Precautions

Drug information provided by: Merative, Micromedex®

It is very important that your doctor check your progress closely while you are receiving this medicine. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to receive it. Blood tests may be needed to check for unwanted effects.

This medicine may cause bleeding problems. Check with your doctor right away if you have bleeding gums, coughing up blood, difficulty breathing or swallowing, dizziness, headache, increased menstrual flow or vaginal bleeding, nosebleeds, paralysis, red or dark brown urine, or red or black, tarry stools.

Check with your doctor right away if you have anxiety, chest pain or discomfort, confusion, constipation, cough, diarrhea, difficulty in speaking, dizziness or lightheadedness, double vision, fainting, fast heartbeat, headache, inability to move the arms, legs, or facial muscle, nausea, pain, redness, or swelling in the arm or leg, pain or discomfort in the arms, jaw, back, or neck, slow speech, stomach pain, usually after eating a meal, sudden trouble breathing, sweating, vomiting. These may be symptoms of blood clotting problems (eg, deep vein thrombosis, pulmonary embolism, myocardial infarction, stroke).

Check with your doctor right away if you have blue-green to black skin discoloration, pain, redness, or sloughing of the skin at the injection site. These maybe symptoms of serious skin or tissue damage (eg, skin necrosis, gangrene).

This medicine lowers the number of some types of blood cells in your body. Because of this, you may bleed more easily. Stay away from rough sports or other situations where you could be bruised, cut, or injured. Brush and floss your teeth gently. Be careful when using sharp objects, including razors and fingernail clippers.

This medicine may cause serious allergic reactions, including anaphylaxis, which can be life-threatening and require immediate medical attention. Tell your doctor right away if you have a cough, difficulty with swallowing, dizziness, a fast heartbeat, lightheadedness or fainting, trouble breathing, chest tightness, swelling in your face, hands, tongue, or throat after you receive the medicine.

Make sure any doctor or dentist who treats you knows that you are using this medicine before you have surgery.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription and nonprescription (over-the-counter [OTC]) medicines, and herbal or vitamin supplements.