Publications Print Zhao-Fleming H, Rezk M, Shah S, Gupta P, Zekeridou A, Flanagan EP, Pittock SJ, McKeon A, Dubey D. Comprehensive Analysis of Paraneoplastic Neurologic Syndrome and PNS-CARE Diagnostic Criteria in Clinical Practice. Neurol Neuroimmunol Neuroinflamm. 2024 Dec; 11 (6):e200316 Epub 2024 Sept 25 View PubMed Vorasoot N, Abdulrahman YJ, Mateen F, Fryer JP, Redenbaugh V, Sagen JA, Musubire AK, Jenkins SM, Gorsh AP, Chen JJ, Zekeridou A, McKeon A, Flanagan EP, Mills JR, Pittock SJ. Dried blood spot improves global access to aquaporin-4-IgG testing for neuromyelitis optica. Ann Clin Transl Neurol. 2024 Oct 15 [Epub ahead of print] View PubMed Nathoo N, Neyal N, Atkinson EJ, Weinshenker BG, Tillema JM, Keegan BM, Pittock SJ, Tobin WO, Flanagan EP, Gavrilova R, Toledano M, Young N, Truitt K, Okuda DT, Zeydan B, Kantarci OH. Multiple sclerosis in Somali Americans: Nature or nurture? Mult Scler Relat Disord. 2024 Oct; 90:105842 Epub 2024 Aug 29 View PubMed Mangioris G, Pittock SJ, Yang B, Fryer JP, Harmsen WS, Dubey D, Flanagan EP, Lopez-Chiriboga SA, McKeon A, Mills JR, Vodopivec I, Tobin WO, Toledano M, Aksamit AJ, Zekeridou A. Cerebrospinal Fluid Cytokine and Chemokine Profiles in Central Nervous System Sarcoidosis: Diagnostic and Immunopathologic Insights. Ann Neurol. 2024 Oct; 96 (4):704-714 Epub 2024 July 19 View PubMed Tisavipat N, Rattanathamsakul N, Salman AR, Cacciaguerra L, Pittock SJ, Flanagan EP, Chen JJ. Intracranial Pressure Elevation and MOGAD. JAMA Neurol. 2024 Sep 16 Epub 2024 Sept 16 View PubMed Mangioris G, Orozco E, Dubey D, Flanagan EP, Pittock SJ, Zekeridou A, McKeon A. Long-term outcomes in antibody-negative autoimmune encephalitis: a retrospective study. J Neurol. 2024 Sep 15 Epub 2024 Sept 15 View PubMed Klyscz P, Asseyer S, Alonso R, Bereuter C, Bialer O, Bick A, Carta S, Chen JJ, Cohen L, Cohen-Tayar Y, Carnero Contentti E, Dale RC, Flanagan EP, Gernert JA, Haas J, Havla J, Heesen C, Hellmann M, Levin N, Lopez P, Lotan I, Luis MB, Mariotto S, Mayer C, Vergara AJM, Ocampo C, Ochoa S, Oertel FC, Olszewska M, Uribe JLP, Sastre-Garriga J, Scocco D, Ramanathan S, Rattanathamsakul N, Shi FD, Shifa J, Simantov I, Siritho S, Tiosano A, Tisavipat N, Torres I, Dembinsky AV, Vidal-Jordana A, Wilf-Yarkoni A, Wu T, Zamir S, Zarco LA, Zimmermann HG, Petzold A, Paul F, Stiebel-Kalish H. Application of the international criteria for optic neuritis in the Acute Optic Neuritis Network. Ann Clin Transl Neurol. 2024 Sep; 11 (9):2473-2484 Epub 2024 Aug 04 View PubMed Tajfirouz D, Madhavan A, Pacheco Marrero JM, Krecke KN, Fautsch KJ, Flanagan EP, Pittock SJ, Shah S, Bhatti MT, Chen JJ. Frequency of Asymptomatic Optic Nerve Enhancement in 203 Patients With MOG Antibody-Associated Disease. Neurol Neuroimmunol Neuroinflamm. 2024 Sep; 11 (5):e200277 Epub 2024 June 26 View PubMed Handzic A, Xie JS, Tisavipat N, O'Cearbhaill RM, Tajfirouz DA, Chodnicki KD, Flanagan EP, Chen JJ, Micieli J, Margolin E. Radiologic Predictors of Visual Outcome in Myelin Oligodendrocyte Glycoprotein-Related Optic Neuritis. Ophthalmology. 2024 Aug 14 [Epub ahead of print] View PubMed Keegan BM, Messina SA, Hanson D, Holmes D, Camp J, Sechi E, Nayak S, Barakat B, Ahmad R, Mandrekar J, Harmsen WS, Kantarci O, Weinshenker BG, Flanagan EP. MR Imaging Features of Critical Spinal Demyelinating Lesions Associated with Progressive Motor Impairment. AJNR Am J Neuroradiol. 2024 Jul 8; 45 (7):943-950 Epub 2024 July 08 View PubMed Virupakshaiah A, Schoeps VA, Race J, Waltz M, Sharayah S, Nasr Z, Moseley CE, Zamvil SS, Gaudioso C, Schuette A, Casper TC, Rose J, Flanagan EP, Rodriguez M, Tillema JM, Chitnis T, Gorman MP, Graves JS, Benson LA, Rensel M, Abrams A, Krupp L, Lotze TE, Aaen G, Wheeler Y, Schreiner T, Waldman A, Chong J, Mar S, Waubant E. Predictors of a relapsing course in myelin oligodendrocyte glycoprotein antibody-associated disease. J Neurol Neurosurg Psychiatry. 2024 Jul 4 Epub 2024 July 04 View PubMed Hagbohm C, Ouellette R, Flanagan EP, Jonsson DI, Piehl F, Banwell B, Wickstrom R, Iacobaeus E, Granberg T, Ineichen BV. Clinical and neuroimaging phenotypes of autoimmune glial fibrillary acidic protein astrocytopathy: A systematic review and meta-analysis. Eur J Neurol. 2024 Jul; 31 (7):e16284 Epub 2024 Mar 20 View PubMed Syc-Mazurek SB, Zhao-Fleming H, Guo Y, Tisavipat N, Chen JJ, Zekeridou A, Kournoutas I, Orme JJ, Block MS, Lucchinetti CF, Mustafa R, Flanagan EP. MOG Antibody-Associated Disease in the Setting of Metastatic Melanoma Complicated by Immune Checkpoint Inhibitor Use. Neurol Neuroimmunol Neuroinflamm. 2024 Jul; 11 (4):e200249 Epub 2024 May 02 View PubMed Redenbaugh V, Fryer JP, Cacciaguerra L, Chen JJ, Greenwood TM, Gilligan M, Thakolwiboon S, Majed M, Chia NH, McKeon A, Mills JR, Lopez Chiriboga AS, Tillema JM, Yang B, Abdulrahman Y, Guo K, Vorasoot N, Valencia Sanchez C, Tajfirouz DA, Toledano M, Zekeridou A, Dubey D, Gombolay GY, Caparo-Zamalloa C, Kister I, Pittock SJ, Flanagan EP. Diagnostic Utility of MOG Antibody Testing in Cerebrospinal Fluid. Ann Neurol. 2024 Jul; 96 (1):34-45 Epub 2024 Apr 09 View PubMed Estrela T, Stiebel-Kalish H, Rettenmaier L, Henderson AD, Sotirchos E, Said Y, Ahmadi G, Tajfirouz DA, Flanagan EP, Tisavipat N, Gise R, Chwalisz BK, Chen JJ. Optic Disc Cupping in Neuromyelitis Optica Spectrum Disorder, Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease, and Multiple Sclerosis and Its Relationship With Optical Coherence Tomography Parameters: A Multicenter Study. J Neuroophthalmol. 2024 Jul 1 Epub 2024 July 01 View PubMed Pluvinage JV, Ngo T, Fouassier C, McDonagh M, Holmes BB, Bartley CM, Kondapavulur S, Hurabielle C, Bodansky A, Pai V, Hinman S, Aslanpour A, Alvarenga BD, Zorn KC, Zamecnik C, McCann A, Asencor AI, Huynh T, Browne W, Tubati A, Haney MS, Douglas VC, Louine M, Cree BAC, Hauser SL, Seeley W, Baranzini SE, Wells JA, Spudich S, Farhadian S, Ramachandran PS, Gillum L, Hales CM, Zikherman J, Anderson MS, Yazdany J, Smith B, Nath A, Suh G, Flanagan EP, Green AJ, Green R, Gelfand JM, DeRisi JL, Pleasure SJ, Wilson MR. Transcobalamin receptor antibodies in autoimmune vitamin B12 central deficiency. Sci Transl Med. 2024 Jun 26; 16 (753):eadl3758 Epub 2024 June 26 View PubMed Nathoo N, Uhm JH, Porter AB, Hammack J, Jaeckle KA, Mrugala MM, Crum BA, Flanagan EP, Pittock SJ, Goyal G, Young JR, Koster MJ, Vassallo R, Ryu JH, Davidge-Pitts CJ, Bach C, Ravindran A, Sartori Valinotti JC, Bennani NN, Abeykoon JP, Shah MV, Hook CC, Rech KL, Go RS, Tobin WO, Mayo Clinic-University of Alabama at Birmingham Histiocytosis Working Group. Clinical features and outcomes in primary nervous system histiocytic neoplasms. Blood Cancer J 2024 Jun 20; 14 (1):101 Epub 2024 June 20 View PubMed Kraker JA, Xu SC, Flanagan EP, Foster R, Wang F, Chen JJ. Ocular Manifestations of Multiple Sclerosis: A Population-Based Study. J Neuroophthalmol. 2024 Jun 1; 44 (2):157-161 Epub 2024 Mar 08 View PubMed Mangioris G, Halfdanarson TR, Lennon VA, Chang BK, Dubey D, Dyck PJB, Flanagan EP, McKeon A, Mills JR, Pittock SJ, Zekeridou A. Neurological autoimmunity in patients with non-pulmonary neuroendocrine neoplasms: clinical manifestations and neural autoantibody profiles. Eur J Neurol. 2024 Jun; 31 (6):e16273 Epub 2024 Mar 11 View PubMed Li X, Gupta P, Smith KM, Madhavan A, Rezk M, Zekeridou A, Flanagan EP, McKeon A, Pittock SJ, Britton JW, Dubey D. Seizure-Related Falls and Near Falls in LGI1-IgG Autoimmune Encephalitis. Neurol Clin Pract. 2024 Jun; 14 (3):e200301 Epub 2024 May 07 View PubMed Cacciaguerra L, Abdel-Mannan O, Champsas D, Mankad K, Krecke KN, Chen JJ, Syc-Mazurek SB, Redenbaugh V, Lopez-Chiriboga AS, Valencia-Sanchez C, Hemingway C, Tillema JM, Ciccarelli O, Pittock SJ, Hacohen Y, Flanagan EP. Radiologic Lag and Brain MRI Lesion Dynamics During Attacks in MOG Antibody-Associated Disease. Neurology. 2024 May 28; 102 (10):e209303 Epub 2024 May 06 View PubMed Flanagan EP. Aspergillus myelitis: Breaking the mold to make a diagnosis. Mult Scler 2024 May; 30 (6):758-759 Epub 2024 Mar 07 View PubMed Kelly MJ, Grant E, Murchison AG, Binks S, Ramanathan S, Michael S, Handel AE, Handunnetthi L, Uy CE, Soltys JN, Dubey D, Day GS, Lopez-Chiriboga AS, Flanagan EP, Sheerin F, Irani SR. Magnetic Resonance Imaging Characteristics of LGI1-Antibody and CASPR2-Antibody Encephalitis. JAMA Neurol. 2024 May 1; 81 (5):525-533 View PubMed Tisavipat N, Stiebel-Kalish H, Palevski D, Bialer OY, Moss HE, Chaitanuwong P, Padungkiatsagul T, Henderson AD, Sotirchos ES, Singh S, Salman AR, Tajfirouz DA, Chodnicki KD, Pittock SJ, Flanagan EP, Chen JJ. Acute Optic Neuropathy in Older Adults: Differentiating Between MOGAD Optic Neuritis and Nonarteritic Anterior Ischemic Optic Neuropathy. Neurol Neuroimmunol Neuroinflamm. 2024 May; 11 (3):e200214 Epub 2024 Mar 28 View PubMed Pinto E Vairo F, Kemppainen JL, Vitek CRR, Whalen DA, Kolbert KJ, Sikkink KJ, Kroc SA, Kruisselbrink T, Shupe GF, Knudson AK, Burke EM, Loftus EC, Bandel LA, Prochnow CA, Mulvihill LA, Thomas B, Gable DM, Graddy CB, Garzon GGM, Ekpoh IU, Porquera EMC, Fervenza FC, Hogan MC, El Ters M, Warrington KJ, Davis JM 3rd, Koster MJ, Orandi AB, Basiaga ML, Vella A, Kumar S, Creo AL, Lteif AN, Pittock ST, Tebben PJ, Abate EG, Joshi AY, Ristagno EH, Patnaik MS, Schimmenti LA, Dhamija R, Sabrowsky SM, Wierenga KJ, Keddis MT, Samadder NJJ, Presutti RJ, Robinson SI, Stephens MC, Roberts LR, Faubion WA Jr, Driscoll SW, Wong-Kisiel LC, Selcen D, Flanagan EP, Ramanan VK, Jackson LM, Mauermann ML, Ortega VE, Anderson SA, Aoudia SL, Klee EW, McAllister TM, Lazaridis KN. Correction: Implementation of genomic medicine for rare disease in a tertiary healthcare system: Mayo Clinic Program for Rare and Undiagnosed Diseases (PRaUD). J Transl Med. 2024 Apr 30; 22 (1):400 View PubMed Gupta P, Paul P, Redenbaugh V, Guo Y, Lucchinetti C, Abdulrahman Y, Datta A, Shah S, Klein CJ, Pittock SJ, Flanagan EP, Dubey D. Peripheral nervous system manifestations of MOG antibody associated disease. Ann Clin Transl Neurol. 2024 Apr; 11 (4):1046-1052 Epub 2024 Jan 17 View PubMed Budhram A, Irani SR, Flanagan EP. Looking Beyond Syndrome-Based Criteria for Autoimmune Encephalitis-The Need for Complementary Neural Antibody-Based Diagnostic Criteria. JAMA Neurol. 2024 Mar 1; 81 (3):227-228 View PubMed Cacciaguerra L, Flanagan EP. Updates in NMOSD and MOGAD Diagnosis and Treatment: A Tale of Two Central Nervous System Autoimmune Inflammatory Disorders. Neurol Clin. 2024 Feb; 42 (1):77-114 Epub 2023 Aug 07 View PubMed Montalvo M, Flanagan EP. Paraneoplastic/autoimmune myelopathies. Handb Clin Neurol. 2024; 200:193-201 View PubMed Budhram A, Flanagan EP. Optimizing the diagnostic performance of neural antibody testing for paraneoplastic and autoimmune encephalitis in clinical practice. Handb Clin Neurol. 2024; 200:365-382 View PubMed Carta S, Dinoto A, Capobianco M, Valentino P, Montarolo F, Sala A, Reindl M, Lo Re M, Chiodega V, Branger P, Audoin B, Aboab J, Papeix C, Collongues N, Kerschen P, Zephir H, Creange A, Bourre B, Schanda K, Flanagan EP, Redenbaugh V, Villacieros-Alvarez J, Arrambide G, Cobo-Calvo A, Ferrari S, Marignier R, Mariotto S. Serum Biomarker Profiles Discriminate AQP4 Seropositive and Double Seronegative Neuromyelitis Optica Spectrum Disorder. Neurol Neuroimmunol Neuroinflamm. 2024 Jan; 11 (1):e200188 Epub 2023 Dec 22 View PubMed Flanagan EP, Dubey D. Autoimmune neuromuscular disorders associated with neural antibodies. CONTINUUM Lifelong Learning in Neurology. 2024; 30 (4):1136-59 Samadzadeh S, Adnan R, Berglova P, Barzegar M, Debrabant B, Roikjaer SG, Levy M, Petzold A, Palace J, Flanagan EP, Mariotto S, Skou ST, Froelich A, Lotan I, Messina S, Geraldes R, Asseyer S, Stiebel-Kalish H, Oertel FC, Shaygannejad V, Sahraian MA, Kim HJ, Bennett JL, Bottcher C, Zimmermann HG, Weinshenker BG, Paul F, Asgari N. Protocol of a prospective multicenter study on comorbidity impact on multiple sclerosis and antibody-mediated diseases of the central nervous system (COMMIT). Front Immunol. 2024; 15:1380025 Epub 2024 July 02 View PubMed Elsbernd P, Cacciaguerra L, Krecke KN, Chen JJ, Gritsch D, Lopez-Chiriboga AS, Sechi E, Redenbaugh V, Morris PP, Carter JL, Wingerchuk DM, Tillema JM, Valencia-Sanchez C, Thakolwiboon S, Pittock SJ, Flanagan EP. Cerebral enhancement in MOG antibody-associated disease. J Neurol Neurosurg Psychiatry. 2023 Dec 14; 95 (1):14-18 View PubMed Rode MM, Itoh C, Martinez-Sosa S, Ebner BA, Chang BK, Flanagan EP, Pinto MV. Systematic approach to diagnosing suspected Creutzfeldt-Jakob disease. BMJ Case Rep. 2023 Dec 7; 16 (12) Epub 2023 Dec 07 View PubMed Cohen DA, Tajfirouz D, Vodopivec I, Kyle K, Bouffard MA, Bhattacharyya S, Douglas VC, Rasool N, Bhatti MT, McKeon A, Pittock S, Flanagan EP, Prasad S, Nagagopal V, Egan RA, Chen JJ, Chwalisz BK. Fluorescein Angiography Findings in Susac Syndrome: A Multicenter Retrospective Case Series. J Neuroophthalmol. 2023 Dec 1; 43 (4):481-490 Epub 2023 Apr 19 View PubMed Samadzadeh S, Olesen MN, Wirenfeldt M, Moller S, Misu T, Soelberg K, Frederiksen JL, Heegaard S, Mariotto S, Fujihara K, Ruprecht K, Andersen TL, Marignier R, Lillevang ST, Flanagan EP, Pittock SJ, Kim HJ, Bennett JL, Paul F, Sorensen GL, Weinshenker BG, Lassmann H, Asgari N. Microfibrillar-associated protein 4 as a potential marker of acute relapse in inflammatory demyelinating diseases of the central nervous system: Pathological and clinical aspects. Mult Scler. 2023 Dec; 29 (14):1721-1735 Epub 2023 Oct 13 View PubMed Li X, Krecke KN, Weinshenker BG, Clarke MJ, Zekeridou A, Toledano M, Flanagan EP. Hemicord White Matter Enhancement and the Croissant Sign in Cervical Spondylotic Myelopathy. Neurology. 2023 Nov 21; 101 (21):968-969 Epub 2023 Aug 30 View PubMed Griffin KJ, Toledano M, Flanagan EP, Mustafa R. "Trident Sign" in Primary CNS B-Cell Spinal Cord Lymphoma. Neurology. 2023 Nov 7; 101 (19):857-858 Epub 2023 Aug 30 View PubMed Mustafa R, Flanagan EP, Duffy DJ, Weinshenker BG, Soldan MMP, Kunchok A, Kaisey M, Solomon AJ. Laboratory evaluation for the differential diagnosis of possible multiple sclerosis in the United States: A physician survey. J Neurol Sci. 2023 Oct 15; 453:120781 Epub 2023 Sept 01 View PubMed Majed M, Valencia Sanchez C, Bennett JL, Fryer J, Mulligan MD, Redenbaugh V, McKeon A, Mills JR, Wingerchuk DM, Lennon VA, Weinshenker B, Chen JJ, Flanagan EP, Pittock SJ, Kunchok A. Alterations in Aquaporin-4-IgG Serostatus in 986 Patients: A Laboratory-Based Longitudinal Analysis. Ann Neurol. 2023 Oct; 94 (4):727-735 Epub 2023 July 05 View PubMed Zara P, Dinoto A, Carta S, Floris V, Turilli D, Budhram A, Ferrari S, Milia S, Solla P, Mariotto S, Flanagan EP, Lopez Chiriboga AS, Sechi E. Non-demyelinating disorders mimicking and misdiagnosed as NMOSD: a literature review. Eur J Neurol. 2023 Oct; 30 (10):3367-3376 Epub 2023 July 19 View PubMed Cacciaguerra L, Redenbaugh V, Chen JJ, Morris P, Sechi E, Syc-Mazurek SB, Lopez-Chiriboga AS, Tillema JM, Rocca MA, Filippi M, Pittock SJ, Flanagan EP. Timing and Predictors of T2-Lesion Resolution in Patients With Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease. Neurology. 2023 Sep 26; 101 (13):e1376-e1381 Epub 2023 June 19 View PubMed McKeon A, Lesnick C, Vorasoot N, Buckley MW, Dasari S, Flanagan EP, Gilligan M, Lafrance-Corey R, Miske R, Pittock SJ, Scharf M, Yang B, Zekeridou A, Dubey D, Mills J. Utility of Protein Microarrays for Detection of Classified and Novel Antibodies in Autoimmune Neurologic Disease. Neurol Neuroimmunol Neuroinflamm. 2023 Sep; 10 (5) Epub 2023 Aug 07 View PubMed Fereidan-Esfahani M, Decker PA, Weigand SD, Lopez Chiriboga AS, Flanagan EP, Tillema JM, Lucchinetti CF, Eckel-Passow JE, Tobin WO. Defining the natural history of tumefactive demyelination: A retrospective cohort of 257 patients. Ann Clin Transl Neurol. 2023 Sep; 10 (9):1544-1555 Epub 2023 July 13 View PubMed Smith KM, Britton JW, Thakolwiboon S, Chia NH, Gupta P, Flanagan EP, Zekeridou A, Lopez Chiriboga AS, Valencia Sanchez C, McKeon A, Pittock SJ, Dubey D. Seizure characteristics and outcomes in patients with neurological conditions related to high-risk paraneoplastic antibodies. Epilepsia. 2023 Sep; 64 (9):2385-2398 Epub 2023 July 04 View PubMed Chen B, Gomez-Figueroa E, Redenbaugh V, Francis A, Satukijchai C, Wu Y, Messina S, Sa M, Woodhall M, Paul F, Robertson NP, Lim M, Wassmer E, Kneen R, Huda S, Blain C, Halfpenny C, Hemingway C, O'Sullivan E, Hobart J, Fisniku LK, Martin RJ, Dobson R, Cooper SA, Williams V, Waters P, Chen JJ, Pittock SJ, Ramdas S, Leite MI, Flanagan EP, Geraldes R, Palace J. Do Early Relapses Predict the Risk of Long-Term Relapsing Disease in an Adult and Paediatric Cohort with MOGAD? Ann Neurol. 2023 Sep; 94 (3):508-517 Epub 2023 July 12 View PubMed Chen JJ, Flanagan EP, Pittock SJ, Stern NC, Tisavipat N, Bhatti MT, Chodnicki KD, Tajfirouz DA, Jamali S, Kunchok A, Eggenberger ER, Nome MAD, Sotirchos ES, Vasileiou ES, Henderson AD, Arnold AC, Bonelli L, Moss HE, Navarro SEV, Padungkiatsagul T, Stiebel-Kalish H, Lotan I, Wilf-Yarkoni A, Danesh-Meyer H, Ivanov S, Huda S, Forcadela M, Hodge D, Poullin P, Rode J, Papeix C, Saheb S, Boudot de la Motte M, Vignal C, Hacohen Y, Pique J, Maillart E, Deschamps R, Audoin B, Marignier R. Visual Outcomes Following Plasma Exchange for Optic Neuritis: An International Multicenter Retrospective Analysis of 395 Optic Neuritis Attacks. Am J Ophthalmol. 2023 Aug; 252:213-224 Epub 2023 Feb 21 View PubMed Valencia-Sanchez C, Sechi E, Dubey D, Flanagan EP, McKeon A, Pittock SJ, Zekeridou A. Immune checkpoint inhibitor-associated central nervous system autoimmunity. Eur J Neurol. 2023 Aug; 30 (8):2418-2429 Epub 2023 May 18 View PubMed Lotan I, Chen JJ, Hacohen Y, Abdel-Mannan O, Mariotto S, Huda S, Gibbons E, Wilf-Yarkoni A, Hellmann MA, Stiebel-Kalish H, Pittock SJ, Flanagan EP, Molazadeh N, Anderson M, Salky R, Romanow G, Schindler P, Duchow AS, Paul F, Levy M. Intravenous immunoglobulin treatment for acute attacks in myelin oligodendrocyte glycoprotein antibody disease. Mult Scler. 2023 Aug; 29 (9):1080-1089 Epub 2023 July 10 View PubMed Solomon AJ, Arrambide G, Brownlee WJ, Flanagan EP, Amato MP, Amezcua L, Banwell BL, Barkhof F, Corboy JR, Correale J, Fujihara K, Graves J, Harnegie MP, Hemmer B, Lechner-Scott J, Marrie RA, Newsome SD, Rocca MA, Royal W 3rd, Waubant EL, Yamout B, Cohen JA. Differential diagnosis of suspected multiple sclerosis: an updated consensus approach. Lancet Neurol. 2023 Aug; 22 (8):750-768 View PubMed Webb LM, Cacciaguerra L, Krecke KN, Chen JJ, Sechi E, Redenbaugh V, Dubey D, Pittock SJ, Flanagan EP. Marked central canal T2-hyperintensity in MOGAD myelitis and comparison to NMOSD and MS. J Neurol Sci. 2023 Jul 15; 450:120687 Epub 2023 May 12 View PubMed Flanagan EP, Waters PJ. Serum MOG-IgG titers should be performed routinely in the diagnosis and follow-up of MOGAD: No. Mult Scler. 2023 Jul; 29 (8):928-929 Epub 2023 May 25 View PubMed Chia NH, McKeon A, Dalakas MC, Flanagan EP, Bower JH, Klassen BT, Dubey D, Zalewski NL, Duffy D, Pittock SJ, Zekeridou A. Stiff person spectrum disorder diagnosis, misdiagnosis, and suggested diagnostic criteria. Ann Clin Transl Neurol. 2023 Jul; 10 (7):1083-1094 Epub 2023 May 22 View PubMed Tisavipat N, Chang BK, Ali F, Pittock SJ, Kammeyer R, Declusin A, Cohn SJ, Flanagan EP. Subacute Horizontal Diplopia, Jaw Dystonia, and Laryngospasm. Neurol Neuroimmunol Neuroinflamm. 2023 Jul; 10 (4) Epub 2023 June 13 View PubMed Meiling JB, Ha CT, Garlanger KL, Snider BA, Flanagan EP, Reeves RK. Inpatient rehabilitation outcomes in patients with the new diagnosis of COVID-19 tractopathy: a case series. Spinal Cord Ser Cases. 2023 Jul 1; 9 (1):25 Epub 2023 July 01 View PubMed Pinto E Vairo F, Kemppainen JL, Vitek CRR, Whalen DA, Kolbert KJ, Sikkink KJ, Kroc SA, Kruisselbrink T, Shupe GF, Knudson AK, Burke EM, Loftus EC, Bandel LA, Prochnow CA, Mulvihill LA, Thomas B, Gable DM, Graddy CB, Garzon GGM, Ekpoh IU, Porquera EMC, Fervenza FC, Hogan MC, El Ters M, Warrington KJ, Davis JM 3rd, Koster MJ, Orandi AB, Basiaga ML, Vella A, Kumar S, Creo AL, Lteif AN, Pittock ST, Tebben PJ, Abate EG, Joshi AY, Ristagno EH, Patnaik MS, Schimmenti LA, Dhamija R, Sabrowsky SM, Wierenga KJ, Keddis MT, Samadder NJJ, Presutti RJ, Robinson SI, Stephens MC, Roberts LR, Faubion WA Jr, Driscoll SW, Wong-Kisiel LC, Selcen D, Flanagan EP, Ramanan VK, Jackson LM, Mauermann ML, Ortega VE, Anderson SA, Aoudia SL, Klee EW, McAllister TM, Lazaridis KN. Implementation of genomic medicine for rare disease in a tertiary healthcare system: Mayo Clinic Program for Rare and Undiagnosed Diseases (PRaUD). J Transl Med. 2023 Jun 23; 21(1):410. View PubMed Yandamuri SS, Filipek B, Obaid AH, Lele N, Thurman JM, Makhani N, Nowak RJ, Guo Y, Lucchinetti CF, Flanagan EP, Longbrake EE, O'Connor KC. MOGAD patient autoantibodies induce complement, phagocytosis, and cellular cytotoxicity. JCI Insight. 2023 Jun 8; 8 (11) Epub 2023 June 08 View PubMed Redenbaugh V, Chia NH, Cacciaguerra L, McCombe JA, Tillema JM, Chen JJ, Lopez Chiriboga AS, Sechi E, Hacohen Y, Pittock SJ, Flanagan EP. Comparison of MRI T2-lesion evolution in pediatric MOGAD, NMOSD, and MS. Mult Scler. 2023 Jun; 29 (7):799-808 Epub 2023 May 23 View PubMed Ziaei A, Nasr Z, Hart J, Francisco C, Rutatangwa A, Leppert D, Kuhle J, Flanagan E, Waubant E. High serum neurofilament levels are observed close to disease activity events in pediatric-onset MS and MOG antibody-associated diseases. 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Corpus callosum involvement in MOG antibody-associated disease in comparison to AQP4-IgG-seropositive neuromyelitis optica spectrum disorder and multiple sclerosis. Mult Scler. 2023 May; 29 (6):748-752 Epub 2023 Jan 24 View PubMed Tisavipat N, Flanagan EP. Current perspectives on the diagnosis and management of acute transverse myelitis. Expert Rev Neurother. 2023 Apr; 23 (4):389-411 Epub 2023 Apr 07 View PubMed Cacciaguerra L, Morris P, Tobin WO, Chen JJ, Banks SA, Elsbernd P, Redenbaugh V, Tillema JM, Montini F, Sechi E, Lopez-Chiriboga AS, Zalewski N, Guo Y, Rocca MA, Filippi M, Pittock SJ, Lucchinetti CF, Flanagan EP. Tumefactive Demyelination in MOG Ab-Associated Disease, Multiple Sclerosis, and AQP-4-IgG-Positive Neuromyelitis Optica Spectrum Disorder. 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Mult Scler Relat Disord. 2018 Jan; 19:115-117 Epub 2017 Nov 16 View PubMed Dubey D, Pittock SJ, Kelly CR, McKeon A, Lopez-Chiriboga AS, Lennon VA, Gadoth A, Smith CY, Bryant SC, Klein CJ, Aksamit AJ, Toledano M, Boeve BF, Tillema JM, Flanagan EP. Autoimmune encephalitis epidemiology and a comparison to infectious encephalitis. Ann Neurol. 2018 Jan; 83 (1):166-177 View PubMed Parks NE, Flanagan EP, Lucchinetti CF, Wingerchuk DM. NEDA treatment target? No evident disease activity as an actionable outcome in practice. J Neurol Sci. 2017 Dec 15; 383:31-34 Epub 2017 Oct 13 View PubMed Shosha E, Pittock SJ, Flanagan E, Weinshenker BG. Neuromyelitis optica spectrum disorders and pregnancy: Interactions and management. Mult Scler. 2017 Dec; 23 (14):1808-1817 View PubMed Dubey D, Forsthuber T, Flanagan EP, Pittock SJ, Stuve O. B-cell-targeted therapies in relapsing forms of MS. Neurol Neuroimmunol Neuroinflamm. 2017 Nov; 4 (6):e405 Epub 2017 Oct 23 View PubMed Ali F, Murray JA, Adams AC, Flanagan EP. Clinical Reasoning: A 54-year-old woman with dementia, myoclonus, and ataxia. Neurology. 2017 Jul 11; 89 (2):e7-e12 View PubMed Gadoth A, Pittock SJ, Dubey D, McKeon A, Britton JW, Schmeling JE, Smith A, Kotsenas AL, Watson RE, Lachance DH, Flanagan EP, Lennon VA, Klein CJ. Expanded phenotypes and outcomes among 256 LGI1/CASPR2-IgG-positive patients. Ann Neurol. 2017 Jul; 82 (1):79-92 View PubMed Gadoth A, Singh J, Britton JW, Flanagan EP, Pittock SJ. Dacrystic seizures-a cry for help. Neurol Neuroimmunol Neuroinflamm. 2017 Jul; 4 (4):e372 Epub 2017 June 16 View PubMed Savoldi F, Kaufmann TJ, Flanagan EP, Toledano M, Weinshenker BG. Elsberg syndrome: A rarely recognized cause of cauda equina syndrome and lower thoracic myelitis. Neurol Neuroimmunol Neuroinflamm. 2017 Jul; 4 (4):e355 Epub 2017 May 11 View PubMed Dubey D, Singh J, Britton JW, Pittock SJ, Flanagan EP, Lennon VA, Tillema JM, Wirrell E, Shin C, So E, Cascino GD, Wingerchuk DM, Hoerth MT, Shih JJ, Nickels KC, McKeon A. Predictive models in the diagnosis and treatment of autoimmune epilepsy. Epilepsia. 2017 Jul; 58 (7):1181-1189 Epub 2017 May 26 View PubMed Asgari N, Flanagan EP, Fujihara K, Kim HJ, Skejoe HP, Wuerfel J, Kuroda H, Kim SH, Maillart E, Marignier R, Pittock SJ, Paul F, Weinshenker BG. Disruption of the leptomeningeal blood barrier in neuromyelitis optica spectrum disorder. Neurol Neuroimmunol Neuroinflamm. 2017 Jul; 4 (4):e343 Epub 2017 Apr 21 View PubMed Lopez Chiriboga AS, Siegel JL, Tatum WO, Shih JJ, Flanagan EP. Striking basal ganglia imaging abnormalities in LGI1 ab faciobrachial dystonic seizures. Neurol Neuroimmunol Neuroinflamm. 2017 May; 4 (3):e336 Epub 2017 Mar 14 View PubMed Zalewski NL, Morris PP, Weinshenker BG, Lucchinetti CF, Guo Y, Pittock SJ, Krecke KN, Kaufmann TJ, Wingerchuk DM, Kumar N, Flanagan EP. Ring-enhancing spinal cord lesions in neuromyelitis optica spectrum disorders. J Neurol Neurosurg Psychiatry. 2017 Mar; 88 (3):218-225 Epub 2016 Dec 02 View PubMed Dubey D, Pittock SJ, Krecke KN, Flanagan EP. Association of Extension of Cervical Cord Lesion and Area Postrema Syndrome With Neuromyelitis Optica Spectrum Disorder. JAMA Neurol. 2017 Mar 1; 74 (3):359-361 View PubMed Flanagan EP, Hinson SR, Lennon VA, Fang B, Aksamit AJ, Morris PP, Basal E, Honorat JA, Alfugham NB, Linnoila JJ, Weinshenker BG, Pittock SJ, McKeon A. Glial fibrillary acidic protein immunoglobulin G as biomarker of autoimmune astrocytopathy: Analysis of 102 patients. Ann Neurol. 2017 Feb; 81 (2):298-309 View PubMed Lopez-Chiriboga AS, Huang JF, Flanagan EP, Cheshire WP Jr. Paroxysmal sneezing in NMOSD: Further evidence of the localization of the human sneeze center. Neurol Neuroimmunol Neuroinflamm. 2017 Jan; 4 (1):e303 Epub 2016 Oct 28 View PubMed Flanagan EP, Pittock SJ. Diagnosis and management of spinal cord emergencies. Handb Clin Neurol. 2017; 140:319-335 View PubMed Conway BL, Clarke MJ, Kaufmann TJ, Flanagan EP. Utility of extension views in spondylotic myelopathy mimicking transverse myelitis. Mult Scler Relat Disord. 2017 Jan; 11:62-64. View PubMed Keegan BM, Kaufmann TJ, Weinshenker BG, Kantarci OH, Schmalstieg WF, Paz Soldan MM, Flanagan EP. Progressive solitary sclerosis: Gradual motor impairment from a single CNS demyelinating lesion. Neurology. 2016 Oct 18; 87 (16):1713-1719 Epub 2016 Sept 16 View PubMed Zalewski NL, Krecke KN, Weinshenker BG, Aksamit AJ, Conway BL, McKeon A, Flanagan EP. Central canal enhancement and the trident sign in spinal cord sarcoidosis. Neurology. 2016 Aug 16; 87 (7):743-4 View PubMed Flanagan EP, Cabre P, Weinshenker BG, Sauver JS, St Sauver J, Jacobson DJ, Majed M, Lennon VA, Lucchinetti CF, McKeon A, Matiello M, Kale N, Wingerchuk DM, Mandrekar J, Sagen JA, Fryer JP, Robinson AB, Pittock SJ. Epidemiology of aquaporin-4 autoimmunity and neuromyelitis optica spectrum. Ann Neurol. 2016 May; 79 (5):775-783 Epub 2016 Apr 04 View PubMed Flanagan EP, Kaufmann TJ, Krecke KN, Aksamit AJ, Pittock SJ, Keegan BM, Giannini C, Weinshenker BG. Discriminating long myelitis of neuromyelitis optica from sarcoidosis. Ann Neurol. 2016 Mar; 79 (3):437-47 Epub 2016 Feb 12 View PubMed Flanagan EP, Duffy JR, Whitwell JL, Vemuri P, Dickson DW, Josephs KA. Mixed tau and TDP-43 pathology in a patient with unclassifiable primary progressive aphasia. Neurocase. 2016; 22 (1):55-9 Epub 2015 May 01 View PubMed Flanagan EP. Autoimmune myelopathies. Handb Clin Neurol. 2016; 133:327-51 View PubMed Flanagan EP, Drubach DA, Boeve BF. Autoimmune dementia and encephalopathy. Handb Clin Neurol. 2016; 133:247-67 View PubMed McCarter SJ, Tippmann-Peikert M, Sandness DJ, Flanagan EP, Kantarci K, Boeve BF, Silber MH, St Louis EK. Neuroimaging-evident lesional pathology associated with REM sleep behavior disorder. Sleep Med. 2015 Dec; 16: (12)1502-10. View PubMed Flanagan EP, Kotsenas AL, Britton JW, McKeon A, Watson RE, Klein CJ, Boeve BF, Lowe V, Ahlskog JE, Shin C, Boes CJ, Crum BA, Laughlin RS, Pittock SJ. Basal ganglia T1 hyperintensity in LGI1-autoantibody faciobrachial dystonic seizures. Neurol Neuroimmunol Neuroinflamm. 2015 Dec; 2 (6):e161 Epub 2015 Oct 01 View PubMed Jones AL, Flanagan EP, Pittock SJ, Mandrekar JN, Eggers SD, Ahlskog JE, McKeon A. Responses to and Outcomes of Treatment of Autoimmune Cerebellar Ataxia in Adults. JAMA Neurol. 2015 Nov; 72 (11):1304-12 View PubMed Pichler MR, Flanagan EP, Aksamit AJ, Leavitt JA, Salomao DR, Keegan BM. Conjunctival biopsy to diagnose neurosarcoidosis in patients with inflammatory nervous system disease of unknown etiology. Neurol Clin Pract. 2015 Jun; 5 (3):216-223 View PubMed Flanagan EP, Weinshenker BG, Krecke KN, Pittock SJ. Asymptomatic myelitis in neuromyelitis optica and autoimmune aquaporin-4 channelopathy. Neurol Clin Pract. 2015 Apr; 5 (2):175-177 View PubMed Flanagan EP, Baker MC, Perkerson RB, Duffy JR, Strand EA, Whitwell JL, Machulda MM, Rademakers R, Josephs KA. Dominant frontotemporal dementia mutations in 140 cases of primary progressive aphasia and speech apraxia. Dement Geriatr Cogn Disord. 2015; 39 (5-6):281-6 Epub 2015 Feb 28 View PubMed Flanagan EP, Weinshenker BG, Krecke KN, Lennon VA, Lucchinetti CF, McKeon A, Wingerchuk DM, Shuster EA, Jiao Y, Horta ES, Pittock SJ. Short myelitis lesions in aquaporin-4-IgG-positive neuromyelitis optica spectrum disorders. JAMA Neurol. 2015 Jan; 72 (1):81-7 View PubMed Flanagan EP, Saito YA, Lennon VA, McKeon A, Fealey RD, Szarka LA, Murray JA, Foxx-Orenstein AE, Fox JC, Pittock SJ. Immunotherapy trial as diagnostic test in evaluating patients with presumed autoimmune gastrointestinal dysmotility. Neurogastroenterol Motil. 2014 Sep; 26 (9):1285-97 Epub 2014 July 20 View PubMed Flanagan EP, Weinshenker BG. Neuromyelitis optica spectrum disorders. Curr Neurol Neurosci Rep. 2014 Sep; 14 (9):483 View PubMed Flanagan EP, Krecke KN, Marsh RW, Giannini C, Keegan BM, Weinshenker BG. Specific pattern of gadolinium enhancement in spondylotic myelopathy. Ann Neurol. 2014 Jul; 76: (1)54-65. View PubMed Flanagan EP, Leep Hunderfund AN, Kumar N, Murray JA, Krecke KN, Katz BS, Pittock SJ. Clinical reasoning: a 55-year-old man with weight loss, ataxia, and foot drop. Neurology. 2014 Jun 17; 82 (24):e214-9 View PubMed Flanagan EP, Knopman DS, Keegan BM. Dementia in MS complicated by coexistent Alzheimer disease: Diagnosis premortem and postmortem. Neurol Clin Pract. 2014 Jun; 4 (3):226-230 View PubMed Flanagan EP, McKeon A, Weinshenker BG. Anterior spinal artery infarction causing man-in-the-barrel syndrome. Neurol Clin Pract. 2014 Jun; 4 (3):268-269 View PubMed Groarke PJ, Kelly JC, Flanagan E, et al. The forgotten foot - An assessment of foot and ankle radiograph pathology in final year medical students. Surgeon. 2014 Apr 27. Flanagan EP, Rabinstein AA, Kumar N, Schroeder K, Kantarci OH. Fulminant cerebellitis with radiological recurrence in an adult patient with Crohn's disease. J Neurol Sci. 2014 Jan 15; 336: (1-2)247-50. View PubMed Child ND, Braksick SA, Flanagan EP, Keegan BM, Giannini C, Kantarci OH. Amyloid-beta-related angiitis presenting as a uveomeningeal syndrome. Neurology. 2013 Nov 12; 81: (20)1796-8. View PubMed Taylor JW, Flanagan EP, O'Neill BP, Siegal T, Omuro A, Deangelis L, Baehring J, Nishikawa R, Pinto F, Chamberlain M, Hoang-Xuan K, Gonzalez-Aguilar A, Batchelor T, Blay JY, Korfel A, Betensky RA, Lopes MB, Schiff D. Primary leptomeningeal lymphoma: International Primary CNS Lymphoma Collaborative Group report. Neurology. 2013 Nov 5; 81 (19):1690-6 Epub 2013 Oct 09 View PubMed Flanagan EP, Hunt CH, Lowe V, Mandrekar J, Pittock SJ, O'Neill BP, Keegan BM. [(18)F]-fluorodeoxyglucose-positron emission tomography in patients with active myelopathy. Mayo Clin Proc. 2013 Nov; 88 (11):1204-12 View PubMed Flanagan EP, Aksamit AJ, Kumar N, Morparia NP, Keegan BM, Weinshenker BG. Simultaneous PML-IRIS and myelitis in a patient with neuromyelitis optica spectrum disorder. Neurol Clin Pract. 2013 Oct; 3 (5):448-451 View PubMed Flanagan EP, Kaufmann TJ, Keegan BM. Sjogren's syndrome with trigeminal neuropathy: motor involvement. Pract Neurol. 2013 Oct; 13(5):340-2. Epub 2013 May 23. View PubMed Flanagan EP, Marsh RW, Weinshenker BG. Teaching neuroimages: "pancake-like" gadolinium enhancement suggests compressive myelopathy due to spondylosis. Neurology. 2013 May 21; 80(21):e229. View PubMed Flanagan EP, Keegan BM. Paraneoplastic myelopathy. Neurol Clin. 2013 Feb; 31 (1):307-18 View PubMed Flanagan EP, Gavrilova RH, Boeve BF, Kumar N, Jelsing EJ, Silber MH. Adult-onset autosomal dominant leukodystrophy presenting with REM sleep behavior disorder. Neurology. 2013 Jan 1; 80(1):118-20. Epub 2012 Dec 12. View PubMed Flanagan EP, Sandroni P, Pittock SJ, Inwards DJ, Jones LK Jr. Paraneoplastic lower motor neuronopathy associated with Hodgkin lymphoma. Muscle Nerve. 2012 Nov; 46(5):823-7. View PubMed Groarke P, Kelly J, Flanagan E, et al. A pain in the neck--medical student attitudes to the Orthopaedic spine. Ir Med J. 2012 Sep; 105(8):274-5. Flanagan EP, O'Neill BP, Habermann TM, Porter AB, Keegan BM. Secondary intramedullary spinal cord non-Hodgkin's lymphoma. J Neurooncol. 2012 May; 107 (3):575-80 Epub 2011 Dec 22 View PubMed Flanagan EP, Hunderfund AL, Giannini C, Meissner I. Addition of magnetic resonance imaging to computed tomography and sensitivity to blood in pituitary apoplexy. Arch Neurol. 2011 Oct; 68: (10)1336-7. View PubMed Flanagan EP, O'Neill BP, Porter AB, Lanzino G, Haberman TM, Keegan BM. Primary intramedullary spinal cord lymphoma. Neurology. 2011 Aug 23; 77 (8):784-91 Epub 2011 Aug 10 View PubMed Flanagan EP, Lennon VA, Pittock SJ. Autoimmune myelopathies. Continuum.2011 Aug;17:(4):776-99. Flanagan EP, McKeon A, Lennon VA, Kearns J, Weinshenker BG, Krecke KN, Matiello M, Keegan BM, Mokri B, Aksamit AJ, Pittock SJ. Paraneoplastic isolated myelopathy: clinical course and neuroimaging clues. Neurology. 2011 Jun 14; 76(24):2089-95. View PubMed Flanagan EP, Caselli RJ. Autoimmune encephalopathy. Semin Neurol. 2011 Apr; 31 (2):144-57 Epub 2011 May 17 View PubMed Kelly JC, Groarke PJ, Flanagan E, et al. Foot and ankle surgery - The Achilles heel of medical students and doctors. The Foot 8. 2010 Dec. Flanagan EP, McKeon A, Lennon VA, Boeve BF, Trenerry MR, Tan KM, Drubach DA, Josephs KA, Britton JW, Mandrekar JN, Lowe V, Parisi JE, Pittock SJ. Autoimmune dementia: clinical course and predictors of immunotherapy response. Mayo Clin Proc. 2010 Oct; 85 (10):881-97 View PubMed Zinchuk AV, Flanagan EP, Tubridy NJ, et al. Attitudes of US medical trainees towards neurology education: "Neurophobia" - a global issue. BMC Medical Education Jun 23;. 2010; 10:49. Flanagan E, Walsh C, Tubridy N. 'Neurophobia' - Attitudes of medical students and doctors in Ireland to neurological teaching. The European Journal of Neurology.2007;14:1109-12. PST-20216465 Home Publications