搜索医生

Thomas G. Osborn, M.D.

  1. Internist
  2. Rheumatologist
预约门诊

出版物

  1. Nln I, Shum J, Ghodke-Puranik Y, Tipon R, Triese D, Amin S, Makol A, Osborn T, Chowdhary V, Thanarajasingam U, Wampler Muskardin TL, Muskardin TLW, Oke V, Gunnarsson I, Zickert A, Zervou MI, Boumpas DT, Svenungsson E, Goulielmos GN, Niewold TB. Regional European genetic ancestry predicts type I interferon level and risk of severe viral infection. QJM. 2024 Aug 1; 117 (8):581-588
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  2. Cull DB, Angeli AM, Osborn TG. 18-Year-Old Woman With Dizziness, Weakness, and Weight Loss. Mayo Clin Proc. 2024 Aug; 99 (8):1306-1311 Epub 2024 June 22
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  3. Coffey CM, Sandhu AS, Crowson CS, Asante D, Matteson EL, Osborn TG, Warrington KJ, Makol A. Outpatient healthcare utilization among incident cases of systemic sclerosis: results from a population-based US cohort (1988-2016). Scand J Rheumatol. 2022 Jul; 51 (4):323-328 Epub 2021 July 07
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  4. Iwamoto T, Dorschner JM, Selvaraj S, Mezzano V, Jensen MA, Vsetecka D, Amin S, Makol A, Osborn T, Moder K, Chowdhary VR, Izmirly P, Belmont HM, Clancy RM, Buyon JP, Wu M, Loomis CA, Niewold TB. High Systemic Type I Interferon Activity Is Associated With Active Class III/IV Lupus Nephritis. J Rheumatol. 2022 Apr; 49 (4):388-397 Epub 2021 Nov 15
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  5. Ghodke-Puranik Y, Jin Z, Zimmerman KD, Ainsworth HC, Fan W, Jensen MA, Dorschner JM, Vsetecka DM, Amin S, Makol A, Ernste F, Osborn T, Moder K, Chowdhary V, Langefeld CD, Niewold TB. Single-cell expression quantitative trait loci (eQTL) analysis of SLE-risk loci in lupus patient monocytes. Arthritis Res Ther. 2021 Nov 30; 23 (1):290
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  6. Radwan YA, Kurmann RD, Sandhu AS, El-Am EA, Crowson CS, Matteson EL, Osborn TG, Warrington KJ, Mankad R, Makol A. Systemic Sclerosis Portends Increased Risk of Conduction and Rhythm Abnormalities at Diagnosis and During Disease Course: A US Population-Based Cohort. J Scleroderma Relat Disord. 2021 Oct; 6 (3):277-285 Epub 2021 July 28
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  7. Coffey CM, Sandhu AS, Crowson CS, Achenbach SJ, Matteson EL, Osborn TG, Warrington KJ, Makol A. Hospitalization Rates Are Highest in the First 5 Years of Systemic Sclerosis: Results From a Population-based Cohort (1980-2016). J Rheumatol. 2021 Jun; 48 (6):877-882 Epub 2020 Nov 15
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  8. Zhou B, Bartholmai BJ, Kalra S, Osborn T, Zhang X. Lung mass density prediction using machine learning based on ultrasound surface wave elastography and pulmonary function testing. J Acoust Soc Am. 2021 Feb; 149 (2):1318
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  9. Breen TJ, Osborn TG, Kleinman Sween J. Untreated Takayasu arteritis: an unusual case of widespread disease. BMJ Case Rep. 2020 Aug 24; 13 (8)
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  10. Kurmann RD, Sandhu AS, Crowson CS, Matteson EL, Osborn TG, Warrington KJ, Mankad R, Makol A. Cardiovascular Risk Factors and Atherosclerotic Cardiovascular Events Among Incident Cases of Systemic Sclerosis: Results From a Population-Based Cohort (1980-2016). Mayo Clin Proc. 2020 Jul; 95 (7):1369-1378
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  11. Zhang X, Zhou B, Osborn T. Ultrasound Surface Wave Elastography for Assessing Scleroderma. Ultrasound Med Biol. 2020 May; 46 (5):1263-1269 Epub 2020 Feb 25
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  12. Thanarajasingam U, Muppirala AN, Jensen MA, Ghodke-Puranik Y, Dorschner JM, Vsetecka DM, Amin S, Makol A, Ernste F, Osborn T, Moder K, Chowdhary V, Niewold TB. Type I Interferon Predicts an Alternate Immune System Phenotype in Systemic Lupus Erythematosus. ACR Open Rheumatol. 2019 Oct; 1 (8):499-506 Epub 2019 Aug 19
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  13. Clay R, Bartholmai BJ, Zhou B, Karwoski R, Peikert T, Osborn T, Rajagopalan S, Kalra S, Zhang X. Assessment of Interstitial Lung Disease Using Lung Ultrasound Surface Wave Elastography: A Novel Technique With Clinicoradiologic Correlates. J Thorac Imaging. 2019 Sep; 34 (5):313-319
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  14. Zhou B, Bartholmai BJ, Kalra S, Osborn TG, Zhang X. Lung US Surface Wave Elastography in Interstitial Lung Disease Staging. Radiology. 2019 May; 291 (2):479-484 Epub 2019 Mar 05
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  15. Zhang X, Zhou B, Osborn T, Bartholmai B, Kalra S. Lung Ultrasound Surface Wave Elastography for Assessing Interstitial Lung Disease. IEEE Trans Biomed Eng. 2019 May; 66 (5):1346-1352 Epub 2018 Oct 01
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  16. Zhang X, Zhou B, Bartholmai B, Kalra S, Osborn T. A quantitative method for measuring the changes of lung surface wave speed for assessing disease progression of interstitial lung disease. Ultrasound Med Biol. 2019 Mar; 45 (3):741-748 Epub 2018 Dec 29
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  17. Zhang X, Zhou B, Kalra S, Bartholmai B, Greenleaf J, Osborn T. An Ultrasound Surface Wave Technique for Assessing Skin and Lung Diseases. Ultrasound Med Biol. 2018 Feb; 44 (2):321-331 Epub 2017 Dec 01
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  18. Ghodke-Puranik Y, Dorschner JM, Vsetecka DM, Amin S, Makol A, Ernste F, Osborn T, Moder K, Chowdhary V, Eliopoulos E, Zervou MI, Goulielmos GN, Jensen MA, Niewold TB. Lupus-Associated Functional Polymorphism in PNP Causes Cell Cycle Abnormalities and Interferon Pathway Activation in Human Immune Cells. Arthritis Rheumatol. 2017 Dec; 69 (12):2328-2337 Epub 2017 Nov 09
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  19. Zhang X, Osborn T, Zhou B, Meixner D, Kinnick RR, Bartholmai B, Greenleaf JF, Kalra S. Lung Ultrasound Surface Wave Elastography: A Pilot Clinical Study. IEEE Trans Ultrason Ferroelectr Freq Control. 2017 Sep; 64 (9):1298-1304
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  20. Ungprasert P, Sagar V, Crowson CS, Amin S, Makol A, Ernste FC, Osborn TG, Moder KG, Niewold TB, Maradit-Kremers H, Ramsey-Goldman R, Chowdhary VR. Incidence of systemic lupus erythematosus in a population-based cohort using revised 1997 American College of Rheumatology and the 2012 Systemic Lupus International Collaborating Clinics classification criteria. Lupus. 2017 Mar; 26 (3):240-247 Epub 2016 July 11
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  21. Sunjaya DB, Koster MJ, Osborn TG. 61-Year-Old Woman With Systemic Lupus Erythematosus and Chest Pain. Mayo Clin Proc. 2017 Jan; 92: (1)153-158.
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  22. Jin Z, Fan W, Jensen MA, Dorschner JM, Bonadurer GF 3rd, Vsetecka DM, Amin S, Makol A, Ernste F, Osborn T, Moder K, Chowdhary V, Niewold TB. Single-cell gene expression patterns in lupus monocytes independently indicate disease activity, interferon and therapy. Lupus Sci Med. 2017; 4 (1):e000202 Epub 2017 June 25
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  23. Baqir M, Makol A, Osborn TG, Bartholmai BJ, Ryu JH. Mycophenolate mofetil for scleroderma-related interstitial lung disease: A real world experience. PLoS One. 2017; 12 (5):e0177107 Epub 2017 May 25
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  24. Zhang X, Osborn T, Kalra S. A noninvasive ultrasound elastography technique for measuring surface waves on the lung. Ultrasonics. 2016 Sep; 71:183-188 Epub 2016 June 27
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  25. Zhang X, Meixner D, Kinnick R, Osborn T, Barthalmai B, Greenleaf J, Kalra S. Lung ultrasound surface wave elastography IEEE International Ultrasonics Symposium, IUS. 2016; 2016-November:7728512.
  26. Abdellatief A, Balasubramaniam SC, Grube TJ, Gonzalez Santiago TM, Osborn TG, Pulido JS. Indocyanine green angiographic evidence of choroiditis in scleroderma. Retin Cases Brief Rep. 2015 Summer; 9: (3)231-4.
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  27. Bauer PR, Kalra S, Osborn TG, St Sauver J, Hanson AC, Schroeder DR, Ryu JH. Influence of autoimmune biomarkers on interstitial lung diseases: A tertiary referral center based case-control study. Respir Med. 2015 Mar; 109 (3):397-405 Epub 2015 Jan 31
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  28. Bauer PR, Schiavo DN, Osborn TG, Levin DL, St Sauver J, Hanson AC, Schroeder DR, Ryu JH. Influence of interstitial lung disease on outcome in systemic sclerosis: a population-based historical cohort study. Chest. 2013 Aug; 144 (2):571-577
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  29. Wilson ME, Wan SH, Beyder A, Osborn TG, Beckman TJ. Acute polyarticular gout presenting as delirium. J Clin Rheumatol. 2013 Jun; 19(4):221-2.
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  30. Higgins JV, Thanarajasingam U, Osborn TG. A unique case of relapsing polychondritis presenting with acute pericarditis. Case Rep Rheumatol. 2013; 2013:287592 Epub 2013 Dec 17
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  31. Patel AB, Hallemeier CL, Petersen IA, Jensen AW, Osborn TG, Miller RC. Acute and late toxicities of radiotherapy for patients with discoid lupus erythematosus: a retrospective case-control study. Radiat Oncol. 2012 Feb 16; 7:22
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  32. Manek NJ, Holmgren AR, Sandroni P, Osborn TG, Davis MD. Primary Raynaud phenomenon and small-fiber neuropathy: is there a connection? A pilot neurophysiologic study. Rheumatol Int. 2011 May; 31 (5):577-85 Epub 2009 Dec 25
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  33. Veetil BM, Osborn TG, Mayer DF. Extreme hypercomplementemia in the setting of mixed cryoglobulinemia. Clin Rheumatol. 2011 Mar; 30 (3):415-8 Epub 2011 Jan 07
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  34. Zhang X, Osborn TG, Pittelkow MR, Qiang B, Kinnick RR, Greenleaf JF. Quantitative assessment of scleroderma by surface wave technique. Med Eng Phys. 2011 Jan; 33: (1)31-7.
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  35. Maripuri S, Grande JP, Osborn TG, Fervenza FC, Matteson EL, Donadio JV, Hogan MC. Renal involvement in primary Sjogren's syndrome: a clinicopathologic study. Clin J Am Soc Nephrol. 2009 Sep; 4 (9):1423-31 Epub 2009 Aug 13
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  36. Kermani TA, Pislaru SV, Osborn TG. Acrocyanosis from phenazopyridine-induced sulfhemoglobinemia mistaken for Raynaud phenomenon. J Clin Rheumatol. 2009 Apr; 15(3):127-9.
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  37. Pinn ME, Gold DG, Petersen IA, Osborn TG, Brown PD, Miller RC. Systemic lupus erythematosus, radiotherapy, and the risk of acute and chronic toxicity: the Mayo Clinic Experience. Int J Radiat Oncol Biol Phys. 2008 Jun 1; 71(2):498-506. Epub 2007 Dec 31.
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  38. Gold DG, Miller RC, Pinn ME, Osborn TG, Petersen IA, Brown PD. Chronic toxicity risk after radiotherapy for patients with systemic sclerosis (systemic scleroderma) or systemic lupus erythematosus: association with connective tissue disorder severity. Radiother Oncol. 2008 Apr; 87(1):127-31. Epub 2007 Dec 26.
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  39. Gold DG, Miller RC, Petersen IA, Osborn TG. Radiotherapy for malignancy in patients with scleroderma: The Mayo Clinic experience. Int J Radiat Oncol Biol Phys. 2007 Feb 1; 67(2):559-67.
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  40. Osborn T, Lenholt L, Grosflam J. Polymyalgia rheumatica: challenges in recognition and management. Journal of Musculoskelatal Medicine. 2001; 18:83-90.
  41. Nesher G, Osborn TG, Moore TL. Effect of treatment with methotrexate, hydroxychloroquine, and prednisone on lymphocyte polyamine levels in rheumatoid arthritis: correlation with the clinical response and rheumatoid factor synthesis. Clinical & Experimental Rheumatology. 1997 Jul-Aug; 15(4):343-7.
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  42. Nesher G, Osborn TG, Moore TL. In vitro effects of methotrexate on polyamine levels in lymphocytes from rheumatoid arthritis patients. Clinical & Experimental Rheumatology. 1996 Jul-Aug; 14(4):395-9.
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  43. Mericle PM, Wilson VK, Moore TL, Hanna VE, Osborn TG, Rotskoff KS, Johnston LE Jr. Effects of polyarticular and pauciarticular onset juvenile rheumatoid arthritis on facial and mandibular growth. J Rheumatol. 1996 Jan; 23(1):159-65.
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  44. Hanna VE, Rider SF, Moore TL, Wilson VK, Osborn TG, Rotskoff KS, Johnston LE Jr. Effects of systemic onset juvenile rheumatoid arthritis on facial morphology and temporomandibular joint form and function. J Rheumatol. 1996 Jan; 23(1):155-8.
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  45. Moore TL, Osborn TG, Nesher G. Immune complexes from sera of patients with juvenile rheumatoid arthritis reveal novel 40 and 60 kd bands. Clinical & Experimental Rheumatology. 1995 Sep-Oct; 13(5):667-72.
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  46. Nesher G, Osborn TG, Moore TL. Parvovirus infection mimicking systemic lupus erythematosus. Seminars in Arthritis & Rheumatism. 1995 Apr; 24(5):297-303.
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  47. Nesher G, Hanna VE, Moore TL, Hersh M, Osborn TG. Thrombotic microangiographic hemolytic anemia in systemic lupus erythematosus. Seminars in Arthritis & Rheumatism. 1994 Dec; 24(3):165-72.
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  48. Madson KL, Moore TL, Lawrence JM 3rd, Osborn TG. Cytokine levels in serum and synovial fluid of patients with juvenile rheumatoid arthritis. J Rheumatol. 1994 Dec; 21(12):2359-63.
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  49. Ghosh S, Walters HD, Joist JH, Osborn TG, Moore TL. Adult respiratory distress syndrome associated with antiphospholipid antibody syndrome. J Rheumatol. 1993 Aug; 20(8):1406-8.
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  50. Lawrence JM III, Moore TL, Madson KL, Rejent AJ, Osborn TG. Arthropathies of cystic fibrosis: case reports and review of the literature. J Rheumatol Suppl. 1993 Jul; 38:12-5.
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  51. Bloom JN, Ni M, Moore TL, Osborn TG, Hageman GS. Serum antiocular antibodies in patients with juvenile rheumatoid arthritis. Journal of Pediatric Ophthalmology & Strabismus. 1993 Jul-Aug; 30(4):243-8.
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  52. Lawrence JM III, Moore TL, Osborn TG, Nesher G, Madson KL, Kinsella MB. Autoantibody studies in juvenile rheumatoid arthritis. Seminars in Arthritis & Rheumatism. 1993 Feb; 22(4):265-74.
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  53. Wong AK, Osborn TG, Miller JG, Wickline SA. Quantification of ventricular remodeling in the tight-skin mouse cardiomyopathy with acoustic microscopy. Ultrasound in Medicine & Biology. 1993; 19(5):365-74.
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  54. Nesher G, Moore TL, Grisanti MW, el-Najdawi E, Osborn TG. Antiperinuclear factor in juvenile rheumatoid arthritis. Ann Rheum Dis. 1992 Mar; 51(3):350-2.
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  55. Nesher G, Moore TL, Grisanti MW, el-Najdawi E, Osborn TG. Correlation of antiperinuclear factor with antibodies to streptococcal cell-wall peptidoglycan-polysaccharide polymers and rheumatoid factor. Clinical & Experimental Rheumatology. 1991 Nov-Dec; 9(6):611-5.
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  56. Nesher G, Moore TL, Osborn TG, Dorner RW. Production of IgM rheumatoid factor by normal lymphocytes after stimulation with preparations containing IgM rheumatoid factor from patients with juvenile arthritis. Ann Rheum Dis. 1991 Mar; 50(3):142-6.
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  57. Grisanti MW, Moore TL, Osborn TG, Haber PL. Eosinophilic fasciitis in children. Seminars in Arthritis & Rheumatism. 1989 Dec; 19(3):151-7.
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  58. Janosik DL, Osborn TG, Moore TL, Shah DG, Kenney RG, Zuckner J. Heart disease in systemic sclerosis. Seminars in Arthritis & Rheumatism. 1989 Dec; 19(3):191-200.
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  59. Osborn TG, Parks RL, Moore TL, Grisanti MW, Nesher G, Caciolo BA. Diflunisal versus naproxen in the management of rheumatoid arthritis. Clin Ther. 1989 Nov-Dec; 11(6):736-43.
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  60. Uchiyama RC, Osborn TG, Moore TL. Antibodies to iris and retina detected in sera from patients with juvenile rheumatoid arthritis with iridocyclitis by indirect immunofluorescence studies on human eye tissue. J Rheumatol. 1989 Aug; 16(8):1074-8.
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  61. Haber PL, Osborn TG, Moore TL. Antinuclear antibody in juvenile rheumatoid arthritis sera reacts with 50-40 kDa antigen(s) found in HeLa nuclear extracts. J Rheumatol. 1989 Jul; 16(7):949-54.
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  62. Moore TL, Osborn TG, Dorner RW. Cross-reactive antiidiotypic antibodies against human rheumatoid factors from patients with juvenile rheumatoid arthritis. Arthritis Rheum. 1989 Jun; 32(6):699-705.
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  63. Mermel LA, Osborn TG. Clostridium difficile associated reactive arthritis in an HLA-B27 positive female: report and literature review. J Rheumatol. 1989 Jan; 16(1):133-5.
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  64. Moore TL, Dorner RW, Osborn TG, Zuckner J. Hidden 19S IgM rheumatoid factors. Seminars in Arthritis & Rheumatism. 1988 Aug; 18(1):72-5.
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  65. Fairfax MJ, Osborn TG, Williams GA, Tsai CC, Moore TL. Endomyocardial biopsy in patients with systemic lupus erythematosus. J Rheumatol. 1988 Apr; 15(4):593-6.
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  66. Budd JJ III, Moore TL, Osborn TG. Complement fixing immune complexes containing antinuclear antibodies in patients with systemic lupus erythematosus. J Rheumatol. 1988 Feb; 15(2):247-50.
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  67. Moore TL, Dorner RW, Alexander RL, Osborn TG. Enzyme linked (ELISA) immunoabsorbent assay for the detection of hidden 19S IgM rheumatoid factors in juvenile rheumatoid arthritis. J Rheumatol. 1988 Jan; 15(1):87-90.
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  68. Osborn TG, Bashey RI, Moore TL, Fischer VW. Collagenous abnormalities in the heart of the tight-skin mouse. Journal of Molecular & Cellular Cardiology. 1987 Jun; 19(6):581-7.
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  69. Dorner RW, Osborn TG, Ross SC. Glycosaminoglycan composition of tight skin and control mouse skins. J Rheumatol. 1987 Apr; 14(2):295-8.
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  70. Moore TL, Osborn TG, Dorner RW. 19S IgM rheumatoid factor-7S IgG rheumatoid factor immune complexes isolated in sera of patients with juvenile rheumatoid arthritis. Pediatr Res. 1986 Oct; 20(10):977-81.
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  71. Osborn TG, Ryerse JS, Bauer NE, Urhahn JM, Blair D, Moore TL. Anticentriole antibody in a patient with progressive systemic sclerosis. Arthritis Rheum. 1986 Jan; 29(1):142-6.
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  72. Speiser JC, Moore TL, Osborn TG, Weiss TD, Zuckner J. Changing trends in pediatric septic arthritis. Seminars in Arthritis & Rheumatism. 1985 Nov; 15(2):132-8.
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  73. Baldassare AR, Weiss TD, Arthur RE, Osborn TG, Moore TL, Zuckner J. Auranofin in the treatment of rheumatoid arthritis. A two-year study. Mo Med. 1985 Nov; 82(11):711-5.
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  74. Osborn TG, Patel NJ, Moore TI, Zuckner J. Use of the HEp-2 cell substrate in the detection of antinuclear antibodies in juvenile rheumatoid arthritis. Arthritis Rheum. 1984 Nov; 27(11):1286-9.
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  75. Rosenberg GT, Ross SC, Osborn TG. Glycosaminoglycan content in the lung of the tight-skin mouse. J Rheumatol. 1984 Jun; 11(3):318-20.
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  76. Moore TL, Osborn TG, Weiss TD, Sheridan PW, Eisenwinter RK, Miller AV, Dorner RW, Zuckner J. Autoantibodies in juvenile arthritis. Seminars in Arthritis & Rheumatism. 1984 May; 13(4):329-36.
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  77. Moore TL, Oldfather JW, Osborn TG, Dorner RW, Sheridan PW, Weiss TD, Zuckner J, Rodey GE. HLA antigens in black and white patients with juvenile arthritis: associations with rheumatoid factor, hidden rheumatoid factor, antinuclear antibodies, and immune complex levels. J Rheumatol. 1984 Apr; 11(2):188-96.
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  78. Delafuente JC, Osborn TG. Review of auranofin, an oral chrysotherapeutic agent. Clin Pharm. 1984 Mar-Apr; 3(2):121-7.
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  79. Osborn TG, Bauer NE, Ross SC, Moore TL, Zuckner J. The tight-skin mouse: physical and biochemical properties of the skin. J Rheumatol. 1983 Oct; 10(5):793-6.
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  80. Ross SC, Osborn TG, Dorner RW, Zuckner J. Glycosaminoglycan content in skin of the tight-skin mouse. Arthritis Rheum. 1983 May; 26(5):653-7.
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  81. Moore TL, Dorner RW, Sheridan PW, Weiss TD, Baldassare AR, Osborn TG, Zuckner J. Longitudinal study of the presence of hidden 19S IgM rheumatoid factor in juvenile rheumatoid arthritis. J Rheumatol. 1982 Jul-Aug; 9(4):599-602.
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  82. Osborn TG, Lichtenstein JR, Moore TL, Weiss T, Zuckner J. Ehlers-Danlos syndrome presenting as rheumatic manifestations in the child. J Rheumatol. 1981 Jan-Feb; 8(1):79-85.
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PST-20222668