, Hanson SN, Sweeten PW, Tulledge-Scheitel SM, Ganesh R. Curbing the Delta Surge: Clinical Outcomes After Treatment With Bamlanivimab-Etesevimab, Casirivimab-Imdevimab, or Sotrovimab for Mild to Moderate Coronavirus Disease 2019. Mayo Clin Proc. 2022 Sep; 97 (9):1641-1648 Epub 2022 June 23
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  41. Ranganath N, Tosh PK, O'Horo J, Sampathkumar P, Binnicker MJ, Shah AS. Monkeypox 2022: Gearing Up for Another Potential Public Health Crisis. Mayo Clin Proc. 2022 Sep; 97 (9):1694-1699 Epub 2022 Aug 16
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  42. Gordon JE, Belford SM, Aranguren DL, Blair D, Fleming R, Gajarawala NM, Heiderscheit J, Laabs SB, Looft KA, Rosedahl JK, O'Horo JC. Outcomes of Mayo Clinic reBoot camps for postimplementation training in the electronic health record. J Am Med Inform Assoc. 2022 Aug 16; 29 (9):1518-1524
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  43. Comba IY, Riestra Guiance I, Corsini Campioli C, Challener D, Sampathkumar P, Orenstein R, Gordon J, Bosch W, O'Horo JC. Clinical Characteristics and Outcomes of Patients With SARS-CoV-2 Reinfection. Mayo Clin Proc Innov Qual Outcomes. 2022 Aug; 6 (4):361-372 Epub 2022 May 30
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  44. Wight E, Swift M, O'Horo JC, Hainy C, Molella R, Morrow A, Breeher L. COVID-19 Infections in Health Care Personnel by Source of Exposure and Correlation With Community Incidence. J Occup Environ Med. 2022 Aug 1; 64 (8):675-678 Epub 2022 June 09
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  45. Yetmar ZA, Beam E, O'Horo JC, Seville MT, Brumble L, Ganesh R, Razonable RR. Outcomes of bebtelovimab and sotrovimab treatment of solid organ transplant recipients with mild-to-moderate coronavirus disease 2019 during the Omicron epoch. Transpl Infect Dis. 2022 Aug; 24 (4):e13901 Epub 2022 July 25
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  46. Yetmar ZA, Khodadadi RB, Seville MT, Brumble L, O'Horo JC, Ganesh R, Razonable RR. Outcomes of B-Cell-Depleted Patients With Coronavirus Disease 2019 Treated With Antispike Monoclonal Antibodies. Open Forum Infect Dis. 2022 Jul; 9 (7):ofac204 Epub 2022 Apr 14
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  47. Puranik A, Lenehan PJ, O'Horo JC, Pawlowski C, Niesen MJM, Virk A, Swift MD, Kremers W, Venkatakrishnan AJ, Gordon JE, Geyer HL, Speicher LL, Soundararajan V, Badley AD. Durability analysis of the highly effective BNT162b2 vaccine against COVID-19. PNAS Nexus. 2022 Jul; 1 (3):pgac082 Epub 2022 June 08
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  48. Pawlowski C, Silvert E, O'Horo JC, Lenehan PJ, Challener D, Gnass E, Murugadoss K, Ross J, Speicher L, Geyer H, Venkatakrishnan AJ, Badley AD, Soundararajan V. SARS-CoV-2 and influenza coinfection throughout the COVID-19 pandemic: an assessment of coinfection rates, cohort characteristics, and clinical outcomes. PNAS Nexus. 2022 Jul; 1 (3):pgac071 Epub 2022 July 04
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  49. Shah A, O'Horo JC. In patients with COVID-19 receiving IMV or ECMO, adding baricitinib to usual care reduced all-cause mortality. Ann Intern Med 2022 Jun; 175 (6):JC64 Epub 2022 June 07
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  50. Bhimraj A, Morgan RL, Shumaker AH, Baden L, Cheng VC, Edwards KM, Gandhi RT, Gallagher JC, Muller WJ, O'Horo JC, Shoham S, Wollins DS, Falck-Ytter Y. Lessons Learned from Coronavirus Disease 2019 (COVID-19) Therapies: Critical Perspectives From the Infectious Diseases Society of America (IDSA) COVID-19 Treatment Guideline Panel. Clin Infect Dis. 2022 May 3; 74 (9):1691-1695
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  51. Bhimraj A, Morgan RL, Shumaker AH, Lavergne V, Baden L, Cheng VC, Edwards KM, Gandhi RT, Gallagher JC, Muller WJ, O'Horo JC, Shoham S, Wollins DS, Falck-Ytter Y. Therapeutic Emergency Use Authorizations (EUAs) During Pandemics: Double-edged Swords. Clin Infect Dis. 2022 May 3; 74 (9):1686-1690
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  52. Ritchie CA, Johnson MM, Stowell JT, Idrees H, Toskich B, Paz-Fumagalli R, Montazeri S, Fortich S, Franco-Mesa C, Gloviczki P, Bjarnason H, Rivera C, Shaikh M, Moreno-Franco P, Sanghavi D, Marquez CP, McBane RD, Park MS, O'Horo JC, Meschia JF, Erben Y. Resolution of acute pulmonary embolism using anticoagulation therapy alone in coronavirus disease 2019. J Vasc Surg Venous Lymphat Disord. 2022 May; 10 (3):578-584.e2 Epub 2022 Jan 25
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  53. O'Horo J, Challener DW, Anderson RJ, Arndt RF, Ausman SE, Hall ST, Heyliger A, Kennedy BD, Sweeten PW, Ganesh R, Razonable RR. Rates of Severe Outcomes After Bamlanivimab-Etesevimab and Casirivimab-Imdevimab Treatment of High-Risk Patients With Mild to Moderate Coronavirus Disease 2019. Mayo Clin Proc. 2022 May; 97 (5):943-950 Epub 2022 Feb 23
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  54. Puranik A, Lenehan PJ, O'Horo JC, Pawlowski C, Virk A, Swift MD, Kremers W, Venkatakrishnan AJ, Challener DW, Breeher L, Gordon JE, Geyer HL, Speicher LL, Soundararajan V, Badley AD. Durability analysis of the highly effective mRNA-1273 vaccine against COVID-19. PNAS Nexus. 2022 May; 1 (2):pgac058 Epub 2022 May 20
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  55. Niesen MJM, Matson R, Puranik A, O'Horo JC, Pawlowski C, Vachon C, Challener D, Virk A, Swift M, Speicher L, Gordon J, Geyer H, Lenehan PJ, Venkatakrishnan AJ, Soundararajan V, Badley A. Third dose vaccination with mRNA-1273 or BNT162b2 vaccines improves protection against SARS-CoV-2 infection. PNAS Nexus. 2022 May; 1 (2):pgac042 Epub 2022 Apr 28
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  56. Niesen MJM, Pawlowski C, O'Horo JC, Challener DW, Silvert E, Donadio G, Lenehan PJ, Virk A, Swift MD, Speicher LL, Gordon JE, Geyer HL, Halamka JD, Venkatakrishnan AJ, Soundararajan V, Badley AD. Surveillance of Safety of 3 Doses of COVID-19 mRNA Vaccination Using Electronic Health Records. JAMA Netw Open. 2022 Apr 1; 5 (4):e227038 Epub 2022 Apr 01
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  57. Tekin A, Qamar S, Singh R, Bansal V, Sharma M, LeMahieu AM, Hanson AC, Schulte PJ, Bogojevic M, Deo N, Zec S, Valencia Morales DJ, Belden KA, Heavner SF, Kaufman M, Cheruku S, Danesh VC, Banner-Goodspeed VM, St Hill CA, Christie AB, Khan SA, Retford L, Boman K, Kumar VK, O'Horo JC, Domecq JP, Walkey AJ, Gajic O, Kashyap R, Surani S, Society of Critical Care Medicine (SCCM) Discovery Viral Infection and Respiratory Illness Universal Study (VIRUS): COVID-19 Registry Investigator Group. Association of latitude and altitude with adverse outcomes in patients with COVID-19: The VIRUS registry. World J Crit Care Med. 2022 Mar 9; 11 (2):102-111 Epub 2022 Mar 09
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  58. Corsini Campioli C, Castillo Almeida NE, O'Horo JC, Wilson WR, Cano E, DeSimone DC, Baddour LM, Sohail MR. Diagnosis, management, and outcomes of brain abscess due to gram-negative versus gram-positive bacteria. Int J Infect Dis. 2022 Feb; 115:189-194 Epub 2021 Dec 12
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  59. O'Horo JC, Challener DW, Speicher L, Bosch W, Seville MT, Bierle DM, Ganesh R, Wilker CG, Arndt RF, Arndt LL, Tulledge-Scheitel SM, Hanson SN, Razonable RR. Effectiveness of Monoclonal Antibodies in Preventing Severe COVID-19 With Emergence of the Delta Variant. Mayo Clin Proc. 2022 Feb; 97 (2):327-332 Epub 2021 Dec 16
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  60. Puranik A, Lenehan PJ, Silvert E, Niesen MJM, Corchado-Garcia J, O'Horo JC, Virk A, Swift MD, Gordon JE, Speicher LL, Geyer HL, Kremers W, Halamka J, Badley AD, Venkatakrishnan AJ, Soundararajan V. Comparative effectiveness of mRNA-1273 and BNT162b2 against symptomatic SARS-CoV-2 infection. Med. 2022 Jan 14; 3 (1):28-41.e8 Epub 2021 Dec 11
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  61. Nyman MA, Jose T, Croghan IT, Parkulo MA, Burger CD, Schroeder DR, Hurt RT, O'Horo JC. Utilization of an Electronic Health Record Integrated Risk Score to Predict Hospitalization Among COVID-19 Patients. J Prim Care Community Health. 2022 Jan-Dec; 13:21501319211069748
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  62. Shah A, Stevens RW, O'Horo JC, Dierkhising RA, Estes LL, Berbari EF, Tande AJ. Evaluation of an initiative to improve prophylactic antimicrobial prescribing in patients on extracorporeal membrane oxygenation (ECMO) through the application of three antimicrobial-spectrum scores. Infect Control Hosp Epidemiol. 2022 Jan; 43 (1):96-98 Epub 2021 Feb 09
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  63. Frahm M , Hutchinson A , Eveslage M , Shoden C , Barthels E , Czaplewski L , Zeuli J , O'Horo J . An interprofessional approach to managing patient violence in the ambulatory care setting. AAACN Viewpoint. 2022; 44 (5):4-9
  64. Corsini Campioli C, Challener D, Comba IY, Shah A, Wilson WR, Sohail MR, Van Gompel JJ, O'Horo JC. Overview and risk factors for postcraniotomy surgical site infection: A four-year experience. Antimicrob Steward Healthc Epidemiol. 2022; 2 (1):e14 Epub 2022 Jan 31
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  65. Stevens RW, Jensen K, Kooda K, Mara K, O'Horo JC, Shah A. A retrospective antibiotic prescribing assessment and examination of potential antibiotic stewardship targets in patients with COVID-19. JAC Antimicrob Resist. 2021 Dec; 3 (4):dlab170 Epub 2021 Nov 05
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  66. Corchado-Garcia J, Zemmour D, Hughes T, Bandi H, Cristea-Platon T, Lenehan P, Pawlowski C, Bade S, O'Horo JC, Gores GJ, Williams AW, Badley AD, Halamka J, Virk A, Swift MD, Wagner T, Soundararajan V. Analysis of the Effectiveness of the Ad26.COV2.S Adenoviral Vector Vaccine for Preventing COVID-19. JAMA Netw Open. 2021 Nov 1; 4 (11):e2132540 Epub 2021 Nov 01
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  67. Erben Y, Franco-Mesa C, Gloviczki P, Stone W, Quinones-Hinojoas A, Quinones-Hinojosa A, Meltzer AJ, Lin M, Greenway MRF, Hamid O, Devcic Z, Toskich B, Ritchie C, Lamb CJ, De Martino RR, Siegel J, Farres H, Hakaim AG, Sanghavi DK, Li Y, Rivera C, Moreno-Franco P, O'Keefe NL, Gopal N, Marquez CP, Huang JF, Kalra M, Shields R, Prudencio M, Gendron T, McBane R, Park M, Hoyne JB, Petrucelli L, O'Horo JC, Meschia JF. Deep vein thrombosis and pulmonary embolism among hospitalized coronavirus disease 2019-positive patients predicted for higher mortality and prolonged intensive care unit and hospital stays in a multisite healthcare system. J Vasc Surg Venous Lymphat Disord. 2021 Nov; 9 (6):1361-1370.e1 Epub 2021 Apr 06
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  68. O'Dowd TR, Mc Hugh JW, Theel ES, Wengenack NL, O'Horo JC, Enzler MJ, Vergidis P. Diagnostic Methods and Risk Factors for Severe Disease and Mortality in Blastomycosis: A Retrospective Cohort Study. J Fungi (Basel). 2021 Oct 20; 7(11).
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  69. Pawlowski C, Rincon-Hekking J, Awasthi S, Pandey V, Lenehan P, Venkatakrishnan AJ, Bade S, O'Horo JC, Virk A, Swift MD, Williams AW, Gores GJ, Badley AD, Halamka J, Soundararajan V. Cerebral Venous Sinus Thrombosis is not Significantly Linked to COVID-19 Vaccines or Non-COVID Vaccines in a Large Multi-State Health System. J Stroke Cerebrovasc Dis. 2021 Oct; 30 (10):105923 Epub 2021 June 16
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  70. Razonable RR, Pawlowski C, O'Horo JC, Arndt LL, Arndt R, Bierle DM, Borgen MD, Hanson SN, Hedin MC, Lenehan P, Puranik A, Seville MT, Speicher LL, Tulledge-Scheitel SM, Venkatakrishnan AJ, Wilker CG, Badley AD, Ganesh R. Casirivimab-Imdevimab treatment is associated with reduced rates of hospitalization among high-risk patients with mild to moderate coronavirus disease-19. EClinicalMedicine. 2021 Oct; 40:101102 Epub 2021 Aug 30
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  71. Corsini Campioli C, Castillo Almeida NE, O'Horo JC, Esquer Garrigos Z, Wilson WR, Cano E, DeSimone DC, Baddour LM, Van Gompel JJ, Sohail MR. Bacterial Brain Abscess: An Outline for Diagnosis and Management. Am J Med. 2021 Oct; 134 (10):1210-1217.e2 Epub 2021 July 21
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  154. Singh TD, O'Horo JC, Gajic O, Sakusic A, Day CN, Mandrekar J, Kashyap R, Reddy DRS, Rabinstein AA. Risk factors and outcomes of critically ill patients with acute brain failure: A novel end point. J Crit Care. 2018 Feb; 43:42-47 Epub 2017 Aug 18
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  155. Sakusic A, O'Horo JC, Dziadzko M, Volha D, Ali R, Singh TD, Kashyap R, Farrell AM, Fryer JD, Petersen R, Gajic O, Rabinstein AA. Potentially Modifiable Risk Factors for Long-Term Cognitive Impairment After Critical Illness: A Systematic Review. Mayo Clin Proc. 2018 Jan; 93 (1):68-82
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  156. Gallo de Moraes A, O'Horo JC, Sevilla-Berrios RA, Iacovella G, Lenhertz A, Schmidt J, Elmer J, Oeckler R, Caples S, Jensen JB. Expanding the Presence of Primary Services at Rapid Response Team Activations: A Quality Improvement Project. Qual Manag Health Care. 2018 Jan/Mar; 27 (1):50-55
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  157. Shah A, O'Horo JC, Wilson JW, Granger D, Theel ES. An Unusual Cluster of Neuroinvasive Lyme Disease Cases Presenting With Bannwarth Syndrome in the Midwest United States. Open Forum Infect Dis. 2018 Jan; 5(1):ofx276. Epub 2017 Dec 23.
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  158. O'Horo JC, Harper EP, El Rafei A, Ali R, DeSimone DC, Sakusic A, Abu Saleh OM, Marcelin JR, Tan EM, Rao AK, Sobel J, Tosh PK. Efficacy of Antitoxin Therapy in Treating Patients With Foodborne Botulism: A Systematic Review and Meta-analysis of Cases, 1923-2016. Clin Infect Dis. 2017 Dec 27; 66 (suppl_1):S43-S56
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  159. O'Horo JC, Sampathkumar P. Infections in Neurocritical Care. Neurocrit Care. 2017 Dec; 27 (3):458-467
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  160. Kogan A, Pennington KM, Vallabhajosyula S, Dziadzko M, Bennett CE, Jensen JB, Gajic O, O'Horo JC. Reliability and Validity of the Checklist for Early Recognition and Treatment of Acute Illness and Injury as a Charting Tool in the Medical Intensive Care Unit. Indian J Crit Care Med. 2017 Nov; 21 (11):746-750
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  161. Olchanski N, Dziadzko MA, Tiong IC, Daniels CE, Peters SG, O'Horo JC, Gong MN. Can a Novel ICU Data Display Positively Affect Patient Outcomes and Save Lives? J Med Syst. 2017 Sep 18; 41 (11):171 Epub 2017 Sept 18
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  162. O'Horo JC, Osmon DR, Abu Saleh OM, Marcelin JR, Gharaibeh KA, Hamadah AM, Barwise AK, Kayhart BM, McDonald JS, McDonald RJ, Leung N. Coadministration of Liposomal Amphotericin B and Contrast Medium Does Not Increase Risk of Kidney Injury. Antimicrob Agents Chemother. 2017 Aug; 61 (8) Epub 2017 July 25
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  163. Hoskote SS, Racedo Africano CJ, Braun AB, O'Horo JC, Sevilla Berrios RA, Loftsgard TO, Bryant KM, Iyer VN, Smischney NJ. Improving the Quality of Handoffs in Patient Care Between Critical Care Providers in the Intensive Care Unit. Am J Med Qual. 2017 Jul/Aug; 32 (4):376-383 Epub 2016 June 20
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  164. Garcia-Arguello LY, O'Horo JC, Farrell A, Blakney R, Sohail MR, Evans CT, Safdar N. Infections in the spinal cord-injured population: a systematic review. Spinal Cord. 2017 Jun; 55 (6):526-534 Epub 2016 Dec 06
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  165. Iyer AS, O'Horo JC, Thompson R. Purpura from a Tick Bite. Am J Med. 2017 Apr; 130 (4):e131-e132 Epub 2016 Dec 21
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  166. Amra S, O'Horo JC, Singh TD, Wilson GA, Kashyap R, Petersen R, Roberts RO, Fryer JD, Rabinstein AA, Gajic O. Derivation and validation of the automated search algorithms to identify cognitive impairment and dementia in electronic health records. J Crit Care. 2017 Feb; 37:202-205 Epub 2016 Oct 08
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  167. Velagapudi V, O'Horo JC, Vellanki A, Baker SP, Pidikiti R, Stoff JS, Tighe DA. Computer-assisted image processing 12 lead ECG model to diagnose hyperkalemia. J Electrocardiol. 2017 Jan - Feb; 50 (1):131-138 Epub 2016 Sept 09
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  170. Guru PK, O Horo JC, Lehrke HD, Winters JL, Wilson JW. Exchange transfusion for babesiosis when, how, and how long? Indian J Crit Care Med. 2016 Nov; 20 (11):674-676
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  171. O'Horo JC, Farrell A, Sohail MR, Safdar N. Carbapenem-resistant Enterobacteriaceae and endoscopy: An evolving threat. Am J Infect Control. 2016 Sep 1; 44 (9):1032-6 Epub 2016 May 11
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  172. Reddy DR, Singh TD, Guru PK, Sakusic A, Gajic O, O'Horo JC, Rabinstein AA. Identification of acute brain failure using electronic medical records. J Crit Care. 2016 Aug; 34:12-6 Epub 2016 Mar 16
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  174. Birkenkamp K, O'Horo JC, Kashyap R, Kloesel B, Lahr BD, Daniels CE, Nichols FC 3rd, Baddour LM. Empyema management: A cohort study evaluating antimicrobial therapy. J Infect. 2016 May; 72 (5):537-43 Epub 2016 Mar 15
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  175. Thongprayoon C, Harrison AM, O'Horo JC, Berrios RA, Pickering BW, Herasevich V. The Effect of an Electronic Checklist on Critical Care Provider Workload, Errors, and Performance. J Intensive Care Med. 2016 Mar; 31 (3):205-12 Epub 2014 Nov 12
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  176. Erdogan A, Dong Y, Chen X, Schmickl C, Sevilla Berrios RA, Garcia Arguello LY, Kashyap R, Kilickaya O, Pickering B, Gajic O, O'Horo JC. Development and validation of clinical performance assessment in simulated medical emergencies: an observational study. BMC Emerg Med. 2016 Jan 15; 16:4
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  177. O'Horo JC, Cawcutt KA, De Moraes AG, Sampathkumar P, Schears GJ. The Evidence Base for Prophylactic Antibiotics in Patients Receiving Extracorporeal Membrane Oxygenation. ASAIO J. 2016 Jan-Feb; 62: (1)6-10.
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  178. Tedja R, Wentink J, O'Horo JC, Thompson R, Sampathkumar P. Catheter-Associated Urinary Tract Infections in Intensive Care Unit Patients. Infect Control Hosp Epidemiol. 2015 Nov; 36: (11)1330-4.
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  179. Blakney R, Gudnadottir U, Warrack S, O'Horo JC, Anderson M, Sethi A, Schmitz M, Wang J, Duster M, Ide E, Safdar N. The relationship between patient functional status and environmental contamination by Clostridium difficile: a pilot study. Infection. 2015 Aug; 43(4):483-7. Epub 2015 Apr 14.
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  180. Thompson G, O'Horo JC, Pickering BW, Herasevich V. Impact of the Electronic Medical Record on Mortality, Length of Stay, and Cost in the Hospital and ICU: A Systematic Review and Metaanalysis. Crit Care Med. 2015 Jun; 43 (6):1276-82
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  181. Reddy DR, O'Horo JC, Hoskote SS, Moua T. Judgment of futile care in the ICU. Crit Care Med 2015 May; 43 (5):e151
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  182. O'Horo JC, Rogus-Pulia N, Garcia-Arguello L, Robbins J, Safdar N. Bedside diagnosis of dysphagia: a systematic review. J Hosp Med. 2015 Apr; 10 (4):256-65 Epub 2015 Jan 12
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  183. O'Horo JC, Sevilla Berrios RA, Elmer JL, Velagapudi V, Caples SM, Kashyap R, Jensen JB. The role of the primary care team in the rapid response system. J Crit Care. 2015 Apr; 30 (2):353-7 Epub 2014 Oct 30
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  184. Lan H, Thongprayoon C, Ahmed A, Herasevich V, Sampathkumar P, Gajic O, O'Horo JC. Automating Quality Metrics in the Era of Electronic Medical Records: Digital Signatures for Ventilator Bundle Compliance. Biomed Res Int. 2015; 2015:396508 Epub 2015 June 08
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  185. Smischney NJ, Cawcutt KA, O'Horo JC, Sevilla Berrios RA, Whalen FX. Intensive care unit readmission prevention checklist: is it worth the effort? J Eval Clin Pract. 2014 Aug; 20(4):348-51. Epub 2014 Apr 29.
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  186. Sevilla Berrios RA, O'Horo JC, Velagapudi V, Pulido JN. Correlation of left ventricular systolic dysfunction determined by low ejection fraction and 30-day mortality in patients with severe sepsis and septic shock: a systematic review and meta-analysis. J Crit Care. 2014 Aug; 29 (4):495-9 Epub 2014 Mar 21
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  187. Safdar N, O'Horo JC, Ghufran A, Bearden A, Didier ME, Chateau D, Maki DG. Chlorhexidine-impregnated dressing for prevention of catheter-related bloodstream infection: a meta-analysis*. Crit Care Med. 2014 Jul; 42 (7):1703-13
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  189. O'Horo JC, Jindai K, Kunzer B, Safdar N. Treatment of recurrent Clostridium difficile infection: a systematic review. Infection. 2014 Feb; 42 (1):43-59 Epub 2013 July 10
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  190. Safdar N, O'Horo JC, Maki DG. Arterial catheter-related bloodstream infection: incidence, pathogenesis, risk factors and prevention. J Hosp Infect. 2013 Nov; 85(3):189-95. Epub 2013 Sep 23.
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  191. Chopra V, O'Horo JC, Rogers MA, Maki DG, Safdar N. The risk of bloodstream infection associated with peripherally inserted central catheters compared with central venous catheters in adults: a systematic review and meta-analysis. Infect Control Hosp Epidemiol. 2013 Sep; 34(9):908-18. Epub 2013 Jul 26.
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  192. Chlebicki MP, Safdar N, O'Horo JC, Maki DG. Preoperative chlorhexidine shower or bath for prevention of surgical site infection: a meta-analysis. Am J Infect Control. 2013 Feb; 41(2):167-73. Epub 2012 Jun 19.
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  193. Safdar N, O'Horo JC, Mak R, Medow J. Agreement between the clinical pulmonary infection score and NHSN criteria for surveillance of ventilator associated pneumonia International Journal of Infection Control. 2013; 9: (1)10817.
  194. Kashiouris M, O'Horo JC, Pickering BW, Herasevich V. Diagnostic performance of electronic syndromic surveillance systems in acute care: a systematic review. Appl Clin Inform. 2013; 4 (2):212-24 Epub 2013 May 08
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  195. O'Horo JC, Thompson D, Safdar N. Is the gram stain useful in the microbiologic diagnosis of VAP? A meta-analysis. Clin Infect Dis. 2012 Aug; 55(4):551-61. Epub 2012 Jun 07.
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  196. O'Horo JC, Jones A, Sternke M, Harper C, Safdar N. Molecular techniques for diagnosis of Clostridium difficile infection: systematic review and meta-analysis. Mayo Clin Proc. 2012 Jul; 87(7):643-51.
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  197. Brauer E, O'Horo JC. An acute, progressive encephalopathy. WMJ. 2012 Apr; 111(2):66-7.
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  198. O'Horo JC, Andreev M, Hassan W, Anwar A. Evaluating traditional prognostic measures in patients undergoing hypothermia after cardiac arrest. Ther Hypothermia Temp Manag. 2012 Mar; 2: (1)24-9.
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  199. O'Horo JC, Omballi M, Tran TK, Jordan JP, Baumgardner DJ, Gennis MA. Effect of audit and feedback on improving handovers: a nonrandomized comparative study. J Grad Med Educ. 2012 Mar; 4: (1)42-6.
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  200. O'Horo JC, Silva GL, Munoz-Price LS, Safdar N. The efficacy of daily bathing with chlorhexidine for reducing healthcare-associated bloodstream infections: a meta-analysis. Infect Control Hosp Epidemiol. 2012 Mar; 33(3):257-67. Epub 2012 Jan 25.
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  201. Wang D, O'Horo J. Antifibrotic effects of omega-3 fatty acids in the heart: one possible treatment for diastolic heart failure. Trends Cardiovasc Med. 2011 Apr; 21(3):90-5.
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  202. O'Horo JC, Silva GL, Safdar N. Anti-infective locks for treatment of central line-associated bloodstream infection: a systematic review and meta-analysis. Am J Nephrol. 2011; 34(5):415-22. Epub 2011 Sep 21.
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  203. O'Horo J, Safdar N. The role of immunoglobulin for the treatment of Clostridium difficile infection: a systematic review. Int J Infect Dis. 2009 Nov; 13(6):663-7. Epub 2009 Jan 30.
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