Acetaminophen (intravenous route)

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of acetaminophen injection for the treatment of acute pain in children 2 years of age and older. However, safety and efficacy have not been established in children younger than 2 years of age.

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of acetaminophen injection for the treatment of fever in children and premature infants 32 weeks of age and older. However, safety and efficacy have not been established in children and premature infants younger than 32 weeks of age.

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of acetaminophen injection in the elderly.

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Carbamazepine
• Imatinib
• Isoniazid
• Pixantrone
• Pneumococcal 13-Valent Vaccine, Diphtheria Conjugate

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Acenocoumarol
• Fosphenytoin
• Lixisenatide
• Phenytoin
• Warfarin
• Zidovudine

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

• Ethanol
• Tobacco

Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

• Cabbage

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Alcohol abuse, history of or
• Hypovolemia (low blood volume), severe or
• Kidney disease, severe or
• Liver disease or
• Malnourished condition—Use with caution. May increase risk for more serious side effects.

• Liver disease, active and severe—Should not be used in patients with this condition.

Less common-Adults

• Abnormal breath sounds
• bloating or swelling of the face, arms, hands, lower legs, or feet
• difficult or labored breathing
• difficulty opening the mouth
• dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• irregular heartbeat
• lockjaw
• loss of appetite
• muscle pain or cramps
• muscle spasm, especially of the neck and back
• nausea or vomiting
• nervousness
• numbness or tingling in the hands, feet, or lips
• pain at the injection site
• slow or fast heartbeat
• sweating
• tightness in the chest
• unusual tiredness or weakness

Less common-Children

• Decreased urination
• difficult, fast, or noisy breathing, sometimes with wheezing
• dizziness
• fast, slow, pounding, or irregular heartbeat or pulse
• lower back, side, or stomach pain
• muscle spasms (tetany) or twitching
• noisy breathing
• pain in the arms or legs
• swelling around the eyes
• swelling of the feet, ankles, or lower legs

Incidence not known

• Abdominal or stomach pain or tenderness
• clay colored stools
• dark urine
• decreased appetite
• difficulty with swallowing
• flu-like symptoms
• loss of appetite
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• right upper stomach tenderness
• skin rash, itching, or hives
• tightness in the chest
• yellow eyes or skin

Symptoms of overdose

• Black, tarry stools
• bleeding gums
• bloating of the abdomen or stomach
• blood in the urine or stools
• chills
• difficult or painful urination
• general feeling of discomfort or illness
• light-colored stools
• pinpoint red spots on the skin
• sudden decrease in the amount of urine
• unpleasant breath odor
• vomiting of blood

More common

• Trouble sleeping

Less common-Adults

• Fear

Less common-Children

• Diarrhea
• difficulty having a bowel movement (stool)
• irritability
• restlessness