When ACE inhibitors are used

ACE inhibitors are used to prevent, treat or improve symptoms in conditions such as:

• High blood pressure, also called hypertension.
• Coronary artery disease.
• Heart failure.
• Diabetes.
• Certain chronic kidney diseases.
• Heart attacks.
• Scleroderma, a disease that involves hardening of the skin and connective tissues.
• Migraines.

Sometimes, another blood pressure medicine, such as a diuretic or calcium channel blocker, is used with an ACE inhibitor. ACE inhibitors should not be taken with an angiotensin receptor blocker, an angiotensin receptor neprilysin inhibitor or a direct renin inhibitor.