Proper Use

Drug information provided by: Merative, Micromedex®

This medicine is given as a shot under your skin in the stomach, thigh, or upper arm. It may sometimes be given at home to patients who do not need to be in the hospital or clinic. If you are using this medicine at home, your doctor or nurse will teach you how to prepare and inject the medicine. Be sure that you understand how to use this medicine.

If you use this medicine at home, you will be shown the body areas where this shot can be given. Use a different body area each time you give yourself or your child a shot. Keep track of where you give each shot to make sure you rotate body areas. This will help prevent skin problems. Do not inject into skin areas that are bruised, infected, irritated, red, tender, swollen, or painful.

This medicine comes with a patient information leaflet and patient instructions. Read and follow the instructions carefully. Ask your doctor if you have any questions about:

  • How to prepare the injection.
  • The proper use of disposable syringes.
  • How to give the injection.
  • How long the injection can be stored at home.

Allow the medicine to warm to room temperature for 15 minutes before using it. Do not warm it by using a heat source (eg, hot water or microwave) or in any other way. Do not shake.

Check the liquid in the vial. It should be colorless or slightly yellow. Do not use this medicine if it is cloudy, discolored, or if it has particles in it. Do not use the prefilled syringe if it has been damaged or cracked.

Use a new needle and syringe each time you inject your medicine.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For injection dosage form (solution):
    • For hereditary angioedema:
      • Adults and children 12 years of age and older—At first, 300 milligrams (mg) injected under the skin every 2 weeks. 300 mg every 4 weeks may also be given if the patient is well controlled (attack free) for more than 6 months.
      • Children 6 to less than 12 years of age—At first, 150 mg injected under the skin every 4 weeks. 150 mg every 4 weeks may also be given if the patient is well controlled (attack free) for more than 6 months.
      • Children 2 to less than 6 years of age—150 mg injected under the skin every 4 weeks.
      • Children younger than 2 years of age—Use and dose must be determined by your doctor.

Missed Dose

Call your doctor or pharmacist for instructions.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store in the refrigerator. Do not freeze.

Keep it in its original container. Protect from light. Do not use it if it has been frozen or thawed.

Use this medicine within 2 hours after preparing it at room temperature. You may also refrigerate the prepared dosing syringe and use it within 8 hours.

Throw away used syringes in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.