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Mirek Fatyga, Ph.D.

  1. Radiologist
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Publications

  1. Hu J, Fatyga M, Liu W, Schild SE, Wong WW, Vora SA, Li J. Radiotherapy toxicity prediction using knowledge-constrained generalized linear model. IISE Trans Healthc Syst Eng. 2024; 14 (2):130-140 Epub 2023 July 07
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  2. Ding Y, Holmes J, Li B, Vargas CE, Vora SA, Wong WW, Fatyga M, Foote RL, Patel SH, Liu W. Patient-Specific 3D CT Images Reconstruction from 2D KV Images Via Vision Transformer-Based Deep-Learning. Int J Radiat Oncol Biol Phys. 2023 Oct 1; 117 (2S):e660
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  3. Hu J, Schild SE, Liu W, Li J, Fatyga M. Improving Dose Volume Histogram (DVH) Based Analysis of Clinical Outcomes Using Modern Statistical Techniques: A Systematic Answer to Multiple Comparisons Concerns. Int J Radiat Oncol Biol Phys. 2023 Oct 1; 117 (2S):S20
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  4. Kang Y, Bues M, Halyard MY, McGee LA, Vern-Gross TZ, Wong WW, Keole SR, Vargas C, James SE, Ahmed SK, Archuleta JP, Ridgway AK, Lara PR, Fatyga M. Dose delivery reproducibility for PBS proton treatment of breast cancer patients with and without mask immobilization. Radiat Oncol. 2023 Sep 22; 18 (1):157 Epub 2023 Sept 22
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  5. Shan J, Feng H, Morales DH, Patel SH, Wong WW, Fatyga M, Bues M, Schild SE, Foote RL, Liu W. Virtual particle Monte Carlo: A new concept to avoid simulating secondary particles in proton therapy dose calculation. Med Phys. 2022 Oct; 49 (10):6666-6683 Epub 2022 Aug 22
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  6. Laughlin BS, Anderson JD, Gagneur JD, Chungbin SJ, Bues M, Hobbis D, Fatyga M, Korte SM, Carroll SE, Vora S, Sio TT, Wong WW, Keole SR, Rong Y. Implementation of Photon Treatment Back-up Workflow at a High-Volume Proton Center: Safety, Quality, and Patient Considerations. Pract Radiat Oncol. 2022 Sep-Oct; 12 (5):e453-e459 Epub 2022 Mar 07
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  7. Yang Y, Patel SH, Bridhikitti J, Wong WW, Halyard MY, McGee LA, Rwigema JM, Schild SE, Vora SA, Liu T, Bues M, Fatyga M, Foote RL, Liu W. Exploratory study of seed spots analysis to characterize dose and linear-energy-transfer effect in adverse event initialization of pencil-beam-scanning proton therapy. Med Phys. 2022 Sep; 49 (9):6237-6252 Epub 2022 July 21
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  8. Penoncello GP, Gagneur JD, Vora SA, Yu NY, Fatyga M, Mrugala MM, Bendok BR, Rong Y. Comprehensive Commissioning and Clinical Implementation of GammaTiles STaRT for Intracranial Brain Cancer. Adv Radiat Oncol. 2022 Jul-Aug; 7 (4):100910 Epub 2022 Feb 05
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  9. Feng H, Patel SH, Wong WW, Younkin JE, Penoncello GP, Morales DH, Stoker JB, Robertson DG, Fatyga M, Bues M, Schild SE, Foote RL, Liu W. GPU-accelerated Monte Carlo-based online adaptive proton therapy: A feasibility study. Med Phys. 2022 Jun; 49 (6):3550-3563 Epub 2022 Apr 27
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  10. Yang Y, Muller OM, Shiraishi S, Harper M, Amundson AC, Wong WW, McGee LA, Rwigema JM, Schild SE, Bues M, Fatyga M, Anderson JD, Patel SH, Foote RL, Liu W. Empirical Relative Biological Effectiveness (RBE) for Mandible Osteoradionecrosis (ORN) in Head and Neck Cancer Patients Treated With Pencil-Beam-Scanning Proton Therapy (PBSPT): A Retrospective, Case-Matched Cohort Study. Front Oncol. 2022; 12:843175 Epub 2022 Mar 03
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  11. Feng H, Shan J, Anderson JD, Wong WW, Schild SE, Foote RL, Patrick CL, Tinnon KB, Fatyga M, Bues M, Patel SH, Liu W. Per-voxel constraints to minimize hot spots in linear energy transfer-guided robust optimization for base of skull head and neck cancer patients in IMPT. Med Phys. 2022 Jan; 49 (1):632-647 Epub 2021 Dec 10
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  12. Anderson J, Hu J, Li J, Daniels TB, Schild SE, Fatyga M. Association Between Radiation Heart Dose and Overall Survival in Lung Stereotactic Body Radiation Therapy. Int J Radiat Oncol Biol Phys. 2021 Nov 1; 111 (3S):e427-e428
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  13. Niska JR, Hu J, Li J, Herman MG, Thorpe CS, Schild SE, Fatyga M. Using Novel Statistical Techniques to Accurately Determine the Predictive Dose Range in a Study of Overall Survival after Definitive Radiotherapy for Stage III Non-Small Cell Lung Cancer in Association with Heart Dose. J Cancer Ther. 2021 Sep; 12 (9):505-529 Epub 2021 Sept 29
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  14. Younkin JE, Morales DH, Shen J, Ding X, Stoker JB, Yu NY, Sio TT, Daniels TB, Bues M, Fatyga M, Schild SE, Liu W. Technical Note: Multiple energy extraction techniques for synchrotron-based proton delivery systems may exacerbate motion interplay effects in lung cancer treatments. Med Phys. 2021 Sep; 48 (9):4812-4823 Epub 2021 July 29
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  15. Feng H, Shan J, Ashman JB, Rule WG, Bhangoo RS, Yu NY, Chiang J, Fatyga M, Wong WW, Schild SE, Sio TT, Liu W. Technical Note: 4D robust optimization in small spot intensity-modulated proton therapy (IMPT) for distal esophageal carcinoma. Med Phys. 2021 Aug; 48 (8):4636-4647 Epub 2021 June 24
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  16. Yang Y, Vargas CE, Bhangoo RS, Wong WW, Schild SE, Daniels TB, Keole SR, Rwigema JM, Glass JL, Shen J, DeWees TA, Liu T, Bues M, Fatyga M, Liu W. Exploratory Investigation of Dose-Linear Energy Transfer (LET) Volume Histogram (DLVH) for Adverse Events Study in Intensity Modulated Proton Therapy (IMPT). Int J Radiat Oncol Biol Phys. 2021 Jul 15; 110 (4):1189-1199 Epub 2021 Feb 20
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  17. Anderson JD, Hu J, Li J, Schild SE, Fatyga M. Impact of Cardiac Dose on Overall Survival in Lung Stereotactic Body Radiotherapy (SBRT) Compared to Conventionally Fractionated Radiotherapy for Locally Advanced Non-Small Cell Lung Cancer (LA-NSCLC). J Cancer Ther. 2021 Jul; 12 (7):409-423
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  18. Craft DF, Lentz J, Armstrong M, Foster M, Gagneur J, Harrington D, Schild SE, Fatyga M. Three-Dimensionally Printed On-Skin Radiation Shields Using High-Density Filament. Pract Radiat Oncol. 2020 Nov - Dec; 10 (6):e543-e550 Epub 2020 May 13
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  19. Shan J, Yang Y, Schild SE, Daniels TB, Wong WW, Fatyga M, Bues M, Sio TT, Liu W. Intensity-modulated proton therapy (IMPT) interplay effect evaluation of asymmetric breathing with simultaneous uncertainty considerations in patients with non-small cell lung cancer. Med Phys. 2020 Nov; 47 (11):5428-5440 Epub 2020 Oct 13
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  20. Feng H, Sio TT, Rule WG, Bhangoo RS, Lara P, Patrick CL, Korte S, Fatyga M, Wong WW, Schild SE, Ashman JB, Liu W. Beam angle comparison for distal esophageal carcinoma patients treated with intensity-modulated proton therapy. J Appl Clin Med Phys. 2020 Nov; 21 (11):141-152 Epub 2020 Oct 15
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  21. Deng W, Younkin JE, Souris K, Huang S, Augustine K, Fatyga M, Ding X, Cohilis M, Bues M, Shan J, Stoker J, Lin L, Shen J, Liu W. Technical Note: Integrating an open source Monte Carlo code "MCsquare" for clinical use in intensity-modulated proton therapy. Med Phys. 2020 Jun; 47 (6):2558-2574 Epub 2020 Apr 13
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  22. Liu X, Fatyga M, Schild SE, Li J. Detecting spatial susceptibility to cardiac toxicity of radiation therapy for lung cancer. IISE Trans Healthc Syst Eng. 2020; 10 (4):243-250 Epub 2020 July 22
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  23. Kang Y, Shen J, Liu W, Taylor PA, Mehrens HS, Ding X, Hu Y, Tryggestad E, Keole SR, Schild SE, Wong WW, Fatyga M, Bues M. Impact of planned dose reporting methods on Gamma pass rates for IROC lung and liver motion phantoms treated with pencil beam scanning protons. Radiat Oncol. 2019 Jun 17; 14 (1):108 Epub 2019 June 17
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  24. Liu X, Fatyga M, Wu T, Li J. Integration of biological and statistical models toward personalized radiation therapy of cancer Iise Transactions. 2019; 51(3):311-21. Epub 1900 Jan 01.
  25. Hernandez Morales D, Shan J, Liu W, Augustine KE, Bues M, Davis MJ, Fatyga M, Johnson JE, Mundy DW, Shen J, Younkin JE, Stoker JB. Automation of routine elements for spot-scanning proton patient-specific quality assurance. Med Phys. 2019 Jan; 46 (1):5-14 Epub 2018 Nov 20
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  26. Whitaker TJ, Mayo CS, Ma DJ, Haddock MG, Miller RC, Corbin KS, Neben-Wittich M, Leenstra JL, Laack NN, Fatyga M, Schild SE, Vargas CE, Tzou KS, Hadley AR, Buskirk SJ, Foote RL. Data collection of patient outcomes: one institution's experience. J Radiat Res. 2018 Mar 1; 59 (suppl_1):i19-i24
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  27. Liu X, Li J, Schild SE, Li J, Schild MH, Wong W, Vora S, Herman MG, Fatyga M. Modeling of Acute Rectal Toxicity to Compare Two Patient Positioning Methods for Prostate Cancer Radiotherapy: Can Toxicity Modeling be Used for Quality Assurance? OMICS J Radiol. 2018; 7 (5) Epub 2018 Dec 03
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  28. Liu X, Li J, Schild SE, Schild MH, Wong W, Vora S, Herman MG, Fatyga M. Statins and Metformin Use Is Associated with Lower PSA Levels in Prostate Cancer Patients Presenting for Radiation Therapy. J Cancer Ther. 2017 Feb; 8 (2):73-85 Epub 2017 Feb 06
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  29. Mayo CS, Pisansky TM, Petersen IA, Yan ES, Davis BJ, Stafford SL, Garces YI, Miller RC, Martenson JA, Mutter RW, Choo R, Hallemeier CL, Laack NN, Ma DJ, Olivier KR, Keole SR, Fatyga M, Foote RL, Haddock MG. Establishment of practice standards in nomenclature and prescription to enable construction of software and databases for knowledge-based practice review. Pract Radiat Oncol. 2016 Jul-Aug; 6 (4):e117-e126 Epub 2016 Jan 26
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  30. Liu X, Li J, Wu T, Schild SE, Schild MH, Wong W, Vora S, Fatyga M. Patient Specific Characteristics Are an Important Factor That Determines the Risk of Acute Grade >/= 2 Rectal Toxicity in Patients Treated for Prostate Cancer with IMRT and Daily Image Guidance Based on Implanted Gold Markers. OMICS J Radiol. 2016 Jun; 5 (3) Epub 2016 June 13
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  31. Augustine KE, Walsh TJ, Beltran CJ, Stoker JB, Mundy DW, Parry MD, Bues M, Fatyga M. Spot scanning proton therapy plan assessment: Design and development of a dose verification application for use in routine clinical practice Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2016; 9783:97835S.
  32. Shen J, Liu W, Anand A, Stoker JB, Ding X, Fatyga M, Herman MG, Bues M. Impact of range shifter material on proton pencil beam spot characteristics. Med Phys. 2015 Mar; 42 (3):1335-40
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  33. Liu W, Liao Z, Schild SE, Liu Z, Li H, Li Y, Park PC, Li X, Stoker J, Shen J, Keole S, Anand A, Fatyga M, Dong L, Sahoo N, Vora S, Wong W, Zhu XR, Bues M, Mohan R. Impact of respiratory motion on worst-case scenario optimized intensity modulated proton therapy for lung cancers. Pract Radiat Oncol. 2015 Mar-Apr; 5 (2):e77-86 Epub 2014 Sept 11
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  34. Fatyga M, Dogan N, Weiss E, Sleeman WC IV, Zhang B, Lehman WJ, Williamson JF, Wijesooriya K, Christensen GE. A voxel-by-voxel comparison of deformable vector fields obtained by three deformable image registration algorithms applied to 4DCT lung studies. Frontiers in Oncology. 2015; 5(Feb):17.
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  35. Weiss E, Fatyga M, Wu Y, Dogan N, Balik S, Sleeman W 4th, Hugo G. Dose escalation for locally advanced lung cancer using adaptive radiation therapy with simultaneous integrated volume-adapted boost. Int J Radiat Oncol Biol Phys. 2013 Jul 1; 86(3):414-9. Epub 2013 Mar 21.
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  36. Balik S, Weiss E, Jan N, Roman N, Sleeman WC, Fatyga M, Christensen GE, Zhang C, Murphy MJ, Lu J, Keall P, Williamson JF, Hugo GD. Evaluation of 4-dimensional computed tomography to 4-dimensional cone-beam computed tomography deformable image registration for lung cancer adaptive radiation therapy. Int J Radiat Oncol Biol Phys. 2013 Jun 1; 86(2):372-9. Epub 2013 Feb 22.
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  37. Schutzer ME, Song S, Fatyga M, Asher DA, Sleeman W, Dogan N. Quantitative assessment of volumetric changes using fan beam and cone beam computed tomography during head and neck image guided radiotherapy. Pract Radiat Oncol. 2013 Apr-Jun; 3: (2 Suppl 1)S34.
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  38. Fatyga M, Zhang B, Sleeman WC IV. Designing and implementing a computing framework for image guided adaptive radiation therapy research. Computing in Science and Engineering. 2012 Jul/Aug; 14(4):57-68.
  39. Mihaylov IB, Fatyga M, Bzdusek K, Gardner K, Moros EG. Biological optimization in volumetric modulated arc radiotherapy for prostate carcinoma. Int J Radiat Oncol Biol Phys. 2012 Mar 1; 82(3):1292-8. Epub 2011 May 11.
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  40. Mihaylov IB, Fatyga M, Moros EG, Penagaricano J, Lerma FA. Lung dose for minimally moving thoracic lesions treated with respiration gating. Int J Radiat Oncol Biol Phys. 2010 May 1; 77(1):285-91. Epub 2010 Jan 25.
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  41. Fatyga M, Williamson JF, Dogan N, Todor D, Siebers JV, George R, Barani I, Hagan M. A comparison of HDR brachytherapy and IMRT techniques for dose escalation in prostate cancer: a radiobiological modeling study. Med Phys. 2009 Sep; 36(9):3995-4006.
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  42. Suh Y, Weiss E, Zhong H, Fatyga M, Siebers JV, Keall PJ. A deliverable four-dimensional intensity-modulated radiation therapy-planning method for dynamic multileaf collimator tumor tracking delivery. Int J Radiat Oncol Biol Phys. 2008 Aug 1; 71(5):1526-36.
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  43. Murphy MJ, Wei Z, Fatyga M, Williamson J, Anscher M, Wallace T, Weiss E. How does CT image noise affect 3D deformable image registration for image-guided radiotherapy planning? Med Phys. 2008 Mar; 35(3):1145-53.
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  44. Mihaylov IB, Lerma FA, Fatyga M, Siebers JV. Quantification of the impact of MLC modeling and tissue heterogeneities on dynamic IMRT dose calculations. Med Phys. 2007 Apr; 34(4):1244-52.
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  45. Dogan N, Siebers JV, Keall PJ, Lerma F, Wu Y, Fatyga M, Williamson JF, Schmidt-Ullrich RK. Improving IMRT dose accuracy via deliverable Monte Carlo optimization for the treatment of head and neck cancer patients. Med Phys. 2006 Nov; 33(11):4033-43.
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  46. Melian E, Fatyga M, Lam P, Steinberg M, Reddy SP, Petruzzelli GJ, Glasgow GP. Effect of metal reconstruction plates on cobalt-60 dose distribution: a predictive formula and clinical implications. Int J Radiat Oncol Biol Phys. 1999 Jun 1; 44(3):725-30.
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  47. Abachi S, D0 Collaboration. Inclusive muon and b quark production cross section in p-pbar collisions at sqrt(s)=1.8TeV. Phys Rev Lett. 1995; 74:3548-52.
  48. Abachi S, D0 Collaboration. Search for W boson pair production in p-pbar collosions at sqrt(s)=1.8TeV. Phys Rev Lett. 1995; 75:1023-27.
  49. Abachi S, D0 Collaboration. Measurement of the WW-gamma gauge boson couplings in p-pbar collosions at sqrt(s)=1.8TeV. Phys Rev Lett. 1995; 75:1034-39.
  50. Abachi S, D0 Collaboration. Search for squarks and gluinos in p-pbar collosions at sqrt(s)=1.8TeV. Phys Rev Lett. 1995; 75:618-23.
  51. Abachi S, D0 Collaboration. Observation of the top quark in p-pbar collisions at sqrt(s) = 1.8TeV. Phys Rev Lett. 1994; 72:2138-42.
  52. Abachi S, D0 Collaboration. First generation leptoquark search in p-pbar collosions at sqrt(s)=1.8TeV. Phys Rev Lett. 1994; 72:965.
  53. Abachi S, D0 Collaboration. Rapidity gaps between jets in p-pbar collosions at sqrt(s)=1.8TeV. Fermilab-Pub. 1994; 005-E.
  54. Abachi S, D0 Collaboration. The D0 detector. NIM. 1994; A338:185-223.
  55. Barrette J, E814 Collaboration. Antiproton production in relativistic Si-nucleus collisions. Phys Rev Lett. 1993; 70:1763.
  56. Abachi S, D0 Collaboration. Beam tests of the D0 uranium liquid argon end calorimeters. NIM. 1993; A324:53-76.
  57. Barrette J, E814 Collaboration. Forward baryons in relativistic nucleus-nucleus collisions. Phys Rev. 1992; C45:819-.
  58. Barrette J, E814 Collaboration. Excitation energy distribution of relativistic 28Si in electromagnetic dissociation into p+27Al. Phys Rev. 1992; C45:2427.
  59. Barrette J, E814 Collaboration. Charged particle multiplicity in 28Si+Al,Cu, and Pb Reactions at Elab=14.6Gev/nucleon. Phys Rev. 1992; C46:312.
  60. Barrette J, E814 Collaboration. Electromagnetic dissociation of 28Si at E/A=14.6GeV by nucleon emission. Phys Rev. 1990; C41:1512.
  61. Barrette J, E814 Collaboration. Energy flow and stopping in relativistic heavy ion collisions at E/A=14.6GeV. Phys Rev Lett. 1990; 64:11-.
  62. Barrette J, E814 Collaboration. Search for strange quark matter in high energy heavy ion collisions. Phys Lett. 1990; B252:550-.
  63. Skulski W, Jastrzebski J, Singh PP, Chen Q, Fatyga M. Limitations to the linear momentum transfer in 4He+59Co collisions. Phys Rev. 1990; C41:2605.
  64. Skulski W, Fatyga M, Kwiatkowski K, Karwowski HJ, Woo LW, Viola VE. Emission of energetic protons at backward angles in central collisions. Phys Lett. 1989; B218:7.
  65. Skulski W, Fatyga M, Karwowski HJ, Kwiatkowski K, Viola VE, Hicks K, Ristinen R. Linear momentum transfer in the reaction of 64-269MeV 3He with 238U. Phys Rev. 1989; C40:1279.
  66. Fatyga M, Makowiecki D, Llope WJ. Fast Monte Carlo simulation of a lateral shower spread in a segmented U/Cu/Scint calorimeter. A comparison with data. NIM. 1989; A284:323.
  67. Barrette J, E814 Collaboration. Transverse energy distributions in Si-nucleus collisons at 10GeV/nucleus. Z Phys. 1988; C38:45-.
  68. Fatyga M, Byrd R, Kwiatkowski K, Karwowski HJ, Wilson W, Viola VE, Stith K, Jastrzebski J, Skulski W. Properties of intermediate mass fragments emission source in the 270MeV 3He+232Th reaction. Phys Lett. 1987; B185:321.
  69. Fatyga M, Karwowski HJ, Kwiatkowski K, Nowicki L, Viola VE, Hicks KH. Light particle emission and linear momentum transfer in 150MeV 6Li+238U reaction. Phys Rev. 1987; C35:568.
  70. Fatyga M, Kwiatkowski K, Viola VE, Chitwood CB, Fields DJ, Gelbke CK, Lynch WG, Pochodzalla J, Tsang MB. Properties of intermediate mass fragments emission source in 14N+232Th Reaction. Phys Rev Lett. 1987; 58:2527.
  71. Pickar MA, Karwowski HJ, Brown JD, Hall JR, Hugi M, Pollock RE, Cupps VR, Fatyga M, Bacher AD. Proton radiative capture by Deuterium between 100 and 200MeV. Phys Rev. 1987; C35:37.
  72. Kwiatkowski K, Bashkin J, Karwowski HJ, Fatyga M, Viola VE. Intermediate mass fragment production in the reaction of 200 MeV 3He with natural Ag. Phys Lett. 1986; B171:41.
  73. Jastrzebski J, Singh PP, Mroz T, Karwowski HJ, Vigdor SE, Fatyga M. Interaction of 5-50MeV/nucleon 3He and 4He with 59Co. Phys Rev. 1986; C34:60.
  74. Schott W, Segel RE, Huchler S, Wagner W, Homolka J, Wilhelm W, Kienle P, Huber M, Rehm K, Saber M, Bear K, Bent R, Fatyga M, Pollock R. Observation of the 12C(3He,pi+)15N reaction near threshold using recoil detection. Phys Rev. 1986; C34:1406.
  75. Homolka J, Schott W, Wagner W, Wilhelm W, Bent RD, Fatyga M, Pollock RE, Saber M, Segel RE, Kienle P. Measurement of the 12C(3He,pi+)15N reaction cross section near threshold. Phys Rev. 1986; C38:2686.
  76. Fatyga M, Kwiatkowski K, Viola VE, Chitwood CB, Fields DJ, Gelbke CK, Lynch WG, Pochodzalla J, Tsang MB, Blann M. Evolution of nucleus-nucleus collision mechanism from the barrier to beyond the fermi energy. Phys Rev Lett. 1985; 55:1376.
  77. Fatyga M, Kwiatkowski K, Karwowski HJ, Woo LW, Viola VE. Linear momentum transfer in 40-150MeV proton induced reactions with 238U. Phys Rev. 1985; C32:1496.
  78. Jastrzebski J, Singh PP, Mroz T, Karwowski HJ, Vigdor SE, Fatyga M. Momentum transfer in 30-200Mev 4He induced reactions with 59Co. Phys Lett. 1984; C136:153.
  79. Tsang MB, Klesch DR, Chitwood CB, Fields DJ, Gelbke CK, Lynch WG, Utsunomiya H, Kwiatkowski K, Viola VE, Fatyga M. Limitations on linear momentum transfer in 14 N induced reactions on 238U at E/A=15,20,25,30MeV. Phys Lett. 1984; B134:169.
PST-20226788