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Cadman L. Leggett, M.D.

  1. Gastroenterologist
  2. Internist
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Publications

  1. Iyer PG, Leggett CL, Smith MS, Wolfsen HC, Jukema JB, Kusters CHJ, Jong MR, Fockens KN, Boers T, van der Putten JA, Pouw RE, Duits LC, Weusten BLAM, Herrero LA, Houben MHMG, Nagengast WB, Westerhof J, Alkhalaf A, Mallant-Hent R, Scholten P, Ragunath K, Seewald S, Elbe P, Silva FB, Barret M, Ortiz Fernandez-Sordo J, Moral Villarejo G, Pech O, Beyna T, Montazeri NSM, der Sommen FV, de With PH, de Groof AJ, Bergman JJ, BONS-AI consortium. Computer-aided diagnosis improves characterization of Barrett's neoplasia by general endoscopists (with video). Gastrointest Endosc. 2024 Oct; 100 (4):616-625.e8 Epub 2024 Apr 16
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  2. Bhattarai S, Algarin Perneth S, Padilla Zambrano H, Leggett CL. Clinical approach to the diagnosis and management of small bowel bleeding. Minerva Med. 2024 Sep 26 Epub 2024 Sept 26
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  3. McRae AN, Ticho AL, Liu Y, Ricardo-Silgado ML, Mangena NN, Jassir FF, Gonzalez-Izundegui D, Calderon G, Rohakhtar FR, Simon V, Li Y, Leggett C, Hurtado D, LaRusso N, Acosta AJ. Regulator of G-protein signaling expression in human intestinal enteroendocrine cells and potential role in satiety hormone secretion in health and obesity. EBioMedicine. 2024 Sep; 107:105283 Epub 2024 Aug 13
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  4. Laun SE, Kann L, Braun J, Gilbert S, Lunz D, Pierre F, Kalra A, Ma K, Tsai HL, Wang H, Jit S, Cheng Y, Ahmed Y, Wang KK, Leggett CL, Cellini A, Ioffe OB, Zaidi AH, Omstead AN, Jobe B, Korman L, Cornish D, Zellenrath P, Spaander M, Kuipers E, Perpetua L, Greenwald BD, Maddala T, Meltzer SJ. Validation of an Epigenetic Prognostic Assay to Accurately Risk-Stratify Patients with Barrett's Esophagus. Am J Gastroenterol. 2024 Aug 14 [Epub ahead of print]
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  5. Iyer PG, Slettedahl SW, Mahoney DW, Giakoumopoulos M, Olson MC, Krockenberger M, Taylor WR, Foote P, Berger C, Leggett C, Wu TT, Antpack E, Falk GW, Ginsberg GG, Abrams JA, Lightdale CJ, Ramirez F, Kahn A, Wolfsen H, Konda V, Trindade AJ, Kisiel JB. Algorithm Training and Testing for a Nonendoscopic Barrett's Esophagus Detection Test in Prospective Multicenter Cohorts. Clin Gastroenterol Hepatol. 2024 Aug; 22 (8):1596-1604.e4 Epub 2024 Mar 19
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  6. Phillips HP, Kamboj A, Leggett CL. The Diagnosis and Management of Gastroesophageal Reflux Disease: A concise review Mayo Clinic Proceedings. 2024.
  7. Vantanasiri K, Joseph A, Sachdeva K, Goyal R, Garg N, Adoor D, Kamboj AK, Codipilly DC, Leggett C, Wang KK, Harmsen W, Hayat U, Chak A, Bhatt A, Iyer PG. Rates of Recurrent Intestinal Metaplasia and Dysplasia After Successful Endoscopic Therapy of Barrett's Neoplasia by Endoscopic Mucosal Resection vs Endoscopic Submucosal Dissection and Ablation: A Large North American Multicenter Cohort. Am J Gastroenterol. 2024 May 10 [Epub ahead of print]
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  8. Akiki K, Mahmoud T, Alqaisieh MH, Sayegh LN, Lescalleet KE, Abu Dayyeh BK, Wong Kee Song LM, Larson MV, Bruining DH, Coelho-Prabhu N, Buttar NS, Sedlack RE, Chandrasekhara V, Leggett CL, Law RJ, Rajan E, Gleeson FC, Alexander JA, Storm AC. A novel blood-sensing capsule for rapid detection of upper GI bleeding: a prospective clinical trial. Gastrointest Endosc. 2024 May; 99 (5):712-720 Epub 2023 Dec 06
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  9. Parasa S, Berzin T, Leggett C, Gross S, Repici A, Ahmad OF, Chiang A, Coelho-Prabhu N, Cohen J, Dekker E, Keswani RN, Kahn CE, Hassan C, Petrick N, Mountney P, Ng J, Riegler M, Mori Y, Saito Y, Thakkar S, Waxman I, Wallace MB, Sharma P, Prepared by: ASGE AI Task Force. Consensus statements on the current landscape of artificial intelligence applications in endoscopy, addressing roadblocks, and advancing artificial intelligence in gastroenterology. Gastrointest Endosc. 2024 Apr 17 [Epub ahead of print]
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  10. Kamboj AK, Goyal R, Vantanasiri K, Sachdeva K, Passe M, Lansing R, Garg N, Chandi PS, Ramirez FC, Kahn A, Fukami N, Wolfsen HC, Krishna M, Pai RK, Hagen C, Lee HE, Wang KK, Leggett CL, Iyer PG. Clinical Outcomes After Endoscopic Management of Low-Risk and High-Risk T1a Esophageal Adenocarcinoma: A Multicenter Study. Am J Gastroenterol. 2024 Apr 01; 119(4):662-670. Epub 2023 Oct 05.
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  11. Leggett CL, Parasa S, Repici A, Berzin TM, Gross SA, Sharma P, Prepared by: ASGE AI Task Force. Physician perceptions on the current and future impact of artificial intelligence to the field of gastroenterology. Gastrointest Endosc. 2024 Apr; 99 (4):483-489.e2 Epub 2024 Feb 26
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  12. Dhaliwal L, Kamboj AK, Williams JL, Chandar AK, Sachdeva K, Gibbons E, Lansing R, Passe M, Perez JA, Avenir KLR, Martin SA, Leggett CL, Chak A, Falk GW, Wani S, Shaheen NJ, Kisiel JB, Iyer PG. Prevalence and Predictors of Barrett's Esophagus After Negative Initial Endoscopy: Analysis From Two National Databases. Clin Gastroenterol Hepatol. 2024 Mar; 22 (3):523-531.e3 Epub 2023 Sept 15
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  13. Agarwal S, Bell MG, Dhaliwal L, Codipilly DC, Dierkhising RA, Lansing R, Gibbons EE, Leggett CL, Kisiel JB, Iyer PG. Correction: Population Based Time Trends in the Epidemiology and Mortality of Gastroesophageal Junction and Esophageal Adenocarcinoma. Dig Dis Sci. 2024 Mar; 69(3):1070.
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  14. Leggett CL. Artificial Intelligence in Esophageal Diseases. Gastroenterol Hepatol (N Y). 2024 Mar; 20 (3):179-182
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  15. Agarwal S, Bell MG, Dhaliwal L, Codipilly DC, Dierkhising RA, Lansing R, Gibbons EE, Leggett CL, Kisiel JB, Iyer PG. Population Based Time Trends in the Epidemiology and Mortality of Gastroesophageal Junction and Esophageal Adenocarcinoma. Dig Dis Sci. 2024 Jan; 69(1):246-253. Epub 2023 Nov 01.
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  16. Leggett CL. Endoscopic screening for oesophageal cancer: empowering artificial intelligence with a high-quality examination. Lancet Gastroenterol Hepatol. 2024 Jan; 9 (1):4-5 Epub 2023 Nov 10
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  17. Kahn A, Song K, Dhaliwal L, Thanawala S, Hagen CE, Agarwal S, McDonald NM, Gabre JT, Falk GW, Ginsberg GG, Wolfsen HC, Ramirez FC, Leggett CL, Wang KK, Iyer PG. Long-term outcomes following successful endoscopic treatment of T1 esophageal adenocarcinoma: a multicenter cohort study. Gastrointest Endosc. 2023 Nov; 98(5):713-721. Epub 2023 Jun 24.
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  18. Iyer PG, Sachdeva K, Leggett CL, Codipilly DC, Abbas H, Anderson K, Kisiel JB, Asfahan S, Awasthi S, Anand P, Kumar M P, Singh SP, Shukla S, Bade S, Mahto C, Singh N, Yadav S, Padhye C. Development of Electronic Health Record-Based Machine Learning Models to Predict Barrett's Esophagus and Esophageal Adenocarcinoma Risk. Clin Transl Gastroenterol. 2023 Oct 1; 14 (10):e00637 Epub 2023 Oct 01
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  19. Pietrowicz M, Kamboj AK, Ishikawa K, Orbelo D, Yarlagadda MK, Buller K, Leggett C. Exploring Automated Detection of Barrett's Esophagus Via Machine Modeling and Acoustic Analysis Forum Acusticum 2023. 2023.
  20. Pietrowicz M, Orbelo D, Kamboj A, Yarlagadda MK, Buller K, Charney S, Leggett C, Ishikawa K. Developing A Machine-Learning Model For Detecting Intelligibility Differences in Individuals with Voice Disorders: A Feasibility Study Forum Acusticum 2023. 2023.
  21. Kamboj AK, Soontrapa P, Dubey D, Liewluck T, Leggett CL. Achalasia and Inclusion Body Myositis. Am J Gastroenterol. 2023 Aug 1; 118 (8):1317 Epub 2023 Apr 13
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  22. Parasa S, Repici A, Berzin T, Leggett C, Gross SA, Sharma P. Framework and metrics for the clinical use and implementation of artificial intelligence algorithms into endoscopy practice: recommendations from the American Society for Gastrointestinal Endoscopy Artificial Intelligence Task Force. Gastrointest Endosc. 2023 May; 97 (5):815-824.e1 Epub 2023 Feb 08
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  23. Samaddar P, Nusrat T, Gaddam S, Leggett CL, Dey S, Mitra D, Roy S, Arunachalam SP. On the design of ultra-wide band antipodal vivaldi antenna for biomedical sensors. Proceedings of the 2023 Design of Medical Devices Conference, DMD 2023. 2023; v001t09a006
  24. Fetzer JR, Redij R, Agarwal J, Rajagopal A, Gopalakrishnan K, Cherukuri ASS, League J, Guerrero Vinsard D, Leggett CL, Nayantara CP, Arunachalam SP. Endoscopic image enhanced deep learning algorithm for inflammatory bowel disease (IBD) polyp detection: feasibility study. IEEE International Conference on Electro Information Technology. 2023; 2023-May:655-9
  25. Lee J, Modi VK, Redij R, Gadam S, Gopalakrishnan K, Rajagopal A, Leggett CL, Arunachalam SP. AI based gland detection in Barrett's esophagus using optical coherence tomography for capsule endoscopy device. Proceedings of the 2023 Design of Medical Devices Conference, DMD 2023. 2023; v001t09a004
  26. Faghani S, Codipilly DC, David Vogelsang Vogelsang, Moassefi M, Rouzrokh P, Khosravi B, Agarwal S, Dhaliwal L, Katzka DA, Hagen C, Lewis J, Leggett CL, Erickson BJ, Iyer PG. Development of a deep learning model for the histologic diagnosis of dysplasia in Barrett's esophagus. Gastrointest Endosc. 2022 Dec; 96 (6):918-925.e3 Epub 2022 June 17
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  27. Iyer PG, Codipilly DC, Chandar AK, Agarwal S, Wang KK, Leggett CL, Latuche LR, Schulte PJ. Prediction of Progression in Barrett's Esophagus Using a Tissue Systems Pathology Test: A Pooled Analysis of International Multicenter Studies. Clin Gastroenterol Hepatol. 2022 Dec; 20 (12):2772-2779.e8 Epub 2022 Feb 22
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  28. Kahn A, Crook J, Heckman MG, Wieczorek MA, Sami S, Snyder D, Agarwal S, Santiago J, Fernandez-Sordo JO, Tan WK, Lansing R, Wang KK, Ragunath K, DiPietro M, Wolfsen H, Ramirez F, Fleischer D, Leggett CL, Iyer PG. Optimized Surveillance Intervals Following Endoscopic Eradication of Dysplastic Barrett's Esophagus: An International Cohort Study. Clin Gastroenterol Hepatol. 2022 Dec; 20 (12):2763-2771.e3 Epub 2022 Mar 01
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  29. Tome J, Kamboj AK, Leggett CL. The utility of esophageal transit scintigraphy in the diagnosis of dysphagia lusoria. Gastrointest Endosc. 2022 Oct; 96 (4):685-686 Epub 2022 June 18
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  30. Colon AR, Kamboj AK, Hagen CE, Rattan P, Coelho-Prabhu N, Buttar NS, Bruining DH, Storm AC, Larson MV, Viggiano TR, Wong Kee Song LM, Wang KK, Iyer PG, Katzka DA, Leggett CL. Acute Esophageal Necrosis: A Retrospective Cohort Study Highlighting the Mayo Clinic Experience. Mayo Clin Proc. 2022 Oct; 97 (10):1849-1860 Epub 2022 June 30
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  31. Kahn A, McKinley MJ, Stewart M, Wang KK, Iyer PG, Leggett CL, Trindade AJ. Artificial intelligence-enhanced volumetric laser endomicroscopy improves dysplasia detection in Barrett's esophagus in a randomized cross-over study. Sci Rep. 2022 Sep 29; 12 (1):16314 Epub 2022 Sept 29
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  32. Dong J, Grant C, Vuong B, Nishioka N, Gao AH, Beatty M, Baldwin G, Baillargeon A, Bablouzian A, Grahmann P, Bhat N, Ryan E, Barrios A, Giddings S, Ford T, Beaulieu-Ouellet E, Hosseiny SH, Lerman I, Trasischker W, Reddy R, Singh K, Gora M, Hyun D, Queneherve L, Wallace M, Wolfsen H, Sharma P, Wang KK, Leggett CL, Poneros J, Abrams JA, Lightdale C, Leeds S, Rosenberg M, Tearney GJ. Feasibility and Safety of Tethered Capsule Endomicroscopy in Patients With Barrett's Esophagus in a Multi-Center Study. Clin Gastroenterol Hepatol. 2022 Apr; 20 (4):756-765.e3 Epub 2021 Feb 04
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  33. Trindade AJ, Zhang J, Hauschild J, Leggett CL, Iyer PG. Impact of Coronavirus Disease 2019 on the Diagnosis and Therapy for Barrett's Esophagus and Esophageal Cancer in the United States. Gastroenterology 2022 Mar; 162 (3):978-980.e6 Epub 2021 Nov 19
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  34. Agarwal S, Alshelleh M, Scott J, Dhaliwal L, Codipilly DC, Dierkhising R, Leggett CL, Wang KK, Otaki FA, Trindade AJ, Iyer PG. Comparative outcomes of radiofrequency ablation and cryoballoon ablation in dysplastic Barrett's esophagus: a propensity score-matched cohort study. Gastrointest Endosc. 2022 Mar; 95 (3):422-431.e2 Epub 2021 Oct 06
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  35. Tome J, Kamboj AK, Leggett CL. Dysphagia in Dermatomyositis Due to Esophageal Adenocarcinoma. Clin Gastroenterol Hepatol. 2022 Mar; 20 (3):A15 Epub 2021 Mar 09
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  36. Kamboj AK, Kane SV, Leggett CL. Crohn's Disease of the Esophagus. Clin Gastroenterol Hepatol. 2022 Feb; 20 (2):A15-A16 Epub 2020 Oct 17
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  37. Hanada Y, Leggett CL, Iyer PG, Linn B, Mangels-Dick T, Wang KK. Spray cryotherapy prevents need for palliative stenting in patients with esophageal cancer-associated dysphagia. Dis Esophagus. 2022 Jan 7; 35 (1)
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  38. Agarwal S, Wang Y, Iyer PG, Leggett CL. Incidental Colonic Ganglioneuroma on Surveillance Colonoscopy. ACG Case Rep J. 2022 Jan; 9 (1):e00727 Epub 2022 Jan 11
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  39. Havlichek DH 3rd, Kamboj AK, Leggett CL. A Practical Guide to the Evaluation of Small Bowel Bleeding. Mayo Clin Proc. 2022 Jan; 97 (1):146-153
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  40. Aziz M, Dasari CS, Rai T, Alsop B, Gupta N, Vennalaganti P, Chandrasekar VT, Able K, Kennedy K, Wallace MB, Wang KK, Wolfsen HC, Sharma P, Leggett CL. Diagnostic performance of volumetric laser endomicroscopy for Barrett's esophagus dysplasia amongst gastroenterology trainees. Transl Gastroenterol Hepatol. 2022; 7:3 Epub 2022 Jan 25
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  41. Bouma BE, de Boer JF, Huang D, Jang IK, Yonetsu T, Leggett CL, Leitgeb R, Sampson DD, Suter M, Vakoc B, Villiger M, Wojtkowski M. Optical coherence tomography. Nat Rev Methods Primers. 2022; 2 Epub 2022 Oct 13
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  42. Park HC, Kamboj AK, Leggett CL, Li D, Wang KK, Li X. Comparative Study of Conventional and Ultrahigh-resolution Optical Coherence Tomography Imaging in Esophageal Neoplasia. Tech Innov Gastrointest Endosc. 2022; 24 (3):312-313 Epub 2022 Jan 17
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  43. Bouma BE, de Boer JF, Huang D, Jang IK, Yonetsu T, Leggett CL, Leitgeb R, Sampson DD, Suter M, Vakoc BJ, Villiger M, Wojtkowski M. Optical coherence tomography. Nature Reviews Methods Primers. 2022; 2 (1):79
  44. Leggett CL, Katzka DA. As far as the AI can see. Endoscopy 2021 Sep; 53 (9):884-885 Epub 2021 Aug 26
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  45. Visrodia K, Sawas T, Zakko L, Genere JR, Leggett C, Lutzke L, Wang KK. Scissor-type knife improves the safety of endoscopic submucosal dissection (ESD) among endoscopists without experience in ESD: a randomized ex vivo study. Endosc Int Open. 2021 Aug; 9 (8):E1207-E1213 Epub 2021 July 16
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  46. Marya NB, Powers PD, Chari ST, Gleeson FC, Leggett CL, Abu Dayyeh BK, Chandrasekhara V, Iyer PG, Majumder S, Pearson RK, Petersen BT, Rajan E, Sawas T, Storm AC, Vege SS, Chen S, Long Z, Hough DM, Mara K, Levy MJ. Utilisation of artificial intelligence for the development of an EUS-convolutional neural network model trained to enhance the diagnosis of autoimmune pancreatitis. Gut. 2021 Jul; 70 (7):1335-1344 Epub 2020 Oct 07
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  47. Dhaliwal L, Codipilly DC, Gandhi P, Johnson ML, Lansing R, Wang KK, Leggett CL, Katzka DA, Iyer PG. Neoplasia Detection Rate in Barrett's Esophagus and Its Impact on Missed Dysplasia: Results from a Large Population-Based Database. Clin Gastroenterol Hepatol. 2021 May; 19 (5):922-929.e1 Epub 2020 July 21
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  48. Struyvenberg MR, de Groof AJ, Fonolla R, van der Sommen F, de With PHN, Schoon EJ, Weusten BLAM, Leggett CL, Kahn A, Trindade AJ, Ganguly EK, Konda VJA, Lightdale CJ, Pleskow DK, Sethi A, Smith MS, Wallace MB, Wolfsen HC, Tearney GJ, Meijer SL, Vieth M, Pouw RE, Curvers WL, Bergman JJ. Prospective development and validation of a volumetric laser endomicroscopy computer algorithm for detection of Barrett's neoplasia. Gastrointest Endosc. 2021 Apr; 93 (4):871-879 Epub 2020 July 29
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  49. Kahn A, Priyan H, Dierkhising RA, Johnson ML, Lansing RM, Maixner KA, Wolfsen HC, Wallace MB, Ramirez FC, Fleischer DE, Leggett CL, Wang KK, Iyer PG. Outcomes of radiofrequency ablation by manual versus self-sizing circumferential balloon catheters for the treatment of dysplastic Barrett's esophagus: a multicenter comparative cohort study. Gastrointest Endosc. 2021 Apr; 93 (4):880-887.e1 Epub 2020 July 31
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  50. Struyvenberg M, Kahn A, Fleischer D, Swager AF, Bouma B, Ganguly EK, Konda V, Lightdale CJ, Pleskow D, Sethi A, Smith M, Trindade AJ, Wallace MB, Wang K, Wolfsen HC, Tearney GJ, Curvers WL, Leggett CL, Bergman JJ. Expert assessment on volumetric laser endomicroscopy full scans in Barrett's esophagus patients with or without high grade dysplasia or early cancer. Endoscopy. 2021 Mar; 53 (3):218-225 Epub 2020 June 17
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  51. Raphael KL, Inamdar S, McKinley MJ, Martinez N, Cavaliere K, Kahn A, Leggett CL, Iyer P, Wang KK, Trindade AJ. Longitudinal and Circumferential Distributions of Dysplasia and Early Neoplasia in Barrett's Esophagus: A Pooled Analysis of Three Prospective Studies. Clin Transl Gastroenterol. 2021 Feb 22; 12 (2):e00311
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  52. Ji H, Chandrasekhara V, Leggett CL. Magnetic sphincter augmentation device malfunction. Gastrointest Endosc. 2021 Jan; 93 (1):261-262 Epub 2020 July 17
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  53. Kamboj AK, Kahn A, Leggett CL. Narrowed-spectrum technologies in endoscopic imaging of the upper gastrointestinal tract Techniques and Innovations in Gastrointestinal Endoscopy. 2021; 23 (1):19-29
  54. Codipilly DC, Sawas T, Dhaliwal L, Johnson ML, Lansing R, Wang KK, Leggett CL, Katzka DA, Iyer PG. Epidemiology and Outcomes of Young-Onset Esophageal Adenocarcinoma: An Analysis from a Population-Based Database. Cancer Epidemiol Biomarkers Prev. 2021 Jan; 30 (1):142-149 Epub 2020 Dec 11
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  55. Struyvenberg MR, de Groof AJ, Kahn A, Weusten BLAM, Fleischer DE, Ganguly EK, Konda VJA, Lightdale CJ, Pleskow DK, Sethi A, Smith MS, Trindade AJ, Wallace MB, Wolfsen HC, Tearney GJ, Meijer SL, Leggett CL, Bergman JJGHM, Curvers WL. Multicenter study on the diagnostic performance of multiframe volumetric laser endomicroscopy targets for Barrett's esophagus neoplasia with histopathology correlation. Dis Esophagus. 2020 Dec 7; 33 (12)
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  56. Otaki F, Ma GK, Krigel A, Dierkhising RA, Lewis JT, Blevins CH, Gopalakrishnan NP, Ravindran A, Johnson ML, Leggett CL, Wigle D, Wang KK, Falk GW, Abrams JA, Nakagawa H, Rustgi AK, Wang TC, Lightdale CJ, Ginsberg GG, Iyer PG. Outcomes of patients with submucosal (T1b) esophageal adenocarcinoma: a multicenter cohort study. Gastrointest Endosc. 2020 Jul; 92 (1):31-39.e1 Epub 2020 Jan 15
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  57. Rajan E, Martinez M, Gorospe E, Al Bawardy B, Dobashi A, Mara KC, Hansel SL, Bruining DH, Murray JA, Leggett CL, Nehra V, Iyer PG, Pasha SF, Leighton JA, Shiff AD, Gurudu SR, Raffals LE, Lavey C, Katzka DA, Chen CH. Prospective multicenter study to evaluate capsule endoscopy competency using a validated assessment tool. Gastrointest Endosc. 2020 May; 91 (5):1140-1145 Epub 2019 Dec 26
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  58. Kahn A, Kamboj AK, Trindade AJ, Buras MR, Golafshar MA, Iyer PG, Wang KK, Leggett CL. Validation and optimization of enhanced volumetric laser endomicroscopy scoring systems for Barrett's esophagus dysplasia Techniques and Innovations in Gastrointestinal Endoscopy. 2020; 22 (4):185-90
  59. Wang KK, Leggett C. Finding Barrett's oesophagus: is there a machine learning approach in our future? Lancet Digit Health 2020 Jan; 2 (1):e6-e7 Epub 2019 Dec 23
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  60. Kamboj AK, Hoversten P, Kahn AK, Trindade AJ, Iyer PG, Wang KK, Leggett CL. Interpretation of volumetric laser endomicroscopy in Barrett's esophagus using image enhancement software. Dis Esophagus. 2019 Dec 30; 32 (11)
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  61. Lu J, Roy B, Anderson M, Leggett CL, Levy MJ, Pogue B, Hasan T, Wang KK. Verteporfin- and sodium porfimer-mediated photodynamic therapy enhances pancreatic cancer cell death without activating stromal cells in the microenvironment. J Biomed Opt. 2019 Nov; 24 (11):1-11
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  62. Sami SS, Ravindran A, Kahn A, Snyder D, Santiago J, Ortiz-Fernandez-Sordo J, Tan WK, Dierkhising RA, Crook JE, Heckman MG, Johnson ML, Lansing R, Ragunath K, di Pietro M, Wolfsen H, Ramirez F, Fleischer D, Wang KK, Leggett CL, Katzka DA, Iyer PG. Timeline and location of recurrence following successful ablation in Barrett's oesophagus: an international multicentre study. Gut. 2019 Aug; 68 (8):1379-1385 Epub 2019 Jan 11
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  63. Trindade AJ, McKinley MJ, Fan C, Leggett CL, Kahn A, Pleskow DK. Endoscopic Surveillance of Barrett's Esophagus Using Volumetric Laser Endomicroscopy With Artificial Intelligence Image Enhancement. Gastroenterology. 2019 Aug; 157 (2):303-305 Epub 2019 May 09
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  64. Kamboj AK, Nehra V, Leggett CL. Hidden in Plain Sight. Gastroenterology. 2019 Jun; 156 (8):2144-2145 Epub 2019 Feb 27
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  65. Ajayi OD, Leggett CL, Myburgh SJ, Hendriksen SM, Logue CJ, Walter JW, Masters TC, Westgard BC. Esophageal Stricture Following Radiation, Concurrent Immunochemotherapy, Treated With Hyperbaric Oxygen and Dilation. Mayo Clin Proc Innov Qual Outcomes. 2019 Jun; 3(2):241-245. Epub 2019 May 27.
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  66. Schupack DA, Lenz CJ, Geno DM, Tholen CJ, Leggett CL, Katzka DA, Alexander JA. The evolution of treatment and complications of esophageal food impaction. United European Gastroenterol J. 2019 May; 7 (4):548-556 Epub 2019 Mar 05
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  67. Al-Bawardy B, Kamboj AK, Desai S, Gorospe E, Bruining DH, Gostout CJ, Hansel SL, Larson MV, Murray JA, Nehra V, Leggett CL, Szarka LA, Watson RE, Rajan E. Patient-oriented education and visual-aid intervention are inadequate to identify patients with potential capsule retention: a prospective randomized study. Scand J Gastroenterol. 2019 May; 54 (5):662-665 Epub 2019 Apr 29
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  68. Kamboj AK, Hoversten P, Leggett CL. Upper Gastrointestinal Bleeding: Etiologies and Management. Mayo Clin Proc. 2019 Apr; 94 (4):697-703
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  69. Kahn A, Kamboj AK, Muppa P, Sawas T, Lutzke LS, Buras MR, Golafshar MA, Katzka DA, Iyer PG, Smyrk TC, Wang KK, Leggett CL. Staging of T1 esophageal adenocarcinoma with volumetric laser endomicroscopy: a feasibility study. Endosc Int Open. 2019 Apr; 7 (4):E462-E470 Epub 2019 Mar 21
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  70. Kamboj AK, Kahn A, Sawas T, Lutzke LS, Iyer PG, Wang KK, Leggett CL. Outcome of endoscopic mucosal resection in Barrett's esophagus determined by systematic quantification of epithelial glands using volumetric laser endomicroscopy. Gastrointest Endosc. 2019 Apr; 89 (4):701-708.e1 Epub 2018 Oct 16
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  71. Storm AC, Sawas T, Higgins T, Bruining DH, Leggett CL, Buttar NS, Wong Kee Song LM, Abu Dayyeh BK. Step-by-step use of hemostatic powder: treatment of a bleeding GI stromal tumor. VideoGIE. 2019 Jan; 4 (1):5-6 Epub 2018 Nov 23
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  72. Trindade AJ, Raphael KL, Inamdar S, Stewart M, Berkowitz J, Vegesna A, McKinley MJ, Benias PC, Kahn A, Leggett CL, Lee C, Sejpal DV, Rishi A. Volumetric laser endomicroscopy features of dysplasia at the gastric cardia in Barrett's oesophagus: results from an observational cohort study. BMJ Open Gastroenterol. 2019; 6 (1):e000340 Epub 2019 Oct 23
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  73. Sawas T, Visrodia KH, Zakko L, Lutzke LS, Leggett CL, Wang KK. Clutch cutter is a safe device for performing endoscopic submucosal dissection of superficial esophageal neoplasms: a western experience. Dis Esophagus. 2018 Nov 1; 31 (11)
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  74. Pouw RE, Beyna T, Belghazi K, Koch AD, Schoon EJ, Haidry R, Weusten BL, Bisschops R, Shaheen NJ, Wallace MB, Marcon N, Heise-Ginsburg R, Gotink AW, Wang KK, Leggett CL, Ortiz-Fernandez-Sordo J, Ragunath K, DiPietro M, Pech O, Neuhaus H, Bergman JJ. A prospective multicenter study using a new multiband mucosectomy device for endoscopic resection of early neoplasia in Barrett's esophagus. Gastrointest Endosc. 2018 Oct; 88 (4):647-654 Epub 2018 July 06
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  75. Kamboj AK, Kahn A, Wolfsen HC, Trindade AJ, Ganguly EK, Otaki F, Chan D, Zakko L, Visrodia K, Lutzke L, Wang KK, Leggett CL. Volumetric laser endomicroscopy interpretation and feature analysis in dysplastic Barrett's esophagus. J Gastroenterol Hepatol. 2018 Oct; 33 (10):1761-1765 Epub 2018 May 07
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  76. Sawas T, Iyer PG, Alsawas M, Cotton CC, Leggett CL, Murad MH, Wang KK, Shaheen NJ, Katzka DA. Higher Rate of Barrett's Detection in the First Year After Successful Endoscopic Therapy: Meta-analysis. Am J Gastroenterol. 2018 Jul; 113 (7):959-971 Epub 2018 June 14
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  77. Visrodia K, Zakko L, Singh S, Leggett CL, Iyer PG, Wang KK. Cryotherapy for persistent Barrett's esophagus after radiofrequency ablation: a systematic review and meta-analysis. Gastrointest Endosc. 2018 Jun; 87 (6):1396-1404.e1 Epub 2018 Feb 22
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  78. Trindade AJ, Inamdar S, Smith MS, Rosen L, Han D, Chang KJ, Leggett CL, Lightdale CJ, Pleskow DK, Sejpal DV, Tearney GJ, Thomas RM, Wallace MB. Correction: Learning curve and competence for volumetric laser endomicroscopy in Barrett's esophagus using cumulative sum analysis. Endoscopy. 2018 May; 50 (5):C10 Epub 2018 July 27
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  79. Trindade AJ, Inamdar S, Smith MS, Rosen L, Han D, Chang KJ, Leggett CL, Lightdale CJ, Pleskow DK, Sejpal DV, Tearney GJ, Thomas RM, Wallace MB. Learning curve and competence for volumetric laser endomicroscopy in Barrett's esophagus using cumulative sum analysis. Endoscopy. 2018 May; 50 (5):471-478 Epub 2017 Nov 27
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  80. Kamboj AK, Muppa P, Zakko L, Wang KK, Leggett CL. Use of volumetric laser endomicroscopy to characterize a duodenal neuroendocrine tumor. Gastrointest Endosc. 2018 Mar; 87 (3):894-895 Epub 2017 Sept 18
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  81. Tsai TH, Leggett CL, Trindade AJ, Sethi A, Swager AF, Joshi V, Bergman JJ, Mashimo H, Nishioka NS, Namati E. Optical coherence tomography in gastroenterology: a review and future outlook. J Biomed Opt. 2017 Dec; 22 (12):1-17
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  82. Thompson AJ, Hughes M, Anastasova S, Conklin LS, Thomas T, Leggett C, Faubion WA, Miller TJ, Delaney P, Lacombe F, Loiseau S, Meining A, Richards-Kortum R, Tearney GJ, Kelly P, Yang GZ. Position paper: The potential role of optical biopsy in the study and diagnosis of environmental enteric dysfunction. Nat Rev Gastroenterol Hepatol. 2017 Dec; 14 (12):727-738 Epub 2017 Nov 15
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  84. Trindade AJ, Leggett CL, Chang KJ. Volumetric laser endomicroscopy in the management of Barrett's esophagus. Curr Opin Gastroenterol. 2017 Jul; 33 (4):254-260
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  85. Jansson-Knodell CL, Codipilly DC, Leggett CL. Making Dysphagia Easier to Swallow: A Review for the Practicing Clinician. Mayo Clin Proc. 2017 Jun; 92 (6):965-972
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  86. Swager AF, Tearney GJ, Leggett CL, van Oijen MGH, Meijer SL, Weusten BL, Curvers WL, Bergman JJGHM. Identification of volumetric laser endomicroscopy features predictive for early neoplasia in Barrett's esophagus using high-quality histological correlation. Gastrointest Endosc. 2017 May; 85 (5):918-926.e7 Epub 2016 Sept 19
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  87. Chan DK, Zakko L, Visrodia KH, Leggett CL, Lutzke LS, Clemens MA, Allen JD, Anderson MA, Wang KK. Breath Testing for Barrett's Esophagus Using Exhaled Volatile Organic Compound Profiling With an Electronic Nose Device. Gastroenterology. 2017 Jan; 152 (1):24-26 Epub 2016 Nov 05
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  88. DaVee T, Irani S, Leggett CL, Berzosa Corella M, Grooteman KV, Wong Kee Song LM, Wallace MB, Kozarek RA, Baron TH. Stent-in-stent technique for removal of embedded partially covered self-expanding metal stents. Surg Endosc. 2016 Jun; 30 (6):2332-41 Epub 2015 Sept 28
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  89. Leggett CL, Gorospe EC, Chan DK, Muppa P, Owens V, Smyrk TC, Anderson M, Lutzke LS, Tearney G, Wang KK. Comparative diagnostic performance of volumetric laser endomicroscopy and confocal laser endomicroscopy in the detection of dysplasia associated with Barrett's esophagus. Gastrointest Endosc. 2016 May; 83 (5):880-888.e2 Epub 2015 Sept 03
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  90. Chan DK, Leggett CL, Wang KK. Diagnosing gastrointestinal illnesses using fecal headspace volatile organic compounds. World J Gastroenterol. 2016 Jan 28; 22 (4):1639-49
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  91. Tabibian JH, Leggett CL, Abu Dayyeh BK, Buttar NS. Endoluminal stenting via the suture-assisted flange engagement technique. Gastrointest Endosc. 2016 Jan; 83: (1)249-50.
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  92. Wolfsen HC, Sharma P, Wallace MB, Leggett C, Tearney G, Wang KK. Safety and feasibility of volumetric laser endomicroscopy in patients with Barrett's esophagus (with videos). Gastrointest Endosc. 2015 Oct; 82 (4):631-40 Epub 2015 May 06
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  93. Small AJ, Araujo JL, Leggett CL, Mendelson AH, Agarwalla A, Abrams JA, Lightdale CJ, Wang TC, Iyer PG, Wang KK, Rustgi AK, Ginsberg GG, Forde KA, Gimotty PA, Lewis JD, Falk GW, Bewtra M. Radiofrequency Ablation Is Associated With Decreased Neoplastic Progression in Patients With Barrett's Esophagus and Confirmed Low-Grade Dysplasia. Gastroenterology. 2015 Sep; 149 (3):567-76.e3; quiz e13-4 Epub 2015 Apr 24
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  94. Carlson DA, Ravi K, Kahrilas PJ, Gyawali CP, Bredenoord AJ, Castell DO, Spechler SJ, Halland M, Kanuri N, Katzka DA, Leggett CL, Roman S, Saenz JB, Sayuk GS, Wong AC, Yadlapati R, Ciolino JD, Fox MR, Pandolfino JE. Diagnosis of Esophageal Motility Disorders: Esophageal Pressure Topography vs. Conventional Line Tracing. Am J Gastroenterol. 2015 Jul; 110 (7):967-77; quiz 978 Epub 2015 June 02
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  95. Leggett CL, Lewis JT, Wu TT, Schleck CD, Zinsmeister AR, Dunagan KT, Lutzke LS, Wang KK, Iyer PG. Clinical and histologic determinants of mortality for patients with Barrett's esophagus-related T1 esophageal adenocarcinoma. Clin Gastroenterol Hepatol. 2015 Apr; 13 (4):658-64.e1-3 Epub 2014 Aug 20
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  96. Leggett CL, Iyer PG. Mucosal imaging advanced technologies in the gastrointestinal tract Techniques in Gastrointestinal Endoscopy. 2015; 17: (4)161-70.
  97. Leggett CL, Gorospe EC, Calvin AD, Harmsen WS, Zinsmeister AR, Caples S, Somers VK, Dunagan K, Lutzke L, Wang KK, Iyer PG. Obstructive sleep apnea is a risk factor for Barrett's esophagus. Clin Gastroenterol Hepatol. 2014 Apr; 12 (4):583-8.e1 Epub 2013 Sept 11
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  98. Leggett CL, Gorospe EC. Application of confocal laser endomicroscopy in the diagnosis and management of Barrett's esophagus. Ann Gastroenterol. 2014; 27 (3):193-199
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  99. Al-Bawardy B, Gorospe EC, Leggett C. Malignant mesothelioma presenting as dysphagia diagnosed by endoscopic ultrasound. Ann Gastroenterol. 2014; 27 (4):409
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  100. Leggett CL, Gorospe EC, Lutzke L, Anderson M, Wang KK. A new era: endoscopic tissue transplantation. Curr Opin Gastroenterol. 2013 Sep; 29 (5):495-500
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  101. Timmer MR, Sun G, Gorospe EC, Leggett CL, Lutzke L, Krishnadath KK, Wang KK. Predictive biomarkers for Barrett's esophagus: so near and yet so far. Dis Esophagus. 2013 Aug; 26 (6):574-81 Epub 2013 Jan 14
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  102. Sun G, Tian J, Gorospe EC, Johnson GB, Hunt CH, Lutzke LS, Leggett CL, Iyer PG, Wang KK. Utility of baseline positron emission tomography with computed tomography for predicting endoscopic resectability and survival outcomes in patients with early esophageal adenocarcinoma. J Gastroenterol Hepatol. 2013 Jun; 28(6):975-81.
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  103. Chandra S, Gorospe EC, Leggett CL, Wang KK. Barrett's esophagus in 2012: updates in pathogenesis, treatment, and surveillance. Curr Gastroenterol Rep. 2013 May; 15 (5):322
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  104. Leggett CL, Gorospe EC, Wang KK. Endoscopic therapy for Barrett's esophagus and early esophageal adenocarcinoma. Gastroenterol Clin North Am. 2013 Mar; 42 (1):175-85
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  105. Leggett CL, Nelsen EM, Tian J, Schleck CB, Zinsmeister AR, Dunagan KT, Locke GR 3rd, Wang KK, Talley NJ, Iyer PG. Metabolic syndrome as a risk factor for Barrett esophagus: a population-based case-control study. Mayo Clin Proc. 2013 Feb; 88 (2):157-65
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  107. Sun G, Anderson MA, Gorospe EC, Leggett CL, Lutzke LS, Wong Kee Song LM, Levy M, Wang KK. Synergistic effects of photodynamic therapy with HPPH and gemcitabine in pancreatic cancer cell lines. Lasers Surg Med. 2012 Nov; 44 (9):755-61 Epub 2012 Sept 27
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  108. Leggett CL, Gorospe EC, Murad H, Montori V, Baron TH, Wang KK. Photodynamic Therapy for Unresectable Cholangiocarcinoma: A Systemic Review and Meta-analysis. Photodiagnosis & Photodyn Therapy.Sept 2012;9:(3):189-95.
  109. Leggett CL, Gorospe EC, Murad MH, Montori VM, Baron TH, Wang KK. Photodynamic therapy for unresectable cholangiocarcinoma: a comparative effectiveness systematic review and meta-analyses. Photodiagnosis Photodyn Ther. 2012 Sep; 9 (3):189-95 Epub 2012 Apr 11
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  110. Leggett CL, Prasad GA. High-grade dysplasia and intramucosal adenocarcinoma in Barrett's esophagus: the role of endoscopic eradication therapy. Curr Opin Gastroenterol. 2012 Jul; 28 (4):354-61
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  111. Leggett CL, McGehee DS, Mastrianni J, Yang W, Bai T, Boroson JR. Tunicamycin Produces TDP-43 Cytoplasmic Includions in Cultured Brain Organotypic Slices. J Neurol Sci.2012 Jun;317:(1-2):66-73.
  112. Gorospe EC, Leggett CL. Mesalazine-induced interstitial nephritis in a patient with ulcerative colitis. BMJ Case Rep. 2012 Feb 25; 2012
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  113. Gorospe EC, Leggett CL, Sun G. Inferior Mesenteric Arteriovenous Malformation: An Unusual Cause of Ischemic Colitis. Annals of Gastroenterology.2012;25:(2):165.
  114. Gorospe EC, Leggett CL, Nadkarni NA. Massive Biloma Presenting as Gastric Outlet Obstruction. Annals of Gastroenterology.2012;25:(2):166.
  115. Saleem A, Leggett CL, Murad MH, Baron TH. Meta-analysis of randomized trials comparing the patency of covered and uncovered self-expandable metal stents for palliation of distal malignant bile duct obstruction. Gastrointest Endosc. 2011 Aug; 74 (2):321-327.e1-3 Epub 2011 June 17
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