Michael H. Silber, M.B., Ch.B.

  1. Neurologist
  2. Pulmonologist
  1. Alexandres CA, McCarter SJ, Tabatabai GM, LeClair-Visonneau L, Feemster JC, Gossard TR, Strainis EP, Jagielski JT, Kelleher MR, Finstuen T, Ali F, Botha H, Graff-Radford J, Olson EJ, Sandness DJ, Morgenthaler TJ, Kantarci K, Savica R, Singer W, Covassin N, Somers VK, Kirkland JL, Junna M, Lipford M, Matarese CA, Moore JL, Tippmann-Peikert M, Carvalho DZ, Boeve BF, Silber MH, St Louis EK. Phenoconversion in Women and Men With Isolated REM Sleep Behavior Disorder: A Retrospective Cohort Study. Neurology. 2024 Nov 26; 103 (10):e209993 Epub 2024 Oct 25
    View PubMed
  2. Silber MH, Block DR, Louis EKS. Serum ferritin measurements differ according to assay used: implications for iron therapy in restless legs syndrome. J Clin Sleep Med. 2024 Aug 22 [Epub ahead of print]
    View PubMed
  3. Leclair-Visonneau L, Feemster JC, Bibi N, Gossard TR, Jagielski JT, Strainis EP, Carvalho DZ, Timm PC, Bliwise DL, Boeve BF, Silber MH, McCarter SJ, St Louis EK. Contemporary diagnostic visual and automated polysomnographic REM sleep without atonia thresholds in isolated REM sleep behavior disorder. J Clin Sleep Med. 2024 Feb 1; 20 (2):279-291
    View PubMed
  4. Pagani-Estevez GL, Holland MT, Tippmann-Peikert M, Benarroch EE, Silber MH, Carvalho DZ. Potential therapeutic benefit of spinal cord stimulation in restless legs syndrome: scoping review and mechanistic considerations. Pain Med. 2023 Oct 13; 24 (Supplement_2):S18-S23
    View PubMed
  5. Gossard TR, Teigen LN, Yoo S, Timm PC, Jagielski J, Bibi N, Feemster JC, Steele T, Carvalho DZ, Junna MR, Lipford MC, Tippmann Peikert M, LeClair-Visonneau L, McCarter SJ, Boeve BF, Silber MH, Hirsch J, Sharp RR, St Louis EK. Patient values and preferences regarding prognostic counseling in isolated REM sleep behavior disorder. Sleep. 2023 Jan 11; 46 (1)
    View PubMed
  6. Covassin N, Lu D, St Louis EK, Chahal AA, Schulte PJ, Mansukhani MP, Xie J, Lipford MC, Li N, Ramar K, Caples SM, Gay PC, Olson EJ, Silber MH, Li J, Somers VK. Sex-specific associations between daytime sleepiness, chronic diseases and mortality in obstructive sleep apnea. Front Neurosci. 2023; 17:1210206 Epub 2023 June 23
    View PubMed
  7. McCarter SJ, Coon EA, Benarroch EE, Silber MH, St Louis EK. Nocturnal Pulse Event Frequency Is Reduced in Multiple System Atrophy. Ann Neurol. 2023 Jan; 93 (1):205-212 Epub 2022 Nov 02
    View PubMed
  8. Gali B, Silber MH, Hanson AC, Portner E, Gay P. Perioperative outcomes of patients with restless legs syndrome: a single-center retrospective review. J Clin Sleep Med. 2022 Jul 1; 18 (7):1841-1846
    View PubMed
  9. Sandness DJ, McCarter SJ, Dueffert LG, Shepard PW, Enke AM, Fields J, Mielke MM, Boeve BF, Silber MH, St Louis EK. Cognition and driving ability in isolated and symptomatic REM sleep behavior disorder. Sleep. 2022 Apr 11; 45 (4)
    View PubMed
  10. Sandness DJ, McCarter SJ, Dueffert LG, Shepard PW, Enke AM, Fields J, Mielke MM, Boeve BF, Silber MH, St Louis EK. Cognition and driving ability in isolated and symptomatic REM sleep behavior disorder. Sleep. 2022 Apr 11; 45 (4)
    View PubMed
  11. Feemster JC, Steele TA, Palermo KP, Ralston CL, Tao Y, Bauer DA, Edgar L, Rivera S, Walters-Smith M, Gossard TR, Teigen LN, Timm PC, Richardson JW, Auger RR, Kolla B, McCarter SJ, Boeve BF, Silber MH, St Louis EK. Abnormal rapid eye movement sleep atonia control in chronic post-traumatic stress disorder. Sleep. 2022 Mar 14; 45 (3)
    View PubMed
  12. Devine MF, Feemster JC, Lieske EA, McCarter SJ, Sandness DJ, Steele T, Timm PC, Mandrekar J, Boeve BF, Silber MH, Dubey D, McKeon A, St Louis EK. Objective sleep profile in LGI1/CASPR2 autoimmunity. Sleep. 2022 Feb 14; 45 (2)
    View PubMed
  13. Silber MH, Buchfuhrer MJ, Earley CJ, Koo BB, Manconi M, Winkelman JW, Scientific and Medical Advisory Board of the Restless Legs Syndrome Foundation. The Management of Restless Legs Syndrome: An Updated Algorithm. Mayo Clin Proc. 2021 Jul; 96 (7):1921-1937
    View PubMed
  14. Gandhi KD, Mansukhani MP, Silber MH, Kolla BP. Excessive Daytime Sleepiness: A Clinical Review. Mayo Clin Proc. 2021 May; 96 (5):1288-1301 Epub 2021 Apr 09
    View PubMed
  15. Teigen LN, Sharp RR, Hirsch JR, Campbell E, Timm PC, Sandness DJ, Feemster JC, Gossard TR, Faber SM, Steele TA, Rivera S, Junna MR, Lipford MC, Tippmann-Peikert M, Kotagal S, Ju YE, Howell M, Schenck CH, Videnovic A, Jennum P, Hogl B, Stefani A, Arnulf I, Heidbreder A, Lewis S, McCarter SJ, Boeve BF, Silber MH, St Louis EK. Specialist approaches to prognostic counseling in isolated REM sleep behavior disorder. Sleep Med. 2021 Mar; 79:107-112 Epub 2020 Dec 24
    View PubMed
  16. Gossard TR, McCarter SJ, Gorres E, Feemster JC, Timm PC, Teigen LN, Ralston CL, Westerland SM, Conway JP, Jagielski JT, Olson CD, Edgar LJ, Veum EL, Savica R, Boeve BF, Silber MH, St Louis EK. Quantitative REM Sleep without Atonia in Parkinson's Disease and Essential Tremor. Mov Disord Clin Pract. 2021 Jan; 8 (1):37-43 Epub 2020 Nov 26
    View PubMed
  17. Kolla BP, Jahani Kondori M, Silber MH, Samman H, Dhankikar S, Mansukhani MP. Advance taper of antidepressants prior to multiple sleep latency testing increases the number of sleep-onset rapid eye movement periods and reduces mean sleep latency. J Clin Sleep Med. 2020 Nov 15; 16 (11):1921-1927
    View PubMed
  18. Silber MH. Parasomnias occurring in non-rapid eye movement sleep Continuum (Minneap Minn). 2020; 26(4).
  19. McCarter SJ, Gehrking TL, St Louis EK, Suarez MD, Boeve BF, Silber MH, Low PA, Singer W. Autonomic dysfunction and phenoconversion in idiopathic REM sleep behavior disorder. Clin Auton Res. 2020 Jun; 30 (3):207-213 Epub 2020 Mar 19
    View PubMed
  20. McCarter SJ, Tabatabai GM, Jong HY, Sandness DJ, Timm PC, Johnson KL, McCarter AR, Savica R, Vemuri P, Machulda MM, Kantarci K, Mielke MM, Boeve BF, Silber MH, St Louis EK. REM sleep atonia loss distinguishes synucleinopathy in older adults with cognitive impairment. Neurology. 2020 Jan 7; 94 (1):e15-e29 Epub 2019 Dec 12
    View PubMed
  21. McCarter SJ, Feemster JC, Tabatabai GM, Sandness DJ, Timm PC, McCarter AR, Talley HN, Junna MR, Savica R, Singer W, Coon EA, Benarroch EE, Josephs KA, Boeve BF, Silber MH, St Louis EK. Submentalis Rapid Eye Movement Sleep Muscle Activity: A Potential Biomarker for Synucleinopathy. Ann Neurol. 2019 Dec; 86 (6):969-974
    View PubMed
  22. Feemster JC, Jung Y, Timm PC, Westerland SM, Gossard TR, Teigen LN, Buchal LA, Cattaneo EFD, Imlach CA, Mccarter SJ, Smith KL, Boeve BF, Silber MH, St Louis EK. Normative and isolated rapid eye movement sleep without atonia in adults without REM sleep behavior disorder. Sleep. 2019 Oct 9; 42 (10)
    View PubMed
  23. Feinstein MA, Sharp RR, Sandness DJ, Feemster JC, Junna M, Kotagal S, Lipford MC, Tippmann-Peikert M, Boeve BF, Silber MH, St Louis EK. Physician and patient determinants of prognostic counseling in idiopathic REM sleep-behavior disorder. Sleep Med. 2019 Oct; 62:80-85 Epub 2019 Mar 22
    View PubMed
  24. McCarter SJ, Sandness DJ, McCarter AR, Feemster JC, Teigen LN, Timm PC, Boeve BF, Silber MH, St Louis EK. REM sleep muscle activity in idiopathic REM sleep behavior disorder predicts phenoconversion. Neurology. 2019 Sep 17; 93 (12):e1171-e1179 Epub 2019 Aug 16
    View PubMed
  25. McCarter SJ, Boeve BF, Graff-Radford NR, Silber MH, St Louis EK. Neuroprotection in idiopathic REM sleep behavior disorder: a role for exercise? Sleep 2019 Jun 11; 42 (6)
    View PubMed
  26. Boeve A, Ferman TJ, Aakre J, St Louis E, Silber M, Machulda M, Fields J, Graff-Radford N, Mielke M, Geda Y, Jones D, Graff-Radford J, Knopman D, Petersen R, Boeve B. Excessive Daytime Sleepiness in Major Dementia Syndromes. Am J Alzheimers Dis Other Demen. 2019 Jun; 34 (4):261-264 Epub 2019 Feb 10
    View PubMed
  27. Kolla BP, Mansukhani MP, Olson EJ, St Louis EK, Silber MH, Morgenthaler TI. Medical Cannabis for Obstructive Sleep Apnea: Premature and Potentially Harmful. Mayo Clin Proc. 2018 Jun; 93 (6):689-692
    View PubMed
  28. Coon EA, Ahlskog JE, Silber MH, Fealey RD, Benarroch EE, Sandroni P, Mandrekar JN, Low PA, Singer W. Do selective serotonin reuptake inhibitors improve survival in multiple system atrophy? Parkinsonism Relat Disord. 2018 Mar; 48:51-53 Epub 2017 Dec 14
    View PubMed
  29. Cohen A, Mandrekar J, St Louis EK, Silber MH, Kotagal S. Comorbidities in a community sample of narcolepsy. Sleep Med. 2018 Mar; 43:14-18 Epub 2017 Nov 21
    View PubMed
  30. Jung Y, Jordan LG 3rd, Lowe VJ, Kantarci K, Parisi JE, Dickson DW, Murray ME, Reichard RR, Ferman TJ, Jones DT, Graff-Radford J, Savica R, Machulda MM, Fields JA, Allen LA, Drubach DA, St Louis EK, Silber MH, Jack CR Jr, Knopman DS, Petersen RC, Boeve BF. Clinicopathological and (123)I-FP-CIT SPECT correlations in patients with dementia. Ann Clin Transl Neurol. 2018 Mar; 5 (3):376-381 Epub 2018 Jan 24
    View PubMed
  31. Silber MH, Becker PM, Buchfuhrer MJ, Earley CJ, Ondo WG, Walters AS, Winkelman JW, Scientific and Medical Advisory Board, Restless Legs Syndrome Foundation. The Appropriate Use of Opioids in the Treatment of Refractory Restless Legs Syndrome. Mayo Clin Proc. 2018 Jan; 93 (1):59-67
    View PubMed
  32. Silber MH. Diagnostic approach and investigation in sleep medicine CONTINUUM: Lifelong Learning in Neurology. 2017 Aug; 23 (4):973-88
  33. Iranzo A, Silber MH. Stop, look, and listen: Sleep in movement disorders. Mov Disord 2017 May; 32 (5):633-635 Epub 2017 Apr 24
    View PubMed
  34. McCarter SJ, St Louis EK, Sandness DJ, Duwell EJ, Timm PC, Boeve BF, Silber MH. Diagnostic REM sleep muscle activity thresholds in patients with idiopathic REM sleep behavior disorder with and without obstructive sleep apnea. Sleep Med. 2017 May; 33:23-29 Epub 2016 May 11
    View PubMed
  35. Jung Y, Boot BP, Mielke MM, Ferman TJ, Geda YE, McDade E, Christianson TJH, Knopman DS, St Louis EK, Silber MH, Petersen RC, Boeve BF. Phenoconversion from probable rapid eye movement sleep behavior disorder to mild cognitive impairment to dementia in a population-based sample. Alzheimers Dement (Amst). 2017; 8:127-130 Epub 2017 May 30
    View PubMed
  36. Mantyh WG, Auger RR, Morgenthaler TI, Silber MH, Moore WR. Examining the Frequency of Stimulant Misuse among Patients with Primary Disorders of Hypersomnolence: A Retrospective Cohort Study. J Clin Sleep Med. 2016 May 15; 12 (5):659-62
    View PubMed
  37. Garcia-Borreguero D, Silber MH, Winkelman JW, Hogl B, Bainbridge J, Buchfuhrer M, Hadjigeorgiou G, Inoue Y, Manconi M, Oertel W, Ondo W, Winkelmann J, Allen RP. Guidelines for the first-line treatment of restless legs syndrome/Willis-Ekbom disease, prevention and treatment of dopaminergic augmentation: a combined task force of the IRLSSG, EURLSSG, and the RLS-foundation. Sleep Med. 2016 May; 21:1-11 Epub 2016 Feb 23
    View PubMed
  38. St Louis EK, Duwell EJ, Orbelo DM, Benarroch EE, Coon EA, Boeve BF, Silber MH. A 76 Year-Old Woman with Sleep and Waking Stridor, Sleep Talking, Orthostatic Hypotension, and Imbalance. J Clin Sleep Med. 2016 Jan; 12 (1):143-5
    View PubMed
  39. Silber MH. Autoimmune sleep disorders. Handb Clin Neurol. 2016; 133:317-26.
    View PubMed
  40. Peterson MKT, Gruhlke RC, Sims RC, Wright-Peterson VM, Karon BS, Tynsky TA, Lammers DL, Bender CE, Silber MH, Krom BA, Lessard MS. Blended learning: transformation of phlebotomy education at Mayo Clinic Clinical Laboratory Science. 2016; 29(4):219-26. Epub 1900 Jan 01.
  41. McCarter SJ, Tippmann-Peikert M, Sandness DJ, Flanagan EP, Kantarci K, Boeve BF, Silber MH, St Louis EK. Neuroimaging-evident lesional pathology associated with REM sleep behavior disorder. Sleep Med. 2015 Dec; 16: (12)1502-10.
    View PubMed
  42. Coon EA, Sletten DM, Suarez MD, Mandrekar JN, Ahlskog JE, Bower JH, Matsumoto JY, Silber MH, Benarroch EE, Fealey RD, Sandroni P, Low PA, Singer W. Clinical features and autonomic testing predict survival in multiple system atrophy. Brain. 2015 Dec; 138(Pt 12):3623-31. Epub 2015 Sep 13.
    View PubMed
  43. McCarter SJ, St Louis EK, Sandness DJ, Arndt K, Erickson M, Tabatabai G, Boeve BF, Silber MH. Antidepressants Increase REM Sleep Muscle Tone in Patients with and without REM Sleep Behavior Disorder. Sleep. 2015 Jun 1; 38 (6):907-17 Epub 2015 June 01
    View PubMed
  44. St Louis EK, McCarter SJ, Boeve BF, Silber MH, Kantarci K, Benarroch EE, Rando A, Tippmann-Peikert M, Olson EJ, Mauermann ML. Lesional REM sleep behavior disorder localizes to the dorsomedial pons. Neurology. 2014 Nov 11; 83 (20):1871-3 Epub 2014 Oct 10
    View PubMed
  45. McCarter SJ, St Louis EK, Boswell CL, Dueffert LG, Slocumb N, Boeve BF, Silber MH, Olson EJ, Morgenthaler TI, Tippmann-Peikert M. Factors associated with injury in REM sleep behavior disorder. Sleep Med. 2014 Nov; 15 (11):1332-8 Epub 2014 June 23
    View PubMed
  46. McCarter SJ, St Louis EK, Duwell EJ, Timm PC, Sandness DJ, Boeve BF, Silber MH. Diagnostic thresholds for quantitative REM sleep phasic burst duration, phasic and tonic muscle activity, and REM atonia index in REM sleep behavior disorder with and without comorbid obstructive sleep apnea. Sleep. 2014 Oct 1; 37 (10):1649-62 Epub 2014 Oct 01
    View PubMed
  47. McCarter SJ, St Louis EK, Boeve BF, Sandness DJ, Silber MH. Greatest rapid eye movement sleep atonia loss in men and older age. Ann Clin Transl Neurol. 2014 Sep; 1 (9):733-8 Epub 2014 Sept 02
    View PubMed
  48. Bancos I, Nannenga MR, Bostwick JM, Silber MH, Erickson D, Nippoldt TB. Impulse control disorders in patients with dopamine agonist-treated prolactinomas and nonfunctioning pituitary adenomas: a case-control study. Clin Endocrinol (Oxf). 2014 Jun; 80 (6):863-8 Epub 2013 Dec 16
    View PubMed
  49. Ferman TJ, Smith GE, Dickson DW, Graff-Radford NR, Lin SC, Wszolek Z, Van Gerpen JA, Uitti R, Knopman DS, Petersen RC, Parisi JE, Silber MH, Boeve BF. Abnormal daytime sleepiness in dementia with Lewy bodies compared to Alzheimer's disease using the Multiple Sleep Latency Test. Alzheimers Res Ther. 2014; 6 (9):76 Epub 2014 Dec 10
    View PubMed
  50. St Louis EK, Jinnur P, McCarter SJ, Duwell EJ, Benarroch EE, Kantarci K, Pichelmann MA, Silber MH, Boeve BF, Olson EJ, Morgenthaler TI, Somers VK. Chiari 1 Malformation Presenting as Central Sleep Apnea during Pregnancy: A Case Report, Treatment Considerations, and Review of the Literature. Front Neurol. 2014; 5:195 Epub 2014 Oct 24
    View PubMed
  51. Murray ME, Ferman TJ, Boeve BF, Przybelski SA, Lesnick TG, Liesinger AM, Senjem ML, Gunter JL, Preboske GM, Lowe VJ, Vemuri P, Dugger BN, Knopman DS, Smith GE, Parisi JE, Silber MH, Graff-Radford NR, Petersen RC, Jack CR Jr, Dickson DW, Kantarci K. MRI and pathology of REM sleep behavior disorder in dementia with Lewy bodies. Neurology. 2013 Nov 5; 81 (19):1681-9 Epub 2013 Oct 09
    View PubMed
  52. Chopra A, Selim B, Silber MH, Krahn L. Para-suicidal amnestic behavior associated with chronic zolpidem use: implications for patient safety. Psychosomatics. 2013 Sep-Oct; 54 (5):498-501 Epub 2013 Jan 22
    View PubMed
  53. Silber MH, Becker PM, Earley C, Garcia-Borreguero D, Ondo WG, Medical Advisory Board of the Willis-Ekbom Disease Foundation. Willis-Ekbom Disease Foundation revised consensus statement on the management of restless legs syndrome. Mayo Clin Proc. 2013 Sep; 88(9):977-86.
    View PubMed
  54. Boeve BF, Silber MH, Ferman TJ, Lin SC, Benarroch EE, Schmeichel AM, Ahlskog JE, Caselli RJ, Jacobson S, Sabbagh M, Adler C, Woodruff B, Beach TG, Iranzo A, Gelpi E, Santamaria J, Tolosa E, Singer C, Mash DC, Luca C, Arnulf I, Duyckaerts C, Schenck CH, Mahowald MW, Dauvilliers Y, Graff-Radford NR, Wszolek ZK, Parisi JE, Dugger B, Murray ME, Dickson DW. Clinicopathologic correlations in 172 cases of rapid eye movement sleep behavior disorder with or without a coexisting neurologic disorder. Sleep Med. 2013 Aug; 14 (8):754-62 Epub 2013 Mar 07
    View PubMed
  55. Lam EM, Shepard PW, St Louis EK, Dueffert LG, Slocumb N, McCarter SJ, Silber MH, Boeve BF, Olson EJ, Somers VK, Milone M. Restless legs syndrome and daytime sleepiness are prominent in myotonic dystrophy type 2. Neurology. 2013 Jul 9; 81 (2):157-64 Epub 2013 June 07
    View PubMed
  56. Garcia-Borreguero D, Kohnen R, Silber MH, Winkelman JW, Earley CJ, Hogl B, Manconi M, Montplaisir J, Inoue Y, Allen RP. The long-term treatment of restless legs syndrome/Willis-Ekbom disease: evidence-based guidelines and clinical consensus best practice guidance: a report from the International Restless Legs Syndrome Study Group. Sleep Med. 2013 Jul; 14(7):675-84.
    View PubMed
  57. Boeve BF, Molano JR, Ferman TJ, Lin SC, Bieniek K, Tippmann-Peikert M, Boot B, St Louis EK, Knopman DS, Petersen RC, Silber MH. Validation of the Mayo Sleep Questionnaire to screen for REM sleep behavior disorder in a community-based sample. J Clin Sleep Med. 2013 May 15; 9 (5):475-80
    View PubMed
  58. Avidan AY, Vaughn BV, Silber MH. The current state of sleep medicine education in US neurology residency training programs: where do we go from here? J Clin Sleep Med. 2013 Mar 15; 9(3):281-6.
    View PubMed
  59. McCarter SJ, Boswell CL, St Louis EK, Dueffert LG, Slocumb N, Boeve BF, Silber MH, Olson EJ, Tippmann-Peikert M. Treatment outcomes in REM sleep behavior disorder. Sleep Med. 2013 Mar; 14 (3):237-42 Epub 2013 Jan 23
    View PubMed
  60. Silber MH. Sleep-related movement disorders. Continuum (Minneap Minn). 2013 Feb; 19(1 Sleep Disorders):170-84.
    View PubMed
  61. Flanagan EP, Gavrilova RH, Boeve BF, Kumar N, Jelsing EJ, Silber MH. Adult-onset autosomal dominant leukodystrophy presenting with REM sleep behavior disorder. Neurology. 2013 Jan 1; 80(1):118-20. Epub 2012 Dec 12.
    View PubMed
  62. Pao WC, Boeve BF, Ferman TJ, Lin SC, Smith GE, Knopman DS, Graff-Radford NR, Petersen RC, Parisi JE, Dickson DW, Silber MH. Polysomnographic findings in dementia with Lewy bodies. Neurologist. 2013 Jan; 19 (1):1-6
    View PubMed
  63. Auger RR, Varghese R, Silber MH, Slocumb NL. Total sleep time obtained from actigraphy versus sleep logs in an academic sleep center and impact on further sleep testing. Nat Sci Sleep. 2013; 5:125-31. Epub 2013 Oct 03.
    View PubMed
  64. Lipford MC, Silber MH. Long-term use of pramipexole in the management of restless legs syndrome. Sleep Med. 2012 Dec; 13 (10):1280-5 Epub 2012 Oct 01
    View PubMed
  65. Andlauer O, Moore H, Hong SC, Dauvilliers Y, Kanbayashi T, Nishino S, Han F, Silber MH, Rico T, Einen M, Kornum BR, Jennum P, Knudsen S, Nevsimalova S, Poli F, Plazzi G, Mignot E. Predictors of hypocretin (orexin) deficiency in narcolepsy without cataplexy. Sleep. 2012 Sep; 35(9):1247-55F. Epub 2012 Sep 01.
    View PubMed
  66. Quan SF, Buysse DJ, Ward SL, Harding SM, Iber C, Kapur VK, Rowley JA, Sateia MJ, Silber MH, Sorscher AJ, Vaughn BV, Witmans M, Woodson BT, Zee P, Mills LE, Hess BJ. Development and growth of a large multispecialty certification examination: sleep medicine certification--results of the first three examinations. J Clin Sleep Med. 2012 Apr 15; 8(2):221-4.
    View PubMed
  67. Silber MH. Staging sleep. Sleep Med. Clin. 2012; 7(3):487-96.
  68. Boot BP, Boeve BF, Roberts RO, Ferman TJ, Geda YE, Pankratz VS, Ivnik RJ, Smith GE, McDade E, Christianson TJ, Knopman DS, Tangalos EG, Silber MH, Petersen RC. Probable rapid eye movement sleep behavior disorder increases risk for mild cognitive impairment and Parkinson disease: a population-based study. Ann Neurol. 2012 Jan; 71 (1):49-56
    View PubMed
  69. Ferman TJ, Boeve BF, Smith GE, Lin SC, Silber MH, Pedraza O, Wszolek Z, Graff-Radford NR, Uitti R, Van Gerpen J, Pao W, Knopman D, Pankratz VS, Kantarci K, Boot B, Parisi JE, Dugger BN, Fujishiro H, Petersen RC, Dickson DW. Inclusion of RBD improves the diagnostic classification of dementia with Lewy bodies. Neurology. 2011 Aug 30; 77 (9):875-82 Epub 2011 Aug 17
    View PubMed
  70. Cornelius JR, Pittock SJ, McKeon A, Lennon VA, Aston PA, Josephs KA, Tippmann-Peikert M, Silber MH. Sleep manifestations of voltage-gated potassium channel complex autoimmunity. Arch Neurol. 2011 Jun; 68 (6):733-8
    View PubMed
  71. Boeve BF, Molano JR, Ferman TJ, Smith GE, Lin SC, Bieniek K, Haidar W, Tippmann-Peikert M, Knopman DS, Graff-Radford NR, Lucas JA, Petersen RC, Silber MH. Validation of the Mayo Sleep Questionnaire to screen for REM sleep behavior disorder in an aging and dementia cohort. Sleep Med. 2011 May; 12 (5):445-53 Epub 2011 Feb 23
    View PubMed
  72. Adams C, McKeon A, Silber MH, Kumar R. Narcolepsy, REM sleep behavior disorder, and supranuclear gaze palsy associated with Ma1 and Ma2 antibodies and tonsillar carcinoma. Arch Neurol. 2011 Apr; 68(4):521-4.
    View PubMed
  73. Earley CJ, Silber MH. Restless legs syndrome: understanding its consequences and the need for better treatment. Sleep Med. 2010 Oct; 11(9):807-15.
    View PubMed
  74. Claassen DO, Josephs KA, Ahlskog JE, Silber MH, Tippmann-Peikert M, Boeve BF. REM sleep behavior disorder preceding other aspects of synucleinopathies by up to half a century. Neurology. 2010 Aug 10; 75 (6):494-9 Epub 2010 July 28
    View PubMed
  75. Molano J, Boeve B, Ferman T, Smith G, Parisi J, Dickson D, Knopman D, Graff-Radford N, Geda Y, Lucas J, Kantarci K, Shiung M, Jack C, Silber M, Pankratz VS, Petersen R. Mild cognitive impairment associated with limbic and neocortical Lewy body disease: a clinicopathological study. Brain. 2010 Feb; 133 (Pt 2):540-56 Epub 2009 Nov 04
    View PubMed
  76. Cornelius JR, Tippmann-Peikert M, Slocumb NL, Frerichs CF, Silber MH. Impulse control disorders with the use of dopaminergic agents in restless legs syndrome: a case-control study. Sleep. 2010 Jan; 33 (1):81-7
    View PubMed
  77. Kuzniar TJ, Morgenthaler TI, Prakash UB, Pallanch JF, Silber MH, Tippmann-Peikert M. Effects of continuous positive airway pressure on stridor in multiple system atrophy-sleep laryngoscopy. J Clin Sleep Med. 2009 Feb 15; 5 (1):65-7
    View PubMed
  78. Silber MH. Staging sleep. Sleep Med. Clin. 2009; 4(3):343-52.
  79. Teman PT, Tippmann-Peikert M, Silber MH, Slocumb NL, Auger RR. Idiopathic rapid-eye-movement sleep disorder: associations with antidepressants, psychiatric diagnoses, and other factors, in relation to age of onset. Sleep Med. 2009 Jan; 10(1):60-5. Epub 2008 Jan 28.
    View PubMed
  80. Boeve BF, Silber MH, Saper CB, Ferman TJ, Dickson DW, Parisi JE, Benarroch EE, Ahlskog JE, Smith GE, Caselli RC, Tippman-Peikert M, Olson EJ, Lin SC, Young T, Wszolek Z, Schenck CH, Mahowald MW, Castillo PR, Del Tredici K, Braak H. Pathophysiology of REM sleep behaviour disorder and relevance to neurodegenerative disease. Brain. 2007 Nov; 130(Pt 11):2770-88. Epub 2007 Apr 05.
    View PubMed
  81. Hauri PJ, Silber MH, Boeve BF. The treatment of parasomnias with hypnosis: a 5-year follow-up study. J Clin Sleep Med. 2007 Jun 15; 3 (4):369-73
    View PubMed
  82. Silber MH, Ancoli-Israel S, Bonnet MH, Chokroverty S, Grigg-Damberger MM, Hirshkowitz M, Kapen S, Keenan SA, Kryger MH, Penzel T, Pressman MR, Iber C. The visual scoring of sleep in adults. J Clin Sleep Med. 2007 Mar 15; 3 (2):121-31
    View PubMed
  83. Kuzniar TJ, Silber MH. Multiple skeletal injuries resulting from uncontrolled restless legs syndrome. J Clin Sleep Med. 2007 Feb 15; 3(1):60-1.
    View PubMed
  84. Moore WR, Silber MH, Decker PA, Heim-Penokie PC, Sikkink VK, Slocumb N, Richardson JW, Krahn LE. Cataplexy Emotional Trigger Questionnaire (CETQ)--a brief patient screen to identify cataplexy in patients with narcolepsy. J Clin Sleep Med. 2007 Feb 15; 3 (1):37-40
    View PubMed
  85. Tippmann-Peikert M, Park JG, Boeve BF, Shepard JW, Silber MH. Pathologic gambling in patients with restless legs syndrome treated with dopaminergic agonists. Neurology. 2007 Jan 23; 68(4):301-3.
    View PubMed
  86. Silber MH. Insomnia. CONTINUUM Lifelong Learn. Neurol. 2007; 13(3 SLEEP DISORDERS):85-100.
  87. Penzel T, Hirshkowitz M, Harsh J, Chervin RD, Butkov N, Kryger M, Malow B, Vitiello MV, Silber MH, Kushida CA, Chesson Jr AL. Digital analysis and technical specifications. J Clin Sleep Med. 2007; 3(2):109-20.
  88. Boeve BF, Dickson DW, Olson EJ, Shepard JW, Silber MH, Ferman TJ, Ahlskog JE, Benarroch EE. Insights into REM sleep behavior disorder pathophysiology in brainstem-predominant Lewy body disease. Sleep Med. 2007 Jan; 8 (1):60-4 Epub 2006 Dec 06
    View PubMed
  89. Young TJ, Silber MH. Hypersomnias of central origin. Chest. 2006 Sep; 130(3):913-20.
    View PubMed
  90. Silber MH. The investigation of sleepiness. Sleep Medicine Clinics. 2006 Mar; 1(1):1-7.
  91. Morgenthaler TI, Olson EJ, Gay P, Decker PA, Herold D, Moore W, Silber MH, Krahn L. Effect of a targeted obstructive sleep apnea consult to improve access and quality at a sleep disorders center. J Clin Sleep Med. 2006 Jan 15; 2(1):49-56.
    View PubMed
  92. Krahn LE, Lymp JF, Moore WR, Slocumb N, Silber MH. Characterizing the emotions that trigger cataplexy. J Neuropsychiatry Clin Neurosci. 2005 Winter; 17(1):45-50.
    View PubMed
  93. Black JL 3rd, Silber MH, Krahn LE, Avula RK, Walker DL, Pankratz VS, Fredrickson PA, Slocumb NL. Studies of humoral immunity to preprohypocretin in human leukocyte antigen DQB1*0602-positive narcoleptic subjects with cataplexy. Biol Psychiatry. 2005 Sep 15; 58(6):504-9.
    View PubMed
  94. Silber MH. Clinical practice. Chronic insomnia. N Engl J Med. 2005 Aug 25; 353 (8):803-10
    View PubMed
  95. Silber MH, Hansen MR, Girish M. Complex nocturnal visual hallucinations. Sleep Med. 2005 Jul; 6(4):363-6.
    View PubMed
  96. Auger RR, Goodman SH, Silber MH, Krahn LE, Pankratz VS, Slocumb NL. Risks of high-dose stimulants in the treatment of disorders of excessive somnolence: a case-control study. Sleep. 2005 Jun; 28 (6):667-72
    View PubMed
  97. Black JL 3rd, Silber MH, Krahn LE, Fredrickson PA, Pankratz VS, Avula R, Walker DL, Slocumb NL. Analysis of hypocretin (orexin) antibodies in patients with narcolepsy. Sleep. 2005 Apr; 28 (4):427-31
    View PubMed
  98. Shepard JW Jr, Buysse DJ, Chesson AL Jr, Dement WC, Goldberg R, Guilleminault C, Harris CD, Iber C, Mignot E, Mitler MM, Moore KE, Phillips BA, Quan SF, Rosenberg RS, Roth T, Schmidt HS, Silber MH, Walsh JK, White DP. History of the development of sleep medicine in the United States. J Clin Sleep Med. 2005 Jan 15; 1 (1):61-82
    View PubMed
  99. Silber MH. Chapter 28 Headaches and sleep disorders. Handbook of Clinical Neurophysiology. 2005; 6(C):337-42.
  100. Kotagal S, Silber MH. Childhood-onset restless legs syndrome. Ann Neurol. 2004 Dec; 56(6):803-7.
    View PubMed
  101. Josephs KA, Silber MH, Fealey RD, Nippoldt TB, Auger RG, Vernino S. Neurophysiologic studies in Morvan syndrome. J Clin Neurophysiol. 2004 Nov-Dec; 21 (6):440-5
    View PubMed
  102. Boeve BF, Silber MH, Ferman TJ. REM sleep behavior disorder in Parkinson's disease and dementia with Lewy bodies. J Geriatr Psychiatry Neurol. 2004 Sep; 17(3):146-57.
    View PubMed
  103. Silber MH, Ehrenberg BL, Allen RP, Buchfuhrer MJ, Earley CJ, Hening WA, Rye DB, Medical Advisory Board of the Restless Legs Syndrome Foundation. An algorithm for the management of restless legs syndrome. Mayo Clin Proc. 2004 Jul; 79 (7):916-22
    View PubMed
  104. Hening WA, Allen RP, Earley CJ, Picchietti DL, Silber MH. An update on the dopaminergic treatment of restless legs syndrome and periodic limb movement disorder. Sleep. 2004 May 1; 27(3):560-83.
    View PubMed
  105. Silber MH, Girish M, Izurieta R. Pramipexole in the management of restless legs syndrome: an extended study. Sleep. 2003 Nov 1; 26 (7):819-21
    View PubMed
  106. Boeve BF, Silber MH, Parisi JE, Dickson DW, Ferman TJ, Benarroch EE, Schmeichel AM, Smith GE, Petersen RC, Ahlskog JE, Matsumoto JY, Knopman DS, Schenck CH, Mahowald MW. Synucleinopathy pathology and REM sleep behavior disorder plus dementia or parkinsonism. Neurology. 2003 Jul 8; 61 (1):40-5
    View PubMed
  107. Boeve BF, Silber MH, Ferman TJ. Melatonin for treatment of REM sleep behavior disorder in neurologic disorders: results in 14 patients. Sleep Med. 2003 Jul; 4 (4):281-4
    View PubMed
  108. Dodick DW, Eross EJ, Parish JM, Silber M. Clinical, anatomical, and physiologic relationship between sleep and headache. Headache. 2003 Mar; 43 (3):282-92
    View PubMed
  109. Silber MH, Richardson JW. Multiple blood donations associated with iron deficiency in patients with restless legs syndrome. Mayo Clin Proc. 2003 Jan; 78 (1):52-4
    View PubMed
  110. Black JL 3rd, Krahn LE, Pankratz VS, Silber M. Search for neuron-specific and nonneuron-specific antibodies in narcoleptic patients with and without HLA DQB1*0602. Sleep. 2002 Nov 1; 25 (7):719-23
    View PubMed
  111. Krahn LE, Pankratz VS, Oliver L, Boeve BF, Silber MH. Hypocretin (orexin) levels in cerebrospinal fluid of patients with narcolepsy: relationship to cataplexy and HLA DQB1*0602 status. Sleep. 2002 Nov 1; 25 (7):733-6
    View PubMed
  112. Ferman TJ, Boeve BF, Smith GE, Silber MH, Lucas JA, Graff-Radford NR, Dickson DW, Parisi JE, Petersen RC, Ivnik RJ. Dementia with Lewy bodies may present as dementia and REM sleep behavior disorder without parkinsonism or hallucinations. J Int Neuropsychol Soc. 2002 Nov; 8 (7):907-14
    View PubMed
  113. Krahn LE, Boeve BF, Oliver L, Silber MH. Hypocretin (orexin) and melatonin values in a narcoleptic-like sleep disorder after pinealectomy. Sleep Med. 2002 Nov; 3 (6):521-3
    View PubMed
  114. Morgenthaler TI, Silber MH. Amnestic sleep-related eating disorder associated with zolpidem. Sleep Med. 2002 Jul; 3 (4):323-7
    View PubMed
  115. Silber MH, Krahn LE, Olson EJ, Pankratz VS. The epidemiology of narcolepsy in Olmsted County, Minnesota: a population-based study. Sleep. 2002 Mar 15; 25 (2):197-202
    View PubMed
  116. Boeve BF, Silber MH, Ferman TJ. Current management of sleep disturbances in dementia. Curr Neurol Neurosci Rep. 2002 Mar; 2 (2):169-77
    View PubMed
  117. Silber MH, Krahn LE, Olson EJ. Diagnosing narcolepsy: validity and reliability of new diagnostic criteria. Sleep Med. 2002 Mar; 3 (2):109-13
    View PubMed
  118. Malik S, Malik S, Boeve BF, Krahn LE, Silber MH. Narcolepsy associated with other central nervous system disorders. Neurology. 2001 Aug 14; 57 (3):539-41
    View PubMed
  119. Silber MH. Commentary on controversies in sleep medicine. Montplaisir et al.: Periodic leg movements are not more prevalent in insomnia or hypersomnia but are specifically associated with sleep disorders involving a dopaminergic mechanism. Sleep Med. 2001 Jul; 2 (4):367-369
    View PubMed
  120. Boeve BF, Silber MH, Ferman TJ, Lucas JA, Parisi JE. Association of REM sleep behavior disorder and neurodegenerative disease may reflect an underlying synucleinopathy. Mov Disord. 2001 Jul; 16 (4):622-30
    View PubMed
  121. Silber MH. Sleep disorders. Neurol Clin. 2001 Feb; 19 (1):173-86
    View PubMed
  122. Krahn LE, Black JL, Silber MH. Narcolepsy: new understanding of irresistible sleep. Mayo Clin Proc. 2001 Feb; 76(2):185-94.
    View PubMed
  123. Klein CJ, Silber MH, Halliwill JR, Schreiner SA, Suarez GA, Low PA. Basal forebrain malformation with hyperhidrosis and hypothermia: variant of Shapiro's syndrome. Neurology. 2001 Jan 23; 56 (2):254-6
    View PubMed
  124. Silber MH, Levine S. Stridor and death in multiple system atrophy. Mov Disord. 2000 Jul; 15 (4):699-704
    View PubMed
  125. Krahn LE, Boeve BF, Olson EJ, Herold DL, Silber MH. A standardized test for cataplexy. Sleep Med. 2000 Apr 1; 1 (2):125-130
    View PubMed
  126. Olson EJ, Boeve BF, Silber MH. Rapid eye movement sleep behaviour disorder: demographic, clinical and laboratory findings in 93 cases. Brain. 2000 Feb; 123 ( Pt 2):331-9
    View PubMed
  127. Hening W, Allen R, Earley C, Kushida C, Picchietti D, Silber M. The treatment of restless legs syndrome and periodic limb movement disorder. Sleep. 1999 Nov 1; 22(7):970-999.
    View PubMed
  128. Ferman TJ, Boeve BF, Smith GE, Silber MH, Kokmen E, Petersen RC, Ivnik RJ. REM sleep behavior disorder and dementia: cognitive differences when compared with AD. Neurology. 1999 Mar 23; 52 (5):951-7
    View PubMed
  129. Dodick DW, Silber MH, Noseworthy JH, Wilbright WA, Rodriguez M. Acute disseminated encephalomyelitis after accidental injection of a hog vaccine: successful treatment with plasmapheresis. Mayo Clin Proc. 1998 Dec; 73(12):1193-5.
    View PubMed
  130. Silber MH. Neurophysiology of Sleep Disorders. Continuum 4:5(Clinical Neurophysiology) (American Academy of Neurology) Baltimore: Williams and Wilkins,. 1998 Oct; 0: 0.
  131. Boeve BF, Silber MH, Ferman TJ, Kokmen E, Smith GE, Ivnik RJ, Parisi JE, Olson EJ, Petersen RC. REM sleep behavior disorder and degenerative dementia: an association likely reflecting Lewy body disease. Neurology. 1998 Aug; 51 (2):363-70
    View PubMed
  132. Silber MH, Shepard JW Jr, Wisbey JA. Pergolide in the management of restless legs syndrome: an extended study. Sleep. 1997 Oct; 20 (10):878-82
    View PubMed
  133. Silber MH. Restless legs syndrome. Mayo Clin Proc. 1997 Mar; 72 (3):261-4
    View PubMed
  134. Poncelet AN, Auger RG, Silber MH. Myokymic discharges of the tongue after radiation to the head and neck. Neurology. 1996 Jan; 46 (1):259-60
    View PubMed
  135. Castle DJ, Silber MH, Handler LC. Carotid artery disease in young adults. S Afr Med J. 1991; 80:278-81.
    View PubMed
  136. Silber MH. Idiopathic acute myelopathy. S Afr Med J. 1990 Feb 3; 77(3):128-30.
    View PubMed
  137. Silber MH. The multiple sleep latency test in the diagnosis of sleep disorders. S Afr Med J. 1990; 77:82-4.
    View PubMed
  138. Silber MH, Wilcox P, Bowen R, Unger A. Neuromyelitis optica (Devic's Syndrome) in association with pulmonary tuberculosis. Neurology. 1990; 40:934-8.
    View PubMed
  139. Silber MH. Syphilitic myelopathy. Genitourinary Med. 1989; 65:338-41.
  140. Silber MH, Sandok BA, Earnest F 4th. Vascular malformations of the posterior fossa. Clinical and radiologic features. Arch Neurol. 1987 Sep; 44(9):965-9.
    View PubMed
  141. Silber MH. Narcolepsy and related disorders. S Afr J Cont Med Educ. 1987; 5:65.
  142. Oswald A, Silber MH, Goldblatt J. Autosomal recessive idiopathic torsion dystonia in a kindred of mixed ancestry. S Afr Med J. 1986; 69:18.
    View PubMed
  143. Silber MH, Jacobs P. Life-threatening haemolytic anemia and infectious mononucleosis. S Afr Med J. 1985; 67:1983.
    View PubMed
  144. Ayzenberg O, Silber MH, Bortz D. Beriberi heart disease: A haemodynamic study. S Afr Med J. 1985; 68:203.
    View PubMed
  145. Silber MH. Acute transverse myelopathy in Epstein-Barr virus infection. S Afr Med J. 1983; 64:753.
    View PubMed