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William D. Freeman, M.D.

  1. Neurocritical Care Specialist
  2. Vascular Neurologist
  3. Neurologist
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Publications

  1. Benkirane M, Bonhomme M, Morsy H, Safgren SL, Marelli C, Chaussenot A, Smedley D, Cipriani V, de Sainte-Agathe JM, Ding C, Larrieu L, Vestito L, Margot H, Lesca G, Ramond F, Castrioto A, Baux D, Verheijen J, Sansa E, Giunti P, Haetty A, Bergougnoux A, Pointaux M, Ardouin O, Van Goethem C, Vincent MC, Hadjivassiliou M, Cossee M, Rouaud T, Bartsch O, Freeman WD, Wierenga KJ, Klee EW, Vandrovcova J, Houlden H, Debant A, Koenig M. De novo and inherited monoallelic variants in TUBA4A cause ataxia and spasticity. Brain. 2024 Nov 4; 147 (11):3681-3689
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  2. Freund BE, Barrios ML, Feyissa AM, Sabsevitz D, Grewal SS, Freeman WD, Middlebrooks EH, Sanchez-Garavito JE, Quinones-Hinojosa A, Tatum WO. A review of acute symptomatic seizures during awake craniotomy for tumour resection. Br J Neurosurg. 2024 Oct 16; 1-6 [Epub ahead of print]
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  3. Fottinger F, Sharma R, Salman SD, Weston AD, Erickson BJ, Huynh T, Tawk RG, Freeman WD. The ABCs of Subarachnoid Hemorrhage Blood Volume Measurement: A Simplified Quantitative Method Predicts Outcomes and Delayed Cerebral Ischemia. J Am Heart Assoc. 2024 Oct 15; 13 (20):e032195 Epub 2024 Oct 11
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  4. Harahsheh E, English SW, Demaerschalk BM, Barrett KM, Freeman. Telemedicine-Enabled Ambulances for Prehospital Acute Stroke Management: A Pilot Study Mayo Clinic Proceedings: Digital Health. 2024; 2(4):533-541.
  5. Sakusic A, Rabinstein AA, Anisetti B, Mandrekar J, Wijdicks EFM, Freeman WD, Braksick SA. Timing of Anticoagulation Resumption and Risk of Ischemic and Hemorrhagic Complications in Patients With ICH and Mechanical Heart Valves. Neurology. 2024 Aug 27; 103 (4):e209664 Epub 2024 Aug 05
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  6. Khan M, Lee J, Kramer C, Bojaxhi E, Szymkiewicz E, Rabai F, Peel J, Ng L, Gauthier M, Nimma S, Fox WC, Freeman WD, Rabinstein A, Pingree M, Kissoon N, Reuter P, Dyer A, Pizzi MA, Gatica-Moris S, Lim D, Newman D, Busl KM, Smith CR, Troxel AB, Fava M, Illenberger N, Pop R, Yang W, Frota LM, Gao H, Shan G, Hoh BL, Maciel CB. Rationale and Design for the BLOCK-SAH Study (Pterygopalatine Fossa Block as an Opioid-Sparing Treatment for Acute Headache in Aneurysmal Subarachnoid Hemorrhage): A Phase II, Multicenter, Randomized, Double-Blinded, Placebo-Controlled Clinical Trial with a Sequential Parallel Comparison Design. Neurocrit Care. 2024 Aug 13 [Epub ahead of print]
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  7. Durand NC, Kim HG, Patel VN, Turnbull MT, Siegel JL, Hodge DO, Tawk RG, Meschia JF, Freeman WD, Zubair AC. Mesenchymal Stem Cell Therapy in Acute Intracerebral Hemorrhage: A Dose-Escalation Safety and Tolerability Trial. Neurocrit Care. 2024 Aug; 41 (1):59-69 Epub 2023 Dec 19
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  8. Yi H, Kim H, Kim KR, Kim JH, Kim J, Lee H, Grewal SS, Freeman WD, Yeo WH. Flexible low-profile external ventricular drain catheter for real-time brain monitoring. Biosens Bioelectron. 2024 Jul 1; 255:116267 Epub 2024 Apr 02
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  9. Vazquez-Medina A, Turnbull MT, James CL, Cowart JB, Lesser E, Carter RE, Ross OA, Miller DA, Meschia JF, De Jesus Espinosa A, Weinshilboum R, Freeman WD. Nimodipine-associated standard dose reductions and neurologic outcomes after aneurysmal subarachnoid hemorrhage: the era of pharmacogenomics. Pharmacogenomics J. 2024 Jun 18; 24 (4):19 Epub 2024 June 18
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  10. Moniz-Garcia D, Ravindran K, Wessell A, Muneer MS, Ahmed E, Perez Vega C, Kashyap S, Vibhute P, Gupta V, Freeman WD, Sandhu S, Tawk RG. Intracranial aneurysms in patients with acute ischemic stroke prevalence and influence on mechanical thrombectomy over 14 years in a tertiary-care center. J Clin Neurosci. 2024 Jun; 124:109-114 Epub 2024 May 01
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  11. Greco E, Ghaith AKA, Rios-Zermeno J, Ghanem M, Perez-Vega C, Kashyap S, Freeman WD, Miller DA, Huynh TJ, Bydon M, Middlebrooks EH, Sandhu SJS, Tawk RG. Long-Term Safety and Efficacy of Pipeline Embolization Device in Anterior and Posterior Circulation Aneurysms: A Systematic Review and Meta-Analysis. World Neurosurg. 2024 May; 185:103-112 Epub 2024 Feb 01
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  12. Erben Y, Li Y, Da Rocha-Franco JA, Tawk RG, Barrett KM, Freeman WD, Lin M, Huang JF, Miller D, Farres H, Brott TG, Meschia JF, Hakaim AG. Asymptomatic Females Are at Higher Risk for Perioperative TIA/Stroke and Males Are at Higher Risk for Long-Term Mortality after Carotid Artery Stenting: A Vascular Quality Initiative Analysis. Int J Angiol. 2024 Feb; 33 (1):36-45 Epub 2020 Sept 16
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  13. Moniz-Garcia D, Bojaxhi E, Borah BJ, Dholakia R, Kim H, Sousa-Pinto B, Almeida JP, Mendhi M, Freeman WD, Sherman W, Christel L, Rosenfeld S, Grewal SS, Middlebrooks EH, Sabsevitz D, Gruenbaum BF, Chaichana KL, Quinones-Hinojosa A. Awake Craniotomy Program Implementation. JAMA Netw Open. 2024 Jan 2; 7 (1):e2352917 Epub 2024 Jan 02
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  14. Tsikvadze M, Machado De Villafane B, Rose M, Peacock S, Peel JB, Ng L, Kramer C, Freeman WD. Diffuse Cerebral Edema With Uncal Herniation Leading to Brain Death in Patient With Fulminant Susac syndrome: Rare Complication of Rare Disease. Neurohospitalist. 2024 Jan; 14 (1):87-94 Epub 2023 Aug 23
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  15. Chaichana Kaisorn, Grewal Sanjeet, Middlebrooks Erik, Bojaxhi Elird, Gruenbaum Benjamin, Christel Lynda, Borah Bijan, Dholakia Ruchita, Kim Han, Cavalcante de Almeida, Freeman William, Sherman Wendy, Rosenfeld Steven, Sabsevitz David, Quinones-Hinojosa Alfredo. Awake Craniotomy Program Implementation: a Cost-Utility Analysis JAMA. 2023.
  16. Perez-Vega C, Sanghavi DK, Moreno Franco P, Chadha RM, Ardon AE, Bojaxhi E, Torp KD, Marshall LA, Halstead TM, Ford VE, Christel LM, Grewal SS, Chaichana KL, Quinones-Hinojosa A, Howard LW, Fox WC, Freeman WD, NPCU Group. Safety and Feasibility of a Fast-Track Pathway for Neurosurgical Craniotomy Patients: Bypassing the Intensive Care Unit. Mayo Clin Proc Innov Qual Outcomes. 2023 Dec; 7 (6):534-543 Epub 2023 Nov 15
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  17. Salman S, Gu Q, Sharma R, Wei Y, Dherin B, Reddy S, Tawk R, Freeman WD. Artificial intelligence and machine learning in aneurysmal subarachnoid hemorrhage: Future promises, perils, and practicalities. J Neurol Sci. 2023 Nov 15; 454:120832 Epub 2023 Oct 10
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  18. Chhabra N, Crepeau AZ, Demaerschalk BM, Knox MG, Freeman WD, Valencia Sanchez C, Marks LA, O'Carroll CB. Does Initiation of Prophylactic Antiseizure Medication Improve Neurological Outcomes in Patients With Acute Intracerebral Hemorrhage?: A Critically Appraised Topic. Neurologist. 2023 Nov 1; 28 (6):422-425 Epub 2023 Nov 01
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  19. Diaz Milian R, Moreno Franco P, Freeman WD, Halamka JD. Revolution or Peril? The Controversial Role of Large Language Models in Medical Manuscript Writing. Mayo Clin Proc. 2023 Oct; 98 (10):1444-1448
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  20. Tsikvadze M, Machado B, Rose M, Peacock S, Peel JB, Ng L, Kramer C, Freeman WD. Diffuse cerebral edema with uncal herniation leading to brain death in patient with fulminant Susac syndrome: Rare complication of rare disease The Neurohospitalist. 2023.
  21. Sakusic A, Chen B, McPhearson K, Badi M, Freeman WD, Huang JF, Siegel JL, Jentoft ME, Oring JM, Verdecia J, Meschia JF. Balamuthia mandrillaris Encephalitis Presenting as a Symptomatic Focal Hypodensity in an Immunocompromised Patient. Open Forum Infect Dis. 2023 Mar; 10 (3):ofad094 Epub 2023 Feb 21
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  22. Zahra K, Domingo RA, Turnbull MT, Santos CD, Peacock SH, Jackson DA, Tawk RG, Siegel JL, Freeman WD. Safety and Tolerability of Concentrated Intraventricular Nicardipine for Poor-Grade Aneurysmal Subarachnoid Hemorrhage-Related Vasospasm. J Pers Med. 2023 Feb 27; 13 (3)
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  23. Bamimore MA, Lee SJ, Perez Vega C, Brown N, Gendreau JL, Al Shaikh RH, Jeevaratnam S, Freeman WD. Management of Poor-Grade Aneurysmal Subarachnoid Hemorrhage and Key Pearls for Achieving Favorable Outcomes: An Illustrative Case. Cureus. 2023 Jan; 15 (1):e33217 Epub 2023 Jan 01
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  24. Sharma R, Tsikvadze M, Peel J, Howard L, Kapoor N, Freeman WD. Multimodal monitoring: practical recommendations (dos and don'ts) in challenging situations and uncertainty. Front Neurol. 2023; 14:1135406 Epub 2023 May 03
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  25. Perez-Vega C, Domingo RA, Tripathi S, Ramos-Fresnedo A, Martinez Santos JL, Rahme RJ, Freeman WD, Sandhu SS, Miller DA, Bendok BR, Brinjikji W, Quinones-Hinojosa A, Meyer FB, Tawk RG, Fox WC. Intracranial Aneurysms in Loeys-Dietz Syndrome: A Multicenter Propensity-Matched Analysis. Neurosurgery. 2022 Oct 1; 91 (4):541-546 Epub 2022 July 14
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  26. English SW, Barrett KM, Freeman WD, Demaerschalk BM, Dumitrascu OM. Improving the Telemedicine Evaluation of Patients With Acute Vision Loss: A Call to Eyes. Neurology. 2022 Aug 30; 99 (9):381-386 Epub 2022 June 28
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  27. Camargo C, Abode-Iyamah K, Shah JS, Bechtle PS, Freeman WD. Comprehensive Perioperative Approach to Complex Spine Deformity Management. Clin Spine Surg. 2022 Aug 1; 35 (7):310-318 Epub 2021 Aug 02
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  28. Bosel J, Niesen WD, Salih F, Morris NA, Ragland JT, Gough B, Schneider H, Neumann JO, Hwang DY, Kantamneni P, James ML, Freeman WD, Rajajee V, Rao CV, Nair D, Benner L, Meis J, Klose C, Kieser M, Suarez JI, Schonenberger S, Seder DB, SETPOINT2 and the IGNITE Study Groups. Effect of Early vs Standard Approach to Tracheostomy on Functional Outcome at 6 Months Among Patients With Severe Stroke Receiving Mechanical Ventilation: The SETPOINT2 Randomized Clinical Trial. JAMA. 2022 May 17; 327 (19):1899-1909
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  29. Muneer MS, Todnem N, Gopal N, Marenco-Hillembrand L, Barakat E, Mbabuike N, Brown BL, Miller DA, Freeman WD, Gupta V, Tawk RG. Pattern of changes in cross sectional area of arterial branches after jailing with pipeline embolization device: beyond parent neck artery patency. Clin Imaging. 2022 Mar; 83:159-165 Epub 2022 Jan 10
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  30. Landolfo KP, Freeman WD. Commentary: It's all in your head. J Thorac Cardiovasc Surg 2022 Mar; 163 (3):978-979 Epub 2020 June 30
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  31. Freeman WD, Libertin CR, Gupta Y, Kempaiah P. Emerging Technologies in Personalized Medicine Molecular Aspects of Medicine. 2022. Epub 2030 Feb 04.
  32. Pratt KA, Peacock SH, Yost KD, Freeman WD, Collins CI, McLaughlin DC. Zero-Calibrating External Ventricular Drains: Exploring Practice. J Neurosci Nurs. 2022 Feb 1; 54 (1):2-5
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  33. Freeman WD, Rogers A, Rabinstein A. TeleNeuroICU: Expanding the Reach of Subspecialty Neurocritical Care. Semin Neurol. 2022 Feb; 42 (1):18-30 Epub 2022 Jan 24
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  34. Poblete RA, Arenas M, Sanossian N, Hong YK, Freeman WD, Lyden PD, Louie SG. Pro-resolving lipid mediators in traumatic brain injury: emerging concepts and translational approach. Am J Transl Res. 2022; 14 (3):1482-1494 Epub 2022 Mar 15
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  35. English SW, Barrett KM, Freeman WD, Demaerschalk BM, Dumitrascu OM. Improving the telemedicine evaluation of patients with acute vision loss. Neurology. 2022; 99 (9):381-6
  36. Domingo RA, Perez-Vega C, Tripathi S, Santos JM, Ramos-Fresnedo A, Erben YM, Freeman WD, Sandhu SS, Huynh T, Williams L, Bendok BR, Brinjikji W, Tawk RG, Fox WC. Intracranial Aneurysms in Patients with Marfan Syndrome: A Multicenter Propensity-Matched Analysis. World Neurosurg. 2021 Nov; 155:e345-e352 Epub 2021 Aug 21
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  37. English SW, Barrett KM, Freeman WD, Demaerschalk BM. Telemedicine-enabled ambulances and mobile stroke units for prehospital stroke management. J Telemed Telecare. 2021 Oct 12; 1357633X211047744 [Epub ahead of print]
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  38. Cheshire WP, Barrett KM, Eidelman BH, Mauricio EA, Huang JF, Freeman WD, Robinson MT, Salomon GR, Ball CT, Gamble DM, Melton VS, Meschia JF. Patient perception of physician empathy in stroke telemedicine. J Telemed Telecare. 2021 Oct; 27 (9):572-581 Epub 2020 Jan 27
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  39. Shaikh RHA, Akinduro OO, Hasan TF, Lee SJ, Ayala E, Quinones-Hinojosa AE, Cushenbery KA, Hammack JE, Yoon JW, Dickson DW, Freeman WD. Hematologic Emergencies in the Postoperative Neurointensive Care Unit Setting: Illustrative Case Series and Differential Diagnosis. J Stroke Cerebrovasc Dis. 2021 Oct; 30(10):106019. Epub 2021 Aug 03.
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  40. Camargo C, Narula T, Jackson DA, Padro T, Freeman WD. Colistin neurotoxicity mimicking Guillain-Barre syndrome in a patient with cystic fibrosis: case report and review. Oxf Med Case Reports. 2021 Sep; 2021 (9):omab080 Epub 2021 Sept 13
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  41. Rose MQ, Santos CD, Rubin DI, Siegel JL, Freeman WD. Guillain-Barre Syndrome After Acute Hepatitis E Infection: A Case Report and Literature Review. Crit Care Nurse. 2021 Aug 1; 41 (4):47-53
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  42. ReFaey K, Freeman WD, Tripathi S, Guerrero-Cazares H, Eatz TA, Meschia JF, Carter RE, Petrucelli L, Meyer FB, Quinones-Hinojosa A. NIH funding trends for neurosurgeon-scientists from 1993-2017: Biomedical workforce implications for neurooncology. J Neurooncol. 2021 Aug; 154 (1):51-62 Epub 2021 July 07
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  43. Tawk RG, Hasan TF, D'Souza CE, Peel JB, Freeman WD. Diagnosis and Treatment of Unruptured Intracranial Aneurysms and Aneurysmal Subarachnoid Hemorrhage. Mayo Clin Proc. 2021 Jul; 96 (7):1970-2000 Epub 2021 May 13
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  44. O'Carroll CB, Brown BL, Freeman WD. Intracerebral Hemorrhage: A Common yet Disproportionately Deadly Stroke Subtype. Mayo Clin Proc. 2021 Jun; 96 (6):1639-1654 Epub 2021 May 02
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  45. Heemskerk JL, Domingo RA, Tawk RG, Vivas-Buitrago TG, Huang JF, Rogers A, Quinones-Hinojosa A, Abode-Iyamah K, Freeman WD. Time Is Brain: Prehospital Emergency Medical Services Response Times for Suspected Stroke and Effects of Prehospital Interventions. Mayo Clin Proc. 2021 Jun; 96 (6):1446-1457 Epub 2021 Mar 10
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  46. Coban MA, Morrison J, Maharjan S, Hernandez Medina DH, Li W, Zhang YS, Freeman WD, Radisky ES, Le Roch KG, Weisend CM, Ebihara H, Caulfield TR. Attacking COVID-19 Progression Using Multi-Drug Therapy for Synergetic Target Engagement. Biomolecules. 2021 May 23; 11 (6)
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  47. Hopkins C, Onweni C, Zambito V, Fairweather D, McCormick K, Ebihara H, Caulfield T, Zhang YS, Freeman WD. Platforms for Personalized Polytherapeutics Discovery in COVID-19. J Mol Biol. 2021 May 14; 433 (10):166945 Epub 2021 Mar 20
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  48. Mehner C, Krishnan S, Chou J, Freeman ML, Freeman WD, Patel T, Turnbull MT. Real versus simulated galactic cosmic radiation for investigating cancer risk in the hematopoietic system - are we comparing apples to apples? Life Sci Space Res (Amst). 2021 May; 29:8-14 Epub 2021 Jan 16
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  49. Erben Y, Franco-Mesa C, Miller D, Lanzino G, Bendok BR, Li Y, Sandhu SJS, Barrett KM, Freeman WD, Lin M, Huang JF, Huynh T, Farres H, Brott TG, Hakaim AG, Brigham TJ, Todnem ND, Tawk RG, Meschia JF. Higher Risk for Reintervention in Patients after Stenting for Radiation-Induced Internal Carotid Artery Stenosis: A Single-Center Analysis and Systematic Review. Ann Vasc Surg. 2021 May; 73:1-14 Epub 2020 Dec 26
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  50. Hopkins C, Onweni C, Zambito V, Fairweather D, McCormick K, Hideki E, Caulfield T, Zhang TS, Freeman WD. Personalized polytherapy approaches to treat COVID-19 Journal of Molecular Biology. 2021.
  51. Onweni CL, Venegas-Borsellino CP, Treece J, Turnbull MT, Ritchie C, Freeman WD. The Power of Mobile Health: The Girl With the Gadgets in Uganda. Mayo Clin Proc Innov Qual Outcomes. 2021 Apr; 5(2):486-494. Epub 2021 Apr 23.
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  52. Ramakrishna JM, Libertin CR, Siegel J, Binnicker MJ, Harris D, Matcha GV, Caulfield T, Freeman WD. Three-tier stratification for CNS COVID-19 to help decide which patients should undergo lumbar puncture with CSF analysis: a case report and literature review. Rom J Intern Med. 2021 Mar 1; 59 (1):88-92 Epub 2021 Mar 05
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  53. Santos CD, Grek AA, Ojard MM, Propst JA, Hastings JJ, Krider TL, Villar DC, Sanghavi DK, Freeman WD, Siegel JL. C19TM: A nurse practitioner and physician assistant-led telemonitoring initiative ensures timely transfer of critically ill coronavirus disease 2019 patients. J Am Assoc Nurse Pract. 2021 Feb 4; 33 (12):1120-1124 Epub 2021 Feb 04
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  54. Freeman WD, Sanghavi DK, Sarab MS, Kindred MS, Dieck EM, Brown SM, Szambelan T, Doty J, Ball B, Felix HM, Dove JC, Mallea JM, Soares C, Simon LV. Robotics in Simulated COVID-19 Patient Room for Health Care Worker Effector Tasks: Preliminary, Feasibility Experiments. Mayo Clin Proc Innov Qual Outcomes. 2021 Feb; 5 (1):161-170 Epub 2020 Dec 14
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  55. Bansal V, Smischney NJ, Kashyap R, Li Z, Marquez A, Diedrich DA, Siegel JL, Sen A, Tomlinson AD, Venegas-Borsellino CP, Freeman WD. Reintubation Summation Calculation: A Predictive Score for Extubation Failure in Critically Ill Patients. Front Med (Lausanne). 2021; 8:789440. Epub 2022 Feb 17.
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  56. Freeman WD, Carlen PL. Cortical Spreading Depolarizations: Under-Recognized Pathophysiology in Brain Disorders. Can J Neurol Sci 2021 Jan; 48 (1):7-8 Epub 2020 Aug 20
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  57. De Biase G, Freeman WD, Bydon M, Smith N, Jerreld D, Pascual J, Casler J, Hasse C, Quinones-Hinojosa A, Abode-Iyamah K. Telemedicine Utilization in Neurosurgery During the COVID-19 Pandemic: A Glimpse Into the Future? Mayo Clin Proc Innov Qual Outcomes. 2020 Dec; 4 (6):736-744 Epub 2020 Dec 10
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  58. Erben Y, Da Rocha-Franco JA, Ball CT, Barrett KM, Freeman WD, Lin M, Tawk R, Huang JF, Vibhute P, Oderich G, Miller DA, Farres H, Davila V, Money SR, Meltzer AJ, Hakaim AG, Brott TG, Meschia JF. Prevalence of Intracranial Aneurysms in Patients with Infrarenal Abdominal Aortic Aneurysms: A Multicenter Experience. Int J Angiol. 2020 Dec; 29 (4):229-236 Epub 2020 June 27
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  59. Pizzi M, Peel JB, Siegel JL, Rogers AN, Onweni CL, Freeman WD. Intracranial Pressure, More Than a Number? Crit Care Med 2020 Dec; 48 (12):e1365-e1366
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  60. Prudencio M, Garcia-Moreno H, Jansen-West KR, Al-Shaikh RH, Gendron TF, Heckman MG, Spiegel MR, Carlomagno Y, Daughrity LM, Song Y, Dunmore JA, Byron N, Oskarsson B, Nicholson KA, Staff NP, Gorcenco S, Puschmann A, Lemos J, Januário C, LeDoux MS, Friedman JH, Polke J, Labrum R, Shakkottai V, McLoughlin HS, Paulson HL, Konno T, Onodera O, Ikeuchi T, Tada M, Kakita A, Fryer JD, Karremo C, Gomes I, Caviness JN, Pittelkow MR, Aasly J, Pfeiffer RF, Veerappan V, Eggenberger ER, Freeman WD, Huang JF, Uitti RJ, Wierenga KJ, Marin Collazo IV, Tipton PW, van Gerpen JA, van Blitterswijk M, Bu G, Wszolek ZK, Giunti P, Petrucelli L. Toward allele-specific targeting therapy and pharmacodynamic marker for spinocerebellar ataxia type 3. Sci Transl Med. 2020 Oct 21; 12(566).
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  61. Felix HM, Rosenbush KA, Lannen AM, Pooley RA, Siegel JL, Brown BL, McMullan ML, Collins CI, Freeman WD. Creation of an optic nerve sheath diameter ultrasound model for NeuroICU education. Mil Med Res. 2020 Sep 21; 7 (1):43 Epub 2020 Sept 21
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  62. Zahra K, Turnbull MT, Zubair AC, Siegel JL, Venegas-Borsellino CP, Tawk RG, Freeman WD. A Combined Approach to Intracerebral Hemorrhage: Intravenous Mesenchymal Stem Cell Therapy with Minimally Invasive Hematoma Evacuation. J Stroke Cerebrovasc Dis. 2020 Aug; 29(8):104931. Epub 2020 May 30.
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  63. Al Shaikh RH, Hasan TF, Becker TL, Ng Tucker LK, Meschia JF, Tawk RG, Ayala E, Freeman WD. Rapidly Resolving and Recurrent Contralateral Subdural Hematoma From Disseminated Intravascular Coagulation. J Stroke Cerebrovasc Dis. 2020 Aug; 29 (8):104872 Epub 2020 May 18
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  64. Tipton PW, D'Souza CE, Greenway MRF, Peel JB, Barrett KM, Eidelman BH, Meschia JF, Mauricio EA, Hattery WM, Siegel JL, Huang JF, TerKonda SP, Demaerschalk BM, Freeman WD. Incorporation of Telestroke into Neurology Residency Training: "Time Is Brain and Education". Telemed J E Health. 2020 Aug; 26 (8):1035-1042 Epub 2019 Dec 10
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  65. Onweni CL, Zhang YS, Caulfield T, Hopkins CE, Fairweather L, Freeman WD. ACEI/ARB therapy in COVID-19: the double-edged sword of ACE2 and SARS-CoV-2 viral docking. Crit Care 2020 Jul 31; 24 (1):475 Epub 2020 July 31
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  66. Erben Y, Li Y, Da Rocha-Franco JA, Tawk RG, Barrett KM, Freeman WD, Lin M, Miller D, Beck AW, Scali ST, Farres H, Brott TG, Meschia JF, Hakaim AG. Higher Long-Term Mortality with Carotid Artery Stenting in Asymptomatic Male Compared with Female Patients in the Southeastern Vascular Study Group. Ann Vasc Surg. 2020 Jul; 66:390-399 Epub 2020 Feb 03
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  67. Clifton WE, Damon AC, Freeman WD. Development of a Lumbar Drain Simulator for Instructional Technique and Skill Assessment. Neurocrit Care. 2020 Jun; 32 (3):894-898
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  68. Collins CI, Hasan TF, Mooney LH, Talbot JL, Fouraker AL, Nelson KF, Ohanian M, Bonnett SL, Tawk RG, Nordan LM, Hodge DO, Kaplan RS, Thiemann BL, Karney M, Freeman WD. Subarachnoid Hemorrhage "Fast Track": A Health Economics and Health Care Redesign Approach for Early Selected Hospital Discharge. Mayo Clin Proc Innov Qual Outcomes. 2020 Jun; 4 (3):238-248 Epub 2020 June 05
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  69. Borsato GS, Siegel JL, Rose MQ, Ojard M, Feyissa AM, Quinones-Hinojosa A, Jackson DA, Rogers ER, Freeman WD. Ketamine in seizure management and future pharmacogenomic considerations. Pharmacogenomics J. 2020 Jun; 20 (3):351-354 Epub 2019 Nov 27
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  70. Erben Y, Barrett KM, Freeman WD, Lin M, Tawk R, Ball CT, Melton VS, Thuro LM, Hakaim AG, Brott TG, Meschia JF. Prevalence of Previously Undiagnosed Abdominal Aortic Aneurysms in Patients with Intracranial Aneurysms: From the Brain and Aortic Aneurysms Study (BAAS). Neurocrit Care. 2020 Jun; 32 (3):796-803
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  71. Akinduro OO, Vivas-Buitrago TG, Haranhalli N, Ganaha S, Mbabuike N, Turnbull MT, Tawk RG, Freeman WD. Predictors of Ventriculoperitoneal shunting following Subarachnoid Hemorrhage treated with External Ventricular Drainage. Neurocrit Care. 2020 Jun; 32 (3):755-764
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  72. Santos CD, Matos NL, Asleh R, Dawit S, Rabinstein AA, O'Carroll CB, Li Z, Freeman WD. The Dilemma of Resuming Antithrombotic Therapy After Intracranial Hemorrhage in Patients With Left Ventricular Assist Devices. Neurocrit Care. 2020 Jun; 32 (3):822-827
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  73. Peacock SH, Grek AA, Rogers ER, Freeman WD, White LJ, Li Z, Hartjes T, Naessens JM. Neuro R(2) score: Predicting high-risk neurologic readmissions within 30 days. Neurology. 2020 Apr 14; 94 (15):e1614-e1621 Epub 2020 Mar 13
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  74. Zahra K, Goldstein ED, Bohnen AM, Freeman WD. "Pseudo CNS Sarcoidosis": Histoplasmosis of Brain Mimicking Steroid Refractory Sarcoidosis. Neurohospitalist. 2020 Apr; 10 (2):150-152 Epub 2019 Nov 11
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  75. James CL, Turnbull MT, Freeman WD. Nimodipine-induced junctional bradycardia in an elderly patient with subarachnoid hemorrhage. Pharmacogenomics. 2020 Apr; 21 (6):387-392 Epub 2020 Apr 14
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  76. Rose MQ, Freeman WD, Santos CD, Rubin DI, Siegel JL. Guillain-Barré Syndrome after an Acute Hepatitis E Infection: A Case Report and Literature Review of Emerging Entity. ACCEPTED PENDING REVISIONS. Critical Care Nurse. 2020.
  77. Jamali SA, Turnbull MT, Kanekiyo T, Vishnu P, Zubair AC, Raper CC, Tawk RG, Freeman WD. Elevated Neutrophil-Lymphocyte Ratio is Predictive of Poor Outcomes Following Aneurysmal Subarachnoid Hemorrhage. J Stroke Cerebrovasc Dis. 2020 Apr; 29 (4):104631 Epub 2020 Jan 18
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  78. Stewart MW, Hasan SA, Collins C, Stanko C, Summer J, Brazis PW, Tawk R, Freeman WD. Can Baseline Computed Tomography Scans Be Used to Identify Patients at High Risk of Vision Loss due to Terson Syndrome? Am J Ophthalmol. 2020 Mar; 211:217-228 Epub 2019 Sept 25
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  79. Porter AL, Ebot J, Lane K, Mooney LH, Lannen AM, Richie EM, Dlugash R, Mayo S, Brott TG, Ziai W, Freeman WD, Hanley DF. Enhancing the Informed Consent Process Using Shared Decision Making and Consent Refusal Data from the CLEAR III Trial. Neurocrit Care. 2020 Feb; 32 (1):340-347
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  80. Haranhalli N, Mbabuike N, Grewal SS, Hasan TF, Heckman MG, Freeman WD, Gupta V, Vibhute P, Brown BL, Miller DA, Jahromi BS, Tawk RG. Topographic correlation of infarct area on CT perfusion with functional outcome in acute ischemic stroke. J Neurosurg. 2020 Jan 1; 132 (1):33-41 Epub 2019 Jan 11
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  81. Turnbull MT, Siegel JL, Becker TL, Stephens AJ, Lopez-Chiriboga AS, Freeman WD. Early Bortezomib Therapy for Refractory Anti-NMDA Receptor Encephalitis. Front Neurol. 2020; 11:188 Epub 2020 Mar 27
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  82. Marenco-Hillembrand L, Suarez-Meade P, Ruiz Garcia H, Murguia-Fuentes R, Middlebrooks EH, Kangas L, Freeman WD, Chaichana KL. Minimally invasive surgery and transsulcal parafascicular approach in the evacuation of intracerebral haemorrhage. Stroke Vasc Neurol. 2020; 5 (1):40-49 Epub 2019 Sept 26
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  83. Rogers A, Ramakrishna JM, Libertin CR, Freeman WD. Value of Broad Range 16S Ribosomal RNA Gene PCR / Sequencing (Br-PCR) of CSF in the Diagnosis of Bacterial Meningitis. IDCases. 2020; 21:e00826 Epub 2020 May 16
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  84. Peacock S, Peel JB, Farres H, Miller D, Ng L, Freeman WD. Vasovagal-Mediated Emergency From a Left Internal Carotid Aneurysm. Neurohospitalist. 2020 Jan; 10 (1):69-70 Epub 2019 Apr 07
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  85. Dhakal LP, Turnbull MT, Jackson DA, Edwards E, Hodge DO, Thottempudi N, Kamireddi P, Akinduro OO, Miller DA, Meschia JF, Freeman WD. Safety, Tolerability, and Efficacy of Pain Reduction by Gabapentin for Acute Headache and Meningismus After Aneurysmal Subarachnoid Hemorrhage: A Pilot Study. Front Neurol. 2020; 11:744 Epub 2020 July 28
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  86. Lara-Velazquez M, Alkharboosh R, Norton ES, Ramirez-Loera C, Freeman WD, Guerrero-Cazares H, Forte AJ, Quinones-Hinojosa A, Sarabia-Estrada R. Chitosan-Based Non-viral Gene and Drug Delivery Systems for Brain Cancer. Front Neurol. 2020; 11:740 Epub 2020 July 30
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  87. Hasan TF, Turnbull MT, Vatz KA, Robinson MT, Mauricio EA, Freeman WD. Burnout and attrition: Expanding the gender gap in neurology? Neurology. 2019 Dec 3; 93 (23):1002-1008 Epub 2019 Nov 05
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  88. Mauricio EA, Freeman WD. Good Night, Geese. J Gen Intern Med. 2019 Nov; 34 (11):2681
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  89. Clifton W, Dove C, Damon A, Freeman WD, Brown B. 3-Dimensional Simulation Videography for Instructional Placement of Bedside External Ventricular Drains. World Neurosurg. 2019 Nov; 131:242 Epub 2019 July 11
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  90. Zahra K, Gopal N, Freeman WD, Turnbull MT. Using Cerebral Metabolites to Guide Precision Medicine for Subarachnoid Hemorrhage: Lactate and Pyruvate. Metabolites. 2019 Oct 23; 9 (11)
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  91. Peacock SH, James C, Turnbull MT, Cowart JB, Reid JM, Freeman WD. Pharmacogenomics of Cytochrome P450 of Nimodipine Metabolism After Aneurysmal Subarachnoid Hemorrhage. J Neurosci Nurs. 2019 Oct; 51 (5):238-242
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  92. Soares C, Clifton W, Freeman WD. Use of Handheld Video Otoscopy for the Diagnosis of Acute Otitis Media: Technical Note. Cureus. 2019 Sep 1; 11 (9):e5547 Epub 2019 Sept 01
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  93. Ziai WC, Thompson CB, Mayo S, McBee N, Freeman WD, Dlugash R, Ullman N, Hao Y, Lane K, Awad I, Hanley DF, Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage (CLEAR III) Investigators. Intracranial Hypertension and Cerebral Perfusion Pressure Insults in Adult Hypertensive Intraventricular Hemorrhage: Occurrence and Associations With Outcome. Crit Care Med. 2019 Aug; 47 (8):1125-1134
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  94. Freeman WD, Karney M. Challenges of Personal Health Records. JAMA 2019 Jun 18; 321 (23):2369
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  95. Blackburn PR, Lin WL, Miller DA, Lorenzo-Betancor O, Edwards ES, Zimmermann MT, Farrugia LP, Freeman WD, Soto AI, Walton RL, Klee EW, Atwal PS, Abraham RS, Billadeau DD, Ross OA, Dickson DW, Meschia JF. X-Linked Lymphoproliferative Syndrome Presenting as Adult-Onset Multi-Infarct Dementia. J Neuropathol Exp Neurol. 2019 May 1; 78 (5):460-466
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  96. Peacock SH, Peel JB, Farres H, Miller DA, Ng LK, Freeman WD. Vasovagal-Mediated Emergency From a Left Internal Carotid Aneurysm The Neurohospitalist. 2019.
  97. Huang P, Freeman WD, Edenfield BH, Brott TG, Meschia JF, Zubair AC. Safety and Efficacy of Intraventricular Delivery of Bone Marrow-Derived Mesenchymal Stem Cells in Hemorrhagic Stroke Model. Sci Rep. 2019 Apr 5; 9 (1):5674 Epub 2019 Apr 05
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  98. McLaughlin DC, Chaichana KL, Freeman WD. Angel Wing Pneumocephalus Sign Following Transsphenoidal Surgery. Neurohospitalist. 2019 Apr; 9 (2):116-117 Epub 2018 July 05
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  99. Freeman WD, Ziai WC, Hanley D. Ventriculostomy-Associated Infection (VAI): In Search of a Definition. Neurocrit Care 2019 Feb; 30 (1):224-225
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  100. Peacock S, Siegel J, Harmer E, Alejos D, Freeman WD. Evaluation of Hospital-wide Readmission Risk Calculator to Predict 30-Day Readmission in Neurocritical Care Patients. J Neurosci Nurs. 2019 Feb; 51 (1):16-19
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  101. Pizzi MA, Alejos D, Hasan TF, Atwal PS, Krishnaiengar SR, Freeman WD. Adult Presentation of Ornithine Transcarbamylase Deficiency: 2 Illustrative Cases of Phenotypic Variability and Literature Review. Neurohospitalist. 2019 Jan; 9 (1):30-36 Epub 2018 Mar 26
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  102. Ebot J, Freeman WD, Wharen R, Diaz MA, Libertin C. MRSA Spinal Epidural Abscess as a Neurosurgical and Infectious Disease Emergency with Unresolved Antimicrobial Solution. Case Rep Infect Dis. 2019; 2019:7413089 Epub 2019 Jan 30
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  103. Turnbull MT, Zubair AC, Meschia JF, Freeman WD. Mesenchymal stem cells for hemorrhagic stroke: status of preclinical and clinical research. NPJ Regen Med. 2019; 4:10 Epub 2019 May 13
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  104. Lorenzo-Betancor O, Blackburn PR, Edwards E, Vazquez-do-Campo R, Klee EW, Labbe C, Hodges K, Glover P, Sigafoos AN, Soto AI, Walton RL, Doxsey S, Bober MB, Jennings S, Clark KJ, Asmann Y, Miller D, Freeman WD, Meschia J, Ross OA. PCNT point mutations and familial intracranial aneurysms. Neurology. 2018 Dec 4; 91 (23):e2170-e2181 Epub 2018 Nov 09
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  105. Hasan TF, Duarte W, Akinduro OO, Goldstein ED, Hurst R, Haranhalli N, Miller DA, Wharen RE Jr, Tawk RG, Freeman WD. Nonaneurysmal "Pseudo-Subarachnoid Hemorrhage" Computed Tomography Patterns: Challenges in an Acute Decision-Making Heuristics. J Stroke Cerebrovasc Dis. 2018 Sep; 27 (9):2319-2326 Epub 2018 June 05
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  106. Muller A, Mould WA, Freeman WD, McBee N, Lane K, Dlugash R, Thompson R, Nekoovaght-Tak S, Madan V, Ali H, Stadnik A, Awad I, Hanley D, Ziai WC, CLEAR investigators. The Incidence of Catheter Tract Hemorrhage and Catheter Placement Accuracy in the CLEAR III Trial. Neurocrit Care. 2018 Aug; 29 (1):23-32
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  107. McLaughlin DC, Hartjes TM, Freeman WD. Sleep Deprivation in Neurointensive Care Unit Patients From Serial Neurological Checks: How Much Is Too Much? J Neurosci Nurs. 2018 Aug; 50 (4):205-210
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  108. Yoon JW, Chen RE, Kim EJ, Akinduro OO, Kerezoudis P, Han PK, Si P, Freeman WD, Diaz RJ, Komotar RJ, Pirris SM, Brown BL, Bydon M, Wang MY, Wharen RE Jr, Quinones-Hinojosa A. Augmented reality for the surgeon: Systematic review. Int J Med Robot. 2018 Aug; 14 (4):e1914 Epub 2018 Apr 30
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  109. Goldstein ED, Schnusenberg L, Mooney L, Raper CC, McDaniel S, Thorpe DA, Franke MT, Anderson LK, McClure LL, Oglesby MM, Lewis CY, Velichko C, Bradley BG, Horn WW Jr, Reid AN, Siegel JL, Cannistraro R, Bechtle P, Barbosa MT, Silvers SM, Brown BL, Freeman WD, Miller DA, Barrett KM, Huang JF. Reducing Door-to-Reperfusion Time for Mechanical Thrombectomy With a Multitiered Notification System for Acute Ischemic Stroke. Mayo Clin Proc Innov Qual Outcomes. 2018 Jun; 2 (2):119-128 Epub 2018 May 24
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  110. Searcy S, Akinduro OO, Spector A, Yoon JW, Brown BL, Freeman WD. Heart-Shaped Bilateral Medullary Pyramidal Infarction as a Pathognomonic Finding of Anterior Spinal Artery Occlusion. Neurocrit Care. 2018 Jun; 28 (3):388-394
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  111. McLaughlin DC, Margretta MM, Freeman WD. Aneurysmal Subarachnoid Hemorrhage Mortality After Implementation of Nocturnist Advanced Practice Provider Coverage. J Neurosci Nurs. 2018 Apr; 50 (2):102-104
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  112. Tallarico RT, Pizzi MA, Freeman WD. Investigational drugs for vasospasm after subarachnoid hemorrhage. Expert Opin Investig Drugs. 2018 Apr; 27 (4):313-324 Epub 2018 Apr 06
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  113. Lopez-Chiriboga AS, Yoon JW, Siegel JL, Harriott AM, Pirris S, Eidelman BH, Freeman WD. Granulomatous Angiitis of the Central Nervous System Associated with Hodgkin's Lymphoma: Case Report and Literature Review. J Stroke Cerebrovasc Dis. 2018 Jan; 27 (1):e5-e8 Epub 2017 Sept 21
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  114. Brown SM, Fifield SW, Pizzi MA, Alejos D, Richie AN, Dinh TA, Cheshire WP Jr, Meek SE, Freeman WD. A Preliminary Observational Study of Anovulatory Uterine Bleeding After Aneurysmal Subarachnoid Hemorrhage. J Neurosci Nurs. 2017 Dec; 49 (6):363-371
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  115. Lowman p, Tomlinson A, Freeman WD. Hypothermia and Targeted Temperature Management after Cardiac Arrest Northeast Florida Medicine. 2017.
  116. Yoon JW, Chen RE, Han PK, Si P, Freeman WD, Pirris SM. Technical feasibility and safety of an intraoperative head-up display device during spine instrumentation. Int J Med Robot. 2017 Sep; 13 (3) Epub 2016 Aug 29
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  117. Torbey MT, Brophy GM, Varelas PN, Bosel J, Manno E, Bader MK, Suarez JI, Seder D, Freeman WD. Guidelines for Family-Centered Care in Neuro-ICU Populations: Caveats for Routine Palliative Care. Crit Care Med 2017 Jun; 45 (6):e620-e621
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  118. Barrett KM, Pizzi MA, Kesari V, TerKonda SP, Mauricio EA, Silvers SM, Habash R, Brown BL, Tawk RG, Meschia JF, Wharen R, Freeman WD. Ambulance-based assessment of NIH Stroke Scale with telemedicine: A feasibility pilot study. J Telemed Telecare. 2017 May; 23 (4):476-483 Epub 2016 May 13
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  119. Siegel JL, Pizzi MA, Freeman WD. Stroke Diagnosis and Treatment in the Emergency Department. JAMA Neurol 2017 Mar 1; 74 (3):362
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  120. Lopez Chiriboga AS, Yoon J, Siegel J, Dickson D, Freeman WD, Pirris S, Harriott A. Granulomatous Angiitis of the Central Nervous System Associated with Hodgkin’s Lymphoma Journal of Clinical Neuroscience.2017;
  121. Runjaic S, Nordeen JD, Soto-Arenall MW, Johns GS, Miller D, Brown B, Freeman WD. Safety and Efficacy of Intensified Antiplatelet Therapy in Patients Undergoing Neuroendovascular Procedures. J Vasc Interv Neurol. 2017 Jan; 9 (3):51-56
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  122. Pizzi MA, Kamireddi P, Tatum WO, Shih JJ, Jackson DA, Freeman WD. Transition from intravenous to enteral ketamine for treatment of nonconvulsive status epilepticus. J Intensive Care. 2017; 5:54 Epub 2017 Aug 08
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  123. Dhakal LP, Tatum WO, Freeman WD. Train of four stimulation artifact mimicking a seizure during computerized automated ICU EEG monitoring. Epilepsy Behav Case Rep. 2017; 8:69-72 Epub 2017 Sept 11
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  124. Manno EM, Freeman WD, Livesay S, Geocadin RG, Torbey M, Nyquist P, Hemphill C, Neurocritical Care Society, Dr Edward Manno, Neurocritical Care Society President. Expertise Matters. Crit Care Med 2016 Nov; 44 (11):e1147-e1148
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  125. Burrell C, Avalon NE, Siegel J, Pizzi M, Dutta T, Charlesworth MC, Freeman WD. Precision medicine of aneurysmal subarachnoid hemorrhage, vasospasm and delayed cerebral ischemia. Expert Rev Neurother. 2016 Nov; 16 (11):1251-1262 Epub 2016 July 11
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  126. Dhakal LP, Harriott AM, Capobianco DJ, Freeman WD. Headache and Its Approach in Today's NeuroIntensive Care Unit. Neurocrit Care. 2016 Oct; 25 (2):320-34
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  127. Siegel J, Freeman WD, Broderick DF, Robles H, Thiel DD, Wszolek ZK. Ostry pooperacyjny zespól kr?gowo-podstawny – znaczenia lokalizacji klinicznej (Polish) [Postoperative acute vertebrobasilar syndrome – the importance of clinical localization]. Medycyna Praktyczna Neurologia 2016.2016;()3:61-66.
  128. Pizzi MA, Alejos DA, Siegel JL, Kim BY, Miller DA, Freeman WD. Cerebral Venous Thrombosis Associated with Intracranial Hemorrhage and Timing of Anticoagulation after Hemicraniectomy. J Stroke Cerebrovasc Dis. 2016 Sep; 25 (9):2312-6 Epub 2016 June 16
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  129. Dhakal LP, Sen A, Stanko CM, Rawal B, Heckman MG, Hoyne JB, Dimberg EL, Freeman ML, Ng LK, Rabinstein AA, Freeman WD. Early Absent Pupillary Light Reflexes After Cardiac Arrest in Patients Treated with Therapeutic Hypothermia. Ther Hypothermia Temp Manag. 2016 Aug; 6 (3):116-21 Epub 2016 May 02
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  130. Freeman WD. Proton Pump Inhibitors and Dementia Incidence. JAMA Neurol 2016 Aug 1; 73 (8):1026-7
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  131. Freeman WD, Sebesto J, Tawk RG. Letter to the Editor: Dural arteriovenous fistula mimicking Creutzfeldt-Jakob disease. J Neurosurg 2016 Jul; 125 (1):231-2 Epub 2016 Apr 22
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  132. Lopez Chiriboga AS, Yoon JW, Freeman WD, Odunukan OW, Cheshire WP Jr. Takotsubo cardiomyopathy in the setting of acute hydrocephalus secondary to neurocysticercosis. Clin Auton Res. 2016 Jun; 26 (3):235-41 Epub 2016 Mar 07
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  133. Dredla B, Freeman WD. Ehrlichia Meningitis Mimicking Aneurysmal Subarachnoid Hemorrhage: A Case Study for Medical Decision-Making Heuristics. Neurohospitalist. 2016 Apr; 6 (2):76-9 Epub 2015 Aug 02
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  134. Tawk RG, Grewal SS, Heckman MG, Rawal B, Miller DA, Edmonston D, Ferguson JL, Navarro R, Ng L, Brown BL, Meschia JF, Freeman WD. The Relationship Between Serum Neuron-Specific Enolase Levels and Severity of Bleeding and Functional Outcomes in Patients With Nontraumatic Subarachnoid Hemorrhage. Neurosurgery. 2016 Apr; 78 (4):487-91
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  135. Festic E, Soto JS, Pitre LA, Leveton M, Ramsey DM, Freeman WD, Heckman MG, Lee AS. Novel Bedside Phonetic Evaluation to Identify Dysphagia and Aspiration Risk. Chest. 2016 Mar; 149(3):649-59. Epub 2016 Jan 12.
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  136. Sridharan M, Wysokinski WE, Pruthi R, Oyen L, Freeman WD, Rabinstein AA, McBane RD. Periprocedural warfarin reversal with prothrombin complex concentrate. Thromb Res. 2016 Mar; 139:160-5 Epub 2015 Nov 18
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  137. Siegel J, Edwards E, Mooney L, Smith C, Smith C, Peel JB, Dole A, Maler P, Freeman WD. A feasibility pilot using a mobile personal health assistant (PHA) app to assist stroke patient and caregiver communication after hospital discharge. Mhealth. 2016; 2:31 Epub 2016 Aug 09
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  138. Freeman WD. "Management of intracranial pressure": Erratum CONTINUUM: Lifelong Learning in Neurology. 2015 Dec; 21: (6)1550.
  139. Freeman WD, Brazis PW, Biller J, Masdeu JC, Merrilees GR, Olson S. In Memoriam: Frank A. Rubino, MD. JAMA Neurol. 2015 Nov; 72: (11)1384-5.
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  140. Duello KM, Nagel JP, Thomas CS, Blackshear JL, Freeman WD. Relationship of Troponin T and Age- and Sex-Adjusted BNP Elevation Following Subarachnoid Hemorrhage with 30-Day Mortality. Neurocrit Care. 2015 Aug; 23(1):59-65.
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  141. Grewal SS, Lopez Del Valle EM, Gupta V, Ramon N, Freeman WD, Tawk RG. Neurological Changes with Abnormal Brain Reactivity Following Coiling of Cerebral Aneurysm. Possible Reactivity to Endovascular Devices and Material? J Vasc Interv Neurol. 2015 Jul; 8 (3):28-36
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  142. Arnold SM, Dinkins M, Mooney LH, Freeman WD, Rawal B, Heckman MG, Davis OA. Very early mobilization in stroke patients treated with intravenous recombinant tissue plasminogen activator. J Stroke Cerebrovasc Dis. 2015 Jun; 24(6):1168-73. Epub 2015 Apr 11.
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  143. Dhakal LP, Hodge DO, Nagel J, Mayes M, Richie A, Ng LK, Freeman WD. Erratum to: safety and tolerability of gabapentin for aneurysmal subarachnoid hemorrhage (SAH) headache and meningismus. Neurocrit Care. 2015 Jun; 22(3):422.
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  144. Dhakal LP, Hodge DO, Nagel J, Mayes M, Richie A, Ng LK, Freeman WD. Safety and tolerability of gabapentin for aneurysmal subarachnoid hemorrhage (sah) headache and meningismus. Neurocrit Care. 2015 Jun; 22(3):414-21.
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  145. Dhakal LP, Diaz-Gomez JL, Freeman WD. Role of anesthesia for endovascular treatment of ischemic stroke: do we need neurophysiological monitoring? Stroke. 2015 Jun; 46 (6):1748-54 Epub 2015 May 07
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  146. Dhakal LP, Bourgeois K, Barrett KM, Freeman WD. The "starfield" pattern of cerebral fat embolism from bone marrow necrosis in sickle cell crisis. Neurohospitalist. 2015 Apr; 5 (2):74-6
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  147. Cable CA, Freeman WD, Rubin MN, Khoor A, Karnatovskaia LV. A 51-year-old man with seizures and progressive behavioral changes. Chest. 2015 Mar; 147: (3)e86-e89.
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  148. Rubin MN, Barrett KM, Freeman WD, Lee Iannotti JK, Channer DD, Rabinstein AA, Demaerschalk BM. Teleneurosonology: a novel application of transcranial and carotid ultrasound. J Stroke Cerebrovasc Dis. 2015 Mar; 24 (3):562-5 Epub 2014 Dec 23
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  149. Tawk RG, Grewal SS, Heckman MG, Navarro R, Ferguson JL, Starke EL, Rawal B, Hanel R, Miller D, Wharen RE, Freeman WD. Influence of body mass index and age on functional outcomes in patients with subarachnoid hemorrhage. Neurosurgery. 2015 Feb; 76 (2):136-41
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  150. Pagan RJ, Parikh PP, Mergo PJ, Gerber TC, Mankad R, Freeman WD, Shapiro BP. Emerging role of cardiovascular CT and MRI in the evaluation of stroke. AJR Am J Roentgenol. 2015 Feb; 204(2):269-80.
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  151. Freeman WD. Management of intracranial pressure. CONTINUUM Lifelong Learn. Neurol. 2015; 21(5):1299-323.
  152. Freeman WD. Cerebral perfusion pressure versus intracranial pressure-driven therapy on outcomes. Crit Care Med 2015 Jan; 43 (1):e29
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  153. Cano EJ, Robinson MT, Eidelman BH, Sebesto JR, Helmer SE, Freeman WD. Asymmetric brain edema after cardiac transplantation: cerebroautoregulatory failure and relative hyperperfusion. Transplant Proc. 2015 Jan-Feb; 47 (1):194-7
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  154. Freeman WD, Vatz KA. The future of health care: going to the dogs? Front Neurol. 2015; 6:87 Epub 2015 May 08
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  155. Karnatovskaia LV, Lee AS, Festic E, Kramer CL, Freeman WD. Effect of prolonged therapeutic hypothermia on intracranial pressure, organ function, and hospital outcomes among patients with aneurysmal subarachnoid hemorrhage. Neurocrit Care. 2014 Dec; 21 (3):451-61
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  156. Sierra J, Hanel R, Mooney L, Freeman W. Differential considerations of TCD pulsatility (Gosling's) and resistance (Pourcelot) indices after AVM surgery. J Vasc Interv Neurol. 2014 Nov; 7 (4):41-3
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  157. Karnatovskaia LV, Wartenberg KE, Freeman WD. Therapeutic hypothermia for neuroprotection: history, mechanisms, risks, and clinical applications. Neurohospitalist. 2014 Jul; 4 (3):153-63
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  158. Hocker S, Tatum WO, LaRoche S, Freeman WD. Refractory and super-refractory status epilepticus--an update. Curr Neurol Neurosci Rep. 2014 Jun; 14 (6):452
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  159. Karnatovskaia LV, Festic E, Freeman WD, Lee AS. Effect of therapeutic hypothermia on gas exchange and respiratory mechanics: a retrospective cohort study. Ther Hypothermia Temp Manag. 2014 Jun; 4: (2)88-95.
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  160. Smith CC, Tatum WO, Gupta V, Pooley RA, Freeman WD. SPECT-negative SIRPIDs: less aggressive neurointensive care? J Clin Neurophysiol. 2014 Jun; 31(3):e6-10.
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  161. Festic E, Siegel J, Stritt M, Freeman WD. The utility of serum procalcitonin in distinguishing systemic inflammatory response syndrome from infection after aneurysmal subarachnoid hemorrhage. Neurocrit Care. 2014 Jun; 20 (3):375-81
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  162. Hanel RA, Taussky P, Dixon T, Miller DA, Sapin M, Nordeen JD, Tawk RG, Navarro R, Johns G, Freeman WD. Safety and efficacy of ticagrelor for neuroendovascular procedures. A single center initial experience. J Neurointerv Surg. 2014 May; 6 (4):320-2 Epub 2013 June 14
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  163. Lewandowski-Belfer JJ, Patel AV, Darracott RM, Jackson DA, Nordeen JD, Freeman WD. Safety and efficacy of repeated doses of 14.6 or 23.4 % hypertonic saline for refractory intracranial hypertension. Neurocrit Care. 2014; 20(3):436-42.
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  164. Ranasinghe T, Freeman WD. Vein of trolard sign on noncontrast computed tomography in Behcet's disease. Acta Med Acad. 2014; 43: (1)97-8.
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  165. Jackson DA, Patel AV, Darracott RM, Hanel RA, Freeman WD, Hanley DF. Safety of intraventricular hemorrhage (IVH) thrombolysis based on CT localization of external ventricular drain (EVD) fenestrations and analysis of EVD tract hemorrhage. Neurocrit Care. 2013 Aug; 19 (1):103-10
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  166. Aguilar MI, Kuo RS, Freeman WD. New anticoagulants (dabigatran, apixaban, rivaroxaban) for stroke prevention in atrial fibrillation. Neurol Clin. 2013 Aug; 31(3):659-75.
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  167. Taussky P, Tawk RG, Miller DA, Freeman WD, Hanel RA. New therapies for unruptured intracranial aneurysms. Neurol Clin. 2013 Aug; 31(3):737-47. Epub 2013 May 17.
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  168. Freeman WD, Vatz KA, Griggs RC, Pedley T. The Workforce Task Force report: clinical implications for neurology. Neurology. 2013 Jul 30; 81 (5):479-86 Epub 2013 June 19
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  169. Silva MD, Brazis P, Miller D, Wharen R, Smith CC, Freeman WD. True- true- unrelated? A deplayed onset, complete third-nerve palsy after traumatic subarachnoid hemorrhage. J Vasc Interv Neurol. 2013 Jun; 6(1):22-5.
  170. Nordeen JD, Patel AV, Darracott RM, Johns GS, Taussky P, Tawk RG, Miller DA, Freeman WD, Hanel RA. Clopidogrel Resistance by P2Y12 Platelet Function Testing in Patients Undergoing Neuroendovascular Procedures: Incidence of Ischemic and Hemorrhagic Complications. J Vasc Interv Neurol. 2013 Jun; 6 (1):26-34
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  171. Festic E, Rabinstein AA, Freeman WD, Mauricio EA, Robinson MT, Mandrekar J, Zubair AC, Lee AS, Gajic O. Blood transfusion is an important predictor of hospital mortality among patients with aneurysmal subarachnoid hemorrhage. Neurocrit Care. 2013 Apr; 18 (2):209-15
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  172. Cantador AA, Meschia JF, Freeman WD, Tatum WO. Nonconvulsive status with metronidazole The Neurohospitalist. 2013; 3: (4)185-9.
  173. Lewandowski-Belfer JJ, Patel AV, Darracott RM, Jackson DA, Nordeen JD, Freeman WD. Safety and efficacy of repeated doses of 14.6 or 23.4% hypertonic saline for refractory intracranial hypertension. Neurocrit Care. 2013.
  174. Likosky DJ, Josephson SA, Coleman M, Freeman WD, Biller J. Survey of current neurohospitalist practice. Neurol Clin Pract. 2012 Dec; 2 (4):319-327
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  175. Freeman WD, Barrett KM, Vatz KA, Demaerschalk BM. Future neurohospitalist: teleneurohospitalist. Neurohospitalist. 2012 Oct; 2 (4):132-43
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  176. Douglas VC, Scott BJ, Berg G, Freeman WD, Josephson SA. Effect of a neurohospitalist service on outcomes at an academic medical center. Neurology. 2012 Sep 4; 79(10):988-94. Epub 2012 Aug 22.
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  177. Luk ME, Tatum WO, Patel AV, Nau KM, Freeman WD. The safety of lacosamide for treatment of seizures and seizure prophylaxis in adult hospitalized patients. Neurohospitalist. 2012 Jul; 2(3):77-81.
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  178. Rahmlow MR, Boylan K, Freeman WD. Diaphragmatic pacing to facilitate ventilator weaning in neuromyelitis optica-associated respiratory failure. Mult Scler Relat Disord. 2012 Jul; 1(3):145-7. Epub 2012 Apr 07.
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  179. Lu N, Jackson D, Luke S, Festic E, Hanel RA, Freeman WD. Intraventricular nicardipine for aneurysmal subarachnoid hemorrhage related vasospasm: assessment of 90 days outcome. Neurocrit Care. 2012 Jun; 16 (3):368-75
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  180. Kramer C, Freeman WD, Larson JS, Hoffman-Snyder C, Wellik KE, Hoffman-Snyder C, Demaerschalk BM, Wingerchuk DM. Therapeutic hypothermia for severe traumatic brain injury: a critically appraised topic. Neurologist. 2012 May; 18 (3):173-7
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  181. Rabinstein AA, Yee AH, Mandrekar J, Fugate JE, de Groot YJ, Kompanje EJ, Shutter LA, Freeman WD, Rubin MA, Wijdicks EF. Prediction of potential for organ donation after cardiac death in patients in neurocritical state: a prospective observational study. Lancet Neurol. 2012 May; 11 (5):414-9 Epub 2012 Apr 10
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  182. Carrigan WV 3rd, Barrett K, Freeman WD, Avalon N. Multimodal CT to Differentiate Acute Ischemic Stroke From Stroke Mimics. Neurohospitalist. 2012 Apr; 2 (2):60-1
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  183. Taussky P, O'Neal B, Daugherty WP, Luke S, Thorpe D, Pooley RA, Evans C, Hanel RA, Freeman WD. Validation of frontal near-infrared spectroscopy as noninvasive bedside monitoring for regional cerebral blood flow in brain-injured patients. Neurosurg Focus. 2012 Feb; 32 (2):E2
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  184. Freeman WD, Aguilar MI. Intracranial hemorrhage: diagnosis and management. Neurol Clin. 2012 Feb; 30: (1)211-40, ix.
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  185. Cyrous A, O'Neal B, Freeman WD. New approaches to bedside monitoring in stroke. Expert rev. neurotherapeutics. 2012; 12(8):915-28.
  186. Freeman WD, Dorsher PT, Safford RE, Van Gerpen J, Edwards WD. Combined pergolide-associated valvular heart disease and achilles tendon contractures. Acta Med Acad. 2012; 41(2):228-30.
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  187. Chiota NA, Freeman WD, Barrett KM. Hypoxic-ischemic brain injury and prognosis after cardiac arrest. Continuum. 2011 Oct; 17(5):1094-118.
  188. Jerath NU, Reddy C, Freeman WD, Jerath AU, Brown RD. Gender differences in presenting signs and symptoms of acute ischemic stroke: a population-based study. Gend Med. 2011 Oct; 8 (5):312-9 Epub 2011 Sept 16
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  189. Walsh RD, Barrett KM, Aguilar MI, Lanzino G, Hanel RA, Miller DA, Chong BW, Freeman WD. Intracranial hemorrhage following neuroendovascular procedures with abciximab is associated with high mortality: a multicenter series. Neurocrit Care. 2011 Aug; 15 (1):85-95
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  190. Rancier R, Woessner H, Freeman WD. The diffuse hyperdense intracranial circulation sign. Neurohospitalist. 2011 Jul; 1 (3):137
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  191. Freeman WD, Aguilar MI. Prevention of cardioembolic stroke. Neurotherapeutics. 2011 Jul; 8 (3):488-502
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  192. Bacani CJ, Freeman WD, Di Trapani RA, Canabal JC, Arasi L, Shine T, Willingham DL. Emergent, controlled lumbar drainage for intracranial pressure monitoring during orthotopic liver transplantation. Neurocrit Care. 2011 Jun; 14 (3):447-52
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  193. Tatum WO, Dworetzky BA, Freeman WD, Schomer DL. Artifact: recording EEG in special care units. J Clin Neurophysiol. 2011 Jun; 28(3):264-77.
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  194. Freeman WD, Dawson SB, Raper C, Thiemann K, Josephson SA, Barrett KM. Neurohospitalists reduce length of stay for patients with ischemic stroke. Neurohospitalist. 2011 Apr; 1 (2):67-70
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  195. Freeman WD, Nolte CM, Matthews BR, Coleman M, Corboy JR. Results of the American Academy of Neurology resident survey. Neurology. 2011 Mar 29; 76 (13):e61-7
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  196. Freeman WD, Josephson SA. The birth of neurohospitalists. Neurohospitalist. 2011 Jan; 1 (1):5-7
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  197. Chiota NA, Freeman WD, Barrett K. Earlier Hypothermia Attainment is Associated with Improved Outcomes after Cardiac Arrest. J Vasc Interv Neurol. 2011 Jan; 4 (1):14-7
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  198. Mauricio EA, Freeman WD. Status epilepticus in the elderly: differential diagnosis and treatment. Neuropsychiatr Dis Treat. 2011; 7:161-6 Epub 2011 Mar 29
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  199. Smith EH, Gavrilov DK, Oglesbee D, Freeman WD, Vavra MW, Matern D, Tortorelli S. An adult onset case of alpha-methyl-acyl-CoA racemase deficiency. J Inherit Metab Dis. 2010 Dec; 33 Suppl 3:S349-53 Epub 2010 Sept 04
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  200. Aguilar MI, Freeman WD. Spontaneous intracerebral hemorrhage. Semin Neurol. 2010 Nov; 30 (5):555-64 Epub 2011 Jan 04
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  201. Freeman WD, Dawson SB, Flemming KD. The ABC's of stroke complications. Semin Neurol. 2010 Nov; 30(5):501-10. Epub 2011 Jan 04.
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  202. Robinson MT, Rabinstein AA, Meschia JF, Freeman WD. Safety of recombinant activated factor VII in patients with warfarin-associated hemorrhages of the central nervous system. Stroke. 2010 Jul; 41: (7)1459-63.
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  203. Freeman WD, Vatz KA. The future of neurology. Neurol Clin. 2010 May; 28(2):537-61.
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  204. Aguilar MI, Freeman WD. Treatment of coagulopathy in intracranial hemorrhage. Curr Treat Options Neurol. 2010 Mar; 12 (2):113-28
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  205. Albright KC, Freeman WD, Kruse BT. Cerebral venous thrombosis. J Emerg Med. 2010 Feb; 38: (2)238-9.
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  206. Barrett KM, Freeman WD. Emerging subspecialties in neurology: neurohospitalist. Neurology. 2010 Jan 12; 74 (2):e9-10
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  207. Freeman WD, Palmer S, Freeman ML, Barrett KM. Reversible delayed hypoxic leukoencephalopathy associated with methadone overdose. Acta Medica Academica. 2010; 39(1).
  208. Likosky D, Shulman S, Restrepo L, Freeman WD. Survey of neurohospitalists: Subspecialty definition and practice characteristics. Frontiers in Neurology. 2010; Jun:9.
  209. Freeman WD, Aguilar MI. Anticoagulation Therapy for Stroke: Risks and Benefits in the Aged. Aging Health. 2010.
  210. Freeman WD, Aguilar M. Anticoagulation therapy for cardioembolic stroke prevention in the elderly: Defining benefits and risks. Aging Health. 2010; 6(4):439-50.
  211. Mateen FJ, Nasser M, Spencer BR, Freeman WD, Shuaib A, Demaerschalk BM, Wijdicks EF. Outcomes of intravenous tissue plasminogen activator for acute ischemic stroke in patients aged 90 years or older. Mayo Clin Proc. 2009 Apr; 84 (4):334-8
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  212. Ng HK, Hanel R, Freeman W. Prolonged Mild-to-Moderate Hypothermia for Refractory Intracranial Hypertension. J Vasc Interv Neurol. 2009 Jan; 2 (1):142-6
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  213. Rowley M, Riutort K, Shapiro D, Casler J, Festic E, Freeman WD. Methylene blue-associated serotonin syndrome: a 'green' encephalopathy after parathyroidectomy. Neurocrit Care. 2009; 11 (1):88-93 Epub 2009 Mar 05
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  214. Nau KM, Divertie GD, Valentino AK, Freeman WD. Safety and efficacy of levetiracetam for critically ill patients with seizures. Neurocrit Care. 2009; 11 (1):34-7 Epub 2009 Jan 29
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  215. Spector AR, Freeman WD, Cheshire WP. The stroke that struck back: an unusual alien hand presentation. J Stroke Cerebrovasc Dis. 2009 Jan; 18(1):72-3.
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  216. Freeman WD, Aguilar MI. Stroke prevention in atrial fibrillation and other major cardiac sources of embolism. Neurol Clin. 2008 Nov; 26(4):1129-60, x-xi.
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  217. Rahmlow M, Shuster EA, Dominik J, Deen HG Jr, Dickson DW, Aksamit AJ Jr, Robles HA, Freeman WD. Leflunomide-associated progressive multifocal leukoencephalopathy. Arch Neurol. 2008 Nov; 65 (11):1538-9
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  218. Valentino AK, Nau KM, Miller DA, Hanel RA, Freeman W. Repeated dosing of 23.4% hypertonic saline for refractory intracranial hypertension. A case report. J Vasc Interv Neurol. 2008 Oct; 1 (4):113-7
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  219. Barrett KM, Freeman WD. 71-year-old woman with loss of right-sided vision and cognitive deficits. Mayo Clin Proc. 2008 Jun; 83(6):708-11.
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  220. Konieczny PL, Eidelman BH, Freeman WD. Teaching video neuroimage: Foix-Chavany-Marie syndrome. Neurology. 2008 May 20; 70: (21)e88.
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  221. Freeman WD, Gronseth G, Eidelman BH. Invited article: is it time for neurohospitalists? Neurology. 2008 Apr 8; 70 (15):1282-8 Epub 2008 Mar 12
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  222. Freeman WD, Aguilar MI. Management of warfarin-related intracerebral hemorrhage. Expert Rev Neurother. 2008 Feb; 8(2):271-90.
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  223. Manno EM, Rabinstein AA, Wijdicks EF, Brown AW, Freeman WD, Lee VH, Weigand SD, Keegan MT, Brown DR, Whalen FX, Roy TK, Hubmayr RD. A prospective trial of elective extubation in brain injured patients meeting extubation criteria for ventilatory support: a feasibility study. Crit Care. 2008; 12 (6):R138 Epub 2008 Nov 10
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  224. Freeman WD, Barrett KM, Bestic JM, Meschia JF, Broderick DF, Brott TG. Computer-assisted volumetric analysis compared with ABC/2 method for assessing warfarin-related intracranial hemorrhage volumes. Neurocrit Care. 2008; 9 (3):307-12
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  225. Aguilar MI, Freeman WD. Warfarin-related intracerebral hemorrhage: How to proceed. Aging Health. 2008; 4(3):299-310.
  226. Barrett KM, Freeman WD, Weindling SM, Brott TG, Broderick DF, Heckman MG, Crook JE, Divertie GD, Meschia JF. Brain injury after cardiopulmonary arrest and its assessment with diffusion-weighted magnetic resonance imaging. Mayo Clin Proc. 2007 Jul; 82(7):828-35.
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  227. Gill DJ, Freeman WD, Thoresen P, Corboy JR. Residency training the neurology resident case log: a national survey of neurology residents. Neurology. 2007 May 22; 68(21):E32-3.
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  228. Linos K, Foot C, Ziegenfuss M, Freeman WD, Tan KM. Critical illness weakness: Common questions. Curr Anaesth Crit Care. 2007; 18(5-6):252-60.
  229. Linos K, Fraser J, Freeman WD, Foot C. Care of the brain-dead organ donor. Curr Anaesth Crit Care. 2007; 18(5-6):284-94.
  230. Heaney M, Foot C, Freeman WD, Fraser J. Ethical issues in withholding and withdrawing life-prolonging medical treatment in the ICU. Curr Anaesth Crit Care. 2007; 18(5-6):277-83.
  231. Freeman WD, Tan KM, Glass GA, Linos K, Foot C, Ziegenfuss M. ICU management of patients with Parkinson's disease or Parkinsonism. Curr Anaesth Crit Care. 2007; 18(5-6):227-36.
  232. Aguilar MI, Hart RG, Kase CS, Freeman WD, Hoeben BJ, Garcia RC, Ansell JE, Mayer SA, Norrving B, Rosand J, Steiner T, Wijdicks EF, Yamaguchi T, Yasaka M. Treatment of warfarin-associated intracerebral hemorrhage: literature review and expert opinion. Mayo Clin Proc. 2007 Jan; 82: (1)82-92.
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  233. Freeman WD, Sen S, Roy TK, Wijdicks EF. Cluster breathing associated with bihemispheric infarction and sparing of the brainstem. Arch Neurol. 2006 Oct; 63(10):1487-90.
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  234. Freeman WD, Brott TG. Modern treatment options for intracerebral hemorrhage. Curr Treat Options Neurol. 2006 Mar; 8 (2):145-57
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  235. Baba Y, Hentschel K, Freeman WD, Broderick DF, Wszolek ZK. Large paraspinal and iliopsoas muscle hematomas. Archives of Neurology. 2005 Aug; 62(8):1306.
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  236. Freeman WD, Chabolla DR. 36-Year-old woman with loss of consciousness, fever, and tachycardia. Mayo Clin Proc. 2005 May; 80 (5):667-70
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  237. Freeman WD, Cheshire WP. A callused clue fingers the diagnosis. Arch Neurol. 2005 Mar; 62(3):491.
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  238. Freeman WD, Maramattom B, Czervionke L, Manno EM. Pituitary apoplexy. Neurocrit Care. 2005; 3 (2):174-6
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  239. Freeman WD, Brott TG, Barrett KM, Castillo PR, Deen HG Jr, Czervionke LF, Meschia JF. Recombinant factor VIIa for rapid reversal of warfarin anticoagulation in acute intracranial hemorrhage. Mayo Clin Proc. 2004 Dec; 79: (12)1495-500.
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