钙补充剂：心脏病发作的风险因素？

我听说钙补充剂可能增加心脏病发作的风险。请问是这样吗？

回答 Rekha Mankad, M.D.

一些证据表明，钙补充剂可能会增加出现心脏病发作的风险。钙补充剂通常用于治疗或预防骨病，例如骨质疏松症。

一项研究综述发现，钙补充剂会增加患心脏病的风险，尤其是在健康的绝经后女性中。但其他研究表明，钙补充剂不会增加该风险。

需要开展进一步研究，以了解钙补充剂对心脏病发作整体风险的影响。已知来源于食物（例如奶制品和绿叶蔬菜）的钙不会引起问题。

服用钙（联合维生素 D）确实对钙缺失者或骨量丢失者有益。请咨询医生您是否适合服用钙补充剂。

With

Rekha Mankad, M.D.

Heravi AS, et al. Vitamin D and calcium supplements: Helpful, harmful or neutral for cardiovascular risk? Methodist Debakey Cardiovascular Journal. 2019; doi: 10.14797/mdcj-15-3-207.
Myung SK, et al. Calcium supplements and risk of cardiovascular disease: A meta-analysis of clinical trials. Nutrients. 2021; doi:10.3390/nu13020368.
Yang C, et al. The evidence and controversy between dietary calcium intake and calcium supplementation and the risk of cardiovascular disease: A systematic review and meta-analysis of cohort studies and randomized controlled trials. Journal of the American College of Nutrition. 2019; doi: 10.1080/07315724.2019.1649219.
Morelli MB, et al. Calcium supplements: Good for the bone, bad for the heart? A systematic updated appraisal. Atherosclerosis. 2020; doi: 10.1016/j.atherosclerosis.2019.12.003.
Mankad R (expert opinion). Mayo Clinic. March 8, 2021.

March 23, 2023