Monosodium glutamate, also called MSG, is used to make food taste better. Glutamate is a form of the amino acid glutamic acid. Both are naturally in food such as cheese, tomatoes, mushrooms and meat. Glutamate is not related to gluten.
The U.S. Food and Drug Administration, also called FDA, lists MSG as a food ingredient that's safe to eat in typical amounts. But some people may react to MSG. For that reason, when MSG is added to food, the FDA says it must be listed on the label.
These reactions, called MSG symptom complex, are not allergic reactions. They may include:
- Headache.
- Visual aura without headache.
- Flushing.
- Body tingling.
- Quick, fluttering heartbeats, called palpitations.
- Chest pain or heaviness.
- Feeling sick to the stomach, called nausea.
- Muscle aches.
Researchers have found no clear proof of a link between MSG and these symptoms. But some people may have short-term reactions to MSG. Symptoms are often mild and don't need to be treated. To prevent a reaction, don't eat foods that have MSG in them.
Show References
- Simon RA. Allergies and asthmatic reactions to food additives. https://www.uptodate.com/contents/search. Accessed Dec. 6, 2024.
- AskMayoExpert. Visual migraine aura without headache (ophthalmic migraine). Mayo Clinic; 2024.
- Burke AW, et al. Reactions to food and drug additives. In: Middleton's Allergy: Principles and Practice. 9th ed. Elsevier; 2020. https://www.clinicalkey.com. Accessed Dec. 6, 2024.
- Duyff RL. Academy of Nutrition and Dietetics Complete Food and Nutrition Guide. 5th ed. Kindle edition. Houghton Mifflin Harcourt; 2017. Accessed Dec. 18, 2024.
- Questions and answers on monosodium glutamate (MSG). U.S. Food and Drug Administration. http://www.fda.gov/food/ingredientspackaginglabeling/foodadditivesingredients/ucm328728.htm. Accessed Dec. 9, 2024.
Feb. 27, 2025Original article: https://www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/expert-answers/monosodium-glutamate/faq-20058196