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Christopher L. Kramer, M.D.

  1. Neurocritical Care Specialist
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Publications

  1. Khan M, Lee J, Kramer C, Bojaxhi E, Szymkiewicz E, Rabai F, Peel J, Ng L, Gauthier M, Nimma S, Fox WC, Freeman WD, Rabinstein A, Pingree M, Kissoon N, Reuter P, Dyer A, Pizzi MA, Gatica-Moris S, Lim D, Newman D, Busl KM, Smith CR, Troxel AB, Fava M, Illenberger N, Pop R, Yang W, Frota LM, Gao H, Shan G, Hoh BL, Maciel CB. Rationale and Design for the BLOCK-SAH Study (Pterygopalatine Fossa Block as an Opioid-Sparing Treatment for Acute Headache in Aneurysmal Subarachnoid Hemorrhage): A Phase II, Multicenter, Randomized, Double-Blinded, Placebo-Controlled Clinical Trial with a Sequential Parallel Comparison Design. Neurocrit Care. 2024 Aug 13 [Epub ahead of print]
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  2. Tsikvadze M, Machado De Villafane B, Rose M, Peacock S, Peel JB, Ng L, Kramer C, Freeman WD. Diffuse Cerebral Edema With Uncal Herniation Leading to Brain Death in Patient With Fulminant Susac syndrome: Rare Complication of Rare Disease. Neurohospitalist. 2024 Jan; 14 (1):87-94 Epub 2023 Aug 23
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  3. Tsikvadze M, Machado B, Rose M, Peacock S, Peel JB, Ng L, Kramer C, Freeman WD. Diffuse cerebral edema with uncal herniation leading to brain death in patient with fulminant Susac syndrome: Rare complication of rare disease The Neurohospitalist. 2023.
  4. Marcellino C, Kramer CL, Manno E, Wijdicks E, Siegel J, Fugate J, Gobeske K, Hawkes M, Hocker S, Datar S, Chakraborty T, Dang J, Lal A, Montgomery A, Flurin L, Litell J, Gajic O, Rabinstein A. Developing DELPHI expert consensus rules for a digital twin model of acute stroke care in the neuro critical care unit. BMC Neurol. 2023 Apr 22; 23 (1):161
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  5. Mansour A, Loggini A, El Ammar F, Ginat D, Awad IA, Lazaridis C, Kramer C, Vasenina V, Polster SP, Huang A, Olivera Perez H, Das P, Horowitz PM, Zakrison T, Hampton D, Rogers SO, Goldenberg FD. Cerebrovascular Complications in Early Survivors of Civilian Penetrating Brain Injury. Neurocrit Care. 2021 Jun; 34 (3):918-926 Epub 2020 Oct 06
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  6. Loggini A, Mansour A, El Ammar F, Tangonan R, Kramer CL, Goldenberg FD, Lazaridis C. Inversion of T Waves on Admission is Associated with Mortality in Spontaneous Intracerebral Hemorrhage. J Stroke Cerebrovasc Dis. 2021 Jun; 30 (6):105776 Epub 2021 Apr 08
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  7. Loggini A, Mansour A, El Ammar F, Lazaridis C, Kramer CL, Bulwa Z, Saleh Velez F, McCoy C, Goldenberg FD. Early Determinants of Neurocritical Care Unit Length of Stay in Patients with Spontaneous Intracerebral Hemorrhage. Neurocrit Care. 2021 Apr; 34 (2):485-491
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  8. Loggini A, El Ammar F, Darzi AJ, Mansour A, Kramer CL, Goldenberg FD, Lazaridis C. Effect of desmopressin on hematoma expansion in antiplatelet-associated intracerebral hemorrhage: A systematic review and meta-analysis. J Clin Neurosci. 2021 Apr; 86:116-121 Epub 2021 Feb 03
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  9. Loggini A, Tangonan R, El Ammar F, Mansour A, Kramer CL, Lazaridis C, Goldenberg FD. Neuroendocrine Dysfunction in the Acute Setting of Penetrating Brain Injury: A Systematic Review. World Neurosurg. 2021 Mar; 147:172-180.e1 Epub 2020 Dec 17
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  10. Loggini A, Ammar FE, Awad IA, Lazaridis C, Kramer CL, Kordeck C, McKoy C, Goldenberg FD, Mansour A. Temporal Evolution and Outcomes of Non-Traumatic Intracerebral Hemorrhage in Hospitalized Patients. J Stroke Cerebrovasc Dis. 2021 Mar; 30 (3):105584 Epub 2021 Jan 04
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  11. Loggini A, El Ammar F, Mansour A, Kramer CL, Goldenberg FD, Lazaridis C. Association between electrolyte levels at presentation and hematoma expansion and outcome in spontaneous intracerebral hemorrhage: A systematic review. J Crit Care. 2021 Feb; 61:177-185 Epub 2020 Nov 03
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  12. Loggini A, Kass-Hout T, Awad IA, El Ammar F, Kramer CL, Goldenberg FD, Lazaridis C, Mansour A. Case Report: Management of Traumatic Carotid-Cavernous Fistulas in the Acute Setting of Penetrating Brain Injury. Front Neurol. 2021; 12:715955 Epub 2022 Feb 11
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  13. Loggini A, Tangonan R, El Ammar F, Mansour A, Goldenberg FD, Kramer CL, Lazaridis C. The role of amantadine in cognitive recovery early after traumatic brain injury: A systematic review. Clin Neurol Neurosurg. 2020 Jul; 194:105815 Epub 2020 Mar 21
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  14. Chakraborty T, Kramer CL, Wijdicks EFM, Rabinstein AA. Dysautonomia in Guillain-Barre Syndrome: Prevalence, Clinical Spectrum, and Outcomes. Neurocrit Care. 2020 Feb; 32 (1):113-120
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  15. Loggini A, Martinez RC, Kramer CL. Cerebral Herniation from Hyperammonemic Cerebral Edema: A Potentially Reversible Neurological Emergency. Neurocrit Care. 2019 Jun; 30 (3):681-685
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  16. Yuen C, Kamson D, Soliven B, Kramer C, Goldenberg F, Rezania K. Severe Relapse of Vaccine-Induced Guillain-Barre Syndrome After Treatment With Nivolumab. J Clin Neuromuscul Dis. 2019 Jun; 20 (4):194-199
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  17. Kramer CL. Vascular Disorders of the Spinal Cord. Continuum (Minneap Minn). 2018 Apr; 24 (2, Spinal Cord Disorders):407-426
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  18. Kramer CL, Boon AJ, Harper CM, Goodman BP. Compound muscle action potential duration in critical illness neuromyopathy. Muscle Nerve. 2018 Mar; 57 (3):395-400 Epub 2017 July 05
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  19. Bonow RO, Brown AS, Gillam LD, Kapadia SR, Kavinsky CJ, Lindman BR, Mack MJ, Thourani VH, Dehmer GJ, Bonow RO, Lindman BR, Beaver TM, Bradley SM, Carabello BA, Desai MY, George I, Green P, Holmes DR Jr, Johnston D, Leipsic J, Mick SL, Passeri JJ, Piana RN, Reichek N, Ruiz CE, Taub CC, Thomas JD, Turi ZG, Doherty JU, Dehmer GJ, Bailey SR, Bhave NM, Brown AS, Daugherty SL, Dean LS, Desai MY, Duvernoy CS, Gillam LD, Hendel RC, Kramer CM, Lindsay BD, Manning WJ, Mehrotra P, Patel MR, Sachdeva R, Wann LS, Winchester DE, Allen JM, Aortic Stenosis Writing Group//Aortic Stenosis Rating Panel//Appropriate Use Criteria Task Force. ACC/AATS/AHA/ASE/EACTS/HVS/SCA/SCAI/SCCT/SCMR/STS 2017 Appropriate Use Criteria for the Treatment of Patients With Severe Aortic Stenosis: A Report of the American College of Cardiology Appropriate Use Criteria Task Force, American Association for Thoracic Surgery, American Heart Association, American Society of Echocardiography, European Association for Cardio-Thoracic Surgery, Heart Valve Society, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Societ J Am Soc Echocardiogr. 2018 Feb; 31 (2):117-147 Epub 2017 Dec 16
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  20. Kramer CL. Intensive Care Unit-Acquired Weakness. Neurol Clin. 2017 Nov; 35 (4):723-736
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  21. Kramer CL. ICU-Acquired Weakness Neurol Clin. 2017; 35(4):723-736.
  22. Expert Panel on Cardiac Imaging:, Vogel-Claussen J, Elshafee ASM, Kirsch J, Brown RKJ, Hurwitz LM, Javidan-Nejad C, Julsrud PR, Kramer CM, Krishnamurthy R, Laroia AT, Leipsic JA, Panchal KK, Shah AB, White RD, Woodard PK, Abbara S. ACR Appropriateness Criteria® Dyspnea-Suspected Cardiac Origin. J Am Coll Radiol. 2017 May; 14(5S):S127-S137.
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  23. Expert Panels on Cardiac and Thoracic Imaging:, Kirsch J, Brown RKJ, Henry TS, Javidan-Nejad C, Jokerst C, Julsrud PR, Kanne JP, Kramer CM, Leipsic JA, Panchal KK, Ravenel JG, Shah AB, Mohammed TL, Woodard PK, Abbara S. ACR Appropriateness Criteria® Acute Chest Pain-Suspected Pulmonary Embolism. J Am Coll Radiol. 2017 May; 14(5S):S2-S12.
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  24. Kramer CL, Pegoli M, Mandrekar J, Lanzino G, Rabinstein AA. Refining the Association of Fever with Functional Outcome in Aneurysmal Subarachnoid Hemorrhage. Neurocrit Care. 2017 Feb; 26 (1):41-47
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  25. Longobardo L, Kramer C, Carerj S, Zito C, Jain R, Suma V, Thohan V, Sulemanjee N, Downey FX, Khandheria BK. Role of Echocardiography in the Evaluation of Left Ventricular Assist Devices: the Importance of Emerging Technologies. Curr Cardiol Rep. 2016 Jul; 18 (7):62
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  26. Kramer CL, Wetzel DR, Wijdicks EF. Devastating Delayed Leukoencephalopathy Associated with Bath Salt Inhalation. Neurocrit Care. 2016 Jun; 24 (3):454-8
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  27. Scharf EL, Kramer CL, Rabinstein AA. Hemorrhage or Ischemia? The Importance of 'Spotting' it Right. Neurocrit Care. 2015 Aug; 23 (1):113-5
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  28. Gallo de Moraes A, Patel PA, Mahal E, Kramer CL, Diaz Soto JC, Moua T. Acute fever and seizure in a patient with recent atrial fibrillation ablation. Heart Lung. 2015 Jul-Aug; 44 (4):314-6 Epub 2015 May 26
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  29. Kramer CL, McCullough M, Wijdicks EF. Teaching video neuroimages: how to unmask respiratory strength confounded by facial diplegia. Neurology. 2015 Feb 24; 84(8):e57-8.
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  30. Singh TD, Kramer CL, Mandrekar J, Lanzino G, Rabinstein AA. Asymptomatic Carotid Stenosis: Risk of Progression and Development of Symptoms. Cerebrovasc Dis. 2015; 40 (5-6):236-43 Epub 2015 Oct 21
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  31. Karnatovskaia LV, Lee AS, Festic E, Kramer CL, Freeman WD. Effect of prolonged therapeutic hypothermia on intracranial pressure, organ function, and hospital outcomes among patients with aneurysmal subarachnoid hemorrhage. Neurocrit Care. 2014 Dec; 21 (3):451-61
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  32. Capampangan DJ, Lee-Ianotti JK, Riordan KC, Kramer CL. Teaching neuroImages: Hyperdense posterior cerebral artery sign. Neurology. 2014 Nov 11; 83: (20)e180-1.
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  33. Kramer CL, Rabinstein AA, Wijdicks EF, Hocker SE. Neurologist versus machine: is the pupillometer better than the naked eye in detecting pupillary reactivity. Neurocrit Care. 2014 Oct; 21 (2):309-11
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  34. Kramer CL, Wijdicks EF. Central neurogenic hyperventilation. Neurology. 2014 Jul 22; 83(4):376.
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  35. Kramer C, Freeman WD, Larson JS, Hoffman-Snyder C, Wellik KE, Hoffman-Snyder C, Demaerschalk BM, Wingerchuk DM. Therapeutic hypothermia for severe traumatic brain injury: a critically appraised topic. Neurologist. 2012 May; 18 (3):173-7
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  36. Kramer C, Aguilar MI, Hoffman-Snyder C, Wellik KE, Wingerchuk DM, Demaerschalk BM. Safety and efficacy of ultrasound-enhanced thrombolysis in the treatment of acute middle cerebral artery infarction: a critically appraised topic. Neurologist. 2011 Nov; 17: (6)346-51.
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  37. Chez MG, Burton Q, Dowling T, Chang M, Khanna P, Kramer C. Memantine as adjunctive therapy in children diagnosed with autistic spectrum disorders: an observation of initial clinical response and maintenance tolerability. J Child Neurol. 2007 May; 22(5):574-9.
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PST-20543167