Research

Mayo Clinic researchers have a rich history in advancing precision medicine for breast cancer. Projects include:

  • Finding new therapies for breast cancer
  • Identifying an enzyme that regulates DNA repair
  • Identifying subsets of women who do not benefit from cancer drugs called aromatase inhibitors
  • Identifying genetic variations in the enzyme CYP2D6, which helps explain why some people with breast cancer don't respond to tamoxifen
  • Developing a new drug to replace tamoxifen for people with low CYP2D6 enzyme activity
  • Developing a new drug for women with resistance to aromatase inhibitors
  • Identifying mechanisms for why some people do not respond to endocrine treatment, and then developing a new drug for breast cancer

Publications

See a list of publications by Mayo Clinic doctors on precision medicine for breast cancer on PubMed, a service of the National Library of Medicine.

Read more about breast cancer research laboratories and programs:

  1. Center for Individualized Medicine
  2. Breast Cancer SPORE
By Mayo Clinic Staff