Overview

Diverticulitis is inflammation of irregular bulging pouches in the wall of the large intestine.

Typically, the wall of the large intestine, also called the colon, is smooth. An irregular, bulging pouch in the colon wall is called a diverticulum. Multiple pouches are called diverticula.

Diverticula are common, especially after age 50. They are usually found in the lower part of the colon. Most often, they don't cause problems. The presence of diverticula is called diverticulosis. Diverticulosis isn't a disease condition.

When these pouches become inflamed, the condition is called diverticulitis. Inflammation is immune system activity that increases blood flow and fluids to a site in the body and delivers disease-fighting cells. Inflammation of diverticula can cause severe pain, fever, nausea and changes in your stool habits.

Mild diverticulitis is usually treated with rest, changes in your diet and possibly antibiotics. Severe diverticulitis usually needs antibiotic treatment in the hospital. Surgery may be needed for severe or frequent diverticulitis.

Symptoms

A common symptom of diverticulitis is pain in the area below the chest called the abdomen. Most often, pain is in the lower left abdomen.

Pain from diverticulitis is usually sudden and intense. Pain may be mild and gradually worsen, or the intensity of the pain may vary over time.

Other signs and symptoms of diverticulitis may include:

  • Nausea.
  • Fever.
  • Tenderness in the abdomen when touched.
  • Changes in stool, including sudden diarrhea or constipation.

When to see a doctor

Get medical care anytime you have constant, unexplained abdominal pain, particularly if you also have a fever and notable changes in stools.

Get the latest health information from Mayo Clinic delivered to your inbox.

Subscribe for free and receive your in-depth guide to digestive health, plus the latest on health innovations and news. You can unsubscribe at any time. Click here for an email preview.

To provide you with the most relevant and helpful information, and understand which information is beneficial, we may combine your email and website usage information with other information we have about you. If you are a Mayo Clinic patient, this could include protected health information. If we combine this information with your protected health information, we will treat all of that information as protected health information and will only use or disclose that information as set forth in our notice of privacy practices. You may opt-out of email communications at any time by clicking on the unsubscribe link in the e-mail.

Causes

Diverticula gradually develop over time in the walls of the colon. They are common in older adults. Pressure in the colon — possibly from spasms or straining — may cause diverticula to form where the wall of the colon is weak.

Diverticulitis is inflammation of one or more diverticula. This may happen because of bacterial disease or damage to diverticula tissues.

Risk factors

Diverticulitis is more common among people over 50. Other factors that increase the risk of diverticulitis include:

  • Obesity.
  • Smoking.
  • A diet of low-fiber foods.
  • A diet high in red meat.
  • Heavy alcohol use.
  • Lack of exercise.
  • Low vitamin D levels.
  • Certain medicines, such as steroids, opioids and nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen (Advil, Motrin IB, others) and naproxen sodium (Aleve).

Complications

About 15 percent of people with diverticulitis develop complications. These may include:

  • A pocket of pus from bacterial disease, called an abscess.
  • Blockage of the colon.
  • An irregular passageway, called a fistula, between the bowel and another organ in the body.
  • A tear in the colon wall that allows waste to spill out, causing serious disease of the abdomen lining, called peritonitis.
  • Bleeding from ruptured blood vessels, also called diverticular hemorrhage.

Prevention

To help prevent diverticulitis:

  • Exercise regularly. Regular, vigorous exercise decreases the risk of diverticulitis.
  • Eat a high-fiber diet. A high-fiber diet improves the movement of waste through the colon and decreases the risk of diverticulitis. Fiber-rich foods include fruits, vegetables, whole grains, seeds and beans. Cut back on red meats and sweets.
  • Maintain a healthy weight. Talk to your healthcare professional or a dietitian about goals for a healthy weight for you and strategies to reach your goals.
  • Drink plenty of fluids. Fiber works by absorbing water and increasing the soft, bulky waste in your colon. Drinking fluids improves the movement of waste and prevents constipation.
  • Quit smoking and limit alcohol use. Smoking and heavy alcohol use are associated with an increased risk of diverticulitis.

In the past, healthcare professionals recommended that people with diverticulitis avoid nuts, seeds and popcorn. Studies have shown that these foods do not increase the risk of diverticulitis. Seeds and some nuts are good sources of fiber.

Oct. 22, 2024
  1. AskMayoExpert. Diverticulitis. Mayo Clinic; 2023.
  2. Diverticular disease. National Institute of Diabetes and Digestive and Kidney Diseases. https://www.niddk.nih.gov/health-information/digestive-diseases/diverticulosis-diverticulitis/all-content. Accessed March 22, 2024.
  3. Gunby SA, et al. Acute colonic diverticulitis. Annals of Internal Medicine. 2024; doi:10.7326/AITC202403190.
  4. Ferri FF. Diverticular disease (diverticulosis, diverticulitis, diverticular hemorrhage). In: Ferri's Clinical Advisor 2024. Elsevier; 2024. https://www.clinicalkey.com. Accessed March 25, 2024.
  5. Diverticulosis and diverticulitis. American College of Gastroenterology. https://gi.org/topics/diverticulosis-and-diverticulitis/. Accessed March 22, 2024.
  6. Peery AF, et al. AGA clinical practice update on medical management of colonic diverticulitis: Expert review. Gastroenterology. 2021; doi:10.1053/j.gastro.2020.09.059.
  7. Ami TR. Allscripts EPSi. Mayo Clinic. April 17, 2024.