Elaine C. Wirrell, M.D.
Neurologist
Pediatrician
Ramantani G,
Wirrell E
. Epilepsy surgery in developmental and epileptic encephalopathies. Epilepsy Behav. 2024 Aug 23; 159:109985 [Epub ahead of print]
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Conecker G, Xia MY, Hecker J, Achkar C, Cukiert C, Devries S, Donner E, Fitzgerald M, Gardella E, Hammer M, Hegde A, Hu C, Kato M, Luo T, Schreiber JM, Wang Y, Kooistra T, Oudin M, Waldrop K, Youngquist JT, Zhang D,
Wirrell E
, Perry MS. Global modified-Delphi consensus on comorbidities and prognosis of SCN8A-related epilepsy and/or neurodevelopmental disorders. Epilepsia. 2024 Aug; 65 (8):2308-2321 Epub 2024 May 27
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Conecker G, Xia MY, Hecker J, Achkar C, Cukiert C, Devries S, Donner E, Fitzgerald MP, Gardella E, Hammer M, Hegde A, Hu C, Kato M, Luo T, Schreiber JM, Wang Y, Kooistra T, Oudin M, Waldrop K, Youngquist JT, Zhang D,
Wirrell E
, Perry MS. Global modified Delphi consensus on diagnosis, phenotypes, and treatment of SCN8A-related epilepsy and/or neurodevelopmental disorders. Epilepsia. 2024 Aug; 65 (8):2322-2338 Epub 2024 May 27
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Wirrell EC
. Overview of clinical and physiologic aspects of status epilepticus in the developmental and epileptic encephalopathies. Epilepsy Behav. 2024 Jul 26; 159:109950 Epub 2024 July 26
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Wirrell EC
, Lagae L, Scheffer IE, Cross JH, Specchio N, Strzelczyk A. Practical considerations for the use of fenfluramine to manage patients with Dravet syndrome or Lennox-Gastaut syndrome in clinical practice. Epilepsia Open. 2024 Jul 4 Epub 2024 July 04
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Bacq A, Depaulis A, Castagne V, Le Guern ME,
Wirrell EC
, Verleye M. An Update on Stiripentol Mechanisms of Action: A Narrative Review. Adv Ther. 2024 Apr; 41 (4):1351-1371 Epub 2024 Mar 05
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Reed L, Ciliberto M, Fong SL, Nickels K, Kossoff E,
Wirrell E
, Joshi C. Efficacy of felbamate in a cohort of patients with epilepsy with myoclonic atonic seizures (EMAtS). Epilepsy Res. 2024 Mar; 201:107314 Epub 2024 Feb 02
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Perucca E, French JA, Aljandeel G, Balestrini S, Braga P, Burneo JG, Felli AC, Cross JH, Galanopoulou AS, Jain S, Jiang Y, Kalviainen R, Lim SH, Meador KJ, Mogal Z, Nabbout R, Sofia F, Somerville E, Sperling MR, Triki C, Trinka E, Walker MC, Wiebe S, Wilmshurst JM,
Wirrell E
, Yacubian EM, Kapur J. Which terms should be used to describe medications used in the treatment of seizure disorders? An ILAE position paper. Epilepsia. 2024 Mar; 65 (3):533-541 Epub 2024 Jan 27
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Perry MS, Scheffer IE, Sullivan J, Brunklaus A, Boronat S, Wheless JW, Laux L, Patel AD, Roberts CM, Dlugos D, Holder D, Knupp KG, Lallas M, Phillips S, Segal E, Smeyers P, Lal D,
Wirrell E
, Zuberi S, Brunger T, Wojnaroski M, Maru B, O'Donnell P, Morton M, James E, Vila MC, Huang N, Gofshteyn JS, Rico S. Severe communication delays are independent of seizure burden and persist despite contemporary treatments in SCN1A+ Dravet syndrome: Insights from the ENVISION natural history study. Epilepsia. 2024 Feb; 65 (2):322-337 Epub 2023 Dec 22
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Sullivan J,
Wirrell E
, Knupp KG, Chen D, Flamini R, Zafar M, Ventola P, Avendano J, Wang F, Parkerson KA, Ticho B. Adaptive functioning and neurodevelopment in patients with Dravet syndrome: 12-month interim analysis of the BUTTERFLY observational study. Epilepsy Behav. 2024 Feb; 151:109604 Epub 2024 Jan 13
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Stefanos-Yakoub I, Wingeier K, Held U, Latal B,
Wirrell E
, Smith ML, Ramantani G. Long-term intellectual and developmental outcomes after pediatric epilepsy surgery: A systematic review and meta-analysis. Epilepsia. 2024 Feb; 65 (2):251-265 Epub 2023 Dec 09
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Reilly C, Jette N, Johnson EC, Kariuki SM, Meredith F,
Wirrell E
, Mula M, Smith ML, Walsh S, Fong CY, Wilmshurst JM, Kerr M, Valente K, Auvin S. Scoping review and expert-based consensus recommendations for assessment and management of psychogenic non-epileptic (functional) seizures (PNES) in children: A report from the Pediatric Psychiatric Issues Task Force of the International League Against Epilepsy. Epilepsia. 2023 Dec; 64 (12):3160-3195 Epub 2023 Oct 07
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Vasquez A,
Wirrell E
. Optimizing therapy in Dravet syndrome: Why the wait? Dev Med Child Neurol 2023 Dec; 65 (12):1545-1546 Epub 2023 May 17
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Vasquez A, Hilliker DR,
Wirrell EC
. Pediatric psychogenic non-epileptic seizures: A retrospective observational cohort study at a quaternary center. Epilepsy Behav. 2023 Sep; 146:109359 Epub 2023 July 25
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Smith KM,
Wirrell EC
, Andrade DM, Choi H, Trenite DK, Jones H, Knupp KG, Mugar J, Nordli DR Jr, Riva A, Stern JM, Striano P, Thiele EA, Zawar I. Management of epilepsy with eyelid myoclonia: Results of an international expert consensus panel. Epilepsia. 2023 Sep; 64 (9):2342-2350 Epub 2023 June 23
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Smith KM,
Wirrell EC
, Andrade DM, Choi H, Trenite DK, Jones H, Knupp KG, Mugar J, Nordli DR Jr, Riva A, Stern JM, Striano P, Thiele EA, Zawar I. Clinical presentation and evaluation of epilepsy with eyelid myoclonia: Results of an international expert consensus panel. Epilepsia. 2023 Sep; 64 (9):2330-2341 Epub 2023 June 29
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Perucca E, Perucca P, White HS,
Wirrell EC
. Drug resistance in epilepsy. Lancet Neurol. 2023 Aug; 22 (8):723-734 Epub 2023 June 20
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Wirrell EC
, Riney K, Specchio N, Zuberi SM. How have the recent updated epilepsy classifications impacted on diagnosis and treatment? Expert Rev Neurother. 2023 Jul-Dec; 23 (11):969-980 Epub 2023 Sept 07
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Smith KM,
Wirrell EC
, Andrade DM, Choi H, Trenite DK, Knupp KG, Nordli DR Jr, Riva A, Stern JM, Striano P, Thiele EA, Zawar I. A comprehensive narrative review of epilepsy with eyelid myoclonia. Epilepsy Res. 2023 Jul; 193:107147 Epub 2023 Apr 26
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Smith KM, Starnes DK, Brinkmann BH, So E, Cox BC, Marsh WR, Van Gompel JJ,
Wirrell E
, Britton JW, Burkholder DB, Wong-Kisiel LC. Stereo-EEG localization of midline onset seizures on scalp EEG. Epilepsy Res. 2023 Jul; 193:107162 Epub 2023 May 05
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Buraniqi E, Guerin JB, Miller KJ, Van Gompel JJ, Krecke K,
Wirrell EC
, Nickels KC, Payne ET, Wong-Kisiel L. Temporal Encephalocele: A Treatable Etiology of Drug-Resistant Pediatric Temporal Lobe Epilepsy. Pediatr Neurol. 2023 May; 142:32-38 Epub 2022 Dec 31
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Vasquez A,
Wirrell EC
, Youssef PE. Stiripentol for the treatment of seizures associated with Dravet syndrome in patients 6 months and older and taking clobazam. Expert Rev Neurother. 2023 Apr; 23(4):297-309. Epub 2023 Mar 28.
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Agashe S, Worrell G, Britton J, Noe K, Ritaccio A,
Wirrell EC
, Nickels KC, Cascino GD, Burkholder D. Cenobamate in Generalized Epilepsy and Combined Generalized and Focal Epilepsy. Neurol Clin Pract. 2023 Apr; 13 (2):e200133 Epub 2023 Feb 15
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Nabbout R, Kuchenbuch M, Tinuper P, Cross JH,
Wirrell E
. 3D figure of epilepsy syndromes. Epilepsia Open. 2023 Mar; 8 (1):217-220 Epub 2022 Nov 10
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Nascimento FA, Friedman D, Peters JM, Bensalem-Owen MK, Cendes F, Rampp S,
Wirrell E
, Blumcke I, Tatum W, Beniczky S. Focal epilepsies: Update on diagnosis and classification. Epileptic Disord. 2023 Feb; 25 (1):1-17 Epub 2023 Apr 17
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Sullivan J,
Wirrell EC
. Dravet Syndrome as an Example of Precision Medicine in Epilepsy. Epilepsy Curr. 2023 Jan-Feb; 23 (1):4-7 Epub 2022 June 03
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Ho ML,
Wirrell EC
, Petropoulou K, Sakonju A, Chu D, Seratti G, Palasis S. Role of Electroencephalogram (EEG) and Magnetic Resonance Imaging (MRI) Findings in Early Recognition and Diagnosis of Neuronal Ceroid Lipofuscinosis Type 2 Disease. J Child Neurol. 2022 Dec; 37 (12-14):984-991 Epub 2022 Oct 03
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Sullivan J,
Wirrell E
, Knupp KG, Chen D, Zafar M, Flamini R, Stutely J, Brathwaite C, Ventola P, Avendano J, Parkerson KA, Wyant N, Ticho B. Interim results of adaptive functioning and neurodevelopment in BUTTERFLY - An observational study of children and adolescents with Dravet syndrome. Epilepsy Behav. 2022 Dec; 137 (Pt A):108955 Epub 2022 Nov 01
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Brunklaus A, Brunger T, Feng T, Fons C, Lehikoinen A, Panagiotakaki E, Vintan MA, Symonds J, Andrew J, Arzimanoglou A, Delima S, Gallois J, Hanrahan D, Lesca G, MacLeod S, Marjanovic D, McTague A, Nunez-Enamorado N, Perez-Palma E, Scott Perry M, Pysden K, Russ-Hall SJ, Scheffer IE, Sully K, Syrbe S, Vaher U, Velayutham M, Vogt J, Weiss S,
Wirrell E
, Zuberi SM, Lal D, Moller RS, Mantegazza M, Cestele S. The gain of function SCN1A disorder spectrum: novel epilepsy phenotypes and therapeutic implications. Brain. 2022 Nov 21; 145 (11):3816-3831
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Kwon CS,
Wirrell EC
, Jette N. Autism Spectrum Disorder and Epilepsy. Neurol Clin. 2022 Nov; 40 (4):831-847 Epub 2022 Sept 28
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French J, Cleary E, Dlugos D, Farfel G, Farrell K, Gidal B, Grzeskowiak CL, Gurrell R, Harden C, Stalvey TJ, Tsai J,
Wirrell EC
, Blum D, Fountain N. Considerations for determining the efficacy of new antiseizure medications in children age 1 month to younger than 2 years. Epilepsia. 2022 Oct; 63 (10):2664-2670 Epub 2022 Aug 12
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Nascimento FA, Jing J, Strowd R, Sheikh IS, Weber D, Gavvala JR, Maheshwari A, Tanner A, Ng M, Vinayan KP, Sinha SR, Yacubian EM, Rao VR, Perry MS, Fountain NB, Karakis I,
Wirrell E
, Yuan F, Friedman D, Tankisi H, Rampp S, Fasano R, Wilmshurst JM, O'Donovan C, Schomer D, Kaplan PW, Sperling MR, Benbadis S, Westover MB, Beniczky S. Competency-based EEG education: a list of "must-know" EEG findings for adult and child neurology residents. Epileptic Disord. 2022 Oct 1; 24 (5):979-982
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Buraniqi E, Dabaja H,
Wirrell EC
. Impact of Antiseizure Medications on Appetite and Weight in Children. Paediatr Drugs. 2022 Jul; 24 (4):335-363 Epub 2022 May 21
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Hood V, Berg AT, Knupp KG, Koh S, Laux L, Meskis MA, Zulfiqar-Ali Q, Perry MS, Scheffer IE, Sullivan J,
Wirrell E
, Andrade DM. COVID-19 vaccine in patients with Dravet syndrome: Observations and real-world experiences. Epilepsia. 2022 Jul; 63 (7):1778-1786 Epub 2022 Apr 20
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Baumer FM, Mytinger JR, Neville K, Briscoe Abath C, Gutierrez CA, Numis AL, Harini C, He Z, Hussain SA, Berg AT, Chu CJ, Gaillard WD, Loddenkemper T, Pasupuleti A, Samanta D, Singh RK, Singhal NS, Wusthoff CJ,
Wirrell EC
, Yozawitz E, Knupp KG, Shellhaas RA, Grinspan ZM, Pediatric Epilepsy Research Consortium//National Infantile Spasms Consortium. Inequities in Therapy for Infantile Spasms: A Call to Action. Ann Neurol. 2022 Jul; 92 (1):32-44 Epub 2022 Apr 28
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Leal-Pardinas F, Truty R, McKnight DA, Johnson B, Morales A, Bristow SL, Yar Pang T, Cohen-Pfeffer J, Izzo E, Sankar R, Koh S,
Wirrell EC
, Millichap JJ, Aradhya S. Value of genetic testing for pediatric epilepsy: Driving earlier diagnosis of ceroid lipofuscinosis type 2 Batten disease. Epilepsia. 2022 Jul; 63 (7):e68-e73 Epub 2022 May 10
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Wirrell EC
, Hood V, Knupp KG, Meskis MA, Nabbout R, Scheffer IE, Wilmshurst J, Sullivan J. International consensus on diagnosis and management of Dravet syndrome. Epilepsia. 2022 Jul; 63 (7):1761-1777 Epub 2022 May 12
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Wirrell E
, Tinuper P, Perucca E, Moshe SL. Introduction to the epilepsy syndrome papers. Epilepsia. 2022 Jun; 63 (6):1330-1332 Epub 2022 May 03
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Zuberi SM,
Wirrell E
, Yozawitz E, Wilmshurst JM, Specchio N, Riney K, Pressler R, Auvin S, Samia P, Hirsch E, Galicchio S, Triki C, Snead OC, Wiebe S, Cross JH, Tinuper P, Scheffer IE, Perucca E, Moshe SL, Nabbout R. ILAE classification and definition of epilepsy syndromes with onset in neonates and infants: Position statement by the ILAE Task Force on Nosology and Definitions. Epilepsia. 2022 Jun; 63 (6):1349-1397 Epub 2022 May 03
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Wirrell EC
, Nabbout R, Scheffer IE, Alsaadi T, Bogacz A, French JA, Hirsch E, Jain S, Kaneko S, Riney K, Samia P, Snead OC, Somerville E, Specchio N, Trinka E, Zuberi SM, Balestrini S, Wiebe S, Cross JH, Perucca E, Moshe SL, Tinuper P. Methodology for classification and definition of epilepsy syndromes with list of syndromes: Report of the ILAE Task Force on Nosology and Definitions. Epilepsia. 2022 Jun; 63 (6):1333-1348 Epub 2022 May 03
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Hirsch E, French J, Scheffer IE, Bogacz A, Alsaadi T, Sperling MR, Abdulla F, Zuberi SM, Trinka E, Specchio N, Somerville E, Samia P, Riney K, Nabbout R, Jain S, Wilmshurst JM, Auvin S, Wiebe S, Perucca E, Moshe SL, Tinuper P,
Wirrell EC
. ILAE definition of the Idiopathic Generalized Epilepsy Syndromes: Position statement by the ILAE Task Force on Nosology and Definitions. Epilepsia. 2022 Jun; 63 (6):1475-1499 Epub 2022 May 03
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Specchio N,
Wirrell EC
, Scheffer IE, Nabbout R, Riney K, Samia P, Guerreiro M, Gwer S, Zuberi SM, Wilmshurst JM, Yozawitz E, Pressler R, Hirsch E, Wiebe S, Cross HJ, Perucca E, Moshe SL, Tinuper P, Auvin S. International League Against Epilepsy classification and definition of epilepsy syndromes with onset in childhood: Position paper by the ILAE Task Force on Nosology and Definitions. Epilepsia. 2022 Jun; 63 (6):1398-1442 Epub 2022 May 03
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Riney K, Bogacz A, Somerville E, Hirsch E, Nabbout R, Scheffer IE, Zuberi SM, Alsaadi T, Jain S, French J, Specchio N, Trinka E, Wiebe S, Auvin S, Cabral-Lim L, Naidoo A, Perucca E, Moshe SL,
Wirrell EC
, Tinuper P. International League Against Epilepsy classification and definition of epilepsy syndromes with onset at a variable age: position statement by the ILAE Task Force on Nosology and Definitions. Epilepsia. 2022 Jun; 63 (6):1443-1474 Epub 2022 May 03
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Triplet EM, Nickels K, Wong-Kisiel L, Fine A,
Wirrell EC
. A tale of two cohorts: Differing outcomes in infantile-onset focal epilepsy. Epilepsia. 2022 Apr; 63 (4):950-960 Epub 2022 Feb 10
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Kerezoudis P, Gyftopoulos A, Alexander AY, Keith Starnes D, Nickels KC, Worrell GA,
Wirrell EC
, Lundstrom BN, Van Gompel JJ, Miller KJ. Safety and efficacy of responsive neurostimulation in the pediatric population: Evidence from institutional review and patient-level meta-analysis. Epilepsy Behav. 2022 Apr; 129:108646. Epub 2022 Mar 14.
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Vasquez A, Buraniqi E,
Wirrell EC
. New and emerging pharmacologic treatments for developmental and epileptic encephalopathies. Curr Opin Neurol. 2022 Apr 1; 35 (2):145-154
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Fine AL, Wong-Kisiel LC, Nickels KC,
Wirrell EC
. Masking for School-Age Children With Epilepsy: We Do Have Consensus! J Child Neurol. 2022 Feb; 37 (2):127-132 Epub 2022 Jan 05
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Cross JH, Galer BS, Gil-Nagel A, Devinsky O, Ceulemans B, Lagae L, Schoonjans AS, Donner E,
Wirrell E
, Kothare S, Agarwal A, Lock M, Gammaitoni AR. Impact of fenfluramine on the expected SUDEP mortality rates in patients with Dravet syndrome. Seizure. 2021 Dec; 93:154-159 Epub 2021 Nov 02
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Johannesen KM, Gardella E, Gjerulfsen CE, Bayat A, Rouhl RPW, Reijnders M, Whalen S, Keren B, Buratti J, Courtin T, Wierenga KJ, Isidor B, Piton A, Faivre L, Garde A, Moutton S, Tran-Mau-Them F, Denomme-Pichon AS, Coubes C, Larson A, Esser MJ, Appendino JP, Al-Hertani W, Gamboni B, Mampel A, Mayorga L, Orsini A, Bonuccelli A, Suppiej A, Van-Gils J, Vogt J, Damioli S, Giordano L, Moortgat S,
Wirrell E
, Hicks S, Kini U, Noble N, Stewart H, Asakar S, Cohen JS, Naidu SR, Collier A, Brilstra EH, Li MH, Brew C, Bigoni S, Ognibene D, Ballardini E, Ruivenkamp C, Faggioli R, Afenjar A, Rodriguez D, Bick D, Segal D, Coman D, Gunning B, Devinsky O, Demmer LA, Grebe T, Pruna D, Cursio I, Greenhalgh L, Graziano C, Singh RR, Cantalupo G, Willems M, Yoganathan S, Goes F, Leventer RJ, Colavito D, Olivotto S, Scelsa B, Andrade AV, Ratke K, Tokarz F, Khan AS, Ormieres C, Benko W, Keough K, Keros S, Hussain S, Franques A, Varsalone F, Gronborg S, Mignot C, Heron D, Nava C, Isapof A, Borlot F, Whitney R, Ronan A, Foulds N, Somorai M, Brandsema J, Helbig KL, Helbig I, Ortiz-Gonzalez XR, Dubbs H, Vitobello A, Anderson M, Spadafore D, Hunt D, Moller RS, Rubboli G, PURA study group. PURA-Related Developmental and Epileptic Encephalopathy: Phenotypic and Genotypic Spectrum. Neurol Genet. 2021 Dec; 7 (6):e613 Epub 2021 Nov 15
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Andrade DM, Berg AT, Hood V, Knupp KG, Koh S, Laux L, Meskis MA, Miller I, Perry MS, Scheffer IE, Sullivan J, Villas N,
Wirrell E
. Dravet syndrome: A quick transition guide for the adult neurologist. Epilepsy Res. 2021 Nov; 177:106743 Epub 2021 Aug 18
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Guerrini R, Balestrini S,
Wirrell EC
, Walker MC. Monogenic Epilepsies: Disease Mechanisms, Clinical Phenotypes, and Targeted Therapies. Neurology. 2021 Oct 26; 97 (17):817-831 Epub 2021 Sept 07
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Desnous B, Lenoir M, Bitton JY, Arbour M, Villeneuve N, Whiting S, Mohammed I,
Wirrell EC
, Bello-Espinosa L, Ronen GM, Lortie A, Birca A. What is the optimal duration for vigabatrin monotherapy in patients with infantile spasms: 6 months or longer? Seizure. 2021 Oct; 91:503-506 Epub 2021 Aug 02
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Grinspan ZM, Knupp KG, Patel AD, Yozawitz EG, Wusthoff CJ,
Wirrell EC
, Valencia I, Singhal NS, Nordli DR, Mytinger JR, Mitchell WG, Keator CG, Loddenkemper T, Hussain SA, Harini C, Gaillard WD, Fernandez IS, Coryell J, Chu CJ, Berg AT, Shellhaas RA. Comparative Effectiveness of Initial Treatment for Infantile Spasms in a Contemporary US Cohort. Neurology. 2021 Sep 20; 97 (12):e1217-e1228 Epub 2021 Sept 20
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Juando-Prats C, James E, Bilder DA, McNair L, Kenneally N, Helfer J, Huang N, Vila MC, Sullivan J,
Wirrell E
, Rico S. DRAVET ENGAGE. Parent caregivers of children with Dravet syndrome: Perspectives, needs, and opportunities for clinical research. Epilepsy Behav. 2021 Sep; 122:108198 Epub 2021 July 17
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Gil-Nagel A, Sullivan J, Ceulemans B,
Wirrell E
, Devinsky O, Nabbout R, Knupp KG, Scott Perry M, Polster T, Davis R, Lock M, Cortes RM, Gammaiton AR, Farfel G, Galer BS, Agarwal A. Treatment with fenfluramine in patients with Dravet syndrome has no long-term effects on weight and growth. Epilepsy Behav. 2021 Sep; 122:108212 Epub 2021 Aug 02
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Bishop KI, Isquith PK, Gioia GA, Gammaitoni AR, Farfel G, Galer BS, Nabbout R,
Wirrell EC
, Polster T, Sullivan J. Improved everyday executive functioning following profound reduction in seizure frequency with fenfluramine: Analysis from a phase 3 long-term extension study in children/young adults with Dravet syndrome. Epilepsy Behav. 2021 Aug; 121 (Pt A):108024 Epub 2021 May 20
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Augustine EF, Adams HR, de Los Reyes E, Drago K, Frazier M, Guelbert N, Laine M, Levin T, Mink JW, Nickel M, Peifer D, Schulz A, Simonati A, Topcu M, Turunen JA, Williams R,
Wirrell EC
, King S. Management of CLN1 Disease: International Clinical Consensus. Pediatr Neurol. 2021 Jul; 120:38-51 Epub 2021 Apr 09
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Bitton JY, Desnous B, Sauerwein HC, Connolly M, Weiss SK, Donner EJ, Whiting S, Mohamed IS,
Wirrell EC
, Ronen GM, Lortie A, CPEN. Cognitive outcome in children with infantile spasms using a standardized treatment protocol. A five-year longitudinal study. Seizure. 2021 Jul; 89:73-80 Epub 2021 May 11
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Payne ET,
Wirrell EC
. Discontinuing Antiseizure Medication in Neonates With Acute Symptomatic Seizures-Primum non nocere. JAMA Neurol 2021 Jul 1; 78 (7):797-799
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Privitera M, Bhathal H, Wong M, Cross JH,
Wirrell E
, Marsh ED, Mazurkiewicz-Beldzinska M, Villanueva V, Checketts D, Knappertz V, VanLandingham K. Time to onset of cannabidiol (CBD) treatment effect in Lennox-Gastaut syndrome: Analysis from two randomized controlled trials. Epilepsia. 2021 May; 62 (5):1130-1140 Epub 2021 Apr 02
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Johannessen Landmark C, Potschka H, Auvin S, Wilmshurst JM, Johannessen SI, Kasteleijn-Nolst Trenite D,
Wirrell EC
. The role of new medical treatments for the management of developmental and epileptic encephalopathies: Novel concepts and results. Epilepsia. 2021 Apr; 62 (4):857-873 Epub 2021 Feb 27
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Koh S,
Wirrell E
, Vezzani A, Nabbout R, Muscal E, Kaliakatsos M, Wickstrom R, Riviello JJ, Brunklaus A, Payne E, Valentin A, Wells E, Carpenter JL, Lee K, Lai YC, Eschbach K, Press CA, Gorman M, Stredny CM, Roche W, Mangum T. Proposal to optimize evaluation and treatment of Febrile infection-related epilepsy syndrome (FIRES): A Report from FIRES workshop. Epilepsia Open. 2021 Mar; 6 (1):62-72 Epub 2021 Jan 13
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Joshi C, Nickels K, Demarest S, Eltze C, Cross JH,
Wirrell E
. Results of an international Delphi consensus in epilepsy with myoclonic atonic seizures/ Doose syndrome. Seizure. 2021 Feb; 85:12-18 Epub 2020 Dec 28
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Alcala-Zermeno JL, Gregg NM,
Wirrell EC
, Stead M, Worrell GA, Van Gompel JJ, Lundstrom BN. Centromedian thalamic nucleus with or without anterior thalamic nucleus deep brain stimulation for epilepsy in children and adults: A retrospective case series. Seizure. 2021 Jan; 84:101-107 Epub 2020 Nov 26
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Lai YC, Muscal E, Wells E, Shukla N, Eschbach K, Hyeong Lee K, Kaliakatsos M, Desai N, Wickstrom R, Viri M, Freri E, Granata T, Nangia S, Dilena R, Brunklaus A, Wainwright MS, Gorman MP, Stredny CM, Asiri A, Hundallah K, Doja A, Payne E,
Wirrell E
, Koh S, Carpenter JL, Riviello J. Anakinra usage in febrile infection related epilepsy syndrome: an international cohort. Ann Clin Transl Neurol. 2020 Dec; 7 (12):2467-2474 Epub 2020 Dec 04
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Wirrell EC
, Grinspan ZM, Knupp KG, Jiang Y, Hammeed B, Mytinger JR, Patel AD, Nabbout R, Specchio N, Cross JH, Shellhaas RA. Care Delivery for Children With Epilepsy During the COVID-19 Pandemic: An International Survey of Clinicians. J Child Neurol. 2020 Nov; 35 (13):924-933 Epub 2020 July 15
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Kuchenbuch M, D'Onofrio G,
Wirrell E
, Jiang Y, Dupont S, Grinspan ZM, Auvin S, Wilmshurst JM, Arzimanoglou A, Cross JH, Specchio N, Nabbout R. An accelerated shift in the use of remote systems in epilepsy due to the COVID-19 pandemic. Epilepsy Behav. 2020 Nov; 112:107376 Epub 2020 Aug 31
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Wirrell EC
, Bieber ED, Vanderwiel A, Kreps S, Weaver AL. Self-injurious and suicidal behavior in young adults, teens, and children with epilepsy: A population-based study. Epilepsia. 2020 Sep; 61 (9):1919-1930 Epub 2020 July 22
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Fine A,
Wirrell EC
. Seizures in Children. Pediatr Rev. 2020 Jul; 41 (7):321-347
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Payne ET, Koh S,
Wirrell EC
. Extinguishing Febrile Infection-Related Epilepsy Syndrome: Pipe Dream or Reality? Semin Neurol. 2020 Apr; 40 (2):263-272 Epub 2020 Mar 17
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Nabbout R, Mistry A, Zuberi S, Villeneuve N, Gil-Nagel A, Sanchez-Carpintero R, Stephani U, Laux L,
Wirrell E
, Knupp K, Chiron C, Farfel G, Galer BS, Morrison G, Lock M, Agarwal A, Auvin S, FAiRE, DS Study Group. Fenfluramine for Treatment-Resistant Seizures in Patients With Dravet Syndrome Receiving Stiripentol-Inclusive Regimens: A Randomized Clinical Trial. JAMA Neurol. 2020 Mar 1; 77 (3):300-308
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Kerezoudis P,
Wirrell E
, Miller K. Post-placement Lead Deformation Secondary to Cerebrospinal Fluid Loss in Transventricular Trajectory During Responsive Neurostimulation Surgery. Cureus. 2020 Jan 30; 12 (1):e6823
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Wallace A,
Wirrell E
, Payne E. Seizure Rescue Medication Use among US Pediatric Epilepsy Providers: A Survey of the Pediatric Epilepsy Research Consortium. J Pediatr. 2019 Sep; 212:111-116 Epub 2019 June 14
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Lukmanji S, Manji SA, Kadhim S, Sauro KM,
Wirrell EC
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