Clinical trials Below are current clinical trials.87 studies in Cardiovascular Medicine (open studies only). Filter this list of studies by location, status and more. Left Atrial Appendage Exclusion for Prophylactic Stroke Reduction Trial Rochester, Minn. The objective of this trial is to evaluate the effectiveness of left atrial appendage exclusion (LAAE) for the prevention of ischemic stroke or systemic arterial embolism in subjects undergoing cardiac surgery who have risk factors for atrial fibrillation and ischemic stroke. the Mayo Cardiac Sarcoid Registry Rochester, Minn., Jacksonville, Fla. Aims, purpose, or objectives: Develop a retrospective registry of patients with cardiac sarcoidosis Develop a prospective registry of patients with cardiac sarcoidosis Understand the natural history of cardiac sarcoidosis through evaluation of outcomes of patients in the registry Determine risk factors for sarcoid involvement of the heart Evaluate outcomes of patients both treated and untreated with cardiac sarcoidosis Understand the complications of untreated and treated cardiac sarcoidosis A Study to Identify the Genetic Defect(s) in Individuals with Arrhythmogenic Bi-Leaflet Mitral Prolapse (aBiMVP) Rochester, Minn. The purpose of this study is to elucidate the genetic basis of aBiMVP in hopes of determining novel mechanisms that underlie aBiMVP pathogenesis. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial Scottsdale/Phoenix, Ariz. Carotid revascularization for primary prevention of stroke (CREST-2) is two independent multicenter, randomized controlled trials of carotid revascularization and intensive medical management versus medical management alone in patients with asymptomatic high-grade carotid stenosis. One trial will randomize patients in a 1:1 ratio to endarterectomy versus no endarterectomy and another will randomize patients in a 1:1 ratio to carotid stenting with embolic protection versus no stenting. Medical management will be uniform for all randomized treatment groups and will be centrally directed. A Study to Compare the Effectiveness of Different High-intensity Interval Training Programs in Cardiac Rehabilitation Rochester, Minn. The main purpose of the study is to examine the effect of two different high intensity interval training (HIIT) prescription approaches on improving fitness, heart function, and the ability of the body's muscles to receive oxygen. The two approaches of the same total exercise durston will include: 1) HIIT with progressively increased interval durations (PRO-HIIT) versus 2) HIIT with constant shorter interval durations (CON-HIIT). The study hypothesis is that the progressively increased interval duration at high-intensity (PRO-HIIT) will result in a greater increases in fitness, heart function, and the ability of the body's muscles to receive oxygen in patients enrolled in cardiac rehabilitation. A Study of Sexual Dysfunction in Patients with Hypertrophic Obstructive Cardiomyopathy Undergoing Septal Myectomy Rochester, Minn. The purpose of this study is to determine how many patients suffer from sexual function problems and ascertain if they are improved or modified by cardiac surgical intervention. Hospital Diuretic Therapy and Associated Risk of Heart Failure in Treating Fluid Volume Overload Rochester, Minn. The objective of this proposal is to assess blood-plasma volume (TBV-PV) status quantitatively in patients with DHF admitted to hospital for volume management, and to determine how effective standard diuretic therapy is in achieving euvolemia and the impact of their quantitated volume status at the time of hospital discharge on heart failure related morality and re-hospitalizations. Thus, to determine if quantitative blood volume analysis could potentially serve as an effective tool to guide more effective in-hospital diuretic therapy to achieve better outcomes in patients hospitalized with clinically identified volume overload. A Repository of Atria Tissue for the Investigation of Atrial Pathophysiology in Patients with Atrial Fibrillation Rochester, Minn. The purpose of this study is to collect surgically removed atrial tissue for genetic, pathologic, metabolic, and molecular studies in patients with or without a history of atrial fibrillation. A Study to Evaluate Perceptions of Midline Sternotomy Scar in Children and Young Adults Rochester, Minn. The purpose of this study is to evaluate how children and young adults perceive their midline sternotomy scars (in terms of appearance, associated symptoms, consciousness, satisfaction with appearance/symptoms, and impact on quality of life)? A Study to Establish a Registry for the Pulmonary Hypertension Association Jacksonville, Fla. The objectives of this study are to measure and improve quality of care (including assessing differences in adherence to evidence-based guidelines and establishing benchmarks for health outcomes); determine the clinical effectiveness, comparative effectiveness, and cost effectiveness of treatment approaches; understand risk factors for outcomes and regional/center differences; and facilitate funded clinical trials of new therapies and collaboration with the PAH community at large, including providers, patients, and their caregivers. Pagination Clinical studies PrevPrevious Page Go to page 33 Go to page 44 Go to page 55 Go to page 66 Go to page 77 NextNext Page Request an appointment Expertise & rankingsResearch March 16, 2024 Share on: FacebookTwitter Mayo Clinic in Rochester, Minnesota, has been recognized as one of the top Cardiology & Heart Surgery hospitals in the nation for 2024-2025 by U.S. News & World Report. Learn more about this top honor Cardiovascular MedicineDepartmenthomeSectionsOverviewRequest an appointmentTests & proceduresConditions treatedDoctorsSpecialty groupsExpertise & rankingsClinical trialsResearchPatient storiesCosts & insuranceNews from Mayo ClinicReferrals Research: It's all about patients Show transcript for video Research: It's all about patients [MUSIC PLAYING] Joseph Sirven, M.D., Professor of Neurology, Mayo Clinic: Mayo's mission is about the patient. The patient comes first. So the mission and research here is to advance how we can best help the patient, how to make sure the patient comes first in care. So in many ways, it's a cycle. It can start with as simple as an idea worked on in a laboratory, brought to the patient bedside, and if everything goes right — and let's say it's helpful or beneficial — then brought on as a standard approach. And I think that is one of the unique characteristics of Mayo's approach to research — that patient-centeredness — that really helps to put it in its own spotlight. SectionsRequest an appointmentOverviewTests & proceduresConditions treatedDoctorsSpecialty groupsExpertise & rankingsClinical trialsResearchPatient storiesCosts & insuranceNews from Mayo ClinicReferrals ORG-20121929 Medical Departments & Centers Cardiovascular Medicine