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  1. Pembrolizumab, Combination Chemotherapy, and Radiation Therapy Before Surgery in Treating Adult Patients With Locally Advanced Gastroesophageal Junction or Gastric Cardia Cancer That Can Be Removed by Surgery - Mayo Clinic

    Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. Giving pembrolizumab, combination chemotherapy, and radiation therapy before ...

  2. Quantitation of McArdle's Sign and Evaluation of Specificity for Multiple Sclerosis - Mayo Clinic

    The study is designed to quantitate McArdle's sign, an increase in measurable weakness with neck flexion described in patients with multiple sclerosis, and to ...

  3. Everolimus, Rituximab, and Combination Chemotherapy in Treating Patients with Newly Diagnosed Untreated Diffuse Large B-Cell Lymphoma - Mayo Clinic

    RATIONALE: Everolimus may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Monoclonal antibodies, such as rituximab, can ...

  4. A Study to Evaluate a Standard-dose and High- dose Regimen of Encorafenib + Binimetinib in Patients with BRAFV600-mutant Melanoma Brain Metastasis - Mayo Clinic

    The purpose of this study is to assess the safety, effectiveness and pharmacokinetic (PK) of 2 dosing regimens of encorafenib + binimetinib combination in ...

  5. Immunologic and Biochemical Characterization of IgG4-related Disease - Mayo Clinic

    About this study. IgG4-related disease is a recently recognized disease that can mimic other diseases and that can be difficult to diagnose.

  6. A Study to Establish a Multi-focal Registry for Ground Glass Opacities - Mayo Clinic

    The purpose of this study is to establish a registry for the active surveillance of patients with multiple ground glass opacities (GGOs) in the lung identified ...

  7. Gemcitabine and Cisplatin as Neoadjuvant Chemotherapy in Patients With High-Grade Upper Tract Urothelial Carcinoma - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  8. A Study to Compare the Effectiveness of Invasive versus Conservative Medical Approaches in Patients with Stable Ischemic Heart Disease and Advanced Chronic Kidney Disease - Mayo Clinic

    About this study. The purpose of the ISCHEMIA-CKD trial is to determine the best management strategy for patients with stable ischemic heart disease (SIHD), ...

  9. A Study of the Effect of Using MRI and Mammography Before Surgery in Patients with Stage I-II Breast Cancer - Mayo Clinic

    The purpose of this study is to assess whether patients undergoing a breast MRI (magnetic resonance imaging) before breast surgery will have better results ...

  10. Risk Prediction for Immune Checkpoint Inhibitor Associated Diabetes Mellitus - Mayo Clinic

    About this study. The purpose of this study is to identify risk factors for ICI associated diabetes mellitus and to assess the severity and natural course ...