Adam L. Holtzman, M.D.

  1. Radiation Oncologist
  1. Liang X, Mohammadi H, Moreno KC, Beltran CJ, Holtzman AL. Heavy Ion Particle Therapy in Modern Day Radiation Oncology. Hematol Oncol Clin North Am. 2024 Dec 17 [Epub ahead of print]
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  2. Chhabra AM, Snider JW, Kole AJ, Stock M, Holtzman AL, Press R, Wang CJ, Li H, Lin H, Shi C, McDonald M, Soike M, Zhou J, Sabouri P, Mossahebi S, Colaco R, Albertini F. Proton Therapy for Spinal Tumors: A Consensus Statement From the Particle Therapy Cooperative Group. Int J Radiat Oncol Biol Phys 2024 Nov 15; 120 (4):1135-1148 Epub 2024 Aug 23
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  3. Crompton DJ, Mohammadi H, Pirgousis P, Patel S, Janus J, Zhao Y, McGee LA, Patel SH, Routman DM, Ma DJ, Holtzman AL. Elective Irradiation of Retropharyngeal Lymph Nodes as an Indication for Adjuvant Radiation Therapy After Transoral Surgery for Tonsil Cancer. Pract Radiat Oncol. 2024 Sep-Oct; 14 (5):452-456 Epub 2024 May 13
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  4. Holtzman AL, Mohammadi H, Furutani KM, Koffler DM, McGee LA, Lester SC, Gamez ME, Routman DM, Beltran CJ, Liang X. Impact of Relative Biologic Effectiveness for Proton Therapy for Head and Neck and Skull-Base Tumors: A Technical and Clinical Review. Cancers (Basel). 2024 May 21; 16 (11)
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  5. Augustin E, Holtzman AL, Dagan R, Bryant CM, Indelicato DJ, Morris CG, Deraniyagala RL, Fernandes RP, Bunnell AM, Nedrud SM, Mendenhall WM. Long-Term Outcomes Following Definitive or Adjuvant Proton Radiotherapy for Adenoid Cystic Carcinoma. Int J Part Ther. 2024 Mar; 11:100008 Epub 2024 Apr 24
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  6. Drescher NR, Indelicato DJ, Dagan R, Bradley JA, Holtzman AL, Mailhot Vega RB, Aldana PR, Sandler ES, Morris CG, Mendenhall WM. Outcomes following proton therapy for pediatric esthesioneuroblastoma. Pediatr Blood Cancer. 2024 Feb; 71 (2):e30793 Epub 2023 Nov 29
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  7. Kuan EC, Wang EW, Adappa ND, Beswick DM, London NR Jr, Su SY, Wang MB, Abuzeid WM, Alexiev B, Alt JA, Antognoni P, Alonso-Basanta M, Batra PS, Bhayani M, Bell D, Bernal-Sprekelsen M, Betz CS, Blay JY, Bleier BS, Bonilla-Velez J, Callejas C, Carrau RL, Casiano RR, Castelnuovo P, Chandra RK, Chatzinakis V, Chen SB, Chiu AG, Choby G, Chowdhury NI, Citardi MJ, Cohen MA, Dagan R, Dalfino G, Dallan I, Dassi CS, de Almeida J, Dei Tos AP, DelGaudio JM, Ebert CS, El-Sayed IH, Eloy JA, Evans JJ, Fang CH, Farrell NF, Ferrari M, Fischbein N, Folbe A, Fokkens WJ, Fox MG, Lund VJ, Gallia GL, Gardner PA, Geltzeiler M, Georgalas C, Getz AE, Govindaraj S, Gray ST, Grayson JW, Gross BA, Grube JG, Guo R, Ha PK, Halderman AA, Hanna EY, Harvey RJ, Hernandez SC, Holtzman AL, Hopkins C, Huang Z, Huang Z, Humphreys IM, Hwang PH, Iloreta AM, Ishii M, Ivan ME, Jafari A, Kennedy DW, Khan M, Kimple AJ, Kingdom TT, Knisely A, Kuo YJ, Lal D, Lamarre ED, Lan MY, Le H, Lechner M, Lee NY, Lee JK, Lee VH, Levine CG, Lin JC, Lin DT, Lobo BC, Locke T, Luong AU, Magliocca KR, Markovic SN, Matnjani G, McKean EL, Meco C, Mendenhall WM, Michel L, Na'ara S, Nicolai P, Nuss DW, Nyquist GG, Oakley GM, Omura K, Orlandi RR, Otori N, Papagiannopoulos P, Patel ZM, Pfister DG, Phan J, Psaltis AJ, Rabinowitz MR, Ramanathan M Jr, Rimmer R, Rosen MR, Sanusi O, Sargi ZB, Schafhausen P, Schlosser RJ, Sedaghat AR, Senior BA, Shrivastava R, Sindwani R, Smith TL, Smith KA, Snyderman CH, Solares CA, Sreenath SB, Stamm A, Stolzel K, Sumer B, Surda P, Tajudeen BA, Thompson LDR, Thorp BD, Tong CCL, Tsang RK, Turner JH, Turri-Zanoni M, Udager AM, van Zele T, VanKoevering K, Welch KC, Wise SK, Witterick IJ, Won TB, Wong SN, Woodworth BA, Wormald PJ, Yao WC, Yeh CF, Zhou B, Palmer JN, Adams CD, Lee JS. International Consensus Statement on Allergy and Rhinology: Sinonasal Tumors. Int Forum Allergy Rhinol. 2024 Feb; 14 (2):149-608 Epub 2024 Jan 02
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  8. Gracie J, Holtzman AL, Dagan R, Bryant CM, Morris CG, Mendenhall WM. Impact of mandated drug monitoring on opioid use during highly conformal radiotherapy for oropharynx cancer. Ann Palliat Med. 2023 Nov; 12 (6):1146-1154 Epub 2023 Oct 27
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  9. Holtzman AL, Seidensaal K, Iannalfi A, Kim KH, Koto M, Yang WC, Shiau CY, Mahajan A, Ahmed SK, Trifiletti DM, Peterson JL, Koffler DM, Vallow LA, Hoppe BS, Rutenberg MS. Carbon Ion Radiotherapy: An Evidence-Based Review and Summary Recommendations of Clinical Outcomes for Skull-Base Chordomas and Chondrosarcomas. Cancers (Basel). 2023 Oct 17; 15 (20)
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  10. Reiners K, Dagan R, Holtzman A, Bryant C, Andersson S, Nilsson R, Hong L, Johnson P, Zhang Y. CBCT-Based Dose Monitoring and Adaptive Planning Triggers in Head and Neck PBS Proton Therapy. Cancers (Basel). 2023 Jul 30; 15 (15) Epub 2023 July 30
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  11. Chhabra AM, Rice SR, Holtzman A, Choi JI, Hasan S, Press RH, Chang J, Halasz L, Tsai HK, Wang CJ, Kabolizadeh P, Gondi V, Hartsell WF, Vora SA, Vargas CE, Simone CB 2nd. Clinical outcomes and toxicities of 100 patients treated with proton therapy for chordoma on the proton collaborative group prospective registry. Radiother Oncol. 2023 Jun; 183:109551 Epub 2023 Feb 20
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  12. Holtzman AL, Dagan R, Mendenhall WM. Proton Radiotherapy for Skull-Base Malignancies: Imaging Considerations of Radiotherapy and Complications. Oral Maxillofac Surg Clin North Am. 2023 Mar 31 [Epub ahead of print]
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  13. Holtzman AL, Glassman GE, Dagan R, Rao D, Fiester PJ, Tavanaieour D, Morris CG, Indelicato DJ, Mendenhall WM. Long-term outcomes of fractionated proton beam therapy for benign or radiographic intracranial meningioma. J Neurooncol. 2023 Feb; 161 (3):481-489 Epub 2023 Jan 24
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  14. de Leo AN, Dagan R, Morris CG, Holtzman AL, Hitchcock KE, Bryant CM, Amdur RJ, Mendenhall WM. Early-stage vocal cord cancer treated with hypofractionated radiotherapy to the larynx with or without concurrent chemotherapy. Head Neck. 2022 Nov; 44 (11):2513-2521 Epub 2022 Aug 11
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  15. Holtzman AL, Rutenberg MS, De Leo AN, Rao D, Patel J, Morris CG, Indelicato DJ, Mendenhall WM. The incidence of brainstem toxicity following high-dose conformal proton therapy for adult skull-base malignancies. Acta Oncol. 2022 Aug; 61(8):1026-1031. Epub 2022 Jul 27.
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  16. Holtzman AL, Bates JE, Morris CG, Rutenberg MS, Indelicato DJ, Tavanaiepour D, Mendenhall WM. Impact of Type of Treatment Center and Access to Care on Mortality and Survival for Skull Base Chordoma and Chondrosarcoma. J Neurol Surg B Skull Base. 2022 Jun; 83(3):328-338. Epub 2021 Mar 09.
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  17. Rutenberg MS, Holtzman AL, Indelicato DJ, Huh S, Rao D, Fiester PJ, Morris CG, Tavanaiepour D, Amdur RJ. Disease Control after Radiotherapy for Adult Craniopharyngioma: Clinical Outcomes from a Large Single-Institution Series. J Neurooncol. 2022 May; 157(3):425-433. Epub 2022 Mar 12.
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  18. Mailhot Vega RB, Mohammadi H, Patel SI, Holtzman AL, Lockney NA, Lynch JW, Bansal MM, Liang X, Slayton WB, Parsons SK, Hoppe BS, Mendenhall NP. Establishing Cost-Effective Allocation of Proton Therapy for Patients With Mediastinal Hodgkin Lymphoma. Int J Radiat Oncol Biol Phys. 2022 Jan 01; 112(1):158-166. Epub 2021 Aug 02.
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  19. Liu IC, Holtzman AL, Rotondo RL, Indelicato DJ, Gururangan S, Cavaliere R, Carter B, Morris CG, Tavanaiepour D, Rutenberg MS. Proton therapy for adult medulloblastoma: Acute toxicity and disease control outcomes. J Neurooncol. 2021 Jul; 153(3):467-476. Epub 2021 Jun 08.
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  20. Holtzman AL, Rotondo RL, Rutenberg MS, Indelicato DJ, De Leo A, Rao D, Patel J, Morris CG, Mendenhall WM. Clinical Outcomes Following Dose-Escalated Proton Therapy for Skull-Base Chordoma. Int J Part Ther. 2021 Summer; 8(1):179-188. Epub 2021 Jun 25.
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  21. Dagan R, Uezono H, Bryant C, Holtzman AL, Morris CG, Mendenhall WM. Long-term Outcomes from Proton Therapy for Sinonasal Cancers. Int J Part Ther. 2021 Summer; 8 (1):200-212 Epub 2021 June 25
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  22. Bryant CM, Dagan R, Holtzman AL, Fernandes R, Bunnell A, Mendenhall WM. Passively Scattered Proton Therapy for Nonmelanoma Skin Cancer with Clinical Perineural Invasion. Int J Part Ther. 2021 Summer; 8 (1):285-293 Epub 2021 June 25
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  23. De Leo AN, Holtzman AL, Ho MW, Morris CG, Rutenberg MS, Rotondo RL, Bates JE, Indelicato DJ, Rao D, Asa Hasan M, Mendenhall WM. Vision loss following high-dose proton-based radiotherapy for skull-base chordoma and chondrosarcoma. Radiother Oncol. 2021 May; 158:125-130. Epub 2021 Feb 19.
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  24. Indelicato DJ, Rotondo RL, Mailhot Vega RB, Holtzman AL, Looi WS, Morris CG, Sandler ES, Aldana PR, Bradley JA. Local Control After Proton Therapy for Pediatric Chordoma. Int J Radiat Oncol Biol Phys. 2021 Apr 1; 109 (5):1406-1413 Epub 2020 Nov 27
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  25. Mendenhall WM, Holtzman AL, Dagan R, Bryant CM, Hitchcock KE, Amdur RJ, Fernandes RP. Current Role of Radiotherapy in the Management of Oral Cavity Squamous Cell Carcinoma. Craniomaxillofac Trauma Reconstr. 2021 Mar; 14 (1):79-83 Epub 2020 Nov 03
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  26. Soule E, Baig S, Fiester P, Holtzman A, Rutenberg M, Tavanaiepour D, Rao D. Current Management and Image Review of Skull Base Chordoma: What the Radiologist Needs to Know. J Clin Imaging Sci. 2021; 11:46. Epub 2021 Aug 30.
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  27. Way AR, Fiester P, Holtzman A, Rao D. A Case of Carotid Body Tumor with Perineural Tumor Spread along the Superior Laryngeal Nerve. J Clin Imaging Sci. 2021; 11:6. Epub 2021 Feb 09.
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  28. Amdur RJ, Dagan R, Holtzman A, Yeung AR, Hitchcock KE, Mendenhall WM. A format for dosimetry comparison studies. Med Dosim. 2020 Winter; 45 (4):382-383 Epub 2020 July 09
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  29. Rutenberg MS, Rotondo RL, Rao D, Holtzman AL, Indelicato DJ, Huh S, Morris CG, Mendenhall WM. Clinical outcomes following proton therapy for adult craniopharyngioma: a single-institution cohort study. J Neurooncol. 2020 Apr; 147(2):387-395. Epub 2020 Feb 21.
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  30. Holtzman AL, Mendenhall WM. High-dose conformal proton therapy for clinical perineural invasion in cutaneous head and neck cancer. Oral Oncol. 2020 Jan; 100:104486 Epub 2019 Dec 05
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  31. Rao D, Fiester P, Patel J, Rutenberg M, Holtzman A, Dagan R, Rotondo RL, Sandhu SJS. Multidisciplinary Imaging Review Conference Improves Neuro-oncology Radiation Treatment Planning and Follow-up. Cureus. 2019 Oct 10; 11(10):e5882.
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  32. Holtzman AL, Bryant CM, Mendenhall NP, Mendenhall WM, Nichols RC, Henderson RH, Figura N, Morris CG, Williams CR, Li Z, Hoppe BS. Patient-Reported Sexual Survivorship Following High-Dose Image-Guided Proton Therapy for Prostate Cancer. Radiother Oncol. 2019 May; 134:204-210. Epub 2019 Feb 27.
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  33. Holtzman AL, Rotondo RL, Rutenberg MS, Indelicato DJ, Mercado CE, Rao D, Tavanaiepour D, Morris CG, Louis D, Flampouri S, Mendenhall WM. Proton therapy for skull-base chondrosarcoma, a single-institution outcomes study. J Neurooncol. 2019 May; 142(3):557-563. Epub 2019 Mar 02.
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  34. Mercado CE, Holtzman AL, Rotondo R, Rutenberg MS, Mendenhall WM. Proton therapy for skull base tumors: A review of clinical outcomes for chordomas and chondrosarcomas. Head Neck. 2019 Feb; 41 (2):536-541 Epub 2018 Dec 07
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  35. Holtzman AL, Stahl JM, Zhu S, Morris CG, Hoppe BS, Kirwan JE, Mendenhall NP. Does the Incidence of Treatment-Related Toxicity Plateau After Radiation Therapy: The Long-Term Impact of Integral Dose in Hodgkin's Lymphoma Survivors. Adv Radiat Oncol. 2019 Oct-Dec; 4(4):699-705. Epub 2019 Jul 23.
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  36. Holtzman AL, Williams JP, Hutchinson DF, Morris CG, Yeung AR. Improving Patient-reported Pain During Radiotherapy Through Nurse Involvement and Patient Education. Am J Clin Oncol. 2018 Oct; 41 (10):1028-1030
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  37. Holtzman AL, Pereira DB, Yeung AR. Implementation of depression and anxiety screening in patients undergoing radiotherapy. BMJ Open Qual. 2018; 7 (2):e000034 Epub 2018 May 07
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  38. Begosh-Mayne D, Holtzman A, Amdur RJ, Dziegielewski P, Mendenhall WM. Radiotherapy for Polymorphous Low-grade Adenocarcinoma of the Head and Neck Hong Kong K Radiol. 2018; 21:121-3.
  39. Holtzman A, Morris CG, Amdur RJ, Dziegielewski PT, Boyce B, Mendenhall WM. Outcomes after primary or adjuvant radiotherapy for salivary gland carcinoma. Acta Oncol. 2017 Mar; 56 (3):484-489 Epub 2016 Nov 16
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  40. Holtzman AL, Hitchcock K. IMAGES IN CLINICAL MEDICINE. Human Papillomavirus-Associated Oropharyngeal Squamous-Cell Carcinoma. N Engl J Med. 2016 Sep 29; 375 (13):1269
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  41. Holtzman AL, Hoppe BS, Letter HP, Bryant C, Nichols RC, Henderson RH, Mendenhall WM, Morris CG, Williams CR, Li Z, Mendenhall NP. Proton Therapy as Salvage Treatment for Local Relapse of Prostate Cancer Following Cryosurgery or High-Intensity Focused Ultrasound. Int J Radiat Oncol Biol Phys. 2016 May 01; 95(1):465-471. Epub 2015 Dec 19.
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  42. Sachsman S, Hoppe BS, Mendenhall NP, Holtzman A, Li Z, Slayton W, Joyce M, Sandler E, Flampouri S. Proton therapy to the subdiaphragmatic region in the management of patients with Hodgkin lymphoma. Leuk Lymphoma. 2015 Jul; 56(7):2019-24. Epub 2014 Nov 19.
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  43. Holtzman A, Hoppe BS, Li Z, Slayton W, Sandler E, Joyce M, Ozdemir S, Mendenhall NP, Flampouri S. Advancing the Therapeutic Index of Pediatric Patients with Stage III Hodgkin Lymphoma with Proton Therapy International Journal of Particle Therapy. 2014; 1(2):343-356.
  44. Holtzman AL, Babinski D, Merlo LJ. Knowledge and attitudes toward hookah usage among university students. J Am Coll Health. 2013; 61 (6):362-70
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