Publications Print Herndon J, Gupta N, Davidge-Pitts C, Imhof N, Gonzalez C, Carlson S, Will M, Martinez-Jorge J, Fahradyan V, Tamire L, Lin A, Nippoldt TB, Chang AY. Genital Surgery Outcomes Using an Individualized Algorithm for Hormone Management in Transfeminine Individuals. J Clin Endocrinol Metab. 2024 Oct 15; 109 (11):2774-2783 View PubMed Chang AY, Asokan AK, Lalia AZ, Sakrikar D, Lanza IR, Petterson XM, Nair KS. Insulin Regulation of Lysine and a-Aminoadipic Acid Dynamics and Amino Metabolites in Women With and Without Insulin Resistance. Diabetes. 2024 Oct 01; 73(10):1592-1604. View PubMed Sanchez-Garavito JE, Perez-Vega C, Iyer H, Rios-Zermeno J, Martinez GN, Navarro Garcia de Llano JP, Chang AY, Donaldson AM, Olomu OU, Chaichana KL, Quinones-Hinojosa A, Almeida JP, Samson SL. Implementation of a Standardized Interdisciplinary Perioperative Protocol for Patients Undergoing Transsphenoidal Surgery: Impact on Patient Outcomes. World Neurosurg. 2024 Oct; 190:e331-e340 Epub 2024 July 30 View PubMed Huang Y, Loo NM, Chang AY, Yu Z, McKenna AL, Ritchie C, Metcalfe AM, Nakhleh RE, Krishna M, Taner CB, Yang L. Hepatic Adenomatosis in a Transgender Man on Gender-Affirming Testosterone Therapy. ACG Case Rep J. 2024 Sep; 11 (9):e01483 Epub 2024 Sept 11 View PubMed Hong S, Shinya Y, Trejo-Lopez JA, Gruber LM, Erickson D, Bendok BR, Chaichana KL, Atkinson JL, Marino MJ, Donaldson AM, Stokken JK, Westphal SA, Chang AY, Samson SL, Choby GW, Van Gompel JJ. The clinical presentation of PIT1 positive pituitary neuroendocrine tumor immunonegative for growth hormone, prolactin, and thyroid stimulating hormone with analysis of clinical and immunostaining dissociation. Clin Neurol Neurosurg. 2024 Jan; 236:108075 Epub 2023 Nov 30 View PubMed Chang AY. . Elsevier: Clinical Overview: Female Hypogonadism ClinicalKey website. https://www.clinicalkey.com/#!/content/clinical_overview/67-s2.0-V2059.. 2023. Tannock LR, Weber TJ, Carranza BG, Chang AY, Clines G, Diab DL, Ehrhardt NM, Esfandiari NH, Grossmann M, Gurnell M, Mayson SE, Pantalone KM, Reddy D, Salvatori R, Shah M, Sidhaye AR, Turcu AF. ESAP 2023: Endocrine Self-Assessment Program. Washington, DC: Endocrine Society; 2023. Endocrine Self-Assessment Program. 2023. Hurtado Andrade MD, Tama E, Atkinson JLD, Chang AY. A False Pituitary Tumor. JCEM Case Rep. 2023 May; 1 (3):luad054 Epub 2023 June 01 View PubMed Herndon JS, Maheshwari AK, Nippoldt TB, Carlson SJ, Davidge-Pitts CJ, Chang AY. Comparison of the Subcutaneous and Intramuscular Estradiol Regimens as Part of Gender-Affirming Hormone Therapy. Endocr Pract. 2023 May; 29 (5):356-361 Epub 2023 Mar 01 View PubMed Naser JA, Lopez-Jimenez F, Chang AY, Baez-Suarez A, Attia ZI, Pislaru SV, Pellikka PA, Lin G, Kapa S, Friedman PA, Noseworthy PA. Artificial Intelligence-Augmented Electrocardiogram in Determining Sex: Correlation with Sex Hormone Levels. Mayo Clin Proc. 2023 Apr; 98 (4):541-548 Epub 2023 Feb 01 View PubMed Poojary PS, Nayak G, Panchanan G, Rao A, Kundapur SD, Kalthur SG, Mutalik S, Adiga SK, Zhao Y, Bakkum-Gamez J, Chang AY, DeStephano C, Sherman M, Kannan N, Kalthur G. Distinctions in PCOS Induced by Letrozole Vs Dehydroepiandrosterone With High-fat Diet in Mouse Model. Endocrinology. 2022 Sep 1; 163 (9) View PubMed Oberhelman-Eaton S, Chang A, Gonzalez C, Braith A, Singh RJ, Lteif A. Initiation of Gender-Affirming Testosterone Therapy in a Lactating Transgender Man. J Hum Lact. 2022 May; 38 (2):339-343 Epub 2021 Sept 07 View PubMed Tannock LR, Carranza BG, Chang AY, Diab DL, Ehrhardt NM, Esfandiari NH, Grossmann M, Gurnell M, Mayson SE, Pantalone KM, Reddy D, Salvatori R, Shah M, Sidhaye A, Vaidya A, Weber TJ. ESAP 2022: Endocrine Self-Assessment Program Washington, DC: Endocrine Society; 2022. 2022. Tannock LR, Carranza BG, Chang AY, Diab DL, Esfandiari NH, Grossmann M, Gurnell M, Magill SB, Mayson SE, Pantalone KM, Reddy D, Salvatori R, Sidhaye A, Subramanian S, Vaidya A, Weber TJ. ESAP 2021: Endocrine Self-Assessment Program Washington, DC: Endocrine Society. 2021. Kohlenberg J, Chang AY. Diffuse Wide Inflammatory Striae as the Presenting Symptom of Cushing Disease in a Young Adult. Mayo Clin Proc. 2021 Mar; 96 (3):529-530 View PubMed Gruber LM, Nanda S, Nippoldt T, Chang AY, Bancos I. Secondary Adrenal Insufficiency and Growth Hormone Deficiency in Patients with Fibromyalgia. J Pain Res. 2021; 14:1323-1329 Epub 2021 May 19 View PubMed Chang AY, Mirfakhraee S, King EE, Mercado JU, Donegan DM, Yuen KC. Mifepristone as Bridge or Adjunct Therapy in the Management of Challenging Cushing Disease Cases. Clin Med Insights Endocrinol Diabetes. 2021; 14:1179551421994102 Epub 2021 Mar 04 View PubMed James HA, Chang AY, Imhof RL, Sahoo A, Montenegro MM, Imhof NR, Gonzalez CA, Lteif AN, Nippoldt TB, Davidge-Pitts CJ. A community-based study of demographics, medical and psychiatric conditions, and gender dysphoria/incongruence treatment in transgender/gender diverse individuals. Biol Sex Differ. 2020 Oct 6; 11 (1):55 Epub 2020 Oct 06 View PubMed El-Maouche D, Merke DP, Vogiatzi MG, Chang AY, Turcu AF, Joyal EG, Lin VH, Weintraub L, Plaunt MR, Mohideen P, Auchus RJ. A Phase 2, Multicenter Study of Nevanimibe for the Treatment of Congenital Adrenal Hyperplasia. J Clin Endocrinol Metab. 2020 Aug 1; 105 (8) View PubMed Tannock LR, Carranza BG, Chang AY, Clement S, Diab DL, Esfandiari NH, Grossmann M, Gurnell M, Jonklaas J, Magill SB, Reddy D, Salvatori R, Sidhaye A, Subramanian S, Vaidya A, Weber TJ. ESAP 2020: Endocrine Self-Assessment Program. Washington, DC: Endocrine Society. 2020. Hughes JD, Young WF, Chang AY, Link MJ, Garces YI, Laack NN, Thompson GB, Pollock BE. Radiosurgical Management of Patients With Persistent or Recurrent Cushing Disease After Prior Transsphenoidal Surgery: A Management Algorithm Based on a 25-Year Experience. Neurosurgery. 2020 Apr 1; 86 (4):557-564 View PubMed Rocco R, Murphy BL, Patel VP, Hamidi O, Chang AY, Lyden ML. A rare case of a 65 year old female with a mesenteric paraganglioma Human Pathology: Case Reports. 2020; 19. Epub 2019 Dec 18. Heidari B, Lerman A, Lalia AZ, Lerman LO, Chang AY. Effect of Metformin on Microvascular Endothelial Function in Polycystic Ovary Syndrome. Mayo Clin Proc. 2019 Dec; 94 (12):2455-2466 View PubMed Tannock LR, Boelart K, Carranza Leon , BG, Chang AY, Clement S, Diab DL, Freel M, Irwig MS, Jonklaas J, Magill SB, Reddy D, Salvatori R, Sidhaye A, Subramanian S, Vaidya A, Weber TJ. ESAP 2019: Endocrine Self-Assessment Program. Washington, DC: Endocrine Society; 2019.. 2019. Wiencek JR, McCartney CR, Chang AY, Straseski JA, Auchus RJ, Woodworth A. Challenges in the Assessment and Diagnosis of Polycystic Ovary Syndrome. Clin Chem 2019 Mar; 65 (3):370-377 Epub 2019 Jan 03 View PubMed Krug RG 2nd, Chang AY, Raghunathan A, Van Gompel JJ. Apoplectic Silent Crooke Cell Adenoma with Adjacent Pseudoaneurysms: Causation or Bystander? World Neurosurg. 2019 Feb; 122:480-484 Epub 2018 Nov 19 View PubMed Sharma A, Kapoor E, Singh RJ, Chang AY, Erickson D. Diagnostic Thresholds for Androgen-Producing Tumors or Pathologic Hyperandrogenism in Women by Use of Total Testosterone Concentrations Measured by Liquid Chromatography-Tandem Mass Spectrometry. Clin Chem. 2018 Nov; 64 (11):1636-1645 Epub 2018 Aug 01 View PubMed Boumosleh JM, Grundy SM, Phan J, Neeland IJ, Chang AY, Vega GL. Metabolic Concomitants of Obese and Nonobese Women With Features of Polycystic Ovarian Syndrome Journal of the Endocrine Society.2017;1:(12):1417-1427. Chang AY, Lalia AZ, Jenkins GD, Dutta T, Carter RE, Singh RJ, Nair KS. Combining a nontargeted and targeted metabolomics approach to identify metabolic pathways significantly altered in polycystic ovary syndrome. Metabolism. 2017 Jun; 71:52-63 Epub 2017 Mar 08 View PubMed Chang AY, Oshiro J, Ayers C, Auchus RJ. Influence of race/ethnicity on cardiovascular risk factors in polycystic ovary syndrome, the Dallas Heart Study. Clin Endocrinol (Oxf). 2016 Jul; 85 (1):92-9 Epub 2015 Dec 24 View PubMed Natt N, Chang AY, Berbari EF, Kennel KA, Kearns AE. SELECTION OF ENDOCRINOLOGY SUBSPECIALTY TRAINEES: WHICH APPLICANT CHARACTERISTICS ARE ASSOCIATED WITH PERFORMANCE DURING FELLOWSHIP TRAINING? Endocr Pract. 2016 Jan; 22: (1)45-50. View PubMed Regensteiner JG, Golden S, Huebschmann AG, Barrett-Connor E, Chang AY, Chyun D, Fox CS, Kim C, Mehta N, Reckelhoff JF, Reusch JE, Rexrode KM, Sumner AE, Welty FK, Wenger NK, Anton B, American Heart Association Diabetes Committee of the Council on Lifestyle and Cardiometabolic Health, Council on Epidemiology and Prevention, Council on Functional Genomics and Translational Biology, and Council on Hypertension. Sex Differences in the Cardiovascular Consequences of Diabetes Mellitus: A Scientific Statement From the American Heart Association. Circulation. 2015 Dec 22; 132: (25)2424-47. View PubMed Javed A, Lteif AN, Kumar S, Simmons PS, Chang AY. Fasting Glucose Changes in Adolescents with Polycystic Ovary Syndrome Compared with Obese Controls: A Retrospective Cohort Study. J Pediatr Adolesc Gynecol. 2015 Dec; 28 (6):451-6 Epub 2015 Jan 07 View PubMed De Ycaza AE, Chang AY, Jensen JR, Khan Z, Erickson D. Approach to the management of rare clinical presentations of macroprolactinomas in reproductive-aged women. Case Rep Womens Health. 2015 Oct; 8:9-12 Epub 2015 Sept 24 View PubMed Maroules CD, Chang AY, Kotys-Traughber MS, Peshock RM. Coronary Endothelial Dysfunction in Women With Type 2 Diabetes Measured by Coronary Phase Contrast Flow Velocity Magnetic Resonance Imaging. J Investig Med. 2015 Oct; 63 (7):856-61 View PubMed Guo Q, Erickson BJ, Chang AY, Erickson D. Characteristics of dynamic magnetic resonance image enhancement in prolactinomas resistant to dopamine agonist therapy. J Investig Med. 2015 Mar; 63 (3):529-33 View PubMed Auchus RJ, Buschur EO, Chang AY, Hammer GD, Ramm C, Madrigal D, Wang G, Gonzalez M, Xu XS, Smit JW, Jiao J, Yu MK. Abiraterone acetate to lower androgens in women with classic 21-hydroxylase deficiency. J Clin Endocrinol Metab. 2014 Aug; 99 (8):2763-70 Epub 2014 Apr 29 View PubMed Neeland IJ, Winders BR, Ayers CR, Das SR, Chang AY, Berry JD, Khera A, McGuire DK, Vega GL, de Lemos JA, Turer AT. Higher natriuretic peptide levels associate with a favorable adipose tissue distribution profile. J Am Coll Cardiol. 2013 Aug 20; 62(8):752-60. Epub 2013 Apr 16. View PubMed Chang AY, Ayers C, Minhajuddin A, Jain T, Nurenberg P, de Lemos JA, Wild RA, Auchus RJ. Polycystic ovarian syndrome and subclinical atherosclerosis among women of reproductive age in the Dallas heart study. Clin Endocrinol (Oxf). 2011 Jan; 74(1):89-96. View PubMed Banks K, Puttagunta D, Murphy S, Lo M, McGuire DK, de Lemos JA, Chang AY, Grundy SM, Khera A. Clinical characteristics, vascular function, and inflammation in women with angina in the absence of coronary atherosclerosis: the Dallas Heart Study. JACC Cardiovasc Imaging. 2011 Jan; 4(1):65-73. View PubMed Maroules CD, Chang AY, Kontak A, Dimitrov I, Kotys M, Peshock RM. Measurement of coronary flow response to cold pressor stress in asymptomatic women with cardiovascular risk factors using spiral velocity-encoded cine MRI at 3 Tesla. Acta Radiol. 2010 May; 51(4):420-6. View PubMed Auchus RJ, Chang AY. 46,XX DSD: the masculinised female. Best Pract Res Clin Endocrinol Metab. 2010 Apr; 24(2):219-42. View PubMed Chang AY, FitzGerald SJ, Cannaday J, Zhang S, Patel A, Palmer MD, Reddy GP, Ordovas KG, Stillman AE, Janowitz W, Radford NB, Roberts AJ, Levine BD. Cardiovascular risk factors and coronary atherosclerosis in retired National Football League players. Am J Cardiol. 2009 Sep 15; 104(6):805-11. Epub 2009 Jul 18. View PubMed Chang AY, Wild RA. Characterizing cardiovascular risk in women with polycystic ovary syndrome: more than the sum of its parts? Semin Reprod Med. 2009 Jul; 27(4):299-305. Epub 2009 Jun 15. View PubMed Chang AY, Ghayee HK, Auchus RJ. Dehydroepiandrosterone replacement therapy--panacea, snake oil, or a bit of both? Nat Clin Pract Endocrinol Metab. 2008 Aug; 4(8):442-3. Epub 2008 Jun 17. View PubMed Patel R, Peterson G, Rohatgi A, Ghayee HK, Keeley EC, Auchus RJ, Chang AY. Hyperthyroidism-associated coronary vasospasm with myocardial infarction and subsequent euthyroid angina. Thyroid. 2008 Feb; 18(2):273-6. View PubMed Mitchell I, Livingston EH, Chang AY, Holt S, Snyder WH, Lingvay I, Nwariaku FE. Trends in thyroid cancer demographics and surgical therapy in the United States. Surgery. 2007 Dec; 142(6):823-8; discussion 828.e1. View PubMed Mitchell IC, Auchus RJ, Juneja K, Chang AY, Holt SA, Snyder WH, Nwariaku FE. "Subclinical Cushing's syndrome" is not subclinical: improvement after adrenalectomy in 9 patients. Surgery. 2007 Dec; 142(6):900-5; discussion 905.e1. View PubMed Chang AY, Abdullah SM, Jain T, Stanek HG, Das SR, McGuire DK, Auchus RJ, de Lemos JA. Associations among androgens, estrogens, and natriuretic peptides in young women: observations from the Dallas Heart Study. J Am Coll Cardiol. 2007 Jan 2; 49(1):109-16. Epub 2006 Nov 13. View PubMed Chang AY, Schneider JW. Inpatient Evaluation and Management of Congestive Heart Failure. Journal of Clinical Outcomes Management. 2003; 10(4):231-239. Schneider JW, Chang AY, Garratt A. Trastuzumab cardiotoxicity: Speculations regarding pathophysiology and targets for further study. Semin Oncol. 2002 Jun; 29(3 Suppl 11):22-8. View PubMed Chang AY, McKean SC. History of the Brigham and Women's Hospitalist Service. The Hospitalist. 2002; 6(3):23-25. Schneider JW, Chang AY, Rocco TP. Cardiotoxicity in signal transduction therapeutics: erbB2 antibodies and the heart. Semin Oncol. 2001 Oct; 28(5 Suppl 16):18-26. View PubMed Yao X, Chang AY, Boulpaep EL, Segal AS, Desir GV. Molecular cloning of a glibenclamide-sensitive, voltage-gated potassium channel expressed in rabbit kidney. 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