Precautions
Drug information provided by: Merative, Micromedex®
It is very important that your doctor check your and your child's progress closely while using this medicine to see if it is working properly and to allow for a change in the dose. Blood and urine tests may be needed to check for any unwanted effects.
Do not stop taking this medicine without first checking with your doctor. Stopping a seizure medicine suddenly in a patient who has epilepsy can cause seizures that will not stop (status epilepticus). Your doctor may want you or your child to slowly reduce the amount you are using before stopping completely.
Trimethadione may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed. If you, your child, or your caregiver notice any of these side effects, tell your doctor right away.
This medicine may cause lupus-like and myasthenia-like symptoms. Check with your doctor right away if you or your child has droopy eyelids, rash on the cheeks or other parts of the body, sensitivity of the skin to sunlight, joint or muscle pain, chest pain, swelling of the feet, ankles, and legs, weakness of the arms or legs, trouble swallowing, speech problems, or swollen glands.
Tell your doctor right away if you or your child feels unusually weak, starts bruising easily, has bleeding gums or nosebleeds, seems to be sick more often, has a fever, swollen glands, or a sore throat that will not go away. These could be a signs of a serious problem with the number of blood cells in your body.
Serious skin reactions can occur with this medicine. Check with your doctor right away if you or your child have a severe skin rash, blistering, peeling, or loosening of the skin, red skin lesions, sores or ulcers on the skin, or fever or chills while you or your child are using this medicine.
This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
Check with your doctor before using this medicine with alcohol or other medicines that affect the central nervous system (CNS). The use of alcohol or other medicines that affect the CNS with trimethadione may worsen the side effects of this medicine, such as dizziness, poor concentration, drowsiness, unusual dreams, and trouble with sleeping. Some examples of medicines that affect the CNS are antihistamines or medicine for allergies or colds, sedatives, tranquilizers, or sleeping medicines, medicine for depression, medicine for anxiety, prescription pain medicine or narcotics, medicine for attention deficit and hyperactivity disorder, other medicine for seizures or barbiturates, muscle relaxants, or anesthetics, including some dental anesthetics.
Portions of this document last updated: Feb. 01, 2024
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