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1. A Study of Obeticholic Acid Evaluating Clinical Outcomes in Patients with Primary Biliary Cirrhosis

   Primary biliary cirrhosis is a serious, life-threatening, bile acid related liver disease of unknown cause. Without treatment, it frequently progresses to liver ...

2. A Study to Evaluate The Effectiveness and Safety of Abrocitinib, with or without Topical Medications, in Subjects Aged 12 Years and Older with Moderate-to-Severe Atopic Dermatitis - Mayo Clinic

   Patients who meet safety step-down criteria will have their dose reduced once, from 200 mg QD to 100 mg QD, or from 100 mg QD to placebo. Participation ...

3. Alpha-1 AD Carriers and Lung Cancer Risk - Mayo Clinic

   About this study. The purpose of this study is to collect medical and family histories, blood and/or tumor tissue samples from patients who are being tested ...

4. A Study to Collect and Correlate the Data from Multiple Risk Assessments for Heart Toxicity in Patients Receiving Chemotherapy for Breast Cancer - Mayo Clinic

   The purpose of this study is to collect and correlate the data from various cardiovascular risk asessments to successfully measure the risk of heart toxicity in ...

5. Barriers to Pre-emptive Renal Transplantation - Mayo Clinic

   The specific purpose of this study is to compare the characteristics of patients at Mayo Clinic Rochester who received a living donor kidney transplant here ...

6. A Study to Evaluate the Effect of 1,25-Dihydroxyvitamin D3 to Treat Insulin Secretion and Muscle Strength in Pre-diabetics - Mayo Clinic

   The purpose of this study is to assess the effects of 1,25(OH)2D3 on insulin secretion by the pancreas and glucose utilization by skeletal muscle, as well as to ...

7. Atezolizumab, Pemetrexed Disodium, Cisplatin, and Surgery With or Without Radiation Therapy in Treating Patients With Stage I-III Pleural Malignant Mesothelioma - Mayo Clinic

   b. To evaluate overall survival in patients with resectable malignant pleural mesothelioma treated with a regimen of neoadjuvant cisplatin-pemetrexed- ...

8. A Study to Assess Glycemic Variability and Fluctuations in Cognitive Status in Adults with Type 1 Diabetes - Mayo Clinic

   The objective for thisstudy is to characterize the impact of glycemic excursions on cognition in Type 1 Diabetes (T1D) and determine mediators and moderators of ...

9. A Study of Circulating Nucleic Acid Tumor Markers Found in Different Components of Blood - Mayo Clinic

   The purpose of this study is to assess for the circulating nucleic acid tumor markers dispersed in the various components of blood samples from patients with ...

10. A Study to Evaluate Alzheimer Disease Biomarkers in Cerebrospinal Fluid (CSF) - Mayo Clinic

    The purpose of this study is to validate the Alzheimer Disease Biomarkers assays (Phospho-Tau/Total-Tau/Ab42) being implemented at Mayo to compare them to the ...