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Jacksonville, FL: FL 904-953-0853
Phoenix/Scottsdale, AZ: AZ 480-301-8484
Rochester, MN: MN 507-538-3270

Choose the Latest Innovations in Mouth Cancer Treatment

You can find the answers you have been looking for with Mayo Clinic’s team of mouth cancer experts, who will work together to understand your goals and meet your needs as a whole person.

At Mayo Clinic, you will have access to comprehensive head and neck cancer expertise, and these experts from across disciplines come together for one specific goal—to focus on you. Mayo Clinic Head and Neck Cancer Center treats all types of head and neck and skull base cancers, including mouth cancer.

Your expert team will customize your treatment plan by working in close collaborations that may include ear, nose and throat (ENT) specialists, surgeons, medical oncologists, radiation oncologists, pathologists, radiologists, speech therapists, and other professionals. Your plan will be based on the size, stage, and HPV status of your cancer. Test results are made available quickly, and your appointments are coordinated so you can get answers in a matter of days.

Mouth cancer refers to cancer that develops in any of the parts that make up the mouth or oral cavity. Increasingly, mouth cancers are associated with human papillomavirus (HPV), which has a profound effect on the prognosis and treatment of the cancer. Mouth cancer can occur on the:

  • Lips
  • Gums
  • Tongue
  • Inner lining of the cheeks
  • Roof of the mouth
  • Floor of the mouth (under the tongue)

Mayo Clinic experts and surgeons can offer the latest advances and innovations in mouth cancer. Additionally, your team may also recommend chemotherapy, immunotherapy, advanced radiation techniques, including proton or intensity-modulated radiation therapy, depending on the stage of your diagnosis.

Mayo Clinic is top-ranked in more specialties than any other hospital, according to U.S. News & World Report. Mayo Clinic's otolaryngology (ear, nose and throat) and cancer practices are also ranked among the best in the country.

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Jacksonville, FL: 904-953-0853
Phoenix/Scottsdale, AZ: 480-301-8484
Rochester, MN: 507-538-3270

(SINGING) Amazing grace-- All the things that we think of give us personality and individuality in life really reside in the head and neck. There have actually been studies done looking at patients who get treated at centers who do a high volume at head and neck cases. Patients who go to physicians who do this as a dedicated specialty tend to do better. We specialize in rare cancers, so that they're common for us. You come and see me, but instantly, you see a whole team of people. Our multidisciplinary group, our collaboration, I would say, sets us apart from everybody else. And not to mention the fact that we just have all of the newest tools to do this. The surgical robot allows you to get into tight spaces with what is called minimally invasive surgery. We have a very state of the art proton unit, able to deliver a very tight radiation field and avoid normal structures. We're probably one of the most aggressive centers in looking at dose deescalation in terms of radiation for patients with the HPV-related oropharynx cancers. 90% of the people with papillomavirus-induced tumor are cured by treatment. They can do very well with minimally invasive surgery and a decreased dose of targeted radio therapy and maybe targeted chemotherapy, and still have a high cure rate. [MUSIC PLAYING]

It was reassuring to know that whatever happened, it would be taken care of at Mayo.

— Susan

Why Choose Mayo Clinic?

  • More Experience

    Every year, more than 1 million people come to Mayo Clinic for care. Mayo Clinic's highly specialized experts are experienced in treating rare and complex conditions.

  • The Right Answers

    Getting effective treatment depends on identifying the right problem. In a recent study, 88 percent of patients who came to Mayo Clinic for a second opinion received a new or refined diagnosis.

  • Seamless Care

    At Mayo Clinic, every aspect of care is coordinated and teams of experts work together to provide exactly the care each patient needs. What might take months elsewhere is often done in days at Mayo Clinic

  • Unparalleled Expertise

    Mayo Clinic experts are some of the best in the world. Mayo Clinic consistently ranks among the top hospitals in the nation in the annual U.S. News & World Report rankings of best hospitals.