Precautions
Drug information provided by: Merative, Micromedex®
It is very important that your doctor check your progress at regular visits. This will allow your doctor to see if this medicine is working properly and to decide whether you should continue to use it. Blood tests are needed to check for unwanted effects.
Do not use this medicine together with fluconazole (Diflucan®).
Tell your doctor if you are pregnant or plan to become pregnant. If you can get pregnant, use an effective form of birth control to keep from getting pregnant. Tell your doctor right away if you think you have become pregnant during treatment.
You will need to have a skin test for tuberculosis before you start using this medicine. Tell your doctor if you or anyone in your home has ever had a positive reaction to a tuberculosis skin test.
Your body's ability to fight infections may be reduced while you are using this medicine. It is very important that you call your doctor at the first sign of an infection. Check with your doctor right away if you have a fever, chills, cough, flu-like symptoms, or unusual tiredness or weakness.
This medicine may increase your risk for cancer (eg, lymphoma, lung cancer, non-melanoma skin cancer). Tell your doctor right away if you have black, tarry stools, general feeling of illness, swollen glands, weight loss, yellow skin and eyes, persistent non-healing sore, reddish patch or irritated area, shiny bump, pink growth, or white, yellow or waxy scar-like area on the skin.
This medicine may increase your risk for serious heart or blood vessel problems (eg, heart attack, stroke), especially in patients with rheumatoid arthritis who are 50 years of age and older and with a heart or blood vessel disease. Call your doctor right away if you have chest pain or discomfort, confusion, difficulty in speaking, double vision, headache, inability to move arms, legs, or facial muscles, nausea, pain or discomfort in the arms, jaw, back, or neck, sweating, trouble breathing, or vomiting.
This medicine may increase your risk of developing blood clots (eg, cerebral venous sinus thrombosis, deep vein thrombosis, pulmonary embolism), especially in patients with rheumatoid arthritis who are 50 years of age and older and with a heart or blood vessel disease. Check with your doctor right away if you have anxiety, chest pain, confusion, cough, dizziness, lightheadedness, or fainting, fast heartbeat, numbness of the hands, pain, redness, or swelling in the arm or leg, or trouble breathing.
This medicine may cause stomach or bowel perforation (tear). Check with your doctor right away if you have bloody, black, or tarry stools, heartburn, indigestion, nausea, severe stomach pain, cramping, or burning, trouble breathing, or vomiting of material that looks like coffee grounds, severe and continuing.
This medicine lowers the number of some types of blood cells in your body. Because of this, you may bruise or get infections more easily. To help with these problems, avoid being near people who are sick or have infections. Wash your hands often. Stay away from rough sports or other situations where you could be bruised or injured.
While you are being treated with deuruxolitinib, and after you stop treatment with it, do not have any immunizations (vaccines) without your doctor's approval. Deuruxolitinib may lower your body's resistance and there is a chance you might get the infection the vaccine is meant to prevent. In addition, you should not be around other persons living in your household who receive live virus vaccines because there is a chance they could pass the virus on to you. Some examples of live vaccines include measles, mumps, influenza (nasal flu vaccine), poliovirus (oral form), rotavirus, and rubella. If you have questions about this, talk to your doctor.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
Portions of this document last updated: Sept. 01, 2024
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