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Brian E. Lacy, M.D., Ph.D.

  1. Gastroenterologist
  2. Neurogastroenterologist
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Publications

  1. Lacy BE, Xu Y, Taylor DCA, Kosch KJ, Dobrescu R, Morlock A, Morlock R, Rooker C. Burden of illness and treatment attitudes among participants meeting Rome IV criteria for irritable bowel syndrome: A nationwide survey in the United States. Neurogastroenterol Motil. 2024 Nov; 36 (11):e14903 Epub 2024 Sept 02
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  2. Olson CG, Travers P, Lacy BE. Current opinion: functional dyspepsia. Curr Opin Gastroenterol. 2024 Nov 1; 40 (6):470-476 Epub 2024 June 12
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  3. Lacy BE, Cangemi DJ. Opioids and the Gastrointestinal Tract: The Role of Peripherally Active micro-Opioid Receptor Antagonists in Modulating Intestinal Permeability. Am J Gastroenterol. 2024 Oct 1; 119 (10):1970-1978 Epub 2024 June 13
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  4. Lacy BE, Xu Y, Taylor DCA, Kosch KJ, Dobrescu R, Morlock A, Morlock R, Rooker C. Treatment for chronic idiopathic constipation: Use and satisfaction from a nationwide survey of US participants. Neurogastroenterol Motil. 2024 Oct; 36 (10):e14885 Epub 2024 Aug 18
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  5. Loeb L, Cangemi DC, Squire JD, Lacy BE. Clarifying the Hazy Concepts of Food Allergies and Sensitivities. Gastroenterol Hepatol (N Y). 2024 Oct; 20 (9):524-531
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  6. Lacy BE, Cangemi DJ, Accurso JM, Axelrod S, Axelrod L, Navalgund A. A novel pilot study to evaluate the efficacy and safety of a wireless patch system in patients with chronic nausea and vomiting. Neurogastroenterol Motil. 2024 Sep; 36 (9):e14862 Epub 2024 July 22
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  7. Aldhaleei WA, Bakheet N, Odah T, Jett H, Wallace MB, Lacy BE, Bhagavathula AS, Bi Y. The effect of virtual reality on perioperative pain management in patients undergoing gastrointestinal procedures and surgeries: a systematic review of clinical trials. J Gastrointest Surg. 2024 Aug 8 Epub 2024 Aug 08
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  8. Lacy BE, Wise JL, Cangemi DJ. Leaky Gut Syndrome: Myths and Management. Gastroenterol Hepatol (N Y). 2024 Aug; 20 (5):264-272
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  9. Lacy BE, Gagnon-Sanschagrin P, Heimanson Z, Bungay R, Bellefleur R, Guerin A, Bumpass B, Borroto D, Joseph G, Dashputre AA. Treatment-Free Interval: A Novel Approach to Assessing Real-World Treatment Effectiveness and Economic Impact Among Patients with Irritable Bowel Syndrome with Diarrhea. Adv Ther. 2024 Jun; 41 (6):2253-2266 Epub 2024 Apr 15
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  10. Lembo AJ, Chey WD, Harris LA, Frazier R, Brenner DM, Chang L, Lacy BE, Edelstein S, Yang Y, Zhao S, Rosenbaum DP. Abdominal Symptom Improvement During Clinical Trials of Tenapanor in Patients With Irritable Bowel Syndrome With Constipation: A Post Hoc Analysis. Am J Gastroenterol. 2024 May 1; 119 (5):937-945 Epub 2024 Jan 31
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  11. Bor S, Kalkan IH, Savarino E, Rao S, Tack J, Pasricha J, Cangemi D, Schol J, Karunaratne T, Ghisa M, Ahuja NK, Lacy B. Prokinetics-safety and efficacy: The European Society of Neurogastroenterology and Motility/The American Neurogastroenterology and Motility Society expert review. Neurogastroenterol Motil. 2024 May; 36 (5):e14774 Epub 2024 Mar 10
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  12. Tack J, Carbone F, Chang L, Lacy BE. Patient-Reported Outcomes in Disorders of Gut-Brain Interaction. Gastroenterology. 2024 Apr; 166 (4):572-587.e1 Epub 2024 Feb 01
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  13. Lacy BE. Managing IBS-C: Focus on Symptom Control. Gastroenterol Hepatol (N Y). 2024 Apr; 20 (4):216-226
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  14. Lacy BE, Cangemi DJ, Burke CA. Burnout in Gastrointestinal Providers. Am J Gastroenterol. 2024 Feb 16 [Epub ahead of print]
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  15. Cangemi DJ, Montenegro M, Spiegel BMR, Lacy ABE, Lacy BE. Virtual Reality Improves Symptoms of Functional Dyspepsia: Results of a Randomized, Double-Blind, Sham-Controlled, Pilot Study. Am J Gastroenterol. 2024 Jan 1; 119 (1):210-213 Epub 2023 Sept 01
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  16. Byale A, Lennon RJ, Byale S, Breen-Lyles M, Edwinson AL, Gupta R, Lacy BE, Olson JE, Houghton LA, Grover M. High-Dimensional Clustering of 4000 Irritable Bowel Syndrome Patients Reveals Seven Distinct Disease Subsets. Clin Gastroenterol Hepatol. 2024 Jan; 22 (1):173-184.e12 Epub 2022 Sept 27
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  17. Lacy BE, Delfini R, Fladung B, Lange R. Prevalence and patterns of laxative use in subjects with self-reported constipation: results from a multinational digestive health survey. Therap Adv Gastroenterol. 2024; 17:17562848241232605 Epub 2024 Mar 04
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  18. Travers P, Lacy BE, Cangemi DJ. Irritable bowel syndrome - less irritable, or better treatments? Curr Opin Gastroenterol. 2024 Jan 1; 40 (1):27-33 Epub 2023 Oct 19
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  19. Lacy BE, Rosenbaum D, Edelstein S, Kozuka K, Williams LA, Kunkel DC. Intestinal Permeability, Irritable Bowel Syndrome with Constipation, and the Role of Sodium-Hydrogen Exchanger Isoform 3 (NHE3). Clin Exp Gastroenterol. 2024; 17:173-183 Epub 2024 June 06
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  20. Lacy BE, Wise JL, Cangemi DJ. Gastroparesis: time for a paradigm change. Curr Opin Gastroenterol. 2023 Nov 1; 39 (6):503-511 Epub 2023 Sept 05
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  21. Cangemi DJ, Stephens L, Lacy BE. Misdiagnosis of Gastroparesis is Common: A Retrospective Review of Patients Referred to a Tertiary Gastroenterology Practice. Clin Gastroenterol Hepatol. 2023 Sep; 21 (10):2670-2672.e3 Epub 2023 Feb 03
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  22. Wise JL, Ingrosso MR, Ianiro G, Black CJ, Ford AC, Lacy BE. Response and Adverse Event Rates With Placebo in Gastroparesis: A Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol. 2023 Jun; 21 (6):1447-1461 Epub 2022 Oct 19
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  23. Brenner DM, Lacy BE, Ford AC, Bartolini W, Wu J, Shea EP, Bochenek W, Boinpally R, Almansa C. Linaclotide Reduced Response Time for Irritable Bowel Syndrome With Constipation Symptoms: Analysis of 4 Randomized Controlled Trials. Am J Gastroenterol. 2023 May 1; 118 (5):872-879 Epub 2022 Oct 12
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  24. Lacy BE, Keefer L, Drossman DA. De-escalate Don't Escalate: Essential Steps to Effectively Recognize and Manage the Patient Who Is Angry and Disruptive. Am J Gastroenterol. 2023 Mar 1; 118 (3):386-388 Epub 2022 Dec 07
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  25. Lacy BE, Chang L, Rao SSC, Heimanson Z, Sayuk GS. Rifaximin Treatment for Individual and Multiple Symptoms of Irritable Bowel Syndrome With Diarrhea: An Analysis Using New End Points. Clin Ther. 2023 Mar; 45 (3):198-209 Epub 2023 Mar 14
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  26. Lacy BE, Cangemi DJ, Spiegel BR. Virtual Reality: A New Treatment Paradigm for Disorders of Gut-Brain Interaction? Gastroenterol Hepatol (N Y). 2023 Feb; 19 (2):86-94
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  27. Quigley EMM, Markinson L, Stevenson A, Treasure FP, Lacy BE. Randomised clinical trial: efficacy and safety of the live biotherapeutic product MRx1234 in patients with irritable bowel syndrome. Aliment Pharmacol Ther. 2023 Jan; 57 (1):81-93 Epub 2022 Nov 11
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  28. Cangemi DJ, Lacy BE. Gastroparesis: Myths, Misconceptions, and Management. Clin Exp Gastroenterol. 2023; 16:65-78 Epub 2023 June 06
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  29. Lacy BE, Chase RC, Cangemi DJ. The treatment of functional dyspepsia: present and future. Expert Rev Gastroenterol Hepatol. 2023 Jan; 17 (1):9-20 Epub 2023 Jan 01
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  30. Lacy BE, King J, Shortino D, Schaumburg C, Haag-Molkenteller C, Chey WD. Efficacy and safety of vibegron for the treatment of irritable bowel syndrome in women: Results of a randomized, double-blind, placebo-controlled phase 2 trial. Neurogastroenterol Motil. 2022 Dec; 34 (12):e14448 Epub 2022 Aug 16
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  31. Lacy BE, Cangemi DJ. Updates in functional dyspepsia and bloating. Curr Opin Gastroenterol. 2022 Nov 1; 38 (6):613-619
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  32. Rao SSC, Lacy BE, Emmanuel A, Muller-Lissner S, Pohl D, Quigley EMM, Whorwell P. Recognizing and Defining Occasional Constipation: Expert Consensus Recommendations. Am J Gastroenterol. 2022 Nov 1; 117 (11):1753-1758 Epub 2022 Aug 12
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  33. Lacy BE, Cangemi DJ, Wise JL, Crowell MD. Development and validation of a novel scoring system for bloating and distension: The Mayo Bloating Questionnaire. Neurogastroenterol Motil. 2022 Aug; 34 (8):e14330 Epub 2022 Feb 24
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  34. Rangel Paniz G, Lebow J, Sim L, Lacy BE, Farraye FA, Werlang ME. Eating Disorders: Diagnosis and Management Considerations for the IBD Practice. Inflamm Bowel Dis. 2022 Jun 3; 28 (6):936-946
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  35. Lacy BE, Cangemi DJ. A Pragmatic Approach to the Evaluation and Treatment of Abdominal Bloating. Am J Gastroenterol. 2022 May 1; 117 (5):701-705 Epub 2022 Jan 29
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  36. Crowell MD, Umar SB, Lacy BE, Jones MP, DiBaise JK. factorial structure, validity and internal consistency of the multi dimensional gastrointestinal symptoms severity index (GISSI) Dig Dis Sci 2015. 2015; 60:2270-2279.
  37. Lacy BE, Brenner DM, Chey WD. Re-evaluation of the Cardiovascular Safety Profile of Tegaserod: A Review of the Clinical Data. Clin Gastroenterol Hepatol. 2022 Apr; 20 (4):e682-e695 Epub 2021 May 25
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  38. Lacy BE, Chey WD, Epstein MS, Shah SM, Corsino P, Zeitzoff LR, Cash BD. A novel duodenal-release formulation of caraway oil and L-menthol is a safe, effective and well tolerated therapy for functional dyspepsia. BMC Gastroenterol. 2022 Mar 7; 22 (1):105 Epub 2022 Mar 07
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  39. Lacy BE, Tack J, Gyawali CP. AGA Clinical Practice Update on Management of Medically Refractory Gastroparesis: Expert Review. Clin Gastroenterol Hepatol. 2022 Mar; 20 (3):491-500 Epub 2021 Oct 29
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  40. Cangemi DJ, Lacy BE. A Practical Approach to the Diagnosis and Treatment of Abdominal Bloating and Distension. Gastroenterol Hepatol (N Y). 2022 Feb; 18 (2):75-84
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  41. Cid-Ruzafa J, Lacy BE, Schultze A, Duong M, Lu Y, Raluy-Callado M, Donaldson R, Weissman D, Gomez-Lumbreras A, Ouchi D, Giner-Soriano M, Morros R, Ukah A, Pohl D. Linaclotide utilization and potential for off-label use and misuse in three European countries. Therap Adv Gastroenterol. 2022; 15:17562848221100946 Epub 2022 June 11
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  42. Longstreth GF, Patton HM, Lacy BE. How Your Writing Can Succeed: Getting a Manuscript Accepted by The American Journal of Gastroenterology. Am J Gastroenterol. 2022 Jan 1; 117 (1):11-15
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  43. Montenegro M, Werlang M, Nelson A, Lacy BE. High Resolution Esophageal Manometry in Asthmatics Submitted. 2022.
  44. Longstreth GF, Patton HM, Lacy BE. Achieving manuscript acceptance by the American Journal of Gastroenterology: advice to authors based on an anylysis of reasons for rejection AM J Gastroenterol. 2022; 117:11-15.
  45. Lacy BE, Crowell MD, Cangemi DJ, Lunsford TN, Simren M, Tack J. Diagnostic Evaluation of Gastric Motor and Sensory Disorders. Am J Gastroenterol. 2021 Dec 1; 116 (12):2345-2356
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  46. Moktan VP, Robelin K, Lacy BE. 70-Year-Old Man With Chronic Nausea and Vomiting. Mayo Clin Proc. 2021 Dec; 96 (12):3142-3146 Epub 2021 Oct 30
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  47. Cangemi DJ, Lacy BE. Gastroparesis. Curr Opin Gastroenterol. 2021 Nov 1; 37 (6):596-601
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  48. Zaver HB, Ghoz H, Malviya BJ, Brahmbhatt B, Palmer WC, Lacy BE, DeVault KR, Krishna M, Bi Y. Lymphocytic Esophagitis: Assessing Risk Factors and Clinical Outcomes. Dig Dis Sci. 2021 Nov; 66 (11):3976-3984 Epub 2020 Nov 20
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  49. Lacy BE, Spiegel B. The "Changing Landscapes" Special Edition. Am J Gastroenterol 2021 Oct 1; 116 (10):1969
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  50. Wise JL, Vazquez-Roque MI, McKinney CJ, Zickella MA, Crowell MD, Lacy BE. Gastric Emptying Scans: Poor Adherence to National Guidelines. Dig Dis Sci. 2021 Sep; 66 (9):2897-2906 Epub 2020 May 16
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  51. Chang L, Lacy BE, Moshiree B, Kassebaum A, Abel JL, Hanlon J, Bartolini W, Boinpally R, Bochenek W, Fox SM, Mallick M, Tripp K, Omniewski N, Shea E, Borgstein N. Efficacy of Linaclotide in Reducing Abdominal Symptoms of Bloating, Discomfort, and Pain: A Phase 3B Trial Using a Novel Abdominal Scoring System. Am J Gastroenterol. 2021 Sep 1; 116 (9):1929-1937
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  52. Lacy BE, Cangemi DJ. Controversies in Gastroparesis: Discussing the Sticky Points. Am J Gastroenterol. 2021 Aug 1; 116 (8):1572-1576
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  53. Ghoz H, Stancampiano FF, Valery JR, Nordelo K, Malviya B, Lacy BE, Francis D, DeVault K, Bouras E, Krishna M, Palmer WC. Extent of eosinophilic esophagitis predicts response to treatment. Endosc Int Open. 2021 Aug; 9 (8):E1234-E1242 Epub 2021 July 16
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  54. Brenner DM, Lacy BE. Antispasmodics for Chronic Abdominal Pain: Analysis of North American Treatment Options. Am J Gastroenterol. 2021 Aug 1; 116 (8):1587-1600
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  55. Shah ED, Lacy BE, Chey WD, Chang L, Brenner DM. Tegaserod for Irritable Bowel Syndrome With Constipation in Women Younger Than 65 Years Without Cardiovascular Disease: Pooled Analyses of 4 Controlled Trials. Am J Gastroenterol. 2021 Aug 1; 116 (8):1601-1611
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  56. Nelson AD, Black CJ, Houghton LA, Lugo-Fagundo NS, Lacy BE, Ford AC. Systematic review and network meta-analysis: efficacy of licensed drugs for abdominal bloating in irritable bowel syndrome with constipation. Aliment Pharmacol Ther. 2021 Jul; 54 (2):98-108 Epub 2021 June 11
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  57. Cangemi DJ, Lacy BE, Wise J. Diagnosing Small Intestinal Bacterial Overgrowth: A Comparison of Lactulose Breath Tests to Small Bowel Aspirates. Dig Dis Sci. 2021 Jun; 66 (6):2042-2050 Epub 2020 July 17
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  58. Jones J, Lembo A, Heidelbaugh J, Kuritzky L, Lacy B. Management of irritable bowel syndrome with diarrhea: focus on eluxadoline. Curr Med Res Opin. 2021 Apr; 37 (4):567-578 Epub 2021 Mar 03
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  59. Navas CM, Wadas ED, Zbib NH, Crowell MD, Lacy BE. Gastroparesis and Severity of Delayed Gastric Emptying: Comparison of Patient Characteristics, Treatments and Medication Adverse Events. Dig Dis Sci. 2021 Feb; 66 (2):526-534 Epub 2020 Apr 18
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  60. Lacy BE, Cangemi D, Vazquez-Roque M. Management of Chronic Abdominal Distension and Bloating. Clin Gastroenterol Hepatol. 2021 Feb; 19 (2):219-231.e1 Epub 2020 Apr 01
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  61. Shah SL, Janisch NH, Crowell M, Lacy BE. Patients With Irritable Bowel Syndrome Are Willing to Take Substantial Medication Risks for Symptom Relief. Clin Gastroenterol Hepatol. 2021 Jan; 19 (1):80-86 Epub 2020 Apr 11
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  62. Cash BD, Lacy BE, Watton C, Schoenfeld PS, Weissman D. Post-marketing reports of pancreatitis in eluxadoline-treated patients pre and post US label change. Therap Adv Gastroenterol. 2021; 14:17562848211001725 Epub 2021 Apr 10
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  63. Lacy BE, Pimentel M, Brenner DM, Chey WD, Keefer LA, Long MD, Moshiree B. ACG Clinical Guideline: Management of Irritable Bowel Syndrome. Am J Gastroenterol. 2021 Jan 1; 116 (1):17-44
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  64. Werlang ME, Sim LA, Lebow JR, Lacy BE. Assessing for Eating Disorders: A Primer for Gastroenterologists. Am J Gastroenterol. 2021 Jan 1; 116 (1):68-76
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  65. Lacy BE, Shea EP, Manuel M, Abel JL, Jiang H, Taylor DCA. Lessons learned: Chronic idiopathic constipation patient experiences with over-the-counter medications. PLoS One. 2021; 16 (1):e0243318 Epub 2021 Jan 11
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  66. Werlang M, Farraye F, Lacy BE. Eating disorders and inflammatory bowel disease Inflamm Bowel Dis 2021. 2021.
  67. Lacy BE, Cangtemi D, Vazquez-Roque M. bloating: mechanisms and management Clin Gastroenterol Hepatol. 2021; 19:21-231.
  68. Chris-Olaiya A, Palmer W, Stancampiano F, Lacy B, Heckman M, Chirila R, Nikpour N, Mcleod E, Ryan T, Maillis A, Vargas E, Bouras E. Medication use and polypharmacy in patients referred to a tertiary gastroenterology practice. Rom J Intern Med. 2020 Dec 1; 58 (4):228-232 Epub 2020 Dec 17
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  69. Lacy BE. Update on Irritable Bowel Syndrome Guidelines. Gastroenterol Hepatol (N Y). 2020 Dec; 16 (12):648-650
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  70. Ford AC, Mahadeva S, Carbone MF, Lacy BE, Talley NJ. Functional dyspepsia. Lancet. 2020 Nov 21; 396(10263):1689-1702. Epub 2020 Oct 10.
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  71. Cangemi DJ, Lacy BE. Gastroparesis and functional dyspepsia: different diseases or different ends of the spectrum? Curr Opin Gastroenterol. 2020 Nov; 36 (6):509-517
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  72. Miller AT, Matar R, Abu Dayyeh BK, Beran A, Vela MF, Lacy BE, Crowell MD, Geno DM, Lavey CJ, Katzka DA, Ravi K. Postobesity Surgery Esophageal Dysfunction: A Combined Cross-Sectional Prevalence Study and Retrospective Analysis. Am J Gastroenterol. 2020 Oct; 115 (10):1669-1680
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  73. Lacy BE. An Individualized, Case-Based Approach to the Management of Irritable Bowel Syndrome. J Fam Pract. 2020 Sep; 69 (7 Suppl):S8-S13
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  74. Bharucha AE, Lacy BE. Mechanisms, Evaluation, and Management of Chronic Constipation. Gastroenterology. 2020 Apr; 158 (5):1232-1249.e3 Epub 2020 Jan 13
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  75. Lacy BE, Cangemi DJ. Making the diagnosis of functional dyspepsia Gastroenterol Rev LatAm in press. 2020.
  76. Lacy BE. Patient-Centric Care of Diarrhea-Predominant Irritable Bowel Syndrome. J Fam Pract. 2019 Oct; 68 (8):S43-S48
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  77. Kroner PT, Tolaymat OA, Bowman AW, Abril A, Lacy BE. Gastrointestinal Manifestations of Rheumatological Diseases. Am J Gastroenterol. 2019 Sep; 114 (9):1441-1454
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  78. Snyder DL, Crowell MD, Horsley-Silva J, Ravi K, Lacy BE, Vela MF. Opioid-Induced Esophageal Dysfunction: Differential Effects of Type and Dose. Am J Gastroenterol. 2019 Sep; 114 (9):1464-1469
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  79. Cash BD, Lacy BE, Schoenfeld PS, Dove LS, Covington PS. Response to Lai. Am J Gastroenterol 2019 Jul; 114 (7):1177-1178
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  80. Lacy BE, Spiegel B. Introduction to the Gut Microbiome Special Issue. Am J Gastroenterol 2019 Jul; 114 (7):1013
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  81. Lacy BE, Everhart K, Crowell MD. Functional Dyspepsia: Clinical Symptoms, Psychological Findings, and GCSI Scores. Dig Dis Sci. 2019 May; 64 (5):1281-1287 Epub 2018 Oct 31
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  82. Chey WD, Lacy BE, Cash BD, Epstein M, Corsino PE, Shah SM. A Novel, Duodenal-Release Formulation of a Combination of Caraway Oil and L-Menthol for the Treatment of Functional Dyspepsia: A Randomized Controlled Trial. Clin Transl Gastroenterol. 2019 Apr; 10 (4):e00021
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  83. Lacy BE. Update on the management of chronic idiopathic constipation. Am J Manag Care. 2019 Mar; 25 (4 Suppl):S55-S62
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  84. Navas CM, Crowell MD, Lacy BE. The willingness of patients with gastroparesis to take risks with medications. Aliment Pharmacol Ther. 2019 Feb; 49(4):429-436. Epub 2019 Jan 09.
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  85. Pittayanon R, Yuan Y, Bollegala NP, Khanna R, Lacy BE, Andrews CN, Leontiadis GI, Moayyedi P. Prokinetics for Functional Dyspepsia: A Systematic Review and Meta-Analysis of Randomized Control Trials. Am J Gastroenterol. 2019 Feb; 114 (2):233-243
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  86. Lacy B, Ayyagari R, Guerin A, Lopez A, Shi S, Luo M. Factors associated with more frequent diagnostic tests and procedures in patients with irritable bowel syndrome. Therap Adv Gastroenterol. 2019; 12:1756284818818326 Epub 2019 Jan 01
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  87. Werlang ME, Palmer WC, Lacy BE. Irritable Bowel Syndrome and Dietary Interventions. Gastroenterol Hepatol (N Y). 2019 Jan; 15 (1):16-26
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  88. Lacy BE, Harris LA, Chang L, Lucak S, Gutman C, Dove LS, Covington PS, Lembo A. Impact of patient and disease characteristics on the efficacy and safety of eluxadoline for IBS-D: a subgroup analysis of phase III trials. Therap Adv Gastroenterol. 2019; 12:1756284819841290 Epub 2019 Apr 15
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  89. Navas CM, Patel NK, Lacy BE. Symptomatic Management of Gastroparesis. Gastrointest Endosc Clin N Am. 2019 Jan; 29 (1):55-70 Epub 2018 Sept 11
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  90. Lacy BE, Crowell MD, Camilleri M. The Challenges of Gastroparesis: Changing Study Design to Improve Clinical Care. Am J Gastroenterol. 2019 Jan; 114 (1):1-3
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  91. Ford AC, Lacy BE, Harris LA, Quigley EMM, Moayyedi P. Effect of Antidepressants and Psychological Therapies in Irritable Bowel Syndrome: An Updated Systematic Review and Meta-Analysis. Am J Gastroenterol. 2019 Jan; 114 (1):21-39
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  92. Cangemi DJ, Lacy BE. Management of irritable bowel syndrome with diarrhea: a review of nonpharmacological and pharmacological interventions. Therap Adv Gastroenterol. 2019; 12:1756284819878950 Epub 2019 Oct 04
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  93. Snyder DL, Crowell MD, Horsley-Silva J, Ravi K, Lacy BE, Vela MF. Effect of Opiod type and dosing on opioid induced esophageal dysfunction (OIED) AM J Gastroenterol. 2019; 114:1464-1469.
  94. Lacy BE, Spiegel B. Introduction to the 80% by 2018 Special Issue. Am J Gastroenterol 2018 Dec; 113 (12):1737-1738 Epub 2018 Oct 30
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  95. Ford AC, Harris LA, Lacy BE, Quigley EMM, Moayyedi P. Systematic review with meta-analysis: the efficacy of prebiotics, probiotics, synbiotics and antibiotics in irritable bowel syndrome. Aliment Pharmacol Ther. 2018 Nov; 48 (10):1044-1060 Epub 2018 Oct 08
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  96. Lacy BE. Review article: an analysis of safety profiles of treatments for diarrhoea-predominant irritable bowel syndrome. Aliment Pharmacol Ther. 2018 Oct; 48 (8):817-830 Epub 2018 Sept 07
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  97. Dionne J, Ford AC, Yuan Y, Chey WD, Lacy BE, Saito YA, Quigley EMM, Moayyedi P. A Systematic Review and Meta-Analysis Evaluating the Efficacy of a Gluten-Free Diet and a Low FODMAPs Diet in Treating Symptoms of Irritable Bowel Syndrome. Am J Gastroenterol. 2018 Sep; 113 (9):1290-1300 Epub 2018 July 26
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  98. Lacy BE. Practical Evaluation and Management of Irritable Bowel Syndrome with Diarrhea: A Case Study Approach. J Fam Pract. 2018 Aug; 67 (8 suppl):S31-S36
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  99. Yadlapati R, Vaezi MF, Vela MF, Spechler SJ, Shaheen NJ, Richter J, Lacy BE, Katzka D, Katz PO, Kahrilas PJ, Gyawali PC, Gerson L, Fass R, Castell DO, Craft J, Hillman L, Pandolfino JE. Management options for patients with GERD and persistent symptoms on proton pump inhibitors: recommendations from an expert panel. Am J Gastroenterol. 2018 Jul; 113 (7):980-986 Epub 2018 Apr 24
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  100. Ford AC, Moayyedi P, Chey WD, Harris LA, Lacy BE, Saito YA, Quigley EMM, ACG Task Force on Management of Irritable Bowel Syndrome. American College of Gastroenterology Monograph on Management of Irritable Bowel Syndrome. Am J Gastroenterol. 2018 Jun; 113 (Suppl 2):1-18
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  101. Lacy BE, Nicandro JP, Chuang E, Earnest DL. A prospective, multi center study of alosteron use in clinical practice: significant improvement in IBS symtpoms using the FDA composite endpoint Therapeutic ADV Gastroenterol. 2018.
  102. Lacy BE, Parkman HP, Camilleri M. Chronic nausea and vomiting: evaluation and treatment. Am J Gastroenterol. 2018 May; 113 (5):647-659 Epub 2018 Mar 15
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  103. Lacy BE, Chan JL. Physician Burnout: The Hidden Health Care Crisis. Clin Gastroenterol Hepatol. 2018 Mar; 16(3):311-317. Epub 2017 Jun 30.
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  104. Lacy BE, Ford AC, Talley NJ. Quality of Care and the Irritable Bowel Syndrome: Is Now the Time to Set Standards? Am J Gastroenterol. 2018 Feb; 113 (2):167-169 Epub 2017 Dec 05
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  105. Lacy BE, Saito YA, Camilleri M, Bouras E, DiBaise JK, Herrick LM, Szarka LA, Tilkes K, Zinsmeister AR, Talley NJ. Effects of Antidepressants on Gastric Function in Patients with Functional Dyspepsia. Am J Gastroenterol. 2018 Feb; 113 (2):216-224 Epub 2017 Dec 19
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  106. Lacy BE, Crowell MD, Mathis C, Bauer D, Heinberg LJ. Gastroparesis: Quality of Life and Health Care Utilization. J Clin Gastroenterol. 2018 Jan; 52 (1):20-24
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  107. Taylor F, Higgins S, Carson RT, Eremenco S, Foley C, Lacy BE, Parkman HP, Reasner DS, Shields AL, Tack J, Talley NJ. Development of a Symptom-Focused Patient-Reported Outcome Measure for Functional Dyspepsia: The Functional Dyspepsia Symptom Diary (FDSD). Am J Gastroenterol. 2018 Jan; 113 (1):39-48 Epub 2017 Sept 19
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  108. Schoenfeld P, Lacy BE, Chey WD, Lembo AJ, Kurtz CB, Reasner DS, Bochenek W, Tripp K, Currie MG, Fox SM, Blakesley RE, O'Dea CR, Omniewski ND, Hall ML. Low-Dose Linaclotide (72 mug) for Chronic Idiopathic Constipation: A 12-Week, Randomized, Double-Blind, Placebo-Controlled Trial. Am J Gastroenterol. 2018 Jan; 113 (1):105-114 Epub 2017 Aug 22
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  109. Lacy BE, Nicandro JP, Chuang E, Earnest DL. Alosetron use in clinical practice: significant improvement in irritable bowel syndrome symptoms evaluated using the US Food and Drug Administration composite endpoint. Therap Adv Gastroenterol. 2018; 11:1756284818771674 Epub 2018 May 08
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  110. Lacy BE, Crowell MD, Mathis C, Bauer D, Heinberg LJ. American College of Gastroenterolgy and Canadian Association of Gastroenterology guidelines onn the management of dyspepsia J Clin Gastroenterol. 2018; 52:20-24.
  111. Yadlapati R, Keswani RN, Ciolino JD, Grande DP, Listernick ZI, Carlson DA, Castell DO, Dunbar KB, Gawron AJ, Gyawali CP, Katz PO, Katzka D, Lacy BE, Spechler SJ, Tatum R, Vela MF, Pandolfino JE. A System to Assess the Competency for Interpretation of Esophageal Manometry Identifies Variation in Learning Curves. Clin Gastroenterol Hepatol. 2017 Nov; 15 (11):1708-1714.e3 Epub 2016 July 27
    View PubMed
  112. Lacy BE, Spiegel B. No Results? No Problem! Why We Are Publishing Methods of a Landmark Study With Results Still Pending. Am J Gastroenterol. 2017 Nov; 112 (11):1747-1748
    View PubMed
  113. Lacy BE, Patel NK. Rome Criteria and a Diagnostic Approach to Irritable Bowel Syndrome. J Clin Med. 2017 Oct 26; 6 (11)
    View PubMed
  114. Cash BD, Lacy BE, Schoenfeld PS, Dove LS, Covington PS. Safety of Eluxadoline in Patients With IBS-D Without a Gallbladder. Am J Gastroenterol. 2017 Oct; 112 (10):1619-1620
    View PubMed
  115. Cash BD, Lacy BE, Schoenfeld PS, Dove LS, Covington PS. Response to Croteau and Barkin. Am J Gastroenterol. 2017 Oct; 112 (10):1617
    View PubMed
  116. Navas CM, Patel NK, Lacy BE. Gastroparesis: Medical and Therapeutic Advances. Dig Dis Sci. 2017 Sep; 62 (9):2231-2240 Epub 2017 July 18
    View PubMed
  117. Moayyedi PM, Lacy BE, Andrews CN, Enns RA, Howden CW, Vakil N. Corrigendum: ACG and CAG Clinical Guideline: Management of Dyspepsia. Am J Gastroenterol. 2017 Sep; 112 (9):1484 Epub 2017 Aug 01
    View PubMed
  118. Lacy BE, Chey WD, Cash BD, Lembo AJ, Dove LS, Covington PS. Corrigendum: Eluxadoline Efficacy in IBS-D Patients Who Report Prior Loperamide Use. Am J Gastroenterol. 2017 Jul; 112 (7):1210 Epub 2017 May 30
    View PubMed
  119. Moayyedi PM, Lacy BE, Andrews CN, Enns RA, Howden CW, Vakil N. ACG and CAG Clinical Guideline: Management of Dyspepsia. Am J Gastroenterol. 2017 Jul; 112 (7):988-1013 Epub 2017 June 20
    View PubMed
  120. Ford AC, Lacy BE, Talley NJ. Irritable Bowel Syndrome. N Engl J Med. 2017 Jun 29; 376 (26):2566-2578
    View PubMed
  121. Saito YA, Locke GR, Almazar AE, Bouras EP, Howden CW, Lacy BE, DiBaise JK, Prather CM, Abraham BP, El-Serag HB, Moayyedi P, Herrick LM, Szarka LA, Camilleri M, Hamilton FA, Schleck CD, Tilkes KE, Zinsmeister AR, Talley NJ. Polymorphisms of 5-HTT LPR and GNß3 825C>T and Response to Antidepressant Treatment in Functional Dyspepsia: A Study from The Functional Dyspepsia Treatment Trial. Am J Gastroenterol. 2017 Jun; 112(6):903-909. Epub 2017 Mar 14.
    View PubMed
  122. Lacy BE, Chey WD, Cash BD, Lembo AJ, Dove LS, Covington PS. Eluxadoline Efficacy in IBS-D Patients Who Report Prior Loperamide Use. Am J Gastroenterol. 2017 Jun; 112 (6):924-932 Epub 2017 Apr 18
    View PubMed
  123. Lacy BE. Hot Topics in Primary Care: Role of the Microbiome in Disease: Implications for Treatment of Irritable Bowel Syndrome. J Fam Pract. 2017 Apr; 66 (4 Suppl):S40-S45
    View PubMed
  124. Koliani-Pace J, Lacy BE. Update on the Management of Chronic Constipation. Curr Treat Options Gastroenterol. 2017 Mar; 15 (1):126-134
    View PubMed
  125. Crowell MD, Umar SB, Griffing WL, DiBaise JK, Lacy BE, Vela MF. Esophageal Motor Abnormalities in Patients With Scleroderma: Heterogeneity, Risk Factors, and Effects on Quality of Life. Clin Gastroenterol Hepatol. 2017 Feb; 15 (2):207-213.e1 Epub 2016 Sept 06
    View PubMed
  126. Cash BD, Lacy BE, Schoenfeld PS, Dove LS, Covington PS. Safety of Eluxadoline in Patients with Irritable Bowel Syndrome with Diarrhea. Am J Gastroenterol. 2017 Feb; 112 (2):365-374 Epub 2016 Dec 06
    View PubMed
  127. Putra J, Muller KE, Hussain ZH, Parker S, Gabbard S, Brickley EB, Lacy BE, Rothstein R, Lisovsky M. Lymphocytic Esophagitis in Nonachalasia Primary Esophageal Motility Disorders: Improved Criteria, Prevalence, Strength of Association, and Natural History. Am J Surg Pathol. 2016 Dec; 40 (12):1679-1685
    View PubMed
  128. Shah SL, Lacy BE. Dietary Interventions and Irritable Bowel Syndrome: A Review of the Evidence. Curr Gastroenterol Rep. 2016 Aug; 18 (8):41
    View PubMed
  129. Lacy BE, Moreau JC. Diarrhea-predominant irritable bowel syndrome: Diagnosis, etiology, and new treatment considerations. J Am Assoc Nurse Pract. 2016 Jul; 28 (7):393-404
    View PubMed
  130. Lacy BE. Perspective: An easier diagnosis. Nature. 2016 May 19; 533 (7603):S107
    View PubMed
  131. Lacy BE. Effects of Opioids on Esophageal Dysfunction. Gastroenterol Hepatol (N Y). 2016 May; 12 (5):323-5
    View PubMed
  132. Yadlapati R, Gawron AJ, Keswani RN, Bilimoria K, Castell DO, Dunbar KB, Gyawali CP, Jobe BA, Katz PO, Katzka DA, Lacy BE, Massey BT, Richter JE, Schnoll-Sussman F, Spechler SJ, Tatum R, Vela MF, Pandolfino JE. Identification of Quality Measures for Performance of and Interpretation of Data From Esophageal Manometry. Clin Gastroenterol Hepatol. 2016 Apr; 14 (4):526-534.e1 Epub 2015 Oct 20
    View PubMed
  133. Levenick JM, Gordon SR, Fadden LL, Levy LC, Rockacy MJ, Hyder SM, Lacy BE, Bensen SP, Parr DD, Gardner TB. Rectal Indomethacin Does Not Prevent Post-ERCP Pancreatitis in Consecutive Patients. Gastroenterology. 2016 Apr; 150 (4):911-7; quiz e19 Epub 2016 Jan 09
    View PubMed
  134. Mearin F, Lacy BE, Chang L, Chey WD, Lembo AJ, Simren M, Spiller R. Bowel Disorders. Gastroenterology. 2016 Feb 18 [Epub ahead of print]
    View PubMed
  135. Lembo AJ, Lacy BE, Zuckerman MJ, Schey R, Dove LS, Andrae DA, Davenport JM, McIntyre G, Lopez R, Turner L, Covington PS. Eluxadoline for Irritable Bowel Syndrome with Diarrhea. N Engl J Med. 2016 Jan 21; 374 (3):242-53
    View PubMed
  136. Cash BD, Lacy BE, Rao T, Earnest DL. Rifaximin and eluxadoline - newly approved treatments for diarrhea-predominant irritable bowel syndrome: what is their role in clinical practice alongside alosetron? Expert Opin Pharmacother. 2016; 17(3):311-22. Epub 2015 Dec 08.
    View PubMed
  137. Lacy BE, Spiegel B. The American Journal of Gastroenterology in 2016: Where Have We Been? Where Are We Going? Am J Gastroenterol. 2016 Jan; 111 (1):1-3 Epub 2016 Jan 12
    View PubMed
  138. Lacy BE. Diagnosis and treatment of diarrhea-predominant irritable bowel syndrome. Int J Gen Med. 2016; 9:7-17 Epub 2016 Feb 11
    View PubMed
  139. Lacy BE, Patel H, Guerin A, Dea K, Scopel JL, Alaghband R, Wu EQ, Mody R. Variation in Care for Patients with Irritable Bowel Syndrome in the United States. PLoS One. 2016; 11 (4):e0154258 Epub 2016 Apr 26
    View PubMed
  140. Lacy BE. Eluxadoline: A novel treament for diarrhea predominant IBS Neurogastroenterol Motil. 2016; 28:26-35.
  141. Lacy BE. Neuroenteric Stimulation for Gastroparesis. Curr Treat Options Gastroenterol. 2015 Dec; 13 (4):409-17
    View PubMed
  142. Shah SL, Lacy BE, DiBaise JK, Vela MF, Crowell MD. The impact of obesity on oesophageal acid exposure time on and off proton pump inhibitor therapy. Aliment Pharmacol Ther. 2015 Nov; 42(9):1093-100. Epub 2015 Sep 08.
    View PubMed
  143. Lacy BE. The Science, Evidence, and Practice of Dietary Interventions in Irritable Bowel Syndrome. Clin Gastroenterol Hepatol. 2015 Nov; 13 (11):1899-906 Epub 2015 Mar 10
    View PubMed
  144. Xue Y, Suriawinata A, Liu X, Li Z, Gabbard S, Rothstein R, Lacy B, Lisovsky M. Lymphocytic Esophagitis With CD4 T-cell-predominant Intraepithelial Lymphocytes and Primary Esophageal Motility Abnormalities: A Potential Novel Clinicopathologic Entity. Am J Surg Pathol. 2015 Nov; 39 (11):1558-67
    View PubMed
  145. Hussain ZH, Henderson EE, Maradey-Romerao C, George N, Fass R, Lacy BE. The Proton Pump Inhibitor Non-Responder: A Clinical Conundrum. Clin Transl Gastroenterol. 2015 Oct 8; 6:e115 Epub 2015 Oct 08
    View PubMed
  146. Moayyedi P, Quigley EM, Lacy BE, Lembo AJ, Saito YA, Schiller LR, Soffer EE, Spiegel BM, Ford AC. The Effect of Dietary Intervention on Irritable Bowel Syndrome: A Systematic Review. Clin Transl Gastroenterol. 2015 Aug 20; 6 (8):e107
    View PubMed
  147. Hussain ZH, Henderson EE, Maradey-Romerao C, George N, Fass R, Lacy BE. The Proton Pump Inhibitor Non-Responder: A Clinical Conundrum. Clin Transl Gastroenterol. 2015 Aug 13; 6:e106
    View PubMed
  148. Crowell MD, Umar SB, Lacy BE, Jones MP, DiBaise JK, Talley NJ. Multi-Dimensional Gastrointestinal Symptom Severity Index: Validation of a Brief GI Symptom Assessment Tool. Dig Dis Sci. 2015 Aug; 60 (8):2270-9 Epub 2015 Apr 05
    View PubMed
  149. Talley NJ, Locke GR, Saito YA, Almazar AE, Bouras EP, Howden CW, Lacy BE, DiBaise JK, Prather CM, Abraham BP, El-Serag HB, Moayyedi P, Herrick LM, Szarka LA, Camilleri M, Hamilton FA, Schleck CD, Tilkes KE, Zinsmeister AR. Effect of Amitriptyline and Escitalopram on Functional Dyspepsia: A Multicenter, Randomized Controlled Study. Gastroenterology. 2015 Aug; 149 (2):340-9.e2 Epub 2015 Apr 25
    View PubMed
  150. Stein B, Everhart KK, Lacy BE. Gastroparesis: A Review of Current Diagnosis and Treatment Options. J Clin Gastroenterol. 2015 Aug; 49 (7):550-8
    View PubMed
  151. Ratuapli SK, Crowell MD, DiBaise JK, Vela MF, Ramirez FC, Burdick GE, Lacy BE, Murray JA. Opioid-Induced Esophageal Dysfunction (OIED) in Patients on Chronic Opioids. Am J Gastroenterol. 2015 Jul; 110 (7):979-84 Epub 2015 June 02
    View PubMed
  152. Lacy BE. Proton Pump Inhibitor Nonresponders. Gastroenterol Hepatol (N Y). 2015 Jul; 11 (7):483-5
    View PubMed
  153. Lacy BE, Chey WD, Lembo AJ. New and Emerging Treatment Options for Irritable Bowel Syndrome. Gastroenterol Hepatol (N Y). 2015 Apr; 11 (4 Suppl 2):1-19
    View PubMed
  154. Hussain ZH, Everhart K, Lacy BE. Treatment of Chronic Constipation: Prescription Medications and Surgical Therapies. Gastroenterol Hepatol (N Y). 2015 Feb; 11 (2):104-14
    View PubMed
  155. Lacy BE, Yu J, Crowell MD. Medication risk-taking behavior in functional dyspepsia patients. Clin Transl Gastroenterol. 2015 Jan 8; 6:e69 Epub 2015 Jan 08
    View PubMed
  156. Lacy BE, Schey R, Shiff SJ, Lavins BJ, Fox SM, Jia XD, Blakesley RE, Hao X, Cronin JA, Currie MG, Kurtz CB, Johnston JM, Lembo AJ. Linaclotide in Chronic Idiopathic Constipation Patients with Moderate to Severe Abdominal Bloating: A Randomized, Controlled Trial. PLoS One. 2015; 10 (7):e0134349 Epub 2015 July 29
    View PubMed
  157. Hussain Z, Lacy BE, Fass R. The PPI non responder Clin Transl Gastroenterol. 2015; 106.
  158. Stein B, Everhart KK, Lacy BE. Treatment of functional dyspepsia and gastroparesis. Curr Treat Options Gastroenterol. 2014 Dec; 12 (4):385-97
    View PubMed
  159. Lacy BE, O'Shana T. Clinical pearls for irritable bowel syndrome: management of the diarrhea-predominant subtype. Gastroenterol Nurs. 2014 Nov-Dec; 37 (6):392-405
    View PubMed
  160. Ford AC, Quigley EM, Lacy BE, Lembo AJ, Saito YA, Schiller LR, Soffer EE, Spiegel BM, Moayyedi P. Efficacy of prebiotics, probiotics, and synbiotics in irritable bowel syndrome and chronic idiopathic constipation: systematic review and meta-analysis. Am J Gastroenterol. 2014 Oct; 109 (10):1547-61; quiz 1546, 1562 Epub 2014 July 29
    View PubMed
  161. Moayyedi P, Quigley EM, Lacy BE, Lembo AJ, Saito YA, Schiller LR, Soffer EE, Spiegel BM, Ford AC. The effect of fiber supplementation on irritable bowel syndrome: a systematic review and meta-analysis. Am J Gastroenterol. 2014 Sep; 109 (9):1367-74 Epub 2014 July 29
    View PubMed
  162. Ford AC, Quigley EM, Lacy BE, Lembo AJ, Saito YA, Schiller LR, Soffer EE, Spiegel BM, Moayyedi P. Effect of antidepressants and psychological therapies, including hypnotherapy, in irritable bowel syndrome: systematic review and meta-analysis. Am J Gastroenterol. 2014 Sep; 109 (9):1350-65; quiz 1366 Epub 2014 June 17
    View PubMed
  163. Hussain ZH, Whitehead DA, Lacy BE. Fecal impaction. Curr Gastroenterol Rep. 2014 Sep; 16 (9):404
    View PubMed
  164. Ford AC, Moayyedi P, Lacy BE, Lembo AJ, Saito YA, Schiller LR, Soffer EE, Spiegel BM, Quigley EM, Task Force on the Management of Functional Bowel Disorders. American College of Gastroenterology monograph on the management of irritable bowel syndrome and chronic idiopathic constipation. Am J Gastroenterol. 2014 Aug; 109 Suppl 1:S2-26; quiz S27
    View PubMed
  165. Ratuapli SK, Hansel SL, Umar SB, Burdick GE, Ramirez FC, Fleischer DE, Harris LA, Lacy BE, DiBaise JK, Crowell MD. Esophageal peristaltic defects in adults with functional dysphagia. Dysphagia. 2014 Aug; 29 (4):519-26 Epub 2014 June 04
    View PubMed
  166. Lacy BE, Hussain ZH, Mearin F. Treatment for constipation: new and old pharmacological strategies. Neurogastroenterol Motil. 2014 Jun; 26 (6):749-63
    View PubMed
  167. Gabbard SL, Lacy BE, Levine GM, Crowell MD. The impact of alcohol consumption and cholecystectomy on small intestinal bacterial overgrowth. Dig Dis Sci. 2014 Mar; 59 (3):638-44 Epub 2013 Dec 10
    View PubMed
  168. Lacy BE, Lembo AJ, Macdougall JE, Shiff SJ, Kurtz CB, Currie MG, Johnston JM. Responders vs clinical response: a critical analysis of data from linaclotide phase 3 clinical trials in IBS-C. Neurogastroenterol Motil. 2014 Mar; 26(3):326-33. Epub 2013 Dec 30.
    View PubMed
  169. Lacy BE, Chey WD, Chang L. An Evidence-Based Look at Misconceptions in the Treatment of Patients with IBS-D. Gastroenterol Hepatol (N Y). 2013 Nov; 9 (11 Suppl 5):1-24
    View PubMed
  170. Jobe BA, Richter JE, Hoppo T, Peters JH, Bell R, Dengler WC, DeVault K, Fass R, Gyawali CP, Kahrilas PJ, Lacy BE, Pandolfino JE, Patti MG, Swanstrom LL, Kurian AA, Vela MF, Vaezi M, DeMeester TR. Preoperative diagnostic workup before antireflux surgery: an evidence and experience-based consensus of the Esophageal Diagnostic Advisory Panel. J Am Coll Surg 2013 Oct; 217 (4):586-97 Epub 2013 Aug 21
    View PubMed
  171. Lacy BE, Wang F, Bhowal S, Schaefer E, study group. On-demand hyoscine butylbromide for the treatment of self-reported functional cramping abdominal pain. Scand J Gastroenterol. 2013 Aug; 48 (8):926-35
    View PubMed
  172. Lacy BE, Weiser KT, Kennedy AT, Crowell MD, Talley NJ. Functional dyspepsia: the economic impact to patients. Aliment Pharmacol Ther. 2013 Jul; 38(2):170-7. Epub 2013 Jun 03.
    View PubMed
  173. Gabbard SL, Lacy BE. Chronic intestinal pseudo-obstruction. Nutr Clin Pract. 2013 Jun; 28 (3):307-16 Epub 2013 Apr 23
    View PubMed
  174. Quigley EM, Lacy BE. Overlap of functional dyspepsia and GERD--diagnostic and treatment implications. Nat Rev Gastroenterol Hepatol. 2013 Mar; 10 (3):175-86 Epub 2013 Jan 08
    View PubMed
  175. Lacy BE. Functional dyspepsia and gastroparesis: one disease or two? Am J Gastroenterol. 2012 Nov; 107 (11):1615-20
    View PubMed
  176. Lacy BE, Levenick JM, Crowell MD. Linaclotide: a novel therapy for chronic constipation and constipation-predominant irritable bowel syndrome. Gastroenterol Hepatol (N Y). 2012 Oct; 8 (10):653-60
    View PubMed
  177. Mearin F, Lacy BE. Diagnostic criteria in IBS: useful or not? Neurogastroenterol Motil. 2012 Sep; 24(9):791-801.
    View PubMed
  178. Lacy BE, Levenick J, Crowell M. Recent advances in the management of difficult constipation. Curr Gastroenterol Rep. 2012 Aug; 14 (4):306-12
    View PubMed
  179. Lacy BE, Talley NJ, Locke GR 3rd, Bouras EP, DiBaise JK, El-Serag HB, Abraham BP, Howden CW, Moayyedi P, Prather C. Review article: current treatment options and management of functional dyspepsia. Aliment Pharmacol Ther. 2012 Jul; 36(1):3-15. Epub 2012 May 16.
    View PubMed
  180. Lacy BE, Levenick JM, Crowell M. Chronic constipation: new diagnostic and treatment approaches. Therap Adv Gastroenterol. 2012 Jul; 5 (4):233-47
    View PubMed
  181. Lacy BE, Everhart KK, Weiser KT, DeLee R, Strobel S, Siegel C, Crowell MD. IBS patients' willingness to take risks with medications. Am J Gastroenterol. 2012 Jun; 107 (6):804-9
    View PubMed
  182. Talley NJ, Locke GR 3rd, Herrick LM, Silvernail VM, Prather CM, Lacy BE, DiBaise JK, Howden CW, Brenner DM, Bouras EP, El-Serag HB, Abraham BP, Moayyedi P, Zinsmeister AR. Functional Dyspepsia Treatment Trial (FDTT): a double-blind, randomized, placebo-controlled trial of antidepressants in functional dyspepsia, evaluating symptoms, psychopathology, pathophysiology and pharmacogenetics. Contemp Clin Trials. 2012 May; 33(3):523-33. Epub 2012 Feb 10.
    View PubMed
  183. Ratuapli SK, Ellington TG, O'Neill MT, Umar SB, Harris LA, Foxx-Orenstein AE, Burdick GE, Dibaise JK, Lacy BE, Crowell MD. Proton pump inhibitor therapy use does not predispose to small intestinal bacterial overgrowth. Am J Gastroenterol. 2012 May; 107 (5):730-5 Epub 2012 Feb 14
    View PubMed
  184. Tack J, Camilleri M, Chang L, Chey WD, Galligan JJ, Lacy BE, Müller-Lissner S, Quigley EM, Schuurkes J, De Maeyer JH, Stanghellini V. Systematic review: cardiovascular safety profile of 5-HT(4) agonists developed for gastrointestinal disorders. Aliment Pharmacol Ther. 2012 Apr; 35(7):745-67. Epub 2012 Feb 22.
    View PubMed
  185. Lacy BE. Technical review: Utilization of pH monitoring technologies. Consensus statement from the Esophageal Diagnostic working Group Dis Esophagus. 2012.
  186. Lacy BE, Gabbard SL, Crowell MD. Pathophysiology, evaluation, and treatment of bloating: hope, hype, or hot air? Gastroenterol Hepatol (N Y). 2011 Nov; 7 (11):729-39
    View PubMed
  187. Lacy BE, Chehade R, Crowell MD. A prospective study to compare a symptom-based reflux disease questionnaire to 48-h wireless pH monitoring for the identification of gastroesophageal reflux (revised 2-26-11). Am J Gastroenterol. 2011 Sep; 106 (9):1604-11 Epub 2011 June 21
    View PubMed
  188. Lacy BE, Carter J, Weiss JE, Crowell MD. The effects of intraduodenal nutrient infusion on serum CCK, LES pressure, and gastroesophageal reflux. Neurogastroenterol Motil. 2011 Jul; 23(7):631-e256. Epub 2011 Mar 21.
    View PubMed
  189. Lacy BE, Dukowicz AC, Robertson DJ, Weiss JE, Teixeira P, Kelley ML Jr. Clinical utility of the wireless pH capsule. J Clin Gastroenterol. 2011 May-Jun; 45 (5):429-35
    View PubMed
  190. Lacy BE, Everhart K, Crowell MD. Functional dyspepsia is associated with sleep disorders. Clin Gastroenterol Hepatol. 2011 May; 9 (5):410-4 Epub 2011 Feb 17
    View PubMed
  191. Lacy BE, Dukowicz AC, Robertson DJ, Weiss JE, Kelley MLK. Clinical utility of the Bravo pH capsule Clin Gastroenterol. 2011; 45:429-435.
  192. Lacy BE. IBS Treatment: What's in the pipeline? Gastroenterol Hepatol. 2011.
  193. Lacy BE, Talley NJ, Camilleri M. Functional dyspepsia: time to change clinical trial design? Am J Gastroenterol. 2010 Dec; 105 (12):2525-9
    View PubMed
  194. Chang L, Lacy BE, Spiegel BM. An Evidence-based Approach to Therapy in IBS-D: A Case Study Compendium. Gastroenterol Hepatol (N Y). 2010 Sep; 6 (9 Suppl 15):1-12
    View PubMed
  195. Lacy BE, Weiser K, Chertoff J, Fass R, Pandolfino JE, Richter JE, Rothstein RI, Spangler C, Vaezi MF. The diagnosis of gastroesophageal reflux disease. Am J Med. 2010 Jul; 123 (7):583-92 Epub 2010 May 20
    View PubMed
  196. Gardner TB, Kennedy AT, Gelrud A, Banks PA, Vege SS, Gordon SR, Lacy BE. Chronic pancreatitis and its effect on employment and health care experience: results of a prospective American multicenter study. Pancreas. 2010 May; 39 (4):498-501
    View PubMed
  197. Lacy BE, Loew B, Crowell MD. Prucalopride for chronic constipation. Drugs Today (Barc). 2009 Dec; 45(12):843-53.
    View PubMed
  198. Kennedy AT, Weiser KT, Crowell MD, Talley NJ, Lacy BE. Functional dyspepsia: Validation and results of a novel survey instrument to evaluate patient knowledge and perceptions. J Clin Gastroenterol. 2009 Nov-Dec; 43 (10):933-40
    View PubMed
  199. Lacy BE, Paquette L, Robertson DJ, Kelley ML Jr, Weiss JE. The clinical utility of esophageal manometry. J Clin Gastroenterol. 2009 Oct; 43 (9):809-15
    View PubMed
  200. Lacy BE, Weiser K. Common anorectal disorders: diagnosis and treatment. Curr Gastroenterol Rep. 2009 Oct; 11(5):413-9.
    View PubMed
  201. Lacy Be, Loew B. chronic intestinal pseudo obstruction Pract Gastroenterol. 2009; 9-24.
  202. Lacy BE, Edwards S, Paquette L, Weiss J, Kelley ML Jr, Ornvold K. Tolerability and clinical utility of the Bravo pH capsule in children. J Clin Gastroenterol. 2009 Jul; 43 (6):514-9
    View PubMed
  203. Lacy BE, Weiser K, De Lee R. The treatment of irritable bowel syndrome. Therap Adv Gastroenterol. 2009 Jul; 2 (4):221-38
    View PubMed
  204. Lacy BE, Chey WD. Lubiprostone: chronic constipation and irritable bowel syndrome with constipation. Expert Opin Pharmacother. 2009 Jan; 10 (1):143-52
    View PubMed
  205. Lacy BE. A practical guide to irritable bowel syndrome-Alosetron HC1 (Lotronex)-Risk Gastroenterol Hepatolo Rev 2009. 2009; 5:62-67.
  206. Lacy BE, Mathis C, DesBiens J, Liu MC. The effects of nebulized albuterol on esophageal function in asthmatic patients. Dig Dis Sci. 2008 Oct; 53(10):2627-33. Epub 2008 Feb 13.
    View PubMed
  207. Lacy BE, Weiser K. Esophageal motility disorders: medical therapy. J Clin Gastroenterol. 2008 May-Jun; 42(5):652-8.
    View PubMed
  208. Lee WC, Yeh YC, Lacy BE, Pandolfino JE, Brill JV, Weinstein ML, Carlson AM, Williams MJ, Wittek MR, Pashos CL. Timely confirmation of gastro-esophageal reflux disease via pH monitoring: estimating budget impact on managed care organizations. Curr Med Res Opin. 2008 May; 24(5):1317-27. Epub 2008 Mar 27.
    View PubMed
  209. Lacy BE, Weiser K, Kennedy A. Botulinum toxin and gastrointestinal tract disorders: panacea, placebo, or pathway to the future? Gastroenterol Hepatol (N Y). 2008 Apr; 4 (4):283-95
    View PubMed
  210. Lacy BE, Cash BD. A 32-year-old woman with chronic abdominal pain. JAMA. 2008 Feb 6; 299 (5):555-65 Epub 2008 Jan 01
    View PubMed
  211. Lacy BE, Levy LC. Lubiprostone: a novel treatment for chronic constipation. Clin Interv Aging. 2008; 3 (2):357-64
    View PubMed
  212. Weiser KT, Lacy BE, Noddin L, Crowell MD. Patient knowledge and perspective on irritable bowel syndrome: development of a survey instrument. Dig Dis Sci. 2008 Jan; 53(1):284-95. Epub 2007 Jun 28.
    View PubMed
  213. Crowell MD, Schettler VA, Lacy BE, Lunsford TN, Harris LA, DiBaise JK, Jones MP. Impact of anal incontinence on psychosocial function and health-related quality of life. Dig Dis Sci. 2007 Jul; 52 (7):1627-31 Epub 2007 Jan 09
    View PubMed
  214. Lacy BE, Weiser K, Noddin L, Robertson DJ, Crowell MD, Parratt-Engstrom C, Grau MV. Irritable bowel syndrome: patients' attitudes, concerns and level of knowledge. Aliment Pharmacol Ther. 2007 Jun 01; 25(11):1329-41.
    View PubMed
  215. Lacy BE, Levy LC. Lubiprostone: a chloride channel activator. J Clin Gastroenterol. 2007 Apr; 41(4):345-51.
    View PubMed
  216. Dukowicz AC, Lacy BE, Levine GM. Small intestinal bacterial overgrowth: a comprehensive review. Gastroenterol Hepatol (N Y). 2007 Feb; 3 (2):112-22
    View PubMed
  217. Lacy BE, O'Shana T, Hynes M, Kelley ML Jr, Weiss JE, Paquette L, Rothstein RI. Safety and tolerability of transoral Bravo capsule placement after transnasal manometry using a validated conversion factor. Am J Gastroenterol. 2007 Jan; 102 (1):24-32 Epub 2006 Nov 13
    View PubMed
  218. Cash BD, Lacy BE. Systematic Review: FDA-Approved Prescription Medications for Adults With Constipation. Gastroenterol Hepatol (N Y). 2006 Oct; 2 (10):736-749
    View PubMed
  219. Lacy BE, Rosemore J, Robertson D, Corbin DA, Grau M, Crowell MD. Physicians' attitudes and practices in the evaluation and treatment of irritable bowel syndrome. Scand J Gastroenterol. 2006 Aug; 41 (8):892-902
    View PubMed
  220. Lacy BE. Lubiprostone for Chronic Constipation. Gastroenterol Hepatol (N Y). 2006 Jul; 2 (7):483
    View PubMed
  221. Lacy BE, Weiser K. Gastrointestinal motility disorders: an update. Dig Dis. 2006; 24 (3-4):228-42
    View PubMed
  222. Lacy BE, Weiser K. Gastric motility, gastroparesis, and gastric stimulation. Surg Clin North Am. 2005 Oct; 85 (5):967-87, vi-vii
    View PubMed
  223. Crowell MD, Mathis C, Schettler VA, Yunus T, Lacy BE. The effects of tegaserod, a 5-HT receptor agonist, on gastric emptying in a murine model of diabetes mellitus. Neurogastroenterol Motil. 2005 Oct; 17 (5):738-43
    View PubMed
  224. Noddin L, Callahan M, Lacy BE. Irritable bowel syndrome and functional dyspepsia: different diseases or a single disorder with different manifestations? MedGenMed. 2005 Aug 29; 7 (3):17
    View PubMed
  225. Ali MA, Lacy BE. Esophageal manometry and pH monitoring: gastroenterologists' adherence to published guidelines. J Clin Gastroenterol. 2005 Aug; 39 (7):584-90
    View PubMed
  226. Lacy BE, Crowell MD, Riesett RP, Mitchell A. Age, specialty, and practice setting predict gastroesophageal reflux disease prescribing behavior. J Clin Gastroenterol. 2005 Jul; 39 (6):489-94
    View PubMed
  227. Lacy BE, Lee RD. Irritable bowel syndrome: a syndrome in evolution. J Clin Gastroenterol. 2005 May-Jun; 39 (5 Suppl 3):S230-42
    View PubMed
  228. Lacy BE, Brunton SA. Partnering with gastroenterologists to evaluate patients with chronic constipation. MedGenMed. 2005 Apr 28; 7 (2):19
    View PubMed
  229. lacy BE. Clinial Advances in Upper GI functional Disorders Medscape General Medicine. 2005.
  230. Crowell MD, Lacy BE, Schettler VA, Dineen TN, Olden KW, Talley NJ. Subtypes of anal incontinence associated with bowel dysfunction: clinical, physiologic, and psychosocial characterization. Dis Colon Rectum. 2004 Oct; 47 (10):1627-35
    View PubMed
  231. Lacy BE, Crowell MD, Schettler-Duncan A, Mathis C, Pasricha PJ. The treatment of diabetic gastroparesis with botulinum toxin injection of the pylorus. Diabetes Care. 2004 Oct; 27(10):2341-7.
    View PubMed
  232. Rosemore J, Nikoomanesh P, Lacy BE. Bilateral temporomandibular joint dislocation after PEG tube placement. Gastrointest Endosc. 2004 Jan; 59(1):146-7.
    View PubMed
  233. Lacy BE, Cole MS. constipation in the older adult Clinical Geriatrics. 2004; 12:44-54.
  234. Talley NJ, Dennis EH, Schettler-Duncan VA, Lacy BE, Olden KW, Crowell MD. Overlapping upper and lower gastrointestinal symptoms in irritable bowel syndrome patients with constipation or diarrhea. Am J Gastroenterol. 2003 Nov; 98 (11):2454-9
    View PubMed
  235. Lacy BE. Irritable bowel syndrome: a primer on management. Rev Gastroenterol Disord. 2003; 3 Suppl 3:S32-42.
    View PubMed
  236. Lacy Be. Irritable bowel syndrome - An update for primary care physicians Rev Internal Medicine. 2003.
  237. Lacy BE, Zayat EN, Crowell MD. Case report: botulinum toxin in hypertensive lower esophageal sphincter: a manometric case study. Dysphagia. 2002 Winter; 17 (1):75-80
    View PubMed
  238. Rosemore JG, Lacy BE. Irritable bowel syndrome: basis of clinical management strategies. J Clin Gastroenterol. 2002 Jul; 35 (1 Suppl):S37-44
    View PubMed
  239. Lacy BE, Zayat EN, Crowell MD, Schuster MM. Botulinum toxin for the treatment of gastroparesis: a preliminary report. Am J Gastroenterol. 2002 Jun; 97 (6):1548-52
    View PubMed
  240. Moncur JT, Lacy BE, Longnecker DS. Mixed acinar-endocrine carcinoma arising in the ampulla of Vater. Hum Pathol. 2002 Apr; 33(4):449-51.
    View PubMed
  241. Pope GD, Goodney PP, Burchard KW, Proia RR, Olafsson A, Lacy BE, Burrows LJ. Peptic ulcer/stricture after gastric bypass: a comparison of technique and acid suppression variables. Obes Surg. 2002 Feb; 12 (1):30-3
    View PubMed
  242. Fuss IJ, Boirivant M, Lacy B, Strober W. The interrelated roles of TGF-beta and IL-10 in the regulation of experimental colitis. J Immunol. 2002 Jan 15; 168 (2):900-8
    View PubMed
  243. Lacy BE, Yu S. Tegaserod: a new 5-HT4 agonist. J Clin Gastroenterol. 2002 Jan; 34(1):27-33.
    View PubMed
  244. Pande H, Lacy BE, Crowell MD. Inflammatory causes of gastroparesis Dig Dis Sci. 2002; 47:2664-2668.
  245. Byrnes CK, Nass PH, Shim J, Duncan MD, Lacy B, Harmon JW. Novel nuclear shuttle peptide to increase transfection efficiency in esophageal mucosal cells. J Gastrointest Surg. 2002 Jan-Feb; 6 (1):37-42
    View PubMed
  246. Lacy Be. Tegaserod Clinical Perspectives in Gastroenterology. 2002; 5:251-255.
  247. Crowell MD, Zayat EN, Lacy BE, Schettler-Duncan A, Liu MC. The effects of an inhaled beta(2)-adrenergic agonist on lower esophageal function: a dose-response study. Chest. 2001 Oct; 120(4):1184-9.
    View PubMed
  248. Lacy BE, Rosemore J. Helicobacter pylori: ulcers and more: the beginning of an era. J Nutr. 2001 Oct; 131 (10):2789S-2793S
    View PubMed
  249. Lacy BE, Zayat E, Crowell MD. Generalized intestinal dysmotility in a patient with syringomyelia. Am J Gastroenterol. 2001 Apr; 96 (4):1282-5
    View PubMed
  250. Mussa FF, Younes Z, Tihan T, Lacy BE. Anasarca and small bowel obstruction secondary to endometriosis. J Clin Gastroenterol. 2001 Feb; 32 (2):167-71
    View PubMed
  251. Lacy BE, Toor A, Bensen SP, Rothstein RI, Maheshwari Y. Acute esophageal necrosis: report of two cases and a review of the literature. Gastrointest Endosc. 1999 Apr; 49 (4 Pt 1):527-32
    View PubMed
  252. Fox BS, Dordai D, Moore RL, Lacy BE. In vivo priming of helper T cells in the absence of B cell activation. J Immunol. 1989 Dec 15; 143 (12):3887-93
    View PubMed
  253. Lacy BE, Underhill CB. The hyaluronate receptor is associated with actin filaments. J Cell Biol. 1987 Sep; 105 (3):1395-404
    View PubMed
  254. Lacy BE, Underhill CB. A protein binding assay for hyaluronate. Anal Biochem. 1986 Nov 1; 158 (2):436-42
    View PubMed
  255. Lacy BE. Neural crest cell migration and the extracellular matrix J. Wash. Acad.Sci. 1983; 73:128-140.
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