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1. Brentuximab Vedotin in Patients With CD30-positive Nonlymphomatous Malignancies - Mayo Clinic

   About this study. This is an open-label, multicenter, phase 2 clinical trial to evaluate the antitumor activity of brentuximab vedotin as a single agent in ...

2. At-Home Self-Collection for Pre-Transplant Patients - Mayo Clinic

   The objectives of this study are to determine whether adequate blood volumes can be obtained with the Tasso+ device for anti-HLA antibody testing, to compare ...

3. A Multi-Center Study Evaluating KTE-X19 in Pediatric and Adolescent Subjects With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia - Mayo Clinic

   This is a single arm, open-label, multi-center, phase 1/2 study, to determine the safety and efficacy of KTE-X19, an autologous anti-CD19 chimeric antigen ...

4. A Study to Evaluate Setmelanoitide to Treat Patients with Rare Genetic Disorders of Obesity - Mayo Clinic

   The purpose of this study is to explore the impact of Setmelanotide on obesity in patients with various specific rare genetic mutations. Participation ...

5. An Open-label Study to Assess the Anti-Tumor Activity and Safety of REGN1979, an Anti-CD20 X Anti-CD3 Bispecific Antibody, in Patients with Relapsed or Refractory B-cell Non-Hodgkin Lymphoma - Mayo Clinic

   An Open-label Study to Assess the Anti-Tumor Activity and Safety of REGN1979, an Anti-CD20 X Anti-CD3 Bispecific Antibody, in Patients with Relapsed or ...

6. Upifitamab Rilsodotin Maintenance in Platinum-Sensitive Recurrent Ovarian Cancer (UP-NEXT) - Mayo Clinic

   Patients with recurrent, platinum-sensitive high-grade serous ovarian cancer (HGSOC) including fallopian tube and primary peritoneal cancer expressing high ...

7. Understanding Post-Traumatic Headache: Forward Translation of a Posttraumatic Headache Animal Model to Posttraumatic Headache in the Human - Mayo Clinic

   Although posttraumatic headache (PTH) shares some clinical characteristics with primary headache disorders, such as migraine, there are many unique features ...

8. Development of an EEG Diagnostic for Repetitive Sub-concussive Head Impacts - Mayo Clinic

   The purpose of this study is to build on previous work, replicating the experimental protocol for subconcussive intervention with soccer headers, while adding ...

9. Bioengineered Cardiac Tissue for Cardioyopathy Analysis - Mayo Clinic

   The purpose of this study is to produce and characterize patient-specific cardiac tissue for cardiomyopathy using reprogrammed cell technology. Participation ...

10. A Study of the Underlying Physical Characteristics of a Graft Leading to Survival in Liver Transplant - Mayo Clinic

    About this study. The purpose of this study is to evaluate genes collected comparing a recipient's serum, a recipient's original liver and the donor liver ...