A low white blood cell count is a lower number of the cells in the blood that fight illness.

What's thought of as low in a white blood cell count varies from one lab to another. This is because labs set their own reference ranges based on the people they serve. Most often, a count lower than 3,500 white blood cells per microliter of blood is thought to be low for adults. For children, an expected count depends on the age.

Some people can have white blood cell counts that are lower without being ill. For instance, Black people tend to have lower counts than white people do.

From Mayo Clinic to your inbox

Sign up for free and stay up to date on research advancements, health tips, current health topics, and expertise on managing health. Click here for an email preview.

We use the data you provide to deliver you the content you requested. To provide you with the most relevant and helpful information, we may combine your email and website data with other information we have about you. If you are a Mayo Clinic patient, we will only use your protected health information as outlined in our Notice of Privacy Practices. You may opt out of email communications at any time by clicking on the unsubscribe link in the email.

Feb. 19, 2026