Research

Comprehensive research is an integral part of Mayo Clinic. The Cellular and Molecular Immunology Laboratory within the Primary Immunodeficiency Center has advanced the development of several diagnostic and prognostic tests that help provide answers for patients with immunodeficiency.

Researchers continue to develop new diagnostic tests for several immunodeficiencies in the sample repository within the Cellular and Molecular Immunology Laboratory. The sample repository was developed by Mayo Clinic staff to help support research and facilitate advancement in clinical practice. Blood samples from adult and pediatric patients with a variety of primary immunodeficiencies are kept in the repository and are used for research as well as clinical validation of new diagnostic tests.

The center combines laboratory-based work and clinical research. Such collaboration enables efforts such as the study of antibody responses to a pneumonia vaccine, which is a commonly used diagnostic test for several primary immunodeficiencies.

Mayo Clinic collaborates closely with other immunodeficiency research and patient-oriented support organizations. Mayo Clinic is a designated Jeffrey Modell Foundation Diagnostic and Research Center. The Jeffrey Modell Foundation is a nonprofit organization promoting and conducting research for primary immunodeficiency through a worldwide network of diagnostic and research centers. Since 2007, the Primary Immunodeficiency Center at Mayo Clinic has been a referral center for the Jeffrey Modell Foundation.

Mayo Clinic also is a part of the Primary Immune Deficiency Treatment Consortium.

Publications

See a list of publications about primary immunodeficiency by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.