James H. Bower, M.D.

  1. Neurologist
  1. Krzyzanowski B, Mullan AF, Turcano P, Camerucci E, Bower JH, Savica R. Air Pollution and Parkinson Disease in a Population-Based Study. JAMA Netw Open. 2024 Sep 3; 7 (9):e2433602 Epub 2024 Sept 03
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  2. Camerucci E, Mullan AF, Turcano P, Stang CD, Bower J, Benarroch EE, Boeve BF, Savica R. A Population-Based Approach to the Argument on Brain-First and Body-First Pathogenesis of Lewy Body Disease. Ann Neurol. 2024 Sep; 96 (3):551-559 Epub 2024 June 11
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  3. Turcano P, Jacobson J, Ghoniem K, Mullan A, Camerucci E, Stang C, Piat C, Bower JH, Savica R. Impulse control disorders and use of dopamine agonists in early onset Parkinson's disease. Front Neurol. 2024; 15:1404904 Epub 2024 May 22
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  4. Chia NH, McKeon A, Dalakas MC, Flanagan EP, Bower JH, Klassen BT, Dubey D, Zalewski NL, Duffy D, Pittock SJ, Zekeridou A. Stiff person spectrum disorder diagnosis, misdiagnosis, and suggested diagnostic criteria. Ann Clin Transl Neurol. 2023 Jul; 10 (7):1083-1094 Epub 2023 May 22
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  5. Feyissa AM, Bower JH. Evaluation of the Patient With Paroxysmal Spells Mimicking Epileptic Seizures. Neurologist. 2023 Jul 1; 28 (4):207-217 Epub 2023 July 01
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  6. Schipani BE, Bailey ES, Hooshmand SJ, Badihian N, Sandroni P, Benarroch EE, Bower JH, Low PA, Singer W, Coon EA. Sex and Gender Influence Urinary Symptoms and Management in Multiple System Atrophy. J Mov Disord. 2023 May; 16 (2):196-201 Epub 2023 May 24
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  7. Camerucci E, Mullan AF, Bower JH, Bharucha AE, Turcano P, Stang CD, Benarroch EE, Boeve BF, Ahlskog JE, Savica R. Lifelong constipation in Parkinson's disease and other clinically defined alpha-synucleinopathies: A population-based study in Southeast Minnesota. Parkinsonism Relat Disord. 2023 Feb; 107:105244 Epub 2022 Dec 22
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  8. Camerucci E, Mullan AF, Turcano P, Bower J, Piat C, Ahlskog JE, Savica R. 40-Year Incidence of Early-Onset Parkinson's Disease in Southeast Minnesota. J Parkinsons Dis. 2023; 13 (6):893-898
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  9. Piat C, Mullan AF, Stang CD, Hajeb M, Camerucci E, Turcano P, Martin PR, Bower JH, Savica R. Risk of hospitalization in synucleinopathies and impact of psychosis. Front Aging Neurosci. 2023; 15:1274821 Epub 2023 Sept 22
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  10. Chou CZ, Ahlskog JE, Klassen BT, Coon EA, Ali F, Bower JH, Savica R, Hassan A. Utility of routine surface electrophysiology to screen for functional tremor prior to surgical treatment of essential tremor. Clin Park Relat Disord. 2022; 7:100149 Epub 2022 June 16
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  11. Lucien F, Benarroch EE, Mullan A, Ali F, Boeve BF, Mielke MM, Petersen RC, Kim Y, Stang C, Camerucci E, Ross OA, Wszolek ZK, Knopman D, Bower J, Singer W, Savica R. Poly (ADP-Ribose) and alpha-synuclein extracellular vesicles in patients with Parkinson disease: A possible biomarker of disease severity. PLoS One. 2022; 17 (4):e0264446 Epub 2022 Apr 08
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  12. Stang CD, Mullan AF, Camerucci E, Hajeb M, Turcano P, Martin P, Mielke MM, Josephs KA, Splett M, Abler V, Boeve BF, Bower JH, Savica R. Incidence, Prevalence, and Mortality of Psychosis Associated with Parkinson's Disease (1991-2010). J Parkinsons Dis. 2022; 12 (4):1319-1327
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  13. Ayele BA, Zewde YZ, Tafesse A, Sultan A, Friedman JH, Bower JH. Non-Motor Symptoms and Associated Factors in Parkinson's Disease Patients in Addis Ababa, Ethiopia: A Multicenter Cross-Sectional Study. Ethiop J Health Sci. 2021 Jul; 31 (4):837-846
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  14. Ayele BA, Zewde YZ, Tafesse A, Sultan A, Friedman JH, Bower JH. Non-Motor Symptoms and Associated Factors in Parkinson’s Disease Patients in Addis Ababa, Ethiopia: A Multicenter Cross-Sectional Study Ethiop J Health Sci. 2021; 31(1):15.
  15. Bower J, Kumar R, Wszolek Z, Driver-Dunckley E, Hoglinger GU, Litvan I, Mendonca N, Wang D, Zheng H, Rendenbach-Mueller B, Lon HK, Jin Z, Fisseha N, Budur K, Gold M, Ryman D, Florian H. Safety and efficacy of tilavonemab in progressive supranuclear palsy: a phase 2, randomised, placebo-controlled trial. Lancet Neurol. 2021 Mar; 20 (3):182-192
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  16. Budhram A, Simpson HD, Bower JH, Hassan A, Conway BL, Flanagan EP. Holmes Tremor With Perirolandic Demyelinating Lesions: A Distinct Clinicoradiographic Syndrome. Neurology. 2021 Feb 02; 96(5):231-232. Epub 2020 Nov 20.
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  17. Stang CD, Mullan AF, Hajeb M, Camerucci E, Turcano P, Martin P, Mielke MM, Josephs KA, Bower JH, St Louis EK, Boeve BF, Savica R. Timeline of Rapid Eye Movement Sleep Behavior Disorder in Overt Alpha-Synucleinopathies. Ann Neurol. 2021 Feb; 89 (2):293-303 Epub 2020 Nov 20
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  18. Jackson L, Klassen BT, Hassan A, Bower JH, Matsumoto JY, Coon EA, Ali F. Utility of tremor electrophysiology studies. Clin Park Relat Disord. 2021; 5:100108 Epub 2021 Sept 24
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  19. Camerucci E, Stang CD, Turcano P, Tipton PW, Bower JH, Hassan A, Klassen BT, Savica R. Deep Brain Stimulation and Treatment Outcomes of Young- and Late-Onset (=55 Years) Parkinson's Disease: A Population-Based Study. Front Neurol. 2021; 12:784398. Epub 2021 Dec 10.
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  20. Bluett B, Pantelyat AY, Litvan I, Ali F, Apetauerova D, Bega D, Bloom L, Bower J, Boxer AL, Dale ML, Dhall R, Duquette A, Fernandez HH, Fleisher JE, Grossman M, Howell M, Kerwin DR, Leegwater-Kim J, Lepage C, Ljubenkov PA, Mancini M, McFarland NR, Moretti P, Myrick E, Patel P, Plummer LS, Rodriguez-Porcel F, Rojas J, Sidiropoulos C, Sklerov M, Sokol LL, Tuite PJ, VandeVrede L, Wilhelm J, Wills AA, Xie T, Golbe LI. Best Practices in the Clinical Management of Progressive Supranuclear Palsy and Corticobasal Syndrome: A Consensus Statement of the CurePSP Centers of Care. Front Neurol. 2021; 12:694872 Epub 2021 July 01
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  21. Camerucci E, Stang CD, Hajeb M, Turcano P, Mullan AF, Martin P, Ross OA, Bower JH, Mielke MM, Savica R. Early-Onset Parkinsonism and Early-Onset Parkinson's Disease: A Population-Based Study (2010-2015). J Parkinsons Dis. 2021; 11 (3):1197-1207
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  22. Hasan S, Mielke MM, Ahlskog JE, Bower J, Turcano P, Savica R. Infections or Sepsis Preceding Clinically Diagnosed alpha-Synucleinopathies: A Case-Control Study. Mov Disord. 2020 Sep; 35 (9):1684-1689 Epub 2020 June 01
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  23. McCarter SJ, Coon EA, Savica R, St Louis EK, Bower JH, Benarroch EE, Sandroni P, Low P, Singer W. Lower Vitamin B12 Level at Multiple System Atrophy Diagnosis Is Associated With Shorter Survival. Mov Disord. 2020 Aug; 35 (8):1462-1466 Epub 2020 Apr 22
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  24. McCarter SJ, Stang C, Turcano P, Mielke MM, Ali F, Bower JH, Savica R. Higher vitamin B12 level at Parkinson's disease diagnosis is associated with lower risk of future dementia. Parkinsonism Relat Disord. 2020 Apr; 73:19-22 Epub 2020 Mar 16
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  25. Turcano P, Stang CD, Bower JH, Ahlskog JE, Boeve BF, Mielke MM, Savica R. Levodopa-induced dyskinesia in dementia with Lewy bodies and Parkinson disease with dementia. Neurol Clin Pract. 2020 Apr; 10 (2):156-161
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  26. Hasan S, Mielke MM, Turcano P, Ahlskog JE, Bower JH, Savica R. Traumatic brain injury preceding clinically diagnosed alpha-synucleinopathies: A case-control study. Neurology. 2020 Feb 25; 94 (8):e764-e773 Epub 2020 Jan 28
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  27. Stang CD, Turcano P, Mielke MM, Josephs KA, Bower JH, Ahlskog JE, Boeve BF, Martin PR, Upadhyaya SG, Savica R. Incidence and Trends of Progressive Supranuclear Palsy and Corticobasal Syndrome: A Population-Based Study. J Parkinsons Dis. 2020; 10 (1):179-184
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  28. Peterson BJ, Rocca WA, Bower JH, Savica R, Mielke MM. Identifying incident Parkinson's disease using administrative diagnostic codes: a validation study. Clin Park Relat Disord. 2020; 3 Epub 2020 June 02
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  29. Jackson L, Coon EA, Ahlskog JE, Bower JH, Sandroni P, Benarroch EE, Mandrekar JN, Low PA, Singer W. Earlier age of onset in multiple system atrophy with smoking and heavy alcohol use. Parkinsonism Relat Disord. 2019 Sep; 66:212-215 Epub 2019 July 17
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  30. Savica R, Turcano P, Bower JH, Ahlskog JE, Mielke MM. Survival and Progression in Synucleinopathy Phenotypes With Parkinsonism: A Population-Based Study. Mayo Clin Proc. 2019 Sep; 94 (9):1825-1831 Epub 2019 Aug 09
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  31. Melka D, Tafesse A, Bower JH, Assefa D. Prevalence of sleep disorders in Parkinson's disease patients in two neurology referral hospitals in Ethiopia. BMC Neurol. 2019 Aug 22; 19 (1):205
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  32. Ali F, Martin PR, Botha H, Ahlskog JE, Bower JH, Masumoto JY, Maraganore D, Hassan A, Eggers S, Boeve BF, Knopman DS, Drubach D, Petersen RC, Dunkley ED, van Gerpen J, Uitti R, Whitwell JL, Dickson DW, Josephs KA. Sensitivity and Specificity of Diagnostic Criteria for Progressive Supranuclear Palsy. Mov Disord. 2019 Aug; 34 (8):1144-1153 Epub 2019 Feb 06
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  33. Singer W, Dietz AB, Zeller AD, Gehrking TL, Schmelzer JD, Schmeichel AM, Gehrking JA, Suarez MD, Sletten DM, Minota Pacheco KV, Coon EA, Sandroni P, Benarroch EE, Fealey RD, Matsumoto JY, Bower JH, Hassan A, McKeon A, Windebank AJ, Mandrekar JN, Low PA. Intrathecal administration of autologous mesenchymal stem cells in multiple system atrophy. Neurology. 2019 Jul 2; 93 (1):e77-e87 Epub 2019 May 31
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  34. Hirsi JO, Yifru YM, Metaferia GZ, Bower JH. Prevalence of pain in patients with Parkinson's disease in Addis Ababa, Ethiopia. Parkinsonism Relat Disord. 2019 Apr; 61:214-218 Epub 2018 Sept 28
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  35. Hasan S, Mielke MM, Ahlskog JE, Bower J, Turcano P, Savica R. Erectile Dysfunction Preceding Clinically Diagnosed alpha-Synucleinopathies: A Case-Control Study in Olmsted County. Parkinsons Dis. 2019; 2019:6303945 Epub 2019 Apr 09
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  36. Turcano P, Mielke MM, Bower JH, Parisi JE, Cutsforth-Gregory JK, Ahlskog JE, Savica R. Levodopa-induced dyskinesia in Parkinson disease: A population-based cohort study. Neurology. 2018 Dec 11; 91 (24):e2238-e2243 Epub 2018 Nov 07
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  37. Rocca WA, Grossardt BR, Geda YE, Gostout BS, Bower JH, Maraganore DM, de Andrade M, Melton LJ 3rd. Long-term risk of depressive and anxiety symptoms after early bilateral oophorectomy. Menopause. 2018 Nov; 25 (11):1275-1285
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  38. Savica R, Grossardt BR, Rocca WA, Bower JH. Parkinson disease with and without Dementia: A prevalence study and future projections. Mov Disord. 2018 Apr; 33 (4):537-543 Epub 2018 Jan 22
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  39. Hinson SR, Lopez-Chiriboga AS, Bower JH, Matsumoto JY, Hassan A, Basal E, Lennon VA, Pittock SJ, McKeon A. Glycine receptor modulating antibody predicting treatable stiff-person spectrum disorders. Neurol Neuroimmunol Neuroinflamm. 2018 Mar; 5 (2):e438 Epub 2018 Jan 23
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  40. Bower JH, Grossardt BR, Rocca WA, Savica R. Prevalence of and indications for antipsychotic use in Parkinson's disease. Mov Disord. 2018 Feb; 33 (2):325-328 Epub 2017 Dec 26
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  41. Marras C, Beck JC, Bower JH, Roberts E, Ritz B, Ross GW, Abbott RD, Savica R, Van Den Eeden SK, Willis AW, Tanner CM, Parkinson's Foundation P4 Group. Prevalence of Parkinson's disease across North America. NPJ Parkinsons Dis. 2018; 4:21 Epub 2018 July 10
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  42. Turcano P, Mielke MM, Josephs KA, Bower JH, Parisi JE, Boeve BF, Savica R. Clinicopathologic discrepancies in a population-based incidence study of parkinsonism in olmsted county: 1991-2010. Mov Disord. 2017 Oct; 32 (10):1439-1446 Epub 2017 Aug 26
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  43. Mittal SO, Klassen BT, Hassan A, Bower JH, Coon EA. Acute Worsening of Tics on Varenicline. Clin Neuropharmacol. 2017 Sep/Oct; 40 (5):231-232
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  44. Mittal SO, Mack K, Bower JH. Fragile X-associated Tremor/Ataxia Syndrome in an Adolescent Female. Mov Disord Clin Pract. 2017 Sep-Oct; 4 (5):778-780 Epub 2017 June 27
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  45. Savica R, Grossardt BR, Bower JH, Ahlskog JE, Boeve BF, Graff-Radford J, Rocca WA, Mielke MM. Survival and Causes of Death Among People With Clinically Diagnosed Synucleinopathies With Parkinsonism: A Population-Based Study. JAMA Neurol. 2017 Jul 1; 74 (7):839-846
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  46. Savica R, Grossardt BR, Bower JH, Ahlskog JE, Mielke MM, Rocca WA. Incidence and time trends of drug-induced parkinsonism: A 30-year population-based study. Mov Disord. 2017 Feb; 32 (2):227-234 Epub 2016 Oct 25
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  47. Owens E, Josephs KA, Savica R, Hassan A, Klassen B, Bower J, Maraganore D, Matsumoto J, Ahlskog JE. The clinical spectrum and natural history of pure akinesia with gait freezing. J Neurol. 2016 Dec; 263 (12):2419-2423 Epub 2016 Sept 13
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  48. Savica R, Grossardt BR, Bower JH, Ahlskog JE, Rocca WA. Time Trends in the Incidence of Parkinson Disease. JAMA Neurol. 2016 Aug 1; 73 (8):981-9
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  49. Owens E, Krecke K, Ahlskog JE, Fealey R, Hassan A, Josephs KA, Klassen B, Matsumoto J, Bower J. Highly specific radiographic marker predates clinical diagnosis in progressive supranuclear palsy. Parkinsonism Relat Disord. 2016 Jul; 28:107-11 Epub 2016 May 03
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  50. Cutsforth-Gregory JK, Ahlskog JE, McKeon A, Burnett MS, Matsumoto JY, Hassan A, Bower JH. Repetitive exercise dystonia: A difficult to treat hazard of runner and non-runner athletes. Parkinsonism Relat Disord. 2016 Jun; 27:74-80.
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  51. Hassan A, Ahlskog JE, Matsumoto JY, Milber JM, Bower JH, Wilkinson JR. Orthostatic tremor: Clinical, electrophysiologic, and treatment findings in 184 patients. Neurology. 2016 Feb 2; 86 (5):458-64 Epub 2016 Jan 08
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  52. Pillas M, Selai C, Quinn NP, Lees A, Litvan I, Lang A, Bower J, Burn D, Low P, Schrag A. Development and validation of a carers quality-of-life questionnaire for parkinsonism (PQoL Carers). Qual Life Res. 2016 Jan; 25 (1):81-8 Epub 2015 Aug 12
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  53. Coon EA, Sletten DM, Suarez MD, Mandrekar JN, Ahlskog JE, Bower JH, Matsumoto JY, Silber MH, Benarroch EE, Fealey RD, Sandroni P, Low PA, Singer W. Clinical features and autonomic testing predict survival in multiple system atrophy. Brain. 2015 Dec; 138(Pt 12):3623-31. Epub 2015 Sep 13.
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  54. Norby E, Orbelo D, Strand E, Duffy JR, Duffy J, Ekbom D, Bower J, Matsumoto JY, Norby EE. Hyoid muscle dystonia: A distinct focal dystonia syndrome. Parkinsonism Relat Disord. 2015 Oct; 21: (10)1210-3.
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  55. Cutsforth-Gregory JK, Bower JH. Athlete's Dystonia. An Occupational Hazard of Athletes. Minn Med. 2015 Jul; 98(7):42-3.
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  56. O'Gorman CM, Bower JH, Matsumoto JY, Kantarci OH, Kumar N. When Drinking Makes the Tremor Worse: A Task-Specific Orolingual Tremor. Mov Disord Clin Pract. 2014 Sep; 1 (3):237-239 Epub 2014 June 04
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  57. Meta J, Nasuwa F, Mwendo E, Reyburn H, Bower JH. Improving the consent process for neuroepidemiologic research in resource-poor settings. Neurology. 2014 Mar 11; 82 (10):895-7
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  58. Figueroa JJ, Singer W, Parsaik A, Benarroch EE, Ahlskog JE, Fealey RD, Parisi JE, Sandroni P, Mandrekar J, Iodice V, Low PA, Bower JH. Multiple system atrophy: Prognostic indicators of survival. Mov Disord. 2014; 29(9):1151-7.
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  59. Savica R, Grossardt BR, Bower JH, Boeve BF, Ahlskog JE, Rocca WA. Incidence of dementia with Lewy bodies and Parkinson disease dementia. JAMA Neurol. 2013 Nov; 70 (11):1396-402
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  60. Savica R, Grossardt BR, Bower JH, Ahlskog JE, Rocca WA. Incidence and pathology of synucleinopathies and tauopathies related to parkinsonism. JAMA Neurol. 2013 Jul; 70 (7):859-66
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  61. Lee AC, Chin J, Birbeck GL, Bower J, Meyer AC. Creation of the AAN Global Health Section, part II: vision and goals. Neurology. 2013 Jun 4; 80(23):2151-3.
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  62. Lee AC, Chin J, Birbeck GL, Bower J, Meyer AC. Creation of the AAN Global Health Section, Part I: introduction and background. Neurology. 2013 May 28; 80(22):2062-4.
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  63. O'Toole O, Lennon VA, Ahlskog JE, Matsumoto JY, Pittock SJ, Bower J, Fealey R, Lachance DH, McKeon A. Autoimmune chorea in adults. Neurology. 2013 Mar 19; 80 (12):1133-44 Epub 2013 Feb 20
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  64. Savica R, Grossardt BR, Bower JH, Ahlskog JE, Rocca WA. Risk factors for Parkinson's disease may differ in men and women: an exploratory study. Horm Behav. 2013 Feb; 63 (2):308-14 Epub 2012 June 08
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  65. Bower JH, Mwendo E, Walker R, Maro V, Enquosellasie F, Ali S. Validity of a screening instrument for neurologic disability in resource-poor African communities. J Neurol Sci. 2012 Sep 15; 320 (1-2):52-5 Epub 2012 July 11
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  66. Iodice V, Lipp A, Ahlskog JE, Sandroni P, Fealey RD, Parisi JE, Matsumoto JY, Benarroch EE, Kimpinski K, Singer W, Gehrking TL, Gehrking JA, Sletten DM, Schmeichel AM, Bower JH, Gilman S, Figueroa J, Low PA. Autopsy confirmed multiple system atrophy cases: Mayo experience and role of autonomic function tests. J Neurol Neurosurg Psychiatry. 2012 Apr; 83(4):453-9. Epub 2012 Jan 06.
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  67. Savica R, Grossardt BR, Bower JH, Klassen BT, Matsumoto JY. Clinical failure of botulinum toxin A in movement disorders. Parkinsonism Relat Disord. 2012 Jan; 18 (1):73-5 Epub 2011 Aug 30
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  68. Hassan A, Bower JH, Kumar N, Matsumoto JY, Fealey RD, Josephs KA, Ahlskog JE. Dopamine agonist-triggered pathological behaviors: surveillance in the PD clinic reveals high frequencies. Parkinsonism Relat Disord. 2011 May; 17 (4):260-4 Epub 2011 Feb 09
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  69. Hassan A, Bower JH, Kumar N, Matsumoto JY, Fealey RD, Josephs KA, Ahlskog JE. Corrigendum to "Dopamine agonist-triggered pathological behaviors: Surveillance in the PD clinic reveals high frequencies" [Parkinsonism Relat Disord 17 (2011) 260-264]. Parkinsonism Relat Disord. 2011; 17(6):499.
  70. Graff-Radford J, Ahlskog JE, Bower JH, Josephs KA. Dopamine agonists and Othello's syndrome. Parkinsonism Relat Disord. 2010 Dec; 16 (10):680-2 Epub 2010 Sept 09
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  71. Bower JH, Grossardt BR, Maraganore DM, Ahlskog JE, Colligan RC, Geda YE, Therneau TM, Rocca WA. Anxious personality predicts an increased risk of Parkinson's disease. Mov Disord. 2010 Oct 15; 25 (13):2105-13
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  72. Arabia G, Grossardt BR, Colligan RC, Bower JH, Maraganore DM, Ahlskog JE, Geda YE, Rocca WA. Novelty seeking and introversion do not predict the long-term risk of Parkinson disease. Neurology. 2010 Jul 27; 75 (4):349-57
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  73. Schrag A, Sheikh S, Quinn NP, Lees AJ, Selai C, Mathias C, Litvan I, Lang AE, Bower JH, Burn DJ, Low P, Jahanshahi M. A comparison of depression, anxiety, and health status in patients with progressive supranuclear palsy and multiple system atrophy. Mov Disord. 2010 Jun 15; 25(8):1077-81.
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  74. Savica R, Carlin JM, Grossardt BR, Bower JH, Ahlskog JE, Maraganore DM, Bharucha AE, Rocca WA. Medical records documentation of constipation preceding Parkinson disease: A case-control study. Neurology. 2009 Nov 24; 73 (21):1752-8
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  75. Savica R, Grossardt BR, Carlin JM, Icen M, Bower JH, Ahlskog JE, Maraganore DM, Steensma DP, Rocca WA. Anemia or low hemoglobin levels preceding Parkinson disease: a case-control study. Neurology. 2009 Oct 27; 73 (17):1381-7
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  76. Lim SY, Mason WP, Young NP, Chen R, Bower JH, McKeon A, Pittock SJ, Lang AE. Polymyoclonus, laryngospasm, and cerebellar ataxia associated with adenocarcinoma and multiple neural cation channel autoantibodies. Arch Neurol. 2009 Oct; 66(10):1285-7.
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  77. Savica R, Bower JH, Maraganore DM, Grossardt BR, Rocca WA. Bell's palsy preceding Parkinson's disease: a case-control study. Mov Disord. 2009 Jul 30; 24(10):1530-3.
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  78. Grossardt BR, Bower JH, Geda YE, Colligan RC, Rocca WA. Pessimistic, anxious, and depressive personality traits predict all-cause mortality: the Mayo Clinic cohort study of personality and aging. Psychosom Med. 2009 Jun; 71 (5):491-500 Epub 2009 Mar 25
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  79. Bostwick JM, Hecksel KA, Stevens SR, Bower JH, Ahlskog JE. Frequency of new-onset pathologic compulsive gambling or hypersexuality after drug treatment of idiopathic Parkinson disease. Mayo Clin Proc. 2009 Apr; 84 (4):310-6
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  80. McKeon A, Ahlskog JE, Bower JH, Josephs KA, Matsumoto JY. Psychogenic tremor: long-term prognosis in patients with electrophysiologically confirmed disease. Mov Disord. 2009 Jan 15; 24(1):72-6.
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  81. Bower JH, Howlett W, Maro VP, Wangai H, Sirima N, Reyburn H. A screening instrument to measure the prevalence of neurological disability in resource-poor settings. Neuroepidemiology. 2009; 32(4):313-20. Epub 2009 Mar 25.
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  82. McKeon A, Matsumoto JY, Bower JH, Ahlskog JE. The spectrum of disorders presenting as adult-onset focal lower extremity dystonia. Parkinsonism Relat Disord. 2008 Dec; 14(8):613-9. Epub 2008 Mar 07.
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  83. Rocca WA, Grossardt BR, Geda YE, Gostout BS, Bower JH, Maraganore DM, de Andrade M, Melton LJ 3rd. Long-term risk of depressive and anxiety symptoms after early bilateral oophorectomy. Menopause. 2008 Nov-Dec; 15 (6):1050-9
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  84. Rocca WA, Bower JH, Maraganore DM, Ahlskog JE, Grossardt BR, de Andrade M, Melton LJ 3rd. Increased risk of parkinsonism in women who underwent oophorectomy before menopause. Neurology. 2008 Jan 15; 70 (3):200-9 Epub 2007 Aug 29
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  85. McKeon A, Josephs KA, Klos KJ, Hecksel K, Bower JH, Michael Bostwick J, Eric Ahlskog J. Unusual compulsive behaviors primarily related to dopamine agonist therapy in Parkinson's disease and multiple system atrophy. Parkinsonism Relat Disord. 2007 Dec; 13(8):516-9. Epub 2007 Jun 04.
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  86. Arabia G, Grossardt BR, Geda YE, Carlin JM, Bower JH, Ahlskog JE, Maraganore DM, Rocca WA. Increased risk of depressive and anxiety disorders in relatives of patients with Parkinson disease. Arch Gen Psychiatry. 2007 Dec; 64 (12):1385-92
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  87. Owolabi MO, Bower JH, Ogunniyi A. Mapping Africa's way into prominence in the field of neurology. Arch Neurol. 2007 Dec; 64(12):1696-700.
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  88. Rocca WA, Bower JH, Ahlskog JE, Elbaz A, Grossardt BR, McDonnell SK, Schaid DJ, Maraganore DM. Risk of cognitive impairment or dementia in relatives of patients with Parkinson disease. Arch Neurol. 2007 Oct; 64 (10):1458-64
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  89. Rocca WA, Bower JH, Maraganore DM, Ahlskog JE, Grossardt BR, de Andrade M, Melton LJ 3rd. Increased risk of cognitive impairment or dementia in women who underwent oophorectomy before menopause. Neurology. 2007 Sep 11; 69 (11):1074-83 Epub 2007 Aug 29
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  90. McKeon A, Pittock SJ, Glass GA, Josephs KA, Bower JH, Lennon VA, Ahlskog JE. Whole-body tremulousness: isolated generalized polymyoclonus. Arch Neurol. 2007 Sep; 64 (9):1318-22
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  91. Rocca WA, Bower JH, Ahlskog JE, Elbaz A, Grossardt BR, McDonnell SK, Schaid DJ, Maraganore DM. Increased risk of essential tremor in first-degree relatives of patients with Parkinson's disease. Mov Disord. 2007 Aug 15; 22(11):1607-14.
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  92. Zebenigus M, Zenebe G, Bower JH. Neurology training in Africa: the Ethiopian experience. Nat Clin Pract Neurol. 2007 Jul; 3(7):412-3.
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  93. Frigerio R, Breteler MM, de Lau LM, Sanft KR, Bower JH, Ahlskog JE, Grossardt BR, de Andrade M, Maraganore DM, Rocca WA. Number of children and risk of Parkinson's disease. Mov Disord. 2007 Apr 15; 22(5):632-9.
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  94. Bower JH, Asmera J, Zebenigus M, Sandroni P, Bower SM, Zenebe G. The burden of inpatient neurologic disease in two Ethiopian hospitals. Neurology. 2007 Jan 30; 68 (5):338-42
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  95. Okubadejo NU, Bower JH, Rocca WA, Maraganore DM. Parkinson's disease in Africa: A systematic review of epidemiologic and genetic studies. Mov Disord. 2006 Dec; 21 (12):2150-6
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  96. Leibson CL, Long KH, Maraganore DM, Bower JH, Ransom JE, O'Brien PC, Rocca WA. Direct medical costs associated with Parkinson's disease: a population-based study. Mov Disord. 2006 Nov; 21(11):1864-71.
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  97. Frigerio R, Sanft KR, Grossardt BR, Peterson BJ, Elbaz A, Bower JH, Ahlskog JE, de Andrade M, Maraganore DM, Rocca WA. Chemical exposures and Parkinson's disease: a population-based case-control study. Mov Disord. 2006 Oct; 21(10):1688-92.
    View PubMed
  98. Melton LJ 3rd, Leibson CL, Achenbach SJ, Bower JH, Maraganore DM, Oberg AL, Rocca WA. Fracture risk after the diagnosis of Parkinson's disease: Influence of concomitant dementia. Mov Disord. 2006 Sep; 21 (9):1361-7
    View PubMed
  99. Bower JH, Maraganore DM, Peterson BJ, Ahlskog JE, Rocca WA. Immunologic diseases, anti-inflammatory drugs, and Parkinson disease: a case-control study. Neurology. 2006 Aug 8; 67(3):494-6.
    View PubMed
  100. Schrag A, Selai C, Quinn N, Lees A, Litvan I, Lang A, Poon Y, Bower J, Burn D, Hobart J. Measuring quality of life in PSP: the PSP-QoL. Neurology. 2006 Jul 11; 67(1):39-44.
    View PubMed
  101. McDonnell SK, Schaid DJ, Elbaz A, Strain KJ, Bower JH, Ahlskog JE, Maraganore DM, Rocca WA. Complex segregation analysis of Parkinson's disease: The Mayo Clinic Family Study. Ann Neurol. 2006 May; 59 (5):788-95
    View PubMed
  102. Leibson CL, Maraganore DM, Bower JH, Ransom JE, O'brien PC, Rocca WA. Comorbid conditions associated with Parkinson's disease: a population-based study. Mov Disord. 2006 Apr; 21(4):446-55.
    View PubMed
  103. Van Gerpen JA, Kumar N, Bower JH, Weigand S, Ahlskog JE. Levodopa-associated dyskinesia risk among Parkinson disease patients in Olmsted County, Minnesota, 1976-1990. Arch Neurol. 2006 Feb; 63(2):205-9.
    View PubMed
  104. Rocca WA, Grossardt BR, Peterson BJ, Bower JH, Trenerry MR, Ahlskog JE, Sanft KR, de Andrade M, Maraganore DM. The Mayo Clinic cohort study of personality and aging: design and sampling, reliability and validity of instruments, and baseline description. Neuroepidemiology. 2006; 26(3):119-29. Epub 2006 Jan 17.
    View PubMed
  105. Frigerio R, Elbaz A, Sanft KR, Peterson BJ, Bower JH, Ahlskog JE, Grossardt BR, de Andrade M, Maraganore DM, Rocca WA. Education and occupations preceding Parkinson disease: a population-based case-control study. Neurology. 2005 Nov 22; 65 (10):1575-83
    View PubMed
  106. Klos KJ, Bower JH, Josephs KA, Matsumoto JY, Ahlskog JE. Pathological hypersexuality predominantly linked to adjuvant dopamine agonist therapy in Parkinson's disease and multiple system atrophy. Parkinsonism Relat Disord. 2005 Sep; 11 (6):381-6
    View PubMed
  107. Bower JH, Teshome M, Melaku Z, Zenebe G. Frequency of movement disorders in an Ethiopian university practice. Mov Disord. 2005 Sep; 20 (9):1209-13
    View PubMed
  108. Dodd ML, Klos KJ, Bower JH, Geda YE, Josephs KA, Ahlskog JE. Pathological gambling caused by drugs used to treat Parkinson disease. Arch Neurol. 2005 Sep; 62 (9):1377-81 Epub 2005 July 11
    View PubMed
  109. Facheris M, Strain KJ, Lesnick TG, de Andrade M, Bower JH, Ahlskog JE, Cunningham JM, Lincoln S, Farrer MJ, Rocca WA, Maraganore DM. UCHL1 is associated with Parkinson's disease: a case-unaffected sibling and case-unrelated control study. Neurosci Lett. 2005 Jun 10-17; 381(1-2):131-4. Epub 2005 Feb 25.
    View PubMed
  110. Elbaz A, Peterson BJ, Bower JH, Yang P, Maraganore DM, McDonnell SK, Ahlskog JE, Rocca WA. Risk of cancer after the diagnosis of Parkinson's disease: a historical cohort study. Mov Disord. 2005 Jun; 20(6):719-25.
    View PubMed
  111. Liu QR, Walther D, Drgon T, Polesskaya O, Lesnick TG, Strain KJ, de Andrade M, Bower JH, Maraganore DM, Uhl GR. Human brain derived neurotrophic factor (BDNF) genes, splicing patterns, and assessments of associations with substance abuse and Parkinson's Disease. Am J Med Genet B Neuropsychiatr Genet. 2005 Apr 5; 134B (1):93-103
    View PubMed
  112. Kumar N, Van Gerpen JA, Bower JH, Ahlskog JE. Levodopa-dyskinesia incidence by age of Parkinson's disease onset. Mov Disord. 2005 Mar; 20(3):342-4.
    View PubMed
  113. Mamah CE, Lesnick TG, Lincoln SJ, Strain KJ, de Andrade M, Bower JH, Ahlskog JE, Rocca WA, Farrer MJ, Maraganore DM. Interaction of alpha-synuclein and tau genotypes in Parkinson's disease. Ann Neurol. 2005 Mar; 57(3):439-43.
    View PubMed
  114. Bower JH, Zenebe G. Neurologic services in the nations of Africa. Neurology. 2005 Feb 8; 64 (3):412-5
    View PubMed
  115. Rocca WA, Peterson BJ, McDonnell SK, Bower JH, Ahlskog JE, Schaid DJ, Maraganore DM. The Mayo Clinic Family Study of Parkinson's disease: Study design, instruments, and sample characteristics. Neuroepidemiology. 2005; 24(3):151-67.
    View PubMed
  116. Rocca WA, McDonnell SK, Strain KJ, Bower JH, Ahlskog JE, Elbaz A, Schaid DJ, Maraganore DM. Familial aggregation of Parkinson's disease: The Mayo Clinic family study. Ann Neurol. 2004 Oct; 56(4):495-502.
    View PubMed
  117. Maraganore DM, Wilkes K, Lesnick TG, Strain KJ, de Andrade M, Rocca WA, Bower JH, Ahlskog JE, Lincoln S, Farrer MJ. A limited role for DJ1 in Parkinson disease susceptibility. Neurology. 2004 Aug 10; 63(3):550-3.
    View PubMed
  118. Furtado S, Payami H, Lockhart PJ, Hanson M, Nutt JG, Singleton AA, Singleton A, Bower J, Utti RJ, Bird TD, de la Fuente-Femandez R, Tsuboi Y, Klimek ML, Suchowersky O, Hardy J, Calne DB, Wszolek ZK, Farrer M, Gwinn-Hardy K, Stoessl AJ. Profile of families with parkinsonism-predominant spinocerebellar ataxia type 2 (SCA2). Mov Disord. 2004 Jun; 19(6):622-9.
    View PubMed
  119. Maraganore DM, Farrer MJ, Lesnick TG, de Andrade M, Bower JH, Hernandez D, Hardy JA, Rocca WA. Case-control study of the alpha-synuclein interacting protein gene and Parkinson's disease. Mov Disord. 2003 Nov; 18 (11):1233-9
    View PubMed
  120. Lincoln SJ, Maraganore DM, Lesnick TG, Bounds R, de Andrade M, Bower JH, Hardy JA, Farrer MJ. Parkin variants in North American Parkinson's disease: cases and controls. Mov Disord. 2003 Nov; 18(11):1306-11.
    View PubMed
  121. Elbaz A, McDonnell SK, Maraganore DM, Strain KJ, Schaid DJ, Bower JH, Ahlskog JE, Rocca WA. Validity of family history data on PD: evidence for a family information bias. Neurology. 2003 Jul 8; 61 (1):11-7
    View PubMed
  122. Maraganore DM, de Andrade M, Lesnick TG, Farrer MJ, Bower JH, Hardy JA, Rocca WA. Complex interactions in Parkinson's disease: a two-phased approach. Mov Disord. 2003 Jun; 18 (6):631-6
    View PubMed
  123. Bower JH, Maraganore DM, Peterson BJ, McDonnell SK, Ahlskog JE, Rocca WA. Head trauma preceding PD: a case-control study. Neurology. 2003 May 27; 60 (10):1610-5
    View PubMed
  124. Elbaz A, Bower JH, Peterson BJ, Maraganore DM, McDonnell SK, Ahlskog JE, Schaid DJ, Rocca WA. Survival study of Parkinson disease in Olmsted County, Minnesota. Arch Neurol. 2003 Jan; 60 (1):91-6
    View PubMed
  125. Goudreau JL, Maraganore DM, Farrer MJ, Lesnick TG, Singleton AB, Bower JH, Hardy JA, Rocca WA. Case-control study of dopamine transporter-1, monoamine oxidase-B, and catechol-O-methyl transferase polymorphisms in Parkinson's disease. Mov Disord. 2002 Nov; 17 (6):1305-11
    View PubMed
  126. Bower JH, Dickson DW, Taylor L, Maraganore DM, Rocca WA. Clinical correlates of the pathology underlying parkinsonism: a population perspective. Mov Disord. 2002 Sep; 17(5):910-6.
    View PubMed
  127. Elbaz A, Peterson BJ, Yang P, Van Gerpen JA, Bower JH, Maraganore DM, McDonnell SK, Ahlskog JE, Rocca WA. Nonfatal cancer preceding Parkinson's disease: a case-control study. Epidemiology. 2002 Mar; 13 (2):157-64
    View PubMed
  128. Elbaz A, Bower JH, Maraganore DM, McDonnell SK, Peterson BJ, Ahlskog JE, Schaid DJ, Rocca WA. Risk tables for parkinsonism and Parkinson's disease. J Clin Epidemiol. 2002 Jan; 55 (1):25-31
    View PubMed
  129. Benedetti MD, Maraganore DM, Bower JH, McDonnell SK, Peterson BJ, Ahlskog JE, Schaid DJ, Rocca WA. Hysterectomy, menopause, and estrogen use preceding Parkinson's disease: an exploratory case-control study. Mov Disord. 2001 Sep; 16 (5):830-7
    View PubMed
  130. Rocca WA, Bower JH, McDonnell SK, Peterson BJ, Maraganore DM. Time trends in the incidence of parkinsonism in Olmsted County, Minnesota. Neurology. 2001 Aug 14; 57 (3):462-7
    View PubMed
  131. Travis LH, Josephs KA, Bower JH. 25-year-old woman with incoordination and decreased balance. Mayo Clin Proc. 2001 May; 76(5):551-4.
    View PubMed
  132. Benedetti MD, Bower JH, Maraganore DM, McDonnell SK, Peterson BJ, Ahlskog JE, Schaid DJ, Rocca WA. Smoking, alcohol, and coffee consumption preceding Parkinson's disease: a case-control study. Neurology. 2000 Nov 14; 55 (9):1350-8
    View PubMed
  133. Bower JH, Maraganore DM, McDonnell SK, Rocca WA. Influence of strict, intermediate, and broad diagnostic criteria on the age- and sex-specific incidence of Parkinson's disease. Mov Disord. 2000 Sep; 15 (5):819-25
    View PubMed
  134. Shiba M, Bower JH, Maraganore DM, McDonnell SK, Peterson BJ, Ahlskog JE, Schaid DJ, Rocca WA. Anxiety disorders and depressive disorders preceding Parkinson's disease: a case-control study. Mov Disord. 2000 Jul; 15 (4):669-77
    View PubMed
  135. Maraganore DM, Anderson DW, Bower JH, McDonnell SK, Rocca WA. Autopsy patterns for Parkinson's disease and related disorders in Olmsted County, Minnesota. Neurology. 1999 Oct 12; 53 (6):1342-4
    View PubMed
  136. Maraganore DM, O'Connor MK, Bower JH, Kuntz KM, McDonnell SK, Schaid DJ, Rocca WA. Detection of preclinical Parkinson disease in at-risk family members with use of [123I]beta-CIT and SPECT: an exploratory study. Mayo Clin Proc. 1999 Jul; 74 (7):681-5
    View PubMed
  137. Bower JH, Maraganore DM, McDonnell SK, Rocca WA. Incidence and distribution of parkinsonism in Olmsted County, Minnesota, 1976-1990. Neurology. 1999 Apr 12; 52 (6):1214-20
    View PubMed
  138. Bower JH, Maraganore DM, McDonnell SK, Rocca WA. Incidence of progressive supranuclear palsy and multiple system atrophy in Olmsted County, Minnesota, 1976 to 1990. Neurology. 1997 Nov; 49 (5):1284-8
    View PubMed
  139. Bower JH, Hammack JE, McDonnell SK, Tefferi A. The neurologic complications of B-cell chronic lymphocytic leukemia. Neurology. 1997 Feb; 48 (2):407-12
    View PubMed
  140. Ak M, Bower JH, Hoffman SL, Sedegah M, Lees A, Carter M, Beaudoin RL, Charoenvit Y. Monoclonal antibodies of three different immunoglobulin G isotypes produced by immunization with a synthetic peptide or native protein protect mice against challenge with Plasmodium yoelii sporozoites. Infection & Immunity. 1993 Jun; 61(6):2493-7.
    View PubMed
  141. Butterfield JH, Leiferman KM, Abrams J, Silver JE, Bower J, Gonchoroff N, Gleich GJ. Elevated serum levels of interleukin-5 in patients with the syndrome of episodic angioedema and eosinophilia. Blood. 1992 Feb 1; 79 (3):688-92
    View PubMed
  142. Abou-Donia MB, Nomeir AA, Bower JH. Absorption, distribution, excretion and metabolism of a single oral dose of (14C) tri-o-cresyl phosphate (TOCP) on the male rat. Toxicology. 1990; 65(1-2):61-74.
    View PubMed