Proper Use

Drug information provided by: Merative, Micromedex®

A nurse or other trained health professional will give you this medicine. It is given as a shot under your skin, usually in the thigh, stomach area, or upper arm. This medicine may also be given at home to patients who do not need to be in a hospital or clinic. You or your caregiver may be trained to prepare and inject the medicine at home. Be sure that you understand how to use the medicine.

This medicine should come with a patient information leaflet and patient instructions. Read and follow these instructions carefully. Ask your doctor if you have any questions.

If you use Adbry® at home, you will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas. This will help prevent skin problems. Do not inject into skin areas that are tender, damaged, bruised, or scarred.

This medicine comes in 2 forms: an autoinjector and prefilled syringe.

Allow the autoinjector to warm to room temperature for 45 minutes and prefilled syringe to warm to room temperature for 30 minutes before using it. Do not warm using heat sources (eg, microwave, hot water, sunlight).

To use the autoinjector:

  • Wash your hands with soap and water before and after using this medicine.
  • Do not shake the autoinjector. Do not remove the cap until you are ready to use it.
  • Do not use the autoinjector if it looks damaged or has been dropped.
  • Check the liquid in the autoinjector. It should be clear to slightly pearly and colorless to pale yellow. Do not use it if it is cloudy, discolored, or has particles in it.
  • Hold the autoinjector with one hand and pull the cap straight off with your other hand. Do not recap. Do not touch or push the needle guard with your finger.
  • Place the needle guard flat against your skin at a 90-degree angle. Do not change the position of the autoinjector after injection has started.
  • Press the autoinjector down firmly and hold it in place. You will hear a "click" to let you know that the injection has started and the yellow plunger will start to move. It will take up to 15 seconds to inject the full dose. You will hear a second "click" when the yellow plunger fills the viewing window. Continue to press for another 5 seconds to make sure you get the full dose.

Check the liquid in the prefilled syringe. It should be clear and colorless to pale yellow. Do not use it if it is cloudy, discolored, or has particles in it. Do not shake.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For moderate to severe atopic dermatitis:
    • For injection dosage form (autoinjector):
      • Adults—At first, 600 milligrams (mg) (two 300 mg injections) injected under the skin at different injection sites. Then, your dose will be reduced to 300 mg every other week.
      • Children 12 to 17 years of age—Use of prefilled syringe is recommended.
      • Children younger than 12 years of age—Use and dose must be determined by your doctor.
    • For injection dosage form (prefilled syringe):
      • Adults—At first, 600 milligrams (mg) (four 150 mg injections) injected under the skin at different injection sites. Then, your dose will be reduced to 300 mg (two 150 mg injections) every other week.
      • Children 12 to 17 years of age—At first, 300 mg (two 150 mg injections) injected under the skin at different injection sites. Then, your dose will be reduced to 150 mg every other week.
      • Children younger than 12 years of age—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store in the refrigerator. Do not freeze.

Protect the medicine from direct light. Keep the medicine in the original package until you are ready to use it. Do not use it if it has been frozen. You may store the autoinjector or prefilled syringe at room temperature for up to 14 days. Do not put the medicine back in the refrigerator. Throw the medicine away if it has been left out of the refrigerator for more than 14 days.

Throw away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.

Portions of this document last updated: July 01, 2024

Copyright: © Merative US L.P. 1973, 2024. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.