Publications Print Wang Z, VanderPluym JH, Halker Singh RB, Alsibai RA, Roellinger DL, Firwana M, Murad MH. Safety of Triptans in Patients Who Have or Are at High Risk for Cardiovascular Disease: A Target Trial Emulation. Mayo Clin Proc. 2024 Nov; 99 (11):1722-1731 Epub 2024 Aug 30 View PubMed Ailani J, Lalla A, Halker Singh RB, et al. Benefit-Risk Assessment Based on Number Needed to Treat and Number Needed to Harm: Atogepant vs Calcitonin Gene–Related Peptide Monoclonal Antibodies. Cephalalgia (Accepted for publication). 2024. Ailani J, Gandhi P, Lalla A, Halker Singh R, McAllister P, Smith JH, Dabruzzo B, Chalermpalanupap N, Kelton K, Nahas SJ. Cost per treatment responder analysis of atogepant compared to rimegepant for the preventive treatment of episodic migraine. Headache. 2024 Sep 9 Epub 2024 Sept 09 View PubMed Kiarashi J, Halker Singh RB. Diversity, Equity, and Inclusion in Headache Care and Research. Continuum (Minneap Minn). 2024 Apr 1; 30 (2):498-511 View PubMed Charles AC, Digre KB, Goadsby PJ, Robbins MS, Hershey A, American Headache Society. Calcitonin gene-related peptide-targeting therapies are a first-line option for the prevention of migraine: An American Headache Society position statement update. Headache. 2024 Apr; 64 (4):333-341 Epub 2024 Mar 11 View PubMed Tassorelli C, Onishchenko K, Halker Singh RB, Duan M, Dupont-Benjamin L, Hemstock M, Voller C, McAllister P, Nahas SJ, Gandhi P, Ailani J. Comparative efficacy, quality of life, safety, and tolerability of atogepant and rimegepant in migraine prevention: A matching-adjusted indirect comparison analysis. Cephalalgia. 2024 Feb; 44 (2):3331024241235156 View PubMed Friedman DI, Halker Singh RB, Powers SW. The 2023 Scottsdale Headache Symposium. Headache. 2023 Oct; 63 (9):1330-1331 Epub 2023 Oct 05 View PubMed Lipton RB, Halker Singh RB, Mechtler L, McVige J, Ma J, Yu SY, Stokes J, Dabruzzo B, Gandhi P, Ashina M. Patient-reported migraine-specific quality of life, activity impairment and headache impact with once-daily atogepant for preventive treatment of migraine in a randomized, 52-week trial. Cephalalgia. 2023 Aug; 51 (8):3331024231190296 View PubMed Blumenfeld AM, Rabany L, Ironi A, Stark-Inbar A, Harris D, Halker Singh RB, Harriott AM. Temporal analysis of remote electric neuromodulation for the prevention of migraine. Pain Manag. 2023 Aug; 13 (8):425-432 Epub 2023 Aug 24 View PubMed de Boer I, Ambrosini A, Halker Singh RB, Baykan B, Buse DC, Tassorelli C, Jensen RH, Pozo-Rosich P, Terwindt GM, International Headache Society Women's Leadership Forum. Harassment in the headache field: a global web-based cross-sectional survey. Cephalalgia. 2023 Aug; 43 (8):3331024231193099 View PubMed Dodick DW, Blumenfeld AM, Halker Singh RB, Williams R, Zhang F, Chen PW, Hsu CP, Peng C, Snellman J, Chehrenama M, Ailani J. Post hoc analysis of clinical trial data and pharmacokinetic data to assess wearing-off of erenumab within monthly treatment cycle. Headache. 2023 Feb; 63 (2):233-242 Epub 2022 Oct 13 View PubMed Urtecho M, Wagner B, Wang Z, VanderPluym JH, Halker Singh RB, Noyes J, Butler ME, Murad MH. A qualitative evidence synthesis of patient perspectives on migraine treatment features and outcomes. Headache. 2023 Feb; 63 (2):185-201 Epub 2023 Jan 05 View PubMed VanderPluym JH, Mangipudi K, Mbonde AA, Gritsch D, Caronna E, Halker Singh RB, Butterfield RJ, Smith JH. Incidence of Status Migrainosus in Olmsted County, Minnesota, United States: Characterization and Predictors of Recurrence. Neurology. 2023 Jan 17; 100 (3):e255-e263 Epub 2022 Sept 29 View PubMed Urtecho M, Wagner B, Wang Z, VanderPluym J, Halker Singh R, Noyes J. A qualitative evidence synthesis of patient perspectives on migraine treatment features and outcomes The Journal of Head and Face Pain. 2023. de Boer I, Ambrosini A, Halker Singh RB, Baykan B, Buse DC, Tassoreli C, Jensen RH, Pozo-Rosich P, Terwindt GM, International Headache Society Women's Leadership Forum. Perceived barriers to career progression in the headache field: A global web-based cross-sectional survey. Cephalalgia. 2022 Dec; 42 (14):1498-1509 Epub 2022 Sept 07 View PubMed Chhabra N, Grill MF, Singh RBH. Post-COVID Headache: A Literature Review. Curr Pain Headache Rep. 2022 Nov; 26 (11):835-842 Epub 2022 Oct 05 View PubMed Chiang CC, Halker Singh RB. Acute Treatment of Headache (Focus on Migraine). Semin Neurol. 2022 Aug; 42 (4):494-502 Epub 2022 Nov 02 View PubMed Kanegi SL, Zhang N, Armand CE, Halker Singh RB, Robbins MS, Vinokur M, Lee J, Rosen N. Headache fellowship match shareholder insights. Headache. 2022 Jun; 62 (6):766-769 Epub 2022 June 07 View PubMed Lipton RB, Singh RBH, Revicki DA, Zhao S, Shewale AR, Lateiner JE, Dodick DW. Functionality, satisfaction, and global impression of change with ubrogepant for the acute treatment of migraine in triptan insufficient responders: a post hoc analysis of the ACHIEVE I and ACHIEVE II randomized trials. J Headache Pain. 2022 Apr 25; 23 (1):50 View PubMed Arca KN, VanderPluym JH, Halker Singh RB. Narrative review of neuroimaging in migraine with aura. Headache. 2021 Oct; 61 (9):1324-1333 Epub 2021 July 26 View PubMed Ailani J, Lipton RB, Goadsby PJ, Guo H, Miceli R, Severt L, Finnegan M, Trugman JM, ADVANCE Study Group. Atogepant for the Preventive Treatment of Migraine. N Engl J Med. 2021 Aug 19; 385 (8):695-706 View PubMed Arca KN, Halker Singh RB. Dehydration and Headache. Curr Pain Headache Rep. 2021 Jul 15; 25 (8):56 Epub 2021 July 15 View PubMed Burish MJ, Ahmed ZA, Rosen NL, Halker Singh RB. Grand rounds education in neurology, with a focus on headache medicine. Headache. 2021 Jul; 61 (7):1077-1085 Epub 2021 May 15 View PubMed VanderPluym JH, Halker Singh RB, Urtecho M, Morrow AS, Nayfeh T, Torres Roldan VD, Farah MH, Hasan B, Saadi S, Shah S, Abd-Rabu R, Daraz L, Prokop LJ, Murad MH, Wang Z. Acute Treatments for Episodic Migraine in Adults: A Systematic Review and Meta-analysis. JAMA. 2021 Jun 15; 325 (23):2357-2369 View PubMed Chiang CC, Halker Singh R, Lalvani N, Shubin Stein K, Henscheid Lorenz D, Lay C, Dodick DW, Newman LC. Patient experience of telemedicine for headache care during the COVID-19 pandemic: An American Migraine Foundation survey study. Headache. 2021 May; 61 (5):734-739 Epub 2021 May 21 View PubMed Ashina M, Buse DC, Ashina H, Pozo-Rosich P, Peres MFP, Lee MJ, Terwindt GM, Halker Singh R, Tassorelli C, Do TP, Mitsikostas DD, Dodick DW. Migraine: integrated approaches to clinical management and emerging treatments. Lancet. 2021 Apr 17; 397 (10283):1505-1518 Epub 2021 Mar 25 View PubMed O'Brien HL, Halker Singh RB. Breaking down barriers to care: Understanding migraine knowledge gaps among women's healthcare providers. Headache 2021 Jan; 61 (1):7-8 View PubMed Burkett JG, Robbins MS, Robertson CE, Mete M, Saikali NP, Halker Singh RB, Ailani J. Sphenopalatine ganglion block in primary headaches: An American Headache Society member survey. Neurol Clin Pract. 2020 Dec; 10 (6):503-509 View PubMed Lipton RB, Cohen JM, Bibeau K, Galic M, Seminerio MJ, Ramirez Campos V, Halker Singh RB, Ailani J. Reversion From Chronic Migraine to Episodic Migraine in Patients Treated With Fremanezumab: Post Hoc Analysis From HALO CM Study. Headache. 2020 Nov; 60 (10):2444-2453 Epub 2020 Nov 11 View PubMed Arca KN, Smith JH, Chiang CC, Starling AJ, Robertson CE, Halker Singh RB, Schwedt TJ, Kissoon NR, Garza I, Rozen TD, Boes CJ, Whealy MA, VanderPluym JH. COVID-19 and Headache Medicine: A Narrative Review of Non-Steroidal Anti-Inflammatory Drug (NSAID) and Corticosteroid Use. Headache. 2020 Sep; 60 (8):1558-1568 Epub 2020 July 10 View PubMed Robblee J, Buse DC, Halker Singh RB, Schusse CM, Riggins N, Rayhill ML, Loder EW, Donnelly M, Borrero-Mejias C. Ten Eleven Things Not to Say to Healthcare Professionals During the Coronavirus Disease 2019 Pandemic. Headache. 2020 Sep; 60 (8):1837-1845 Epub 2020 Aug 19 View PubMed VanderPluym JH, Halker Singh RB, Farah MH, Viola KE, Hasan B, Saadi S, Shah S, Nayfeh T, Prokop LJ, Murad MH, Wang Z. Acute Treatments for Episodic Migraine: Surveillance Report 2: Literature Update Period: September 2, 2021, Through December 30, 2021 Converted From Scientific Report. 2020 Jul. View PubMed Halker Singh RB, VanderPluym JH, Hasan B, Farah MH, Viola KE, Saadi S, Shah S, Nayfeh T, Prokop LJ, Murad MH, Wang Z. Systematic Review on Acute Treatments for Episodic Migraine: Surveillance Report 1: Literature Update Period: July 2020 through September 2021 Converted From Scientific Report. 2020 Jul. View PubMed VanderPluym JH, Halker Singh RB, Farah MH, Viola KE, Hasan B, Saadi S, Shah S, Nayfeh T, Prokop LJ, Murad MH, Wang Z. Acute Treatments for Episodic Migraine: Surveillance Report 3: Literature Update Period: December 31, 2021, through March 21, 2022 Rockville (MD): Agency for Healthcare Research and Quality (US). 2020 Jul. View PubMed Robblee J, Starling AJ, Halker Singh RB, Riggins N. Teleneurology for Primary Headache Disorders. Pract Neurol. 2020 Jun; 31-39. Szperka CL, Ailani J, Barmherzig R, Klein BC, Minen MT, Halker Singh RB, Shapiro RE. Migraine Care in the Era of COVID-19: Clinical Pearls and Plea to Insurers. Headache. 2020 May; 60 (5):833-842 Epub 2020 Apr 03 View PubMed Dodick DW, Lipton RB, Ailani J, Halker Singh RB, Shewale AR, Zhao S, Trugman JM, Yu SY, Viswanathan HN. Ubrogepant, an Acute Treatment for Migraine, Improved Patient-Reported Functional Disability and Satisfaction in 2 Single-Attack Phase 3 Randomized Trials, ACHIEVE I and II. Headache. 2020 Apr; 60 (4):686-700 Epub 2020 Feb 19 View PubMed Borrero-Mejias C, Starling AJ, Burch R, Loder E, Migraine Mavens Writing Consortium, Migraine Mavens Writing Consortium . Eleven Things Not to Say to Your Female Colleagues. Headache. 2019 Nov; 59 (10):1846-1854 Epub 2019 Sept 26 View PubMed Doty EG, Krege JH, Jin L, Raskin J, Halker Singh RB, Kalidas K. Sustained responses to lasmiditan: Results from post-hoc analyses of two Phase 3 randomized clinical trials for acute treatment of migraine. Cephalalgia. 2019 Oct; 39 (12):1569-1576 Epub 2019 July 03 View PubMed Halker Singh RB, Ailani J, Robbins MS. Neuromodulation for the Acute and Preventive Therapy of Migraine and Cluster Headache. Headache. 2019 Jul; 59 Suppl 2:33-49 View PubMed Halker Singh RB, Starling AJ, VanderPluym J. Migraine acute therapies. Practical Neurology. 2019 May; 63-7. Arca KN, Halker Singh RB. The Hypertensive Headache: a Review. Curr Pain Headache Rep. 2019 Mar 14; 23 (5):30 View PubMed Halker Singh RB, Aycardi E, Bigal ME, Loupe PS, McDonald M, Dodick DW. Sustained reductions in migraine days, moderate-to-severe headache days and days with acute medication use for HFEM and CM patients taking fremanezumab: Post-hoc analyses from phase 2 trials. Cephalalgia. 2019 Jan; 39 (1):52-60 Epub 2018 May 03 View PubMed Schroeder RA, Brandes J, Buse DC, Calhoun A, Eikermann-Haerter K, Golden K, Halker R, Kempner J, Maleki N, Moriarty M, Pavlovic J, Shapiro RE, Starling A, Young WB, Nebel RA. Sex and Gender Differences in Migraine-Evaluating Knowledge Gaps. J Womens Health (Larchmt). 2018 Aug; 27 (8):965-973 View PubMed Grimsrud KW, Halker Singh RB. Emerging Treatments in Episodic Migraine. Curr Pain Headache Rep. 2018 Jul 16; 22 (9):61 Epub 2018 July 16 View PubMed Arca KN, Halker Singh RB. SUNCT and SUNA: an Update and Review. Curr Pain Headache Rep. 2018 Jun 21; 22 (8):56 Epub 2018 June 21 View PubMed Dodick D, Starling AJ, Wethe J, Pang Y, Messner LV, Smith C, Halker RB, Bogle JM, Mandrekar J, Talaber A, Leong D. The effect of the King-Devick reading acceleration program on reading fluency and comprehension: a summary of randomized clinical trials. Vision Development and Rehabilitation.2017 Dec;3:(4):217-28. Dhawan PS, Leong D, Tapsell L, Starling AJ, Galetta SL, Balcer LJ, Overall TL, Adler JS, Halker-Singh RB, Vargas BB, Dodick D. King-Devick Test identifies real-time concussion and asymptomatic concussion in youth athletes. Neurol Clin Pract. 2017 Dec; 7 (6):464-473 View PubMed Matharu M, Halker R, Pozo-Rosich P, DeGryse R, Manack Adams A, Aurora SK. The impact of onabotulinumtoxinA on severe headache days: PREEMPT 56-week pooled analysis. J Headache Pain. 2017 Dec; 18 (1):78 Epub 2017 Aug 01 View PubMed Kingston W, Halker R. LASH: A Review of the Current Literature. Curr Pain Headache Rep. 2017 Aug; 21 (8):36 View PubMed Silberstein S, Winner PK, McAllister PJ, Tepper SJ, Halker R, Mahmoud RA, Siffert J. Early Onset of Efficacy and Consistency of Response Across Multiple Migraine Attacks From the Randomized COMPASS Study: AVP-825 Breath Powered((R)) Exhalation Delivery System (Sumatriptan Nasal Powder) vs Oral Sumatriptan. Headache. 2017 Jun; 57 (6):862-876 Epub 2017 May 11 View PubMed Kingston W, Hoxworth J, Halker-Singh R. Spontaneous intracranial hypotension diagnosed as Chiari I malformation. Neurology. 2017 Mar 28; 88 (13):1294 View PubMed Halker RB, Starling AJ, Vargas BB, Schwedt TJ. ACE and ARB Agents in the Prophylactic Therapy of Migraine-How Effective Are They? Curr Treat Options Neurol. 2016 Apr; 18 (4):15 View PubMed Robbins MS, Robertson CE, Kaplan E, Ailani J, Charleston L 4th, Kuruvilla D, Blumenfeld A, Berliner R, Rosen NL, Duarte R, Vidwan J, Halker RB, Gill N, Ashkenazi A. The Sphenopalatine Ganglion: Anatomy, Pathophysiology, and Therapeutic Targeting in Headache. Headache. 2016 Feb; 56 (2):240-58 Epub 2015 Nov 30 View PubMed Dilli E, Halker R, Vargas B, Hentz J, Radam T, Rogers R, Dodick D. Occipital nerve block for the short-term preventive treatment of migraine: A randomized, double-blinded, placebo-controlled study. Cephalalgia. 2015 Oct; 35 (11):959-68 Epub 2014 Dec 12 View PubMed Steenerson K, Halker R. A Practical Approach to the Diagnosis of Spontaneous Intracranial Hypotension. Curr Pain Headache Rep. 2015 Aug; 19 (8):35 View PubMed Baron EP, Markowitz SY, Lettich A, Hastriter E, Lovell B, Kalidas K, Dodick DW, Schwedt TJ, American Headache Society Headache Fellows Research Consortium. Triptan education and improving knowledge for optimal migraine treatment: an observational study. Headache. 2014 Apr; 54 (4):686-97 Epub 2014 Feb 12 View PubMed Wells RE, Markowitz SY, Baron EP, Hentz JG, Kalidas K, Mathew PG, Halker R, Dodick DW, Schwedt TJ. Identifying the factors underlying discontinuation of triptans. Headache. 2014 Feb; 54(2):278-89. Epub 2013 Sep 03. View PubMed Starling A, Hernandez F, Hoxworth JM, Trentman T, Halker R, Vargas BB, Hastriter E, Dodick D. Sensitivity of MRI of the spine compared with CT myelography in orthostatic headache with CSF leak. Neurology. 2013 Nov 12; 81(20):1789-92. Epub 2013 Oct 09. View PubMed Halker RB, Vargas BB. Primary exertional headache: updates in the literature. Curr Pain Headache Rep. 2013 Jun; 17 (6):337 View PubMed Starling AJ, Hoffman-Snyder C, Halker RB, Wellik KE, Vargas BB, Dodick DW, Demaerschalk BM, Wingerchuk DM. Risk of development of medication overuse headache with nonsteroidal anti-inflammatory drug therapy for migraine: a critically appraised topic. Neurologist. 2011 Sep; 17(5):297-9. View PubMed Halker RB, Hastriter EV, Dodick DW. Chronic daily headache: an evidence-based and systematic approach to a challenging problem. Neurology. 2011 Feb 15; 76(7 Suppl 2):S37-43. View PubMed Halker R, Vargas B, Dodick DW. Cluster headache: diagnosis and treatment. Semin Neurol. 2010 Apr; 30(2):175-85. Epub 2010 Mar 29. View PubMed Halker RB, Barrs DM, Wellik KE, Wingerchuk DM, Demaerschalk BM. Establishing a diagnosis of benign paroxysmal positional vertigo through the dix-hallpike and side-lying maneuvers: a critically appraised topic. Neurologist. 2008 May; 14 (3):201-4 View PubMed Halker RB, Demaerschalk BM, Wellik KE, Wingerchuk DM, Rubin DI, Crum BA, Dodick DW. Caffeine for the prevention and treatment of postdural puncture headache: debunking the myth. Neurologist. 2007 Sep; 13(5):323-7. View PubMed Halker RB, Pierchala LA, Badr MS. Upper airway mechanics and post-hypoxic ventilatory decline during NREM sleep. Sleep Breath. 2007 Sep; 11(3):165-70. View PubMed PST-20226002 Home Publications