Precautions

Drug information provided by: Merative, Micromedex®

If you will be using this medicine for a long time, it is important that your doctor check the progress of you or your child at regular visits. This will allow your doctor to see if the medicine is working properly and to decide whether you should continue to use it. Blood tests may be needed to check for unwanted effects.

Tell your doctor if you or anyone in your home has ever had a positive reaction to a tuberculosis skin test.

Your body's ability to fight infection may be reduced while you are being treated with anakinra, it is very important that you call your doctor at the first signs of any infection (for example, if you get a fever or chills).

Do not use this medicine together with adalimumab (Humira®), certolizumab pegol (Cimzia®), etanercept (Enbrel®), golimumab (Simponi®), or infliximab (Remicade®).

Anakinra may cause serious allergic reactions, including anaphylaxis or angioedema, which can be life-threatening and requires immediate medical attention. Check with your doctor right away if you or your child have a rash, itching, large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs, trouble breathing, or chest pain after you receive the medicine.

This medicine may increase your risk of developing infections. Tell your doctor if you have any kind of infection before you start using this medicine. Also tell your doctor if you have ever had an infection that would not go away or an infection that kept coming back.

Do not have any live vaccines (immunizations) while you or your child are being treated with anakinra. Be sure to ask your child's doctor if you have any questions about this.

This medicine lowers the number of some types of blood cells in your body. Because of this, you may get infections more easily. To help with these problems, avoid being near people who are sick or have infections. Wash your hands often.

This medicine may cause severe tenderness and pain at the site of the injection. Call your doctor right away if you have bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site.

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Portions of this document last updated: April 01, 2024

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