Mayo Clinic's approach
Mayo Clinic has one of the largest transplant practices in the United States. Our transplant doctors, surgeons and other transplant staff members at the Mayo Clinic campuses in Arizona, Florida and Minnesota have extensive experience with living-donor kidney and liver transplantation.
The living-donor process at Mayo Clinic starts with completing a health history questionnaire.
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Team approach. Mayo Clinic's integrated teams of surgeons, doctors, transplant nurses, pharmacists and others work together to provide your care, from your evaluation through post-surgery care.
The transplant team will evaluate you to determine if you can donate a kidney or part of your liver. You'll have blood tests as well as a thorough physical examination and psychological evaluation. Several other tests, including detailed imaging of your liver or kidneys, will be performed to ensure that you're in good health and you meet donation criteria.
After you donate an organ, living-donor coordinators and other transplant staff members will offer you support and follow-up care for several months after your surgery.
- Coordinated care. Having all of this subspecialized expertise in a single place, focused on you, means that you're not just getting one opinion — your care is discussed among the team, your test results are available quickly, appointments are scheduled in coordination, and your transplant care team works together to determine what may be most appropriate for you.
- Surgical expertise. Mayo Clinic surgeons perform living-donor transplant surgery for liver transplant and kidney transplant. Surgeons perform minimally invasive surgery to remove a living donor's kidney (laparoscopic donor nephrectomy) for a kidney transplant, which is less painful and has a shorter recovery time for the donor compared with open surgery.
- Research. Mayo Clinic researchers actively study the health of donors after transplant surgery to improve results. At Mayo Clinic, you may have access to ongoing clinical trials, research and new treatments as part of your living-donor transplantation experience.
Expertise and rankings
Experience
Mayo Clinic surgeons have extensive experience performing living-donor transplant surgery for liver transplant and kidney transplant.
Transplant leader
Mayo Clinic has one of the largest living-donor kidney and liver transplant programs in the United States.
Across its three sites, Mayo Clinic surgeons have performed more than 16,500 kidney transplants. They currently perform about 1,000 kidney transplants each year, including many from living kidney donors.
Mayo Clinic surgeons perform more than 500 liver transplants each year among its three campuses, including many from living liver donors.
Advanced treatment and technology
Mayo Clinic surgeons have extensive expertise with all types of living-donor transplant surgeries, including minimally invasive procedures, HIV-positive organ donation, paired-organ donation and other complex procedures.
Innovation and research
Mayo Clinic transplant researchers take a leading role in efforts to find new, improved ways to conduct all aspects of transplantation, improve the experience of donation, reduce risks and improve the outcomes of transplantation.
The Mayo Clinic Transplant Center supports many studies for living-donor transplant research.
Nationally recognized expertise
Mayo Clinic in Rochester, Minnesota, ranks No. 1 for diabetes and endocrinology in the U.S. News & World Report Best Hospitals rankings. Mayo Clinic in Phoenix/Scottsdale, Arizona, and Mayo Clinic in Jacksonville, Florida, are ranked among the Best Hospitals for diabetes and endocrinology by U.S. News & World Report.
Mayo Clinic in Rochester, Minnesota, ranks No. 1 for digestive disorders in the U.S. News & World Report Best Hospitals rankings. Mayo Clinic in Phoenix/Scottsdale, Arizona, and Mayo Clinic in Jacksonville, Florida, are ranked among the Best Hospitals for digestive disorders by U.S. News & World Report. Mayo Clinic Children's Center in Rochester is ranked the No. 1 hospital in Minnesota, and the five-state region of Iowa, Minnesota, North Dakota, South Dakota and Wisconsin, according to U.S. News & World Report's 2024–2025 "Best Children's Hospitals" rankings.
Locations, travel and lodging
Mayo Clinic has major campuses in Phoenix and Scottsdale, Arizona; Jacksonville, Florida; and Rochester, Minnesota. The Mayo Clinic Health System has dozens of locations in several states.
For more information on visiting Mayo Clinic, choose your location below:
Costs and insurance
Mayo Clinic has dedicated transplant financial services representatives and social workers who can assist you with insurance and financial questions regarding your living organ donation.
Mayo Clinic works with hundreds of insurance companies and is an in-network provider for millions of people. In most cases, Mayo Clinic doesn't require a physician referral. Some insurers require referrals or may have additional requirements for certain medical care. Many insurance companies require you to get preapproval authorization prior to transplant services.
For international patients
Mayo Clinic has dedicated international patient account representatives who can assist you with questions regarding your costs and insurance. Read more about international financial services.
Case managers
Mayo Clinic financial staff will work closely with your case managers from your insurance company. Your case manager, who is assigned to you, is available to answer questions and calls related to your insurance costs.