A high red blood cell count is an increase in a type of cells made in bone marrow and found in blood. The main job of red blood cells is to move oxygen from the lungs to the rest of the body. A condition that limits oxygen can cause a rise in red blood cell count. Other conditions can cause the body to make more red blood cells than it needs.
What's considered a high red blood cell count is different at different labs. For adults, the usual range is generally 4.35 to 5.65 million red blood cells per microliter (mcL) of blood for men and 3.92 to 5.13 million red blood cells per mcL of blood for women. In children, what's thought of as high depends on age and sex.
Low oxygen levels, misuse of certain drugs and blood cancers can cause a high red blood cell count.
A high red blood cell count is most often found when a health care provider is doing tests to find the cause of symptoms or check for changes in certain illnesses. Your provider can talk to you about what test results mean.
Show References
- Tefferi A. Diagnostic approach to the patient with polycythemia. https://www.uptodate.com/contents/search. Accessed Oct. 26, 2022.
- CBC with differential, blood. Mayo Medical Laboratories. http://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/9109. Accessed Oct. 26, 2022.
- Weitz M, et al. Blood. In The Big Picture Physiology: Medical Course & Step 1 Review. 2nd ed. McGraw Hill; 2020. https://accessmedicine.mhmedical.com. Accessed Oct. 26, 2022.
- Walls RM, et al., eds. Anemia and polycythemia. In: Rosen's Emergency Medicine: Concepts and Clinical Practice. 10th ed. Elsevier; 2023. http://www.clinicalkey.com. Accessed Oct. 26, 2022.
- Loscalzo J, et al. Anemia and polycythemia. In: Harrison's Principles of Internal Medicine. 21st ed. McGraw Hill; 2022. https://accessmedicine.mhmedical.com. Accessed Oct. 26, 2022.
- Zhong F, et al. Red blood cell count: An unrecognized risk factor for nonalcoholic fatty liver disease. Frontiers in Endocrinology. 2021; doi:10.3389/fendo.2021.760981.
Feb. 10, 2023Original article: https://www.mayoclinic.org/symptoms/high-red-blood-cell-count/basics/definition/SYM-20050858