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Dong Chen, M.D., Ph.D.

  1. Pathologist
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Publications

  1. Pierre C, Alcorn KW, Chen D, Fesler J, Landis D, Litvack ZN, Konkle BA, Hegerova L. Neurosurgical bleeding in platelet storage pool disorder: a case report. Platelets. 2024 Dec; 35 (1):2380374 Epub 2024 July 23
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  2. Navarro SM, Ashrani A, Park MS, Chen D. Histological Findings of ETosis in Hermansky-Pudlak Syndrome with Pulmonary Fibrosis: A Follow-Up Case Report. J Chest Surg. 2024 Oct 22 [Epub ahead of print]
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  3. Zhang X, Ding Y, Li P, Bourgeois K, Rangan A, Herrick JL, Pardanani A, Chen D, Viswanatha D, He R, Zheng G. Null-type SH2B3 mutations are potential drivers in a subset of Ph-negative myeloproliferative neoplasms. Am J Hematol 2024 Sep; 99 (9):1841-1844 Epub 2024 June 25
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  4. Saadalla A, Chen D, Stuart M, Pruthi R, Heikal N, Snyder M, Ashrani A, Seheult J. The lupus anticoagulant titer is associated with elevated antiphosphatidylserine/prothrombin immunoglobulin-M isotype antibody levels. Int J Lab Hematol. 2024 Aug; 46 (4):695-704 Epub 2024 Feb 21
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  5. Li M, Baranwal A, Gurney M, Shah SN, Al-Kali A, Alkhateeb H, Foran J, Arana Yi C, Ongie L, Chen D, Mangaonkar A, McCullough K, Tefferi A, Lasho T, Finke C, Patnaik MM, Shah MV. The impact of cytotoxic therapy on the risk of progression and death in clonal cytopenia(s) of undetermined significance. Blood Adv. 2024 Jun 25; 8 (12):3130-3139
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  6. Olteanu H, Patnaik M, Koster MJ, Herrick JL, Chen D, He R, Viswanatha D, Warrington KJ, Go RS, Mangaonkar AA, Kourelis T, Hines A, Gibson SE, Peterson JF, Reichard KK. Comprehensive morphologic characterization of bone marrow biopsy findings in a large cohort of patients with VEXAS syndrome: A single-institution longitudinal study of 111 bone marrow samples from 52 patients. Am J Clin Pathol. 2024 Jun 3; 161 (6):609-624
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  7. Chen CP, Chen D. Type II mast cells in mast cell leukemia: Uncommon yet clinically significant. EJHaem. 2024 Apr; 5 (2):412-413 Epub 2024 Apr 08
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  8. Chen CP, Chen D. Genetic Testing for Inherited Platelet Disorders American Journal of Biomedical Science and Research. 3/6/2024; 21(5):576-579.
  9. Nelson Strande BJ, Sridharan M, Leger RR, Stuart MS, Tange JI, Navitska SD, Heikal N, Ashrani AA, Chen D, Seheult JN, Pruthi RK. Effect of residual platelets in frozen-thawed plasma on results of dilute Russell's viper venom time assay for lupus anticoagulant testing. Am J Clin Pathol. 2024 Mar 1; 161 (3):212-215
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  10. Chen D, Pruthi R. A Brief History of Hemostasis and Thrombosis at the Mayo Clinic. Semin Thromb Hemost. 2024 Feb; 50 (1):26-33 Epub 2023 Mar 20
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  11. Tefferi A, Pardanani A, Al-Kali A, Alkhateeb H, McCullough K, Patnaik M, Hogan WJ, Begna K, Elliott MA, Khera N, Palmer JM, Gangat N, Kelemen K, Orazi A, Chen D, Reichard KK. Mast cell cytomorphology and treatment outcome in mast cell leukemia. Am J Hematol 2024 Jan; 99 (1):E5-E8 Epub 2023 Sept 21
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  12. Pardanani A, Tefferi A, Al-Kali A, Patnaik M, Hogan WJ, Begna K, Elliott MA, Khera N, Palmer JM, Gangat N, Orazi A, Kelemen K, Reichard KK, Chen D. Reappraisal of mast cell leukemia based on a single institution review of 16 cases: Mast cell morphology determines clinical outcome. Am J Hematol 2024 Jan; 99 (1):E1-E4 Epub 2023 Sept 09
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  13. Tefferi A, Abdelmagid M, Al-Kali A, Patnaik M, Hogan WJ, Begna K, Gangat N, Orazi A, Chen D, Reichard KK, Pardanani A. Granularity in disease classification impacts survival prediction in advanced systemic mastocytosis: A single institution study of 329 informative cases. Am J Hematol. 2024 Jan; 99 (1):21-27 Epub 2023 Sept 29
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  14. Valencia Morales DJ, Klompas AM, Torbenson JM, Finney RE, Chen D, Stubbs JR, Nuttall GA. Cold platelet transfusion: The effects of a fluid warmer on platelet function. Transfusion. 2024 Jan; 64 (1):47-52 Epub 2023 Dec 19
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  15. Chen D, Pruthi RK. Platelet genetic testing by next-generation sequencing: A practical update. Int J Lab Hematol. 2023 Oct; 45 (5):630-642 Epub 2023 July 18
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  16. Pruthi RK, Chen D. The Use of Bypassing Treatment Strategies in Hemophilia and Their Effect on Laboratory Testing. Semin Thromb Hemost. 2023 Sep; 49 (6):651-660 Epub 2023 May 05
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  17. Saadalla A, Seheult J, Pruthi RK, Chen D. Von Willebrand Factor Multimer Analysis and Classification: A Comprehensive Review and Updates. Semin Thromb Hemost. 2023 Sep; 49 (6):580-591 Epub 2022 Sept 29
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  18. Kerber AA, Coon EA, Reichard KK, Chen D, Pongdee T, Chiarella SE. Systemic mastocytosis presenting with episodic rigors. J Allergy Clin Immunol Pract. 2023 Sep; 11 (9):2955-2956 Epub 2023 June 12
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  19. Kanack AJ, Athale J, Leger RR, Saadalla A, Heikal NM, Chen D, Garcia DA, Singh R, Pruthi RK, Padmanabhan A. "Autoimmune HIT" antibodies in diagnostic samples are a potential artifact and not associated with more severe outcomes. Blood Adv. 2023 Aug 22; 7 (16):4431-4434
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  20. Jess J, Yates B, Dulau-Florea A, Parker K, Inglefield J, Lichtenstein D, Schischlik F, Ongkeko M, Wang Y, Shahani S, Cullinane A, Smith H, Kane E, Little L, Chen D, Fry TJ, Shalabi H, Wang HW, Satpathy A, Lozier J, Shah NN. CD22 CAR T-cell associated hematologic toxicities, endothelial activation and relationship to neurotoxicity. J Immunother Cancer. 2023 Jun; 11 (6)
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  21. Bruehl FK, Osman MM, Chen D, Dalland JC. The new WHO and ICC classification systems for myelodysplastic syndromes and their impact on the clinical laboratory. J Hematop. 2023 Jun; 16 (2):65-71 Epub 2023 Mar 07
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  22. Shah MV, Tran ENH, Shah S, Chhetri R, Baranwal A, Ladon D, Shultz C, Al-Kali A, Brown AL, Chen D, Scott HS, Greipp P, Thomas D, Alkhateeb HB, Singhal D, Gangat N, Kumar S, Patnaik MM, Hahn CN, Kok CH, Tefferi A, Hiwase DK. TP53 mutation variant allele frequency of >/=10% is associated with poor prognosis in therapy-related myeloid neoplasms. Blood Cancer J. 2023 Apr 11; 13 (1):51
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  23. Saadalla A, Stuart M, Ashrani A, Pruthi R, Morava E, Chen D, Seheult J. In special coagulation, think horses not zebras: A clotted sample from a patient with congenital disorder of glycosylation. Int J Lab Hematol 2023 Feb; 45 (1):e6-e9 Epub 2022 Aug 10
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  24. Tefferi A, Singh A, Gangat N, Al-Kali A, Alkhateeb H, Shah M, Patnaik MS, Elliott MA, Hogan WJ, Litzow MR, Wolanskyj-Spinner A, Hook CC, Mangaonkar A, Viswanatha D, Chen D, Pardanani A, Begna KH, Ketterling RP. Adverse karyotype subcategories in acute myeloid leukemia display significant differences in mutation composition and transplant-augmented survival. Haematologica 2023 Jan 1; 108 (1):245-249 Epub 2023 Jan 01
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  25. Kanack AJ, Jones CG, Singh B, Leger RR, Splinter NP, Heikal NM, Pruthi RK, Chen D, George G, Abou-Ismail MY, Wool GD, Gundabolu K, Padmanabhan A. Off-the-shelf cryopreserved platelets for the detection of HIT and VITT antibodies. Blood. 2022 Dec 22; 140 (25):2722-2729
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  26. Mascarenhas J, Kremyanskaya M, Patriarca A, Harrison C, Bose P, Rampal RK, Palandri F, Devos T, Passamonti F, Hobbs G, Talpaz M, Vannucchi A, Kiladjian JJ, Verstovsek S, Hoffman R, Salama ME, Chen D, Taverna P, Chang A, Colak G, Klein S, Gupta V. MPN-375 BET Inhibitor Pelabresib (CPI-0610) Combined With Ruxolitinib in Patients With Myelofibrosis - JAK Inhibitor-Naie or With Suboptimal Response to Ruxolitinib - Preliminary Data From the MANIFEST Study. Clin Lymphoma Myeloma Leuk. 2022 Oct; 22 Suppl 2:S335-S336
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  27. Tefferi A, Gangat N, Shah M, Alkhateeb H, Patnaik MS, Al-Kali A, Elliott MA, Hogan WJ, Litzow MR, Hook CC, Mangaonkar A, Viswanatha D, Chen D, Pardanani A, Ketterling RP, Begna KH. Daunorubicin-60 versus daunorubicin-90 versus idarubicin-12 for induction chemotherapy in acute myeloid leukemia: a retrospective analysis of the Mayo Clinic experience. Haematologica. 2022 Oct 1; 107 (10):2474-2479 Epub 2022 Oct 01
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  28. Salazar E, Long TA, Smock KJ, Wool GD, Rollins-Raval M, Chen D, Harris NS, Chan CW, Olson JD, Pham HP, Ritter J, Unold D, VanSandt AM, Goodwin Iv AJ. Analysis of College of American Pathologists von Willebrand Factor Proficiency Testing Program. Semin Thromb Hemost. 2022 Sep 5 Epub 2022 Sept 05
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  29. Salazar E, Long TA, Smock KJ, Wool GD, Rollins-Raval M, Chen D, Harris NS, Chan CW, Olson JD, Pham HP, Ritter J, Unold D, VanSandt AM, Goodwin Iv AJ. Analysis of College of American Pathologists von Willebrand Factor Proficiency Testing Program. Semin Thromb Hemost. 2022 Sep; 48 (6):690-699 Epub 2022 Oct 12
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  30. Salazar E, Long TA, Smock KJ, Wool GD, Rollins-Raval M, Chen D, Harris NS, Chan CW, Olson JD, Pham HP, Ritter J, Unold D, VanSandt AM, Goodwin Iv AJ. Analysis of College of American Pathologists von Willebrand Factor Proficiency Testing Program. Semin Thromb Hemost. 2022 Sep; 48 (6):690-699 Epub 2022 Sept 02
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  31. Tefferi A, Gangat N, Al-Kali A, Alkhateeb H, Shah M, Patnaik MS, Elliott MA, Hogan WJ, Litzow MR, Hook CC, Mangaonkar A, Viswanatha D, Chen D, Pardanani A, Ketterling RP, DiNardo CD, Kadia TM, Ravandi F, Sasaki K, Begna KH. A dynamic 3-factor survival model for acute myeloid leukemia that accounts for response to induction chemotherapy. Am J Hematol. 2022 Sep; 97 (9):1127-1134 Epub 2022 June 30
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  32. Alkhateeb HB, Mohty R, Greipp P, Bansal R, Hathcock M, Rosenthal A, Murthy H, Kharfan-Dabaja M, Bisneto Villasboas JC, Bennani N, Ansell SM, Patnaik MM, Litzow MR, He R, Chen D, Al-Kali A, Kenderian SS, Lin Y, Shah MV. Therapy-related myeloid neoplasms following chimeric antigen receptor T-cell therapy for Non-Hodgkin Lymphoma. Blood Cancer J 2022 Jul 26; 12 (7):113 Epub 2022 July 26
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  33. Shah MV, Mangaonkar AA, Begna KH, Alkhateeb HB, Greipp P, Nanaa A, Elliott MA, Hogan WJ, Litzow MR, McCullough K, Tefferi A, Gangat N, Patnaik MM, Al-Kali A, He R, Chen D. Therapy-related clonal cytopenia as a precursor to therapy-related myeloid neoplasms. Blood Cancer J. 2022 Jul 8; 12 (7):106 Epub 2022 July 08
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  34. Matsumoto NP, Yuan J, Wang J, Shen Q, Chen X, Kim Y, Zuppan CW, Chang CC, Cui W, Chen D, Shi M, Gisriel SD, Chen M, Xu ML, Pan Z. Mast cell sarcoma: clinicopathologic and molecular analysis of 10 new cases and review of literature. Mod Pathol. 2022 Jul; 35 (7):865-874 Epub 2022 Feb 01
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  35. Sridharan M, D Navitskas S, M Kock E, E Houghton D, Houghton D, Heikal NM, M Heikal N, Chen D, Pruthi R, K Pruthi R. Evaluation of soluble fibrin monomer complex in patients in SARS-CoV-2 COVID-19 infection-associated coagulopathy. Eur J Haematol. 2022 Apr; 108 (4):319-326 Epub 2022 Jan 10
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  36. He R, Chiou J, Chiou A, Chen D, Chen CP, Spethman C, Bessonen KR, Oliveira JL, Nguyen PL, Reichard KK, Hoyer JD, Althoff SD, Roh DJ, Miller MA, Yuan J, Olteanu H, Begna K, Tefferi A, Alkhateeb H, Patnaik MM, Litzow MR, Al-Kali A, Viswanatha DS. Molecular markers demonstrate diagnostic and prognostic value in the evaluation of myelodysplastic syndromes in cytopenia patients. Blood Cancer J. 2022 Jan 25; 12(1):12.
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  37. He R, Chiou J, Chiou A, Chen D, Chen CP, Spethman C, Bessonen KR, Oliveira JL, Nguyen PL, Reichard KK, Hoyer JD, Althoff SD, Roh DJ, Miller MA, Yuan J, Olteanu H, Begna K, Tefferi A, Alkhateeb H, Patnaik MM, Litzow MR, Al-Kali A, Viswanatha DS. Molecular markers demonstrate diagnostic and prognostic value in the evaluation of myelodysplastic syndromes in cytopenia patients. Blood Cancer J 2022 Jan 25; 12 (1):12
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  38. Volod O, Rollins-Raval M, Goodwin AJ, Higgins RA, Long T, Chandler WL, Harris NS, Pham HP, Isom JA, Moser K, Olson JD, Smock KJ, VanSandt A, Wool G, Chen D. Interlaboratory Performance in Measurement of Dabigatran and Rivaroxaban. Arch Pathol Lab Med. 2022 Jan 2; 146 (2):145-153
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  39. Jawad M, Afkhami M, Ding Y, Zhang X, Li P, Young K, Xu ML, Cui W, Zhao Y, Halene S, Al-Kali A, Viswanatha D, Chen D, He R, Zheng G. DNMT3A R882 Mutations Confer Unique Clinicopathologic Features in MDS Including a High Risk of AML Transformation. Front Oncol. 2022; 12:849376 Epub 2022 Feb 28
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  40. Goswami J, MacArthur TA, Sridharan M, Tange J, Kirmse AJ, Lundell KA, Chen D, Auton MT, Chon TY, Hurt RT, Salonen BR, Ganesh R, Erben YM, Marquez CP, Dong JF, Kozar RA, Heller SF, Loomis EA, Johnstone AL, Bailey KR, Spears GM, Park MS. Biomarkers of thromboinflammation correlate to COVID-19 infection and admission status in emergency department patients. Thromb Update. 2021 Dec; 5:100090 Epub 2021 Nov 19
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  41. Zheng G, He R, Reichard KK, Peterson JF, Olteanu H, Oliveira JL, Rangan A, Chen D, Shi M. Genetic and Clinical Studies of Patients With Increased Multinucleated Megakaryocytes in Bone Marrow as an Isolated Finding: A Diagnostic Pitfall for Myelodysplastic Syndrome. Am J Surg Pathol. 2021 Nov 1; 45 (11):1534-1540
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  42. Martin ES, Ferrer A, Mangaonkar AA, Khan SP, Kohorst MA, Joshi AY, Hogan WJ, Olteanu H, Moyer AM, Al-Kali A, Tefferi A, Chen D, Wudhikarn K, Go R, Viswanatha D, He R, Ketterling R, Nguyen PL, Oliveira JL, Gangat N, Lasho T, Patnaik MM. Spectrum of hematological malignancies, clonal evolution and outcomes in 144 Mayo Clinic patients with germline predisposition syndromes. Am J Hematol. 2021 Nov 1; 96 (11):1450-1460 Epub 2021 Aug 27
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  43. Seheult JN, Dalenberg D, Sridharan MR, Stuart M, Moericke K, Cardel L, Heikal N, Chen D, Pruthi RK. Revisiting the effects of spectral interfering substances in optical end-point coagulation assays. Int J Lab Hematol. 2021 Oct; 43(5):1181-1190. Epub 2021 Jan 17.
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  44. Lansdon LA, Chen D, Rush ET, Engleman K, Zhang L, Saunders CJ, Oroszi G. A novel likely pathogenic variant in a patient with Hermansky-Pudlak syndrome. Cold Spring Harb Mol Case Stud. 2021 Oct; 7 (5) Epub 2021 Oct 19
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  45. Venable ER, Chen D, Chen CP, Bessonen KR, Nguyen PL, Oliveira JL, Reichard KK, Hoyer JD, Althoff SD, Roh DJ, Miller MA, Begna K, Patnaik MM, Litzow MR, Al-Kali A, Viswanatha DS, He R. Pathologic Spectrum and Molecular Landscape of Myeloid Disorders Harboring SF3B1 Mutations. Am J Clin Pathol. 2021 Sep 8; 156 (4):679-690
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  46. Zhang M, Jin L, Duan YL, Yang J, Huang S, Jin M, Zhu GH, Gao C, Liu Y, Zhang N, Zhou CJ, Gao ZF, Zheng QL, Chen D, Zhang YH. Diagnosis and treatment of pediatric anaplastic lymphoma kinase-positive large B-cell lymphoma: A case report. World J Clin Cases. 2021 Jun 16; 9 (17):4268-4278
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  47. Fang H, Yabe M, Zhang X, Kim Y, Wu X, Wei P, Chi S, Zheng L, Garcia-Manero G, Shao L, Yuan J, Shen Y, Zheng G, Tang G, Wang W, Loghavi S, Shen Q, Yuan Y, He R, Chen D, Medeiros LJ, Hu S. Myelodysplastic syndrome with t(6;9)(p22;q34.1)/DEK-NUP214 better classified as acute myeloid leukemia? A multicenter study of 107 cases. Mod Pathol. 2021 Jun; 34 (6):1143-1152 Epub 2021 Feb 08
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  48. Han SY, Mrozek K, Voutsinas J, Wu Q, Morgan EA, Vestergaard H, Ohgami R, Kluin PM, Kristensen TK, Pullarkat S, Moller MB, Schiefer AI, Baughn LB, Kim Y, Czuchlewski D, Hilberink JR, Horny HP, George TI, Dolan M, Ku NK, Arana Yi C, Pullarkat V, Kohlschmidt J, Salhotra A, Soma L, Bloomfield CD, Chen D, Sperr WR, Marcucci G, Cho C, Akin C, Gotlib J, Broesby-Olsen S, Larson M, Linden MA, Deeg HJ, Hoermann G, Perales MA, Hornick JL, Litzow MR, Nakamura R, Weisdorf D, Borthakur G, Huls G, Valent P, Ustun C, Yeung CCS. Secondary cytogenetic abnormalities in core-binding factor AML harboring inv(16) vs t(8;21). Blood Adv. 2021 May 25; 5 (10):2481-2489
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  49. Nadiminti K, Sidiqi MH, Meleveedu K, Alkhateeb HB, Hogan WJ, Litzow M, Patnaik M, Kumar S, Gertz M, Chen D, Shah MV. Characteristics and outcomes of therapy-related myeloid neoplasms following autologous stem cell transplantation for multiple myeloma. Blood Cancer J 2021 Mar 19; 11 (3):63
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  50. Begna KH, Ali W, Naseema Gangat Gangat, Elliott MA, Al-Kali A, Litzow MR, Christopher Hook C, Wolanskyj-Spinner AP, Hogan WJ, Patnaik MM, Pardanani A, Zblewski DL, Chen D, He R, Viswanatha D, Hanson CA, Ketterling RP, Tefferi A. Mayo Clinic experience with 1123 adults with acute myeloid leukemia. Blood Cancer J. 2021 Mar 2; 11 (3):46 Epub 2021 Mar 02
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  51. Meleveedu KS, Chen D, Nadiminti K, Sidiqi H, Khan S, Alkhateeb H, Shah MV, Patnaik M, Hogan WJ, Begna K, Litzow M. PD-1/PD-L1 expression in extramedullary lesions of acute myeloid leukemia. Leuk Lymphoma 2021 Mar; 62 (3):764-767 Epub 2019 Oct 12
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  52. Samuelson Bannow B, Warad DM, Jones CG, Pechauer SM, Curtis BR, Bougie DW, Sharma R, Grill DE, Redman MW, Khalighi PR, Leger RR, Pruthi RK, Chen D, Sabath DE, Aster RH, Garcia DA, Padmanabhan A. A prospective, blinded study of a PF4-dependent assay for HIT diagnosis. Blood. 2021 Feb 25; 137 (8):1082-1089
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  53. Ustun C, Morgan EA, Ritz EM, Vestergaard H, Pullarkat S, Kluin PM, Ohgami R, Baughn LB, Kim Y, Ku NK, Czuchlewski D, Boe Moller M, Schiefer AI, Mrozek K, Horny HP, George TI, Kielsgaard Kristensen T, Beck T, Nathan S, Arana Yi C, Yeung C, Pullarkat V, Gotlib J, Akin C, Kohlschmidt J, Salhotra A, Soma L, Chen D, Han SY, Cho C, Sperr W, Broesby-Olsen S, Linden MA, Dolan M, Hoermann G, Hornick JL, Bloomfield C, Nakamura R, Joachim Deeg H, Litzow MR, Borthakur G, Weisdorf D, Huls G, Perales MA, Valent P, Marcucci G. Core-binding factor acute myeloid leukemia with inv(16): Older age and high white blood cell count are risk factors for treatment failure. Int J Lab Hematol 2021 Feb; 43 (1):e19-e25 Epub 2020 Sept 14
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  54. Mattson MK, Groves C, Smith MM, Christensen JM, Chen D, Stubbs JR, Karon BS, Nuttall GA. Platelet transfusion: The effects of a fluid warmer on platelet function. Transfusion. 2021 Jan; 61 (1):52-56 Epub 2020 Oct 19
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  55. Seheult JN, Cardel L, Tange JI, Ashrani A, Nichols WL, Heikal N, Chen D. An In Silico Exploration of the Factors That Affect the Precision of the Bethesda Assay. Am J Clin Pathol. 2020 Oct 13; 154(5):671-682.
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  56. Heybeli C, Sridharan M, Alkhateeb HB, Villasboas Bisneto JC, Buadi FK, Chen D, Dingli D, Dispenzieri A, Gertz MA, Go RS, Hashmi SK, Hayman SR, Hogan WJ, Inwards DJ, Kenderian SS, Kumar SK, Litzow MR, Porrata LF, Lacy MQ, Micallef IN, Patnaik MM, Shah MV, Leung N. Characteristics of late transplant-associated thrombotic microangiopathy in patients who underwent allogeneic hematopoietic stem cell transplantation. Am J Hematol. 2020 Oct; 95 (10):1170-1179 Epub 2020 Aug 08
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  57. DiFilippo EC, Coltro G, Carr RM, Mangaonkar AA, Binder M, Khan SP, Rodriguez V, Gangat N, Wolanskyj A, Pruthi RK, Chen D, He R, Viswanatha DS, Lasho T, Finke C, Tefferi A, Pardanani A, Patnaik MM. Spectrum of abnormalities and clonal transformation in germline RUNX1 familial platelet disorder and a genomic comparative analysis with somatic RUNX1 mutations in MDS/MPN overlap neoplasms. Leukemia 2020 Sep; 34 (9):2519-2524 Epub 2020 Feb 14
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  58. Saliba AN, Ferrer A, Gangat N, Pruthi RK, Tefferi A, Higgins A, Bezerra ED, Buglioni A, Salama ME, Klee EW, Pinto E Vairo F, Mangaonkar A, Majerus J, Chen D, Patnaik MM. Aetiology and outcomes of secondary myelofibrosis occurring in the context of inherited platelet disorders: A single institutional study of four patients. Br J Haematol 2020 Sep; 190 (5):e316-e320 Epub 2020 June 22
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  59. Moser KA, Pearson LN, Pelt CE, Olson JD, Goodwin AJ, Isom JA, Harris NS, Pham HP, Smock KJ, Unold D, VanSandt AM, Volod O, Chen D. Letter to the Editor on "The 2018 Definition of Periprosthetic Hip and Knee Infection: An Evidence-Based and Validated Criteria". J Arthroplasty 2020 Sep; 35 (9):2682-2683 Epub 2020 May 11
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  60. He R, Devine DJ, Tu ZJ, Mai M, Chen D, Nguyen PL, Oliveira JL, Hoyer JD, Reichard KK, Ollila PL, Al-Kali A, Tefferi A, Begna KH, Patnaik MM, Alkhateeb H, Viswanatha DS. Hybridization capture-based next generation sequencing reliably detects FLT3 mutations and classifies FLT3-internal tandem duplication allelic ratio in acute myeloid leukemia: a comparative study to standard fragment analysis. Mod Pathol. 2020 Mar; 33 (3):334-343 Epub 2019 Aug 30
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  61. He R, Devine DJ, Tu ZJ, Mai M, Chen D, Nguyen PL, Oliveira JL, Hoyer JD, Reichard KK, Ollila PL, Al-Kali A, Tefferi A, Begna KH, Patnaik MM, Alkhateeb H, Viswanatha DS. Correction to: Hybridization capture-based next-generation sequencing reliably detects FLT3 mutations and classifies FLT3-internal tandem duplication allelic ratio in acute myeloid leukemia: a comparative study to standard fragment analysis. Mod Pathol. 2020 Mar; 33(3):514.
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  62. Liu S, Deng B, Yin Z, Pan J, Lin Y, Ling Z, Wu T, Chen D, Chang AH, Gao Z, Song Y, Zhao Y, Tong C. Corticosteroids do not influence the efficacy and kinetics of CAR-T cells for B-cell acute lymphoblastic leukemia. Blood Cancer J 2020 Feb 6; 10 (2):15 Epub 2020 Feb 06
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  63. Blackburn PR, Huang L, Dalovisio A, Pitel BA, Chen D, Oliveira JL, Wood AJ, Smadbeck JB, Johnson SH, Vasmatzis G, Haferlach C, Greipp PT, Hoppman NL, Ketterling RP, Baughn LB, Peterson JF. Secondary acquisition of BCR-ABL1 fusion in de novo GATA2-MECOM positive acute myeloid leukemia with subsequent emergence of a rare KMT2A-ASXL2 fusion. Cancer Genet 2020 Feb; 241:67-71 Epub 2019 Dec 26
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  64. Shi M, Rech KL, Otteson GE, Horna P, Olteanu H, Pardanani A, Chen D, Jevremovic D. Prevalence and spectrum of T-cell lymphoproliferative disorders in patients with Hypereosinophilia: A reference laboratory experience. Ann Diagn Pathol. 2020 Feb; 44:151412 Epub 2019 Oct 18
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  65. Ravindran A, He R, Ketterling RP, Jawad MD, Chen D, Oliveira JL, Nguyen PL, Viswanatha DS, Reichard KK, Hoyer JD, Go RS, Shi M. The significance of genetic mutations and their prognostic impact on patients with incidental finding of isolated del(20q) in bone marrow without morphologic evidence of a myeloid neoplasm. Blood Cancer J. 2020 Jan 23; 10 (1):7
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  66. Tischer A, Brehm MA, Machha VR, Moon-Tasson L, Benson LM, Nelton KJ, Leger RR, Obser T, Martinez-Vargas M, Whitten ST, Chen D, Pruthi RK, Bergen HR 3rd, Cruz MA, Schneppenheim R, Auton M. Evidence for the Misfolding of the A1 Domain within Multimeric von Willebrand Factor in Type 2 von Willebrand Disease. J Mol Biol. 2020 Jan 17; 432 (2):305-323 Epub 2019 Oct 17
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  67. Baidoun F, Chen D, Patnaik M, Gangat N, Begna K, Elliott M, Hogan W, Litzow M, Al-Kali A. Clinical outcome of patients diagnosed with myelodysplastic syndrome-unclassifiable (MDS-U): single center experience. Leuk Lymphoma. 2019 Oct; 60 (10):2483-2487 Epub 2019 Mar 07
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  68. Bansal A, Uriel N, Colombo PC, Narisetty K, Long JW, Bhimaraj A, Cleveland JC Jr, Goldstein DJ, Stulak JM, Najjar SS, Lanfear DE, Adler ED, Dembitsky WP, Somo SI, Crandall DL, Chen D, Connors JM, Mehra MR. Effects of a fully magnetically levitated centrifugal-flow or axial-flow left ventricular assist device on von Willebrand factor: A prospective multicenter clinical trial. J Heart Lung Transplant. 2019 Aug; 38 (8):806-816 Epub 2019 May 17
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  69. Nicoli ER, Weston MR, Hackbarth M, Becerril A, Larson A, Zein WM, Baker PR 2nd, Burke JD, Dorward H, Davids M, Huang Y, Adams DR, Zerfas PM, Chen D, Markello TC, Toro C, Wood T, Elliott G, Vu M, Undiagnosed Diseases Network, Zheng W, Garrett LJ, Tifft CJ, Gahl WA, Day-Salvatore DL, Mindell JA, Malicdan MCV. Lysosomal Storage and Albinism Due to Effects of a De Novo CLCN7 Variant on Lysosomal Acidification. Am J Hum Genet. 2019 Jun 06; 104(6):1127-1138. Epub 2019 May 30.
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  70. Peterson JF, Baughn LB, Ketterling RP, Pitel BA, Smoley SA, Vasmatzis G, Smadbeck JB, Greipp PT, Mangaonkar AA, Thompson CA, Parikh SA, Chen D, Viswanatha DS. Characterization of a cryptic IGH/CCND1 rearrangement in a case of mantle cell lymphoma with negative CCND1 FISH studies. Blood Adv. 2019 Apr 23; 3 (8):1298-1302
    View PubMed
  71. Chandler WL, Brown AF, Chen D, Moser K, Olson JD, Pham HP, Smock KJ, Volod O, Higgins RA. External Quality Assurance of Platelet Function Assays: Results of the College of American Pathologists Proficiency Testing Program. Arch Pathol Lab Med. 2019 Apr; 143 (4):472-482 Epub 2018 Dec 21
    View PubMed
  72. Fylling KA, Tange JI, Chen D, Pruthi RK. Heat inactivation of extended half-life factor VIII concentrates. Haemophilia 2019 Mar; 25 (2):e130-e131 Epub 2019 Feb 12
    View PubMed
  73. Power B, Ferreira CR, Chen D, Zein WM, O'Brien KJ, Introne WJ, Stephen J, Gahl WA, Huizing M, Malicdan MCV, Adams DR, Gochuico BR. Hermansky-Pudlak syndrome and oculocutaneous albinism in Chinese children with pigmentation defects and easy bruising. Orphanet J Rare Dis. 2019 Feb 21; 14 (1):52
    View PubMed
  74. Sridharan M, Coon LM, Chen D, Pruthi RK. Factor V Deficiency with a Thrombotic Clinical Phenotype. Semin Thromb Hemost 2019 Feb; 45 (1):108-112 Epub 2019 Jan 10
    View PubMed
  75. Han CG, O'Brien KJ, Coon LM, Majerus JA, Huryn LA, Haroutunian SG, Moka N, Introne WJ, Macnamara E, Gahl WA, Malicdan MCV, Chen D, Krishnan K, Gochuico BR. Severe bleeding with subclinical oculocutaneous albinism in a patient with a novel HPS6 missense variant. Am J Med Genet A. 2018 Dec; 176 (12):2819-2823 Epub 2018 Oct 04
    View PubMed
  76. Begna KH, Ali W, Gangat N, Elliott MA, Al-Kali A, Litzow MR, Hook CC, Wolanskyj AP, Hogan WJ, Patnaik MM, Pardanani A, Zblewski DL, Chen D, He R, Viswanatha D, Hanson CA, Ketterling RP, Tefferi A. A novel predictive model of outcome in acute myeloid leukemia without favorable karyotype based on treatment strategy, karyotype and FLT3-ITD mutational status. Am J Hematol 2018 Dec; 93 (12):E401-E404 Epub 2018 Oct 17
    View PubMed
  77. Neff JL, Rangan A, Jevremovic D, Nguyen PL, Chiu A, Go RS, Chen D, Morice WG, Shi M, Shi M. Mixed-phenotype large granular lymphocytic leukemia: a rare subtype in the large granular lymphocytic leukemia spectrum. Hum Pathol. 2018 Nov; 81:96-104 Epub 2018 June 24
    View PubMed
  78. Thompson G, Sekiguchi H, Chen D, Ryu JH. A 40-Year-Old Man With Albinism and Progressive Dyspnea. Chest. 2018 Nov; 154 (5):e143-e146
    View PubMed
  79. Sridharan M, Fylling KA, Ashrani AA, Chen D, Marshall AL, Hook CC, Cardel LK, Nichols WL, Pruthi RK. Clinical and laboratory diagnosis of autoimmune factor V inhibitors: A single institutional experience. Thromb Res. 2018 Nov; 171:14-21 Epub 2018 Sept 05
    View PubMed
  80. Wang L, Lanka L, Chen D, Pruthi RK. Severe postoperative hemorrhage in a patient on dietary and herbal supplements. J Perioper Pract. 2018 Oct; 28 (10):263-266 Epub 2018 June 11
    View PubMed
  81. Fang H, Ketterling RP, Hanson CA, Pardanani A, Kurtin PJ, Chen D, Greipp PT, Howard MT, King RL, Van Dyke DL, Reichard KK. A Test Utilization Approach to the Diagnostic Workup of Isolated Eosinophilia in Otherwise Morphologically Unremarkable Bone Marrow: A Single Institutional Experience. Am J Clin Pathol. 2018 Oct 1; 150 (5):421-431
    View PubMed
  82. Pruthi Rajiv, K., Chen Dong. Platelet Transmission Electron Microscopy The Clotting Times (ECAT Foundation). Sep 2018(6):x-xx. 2018.
  83. Chen D, Uhl CB, Bryant SC, Krumwiede M, Barness RL, Olson MC, Gossman SC, Erdogan Damgard S, Gamb SI, Cummins LA, Charlesworth JE, Wood-Wentz CM, Salisbury JL, Plumhoff EA, Van Cott EM, He R, Warad DM, Pruthi RK, Heit JA, Nichols WL, White JG. Diagnostic laboratory standardization and validation of platelet transmission electron microscopy. Platelets. 2018 Sep; 29(6):574-582. Epub 2018 Jun 04.
    View PubMed
  84. Ustun C, Morgan E, Moodie EEM, Pullarkat S, Yeung C, Broesby-Olsen S, Ohgami R, Kim Y, Sperr W, Vestergaard H, Chen D, Kluin PM, Dolan M, Mrozek K, Czuchlewski D, Horny HP, George TI, Kristensen TK, Ku NK, Yi CA, Moller MB, Marcucci G, Baughn L, Schiefer AI, Hilberink JR, Pullarkat V, Shanley R, Kohlschmidt J, Coulombe J, Salhotra A, Soma L, Cho C, Linden MA, Akin C, Gotlib J, Hoermann G, Hornick J, Nakamura R, Deeg J, Bloomfield CD, Weisdorf D, Litzow MR, Valent P, Huls G, Perales MA, Borthakur G. Core-binding factor acute myeloid leukemia with t(8;21): Risk factors and a novel scoring system (I-CBFit). Cancer Med. 2018 Sep; 7 (9):4447-4455 Epub 2018 Aug 16
    View PubMed
  85. Blackshear JL, Pollak PM, Chen D. Impact of mitral valve clip procedure on indices of acquired von Willebrand syndrome Research and Practice in Thrombosis and Haemostasis. 2018; 2:PB278.
  86. He R, Ding W, Viswanatha DS, Chen D, Shi M, Van Dyke D, Tian S, Dao LN, Parikh SA, Shanafelt TD, Call TG, Ansell SM, Leis JF, Mai M, Hanson CA, Rech KL. PD-1 Expression in Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) and Large B-cell Richter Transformation (DLBCL-RT): A Characteristic Feature of DLBCL-RT and Potential Surrogate Marker for Clonal Relatedness. Am J Surg Pathol. 2018 Jul; 42 (7):843-854
    View PubMed
  87. Perez Botero J, Ho TP, Hogan WJ, Kenderian S, Gangat N, Tefferi A, Abraham RS, Nguyen P, Oliveira JL, He R, Chen D, Viswanatha D, Rodriguez V, Khan SP, Patnaik MM. Clinical spectrum and clonal evolution in germline syndromes with predisposition to myeloid neoplasms. Br J Haematol. 2018 Jul; 182(1):141-145. Epub 2017 May 09.
    View PubMed
  88. Rangan A, Oliveira JL, Jevremovic D, Morice WG, Chen D, Shi m. Pure red cell aplasia due to T-cell large granular lymphocytic leukemia after hematopoietic stem cell transplantation AJSP: Reviews & Reports.. 2018; 23(3):p e1-e4.
  89. Perez Botero J, Coon LM, Majerus JA, Chen D, Pruthi RK. Factor IX Gene (F9) Genotyping Trends and Spectrum of Mutations Identified: A Reference Laboratory Experience. Semin Thromb Hemost. 2018 Apr; 44 (3):287-292 Epub 2017 Sept 13
    View PubMed
  90. Shi M, He R, Feldman AL, Viswanatha DS, Jevremovic D, Chen D, Morice WG. STAT3 mutation and its clinical and histopathologic correlation in T-cell large granular lymphocytic leukemia. Hum Pathol. 2018 Mar; 73:74-81 Epub 2017 Dec 27
    View PubMed
  91. Shi M, Ternus JA, Chen D. Greatly increased giant platelets mimicking blasts in flow cytometric analysis from a patient with primary myelofibrosis J Hematopathol. 2018; 11:21-22.
  92. Botero JP, Chen D, Majerus JA, Coon LM, He R, Warad DM, Pruthi RK, Nichols WL. Hermansky-Pudlak syndrome subtype 5 (HPS-5) novel mutation in a 65 year-old with oculocutaneous hypopigmentation and mild bleeding diathesis: The importance of recognizing a subtle phenotype. Platelets. 2018 Jan; 29(1):91-94. Epub 2017 Nov 01.
    View PubMed
  93. Austin CO, Chen D, Thomas CS, Safford RE, Shapiro BP, Bryan JA, Ray JC, Blackshear JL. Von Willebrand factor multimer quantitation for assessment of cardiac lesion severity and bleeding risk. Res Pract Thromb Haemost. 2018 Jan; 2 (1):155-161 Epub 2017 Dec 21
    View PubMed
  94. Conboy E, Partain PI, Warad D, Kluge ML, Arndt C, Chen D, Rodriguez V. A Severe Case of Congenital Thrombotic Thrombocytopenia Purpura Resulting From Compound Heterozygosity Involving a Novel ADAMTS13 Pathogenic Variant. J Pediatr Hematol Oncol. 2018 Jan; 40 (1):60-62
    View PubMed
  95. Austin Chistopher, Chen Dong, Thomas Colleen, Safford Robert, Shapiro Brian, Bryan Justin, Ray Jordan, Blackshear Joseph. Von Willebrand factor multimer quantitation for assessment of cardiac lesion severity and bleeding risk Research and Practice in Thrombosis and Haemostasis.12/21/2017;2017:(00):1-7.
  96. Haddox CL, Mangaonkar AA, Chen D, Shi M, He R, Oliveira JL, Litzow MR, Al-Kali A, Hogan WJ, Elliott MA. Blinatumomab-induced lineage switch of B-ALL with t(4:11)(q21;q23) KMT2A/AFF1 into an aggressive AML: pre- and post-switch phenotypic, cytogenetic and molecular analysis. Blood Cancer J 2017 Sep 15; 7 (9):e607 Epub 2017 Sept 15
    View PubMed
  97. Perez Botero J, Chen D, Cousin MA, Majerus JA, Coon LM, Kruisselbrink TM, Klee EW, Lazaridis KN, Pruthi RK, Patnaik MM. Clinical characteristics and platelet phenotype in a family with RUNX1 mutated thrombocytopenia. Leuk Lymphoma 2017 Aug; 58 (8):1963-1967 Epub 2016 Dec 08
    View PubMed
  98. Perez Botero J, Chen D, Cousin MA, Majerus JA, Coon LM, Kruisselbrink TM, Klee EW, Lazaridis KN, Pruthi RK, Patnaik MM. Clinical characteristics and platelet phenotype in a family with RUNX1 mutated thrombocytopenia. Leuk Lymphoma. 2017 Aug; 58(8):1963-1967. Epub 2016 Dec 08.
    View PubMed
  99. Perez Botero J, Warad DM, He R, Uhl CB, Tian S, Otteson GE, Barness RL, Olson MC, Gossman SC, Charlesworth JE, Nichols WL, Pruthi RK, Chen D. Comprehensive Platelet Phenotypic Laboratory Testing and Bleeding History Scoring for Diagnosis of Suspected Hereditary Platelet Disorders: A Single-Institution Experience. Am J Clin Pathol. 2017 Jul 01; 148(1):23-32.
    View PubMed
  100. Perez Botero J, Pruthi RK, Majerus JA, Coon LM, Uhl CB, Chen D, Patnaik MM. Practice patterns in the diagnosis of inherited platelet disorders within a single institution. Blood Coagul Fibrinolysis. 2017 Jun; 28 (4):303-308
    View PubMed
  101. Perez Botero J, Majerus JA, Strege AK, Johnson RD, Chen D, Pruthi RK. Diagnostic Testing Approaches for Activated Protein C Resistance and Factor V Leiden: A Comparison of Institutional and National Provider Practices. Am J Clin Pathol. 2017 Jun 1; 147 (6):604-610
    View PubMed
  102. Shi M, Chen D. Erythrophagocytosis by neutrophils and megakaryocytic emperipolesis are distinctive morphologic features in del(20q)-associated myelodysplastic syndrome Human Pathology: Case Reports .2017;S2214-3300(16)30138-9.
  103. Goodwin AJ, Higgins RA, Moser KA, Smock KJ, Chandler WL, Kottke-Marchant K, Hartman SK, Volod O, Brown AF, Johari VP, Burr S, Polyakov N, Chen D. Issues Surrounding Age-Adjusted d-Dimer Cutoffs That Practicing Physicians Need to Know When Evaluating Patients With Suspected Pulmonary Embolism. Ann Intern Med. 2017 Mar 7; 166 (5):361-363 Epub 2016 Dec 27
    View PubMed
  104. Ferreira CR, Chen D, Abraham SM, Adams DR, Simon KL, Malicdan MC, Markello TC, Gunay-Aygun M, Gahl WA. Combined alpha-delta platelet storage pool deficiency is associated with mutations in GFI1B. Mol Genet Metab. 2017 Mar; 120 (3):288-294 Epub 2016 Dec 18
    View PubMed
  105. Stephen J, Yokoyama T, Tolman NJ, O'Brien KJ, Nicoli ER, Brooks BP, Huryn L, Titus SA, Adams DR, Chen D, Gahl WA, Gochuico BR, Malicdan MC. Cellular and molecular defects in a patient with Hermansky-Pudlak syndrome type 5. PLoS One. 2017; 12 (3):e0173682 Epub 2017 Mar 15
    View PubMed
  106. Neff Jadee, Chen Dong. Pediatric Philadelphia-Positive B Lymphoblastic Leukemia with CD56 Expression and L2 Morphology: Case Report and Review of the Literature Human Pathology Case Reports.6/2017;8:9-12.
  107. Neff JL, Chen D. Hepatosplenic T-cell lymphoma with blastoid morphology in a patient with Crohn disease. Blood. 2016 Nov 3; 128 (18):2275
    View PubMed
  108. Perez Botero J, Chen D, He R, Viswanatha DS, Majerus JA, Coon LM, Nguyen PL, Reichard KK, Oliveira JL, Tefferi A, Gangat N, Pruthi RK, Patnaik MM. Clinical and laboratory characteristics in congenital ANKRD26 mutation-associated thrombocytopenia: A detailed phenotypic study of a family. Platelets. 2016 Nov; 27 (7):712-715 Epub 2016 Apr 28
    View PubMed
  109. Van Cott EM, Smock KJ, Chen D, Hsu P, Zantek ND, Meijer P. Testing for dabigatran and rivaroxaban by clinical laboratories. Am J Hematol. 2016 Nov; 91: (11)E464-E467.
    View PubMed
  110. Go RS, Winters JL, Leung N, Murray DL, Willrich MA, Abraham RS, Amer H, Hogan WJ, Marshall AL, Sethi S, Tran CL, Chen D, Pruthi RK, Ashrani AA, Fervenza FC, Cramer CH 2nd, Rodriguez V, Wolanskyj AP, Thomé SD, Hook CC, Mayo Clinic Complement Alternative Pathway-Thrombotic Microangiopathy Disease-Oriented Group. Thrombotic Microangiopathy Care Pathway: A Consensus Statement for the Mayo Clinic Complement Alternative Pathway-Thrombotic Microangiopathy (CAP-TMA) Disease-Oriented Group. Mayo Clin Proc. 2016 Sep; 91(9):1189-211. Epub 2016 Aug 03.
    View PubMed
  111. Pardanani A, Lasho T, Elala Y, Wassie E, Finke C, Reichard KK, Chen D, Hanson CA, Ketterling RP, Tefferi A. Next-generation sequencing in systemic mastocytosis: Derivation of a mutation-augmented clinical prognostic model for survival. Am J Hematol. 2016 Sep; 91 (9):888-93 Epub 2016 June 20
    View PubMed
  112. Perez Botero J, Im R, Chen D, Patnaik MM. Grey platelet syndrome misdiagnosed as ITP. Br J Haematol. 2016 Jun; 173(5):662. Epub 2016 May 12.
    View PubMed
  113. He R, Greipp PT, Rangan A, Mai M, Chen D, Reichard KK, Nelsen LL, Pardanani A, Hanson CA, Viswanatha DS. BCR-JAK2 fusion in a myeloproliferative neoplasm with associated eosinophilia. Cancer Genet. 2016 May; 209: (5)223-8.
    View PubMed
  114. Blackshear JL, McRee CW, Safford RE, Pollak PM, Stark ME, Thomas CS, Rivera CE, Wysokinska EM, Chen D. von Willebrand Factor Abnormalities and Heyde Syndrome in Dysfunctional Heart Valve Prostheses. JAMA Cardiol. 2016 May 1; 1 (2):198-204
    View PubMed
  115. Piovezani Ramos G, Villasboas Bisneto JC, Chen D, Pardanani A. Initial presentation of CNS-restricted acute lymphoblastic B cell leukaemia as peripheral polyneuropathy. BMJ Case Rep. 2016 Apr 19; 2016:10.1136/bcr-2016-214645
    View PubMed
  116. Pardanani A, Reichard KK, Zblewski D, Abdelrahman RA, Wassie EA, Morice WG, Morice Ii WG, Brooks C, Grogg KL, Hanson CA, Tefferi A, Chen D. CD123 immunostaining patterns in systemic mastocytosis: differential expression in disease subgroups and potential prognostic value. Leukemia. 2016 Apr; 30 (4):914-8 Epub 2015 Dec 18
    View PubMed
  117. Blackshear JL, Kusumoto H, Safford RE, Wysokinska E, Thomas CS, Waldo OA, Stark ME, Shapiro BP, Ung S, Moussa I, Agnew RC, Landolfo K, Chen D. Usefulness of Von Willebrand Factor Activity Indexes to Predict Therapeutic Response in Hypertrophic Cardiomyopathy. Am J Cardiol. 2016 Feb 1; 117 (3):436-42 Epub 2015 Nov 19
    View PubMed
  118. Butterfield JH, Chen D. Response of patients with indolent systemic mastocytosis to tamoxifen citrate. Leuk Res. 2016 Jan; 40:10-6.
    View PubMed
  119. Hillarp A, Friedman KD, Adcock-Funk D, Tiefenbacher S, Nichols WL, Chen D, Stadler M, Schwartz BA. Comparison of several von Willebrand factor (VWF) activity assays for monitoring patients undergoing treatment with VWF/FVIII concentrates: improved performance with a new modified automated method. Haemophilia. 2015 Nov; 21: (6)837-45.
    View PubMed
  120. Reichard KK, Chen D, Pardanani A, McClure RF, Howard MT, Kurtin PJ, Wood AJ, Ketterling RP, King RL, He R, Morice WG, Hanson CA. Morphologically occult systemic mastocytosis in bone marrow: clinicopathologic features and an algorithmic approach to diagnosis. Am J Clin Pathol. 2015 Sep; 144(3):493-502.
    View PubMed
  121. Pardanani A, Lasho T, Chen D, Kimlinger TK, Finke C, Zblewski D, Patnaik MM, Reichard KK, Rowinsky E, Hanson CA, Brooks C, Tefferi A. Aberrant expression of CD123 (interleukin-3 receptor-alpha) on neoplastic mast cells. Leukemia 2015 Jul; 29 (7):1605-8 Epub 2015 Feb 02
    View PubMed
  122. Perez Botero J, Oliveira JL, Chen D, Chen D, Reichard KK, Viswanatha DS, Nguyen PL, Pruthi RK, Majerus J, Gada P, Gangat N, Tefferi A, Patnaik MM. ASXL1 mutated chronic myelomonocytic leukemia in a patient with familial thrombocytopenia secondary to germline mutation in ANKRD26. Blood Cancer J 2015 May 22; 5:e315
    View PubMed
  123. Markello T, Chen D, Kwan JY, Horkayne-Szakaly I, Morrison A, Simakova O, Maric I, Lozier J, Cullinane AR, Kilo T, Meister L, Pakzad K, Bone W, Chainani S, Lee E, Links A, Boerkoel C, Fischer R, Toro C, White JG, Gahl WA, Gunay-Aygun M. York platelet syndrome is a CRAC channelopathy due to gain-of-function mutations in STIM1. Mol Genet Metab. 2015 Mar; 114 (3):474-82 Epub 2014 Dec 24
    View PubMed
  124. Blackshear JL, Stark ME, Agnew RC, Moussa ID, Safford RE, Shapiro BP, Waldo OA, Chen D. Remission of recurrent gastrointestinal bleeding after septal reduction therapy in patients with hypertrophic obstructive cardiomyopathy-associated acquired von Willebrand syndrome. J Thromb Haemost. 2015 Feb; 13 (2):191-6 Epub 2014 Dec 12
    View PubMed
  125. Lasho TL, Finke CM, Zblewski D, Patnaik M, Ketterling RP, Chen D, Hanson CA, Tefferi A, Pardanani A. Novel recurrent mutations in ethanolamine kinase 1 (ETNK1) gene in systemic mastocytosis with eosinophilia and chronic myelomonocytic leukemia. Blood Cancer J. 2015 Jan 23; 5:e275
    View PubMed
  126. He R, Hanson CA, Chen D, Oliveira JL, Pardanani A, Reichard KK, Viswanatha DS. Not all CALR mutations are created equal. Leuk Lymphoma 2015; 56 (8):2482-3 Epub 2015 Aug 17
    View PubMed
  127. Karon BS, Tolan NV, Koch CD, Wockenfus AM, Miller RS, Lingineni RK, Pruthi RK, Chen D, Jaffe AS. Precision and reliability of 5 platelet function tests in healthy volunteers and donors on daily antiplatelet agent therapy. Clin Chem. 2014 Dec; 60 (12):1524-31 Epub 2014 Oct 03
    View PubMed
  128. Blackshear JL, Wysokinska EM, Safford RE, Thomas CS, Shapiro BP, Ung S, Stark ME, Parikh P, Johns GS, Chen D. Shear stress-associated acquired von Willebrand syndrome in patients with mitral regurgitation. J Thromb Haemost. 2014 Dec; 12 (12):1966-74 Epub 2014 Oct 17
    View PubMed
  129. Gatt A, Chen D, Pruthi RK, Kamath PS, Leise MD, Ashrani AA, Nichols WL, He R. From vitamin K antagonists to liver international normalized ratio: a historical journey and critical perspective. Semin Thromb Hemost. 2014 Nov; 40(8):845-51. Epub 2014 Nov 13.
    View PubMed
  130. Wan SH, Liang JJ, Vaidya R, Blackshear JL, Chen D. Acquired Von Willebrand syndrome secondary to mitral and aortic regurgitation. Can J Cardiol. 2014 Sep; 30(9):1108.e9-1108.e10. Epub 2014 Feb 22.
    View PubMed
  131. Chen D, Ketterling RP. A leukemic presentation of a "triple-hit" lymphoma. Blood. 2014 Feb 20; 123 (8):1126
    View PubMed
  132. Tange JI, Grill D, Koch CD, Ybabez RJ, Krekelberg BJ, Fylling KA, Wiese CR, Baumann NA, Block DR, Karon BS, Chen D, Pruthi RK. Local verification and assignment of mean normal prothrombin time and International Sensitivity Index values across various instruments: recent experience and outcome from North America. Semin Thromb Hemost. 2014 Feb; 40(1):115-20. Epub 2013 Dec 31.
    View PubMed
  133. Pardanani A, Chen D, Abdelrahman RA, Reichard KK, Zblewski D, Wood AJ, McClure RF, Butterfield JH, Hanson CA, Tefferi A. Clonal mast cell disease not meeting WHO criteria for diagnosis of mastocytosis: clinicopathologic features and comparison with indolent mastocytosis. Leukemia 2013 Oct; 27 (10):2091-4 Epub 2013 July 30
    View PubMed
  134. Kourelis TV, Chen D, White JG, Gangat N, Uhl CB, Patnaik MM. Myeloid malignancy presenting with a platelet storage pool disorder. Leuk Lymphoma 2013 Aug; 54 (8):1800-1 Epub 2012 Dec 22
    View PubMed
  135. Li J, Chen H, Mariani A, Chen D, Klatt E, Podratz K, Drapkin R, Broaddus R, Dowdy S, Jiang SW. HE4 (WFDC2) Promotes Tumor Growth in Endometrial Cancer Cell Lines. Int J Mol Sci. 2013 Mar 15; 14(3):6026-43.
    View PubMed
  136. Blackshear JL, Wysokinska EM, Safford RE, Thomas CS, Stark ME, Shapiro BP, Ung S, Johns GS, Chen D. Indexes of von Willebrand factor as biomarkers of aortic stenosis severity (from the Biomarkers of Aortic Stenosis Severity [BASS] study). Am J Cardiol. 2013 Feb 1; 111 (3):374-81 Epub 2012 Nov 17
    View PubMed
  137. Chen D, Bachanova V, Ketterling RP, Begna KH, Hanson CA, Viswanatha DS. A case of nonleukemic myeloid sarcoma with FIP1L1-PDGFRA rearrangement: an unusual presentation of a rare disease. Am J Surg Pathol. 2013 Jan; 37: (1)147-51.
    View PubMed
  138. Chen D, Nichols WL. Von Willebrand disease testing repertoire: the past, present, and future. The Clotting Times (ECAT Foundation). Sep 2012(2):6-20.
  139. Joyce D, Crow S, Li Z, Joyce L, Milano C, Rogers J, Villamizar-Ortiz N, Chen D. Pilot investigation of a novel testing strategy for bleeding in ventricular assist device recipients. J Heart Lung Transplant. 2012 Jul; 31: (7)750-6.
    View PubMed
  140. He R, Chen D, He S. Factor XI: hemostasis, thrombosis, and antithrombosis. Thromb Res. 2012 May; 129(5):541-50. Epub 2011 Dec 22.
    View PubMed
  141. Ammash N, Konik EA, McBane RD, Chen D, Tange JI, Grill DE, Herges RM, McLeod TG, Friedman PA, Wysokinski WE. Left atrial blood stasis and Von Willebrand factor-ADAMTS13 homeostasis in atrial fibrillation. Arterioscler Thromb Vasc Biol. 2011 Nov; 31(11):2760-6.
    View PubMed
  142. Chen D, Tange JI, Meyers BJ, Pruthi RK, Nichols WL, Heit JA. Validation of an automated latex particle-enhanced immunoturbidimetric von Willebrand factor activity assay. J Thromb Haemost. 2011 Oct; 9 (10):1993-2002
    View PubMed
  143. Chen D, Ketterling RP, Hanson CA, Colgan JP, Zent CS, Viswanatha DS. A case of hairy cell leukemia with CCND1-IGH@ translocation: indolent non-nodal mantle cell lymphoma revisited. Am J Surg Pathol. 2011 Jul; 35(7):1080-4.
    View PubMed
  144. Patnaik MM, Lasho TL, Finke CM, Knudson RA, Ketterling RP, Chen D, Hoyer JD, Hanson CA, Tefferi A. Isolated del(5q) in myeloid malignancies: clinicopathologic and molecular features in 143 consecutive patients. Am J Hematol. 2011 May; 86 (5):393-8
    View PubMed
  145. Blackshear JL, Schaff HV, Ommen SR, Chen D, Nichols WL. Hypertrophic obstructive cardiomyopathy, bleeding history, and acquired von Willebrand syndrome: response to septal myectomy. Mayo Clin Proc. 2011 Mar; 86 (3):219-24
    View PubMed
  146. Pruthi RK, Daniels TM, Heit JA, Chen D, Owen WG, Nichols WL. Plasma von Willebrand factor multimer quantitative analysis by in-gel immunostaining and infrared fluorescent imaging. Thromb Res. 2010 Dec; 126 (6):543-9
    View PubMed
  147. Pereira NL, Chen D, Kushwaha SS, Park SJ. Discontinuation of antithrombotic therapy for a year or more in patients with continuous-flow left ventricular assist devices. Interact Cardiovasc Thorac Surg. 2010 Oct; 11 (4):503-5 Epub 2010 July 16
    View PubMed
  148. Crow S, Chen D, Milano C, Thomas W, Joyce L, Piacentino V 3rd, Sharma R, Wu J, Arepally G, Bowles D, Rogers J, Villamizar-Ortiz N. Acquired von Willebrand syndrome in continuous-flow ventricular assist device recipients. Ann Thorac Surg. 2010 Oct; 90 (4):1263-9; discussion 1269
    View PubMed
  149. Crow S, Milano C, Joyce L, Chen D, Arepally G, Bowles D, Thomas W, Ortiz NV. Comparative analysis of von Willebrand factor profiles in pulsatile and continuous left ventricular assist device recipients. ASAIO J. 2010 Sep-Oct; 56(5):441-5.
    View PubMed
  150. Patnaik MM, Lasho TL, Finke CM, Gangat N, Caramazza D, Holtan SG, Pardanani A, Knudson RA, Ketterling RP, Chen D, Hoyer JD, Hanson CA, Tefferi A. WHO-defined 'myelodysplastic syndrome with isolated del(5q)' in 88 consecutive patients: survival data, leukemic transformation rates and prevalence of JAK2, MPL and IDH mutations. Leukemia. 2010 Jul; 24 (7):1283-9 Epub 2010 May 20
    View PubMed
  151. Naina HV, Patnaik MM, Ali UA, Chen D, Ashrani AA. Systemic fibrinolysis caused by tissue plasminogen activator-producing metastatic breast cancer. J Clin Oncol. 2010 Apr 10; 28(11):e167-8. Epub 2010 Jan 11.
    View PubMed
  152. Kanehira K, Riegert-Johnson DL, Chen D, Gibson LE, Grinnell SD, Velgaleti GV. FISH diagnosis of acute graft-versus-host disease following living-related liver transplant. J Mol Diagn. 2009 Jul; 11 (4):355-8 Epub 2009 May 21
    View PubMed
  153. Morice WG, Chen D, Kurtin PJ, Hanson CA, McPhail ED. Novel immunophenotypic features of marrow lymphoplasmacytic lymphoma and correlation with Waldenstrom's macroglobulinemia. Mod Pathol. 2009 Jun; 22 (6):807-16 Epub 2009 Mar 13
    View PubMed
  154. Chen D, Law ME, Theis JD, Gamez JD, Caron LB, Vrana JA, Dogan A. Clinicopathologic features of CDK6 translocation-associated B-cell lymphoproliferative disorders. Am J Surg Pathol. 2009 May; 33 (5):720-9
    View PubMed
  155. Chen D, Hoyer JD, Ketterling RP, Tefferi A, Steensma DP, Holtan SG, Santana-Davila R, Porrata LF, Dewald GW, Hanson CA. Dysgranulopoiesis is an independent adverse prognostic factor in chronic myeloid disorders with an isolated interstitial deletion of chromosome 5q. Leukemia 2009 Apr; 23 (4):796-800 Epub 2008 Oct 23
    View PubMed
  156. Rumilla K, Chen D, Baudhuin LM. Pharmacogenetics in hemostasis: friend or foe? Semin Thromb Hemost. 2009 Feb; 35(1):42-9 Epub 2009 Mar 23.
    View PubMed
  157. Santana-Davila R, Tefferi A, Holtan SG, Ketterling RP, Dewald GW, Knudson RA, Steensma DP, Chen D, Hoyer JD, Hanson CA. Primary myelofibrosis is the most frequent myeloproliferative neoplasm associated with del(5q): clinicopathologic comparison of del(5q)-positive and -negative cases. Leuk Res. 2008 Dec; 32(12):1927-30. Epub 2008 Jun 09.
    View PubMed
  158. Holtan SG, Santana-Davila R, Dewald GW, Khetterling RP, Knudson RA, Hoyer JD, Chen D, Hanson CA, Porrata L, Tefferi A, Steensma DP. Myelodysplastic syndromes associated with interstitial deletion of chromosome 5q: clinicopathologic correlations and new insights from the pre-lenalidomide era. Am J Hematol. 2008 Sep; 83(9):708-13.
    View PubMed
  159. Pommer MS, Zhang Y, Keerthi N, Chen D, Thomson JA, Meinhart CD, Soh HT. Dielectrophoretic separation of platelets from diluted whole blood in microfluidic channels. Electrophoresis. 2008 Mar; 29(6):1213-8.
    View PubMed
  160. Chen D, Daigh CA, Chen D, Hendricksen JI, Pruthi RK, Nichols WL, Heit JA, Owen WG. A highly-sensitive plasma von Willebrand factor ristocetin cofactor (VWF:RCo) activity assay by flow cytometry. J Thromb Haemost. 2008 Feb; 6 (2):323-30 Epub 2007 Nov 20
    View PubMed
  161. Chen D, Wang P, Lewis RL, Daigh CA, Ho C, Chen X, Thomson JA, Kendziorski C. A microarray analysis of the emergence of embryonic definitive hematopoiesis. Exp Hematol. 2007 Sep; 35(9):1344-57.
    View PubMed
  162. Chen D, Lewis RL, Kaufman DS. Mouse and human embryonic stem cell models of hematopoiesis: past, present, and future. Biotechniques. 2003 Dec; 35(6):1253-61.
    View PubMed
  163. Chen D, Xu W, He P, Medrano EE, Whiteheart SW. Gaf-1, a gamma -SNAP-binding protein associated with the mitochondria. J Biol Chem. 2001 Apr 20; 276(16):13127-35. Epub 2001 Jan 25.
    View PubMed
  164. Chen D, Lemons PP, Schraw T, Whiteheart SW. Molecular mechanisms of platelet exocytosis: role of SNAP-23 and syntaxin 2 and 4 in lysosome release. Blood. 2000 Sep 1; 96(5):1782-8.
    View PubMed
  165. Chen D, Bernstein AM, Lemons PP, Whiteheart SW. Molecular mechanisms of platelet exocytosis: role of SNAP-23 and syntaxin 2 in dense core granule release. Blood. 2000 Feb 1; 95(3):921-9.
    View PubMed
  166. Lemons PP, Chen D, Whiteheart SW. Molecular mechanisms of platelet exocytosis: requirements for alpha-granule release. Biochem Biophys Res Commun. 2000 Jan 27; 267: (3)875-80.
    View PubMed
  167. He P, Southard RC, Chen D, Whiteheart SW, Cooper RL. Role of alpha-SNAP in promoting efficient neurotransmission at the crayfish neuromuscular junction. J Neurophysiol. 1999 Dec; 82(6):3406-16.
    View PubMed
  168. Chen D, Minger SL, Honer WG, Whiteheart SW. Organization of the secretory machinery in the rodent brain: distribution of the t-SNAREs, SNAP-25 and SNAP-23. Brain Res. 1999 Jun 12; 831(1-2):11-24.
    View PubMed
  169. Chen D, Whiteheart SW. Endosomal localization of SNAP-23 in HepG2 Cells. Biochem Biophy Res Commun. 1999; 252(2):340-6.
  170. Leung SM, Chen D, DasGupta BR, Whiteheart SW, Apodaca G. SNAP-23 requirement for transferrin recycling in Streptolysin-O-permeabilized Madin-Darby canine kidney cells. J Biol Chem. 1998 Jul 10; 273(28):17732-41.
    View PubMed
  171. Lemons PP, Chen D, Bernstein AM, Bennett MK, Whiteheart SW. Regulated secretion in platelets: identification of elements of the platelet exocytosis machinery. Blood. 1997 Aug 15; 90(4):1490-500.
    View PubMed
  172. Dean WL, Chen D, Brandt PC, Vanaman TC. Regulation of platelet plasma membrane Ca2+-ATPase by cAMP-dependent and tyrosine phosphorylation. J Biol Chem. 1997 Jun 13; 272(24):15113-9.
    View PubMed
  173. Wei D, Chen D. Screening of new genes with iluminochemistry method. Clinic and Basic Medicine. 1993; 13(5):76-80.
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