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Mary Ellen Koran, M.D., Ph.D.

  1. Nuclear Medicine Specialist

Publications

  1. Lee YJ, van den Berg NS, Duan H, Azevedo EC, Ferri V, Hom M, Raymundo RC, Valencia A, Castillo J, Shen B, Zhou Q, Freeman L, Koran ME, Kaplan MJ, Colevas AD, Baik FM, Chin FT, Martin BA, Iagaru A, Rosenthal EL. 89Zr-panitumumab Combined With 18F-FDG PET Improves Detection and Staging of Head and Neck Squamous Cell Carcinoma. Clin Cancer Res. 2022 Oct 14; 28 (20):4425-4434
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  2. Beinat C, Patel CB, Haywood T, Murty S, Naya L, Castillo JB, Reyes ST, Phillips M, Buccino P, Shen B, Park JH, Koran MEI, Alam IS, James ML, Holley D, Halbert K, Gandhi H, He JQ, Granucci M, Johnson E, Liu DD, Uchida N, Sinha R, Chu P, Born DE, Warnock GI, Weissman I, Hayden-Gephart M, Khalighi M, Massoud TF, Iagaru A, Davidzon G, Thomas R, Nagpal S, Recht LD, Gambhir SS. A Clinical PET Imaging Tracer ([(18)F]DASA-23) to Monitor Pyruvate Kinase M2-Induced Glycolytic Reprogramming in Glioblastoma. Clin Cancer Res. 2021 Dec 1; 27 (23):6467-6478 Epub 2021 Sept 02
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  3. Chen KT, Toueg TN, Koran MEI, Davidzon G, Zeineh M, Holley D, Gandhi H, Halbert K, Boumis A, Kennedy G, Mormino E, Khalighi M, Zaharchuk G. True ultra-low-dose amyloid PET/MRI enhanced with deep learning for clinical interpretation. Eur J Nucl Med Mol Imaging. 2021 Jul; 48 (8):2416-2425 Epub 2021 Jan 08
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  4. Mormino EC, Toueg TN, Azevedo C, Castillo JB, Guo W, Nadiadwala A, Corso NK, Hall JN, Fan A, Trelle AN, Harrison MB, Hunt MP, Sha SJ, Deutsch G, James M, Fredericks CA, Koran ME, Zeineh M, Poston K, Greicius MD, Khalighi M, Davidzon GA, Shen B, Zaharchuk G, Wagner AD, Chin FT. Tau PET imaging with (18)F-PI-2620 in aging and neurodegenerative diseases. Eur J Nucl Med Mol Imaging. 2021 Jul; 48 (7):2233-2244 Epub 2020 June 23
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  5. Mahoney ER, Dumitrescu L, Moore AM, Cambronero FE, De Jager PL, Koran MEI, Petyuk VA, Robinson RAS, Goyal S, Schneider JA, Bennett DA, Jefferson AL, Hohman TJ. Brain expression of the vascular endothelial growth factor gene family in cognitive aging and alzheimer's disease. Mol Psychiatry. 2021 Mar; 26 (3):888-896 Epub 2019 July 22
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  6. Quon JL, Han M, Kim LH, Koran ME, Chen LC, Lee EH, Wright J, Ramaswamy V, Lober RM, Taylor MD, Grant GA, Cheshier SH, Kestle JRW, Edwards MSB, Yeom KW. Artificial intelligence for automatic cerebral ventricle segmentation and volume calculation: a clinical tool for the evaluation of pediatric hydrocephalus. J Neurosurg Pediatr. 2020 Dec 1; 27 (2):131-138 Epub 2020 Dec 01
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  7. Chen KT, Schurer M, Ouyang J, Koran MEI, Davidzon G, Mormino E, Tiepolt S, Hoffmann KT, Sabri O, Zaharchuk G, Barthel H. Generalization of deep learning models for ultra-low-count amyloid PET/MRI using transfer learning. Eur J Nucl Med Mol Imaging. 2020 Dec; 47 (13):2998-3007 Epub 2020 June 13
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  8. Reith F, Koran ME, Davidzon G, Zaharchuk G, Alzheimer's Disease Neuroimaging Initiative. Application of Deep Learning to Predict Standardized Uptake Value Ratio and Amyloid Status on (18)F-Florbetapir PET Using ADNI Data. AJNR Am J Neuroradiol. 2020 Jun; 41 (6):980-986 Epub 2020 June 04
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  9. Nobashi T, Zacharias C, Ellis JK, Ferri V, Koran ME, Franc BL, Iagaru A, Davidzon GA. Performance Comparison of Individual and Ensemble CNN Models for the Classification of Brain 18F-FDG-PET Scans. J Digit Imaging. 2020 Apr; 33 (2):447-455
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  10. Moore AM, Mahoney E, Dumitrescu L, De Jager PL, Koran MEI, Petyuk VA, Robinson RA, Ruderfer DM, Cox NJ, Schneider JA, Bennett DA, Jefferson AL, Hohman TJ. APOE epsilon4-specific associations of VEGF gene family expression with cognitive aging and Alzheimer's disease. Neurobiol Aging. 2020 Mar; 87:18-25 Epub 2019 Nov 05
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  11. Koran MEI, Wagener M, Hohman TJ, Alzheimer's Neuroimaging Initiative. Sex differences in the association between AD biomarkers and cognitive decline. Brain Imaging Behav. 2017 Feb; 11 (1):205-213
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  12. Koran ME, Stewart S, Baker JC, Lipnik AJ, Banovac F, Omary RA, Brown DB. Five percent dextrose maximizes dose delivery of Yttrium-90 resin microspheres and reduces rates of premature stasis compared to sterile water. Biomed Rep. 2016 Dec; 5 (6):745-748 Epub 2016 Nov 01
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  13. Koran ME, Lipnik AJ, Baker JC, Banovac F, Omary RA, Brown DB. Procedural Impact of a Dedicated Interventional Oncology Service Line in a National Cancer Institute Comprehensive Cancer Center. J Am Coll Radiol. 2016 Sep; 13 (9):1145-50 Epub 2016 June 11
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  14. Hohman TJ, Koran ME, Thornton-Wells TA, Alzheimer's Disease Neuroimaging Initiative. Genetic modification of the relationship between phosphorylated tau and neurodegeneration. Alzheimers Dement. 2014 Nov; 10 (6):637-645.e1 Epub 2014 Mar 20
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  15. Koran ME, Thornton-Wells TA, Jahanshad N, Glahn DC, Thompson PM, Blangero J, Nichols TE, Kochunov P, Landman BA. Impact of family structure and common environment on heritability estimation for neuroimaging genetics studies using Sequential Oligogenic Linkage Analysis Routines. J Med Imaging (Bellingham). 2014 Jun 27; 1 (1):014005
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  16. Hohman TJ, Koran ME, Thornton-Wells TA, Alzheimer's Neuroimaging Initiative. Interactions between GSK3beta and amyloid genes explain variance in amyloid burden. Neurobiol Aging. 2014 Mar; 35 (3):460-5 Epub 2013 Oct 08
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  17. Hohman TJ, Koran ME, Thornton-Wells TA, Alzheimer's Neuroimaging Initiative. Genetic variation modifies risk for neurodegeneration based on biomarker status. Front Aging Neurosci. 2014; 6:183 Epub 2014 Aug 04
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  18. Koran ME, Hohman TJ, Edwards CM, Vega JN, Pryweller JR, Slosky LE, Crockett G, Villa de Rey L, Meda SA, Dankner N, Avery SN, Blackford JU, Dykens EM, Thornton-Wells TA. Differences in age-related effects on brain volume in Down syndrome as compared to Williams syndrome and typical development. J Neurodev Disord. 2014; 6 (1):8 Epub 2014 Apr 09
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  19. Koran ME, Hohman TJ, Thornton-Wells TA. Genetic interactions found between calcium channel genes modulate amyloid load measured by positron emission tomography. Hum Genet. 2014 Jan; 133 (1):85-93 Epub 2013 Sept 12
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  20. Koran ME, Hohman TJ, Meda SA, Thornton-Wells TA. Genetic interactions within inositol-related pathways are associated with longitudinal changes in ventricle size. J Alzheimers Dis. 2014; 38 (1):145-54
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  21. Bruehl S, Denton JS, Lonergan D, Koran ME, Chont M, Sobey C, Fernando S, Bush WS, Mishra P, Thornton-Wells TA. Associations between KCNJ6 (GIRK2) gene polymorphisms and pain-related phenotypes. Pain. 2013 Dec; 154 (12):2853-2859 Epub 2013 Aug 28
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  22. Meda SA, Koran ME, Pryweller JR, Vega JN, Thornton-Wells TA, Alzheimer's Disease Neuroimaging Initiative. Genetic interactions associated with 12-month atrophy in hippocampus and entorhinal cortex in Alzheimer's Disease Neuroimaging Initiative. Neurobiol Aging. 2013 May; 34 (5):1518.e9-18 Epub 2012 Oct 27
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  23. Hohman TJ, Koran ME, Thornton-Wells T, Alzheimer's Neuroimaging Initiative. Epistatic genetic effects among Alzheimer's candidate genes. PLoS One. 2013; 8 (11):e80839 Epub 2013 Nov 18
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  24. Das R, Anderson N, Koran MI, Weidman JR, Mikkelsen TS, Kamal M, Murphy SK, Linblad-Toh K, Greally JM, Jirtle RL. Convergent and divergent evolution of genomic imprinting in the marsupial Monodelphis domestica. BMC Genomics. 2012 Aug 16; 13:394
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PST-20568212