Publications Print Zein SE, Tande AJ, Carr CM, Verdoorn JT, Diehn FE, Lahr BD, Kingsbury MJ, Freedman BA, Huddleston PM, Howard MT, Horna P, Berbari EF. The utility of disc space and vertebral body specimens cell count differential for the diagnosis of native vertebral osteomyelitis: a prospective cohort study. Eur J Clin Microbiol Infect Dis. 2024 Dec; 43 (12):2371-2381 Epub 2024 Oct 02 View PubMed Webb LM, Kenderian SS, Angeli AM, Howard MT, Wijdicks EF. Chronic Lymphocytic Leukemia Infiltrating in the Brain. Cureus. 2024 Nov; 16 (11):e74080 Epub 2024 Nov 20 View PubMed Chiu A, Dasari S, Nasr SH, Dispenzieri A, Dao LN, Dalland JC, Howard MT, Larson DP, Rech KL, Theis JD, Vrana JA, McPhail ED. Salivary gland amyloidosis: Proteomic identification and clinicopathologic characterization of 57 cases. Hum Pathol. 2024 Sep; 151:105628 Epub 2024 July 17 View PubMed Dalland JC, Dao LN, Dasari S, Theis JD, Chiu A, Rech KL, Howard MT, Grogan M, Hagen C, Bois MC, McPhail ED. Dual AApoAIV amyloidosis and ATTR amyloidosis arising in the same patient: a report of three cases. Amyloid. 2024 Jun; 31 (2):153-155 Epub 2023 Dec 15 View PubMed Gilani SI, Dasari S, Tekin B, Hernandez LH, Cheville JC, Jimenez RE, Rech KL, Dao LN, Howard MT, Dalland JC, Chiu A, Theis JD, Vrana JA, Grogan M, Thompson RH, Leibovich BC, Karnes RJ, Boorjian SA, Dispenzieri A, McPhail ED, Gupta S. Identification of amyloidosis of the urinary tract and prostate: Opportunities for early diagnosis & intervention in systemic disease. Hum Pathol. 2023 Dec; 142:62-67 Epub 2023 Nov 17 View PubMed Tekin B, Gilani SI, Dasari S, Theis JD, Rech KL, Dao LN, Cubilla AL, Herrera Hernandez LP, Jimenez RE, Cheville JC, Dispenzieri A, Howard MT, McPhail ED, Erickson LA, Guo R, Gupta S. Proteomic and Clinicopathologic Assessment of Penile Amyloidosis: A Single Institutional Review of 12 Cases. Am J Clin Pathol. 2023 Sep 1; 160 (3):303-313 View PubMed Hagen CE, Dasari S, Theis JD, Rech KL, Dao LN, Howard MT, Dispenzieri A, Chiu A, Dalland JC, Kurtin PJ, Gertz MA, Kourelis TV, Muchtar E, Vrana JA, McPhail ED. Gastrointestinal amyloidosis: an often unexpected finding with systemic implications. Hum Pathol. 2023 Sep; 139:27-36 Epub 2023 June 28 View PubMed Abdelmagid MG, Al-Kali A, Begna KH, Hogan WJ, Litzow MR, Fleti F, Mangaonkar AA, Patnaik MS, Elliott MA, Alkhateeb H, Shi M, Howard MT, Reichard KK, Ketterling RP, Shah M, Pardanani A, Gangat N, Tefferi A. Blast phase myeloproliferative neoplasm with prior exposure to ruxolitinib: comparative analysis of mutations and survival. Haematologica 2023 Sep 1; 108 (9):2542-2545 Epub 2023 Sept 01 View PubMed Chiu A, Dasari S, Kurtin PJ, Theis JD, Vrana JA, Rech KL, Dao LN, Howard MT, Dalland JC, McPhail ED. Proteomic Identification and Clinicopathologic Characterization of Splenic Amyloidosis. Am J Surg Pathol. 2023 Jan 1; 47 (1):74-80 Epub 2022 Aug 15 View PubMed Chiu A, Dasari S, Kurtin PJ, Theis JD, Vrana JA, Dispenzieri A, Rech KL, Dao LN, Howard MT, Grogan M, McPhail ED. Bone marrow amyloid: a comprehensive analysis of 1,469 samples, including amyloid type, clinical features, and morphologic distribution. Amyloid. 2022 Sep; 29 (3):156-164 Epub 2022 Feb 09 View PubMed Shi M, Timm MM, Howard MT, Jevremovic D, Yuan J, Greipp PT, Peterson JF, Roh DJ, Horna P, Olteanu H. Spurious CD34 expression in B-cell lymphoma due to nonspecific binding to PerCP-Cy5.5 fluorochrome conjugates: A rare phenomenon and a diagnostic pitfall. Cytometry B Clin Cytom 2022 Jul; 102 (4):326-328 Epub 2022 June 02 View PubMed Shi M, Timm MM, Howard MT, Jevremovic D, Yuan J, Greipp PT, Peterson JF, Roh DJ, Horna P, Olteanu H. Spurious CD34 expression in B-cell lymphoma due to nonspecific binding to PerCP-Cy5.5 fluorochrome conjugates: A rare phenomenon and a diagnostic pitfall. Cytometry B Clin Cytom. 2022 Jul; 102(4):326-328. Epub 2022 Jun 02. View PubMed Walsh C, Hunter A, Lasho T, Finke C, Ketterling R, Komrokji R, Tefferi A, Mangaonkar A, Howard M, Gangat N, Al-Kali A, Ali NA, Padron E, Patnaik MM. Differential prognostic impact of IDH1 and IDH2 mutations in chronic myelomonocytic leukemia. Leukemia. 2022 Jun; 36 (6):1693-1696 Epub 2022 Mar 29 View PubMed King RL, Gupta A, Kurtin PJ, Ding W, Call TG, Rabe KG, Kenderian SS, Leis JF, Wang Y, Schwager SM, Slager SL, Kay NE, Koehler A, Ansell SM, Inwards DJ, Habermann TM, Shi M, Hanson CA, Howard MT, Parikh SA. Chronic lymphocytic leukemia (CLL) with Reed-Sternberg-like cells vs Classic Hodgkin lymphoma transformation of CLL: does this distinction matter? Blood Cancer J. 2022 Jan 28; 12 (1):18 View PubMed Riaz T, Howard M, Diehn F, Tande AJ, Ross C, Huddleston P, Berbari E. Utility of disc space aspirate cell counts and differentials in the diagnosis of native vertebral osteomyelitis. J Bone Jt Infect. 2022; 7(5):213-219. Epub 2022 Oct 20. View PubMed Begna KH, Kittur J, Yui J, Gangat N, Patnaik MM, Al-Kali A, Elliott MA, Hogan WJ, Litzow MR, Hook CC, Wolanskyj AP, Howard MT, Hanson CA, Ketterling RP, Pardanani AD, Tefferi A. De novo isolated myeloid sarcoma: comparative analysis of survival in 19 consecutive cases. Br J Haematol. 2021 Nov; 195 (3):413-416 Epub 2021 Aug 03 View PubMed Buxeda A, Said S, Nasr SH, Soler MJ, Howard MT, Maguire LJ, Fervenza FC. Crystal-Induced Podocytopathy Producing Collapsing Focal Segmental Glomerulosclerosis in Monoclonal Gammopathy of Renal Significance: A Case Report. Kidney Med. 2021 Jul-Aug; 3 (4):659-664 Epub 2021 May 14 View PubMed King RL, Siaghani PJ, Wong K, Edlefsen K, Shane L, Howard MT, Reichard KK, Mai M, Viswanatha DS, Greipp PT, Goble TA, Ruiz M, Hara H. Novel t(1;8)(p31.3;q21.3) NFIA-RUNX1T1 Translocation in an Infant Erythroblastic Sarcoma. Am J Clin Pathol. 2021 Jun 17; 156 (1):129-138 View PubMed Carr RM, Vorobyev D, Lasho T, Marks DL, Tolosa EJ, Vedder A, Almada LL, Yurcheko A, Padioleau I, Alver B, Coltro G, Binder M, Safgren SL, Horn I, You X, Solary E, Balasis ME, Berger K, Hiebert J, Witzig T, Buradkar A, Graf T, Valent P, Mangaonkar AA, Robertson KD, Howard MT, Kaufmann SH, Pin C, Fernandez-Zapico ME, Geissler K, Droin N, Padron E, Zhang J, Nikolaev S, Patnaik MM. RAS mutations drive proliferative chronic myelomonocytic leukemia via a KMT2A-PLK1 axis. Nat Commun. 2021 May 18; 12 (1):2901 View PubMed Li M, Binder M, Lasho T, Ferrer A, Gangat N, Al-Kali A, Mangaonkar A, Elliott M, Litzow M, Hogan W, Pardanani A, Wolanskyj-Spinner A, Howard M, King RL, Shah M, Alkhateeb H, Begna K, Tefferi A, Finke C, Oliveira J, Ketterling R, Olteanu H, Patnaik MM. Clinical, molecular, and prognostic comparisons between CCUS and lower-risk MDS: a study of 187 molecularly annotated patients. Blood Adv. 2021 Apr 27; 5 (8):2272-2278 View PubMed Wudhikarn K, Loghavi S, Mangaonkar AA, Al-Kali A, Binder M, Carr R, Reichard K, Finke C, Howard M, Gangat N, Tefferi A, Komrokji R, Ali N, Lasho T, Ketterling R, Padron E, Patnaik MM. SF3B1-mutant CMML defines a predominantly dysplastic CMML subtype with a superior acute leukemia-free survival. Blood Adv 2020 Nov 24; 4 (22):5716-5721 View PubMed Saadalla A, Jara Aguirre J, Wockenfus AM, Kelley BR, Swanson RL, Howard MT, Karon BS. Evaluation of automated synovial fluid total cell count and percent polymorphonuclear leukocytes on a Sysmex XN-1000 analyzer for identifying patients at risk of septic arthritis. Clin Chim Acta. 2020 Nov; 510:416-420 Epub 2020 Aug 04 View PubMed Dasari S, Theis JD, Vrana JA, Rech KL, Dao LN, Howard MT, Dispenzieri A, Gertz MA, Hasadsri L, Highsmith WE, Kurtin PJ, McPhail ED. Amyloid Typing by Mass Spectrometry in Clinical Practice: a Comprehensive Review of 16,175 Samples. Mayo Clin Proc. 2020 Sep; 95 (9):1852-1864 View PubMed Lucas N, Duchmann M, Rameau P, Noel F, Michea P, Saada V, Kosmider O, Pierron G, Fernandez-Zapico ME, Howard MT, King RL, Niyongere S, Diop MK, Fenaux P, Itzykson R, Willekens C, Ribrag V, Fontenay M, Padron E, Soumelis V, Droin N, Patnaik MM, Solary E. Biology and prognostic impact of clonal plasmacytoid dendritic cells in chronic myelomonocytic leukemia. Leukemia. 2019 Oct; 33 (10):2466-2480 Epub 2019 Mar 20 View PubMed Fang H, Ketterling RP, Hanson CA, Pardanani A, Kurtin PJ, Chen D, Greipp PT, Howard MT, King RL, Van Dyke DL, Reichard KK. A Test Utilization Approach to the Diagnostic Workup of Isolated Eosinophilia in Otherwise Morphologically Unremarkable Bone Marrow: A Single Institutional Experience. Am J Clin Pathol. 2018 Oct 1; 150 (5):421-431 View PubMed Marinelli LM, Fang H, Howard MT, Hanson CA, Haack JJ, Eick EA, Allen RJ, Ruffridge DE, Byrne CM, King RL. Bone Marrow Biopsy Operator Experience and Impact on Aspirate, Biopsy, and Ancillary Testing Quality. Mayo Clin Proc Innov Qual Outcomes. 2018 Sep; 2 (3):241-247 Epub 2018 Aug 01 View PubMed Fang H, Kapoor P, Gonsalves WI, Frederick LA, Viswanatha D, Howard MT, He R, Morice WG 2nd, McPhail ED, Greipp PT, Ansell SM, Kyle RA, Gertz MA, Paludo J, Abeykoon J, King RL. Defining Lymphoplasmacytic Lymphoma: Does MYD88L265P Define a Pathologically Distinct Entity Among Patients With an IgM Paraprotein and Bone Marrow-Based Low-Grade B-Cell Lymphomas With Plasmacytic Differentiation? Am J Clin Pathol. 2018 Jul 3; 150 (2):168-176 View PubMed Reinig EF, Greipp PT, Chiu A, Howard MT, Reichard KK. De novo pure erythroid leukemia: refining the clinicopathologic and cytogenetic characteristics of a rare entity. Mod Pathol. 2018 May; 31 (5):705-717 Epub 2018 Jan 12 View PubMed Stitt DW, Boes CJ, Flanagan EP, Howard MT, Colgan JP. A Case of cutaneous large B-cell lymphoma during treatment of multiple sclerosis with fingolimod. Mult Scler Relat Disord. 2018 Jan; 19:115-117 Epub 2017 Nov 16 View PubMed Thanarajasingam U, Jensen MA, Dorschner JM, Wampler Muskardin T, Ghodke-Puranik Y, Purmalek M, Eliopoulos E, Zervou MI, Goulielmos GN, Howard M, Kaplan MJ, Niewold TB. Brief Report: A Novel ELANE Mutation Associated With Inflammatory Arthritis, Defective NETosis, and Recurrent Parvovirus Infection. Arthritis Rheumatol. 2017 Dec; 69 (12):2396-2401 Epub 2017 Nov 08 View PubMed King RL, Paessler ME, Howard MT, Wertheim GB. Incidental EBV-positivity in paediatric post-transplant specimens demonstrates the need for stringent criteria for diagnosing post-transplant lymphoproliferative disorders. J Clin Pathol. 2017 Mar; 70: (3)270-273. View PubMed Scharf EL, Hanson CA, Howard MT, Keegan BM. Serial cerebrospinal fluid examinations to diagnose hematological malignancy causing neurological disease. J Neurooncol. 2016 Aug; 129 (1):77-83 Epub 2016 May 09 View PubMed King RL, Gonsalves WI, Ansell SM, Greipp PT, Frederick LA, Viswanatha DS, He R, Kyle RA, Gertz MA, Kapoor P, Morice WG, Howard MT. Lymphoplasmacytic Lymphoma With a Non-IgM Paraprotein Shows Clinical and Pathologic Heterogeneity and May Harbor MYD88 L265P Mutations. Am J Clin Pathol. 2016 Jun; 145 (6):843-51 Epub 2016 June 21 View PubMed Motosue MS, Howard MT, Butterfield JH. Rituximab in a patient with splenic marginal zone lymphoma and acquired angioedema. Ann Allergy Asthma Immunol 2016 May; 116 (5):472-3 Epub 2016 Mar 24 View PubMed Romano RC, Cohen DN, Howard MT, Wieland CN. A Primary Cutaneous CD30-Positive T-Cell Lymphoproliferative Disorder Arising in a Patient With Multiple Myeloma and Cutaneous Amyloidosis. Am J Dermatopathol. 2016 May; 38 (5):388-92 View PubMed Jabcuga CE, Jin L, Macon WR, Howard MT, Oliveira AM, King RL. Broadening the Morphologic Spectrum of Bartonella henselae Lymphadenitis: Analysis of 100 Molecularly Characterized Cases. Am J Surg Pathol. 2016 Mar; 40: (3)342-7. View PubMed King RL, Howard MT. Lymphocytic variant of hypereosinophilic syndrome mimicking peripheral t-cell lymphoma in a young woman Blood.2016 Jan 14;127:(2):268. Schmelkin LA, Howard MT, Steensma DP, Fleming MD, Rodriguez V, Khan S, Gangat N, Wolanskyj A, Patnaik MM. Clinico-pathological features and outcomes in patients with congenital sideroblastic anemias Blood. 2015 Dec 3; 126(23):3355. Epub 1900 Jan 01. Reichard KK, Chen D, Pardanani A, McClure RF, Howard MT, Kurtin PJ, Wood AJ, Ketterling RP, King RL, He R, Morice WG, Hanson CA. Morphologically occult systemic mastocytosis in bone marrow: clinicopathologic features and an algorithmic approach to diagnosis. Am J Clin Pathol. 2015 Sep; 144(3):493-502. View PubMed He R, Wiktor AE, Hanson CA, Ketterling RP, Kurtin PJ, Van Dyke DL, Litzow MR, Howard MT, Reichard KK. Conventional karyotyping and fluorescence in situ hybridization: an effective utilization strategy in diagnostic adult acute myeloid leukemia. Am J Clin Pathol. 2015 Jun; 143 (6):873-8 View PubMed Rosado FG, Morice WG, He R, Howard MT, Timm M, McPhail ED. Immunophenotypic features by multiparameter flow cytometry can help distinguish low grade B-cell lymphomas with plasmacytic differentiation from plasma cell proliferative disorders with an unrelated clonal B-cell process. Br J Haematol. 2015 May; 169(3):368-76. Epub 2015 Feb 02. View PubMed Mir MA, Kochuparambil ST, Abraham RS, Rodriguez V, Howard M, Hsu AP, Jackson AE, Holland SM, Patnaik MM. Spectrum of myeloid neoplasms and immune deficiency associated with germline GATA2 mutations. Cancer Med. 2015 Apr; 4(4):490-9. Epub 2015 Jan 26. View PubMed Jevremovic D, Timm MM, Reichard KK, Morice WG, Hanson CA, Viswanatha DS, Howard MT, Nguyen PL. Loss of blast heterogeneity in myelodysplastic syndrome and other chronic myeloid neoplasms. Am J Clin Pathol. 2014 Sep; 142(3):292-8. View PubMed Humeniuk MS, Liang JJ, Howard M, Inwards DJ. Spontaneous complete remission of angioimmunoblastic T-cell lymphoma. Proc (Bayl Univ Med Cent). 2014 Jul; 27 (3):242-5 View PubMed Kaufman GP, Larsen JT, Elliott MA, Howard MT. Pancytopenia with focal serous atrophy (gelatinous transformation) of the bone marrow. J Hematopathol. 2014 May; 7(2):91-2. Mir MA, Kochuparambil ST, Abraham RS, Rodriguez V, Howard MT, Hsu AP, Jackson AE, Holland SM, Patnaik MM. Spectrum of myloid neoplasms and immune deficiency associated with germline GATA2 mutations. Cancer Medicine. 2014. He R, Wiktore A, Hanson C, Ketterling R, Kurtin P, Van Dyke D, Litzow M, Howard M, Reichard K. Conventional Karyotyping and Fluorescence In-Situ Hybridization: An Effective Utilizaiton Strategy in Diagnostic Adult Acute Myloid Leukemia. American Journal of Clinical Pathology. 2014. Smeltzer JP, Howard MT, Gonsalves WI, Witzig TE. Epstein-barr virus infection in an elderly nonimmunocompromised adult successfully treated with rituximab. Case Rep Hematol. 2014; 2014:641483 Epub 2014 Feb 10 View PubMed King RL, Howard MT, Bagg A. Hodgkin lymphoma: pathology, pathogenesis, and a plethora of potential prognostic predictors. Adv Anat Pathol. 2014 Jan; 21: (1)12-25. View PubMed Neff JL, Howard MT, Morice WG. Distinguishing T-cell Large Granular Lymphocytic Leukemia from Reactive Conditions: Laboratory Tools and Challenges in Their Use. Surg Pathol Clin. 2013 Dec; 6: (4)631-9. View PubMed King RL, Howard MT, Hodnefield JM, Morice WG. IgM multiple myeloma: pathologic evaluation of a rare entity. Am J Clin Pathol. 2013 Oct; 140(4):519-24. View PubMed Singh S, Howard MT, Papadakis KA. Chronic diarrhea after autologous stem cell transplantation for peripheral T-cell lymphoma. Gastroenterology. 2013 Aug; 145(2):e3-5. Epub 2013 Jun 26. View PubMed Kloesel B, Vaidya R, Howard MT, Thompson CA. A unifying diagnosis for pancytopenia, fever, hypoglycemia, and lactic acidosis. Am J Hematol. 2013 Jan; 88(1):78-81. Epub 2012 Mar 28. View PubMed Howard MT, Hodnefield J, Morice WG. Immunohistochemical phenotyping of plasma cells in lymphoplasmacytic lymphoma/Waldenstrom's macroglobulinemia is comparable to flow cytometric techniques. Clin Lymphoma Myeloma Leuk. 2011 Feb; 11(1):96-8. View PubMed Howard M, Dogan A. Diagnosis of Nodal Peripheral T-Cell Lymphomas. Surg Pathol Clin. 2010 Dec; 3 (4):955-88 Epub 2010 Nov 27 View PubMed Advani AS, Tiu R, Saunthararajah Y, Maciejewski J, Copelan EA, Sobecks R, Sekeres MA, Bates J, Rush ML, Tripp B, Salvado A, Noon E, Howard M, Jin T, Hsi E, Egorin MJ, Lim K, Cotta CV, Price C, Kalaycio M. A Phase 1 study of imatinib mesylate in combination with cytarabine and daunorubicin for c-kit positive relapsed acute myeloid leukemia. Leuk Res. 2010 Dec; 34(12):1622-6. Epub 2010 Apr 27. View PubMed Howard MT, Bejanyan N, Maciejewski JP, Hsi ED. T/NK large granular lymphocyte leukemia and coexisting monoclonal B-cell lymphocytosis-like proliferations. An unrecognized and frequent association. Am J Clin Pathol. 2010 Jun; 133(6):936-41. View PubMed Flanigan KM, Dunn DM, von Niederhausern A, Howard MT, Mendell J, Connolly A, Saunders C, Modrcin A, Dasouki M, Comi GP, Del Bo R, Pickart A, Jacobson R, Finkel R, Medne L, Weiss RB. DMD Trp3X nonsense mutation associated with a founder effect in North American families with mild Becker muscular dystrophy. Neuromuscul Disord. 2009 Nov; 19 (11):743-8 Epub 2009 Sept 29 View PubMed Howard MT, Dufresne S, Swerdlow SH, Cook JR. Follicular lymphoma of the spleen: multiparameter analysis of 16 cases. Am J Clin Pathol. 2009 May; 131(5):656-62. View PubMed PST-20514303 Home Publications