Side Effects
Drug information provided by: Merative, Micromedex®
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common-Entacapone
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Twitching, twisting, or uncontrolled repetitive movements of the tongue, lips, face, arms, or legs
Incidence not known-Carbidopa and Levodopa and/or Levodopa alone
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Bleeding gums
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bloody or black, tarry stools
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bloody or cloudy urine
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change in size, shape, or color of an existing mole
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changes in skin color
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chest pain, discomfort, or tightness
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constipation
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constricted pupil
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convulsions
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cough
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difficult or labored breathing
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difficulty with speaking
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drooling
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drooping eyelid (ptosis)
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facial dryness
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fast, irregular, or pounding heartbeat
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fever with or without chills
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general feeling of illness
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hallucinations (seeing, hearing, or feeling things that are not there)
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hoarseness
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large, flat, blue, or purplish patches in the skin
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large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
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loss of appetite
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loss of bladder control
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lower abdominal or stomach pain
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lower back or side pain
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mole that leaks fluid or bleeds
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muscle cramps or spasms
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muscle pain or stiffness
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muscle trembling, jerking, or stiffness
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nausea
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pain
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painful or difficult urination
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pinpoint red spots on the skin
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raised red swellings on the skin, the buttocks, legs, or ankles
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restlessness
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severe mental changes
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shakiness and unsteady walk
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shuffling walk
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sore throat
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sores, ulcers, or white spots on the lips or in the mouth
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sweating
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swollen glands
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trembling, or other problems with muscle control or coordination
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unusual bleeding or bruising
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unusual tiredness or weakness
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vomiting
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common-Entacapone
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Absence of or decrease in body movement
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diarrhea
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dizziness
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urine discoloration
Less common-Entacapone
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Acid or sour stomach
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anxiety
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belching
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bitter, sour, or unusual taste in the mouth
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bloated
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burning feeling in the chest or stomach
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dry mouth
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excess air or gas in the stomach or intestines
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fear
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full feeling
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heartburn
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hyperventilation
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increased sweating
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indigestion
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irritability
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lack or loss of strength
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passing gas
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restlessness
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sleepiness or unusual drowsiness
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stomach discomfort or upset
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swollen mouth and tongue
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tenderness in the stomach area
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trouble sleeping
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urge to have bowel movement
Incidence not known-Carbidopa and Levodopa and/or Levodopa alone
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Being forgetful
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bladder pain
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blurred vision
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body aches or pain
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burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
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burning and upper abdominal or stomach pain
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burning sensation of the tongue
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clenching, gnashing, or grinding teeth
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confusion about identity, place, and time
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dark saliva
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dark sweat
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decreased mental acuity
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difficulty swallowing
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discouragement
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double vision
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ear congestion
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enlarged pupils
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excessive watering of the mouth
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fainting
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false or unusual sense of well-being
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feeling like you will pass out
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feeling of warmth
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feeling sad or empty
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flushing
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hair loss
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headache
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hiccups
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hives or welts
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increased blinking
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increased interest in sexual ability, desire, drive, or performance
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increased interest in sexual intercourse
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lack of appetite
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large, hard skin blisters
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leg pain
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loss of voice
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muscle spasm, especially of the neck and back
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nasal congestion
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nightmares
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numbness
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pain in the chest below the breastbone
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painful or prolonged erection of the penis
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pharyngeal pain
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pounding in the ears
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problems with memory or speech
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redness of the face, neck, arms, and occasionally upper chest
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runny nose
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sense of stimulation
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skin rash
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sleeplessness
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slow movement
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slow or fast heartbeat
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slow reflexes
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sneezing
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swelling
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tremor, increased
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trouble concentrating
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trouble recognizing objects
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trouble thinking and planning
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urinary frequency
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urinary retention
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weight gain
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weight loss
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Portions of this document last updated: Sept. 01, 2024
Copyright: © Merative US L.P. 1973, 2024. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.