Before Using
Drug information provided by: Merative, Micromedex®
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of labetalol in the pediatric population. Safety and efficacy have not been established.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of labetalol in the elderly.
Breastfeeding
Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.
Drug Interactions
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
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Albuterol
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Carbamazepine
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Ceritinib
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Clonidine
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Crizotinib
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Darunavir
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Diltiazem
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Dronedarone
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Fenoldopam
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Fexinidazole
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Fingolimod
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Formoterol
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Halothane
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Indacaterol
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Iobenguane I 123
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Iobenguane I 131
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Iohexol
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Lacosamide
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Levalbuterol
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Levoketoconazole
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Lonafarnib
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Mavacamten
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Methotrexate
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Olodaterol
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Oxymetazoline
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Ponesimod
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Rivastigmine
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Salmeterol
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Siponimod
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Terbutaline
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Verapamil
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Vilanterol
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
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Acarbose
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Aceclofenac
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Acemetacin
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Acetyldigoxin
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Albiglutide
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Alfuzosin
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Alogliptin
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Amtolmetin Guacil
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Aspirin
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Bromfenac
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Bufexamac
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Bunazosin
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Canagliflozin
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Celecoxib
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Chlorpropamide
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Choline Salicylate
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Cimetidine
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Clonixin
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Dapagliflozin
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Deslanoside
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Dexibuprofen
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Dexketoprofen
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Diclofenac
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Diflunisal
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Digitoxin
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Digoxin
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Dipyrone
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Doxazosin
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Droxicam
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Dulaglutide
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Empagliflozin
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Enflurane
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Epinephrine
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Ertugliflozin
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Etodolac
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Etofenamate
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Etoricoxib
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Exenatide
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Felbinac
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Fenoprofen
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Fepradinol
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Feprazone
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Floctafenine
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Flufenamic Acid
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Flurbiprofen
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Glimepiride
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Glipizide
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Glyburide
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Ibuprofen
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Indomethacin
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Insulin Aspart, Recombinant
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Insulin Degludec
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Insulin Detemir
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Insulin Glargine, Recombinant
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Insulin Glulisine
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Insulin Human Inhaled
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Insulin Human Isophane (NPH)
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Insulin Human Regular
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Insulin Lispro, Recombinant
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Isoflurane
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Ketoprofen
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Ketorolac
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Linagliptin
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Liraglutide
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Lixisenatide
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Lornoxicam
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Loxoprofen
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Lumiracoxib
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Magnesium Sulfate
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Meclofenamate
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Mefenamic Acid
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Meloxicam
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Metformin
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Metildigoxin
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Miglitol
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Morniflumate
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Moxisylyte
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Nabumetone
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Naproxen
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Nateglinide
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Nepafenac
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Niflumic Acid
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Nimesulide
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Nimesulide Beta Cyclodextrin
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Oxaprozin
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Oxyphenbutazone
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Parecoxib
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Phenoxybenzamine
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Phentolamine
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Phenylbutazone
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Piketoprofen
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Pioglitazone
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Piroxicam
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Pramlintide
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Pranoprofen
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Prazosin
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Proglumetacin
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Propyphenazone
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Proquazone
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Repaglinide
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Rofecoxib
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Rosiglitazone
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Salicylic Acid
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Salsalate
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Saxagliptin
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Sitagliptin
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Sodium Salicylate
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St John's Wort
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Sulindac
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Tamsulosin
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Tenoxicam
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Terazosin
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Tiaprofenic Acid
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Tolazamide
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Tolbutamide
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Tolfenamic Acid
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Tolmetin
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Trimazosin
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Urapidil
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Valdecoxib
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Vildagliptin
Other Interactions
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
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Angina (severe chest pain)—May provoke chest pain if stopped too quickly.
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Asthma or
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Bradycardia, severe (slow heartbeat) or
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Cardiogenic shock (shock caused by heart attack) or
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Obstructive airway disease, or
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Heart block or
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Heart failure or
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Hypotension (low blood pressure), severe and prolonged—Should not be used in patients with these conditions.
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Diabetes or
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Hyperthyroidism (overactive thyroid) or
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Hypoglycemia (low blood sugar)—May cover up some of the signs and symptoms of these diseases, such as a fast heartbeat.
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Hypotension (low blood pressure) or
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Ischemic heart disease or
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Lung disease or
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Pheochromocytoma (adrenal gland tumor)—Use with caution. May make these conditions worse.
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Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.
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Patients who are fasting (eg, surgery, not eating regularly, vomiting)—May increase risk of hypoglycemia (low blood sugar).
Portions of this document last updated: Aug. 01, 2024
Copyright: © Merative US L.P. 1973, 2024. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.