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Paul D. Brown, M.D.

  1. Radiation Oncologist
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Publications

  1. Vora S, Pafundi D, Voss M, Buras M, Ashman J, Bendok B, Breen W, Hu L, Kizilbash S, Laack N, Liu W, Mahajan A, Mrugala M, Porter A, Ruff M, Sio T, Uhm J, Yang M, Brinkmann D, Brown P. Short-course hypofractionated proton beam therapy, incorporating (18)F-DOPA PET and contrast-enhanced MRI targeting, for patients aged 65 years and older with newly diagnosed glioblastoma: a single-arm phase 2 trial. Lancet Oncol. 2024 Nov 18 [Epub ahead of print]
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  2. Morshed RA, Khandalavala KR, Dornhoffer JR, Babajanian EE, Daher GS, Marinelli JP, Brown PD, Lohse CM, Carlson ML, Link MJ. Minimum cochlear dose impacts hearing after radiosurgery for sporadic vestibular schwannoma. J Neurosurg. 2024 Nov 15; 1-8 [Epub ahead of print]
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  3. Levy A, Rusthoven CG, Brown PD, Le Pechoux C, Faivre-Finn C. PCI for Patients with Small Cell Lung Cancer: A New Perspective in the Immunotherapy Era. J Thorac Oncol. 2024 Nov 15 [Epub ahead of print]
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  4. Kotecha R, La Rosa A, Brown PD, Vogelbaum MA, Navarria P, Bodensohn R, Niyazi M, Karschnia P, Minniti G. Multidisciplinary management strategies for recurrent brain metastasis after prior radiotherapy: An overview. Neuro Oncol. 2024 Nov 4 Epub 2024 Nov 04
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  5. Eschbacher KL, Tran QT, Moskalev EA, Jenkins S, Fritchie K, Stoehr R, Caron A, Link MJ, Brown PD, Guajardo A, Brat DJ, Wu A, Santagata S, Louis DN, Brastianos PK, Kaplan AB, Alexander B, Rossi S, Ferrarese F, Raleigh DR, Nguyen MP, Gross J, Velazquez Vega J, Rodriguez F, Perry A, Martinez-Lage M, Orr BA, Haller F, Giannini C. NAB2::STAT6 fusions and genome-wide DNA methylation profiling: Predictors of patient outcomes in meningeal solitary fibrous tumors. Brain Pathol. 2024 Nov; 34 (6):e13256 Epub 2024 Mar 24
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  6. Vora SA, Pafundi DH, DeWees TA, Voss MM, Ashman JB, Bendok BR, Laack NN, Liu W, Mahajan A, Mrugala MM, Porter AB, Sio TT, Uhm JH, Yang M, Brinkmann DH, Brown PD. Short-Course, Hypofractionated Proton Beam Therapy Incorporating 18F-DOPA PET–MRI for Older Patients With Newly Diagnosed Glioblastoma: A Prospective Phase 2 Trial The Lancet Oncology (Manuscript accepted pending revisions-24-00665R2). 2024.
  7. Kinslow CJ, Roy S, Iwamoto FM, Brown PD, DeStephano DM, Canoll PD, Qureshi SS, Gallito M, Sisti MB, Bruce JN, Horowitz DP, Kachnic LA, Neugut AI, Yu JB, Mehta MP, Cheng SK, Wang TJC. The IDH paradox: Meta-analysis of alkylating chemotherapy in IDH-wild type and -mutant lower grade gliomas. Neuro Oncol. 2024 Oct 3; 26 (10):1839-1849
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  8. Florez MA, De B, Kowalchuk R, Tang C, Bishop AJ, Kouzy R, Amini B, Briere T, Beckham TH, Wang C, Li J, Tatsui CE, Rhines LD, Brown PD, Merrell K, Ghia AJ. Validation of the prognostic index for spine metastasis (PRISM) for stratifying survival in patients treated with spinal stereotactic body radiation. Radiother Oncol. 2024 Oct 2; 201:110570 Epub 2024 Oct 02
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  9. Gunn HJ, Zaniletti I, Breen WG, Leavitt T, Bogan A, Mahajan A, Brown PD, Yan E, Vora SA, Merrell KW, Ashman JB, Peterson JL, Leenstra JL, Wilson ZC, Laughlin BS, Laack NN, DeWees TA. Establishing the minimal clinically important difference of the Brief Fatigue Inventory for brain or CNS cancer patients undergoing radiotherapy. Neurooncol Pract. 2024 Oct; 11 (5):633-639 Epub 2024 Apr 27
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  10. Vora SA, Pafundi DH, Voss MM, Buras MR, Ashman JB, Bendok BR, Breen W, Hu LS, Kizilbash SH, Laack NN, Liu W, Mahajan A, Mrugala MM, Porter Umphrey AB, Ruff MW, Sio TT, Uhm J, Yang M, Brinkmann DH, Brown PD. Phase 2 Study of Short-Course, Hypofractionated Proton Beam Therapy Incorporating 18F-DOPA PET–MRI for Older Patients With Newly Diagnosed Glioblastoma (In review with Editor, Manuscript Number: D-24-00665R1) The Lancet. 2024.
  11. El-Hajj VG, Ghaith AK, Hoang H, Nguyen RH, Al-Saidi NN, Graepel SP, Atallah E, Elmi-Terander A, Lehrer EJ, Brown PD, Bydon M. Impact of proton versus photon adjuvant radiotherapy on overall survival in the management of skull base and spinal chordomas: a National Cancer Database analysis. J Neurosurg. 2024 Aug 23; 1-9 [Epub ahead of print]
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  12. Frechette KM, Breen WG, Brown PD, Sener UT, Webb LM, Routman DM, Laack NN, Mahajan A, Lehrer EJ. Radiotherapy and Systemic Treatment for Leptomeningeal Disease. Biomedicines. 2024 Aug 7; 12 (8) Epub 2024 Aug 07
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  13. Lehrer EJ, Breen WG, Singh R, Palmer JD, Brown PD, Trifiletti DM, Sheehan JP. Hypofractionated Stereotactic Radiosurgery in the Management of Brain Metastases. Neurosurgery. 2024 Aug 1; 95 (2):253-258 Epub 2024 Mar 21
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  14. Kotecha R, Schiff D, Chakravarti A, Fleming JL, Brown PD, Puduvalli VK, Vogelbaum MA, Gondi V, Gallus M, Okada H, Mehta MP. Multidisciplinary Management of Isocitrate Dehydrogenase-Mutated Gliomas in a Contemporary Molecularly Defined Era. J Clin Oncol. 2024 Jul 20; 42 (21):2588-2598 Epub 2024 June 04
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  15. Wefel JS, Deshmukh S, Brown PD, Grosshans DR, Sulman EP, Cerhan JH, Mehta MP, Khuntia D, Shi W, Mishra MV, Suh JH, Laack NN, Chen Y, Curtis AA, Laba JM, Elsayed A, Thakrar A, Pugh SL, Bruner DW. Impact of Apolipoprotein E Genotype on Neurocognitive Function in Patients With Brain Metastases: An Analysis of NRG Oncology's RTOG 0614. Int J Radiat Oncol Biol Phys. 2024 Jul 1; 119 (3):846-857 Epub 2023 Dec 13
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  16. Cherng HR, Qu M, Zafari Z, Bentzen SM, Armstrong TS, Gondi V, Brown PD, Mehta M, Mishra MV. Evaluating the sensitivity of EQ-5D-5L in patients with brain metastases: a secondary analysis of NRG CC001. J Natl Cancer Inst. 2024 Jun 7; 116 (6):983-989
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  17. Kowalchuk RO, Mullikin TC, Spears GM, Johnson-Tesch BA, Rose PS, Siontis BL, Kun Kim D, Costello BA, Morris JM, Gao RW, Shiraishi S, Lucido JJ, Olivier KR, Owen D, Stish BJ, Waddle MR, Laack NN, Park SS, Brown PD, Merrell KW. Assessment of minimum target dose as a predictor of local failure after spine SBRT. Radiother Oncol. 2024 Jun; 195:110260 Epub 2024 Mar 27
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  18. Cherng HR, Sun K, Bentzen S, Armstrong TS, Gondi V, Brown PD, Mehta M, Mishra MV. Evaluating the heterogeneity of hippocampal avoidant whole brain radiotherapy treatment effect: A secondary analysis of NRG CC001. Neuro Oncol. 2024 May 3; 26 (5):911-921
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  19. Carlstrom LP, Bauman MMJ, Oushy S, Perry A, Brown PD, Peris-Celda M, Van Gompel JJ, Graffeo CS, Link MJ. Lower Cranial Nerve Schwannomas: Cohort Study and Systematic Review. Neurosurgery. 2024 Apr 1; 94 (4):745-755 Epub 2023 Oct 24
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  20. Hong S, Bouchal SM, Bauman MMJ, Riviere-Cazaux C, Pumford AD, Brown PD, Yan ES, Stafford SL, Markovic SN, Link MJ, Burns TC, Jusue-Torres I, Pollock BE, Parney IF. The longitudinal risk of hemorrhage of melanoma brain metastases after Gamma Knife radiosurgery. J Neurosurg. 2024 Apr 1; 140 (4):938-948 Epub 2023 Sept 29
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  21. Routman DM, Jusue-Torres I, Brown PD, Trifiletti DM, Vora SA, Brown DA, Parney IF, Burns TC, Yan E. Pre-operative vs. post-operative stereotactic radiosurgery for operative metastatic brain tumors: study protocol for a phase III clinical trial. BMC Cancer. 2024 Mar 12; 24 (1):332
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  22. Miccio JA, Tian Z, Mahase SS, Lin C, Choi S, Zacharia BE, Sheehan JP, Brown PD, Trifiletti DM, Palmer JD, Wang M, Zaorsky NG. Estimating the risk of brain metastasis for patients newly diagnosed with cancer. Commun Med (Lond). 2024 Feb 22; 4 (1):27
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  23. Sener U, Webb M, Breen WG, Neth BJ, Laack NN, Routman D, Brown PD, Mahajan A, Frechette K, Dudek AZ, Markovic SN, Block MS, McWilliams RR, Dimou A, Kottschade LA, Montane HN, Kizilbash SH, Campian JL. Proton Craniospinal Irradiation with Immunotherapy in Two Patients with Leptomeningeal Disease from Melanoma. J Immunother Precis Oncol. 2024 Feb; 7 (1):1-6 Epub 2024 Feb 05
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  24. El-Hajj VG, Ghaith AK, Nguyen RH, Al-Saidi NN, Hoang H, Graepel SP, Elmi-Terander A, Lehrer EJ, Brown P, Bydon M. Analysis of demographics and the impact of adjuvant radiotherapy on a nationwide cohort of patients with high-grade spinal meningiomas. Neurooncol Adv. 2024 Jan-Dec; 6 (1):vdae018 Epub 2024 Feb 05
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  25. Breen WG, Geno CS, Waddle MR, Qian J, Harmsen WS, Burns TC, Sener UT, Ruff MW, Neth BJ, Uhm JH, Routman DM, Yan E, Kruse JJ, Laack NN, Brown PD, Mahajan A. Proton versus photon craniospinal irradiation for adult medulloblastoma: A dosimetric, toxicity, and exploratory cost analysis. Neurooncol Adv. 2024 Jan-Dec; 6 (1):vdae034 Epub 2024 Mar 08
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  26. Gondi V, Deshmukh S, Brown PD, Wefel JS, Armstrong TS, Tome WA, Gilbert MR, Konski A, Robinson CG, Bovi JA, Benzinger TLS, Roberge D, Kundapur V, Kaufman I, Shah S, Usuki KY, Baschnagel AM, Mehta MP, Kachnic LA. Sustained Preservation of Cognition and Prevention of Patient-Reported Symptoms With Hippocampal Avoidance During Whole-Brain Radiation Therapy for Brain Metastases: Final Results of NRG Oncology CC001. Int J Radiat Oncol Biol Phys. 2023 Nov 1; 117 (3):571-580 Epub 2023 May 06
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  27. Seaberg MH, Kazda T, Youland RS, Laack NN, Pafundi DH, Anderson SK, Sarkaria JN, Galanis E, Brown PD, Brinkmann DH. Dosimetric patterns of failure in the era of novel chemoradiotherapy in newly-diagnosed glioblastoma patients. Radiother Oncol. 2023 Nov; 188:109768 Epub 2023 June 28
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  28. Garg AK, Hernandez M, Schlembach PJ, Bowers JR, McAleer MF, Brown PD, Gopal R, Wiederhold L, Swanson T, Shah SJ, Li J, Ferguson SD, Philip NV, DeGracia L, Bloom ES, Chun SG. A phase II clinical trial of frameless, fractionated stereotactic radiation therapy for brain metastases. JNCI Cancer Spectr. 2023 Oct 31; 7 (6)
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  29. Garg AK, Hernandez M, Schlembach PJ, McAleer MF, Brown PD, Gopal RS, Wiederhold L, Swanson TA, Shah SJ, Li J, Ferguson S, Philip N, De Gracia B, Bloom E, Chun SG. Frameless Fractionated Linear Accelerator-Based Stereotactic Radiotherapy for Brain Metastases: Results of a Single-Arm Phase II Multi-Institutional Clinical Trial. Int J Radiat Oncol Biol Phys. 2023 Oct 1; 117 (2S):e94-e95
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  30. Rusthoven CG, Staley AW, Gao D, Yomo S, Bernhardt D, Wandrey N, El Shafie R, Kraemer A, Padilla O, Chiang V, Faramand AM, Palmer JD, Zacharia BE, Wegner RE, Hattangadi-Gluth JA, Levy A, Bernstein K, Mathieu D, Cagney DN, Chan MD, Grills IS, Braunstein S, Lee CC, Sheehan JP, Kluwe C, Patel S, Halasz LM, Andratschke N, Deibert CP, Verma V, Trifiletti DM, Cifarelli CP, Debus J, Combs SE, Sato Y, Higuchi Y, Aoyagi K, Brown PD, Alami V, Niranjan A, Lunsford LD, Kondziolka D, Camidge DR, Kavanagh BD, Robin TP, Serizawa T, Yamamoto M. Comparison of first-line radiosurgery for small-cell and non-small cell lung cancer brain metastases (CROSS-FIRE). J Natl Cancer Inst. 2023 Aug 8; 115 (8):926-936
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  31. Bloom JR, Hotca A, Cherry DR, Dickstein DR, Runnels J, Samstein RM, Veluswamy RR, Rosenzweig KE, Brown PD, Trifiletti DM, Palmer JD, Singh R, Breen WG, Lehrer EJ. The incorporation of cognitive-sparing techniques into prophylactic cranial irradiation in the management of small cell lung cancer. Chin Clin Oncol. 2023 Aug; 12 (4):44 Epub 2023 July 29
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  32. Brastianos PK, Twohy E, Geyer S, Gerstner ER, Kaufmann TJ, Tabrizi S, Kabat B, Thierauf J, Ruff MW, Bota DA, Reardon DA, Cohen AL, De La Fuente MI, Lesser GJ, Campian J, Agarwalla PK, Kumthekar P, Mann B, Vora S, Knopp M, Iafrate AJ, Curry WT Jr, Cahill DP, Shih HA, Brown PD, Santagata S, Barker FG 2nd, Galanis E. BRAF-MEK Inhibition in Newly Diagnosed Papillary Craniopharyngiomas. N Engl J Med. 2023 Jul 13; 389 (2):118-126
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  33. Huntoon K, Anderson SK, Ballman KV, Twohy E, Dooley K, Jiang W, An Y, Li J, von Roemeling C, Qie Y, Ross OA, Cerhan JH, Whitton AC, Greenspoon JN, Parney IF, Ashman JB, Bahary JP, Hadjipanayis C, Urbanic JJ, Farace E, Khuntia D, Laack NN, Brown PD, Roberge D, Kim BYS. Association of circulating markers with cognitive decline after radiation therapy for brain metastasis. Neuro Oncol. 2023 Jun 2; 25 (6):1123-1131
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  34. Kowalchuk RO, Trifiletti DM, Brown PD, Sheehan JP. Contemporary radiotherapy and radiosurgery techniques for refractory pituitary adenomas. Pituitary. 2023 Jun; 26 (3):298-302 Epub 2023 Feb 17
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  35. McGovern SL, Luo D, Johnson J, Nguyen K, Li J, McAleer MF, Yeboa D, Grosshans DR, Ghia AJ, Chung C, Bishop AJ, Song J, Thall PF, Brown PD, Mahajan A. A Prospective Study of Conventionally Fractionated Dose Constraints for Reirradiation of Primary Brain Tumors in Adults. Pract Radiat Oncol. 2023 May-Jun; 13 (3):231-238 Epub 2022 Dec 31
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  36. Kowalchuk RO, Mullikin TC, Florez M, De BS, Spears GM, Rose PS, Siontis BL, Kim DK, Costello BA, Morris JM, Marion JT, Johnson-Tesch BA, Gao RW, Shiraishi S, Lucido JJ, Trifiletti DM, Olivier KR, Owen D, Stish BJ, Waddle MR, Laack NN, Park SS, Brown PD, Ghia AJ, Merrell KW. Development and validation of a recursive partitioning analysis-based pretreatment decision-making tool identifying ideal candidates for spine stereotactic body radiation therapy. Cancer. 2023 Mar 15; 129(6):956-965. Epub 2022 Dec 26.
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  37. Naylor RM, Graffeo CS, Nesvick CL, Link MJ, Brown PD, Stafford SL, Laack NN, Pollock BE. Stereotactic radiosurgery for intermediate- and high-grade arteriovenous malformations: outcomes stratified by the supplemented Spetzler-Martin grading system. J Neurosurg. 2023 Mar 1; 138 (3):804-809 Epub 2022 July 08
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  38. Palmer JD, Prasad RN, Cioffi G, Kruchtko C, Zaorsky NG, Trifiletti DM, Gondi V, Brown PD, Perlow HK, Mishra MV, Chakravarti A, Barnholtz-Sloan JS, Ostrom QT. Exposure to radon and heavy particulate pollution and incidence of brain tumors. Neuro Oncol. 2023 Feb 14; 25 (2):407-417
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  39. Brastianos PK, Twohy EL, Gerstner ER, Kaufmann TJ, Iafrate AJ, Lennerz J, Jeyapalan S, Piccioni DE, Monga V, Fadul CE, Schiff D, Taylor JW, Chowdhary SA, Bettegowda C, Ansstas G, De La Fuente M, Anderson MD, Shonka N, Damek D, Carrillo J, Kunschner-Ronan LJ, Chaudhary R, Jaeckle KA, Senecal FM, Kaley T, Morrison T, Thomas AA, Welch MR, Iwamoto F, Cachia D, Cohen AL, Vora S, Knopp M, Dunn IF, Kumthekar P, Sarkaria J, Geyer S, Carrero XW, Martinez-Lage M, Cahill DP, Brown PD, Giannini C, Santagata S, Barker FG 2nd, Galanis E. Alliance A071401: Phase II Trial of Focal Adhesion Kinase Inhibition in Meningiomas With Somatic NF2 Mutations. J Clin Oncol. 2023 Jan 20; 41 (3):618-628 Epub 2022 Oct 26
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  40. Kowalchuk R, Mullikin TC, Breen W, Gits HC, Florez M, De B, Harmsen WS, Rose PS, Siontis BL, Costello BA, Morris JM, Lucido JJ, Olivier KR, Stish B, Laack NN, Park S, Owen D, Ghia AJ, Brown PD, Merrell KW. Development and validation of a unifying pre-treatment decision tool for intracranial and extracranial metastasis-directed radiotherapy. Front Oncol. 2023; 13:1095170 Epub 2023 Mar 27
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  41. Vaubel RA, Kumar R, Weiskittel TM, Jenkins S, Dasari S, Uhm JH, Lachance DH, Brown PD, Van Gompel JJ, Jenkins RB, Kipp BR, Sukov WR, Giannini C, Johnson DR, Raghunathan A. Genomic markers of recurrence risk in atypical meningioma following gross total resection. Neurooncol Adv. 2023 Jan-Dec; 5 (1):vdad004 Epub 2023 Jan 10
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  42. Palmer JD, Klamer BG, Ballman KV, Brown PD, Cerhan JH, Anderson SK, Carrero XW, Whitton AC, Greenspoon J, Parney IF, Laack NNI, Ashman JB, Bahary JP, Hadjipanayis CG, Urbanic JJ, Barker FG 2nd, Farace E, Khuntia D, Giannini C, Buckner JC, Galanis E, Roberge D. Association of Long-term Outcomes With Stereotactic Radiosurgery vs Whole-Brain Radiotherapy for Resected Brain Metastasis: A Secondary Analysis of The N107C/CEC.3 (Alliance for Clinical Trials in Oncology/Canadian Cancer Trials Group) Randomized Clinical Trial. JAMA Oncol. 2022 Dec 1; 8 (12):1809-1815
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  43. Kirkman MA, Day J, Gehring K, Zienius K, Grosshans D, Taphoorn M, Li J, Brown PD. Interventions for preventing and ameliorating cognitive deficits in adults treated with cranial irradiation. Cochrane Database Syst Rev. 2022 Nov 25; 11 (11):CD011335
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  44. Liang Y, Lee K, Bovi JA, Palmer JD, Brown PD, Gondi V, Tome WA, Benzinger TLS, Mehta MP, Li XA. Deep Learning-Based Automatic Detection of Brain Metastases in Heterogenous Multi-Institutional Magnetic Resonance Imaging Sets: An Exploratory Analysis of NRG-CC001. Int J Radiat Oncol Biol Phys. 2022 Nov 1; 114 (3):529-536 Epub 2022 July 02
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  45. Abraham CD, Pugh SL, Bovi JA, Gondi V, Mehta MP, Benzinger T, Owen CJ, Lo SS, Kundapur V, Brown PD, Sun AY, Howard SP, DeNittis AS, Robinson CG, Kachnic LA. Association of Pretreatment Hippocampal Volume With Neurocognitive Function in Patients Treated With Hippocampal Avoidance Whole Brain Radiation Therapy for Brain Metastases: Secondary Analysis of NRG Oncology/RTOG 0933. Adv Radiat Oncol. 2022 Nov-Dec; 7 (6):100859 Epub 2021 Dec 11
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  46. Webb M, Johnson DR, Mahajan A, Brown P, Neth B, Kizilbash SH, Sener U. Clinical experience and outcomes in patients with pineal parenchymal tumor of intermediate differentiation (PPTID): a single-institution analysis. J Neurooncol. 2022 Nov; 160 (2):527-534 Epub 2022 Oct 27
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  47. Aizer AA, Lamba N, Ahluwalia MS, Aldape K, Boire A, Brastianos PK, Brown PD, Camidge DR, Chiang VL, Davies MA, Hu LS, Huang RY, Kaufmann T, Kumthekar P, Lam K, Lee EQ, Lin NU, Mehta M, Parsons M, Reardon DA, Sheehan J, Soffietti R, Tawbi H, Weller M, Wen PY. Brain metastases: A Society for Neuro-Oncology (SNO) consensus review on current management and future directions. Neuro Oncol. 2022 Oct 3; 24 (10):1613-1646
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  48. Matsui JK, Perlow HK, Facer BD, McCalla A, Marrazzo L, Detti B, Scorsetti M, Clerici E, Scoccianti S, Navarria P, Trifiletti DM, Gondi V, Bovi J, Huang J, Brown PD, Palmer JD. Radiotherapy for elderly patients with glioblastoma: an assessment of hypofractionation and modern treatment techniques. Chin Clin Oncol. 2022 Oct; 11 (5):38
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  49. Hasanov E, Yeboa DN, Tucker MD, Swanson TA, Beckham TH, Rini B, Ene CI, Hasanov M, Derks S, Smits M, Dudani S, Heng DYC, Brastianos PK, Bex A, Hanalioglu S, Weinberg JS, Hirsch L, Carlo MI, Aizer A, Brown PD, Bilen MA, Chang EL, Jaboin J, Brugarolas J, Choueiri TK, Atkins MB, McGregor BA, Halasz LM, Patel TR, Soltys SG, McDermott DF, Elder JB, Baskaya MK, Yu JB, Timmerman R, Kim MM, Mut M, Markert J, Beal K, Tannir NM, Samandouras G, Lang FF, Giles R, Jonasch E. An interdisciplinary consensus on the management of brain metastases in patients with renal cell carcinoma. CA Cancer J Clin. 2022 Sep; 72 (5):454-489 Epub 2022 June 16
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  50. Sperduto PW, De B, Li J, Carpenter D, Kirkpatrick J, Milligan M, Shih HA, Kutuk T, Kotecha R, Higaki H, Otsuka M, Aoyama H, Bourgoin M, Roberge D, Dajani S, Sachdev S, Gainey J, Buatti JM, Breen W, Brown PD, Ni L, Braunstein S, Gallitto M, Wang TJC, Shanley R, Lou E, Shiao J, Gaspar LE, Tanabe S, Nakano T, An Y, Chiang V, Zeng L, Soliman H, Elhalawani H, Cagney D, Thomas E, Boggs DH, Ahluwalia MS, Mehta MP. Graded Prognostic Assessment (GPA) for Patients With Lung Cancer and Brain Metastases: Initial Report of the Small Cell Lung Cancer GPA and Update of the Non-Small Cell Lung Cancer GPA Including the Effect of Programmed Death Ligand 1 and Other Prognostic Factors. Int J Radiat Oncol Biol Phys. 2022 Sep 1; 114 (1):60-74 Epub 2022 Mar 21
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  51. Matsui JK, Perlow HK, Baiyee C, Ritter AR, Mishra MV, Bovi JA, Gondi V, Brown PD, Loughan AR, Leeper HE, Dawson E, Palmer JD. Quality of Life and Cognitive Function Evaluations and Interventions for Patients with Brain Metastases in the Radiation Oncology Clinic. Cancers (Basel). 2022 Sep 1; 14 (17) Epub 2022 Sept 01
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  52. Schiff D, Messersmith H, Brastianos PK, Brown PD, Burri S, Dunn IF, Gaspar LE, Gondi V, Jordan JT, Maues J, Mohile N, Redjal N, Stevens GHJ, Sulman EP, van den Bent M, Wallace HJ, Zadeh G, Vogelbaum MA. Radiation Therapy for Brain Metastases: ASCO Guideline Endorsement of ASTRO Guideline. J Clin Oncol. 2022 Jul 10; 40 (20):2271-2276 Epub 2022 May 13
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  53. Ramos-Fresnedo A, Domingo RA, Sanchez-Garavito JE, Perez-Vega C, Akinduro OO, Jentoft ME, Vora SA, Brown PD, Porter AB, Bendok BR, Link MJ, Middlebrooks EH, Trifiletti DM, Chaichana KL, Quinones-Hinojosa A, Sherman WJ. The impact of multiple lesions on progression-free survival of meningiomas: a 10-year multicenter experience. J Neurosurg. 2022 Jul 1; 137 (1):9-17 Epub 2021 Nov 19
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  54. Breen WG, Youland RS, Giri S, Jacobson SB, Pafundi DH, Brown PD, Hunt CH, Mahajan A, Ruff MW, Kizilbash SH, Uhm JH, Routman DM, Jones JE, Brinkmann DH, Laack NN. Initial results of a phase II trial of (18)F-DOPA PET-guided re-irradiation for recurrent high-grade glioma. J Neurooncol. 2022 Jul; 158 (3):323-330 Epub 2022 May 18
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  55. Gondi V, Bauman G, Bradfield L, Burri SH, Cabrera AR, Cunningham DA, Eaton BR, Hattangadi-Gluth JA, Kim MM, Kotecha R, Kraemer L, Li J, Nagpal S, Rusthoven CG, Suh JH, Tome WA, Wang TJC, Zimmer AS, Ziu M, Brown PD. Radiation Therapy for Brain Metastases: An ASTRO Clinical Practice Guideline. Pract Radiat Oncol. 2022 Jul-Aug; 12 (4):265-282 Epub 2022 May 06
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  56. Kowalchuk RO, Mullikin TC, Harmsen WS, Rose PS, Siontis BL, Kim DK, Costello BA, Morris JM, Marion JT, Johnson-Tesch BA, Gao RW, Shiraishi S, Lucido JJ, Olivier KR, Owen D, Stish BJ, Laack NN, Park SS, Brown PD, Merrell KW. Development and internal validation of a recursive partitioning analysis-based model predictive of pain flare incidence after spine stereotactic body radiation therapy. Practical Radiation Oncology. 2022 Jul-aug; 12 (4):E269-77
  57. Perlow HK, Prasad RN, Yang M, Klamer B, Matsui J, Marrazzo L, Detti B, Scorsetti M, Clerici E, Arnett A, Beyer S, Ammirati M, Chakravarti A, Raval RR, Brown PD, Navarria P, Scoccianti S, Grecula JC, Palmer JD. Accelerated hypofractionated radiation for elderly or frail patients with a newly diagnosed glioblastoma: A pooled analysis of patient-level data from 4 prospective trials. Cancer. 2022 Jun 15; 128 (12):2367-2374 Epub 2022 Mar 22
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  58. Chung C, Brown PD, Wefel JS. Lessons learned from proton vs photon radiation therapy for glioblastoma signal-finding trial. Neuro Oncol 2022 May 4; 24 (5):851
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  59. Teyateeti A, Graffeo CS, Perry A, Tryggestad EJ, Brown PD, Pollock BE, Link MJ. The Effect of Prescription Isodose Variation on Tumor Control and Toxicities in Stereotactic Radiosurgery for Sporadic Vestibular Schwannoma: Propensity Score-Matched Case-Control Study. J Neurol Surg B Skull Base. 2022 Apr; 83 (2):193-202 Epub 2021 Feb 18
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  60. Kowalchuk RO, Johnson-Tesch BA, Marion JT, Mullikin TC, Harmsen WS, Rose PS, Siontis BL, Kim DK, Costello BA, Morris JM, Gao RW, Shiraishi S, Lucido JJ, Sio TT, Trifiletti DM, Olivier KR, Owen D, Stish BJ, Waddle MR, Laack NN, Park SS, Brown PD, Merrell KW. Development and Assessment of a Predictive Score for Vertebral Compression Fracture After Stereotactic Body Radiation Therapy for Spinal Metastases. JAMA Oncol. 2022 Mar 01; 8(3):412-419.
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  61. Vogelbaum MA, Brown PD, Messersmith H, Brastianos PK, Burri S, Cahill D, Dunn IF, Gaspar LE, Gatson NTN, Gondi V, Jordan JT, Lassman AB, Maues J, Mohile N, Redjal N, Stevens G, Sulman E, van den Bent M, Wallace HJ, Weinberg JS, Zadeh G, Schiff D. Treatment for Brain Metastases: ASCO-SNO-ASTRO Guideline. J Clin Oncol. 2022 Feb 10; 40 (5):492-516 Epub 2021 Dec 21
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  62. Porter AB, Liu H, Kohli S, Cerhan JL, Sloan J, McMurray RP, Le-Rademacher J, Loprinzi CL, Villano JL, Kizilbash SH, Mehta MP, Jaeckle KA, Brown PD. Efficacy of Treatment With Armodafinil for Cancer-Related Fatigue in Patients With High-grade Glioma: A Phase 3 Randomized Clinical Trial. JAMA Oncol. 2022 Feb 1; 8 (2):259-267
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  137. Brigell RH, Cagney DN, Martin AM, Besse LA, Catalano PJ, Lee EQ, Wen PY, Brown PD, Phillips JG, Pashtan IM, Tanguturi SK, Haas-Kogan DA, Alexander BM, Aizer AA. Local control after brain-directed radiation in patients with cystic versus solid brain metastases. J Neurooncol. 2019 Apr; 142 (2):355-363 Epub 2019 Feb 04
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  140. Cerhan JH, Butts AM, Syrjanen JA, Aakre JA, Brown PD, Petersen RC, Jack CR Jr, Roberts RO. Factors Associated With Meningioma Detected in a Population-Based Sample. Mayo Clin Proc. 2019 Feb; 94 (2):254-261
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  145. Hall WA, Pugh SL, Wefel JS, Armstrong TS, Gilbert MR, Brachman DG, Werner-Wasik M, Wendland MM, Brown PD, Chao ST, Roof KS, Robins HI, Mehta MP, Curran WJ Jr, Movsas B. Influence of Residual Disease Following Surgical Resection in Newly Diagnosed Glioblastoma on Clinical, Neurocognitive, and Patient Reported Outcomes. Neurosurgery. 2019 Jan 1; 84 (1):66-76
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  147. Cerhan JH, Caine C, Anderson SK, Johnson DR, Lachance DH, Yan E, Brown PD. Preliminary exploration of a computerized cognitive battery and comparison with traditional testing in patients with high-grade glioma. Neurooncol Pract. 2019 Jan; 6 (1):71-77 Epub 2018 May 21
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  148. Ghia AJ, Guha-Thakurta N, Hess K, Yang JN, Settle SH, Sharpe HJ, Li J, McAleer M, Chang EL, Tatsui CE, Brown PD, Rhines LD. Phase 1 Study of Spinal Cord Constraint Relaxation With Single Session Spine Stereotactic Radiosurgery in the Primary Management of Patients With Inoperable, Previously Unirradiated Metastatic Epidural Spinal Cord Compression. Int J Radiat Oncol Biol Phys. 2018 Dec 1; 102 (5):1481-1488 Epub 2018 Aug 09
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  149. Sperduto PW, Deegan BJ, Li J, Jethwa KR, Brown PD, Lockney N, Beal K, Rana NG, Attia A, Tseng CL, Sahgal A, Shanley R, Sperduto WA, Lou E, Zahra A, Buatti JM, Yu JB, Chiang V, Molitoris JK, Masucci L, Roberge D, Shi DD, Shih HA, Olson A, Kirkpatrick JP, Braunstein S, Sneed P, Mehta MP. Estimating survival for renal cell carcinoma patients with brain metastases: an update of the Renal Graded Prognostic Assessment tool. Neuro Oncol. 2018 Nov 12; 20(12):1652-1660.
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  150. Stoker J, Vora S, Patel A, Grosshans D, Brown PD, Vern-Gross T, Bues M, Daniels T, Allred B, Uejo A, Kosiorek H, Bruso M, Keole S. Advantages of intensity modulated proton therapy during hippocampal avoidance whole brain radiation therapy. Phys Imaging Radiat Oncol. 2018 Oct; 8:28-32 Epub 2018 Nov 27
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  156. Graffeo CS, Link MJ, Brown PD, Young WF Jr, Pollock BE. Hypopituitarism After Single-Fraction Pituitary Adenoma Radiosurgery: Dosimetric Analysis Based on Patients Treated Using Contemporary Techniques. Int J Radiat Oncol Biol Phys. 2018 Jul 1; 101 (3):618-623 Epub 2018 Mar 08
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  157. Blumenthal DT, Won M, Mehta MP, Gilbert MR, Brown PD, Bokstein F, Brachman DG, Werner-Wasik M, Hunter GK, Valeinis E, Hopkins K, Souhami L, Howard SP, Lieberman FS, Shrieve DC, Wendland MM, Robinson CG, Zhang P, Corn BW. Short delay in initiation of radiotherapy for patients with glioblastoma-effect of concurrent chemotherapy: a secondary analysis from the NRG Oncology/Radiation Therapy Oncology Group database. Neuro Oncol. 2018 Jun 18; 20 (7):966-974
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  158. Zhang Z, Yang J, Ho A, Jiang W, Logan J, Wang X, Brown PD, McGovern SL, Guha-Thakurta N, Ferguson SD, Fave X, Zhang L, Mackin D, Court LE, Li J. A predictive model for distinguishing radiation necrosis from tumour progression after gamma knife radiosurgery based on radiomic features from MR images. Eur Radiol. 2018 Jun; 28 (6):2255-2263 Epub 2017 Nov 24
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  296. Johnson DR, Brown PD, Galanis E, Hammack JE. Pilocytic astrocytoma survival in adults: analysis of the Surveillance, Epidemiology, and End Results Program of the National Cancer Institute. J Neurooncol. 2012 May; 108 (1):187-93 Epub 2012 Feb 25
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  297. Wang XS, Rhines LD, Shiu AS, Yang JN, Selek U, Gning I, Liu P, Allen PK, Azeem SS, Brown PD, Sharp HJ, Weksberg DC, Cleeland CS, Chang EL. Stereotactic body radiation therapy for management of spinal metastases in patients without spinal cord compression: a phase 1-2 trial. Lancet Oncol. 2012 Apr; 13: (4)395-402.
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  299. Ahmed KA, Stauder MC, Miller RC, Bauer HJ, Rose PS, Olivier KR, Brown PD, Brinkmann DH, Laack NN. Stereotactic body radiation therapy in spinal metastases. Int J Radiat Oncol Biol Phys. 2012 Apr 1; 82 (5):e803-9 Epub 2012 Feb 11
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  301. Laack NN, O'Neill BP, Ballman KV, O'Fallon JR, Carrero XW, Kurtin PJ, Scheithauer BW, Brown PD, Habermann TM, Colgan JP, Gilbert MR, Hawkins RB, Morton RF, Windschitl HE, Fitch TR, Pajon ER Jr, North Central Cancer Treatment Group and Mayo Clinic. CHOD/BVAM chemotherapy and whole-brain radiotherapy for newly diagnosed primary central nervous system lymphoma. Int J Radiat Oncol Biol Phys. 2011 Oct 1; 81 (2):476-82 Epub 2010 Aug 26
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  302. Sarkaria JN, Galanis E, Wu W, Peller PJ, Giannini C, Brown PD, Uhm JH, McGraw S, Jaeckle KA, Buckner JC. North Central Cancer Treatment Group Phase I trial N057K of everolimus (RAD001) and temozolomide in combination with radiation therapy in patients with newly diagnosed glioblastoma multiforme. Int J Radiat Oncol Biol Phys. 2011 Oct 1; 81 (2):468-75 Epub 2010 Sept 23
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  304. Caudill JS, Brown PD, Cerhan JH, Rummans TA. Selective serotonin reuptake inhibitors, glioblastoma multiforme, and impact on toxicities and overall survival: the mayo clinic experience. Am J Clin Oncol. 2011 Aug; 34 (4):385-7
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  306. Stauder MC, Macdonald OK, Olivier KR, Call JA, Lafata K, Mayo CS, Miller RC, Brown PD, Bauer HJ, Garces YI. Early pulmonary toxicity following lung stereotactic body radiation therapy delivered in consecutive daily fractions. Radiother Oncol. 2011 May; 99 (2):166-71 Epub 2011 May 14
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  344. Leenstra JL, Rodriguez FJ, Frechette CM, Giannini C, Stafford SL, Pollock BE, Schild SE, Scheithauer BW, Jenkins RB, Buckner JC, Brown PD. Central neurocytoma: management recommendations based on a 35-year experience. Int J Radiat Oncol Biol Phys. 2007 Mar 15; 67 (4):1145-54 Epub 2006 Dec 21
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  366. McWilliams RR, Rao RD, Brown PD, Link MJ, Buckner JC. Treatment options for brain metastases from melanoma. Expert Review of Anticancer Therapy. 2005 Oct; 5(5):809-20.
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  372. Pollock BE, Foote RL, Link MJ, Stafford SL, Brown PD, Schomberg PJ. Repeat radiosurgery for idiopathic trigeminal neuralgia. Int J Radiat Oncol Biol Phys. 2005 Jan 1; 61 (1):192-5
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  373. Olivier KR, Brown PD, Stafford SL, Ansell SM, Martenson JA. Efficacy and treatment-related toxicity of radiotherapy for early-stage primary non-Hodgkin lymphoma of the parotid gland. Int J Radiat Oncol Biol Phys. 2004 Dec 1; 60(5):1510-4.
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  374. Prisciandaro JI, Frechette CM, Herman MG, Brown PD, Garces YI, Foote RL. A methodology to determine margins by EPID measurements of patient setup variation and motion as applied to immobilization devices. Med Phys. 2004 Nov; 31 (11):2978-88
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  375. Laack NN, Brown PD. Cognitive sequelae of brain radiation in adults. Semin Oncol. 2004 Oct; 31 (5):702-13
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  376. Krishnan S, Brown PD, Scheithauer BW, Ebersold MJ, Hammack JE, Buckner JC. Choroid plexus papillomas: a single institutional experience. J Neurooncol. 2004 May; 68 (1):49-55
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  379. Pollock BE, Gorman DA, Brown PD. Radiosurgery for arteriovenous malformations of the basal ganglia, thalamus, and brainstem. J Neurosurg. 2004 Feb; 100(2):210-4.
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  380. Pollock BE, Link MJ, Foote RL, Stafford SL, Brown PD, Schomberg PJ. Radiosurgery as primary management for meningiomas extending into the internal auditory canal. Stereotactic & Functional Neurosurgery. 2004; 82(2-3):98-103.
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  381. Brown PD, Kline RW, Petersen IA, Haddock MG. Irradiation of the inguinal lymph nodes in patients of differing body habitus: A comparison of techniques and resulting normal tissue complication probabilities. Med Dosim. 2004; 29(3):217-22.
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  382. McWilliams RR, Brown PD, Buckner JC, Link MJ, Markovic SN. Treatment of brain metastases from melanoma. Mayo Clin Proc. 2003 Dec; 78(12):1529-36.
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  383. Brown PD, Wald JT, McDermott MW, Baumann GS, Cloughesy TF, Oncodiagosis panel, 2002 RSNA Scientific Assembly. Oncodiagnosis panel: 2002. Metastatic NSCLC. Radiographics. 2003 Nov-Dec; 23 (6):1591-611
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  384. Brown PD, Wald JT, McDermott MW, Baumann GS, Cloughesy TF, Oncodiagosis panel, 2002 RSNA Scientific Assembly. Oncodiagnosis panel: 2002. Patient's symptoms not related to the lesion seen in the MR images. Radiographics. 2003 Nov-Dec; 23 (6):1591-611
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  385. Brown PD, Wald JT, McDermott MW, Baumann GS, Cloughesy TF, Oncodiagosis panel, 2002 RSNA Scientific Assembly. Oncodiagnosis panel: 2002. Primary glial neoplasm or less likely an intracranial abscess. Radiographics. 2003 Nov-Dec; 23 (6):1591-611
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  386. Foote RL, Brown PD, Garces YI, McIver B, Kasperbauer JL. Is there a role for radiation therapy in the management of Hurthle cell carcinoma? Int J Radiat Oncol Biol Phys. 2003 Jul 15; 56 (4):1067-72
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  387. Brown PD, Buckner JC, Uhm JH, Shaw EG. The neurocognitive effects of radiation in adult low-grade glioma patients. Neuro Oncol. 2003 Jul; 5 (3):161-7
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  388. Brown PD, Buckner JC, O'Fallon JR, Iturria NL, Brown CA, O'Neill BP, Scheithauer BW, Dinapoli RP, Arusell RM, Curran WJ, Abrams R, Shaw EG. Effects of radiotherapy on cognitive function in patients with low-grade glioma measured by the folstein mini-mental state examination. J Clin Oncol. 2003 Jul 1; 21 (13):2519-24
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  389. Stafford SL, Pollock BE, Leavitt JA, Foote RL, Brown PD, Link MJ, Gorman DA, Schomberg PJ. A study on the radiation tolerance of the optic nerves and chiasm after stereotactic radiosurgery. Int J Radiat Oncol Biol Phys. 2003 Apr 1; 55 (5):1177-81
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  390. Bartleson JD, Krecke KN, O'Neill BP, Brown PD. Reversible, strokelike migraine attacks in patients with previous radiation therapy. Neuro Oncol. 2003 Apr; 5 (2):121-7
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  391. Buckner JC, Gesme D Jr, O'Fallon JR, Hammack JE, Stafford S, Brown PD, Hawkins R, Scheithauer BW, Erickson BJ, Levitt R, Shaw EG, Jenkins R. Phase II trial of procarbazine, lomustine, and vincristine as initial therapy for patients with low-grade oligodendroglioma or oligoastrocytoma: efficacy and associations with chromosomal abnormalities. J Clin Oncol. 2003 Jan 15; 21 (2):251-5
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  392. Pollock BE, Brown PD, Foote RL, Stafford SL, Schomberg PJ. Properly selected patients with multiple brain metastases may benefit from aggressive treatment of their intracranial disease. J Neurooncol. 2003 Jan; 61 (1):73-80
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  393. Sarkar A, Pollock BE, Brown PD, Gorman DA. Evaluation of gamma knife radiosurgery in the treatment of oligodendrogliomas and mixed oligodendroastrocytomas. J Neurosurg. 2002 Dec; 97 (5 Suppl):653-6
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  394. Brown PD, Brown CA, Pollock BE, Gorman DA, Foote RL. Stereotactic radiosurgery for patients with "radioresistant" brain metastases. Neurosurgery. 2002 Sep; 51 (3):656-65; discussion 665-7
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  395. Brown PD, Bonner JA, Foote RL, Frytak S, Marks RS, Richardson RL, Creagan ET. Long-term results of a phase I/II study of high-dose thoracic radiotherapy with concomitant cisplatin and etoposide in limited stage small-cell lung cancer. Am J Clin Oncol. 2001 Dec; 24 (6):556-61
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  396. Brown PD, Eshleman JS, Foote RL, Strome SE. An analysis of facial nerve function in irradiated and unirradiated facial nerve grafts. Int J Radiat Oncol Biol Phys. 2000 Oct 1; 48 (3):737-43
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  397. Brown PD, Stafford SL, Schild SE, Martenson JA, Schiff D. Metastatic spinal cord compression in patients with colorectal cancer. J Neurooncol. 1999 Sep; 44 (2):175-80
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  398. Schild SE, Stafford SL, Brown PD, Wood CP, Scheithauer BW, Schomberg PJ, Wong WW, Lyons MK, Shaw EG. The results of radiotherapy for brainstem tumors. J Neurooncol. 1998 Nov; 40 (2):171-7
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