Proper Use

Drug information provided by: Merative, Micromedex®

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

This medicine comes with a Medication Guide and patient instructions. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Take this medicine with food. Do not mix this medicine with water or other liquids.

To use the oral liquid:

  • Shake the bottle well for at least 30 seconds by continuously turning it up and down. Stop when the oral liquid is mixed well and looks the same throughout.
  • Open the bottle by pressing down on the cap and turn the cap to the left (counter-clockwise).
  • If you are using the medicine for the first time, take the provided oral syringe and firmly insert the tip of the oral syringe into the bottle adapter opening. If it is not the first time, take the oral syringe and push the plunger all the way down (to remove the air) and firmly insert the tip of the oral syringe into the bottle adapter opening.
  • Hold the syringe in place and turn the bottle upside down. Slowly pull the plunger down to pull out a small amount of the oral liquid. Then push the plunger all the way up to remove any air bubbles.
  • Slowly pull the plunger down until you reach the prescribed dose. While keeping the plunger in the same position, turn the bottle upright and place it on a flat surface. Remove the oral syringe by gently twisting or pulling it out from the bottle adapter opening. Do not hold the plunger because it may come out.
  • Place the tip of the oral syringe against the inside of the cheek and slowly push the plunger all the way down until there is no medicine left in the syringe.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (suspension):
    • For Duchenne muscular dystrophy (DMD):
      • Adults and children 6 years of age and older—Dose is based on body weight and must be determined by your doctor. Your doctor may adjust your dose as needed and tolerated.
        • Weighing 60 kilograms (kg) or more—53.2 milligrams (mg) or 6 milliliters (mL) 2 times a day.
        • Weighing 40 kg to less than 60 kg—44.3 mg or 5 mL 2 times a day.
        • Weighing 20 kg to less than 40 kg—31 mg or 3.5 mL 2 times a day.
        • Weighing 10 kg to less than 20 kg—22.2 mg or 2.5 mL 2 times a day.
      • Children younger than 6 years of age—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Throw away any unused liquid after 60 days of opening the bottle.

Portions of this document last updated: July 01, 2024

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