Neuromuscular Disease Overview

Neuromuscular diseases affect the function of muscles due to problems with the nerves and muscles in your body. The most common sign of these diseases is muscle weakness.

Mayo Clinic neurologists provide comprehensive evaluation of these diseases, including electrodiagnostic studies and other tests.

Conditions and symptoms

Research advances that improve clinical care

Doctors are active in clinical and laboratory research to improve the diagnosis and treatment of people with neuromuscular diseases.

Read about research in neuromuscular diseases and ALS.

Nationally recognized expertise

Mayo Clinic in Rochester, Minnesota, Mayo Clinic in Phoenix/Scottsdale, Arizona, and Mayo Clinic in Jacksonville, Florida, rank among the Best Hospitals for neurology and neurosurgery in the U.S. News & World Report Best Hospitals rankings. Mayo Clinic Children's Center in Rochester is ranked the No. 1 hospital in Minnesota, and the five-state region of Iowa, Minnesota, North Dakota, South Dakota and Wisconsin, according to U.S. News & World Report's 2024-2025 "Best Children's Hospitals" rankings.