Before Using
Drug information provided by: Merative, Micromedex®
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of penbutolol in the pediatric population. Safety and efficacy have not been established.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of penbutolol in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving penbutolol.
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Drug Interactions
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
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Albuterol
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Ceritinib
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Clonidine
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Crizotinib
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Darunavir
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Diltiazem
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Dronedarone
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Epinephrine
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Fenoldopam
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Fexinidazole
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Fingolimod
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Formoterol
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Indacaterol
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Iobenguane I 131
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Iohexol
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Lacosamide
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Levalbuterol
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Olodaterol
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Oxymetazoline
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Ponesimod
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Rivastigmine
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Salmeterol
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Siponimod
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Terbutaline
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Verapamil
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Vilanterol
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
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Acarbose
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Aceclofenac
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Acemetacin
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Acetyldigoxin
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Albiglutide
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Alfuzosin
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Alogliptin
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Amtolmetin Guacil
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Aspirin
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Bromfenac
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Bufexamac
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Bunazosin
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Canagliflozin
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Celecoxib
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Chlorpropamide
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Choline Salicylate
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Clonixin
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Dapagliflozin
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Deslanoside
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Dexibuprofen
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Dexketoprofen
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Diclofenac
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Diflunisal
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Digitoxin
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Digoxin
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Dipyrone
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Doxazosin
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Droxicam
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Dulaglutide
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Empagliflozin
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Ertugliflozin
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Etodolac
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Etofenamate
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Etoricoxib
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Exenatide
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Felbinac
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Fenoprofen
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Fepradinol
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Feprazone
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Floctafenine
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Flufenamic Acid
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Flurbiprofen
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Glimepiride
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Glipizide
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Glyburide
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Ibuprofen
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Indomethacin
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Insulin Aspart, Recombinant
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Insulin Degludec
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Insulin Detemir
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Insulin Glargine, Recombinant
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Insulin Glulisine
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Insulin Human Inhaled
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Insulin Human Isophane (NPH)
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Insulin Human Regular
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Insulin Lispro, Recombinant
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Ketoprofen
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Ketorolac
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Lidocaine
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Linagliptin
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Liraglutide
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Lixisenatide
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Lornoxicam
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Loxoprofen
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Lumiracoxib
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Meclofenamate
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Mefenamic Acid
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Meloxicam
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Metformin
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Metildigoxin
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Miglitol
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Morniflumate
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Moxisylyte
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Nabumetone
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Naproxen
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Nateglinide
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Nepafenac
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Niflumic Acid
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Nimesulide
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Nimesulide Beta Cyclodextrin
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Oxaprozin
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Oxyphenbutazone
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Parecoxib
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Phenoxybenzamine
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Phentolamine
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Phenylbutazone
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Piketoprofen
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Pioglitazone
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Piroxicam
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Pramlintide
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Pranoprofen
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Prazosin
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Proglumetacin
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Propyphenazone
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Proquazone
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Repaglinide
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Rofecoxib
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Rosiglitazone
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Salicylic Acid
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Salsalate
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Saxagliptin
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Sitagliptin
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Sodium Salicylate
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St John's Wort
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Sulindac
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Tamsulosin
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Tenoxicam
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Terazosin
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Tiaprofenic Acid
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Tolazamide
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Tolbutamide
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Tolfenamic Acid
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Tolmetin
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Trimazosin
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Urapidil
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Valdecoxib
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Vildagliptin
Other Interactions
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
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Anaphylactic reaction (severe), history of—May increase risk for repeated anaphylactic reactions.
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Angina (severe chest pain) or
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Heart attack, recent or
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Heart failure, history of or
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Heart or blood vessel disease (e.g., coronary artery disease)—Use with caution. May make these conditions worse.
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Asthma or
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Bradycardia (slow heartbeat) or
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Cardiogenic shock (shock caused by heart attack) or
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Heart block—Should not be used in patients with these conditions.
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Diabetes or
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Hyperthyroidism (overactive thyroid) or
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Hypoglycemia (low blood sugar)—May cover up some of the signs and symptoms of these diseases, such as a fast heartbeat.
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Kidney disease—Use with caution. The effects may be increased because of slower removal from the body.
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Lung disease (e.g., bronchitis, emphysema)—Use with caution. May cause difficulty with breathing in patients with this condition.
Portions of this document last updated: Aug. 01, 2024
Copyright: © Merative US L.P. 1973, 2024. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.